CN103651467B - A kind of bactericidal composition containing Hexanaphthene flusulfamide - Google Patents
A kind of bactericidal composition containing Hexanaphthene flusulfamide Download PDFInfo
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- CN103651467B CN103651467B CN201210319682.3A CN201210319682A CN103651467B CN 103651467 B CN103651467 B CN 103651467B CN 201210319682 A CN201210319682 A CN 201210319682A CN 103651467 B CN103651467 B CN 103651467B
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Abstract
The invention discloses a kind of bactericidal composition containing Hexanaphthene flusulfamide, bactericidal composition containing active components A and active component B, active components A is selected from Hexanaphthene flusulfamide, active component B is selected from any one compound following: cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb, and the weight ratio of active components A and active component B is 1: 70 ~ 70: 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious synergistic effect, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition in crop pest containing Hexanaphthene flusulfamide.
Technical background
Hexanaphthene flusulfamide chemical name: N-(2-trifluoromethyl-4-chlorophenyl)-a-oxocyclohexyl sulfonamide.It has stronger prevention, treatment and osmotically active, and has higher lasting effect.Show through field test results, Hexanaphthene flusulfamide can prevent and treat gray mold, sclerotinia rot of colza, Cucumber Target Leaf Spot and scab effectively.
The salt of metalaxyl is Metalaxyl-M.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find Hexanaphthene flusulfamide and cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb mutually composite, there is good synergistic effect within the specific limits, and about Hexanaphthene flusulfamide and cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb relevant composite, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind of to there is the bactericidal composition containing Hexanaphthene flusulfamide that synergistic function, use cost are low, preventive effect is good.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition containing Hexanaphthene flusulfamide, containing active components A and active component B, active components A and active component B weight ratio are 1: 70 ~ 70: 1, described active components A is selected from Hexanaphthene flusulfamide, and active component B is selected from the one in cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb; The weight ratio being preferably active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1; The weight ratio being more preferably Hexanaphthene flusulfamide and cyazofamid is 1: 10 ~ 30: 1, the weight ratio of Hexanaphthene flusulfamide and dimethomorph is 1: 10 ~ 20: 1, the weight ratio of Hexanaphthene flusulfamide and metalaxyl or its salt is 1: 20 ~ 10: 1, the weight ratio of Hexanaphthene flusulfamide and Propamocarb is 1: 20 ~ 10: 1, the weight ratio of Hexanaphthene flusulfamide and white urea cyanogen is 1: 10 ~ 20: 1, and the weight ratio of Hexanaphthene flusulfamide and iprovalicarb is 1: 10 ~ 20: 1; The weight ratio most preferably being Hexanaphthene flusulfamide and cyazofamid is 1: 4 ~ 19: 1, the weight ratio of Hexanaphthene flusulfamide and dimethomorph is 1: 4 ~ 9: 1, the weight ratio of Hexanaphthene flusulfamide and metalaxyl or its salt is 1: 9 ~ 4: 1, the weight ratio of Hexanaphthene flusulfamide and Propamocarb is 1: 9 ~ 4: 1, the weight ratio of Hexanaphthene flusulfamide and white urea cyanogen is 1: 4 ~ 9: 1, and the weight ratio of Hexanaphthene flusulfamide and iprovalicarb is 1: 4 ~ 9: 1.
The described bactericidal composition containing Hexanaphthene flusulfamide, composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, can also make aqua.
The described bactericidal composition containing Hexanaphthene flusulfamide is for preventing and treating the disease of crop; Described crop comprises cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease comprises gray mold, brown spot, scab, rust, stalk break, downy mildew, peronospora tabacina, epidemic disease, damping off, balck shank, rust.
In bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active component, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, antifreeze, disintegrant, defoamer etc.According to different dosage form, can also containing antifreeze known in those skilled in the art etc. in preparation.
Composition comprises following component and content when making wetting powder: active components A 0.5% ~ 70%, active component B 0.5% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 0.5% ~ 70%, active component B 0.5% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as gray mold, brown spot, scab, rust, stalk break, downy mildew, peronospora tabacina, epidemic disease, damping off, balck shank, rust etc. have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.Application Example one
Embodiment 1 ~ 18 wetting powder
By Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1,2,3.
The each component of table 1 embodiment 1 ~ 6 and content
The each component of table 2 embodiment 7 ~ 12 and content
The each component of table 3 embodiment 13 ~ 18 and content
Embodiment 19 ~ 36 water dispersible granules
Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 4,5,6.
The each component of table 4 embodiment 19 ~ 24 and content
The each component of table 5 embodiment 25 ~ 30 and content
The each component of table 6 embodiment 31 ~ 36 and content
Embodiment 37 ~ 54 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add Hexanaphthene flusulfamide, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 7,8,9.
The each component of table 7 embodiment 37 ~ 42 and content
The each component of table 8 embodiment 43 ~ 48 and content
The each component of table 9 embodiment 49 ~ 54 and content
Embodiment 55 ~ 66 aqueous emulsion
Hexanaphthene flusulfamide, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 10,11.
The each component of table 10 embodiment 55 ~ 60 and content
The each component of table 11 embodiment 61 ~ 66 and content
Cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb in table 1 ~ 11 are exchanged, can novel formulation be obtained.
Embodiment 67 ~ 69 microemulsion
Hexanaphthene flusulfamide, active component B are dissolved in and are equipped with in the homogenizer of solvent, by emulsifier, antifreeze (can add and can not add), defoamer, join above-mentioned solution is housed homogenizer in, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 12.
The each component of table 12 embodiment 67 ~ 69 and content
Embodiment 70 ~ 72 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add Hexanaphthene flusulfamide, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained Hexanaphthene flusulfamide suspending agent, then by active component B, emulsifier, solvent and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 13.
The each component of table 13 embodiment 70 ~ 72 and content
In table 13, active component B is cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb.
Embodiment 73 ~ 75 microcapsule suspending agent
By Hexanaphthene flusulfamide, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 14.
The each component of table 14 embodiment 73 ~ 75 and content
Embodiment 76 ~ 78 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add Hexanaphthene flusulfamide, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 15.
The each component of table 15 embodiment 76 ~ 78 and content
In table 15, active component B is cyazofamid, dimethomorph, metalaxyl or its salt, white urea cyanogen, iprovalicarb.
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is Hexanaphthene flusulfamide;
B is selected from the one in cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, iprovalicarb.Application Example two:
For examination disease: downy mildew of garpe, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination Hexanaphthene flusulfamide and cyazofamid different ratio mixture.
Toxicity test result
Table 16 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to downy mildew of garpe of cyazofamid
As shown in Table 16, Hexanaphthene flusulfamide and the composite proportioning of preventing and treating downy mildew of garpe of cyazofamid are when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and cyazofamid is 1: 10 ~ 30: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and cyazofamid is 30 ︰ 1,25 ︰ 1,24 ︰ 1,20 ︰ 1,15 ︰ 1,14 ︰ 1,13 ︰ 1,12 ︰ 1,11 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,1 ︰ 1,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10, when wherein Hexanaphthene flusulfamide and cyazofamid weight ratio are 5:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: tomato blight, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of dimethomorph and the two different ratio mixture
Toxicity test result
Table 17 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to tomato blight of dimethomorph
As shown in Table 17, the proportioning of Hexanaphthene flusulfamide and the composite control tomato blight of dimethomorph is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and dimethomorph is at 1 ︰ 10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and dimethomorph is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,1 ︰ 1,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10, when wherein Hexanaphthene flusulfamide and dimethomorph weight ratio are 2:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: cucumber downy mildew, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and metalaxyl or the former medicine of its salt and the two different ratio mixture.
Toxicity test result
Table 18 Hexanaphthene flusulfamide and metalaxyl or the composite toxicity test analysis of results table to cucumber downy mildew of its salt
As shown in Table 18, the proportioning of Hexanaphthene flusulfamide and metalaxyl or the composite control cucumber downy mildew of its salt is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and metalaxyl or its salt is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and metalaxyl or its salt is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein Hexanaphthene flusulfamide and metalaxyl or its salt weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: cucumber downy mildew, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of Propamocarb and the two different ratio mixture.
Toxicity test result
Table 19 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to cucumber downy mildew of Propamocarb
As shown in Table 19, the proportioning of Hexanaphthene flusulfamide and the composite control cucumber downy mildew of Propamocarb is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and Propamocarb is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and Propamocarb is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein Hexanaphthene flusulfamide and Propamocarb weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: downy mildew of garpe, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of white urea cyanogen and the two different ratio mixture.
Toxicity test result
Table 20 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to downy mildew of garpe of white urea cyanogen
As shown in Table 20, Hexanaphthene flusulfamide and the composite proportioning of preventing and treating downy mildew of garpe of white urea cyanogen are when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and white urea cyanogen is 1: 10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and white urea cyanogen is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10, when wherein Hexanaphthene flusulfamide and white urea cyanogen weight ratio are 2:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For examination disease: cucumber downy mildew, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of iprovalicarb and the two different ratio mixture.
Toxicity test result
Table 21 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to cucumber downy mildew of iprovalicarb
As shown in Table 21, the proportioning of Hexanaphthene flusulfamide and the composite control cucumber downy mildew of iprovalicarb is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and iprovalicarb is 1: 10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and iprovalicarb is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10, when wherein Hexanaphthene flusulfamide and iprovalicarb weight ratio are 3:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: Hexanaphthene flusulfamide and active component B composite after have obvious synergistic effect to the control of the gray mold in various crop, brown spot, scab, rust, stalk break, downy mildew, peronospora tabacina, epidemic disease, damping off, balck shank, rust, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 20% Hexanaphthene flusulfamide suspending agent (autogamy), 100g/L cyazofamid suspending agent (commercial), 50% dimethomorph wetting powder (commercial), 25% metalaxyl wetting powder (350g/L Metalaxyl-M granule) (commercial), 35% Propamocarb aqua (commercial), 20% white urea cyanogen suspending agent (autogamy), 10% iprovalicarb suspending agent (autogamy).
Application Example eight Hexanaphthene flusulfamide and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
This experimental establishment is at Shaanxi Province's Weinan City, and the investigation downy mildew of garpe state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 Hexanaphthene flusulfamide and active component B and compositely prevent and treat the downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 22, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat downy mildew of garpe, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine Hexanaphthene flusulfamide and active component B and the composite control tomato blight test of pesticide effectiveness thereof
This test arrangement is in Xi'an City, Shanxi Province, and the investigation tomato blight state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 3 days, 7 days, 15 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 23 Hexanaphthene flusulfamide and active component B and the composite control tomato blight test of pesticide effectiveness thereof
As can be seen from Table 23, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat tomato blight, also have good preventive effect to graw mold of tomato, control efficiency is all better than the preventive effect of single dose simultaneously, and the preventive effect phase is long, in test scope of medication, target crop is had no adverse effects.
Application Example ten Hexanaphthene flusulfamide and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement is in Dongguan, Guangdong city, and the investigation peronophythora litchi state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 24 Hexanaphthene flusulfamide and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 24, Hexanaphthene flusulfamide and active component B and composite rear efficiency thereof prevent and treat peronophythora litchi, and control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 Hexanaphthene flusulfamide and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is in Jingyang County, Shaanxi Province, and the investigation cucumber downy mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 25 Hexanaphthene flusulfamide and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 25, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat cucumber downy mildew, also have good preventive effect to scab of cucumber, control efficiency is all better than the preventive effect of single dose simultaneously, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 Hexanaphthene flusulfamide and active component B and the composite control paddy rice damping off test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation paddy rice damping off state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 26 Hexanaphthene flusulfamide and active component B and the composite control paddy rice damping off test of pesticide effectiveness thereof
As can be seen from Table 26, Hexanaphthene flusulfamide and active component B and composite after can effectively prevent and treat paddy rice damping off, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 13 Hexanaphthene flusulfamide and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
This test arrangement is at Qinghai Province Men Yuanxian, and the investigation sclerotinia rot of colza state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 27 Hexanaphthene flusulfamide and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
As can be seen from Table 27, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat sclerotinia rot of colza, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 14 Hexanaphthene flusulfamide and active component B and the sick test of pesticide effectiveness of composite control pear scab thereof
This test arrangement is in Xianyang, Shanxi province city, and the investigation pear scab state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 28 Hexanaphthene flusulfamide and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 28, Hexanaphthene flusulfamide and active component B and composite rear efficiency thereof prevent and treat pear scab, and also have good preventive effect to pear tree rust, control efficiency is all better than the preventive effect of single dose simultaneously, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, Hexanaphthene flusulfamide and cyazofamid, dimethomorph, metalaxyl or its salt, Propamocarb, white urea cyanogen, the composite rear preventive effect to Common Diseases such as the gray mold in various crop, brown spot, scab, rust, stalk break, downy mildew, peronospora tabacina, epidemic disease, damping off, balck shank, rust of iprovalicarb all 95% with on excellent, in single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition containing Hexanaphthene flusulfamide, it is characterized in that: effective active composition is active components A and active component B, active components A and active component B weight ratio are 1 ︰ 70 ~ 70 ︰ 1, and described active components A is selected from Hexanaphthene flusulfamide, and active component B is dimethomorph.
2. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1.
3. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 2, is characterized in that: the weight ratio of Hexanaphthene flusulfamide and dimethomorph is 1 ︰ 10 ~ 20 ︰ 1.
4. the bactericidal composition containing Hexanaphthene flusulfamide according to any one of claims 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 4 is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, is characterized in that: described disease comprises gray mold, brown spot, scab, rust, stalk break, downy mildew, peronospora tabacina, epidemic disease, damping off, balck shank, rust.
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| CN201210319682.3A CN103651467B (en) | 2012-08-31 | 2012-08-31 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
| CN201510274504.7A CN104886064B (en) | 2012-08-31 | 2012-08-31 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
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| CN107006475A (en) * | 2016-08-25 | 2017-08-04 | 上海贯发海洋生物科技有限公司 | A kind of microbicide compositions of sour iodine containing oligomerization and its application |
| CN107027755A (en) * | 2017-03-08 | 2017-08-11 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and zoxamide |
| CN106900711A (en) * | 2017-03-08 | 2017-06-30 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and M 9834 |
| CN106973900A (en) * | 2017-03-10 | 2017-07-25 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and Metalaxyl-M |
| CN106922672A (en) * | 2017-03-10 | 2017-07-07 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and fluopyram |
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| EP0298196A1 (en) * | 1987-03-13 | 1989-01-11 | Ishihara Sangyo Kaisha, Ltd. | Imidazole compounds and biocidal compositions comprising the same |
| CN101720764A (en) * | 2008-10-13 | 2010-06-09 | 中国农业大学 | New application of N-(2-trifluoromethyl-4-chlorphenyl)-alpha-oxocyclohexyl sulfamide as sterilizing agent |
| CN102027957A (en) * | 2010-12-30 | 2011-04-27 | 陕西美邦农药有限公司 | Cyazofamid-containing bactericidal composition |
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| US2553771A (en) * | 1948-09-23 | 1951-05-22 | Standard Oil Dev Co | Method of preparing n-trichloromethylthioimides |
| CH351791A (en) * | 1957-10-26 | 1961-01-31 | Merck Ag E | Fungicidal agent |
| EP0313512B1 (en) * | 1987-08-21 | 1992-11-25 | Ciba-Geigy Ag | Benzothiadiazoles and their use in processes and compositions against plant diseases |
| CN100486961C (en) * | 2005-07-20 | 2009-05-13 | 中国农业大学 | 2-keto naphthene sulfamide, its preparing method and use as germicide |
| CN101653118B (en) * | 2009-07-31 | 2012-12-12 | 深圳诺普信农化股份有限公司 | Compound synergistic bactericidal composition |
| CN101642118A (en) * | 2009-09-08 | 2010-02-10 | 深圳诺普信农化股份有限公司 | Composition for plant protection |
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| EP0298196A1 (en) * | 1987-03-13 | 1989-01-11 | Ishihara Sangyo Kaisha, Ltd. | Imidazole compounds and biocidal compositions comprising the same |
| CN101720764A (en) * | 2008-10-13 | 2010-06-09 | 中国农业大学 | New application of N-(2-trifluoromethyl-4-chlorphenyl)-alpha-oxocyclohexyl sulfamide as sterilizing agent |
| CN102027957A (en) * | 2010-12-30 | 2011-04-27 | 陕西美邦农药有限公司 | Cyazofamid-containing bactericidal composition |
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