CN104285963A - High-efficiency bactericidal composition containing cyclohexylflusulfamide - Google Patents
High-efficiency bactericidal composition containing cyclohexylflusulfamide Download PDFInfo
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Abstract
The invention discloses a high-efficiency bactericidal composition containing cyclohexylflusulfamide. The bactericidal composition contains an active ingredient A and an active ingredient B, wherein the active ingredient A is selected from cyclohexylflusulfamide; the active ingredient B is selected from any one of the following compounds: flusilazole, epoxiconazole, myclobutanil, tetraconazole, flutriafol and tricyclazole; the weight ratio of the active ingredient A to the active ingredient B is (1 to 30)-(80 to 1). The composition has higher activity on various diseases of various crops, has obvious synergistic effects, expands the bactericidal spectrum and has the characteristics of small dosage, rain wash resistance and obvious synergistic effects.
Description
The application is divisional application, and original application is the patent application " a kind of efficient bactericidal composite containing Hexanaphthene flusulfamide " of Shaanxi Meibang Pesticide Co., Ltd., and the application number of original application is ︰ 201210290305.1, and original application day is 2012.08.15.
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of efficient bactericidal composite in crop pest containing Hexanaphthene flusulfamide.
Technical background
Hexanaphthene flusulfamide chemical name: N-(2-trifluoromethyl-4-chlorophenyl)-a-oxocyclohexyl sulfonamide.It has stronger prevention, treatment and osmotically active, and has higher lasting effect.Show through field test results, Hexanaphthene flusulfamide can prevent and treat gray mold, sclerotinia rot of colza, Cucumber Target Leaf Spot and scab effectively.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find Hexanaphthene flusulfamide and Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole mutually composite, there is good synergistic effect within the specific limits, and about Hexanaphthene flusulfamide and Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole relevant composite, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind of to there is the efficient bactericidal composite containing Hexanaphthene flusulfamide that synergistic function, use cost are low, preventive effect is good.
The present invention is achieved through the following technical solutions:
A kind of efficient bactericidal composite containing Hexanaphthene flusulfamide, containing active components A and active component B, active components A and active component B weight ratio are 1: 30 ~ 80: 1, described active components A is selected from Hexanaphthene flusulfamide, and active component B is selected from the one in Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole; The preferred weight ratio being preferably active components A and active component B is 1 ︰ 20 ~ 60 ︰ 1; The weight ratio being more preferably Hexanaphthene flusulfamide and Flusilazole is 1: 5 ~ 30: 1, the weight ratio of Hexanaphthene flusulfamide and epoxiconazole is 1: 10 ~ 20: 1, the weight ratio of Hexanaphthene flusulfamide and nitrile bacterium azoles is 1: 5 ~ 30: 1, the weight ratio of Hexanaphthene flusulfamide and tetraconazole is 1: 5 ~ 30: 1, the weight ratio of Hexanaphthene flusulfamide and Flutriafol is 1: 10 ~ 20: 1, and the weight ratio of Hexanaphthene flusulfamide and tricyclazole is 1: 10 ~ 20: 1; The weight ratio most preferably being Hexanaphthene flusulfamide and Flusilazole is 1: 1 ~ 14: 1, the weight ratio of Hexanaphthene flusulfamide and epoxiconazole is 1: 4 ~ 14: 1, the weight ratio of Hexanaphthene flusulfamide and nitrile bacterium azoles is 1: 1 ~ 19: 1, the weight ratio of Hexanaphthene flusulfamide and tetraconazole is 1: 1 ~ 19: 1, the weight ratio of Hexanaphthene flusulfamide and Flutriafol is 1 ︰ 4 ~ 9 ︰ 1, and the weight ratio of Hexanaphthene flusulfamide and tricyclazole is 1 ︰ 4 ~ 9 ︰ 1.
The described efficient bactericidal composite containing Hexanaphthene flusulfamide, composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
The described efficient bactericidal composite containing Hexanaphthene flusulfamide is for preventing and treating the disease of crop; Described crop comprises cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease comprises powdery mildew, spot defoliation, gray mold, brown spot, scab, stalk break, leaf spot, rust, glume blight, rust, damping off, eyeprint disease, graywall, smut, moire disease, rice blast, anthracnose, banded sclerotial blight, brown rot, rice blast, head blight, bakanae disease.
In bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
The bactericidal composition of invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing, then adds surfactant as one or more in dispersant, wetting agent, binding agent, defoamer etc. by active component with liquid flux or solid carrier.According to different dosage form, in preparation, stabilizing agent known in those skilled in the art, antifreeze etc. can also be contained.
Composition comprises following component and content when making wetting powder: active components A 0.5% ~ 80%, active component B 0.5% ~ 60%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 0.5% ~ 80%, active component B 0.5% ~ 60%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as powdery mildew, spot defoliation, gray mold, brown spot, scab, stalk break, leaf spot, rust, glume blight, rust, damping off, eyeprint disease, graywall, smut, moire disease, rice blast, anthracnose, banded sclerotial blight, brown rot, rice blast, head blight, bakanae disease have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 15 wetting powder
By Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1,2,3.
The each component of table 1 embodiment 1 ~ 5 and content
The each component of table 2 embodiment 6 ~ 10 and content
The each component of table 3 embodiment 11 ~ 15 and content
Embodiment 16 ~ 30 water dispersible granules
Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 4,5,6.
The each component of table 4 embodiment 16 ~ 20 and content
The each component of table 5 embodiment 21 ~ 25 and content
The each component of table 6 embodiment 26 ~ 30 and content
Embodiment 31 ~ 45 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add Hexanaphthene flusulfamide, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 7,8,9.
The each component of table 7 embodiment 31 ~ 35 and content
The each component of table 8 embodiment 36 ~ 40 and content
The each component of table 9 embodiment 41 ~ 45 and content
Embodiment 46 ~ 55 aqueous emulsion
Hexanaphthene flusulfamide, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 10,11.
The each component of table 10 embodiment 46 ~ 50 and content
The each component of table 11 embodiment 51 ~ 55 and content
Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole in table 1 ~ 11 are exchanged, can novel formulation be obtained.
Embodiment 56 ~ 60 microemulsion
Hexanaphthene flusulfamide, active component B are dissolved in and are equipped with in the homogenizer of solvent, by emulsifier, antifreeze (can add and can not add), defoamer, join above-mentioned solution is housed homogenizer in, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 12.
The each component of table 12 embodiment 56 ~ 60 and content
Embodiment 61 ~ 64 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add Hexanaphthene flusulfamide, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained Hexanaphthene flusulfamide suspending agent, then by active component B, emulsifier, solvent and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 13.
The each component of table 13 embodiment 61 ~ 64 and content
Embodiment 65 ~ 68 microcapsule suspending agent
By Hexanaphthene flusulfamide, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 14.
The each component of table 14 embodiment 65 ~ 68 and content
Embodiment 69 ~ 72 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add Hexanaphthene flusulfamide, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 15.
The each component of table 15 embodiment 69 ~ 72 and content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carry out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) converts logarithm value (x) to, try to achieve virulence regression equation (y=a+bx) with method of least squares, and calculate the EC of often kind of medicament thus
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is Hexanaphthene flusulfamide;
B is selected from the one in Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole.
Application Example two:
For examination disease: pear scab, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination Hexanaphthene flusulfamide and Flusilazole different ratio mixture.
Toxicity test result
Table 16 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to pear scab of Flusilazole
As shown in Table 16, the proportioning of Hexanaphthene flusulfamide and the composite control pear scab of Flusilazole is when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and Flusilazole is 1: 5 ~ 30: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and Flusilazole is 30 ︰ 1,25 ︰ 1,20 ︰ 1,15 ︰ 1,14 ︰ 1,13 ︰ 1,12 ︰ 1,11 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 5, when wherein Hexanaphthene flusulfamide and Flusilazole weight ratio are 8:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: alternaria leaf spot of apple, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and epoxiconazole raw drug and the two different ratio mixture
Toxicity test result
Table 17 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to alternaria leaf spot of apple of epoxiconazole
As shown in Table 17, the proportioning of Hexanaphthene flusulfamide and the composite control alternaria leaf spot of apple of epoxiconazole is when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and epoxiconazole is at 1 ︰ 10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and epoxiconazole is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 10, when wherein Hexanaphthene flusulfamide and epoxiconazole weight ratio are 5:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: powdery mildew of cucumber, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and bulk myclobutanil and the two different ratio mixture.
Toxicity test result
Table 18 Hexanaphthene flusulfamide and myclobutanil compositional are to the toxicity test analysis of results table of powdery mildew of cucumber
As shown in Table 18, Hexanaphthene flusulfamide and myclobutanil compositional prevent and treat the proportioning of powdery mildew of cucumber when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and nitrile bacterium azoles is 1: 5 ~ 30: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and nitrile bacterium azoles is 30 ︰ 1,25 ︰ 1,20 ︰ 1,19 ︰ 1,18 ︰ 1,17 ︰ 1,16 ︰ 1,15 ︰ 1,14 ︰ 1,13 ︰ 1,12 ︰ 1,11 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,1 ︰ 1,1 ︰ 5, when wherein Hexanaphthene flusulfamide and nitrile bacterium azoles weight ratio are 11:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: powdery mildew of strawberry, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of tetraconazole and the two different ratio mixture.
Toxicity test result
Table 19 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to powdery mildew of strawberry of tetraconazole
As shown in Table 19, the proportioning of Hexanaphthene flusulfamide and the composite control powdery mildew of strawberry of tetraconazole is when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and tetraconazole is 1: 5 ~ 30: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and tetraconazole is 30 ︰ 1,25 ︰ 1,20 ︰ 1,19 ︰ 1,18 ︰ 1,17 ︰ 1,16 ︰ 1,15 ︰ 1,14 ︰ 1,13 ︰ 1,12 ︰ 1,11 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,1 ︰ 5, when wherein Hexanaphthene flusulfamide and tetraconazole weight ratio are 12:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: wheat rust, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and the former medicine of Flutriafol and the two different ratio mixture.
Table 20 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to wheat rust of Flutriafol
As shown in Table 20, Hexanaphthene flusulfamide and the composite proportioning of preventing and treating wheat rust of Flutriafol are when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and Flutriafol is in 1:10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and Flutriafol is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 10, when wherein Hexanaphthene flusulfamide and Flutriafol weight ratio are 3:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For examination disease: rice blast, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination Hexanaphthene flusulfamide and Mensurating Tricyclazole Technical and the two different ratio mixture.
Table 21 Hexanaphthene flusulfamide and the composite toxicity test analysis of results table to rice blast of tricyclazole
As shown in Table 21, the proportioning of Hexanaphthene flusulfamide and the composite control rice blast of tricyclazole is when 1 ︰ 30 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 30 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of Hexanaphthene flusulfamide and tricyclazole is in 1:10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing through applicant the proportioning finding Hexanaphthene flusulfamide and tricyclazole is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 10, when wherein Hexanaphthene flusulfamide and tricyclazole weight ratio are 2:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: Hexanaphthene flusulfamide and active component B composite after have obvious synergistic effect to the control of the powdery mildew in various crop, spot defoliation, gray mold, brown spot, scab, stalk break, leaf spot, rust, glume blight, rust, damping off, eyeprint disease, graywall, smut, moire disease, rice blast, anthracnose, banded sclerotial blight, brown rot, rice blast, head blight, bakanae disease, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 20% Hexanaphthene flusulfamide suspending agent (autogamy), 10% Flusilazole aqueous emulsion (commercial), 12.5% epoxiconazole suspension concentrate (commercial), 12% nitrile bacterium azoles missible oil (commercial), 4% tetraconazole aqueous emulsion (commercial), 12.5% Flutriafol suspending agent (commercial), 20% tricyclazole suspending agent (commercial).
Application Example eight Hexanaphthene flusulfamide and active component B and composite control graw mold of tomato thereof are imitated and are tested
This experimental establishment is in Xi'an City, Shanxi Province, and the investigation graw mold of tomato state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 Hexanaphthene flusulfamide and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 22, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat graw mold of tomato, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine Hexanaphthene flusulfamide and active component B and compositely prevent and treat the cercospora leaf spot of sugar beet test of pesticide effectiveness
This test arrangement is in Xi'an City, Shanxi Province, and the investigation cercospora leaf spot of sugar beet state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 3 days, 7 days, 15 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 23 Hexanaphthene flusulfamide and active component B and compositely prevent and treat the cercospora leaf spot of sugar beet test of pesticide effectiveness
As can be seen from Table 23, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat cercospora leaf spot of sugar beet, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten Hexanaphthene flusulfamide and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Xianyang, Shanxi province city, and the investigation pear scab state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 24 Hexanaphthene flusulfamide and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 24, Hexanaphthene flusulfamide and active component B and composite rear efficiency thereof prevent and treat pear scab, and control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 Hexanaphthene flusulfamide and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation rice blast state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 25 Hexanaphthene flusulfamide and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 25, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat rice blast, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 Hexanaphthene flusulfamide and active component B and compositely prevent and treat the sigatoka test of pesticide effectiveness
This experimental establishment is in Nanning, and the investigation sigatoka state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 26 Hexanaphthene flusulfamide and active component B and compositely prevent and treat the sigatoka test of pesticide effectiveness
As can be seen from Table 26, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat sigatoka, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 13 Hexanaphthene flusulfamide and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City, and the investigation grape powdery mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 27 Hexanaphthene flusulfamide and active component B and the composite control grape powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 27, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat grape powdery mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 14 Hexanaphthene flusulfamide and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation sclerotinia rot of colza state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 28 Hexanaphthene flusulfamide and active component B and the composite control sclerotinia rot of colza test of pesticide effectiveness thereof
As can be seen from Table 28, Hexanaphthene flusulfamide and active component B and composite after effectively can prevent and treat sclerotinia rot of colza, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, Hexanaphthene flusulfamide and Flusilazole, epoxiconazole, nitrile bacterium azoles, tetraconazole, Flutriafol, tricyclazole is composite rear to the powdery mildew in various crop, spot defoliation, gray mold, brown spot, scab, stalk break, leaf spot, rust, glume blight, rust, damping off, eyeprint is sick, graywall, smut, moire disease, rice blast, anthracnose, banded sclerotial blight, brown rot, rice blast, head blight, the preventive effect of the Common Diseases such as bakanae disease all 95% with on excellent, in single dose preventive effect, synergistic effect is obvious.
| Consult people | Zhao Jiao | Liang Xiaojuan |
| Mark | 9.6 | 9.8 |
Claims (6)
1. the efficient bactericidal composite containing Hexanaphthene flusulfamide, it is characterized in that: effective active composition is active components A and active component B, active components A and active component B weight ratio are 1: 30 ~ 80: 1, and described active components A is Hexanaphthene flusulfamide, and active component B is nitrile bacterium azoles.
2. the efficient bactericidal composite containing Hexanaphthene flusulfamide according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1: 20 ~ 60: 1.
3. the efficient bactericidal composite containing Hexanaphthene flusulfamide according to claim 2, is characterized in that:
The weight ratio of Hexanaphthene flusulfamide and nitrile bacterium azoles is 1: 5 ~ 30: 1.
4. the efficient bactericidal composite containing Hexanaphthene flusulfamide according to any one of claims 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the efficient bactericidal composite containing Hexanaphthene flusulfamide according to claim 4 is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, is characterized in that: described disease comprises powdery mildew, spot defoliation, gray mold, brown spot, scab, stalk break, leaf spot, rust, glume blight, rust, damping off, eyeprint disease, graywall, smut, moire disease, rice blast, anthracnose, banded sclerotial blight, brown rot, head blight, bakanae disease.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106889075A (en) * | 2017-03-10 | 2017-06-27 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and RH-7592 |
| CN106900717A (en) * | 2017-03-10 | 2017-06-30 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and Fenarimol |
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| US5571829A (en) * | 1994-11-16 | 1996-11-05 | Rohm And Haas Company | Synergistic insecticidal compositions |
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| US5571829A (en) * | 1994-11-16 | 1996-11-05 | Rohm And Haas Company | Synergistic insecticidal compositions |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106889075A (en) * | 2017-03-10 | 2017-06-27 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and RH-7592 |
| CN106900717A (en) * | 2017-03-10 | 2017-06-30 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application containing Hexanaphthene flusulfamide and Fenarimol |
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Address after: 715500 Pucheng high tech Industrial Development Zone, Weinan, Shaanxi Patentee after: Shaanxi Mei Bang Pharmaceutical Group Limited by Share Ltd Address before: 715500 Shaanxi Pucheng Weinan County agricultural base industrial park Patentee before: Shaanxi Meibang Pesticide Co., Ltd. |