CN104336024A - Bactericidal composition containing fluorothiazolepyrithylone and amides - Google Patents
Bactericidal composition containing fluorothiazolepyrithylone and amides Download PDFInfo
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- CN104336024A CN104336024A CN201310344484.7A CN201310344484A CN104336024A CN 104336024 A CN104336024 A CN 104336024A CN 201310344484 A CN201310344484 A CN 201310344484A CN 104336024 A CN104336024 A CN 104336024A
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Abstract
The invention discloses a bactericidal composition containing fluorothiazolepyrithylone and amides. The bactericidal composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is fluorothiazolepyrithylone; the active ingredient B is selected from any one of the following compounds: fluopicolide, mandipropamid, flumorph and tiadinil; the weight ratio of the active ingredient A to the active ingredient B is (1 to 80)-(80 to 1). The composition has higher activity towards various diseases of various crops, has obvious synergistic effects, expands the bactericidal spectrum and has the characteristics of small dosage, rain wash resistance and obvious synergistic effects.
Description
Technical field
The invention belongs to technical field of pesticide, relate to the application of bactericidal composition in crop pest of a kind of fluorine-containing thiazole pyrrole ethyl ketone and amide-type.
Technical background
Fluorine thiazole pyrrole ethyl ketone is a kind of novel bactericide, remarkable to the preventive effect of downy mildew, epidemic disease.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find fluorine thiazole pyrrole ethyl ketone and fluopicolide, mandipropamid, flumorph, tiadinil mutually composite, there is good synergistic effect within the specific limits, and about fluorine thiazole pyrrole ethyl ketone and fluopicolide, mandipropamid, flumorph, tiadinil relevant composite, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind of bactericidal composition with synergistic function, use cost is low, preventive effect is good fluorine-containing thiazole pyrrole ethyl ketone and amide-type.
The present invention is achieved through the following technical solutions:
The bactericidal composition of a kind of fluorine-containing thiazole pyrrole ethyl ketone and amide-type, containing active components A and active component B, active components A and active component B weight ratio are 1: 80 ~ 80: 1, described active components A is selected from fluorine thiazole pyrrole ethyl ketone, and active component B is selected from the one in fluopicolide, mandipropamid, flumorph, tiadinil; The weight ratio being preferably active components A and active component B is 1 ︰ 60 ~ 60 ︰ 1; The weight ratio being more preferably fluorine thiazole pyrrole ethyl ketone and fluopicolide is 1: 20 ~ 20: 1, the weight ratio of fluorine thiazole pyrrole ethyl ketone and mandipropamid is 1: 20 ~ 20: 1, the weight ratio of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 20 ~ 20: 1, and the weight ratio of fluorine thiazole pyrrole ethyl ketone and tiadinil is 1: 20 ~ 20: 1; The weight ratio being more preferably fluorine thiazole pyrrole ethyl ketone and fluopicolide is 1: 9 ~ 9: 1, the weight ratio of fluorine thiazole pyrrole ethyl ketone and mandipropamid is 1: 9 ~ 9: 1, the weight ratio of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 9 ~ 9: 1, and the weight ratio of fluorine thiazole pyrrole ethyl ketone and tiadinil is 1: 9 ~ 9: 1.
Bactericidal composition of the present invention, acceptable formulation in any sterilization can be processed on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, oil-suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, can also make granule, seed coat agent, suspension seed-coating agent.
Described fluorine-containing thiazole pyrrole ethyl ketone and the bactericidal composition of amide-type are for preventing and treating the disease of crop; Described crop is cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease is downy mildew, epidemic disease, peronospora tabacina, damping off, rice blast, brown spot, bacterial leaf-blight, banded sclerotial blight, powdery mildew, rust.
In bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Liquids in general preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active component, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, disintegrant, defoamer etc.According to different dosage form, can also containing antifreeze known in those skilled in the art etc. in preparation.
Composition comprises following component and content when making wetting powder: active components A 0.5% ~ 80%, active component B 0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 0.5% ~ 80%, active component B 0.5% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent or oil-suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as downy mildew, epidemic disease, peronospora tabacina, damping off, rice blast, brown spot, bacterial leaf-blight, banded sclerotial blight, powdery mildew, rust etc. have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 14 wetting powder
By fluorine thiazole pyrrole ethyl ketone, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1.
The each component of table 1 embodiment 1 ~ 14 and content
Embodiment 15 ~ 28 water dispersible granules
Fluorine thiazole pyrrole ethyl ketone, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 15 ~ 28 and content
Embodiment 29 ~ 42 suspending agent or oil-suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add fluorine thiazole pyrrole ethyl ketone, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water or vegetable oil are supplied, and can obtain suspending agent of the present invention or oil-suspending agent product, specifically in table 3.
The each component of table 3 embodiment 29 ~ 42 and content
Embodiment 43 ~ 52 aqueous emulsion
Fluorine thiazole pyrrole ethyl ketone, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 4.
The each component of table 4 embodiment 43 ~ 52 and content
Fluopicolide, mandipropamid, flumorph, tiadinil in table 1 ~ 4 are exchanged, can novel formulation be obtained.
Embodiment 53 ~ 55 microemulsion
Fluorine thiazole pyrrole ethyl ketone, active component B are dissolved in and are equipped with in the homogenizer of solvent, by emulsifier, antifreeze (can add and can not add), defoamer, join above-mentioned solution is housed homogenizer in, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 5.
The each component of table 5 embodiment 53 ~ 55 and content
Embodiment 56 ~ 62 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add fluorine thiazole pyrrole ethyl ketone, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained fluorine thiazole pyrrole ethyl ketone suspending agent, then by active component B, emulsifier, solvent and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 6.
The each component of table 6 embodiment 56 ~ 62 and content
Embodiment 63 ~ 65 microcapsule suspending agent
By fluorine thiazole pyrrole ethyl ketone, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
The each component of table 7 embodiment 63 ~ 65 and content
Embodiment 66 ~ 68 microcapsule suspension--suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add fluorine thiazole pyrrole ethyl ketone, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 8.
The each component of table 8 embodiment 66 ~ 68 and content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is fluorine thiazole pyrrole ethyl ketone;
B is selected from the one in fluopicolide, mandipropamid, flumorph or tiadinil.
Application Example two:
For examination disease: cucumber downy mildew, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination fluorine thiazole pyrrole ethyl ketone and fluopicolide different ratio mixture.
Toxicity test result
Table 9 fluorine thiazole pyrrole ethyl ketone and the composite toxicity test analysis of results table to cucumber downy mildew of fluopicolide
As shown in Table 9, the proportioning of fluorine thiazole pyrrole ethyl ketone and the composite control cucumber downy mildew of fluopicolide is when 1 ︰ 80 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of fluorine thiazole pyrrole ethyl ketone and fluopicolide is 1: 20 ~ 20: 1, synergistic effect is more outstanding, synergy ratio is all more than 2.30, when the weight ratio of fluorine thiazole pyrrole ethyl ketone and fluopicolide is 1: 9 ~ 9: 1, synergistic effect is the most outstanding, and synergy ratio is all more than 2.40.Testing through applicant the proportioning finding fluorine thiazole pyrrole ethyl ketone and fluopicolide is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein fluorine thiazole pyrrole ethyl ketone and fluopicolide weight ratio are 3:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: potato late blight, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine thiazole pyrrole ethyl ketone and the former medicine of mandipropamid and the two different ratio mixture.
Toxicity test result
Table 10 fluorine thiazole pyrrole ethyl ketone and the composite toxicity test analysis of results table to potato late blight of mandipropamid
As shown in Table 10, fluorine thiazole pyrrole ethyl ketone and the composite proportioning of preventing and treating potato late blight of mandipropamid are when 1 ︰ 80 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of fluorine thiazole pyrrole ethyl ketone and mandipropamid is 1: 20 ~ 20: 1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, when the weight ratio of fluorine thiazole pyrrole ethyl ketone and mandipropamid is 1: 9 ~ 9: 1, synergistic effect is the most outstanding, and synergy ratio is all more than 2.40.Testing through applicant the proportioning finding fluorine thiazole pyrrole ethyl ketone and mandipropamid is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein fluorine thiazole pyrrole ethyl ketone and mandipropamid weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: cucumber downy mildew, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine thiazole pyrrole ethyl ketone and the former medicine of flumorph and the two different ratio mixture.
Toxicity test result
Table 11 fluorine thiazole pyrrole ethyl ketone and the composite toxicity test analysis of results table to cucumber downy mildew of flumorph
As shown in Table 11, the proportioning of fluorine thiazole pyrrole ethyl ketone and the composite control cucumber downy mildew of flumorph is when 1 ︰ 80 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 20 ~ 20: 1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, when the weight ratio of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 9 ~ 9: 1, synergistic effect is the most outstanding, and synergy ratio is all more than 2.35.Testing through applicant the proportioning finding fluorine thiazole pyrrole ethyl ketone and flumorph is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein fluorine thiazole pyrrole ethyl ketone and flumorph weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: early blight of tomato, test medicine provides by Shaanxi Meibang Pesticide Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination fluorine thiazole pyrrole ethyl ketone and the former medicine of tiadinil and the two different ratio mixture.
Toxicity test result
Table 12 fluorine thiazole pyrrole ethyl ketone and the composite toxicity test analysis of results table to early blight of tomato of tiadinil
As shown in Table 12, fluorine thiazole pyrrole ethyl ketone and the composite proportioning of preventing and treating early blight of tomato of tiadinil are when 1 ︰ 80 ~ 80 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 80 ~ 80 ︰ 1 scope all shows synergistic effect, the proportioning of fluorine thiazole pyrrole ethyl ketone and tiadinil is 1: 20 ~ 20: 1, synergistic effect is more outstanding, synergy ratio is all more than 2.25, when the weight ratio of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 9 ~ 9: 1, synergistic effect is the most outstanding, and synergy ratio is all more than 2.40.Testing through applicant the proportioning finding fluorine thiazole pyrrole ethyl ketone and tiadinil is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein fluorine thiazole pyrrole ethyl ketone and tiadinil weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: fluorine thiazole pyrrole ethyl ketone and active component B composite after have obvious synergistic effect to the control of the downy mildew in various crop, epidemic disease, peronospora tabacina, damping off, rice blast, brown spot, bacterial leaf-blight, banded sclerotial blight, powdery mildew, rust, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, contrast medicament 10% fluorine thiazole pyrrole ethyl ketone oil-suspending agent (autogamy), 20% fluopicolide suspending agent (commercial), 23.4% mandipropamid suspending agent (commercial), 20% flumorph wetting powder (commercial), 20% tiadinil suspending agent (autogamy).
Application Example hexafluoro thiazole pyrrole ethyl ketone and active component B and compositely prevent and treat the potato late blight test of pesticide effectiveness
This experimental establishment is at Shaanxi Province's Weinan City, and the investigation potato late blight state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 13 fluorine thiazole pyrrole ethyl ketone and active component B and compositely prevent and treat the potato late blight test of pesticide effectiveness
As can be seen from Table 13, fluorine thiazole pyrrole ethyl ketone and active component B and composite after effectively can prevent and treat potato late blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven fluorine thiazole pyrrole ethyl ketone and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is in Jingyang County, Shaanxi Province, and the investigation cucumber downy mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 3 days, 7 days, 15 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 14 fluorine thiazole pyrrole ethyl ketone and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 14, fluorine thiazole pyrrole ethyl ketone and active component B and composite after effectively can prevent and treat cucumber downy mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, has no adverse effects in test scope of medication to target crop.
Application Example octafluoro thiazole pyrrole ethyl ketone and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation rice blast state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 15 fluorine thiazole pyrrole ethyl ketone and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 15, fluorine thiazole pyrrole ethyl ketone and active component B and composite rear efficiency thereof prevent and treat rice blast, and control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to rice sheath blight disease, drug effect is up to more than 96% simultaneously.
Application Example nine fluorine thiazole pyrrole ethyl ketone and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement is in Zengcheng City of Guangdong Province, and the investigation peronophythora litchi state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 16 fluorine thiazole pyrrole ethyl ketone and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 16, fluorine thiazole pyrrole ethyl ketone and active component B and composite after effectively can prevent and treat peronophythora litchi, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten fluorine thiazole pyrrole ethyl ketone and active component B and compositely prevent and treat the early blight of tomato test of pesticide effectiveness
This test arrangement is in Xi'an City, Shanxi Province, and the investigation early blight of tomato state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 17 fluorine thiazole pyrrole ethyl ketone and active component B and compositely prevent and treat the early blight of tomato test of pesticide effectiveness
As can be seen from Table 17, fluorine thiazole pyrrole ethyl ketone and active component B and composite after effectively can prevent and treat early blight of tomato, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 fluorine thiazole pyrrole ethyl ketone and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
This test arrangement is in Xi'an City, Shanxi Province, and the investigation cucumber damping off state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 fluorine thiazole pyrrole ethyl ketone and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
As can be seen from Table 18, fluorine thiazole pyrrole ethyl ketone and active component B and composite after can effectively prevent and treat cucumber damping off, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, fluorine thiazole pyrrole ethyl ketone and fluopicolide, mandipropamid, flumorph, the composite rear preventive effect to Common Diseases such as the downy mildew in various crop, epidemic disease, peronospora tabacina, damping off, rice blast, brown spot, bacterial leaf-blight, banded sclerotial blight, powdery mildew, rust of tiadinil are all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition of a fluorine-containing thiazole pyrrole ethyl ketone and amide-type, effective active composition is active components A and active component B, it is characterized in that: the weight ratio of active components A and active component B is 1: 80 ~ 80: 1, described active components A is selected from fluorine thiazole pyrrole ethyl ketone, and active component B is selected from the one in fluopicolide, mandipropamid, flumorph or tiadinil.
2. the bactericidal composition of fluorine-containing thiazole pyrrole ethyl ketone according to claim 1 and amide-type, is characterized in that: the weight ratio of active components A and active component B is 1: 60 ~ 60: 1.
3. the bactericidal composition of fluorine-containing thiazole pyrrole ethyl ketone according to claim 2 and amide-type, is characterized in that:
The weight ratio of fluorine thiazole pyrrole ethyl ketone and fluopicolide is 1: 20 ~ 20: 1;
The weight ratio of fluorine thiazole pyrrole ethyl ketone and mandipropamid is 1: 20 ~ 20: 1;
The weight ratio of fluorine thiazole pyrrole ethyl ketone and flumorph is 1: 20 ~ 20: 1;
The weight ratio of fluorine thiazole pyrrole ethyl ketone and tiadinil is 1: 20 ~ 20: 1.
4. the fluorine-containing thiazole pyrrole ethyl ketone according to any one of claims 1 to 3 and the bactericidal composition of amide-type, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, oil-suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent.
5. the bactericidal composition of fluorine-containing thiazole pyrrole ethyl ketone according to claim 4 and amide-type is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, is characterized in that: described disease is downy mildew, epidemic disease, peronospora tabacina, damping off, rice blast, brown spot, bacterial leaf-blight, banded sclerotial blight, powdery mildew or rust.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105052945A (en) * | 2015-09-09 | 2015-11-18 | 江苏省绿盾植保农药实验有限公司 | Fungicide composition containing fluopicolide and oxathiapiprolin |
| CN106818779A (en) * | 2017-02-15 | 2017-06-13 | 海南省植物保护总站（海南省农药检定所） | A kind of bactericidal composition comprising fluorine thiazole pyrrole ethyl ketone |
| CN116058377A (en) * | 2023-02-13 | 2023-05-05 | 海利尔药业集团股份有限公司 | Use of bactericidal composition containing mandipropamid and oxazomet for preventing and treating grape downy mildew |
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| CN101888843A (en) * | 2006-07-27 | 2010-11-17 | 杜邦公司 | Fungicidal azocyclic amides |
| CN101969781A (en) * | 2007-10-23 | 2011-02-09 | 杜邦公司 | Fungicidal compounds and mixtures |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101888843A (en) * | 2006-07-27 | 2010-11-17 | 杜邦公司 | Fungicidal azocyclic amides |
| CN101969781A (en) * | 2007-10-23 | 2011-02-09 | 杜邦公司 | Fungicidal compounds and mixtures |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105052945A (en) * | 2015-09-09 | 2015-11-18 | 江苏省绿盾植保农药实验有限公司 | Fungicide composition containing fluopicolide and oxathiapiprolin |
| CN106818779A (en) * | 2017-02-15 | 2017-06-13 | 海南省植物保护总站（海南省农药检定所） | A kind of bactericidal composition comprising fluorine thiazole pyrrole ethyl ketone |
| CN116058377A (en) * | 2023-02-13 | 2023-05-05 | 海利尔药业集团股份有限公司 | Use of bactericidal composition containing mandipropamid and oxazomet for preventing and treating grape downy mildew |
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