CN103891739B - A kind of bactericidal composition containing azoles mepanipyrim and amide-type - Google Patents
A kind of bactericidal composition containing azoles mepanipyrim and amide-type Download PDFInfo
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Abstract
The invention discloses a kind of bactericidal composition containing azoles mepanipyrim and amide-type, effective active composition is active components A and active component B, active components A is selected from azoles mepanipyrim, active component B is selected from any one compound following: fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax or ring propionyl bacterium amine, and the weight ratio of active components A and active component B is 1: 70 ~ 70: 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious synergistic effect, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition in crop pest containing azoles mepanipyrim and amide-type.
Technical background
Azoles mepanipyrim (ametoctradin) obtains interim registration in China, and azoles mepanipyrim is brand-new triazolo pyrimidine series bactericidal agent, for the downy mildew of prevention and control cucumber and grape crop.
In the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find by azoles mepanipyrim and fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax or ring propionyl bacterium amine mutually composite, there is good synergistic effect within the specific limits, and about azoles mepanipyrim relevant composite to fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax or ring propionyl bacterium amine, there is not yet relevant report at home and abroad at present.
Summary of the invention
The object of the invention is to propose a kind ofly have that synergistic function, use cost are low, preventive effect is good containing the bactericidal composition of azoles mepanipyrim and amide-type.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition containing azoles mepanipyrim and amide-type, containing active components A and active component B, active components A and active component B weight ratio are 1: 70 ~ 70: 1, described active components A is selected from azoles mepanipyrim, and active component B is selected from the one in fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax or ring propionyl bacterium amine; The weight ratio being preferably active components A and active component B is 1 ︰ 50 ~ 50 ︰ 1; The weight ratio being more preferably azoles mepanipyrim and fluopicolide is 1: 10 ~ 20: 1, the weight ratio of azoles mepanipyrim and mandipropamid or flumorph or tiadinil or pyrrole metsulfovax or ring propionyl bacterium amine is 1: 20 ~ 10: 1, and the weight ratio of azoles mepanipyrim and zoxamide is 1: 20 ~ 20: 1.
Bactericidal composition of the present invention, can be processed into acceptable formulation in any sterilization on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
The described bactericidal composition containing azoles mepanipyrim and amide-type is for preventing and treating the disease of crop; Described crop is cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; Described disease is downy mildew, peronospora tabacina, epidemic disease, rust, gray mold, powdery mildew, scab, stalk break, rice blast, banded sclerotial blight, brown spot or leaf blight.
In bactericidal composition of the present invention, the content of active component depends on amount of application when being used alone, and also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, simultaneously also relevant with target disease.In usual composition, the weight percentage of active component is 1% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Liquids in general preparation contains the active substance of by weight 1% ~ 60%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active component, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, disintegrant, defoamer etc.According to different dosage form, can also containing antifreeze known in those skilled in the art etc. in preparation.
Composition comprises following component and content when making wetting powder: active components A 0.5% ~ 70%, active component B0.5% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
Composition comprises following component and content when making water dispersible granules: active components A 0.5% ~ 70%, active component B0.5% ~ 70%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following component and content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) pesticide usage amount reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) fungicidal spectrum is expanded, to multiple diseases as downy mildew, peronospora tabacina, epidemic disease, rust, gray mold, powdery mildew, scab, stalk break, rice blast, banded sclerotial blight, brown spot, leaf blight etc. have greater activity.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 16 wetting powder
By azoles mepanipyrim, active component B, dispersant, wetting agent, filler mixing, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, namely can be made into wetting powder product of the present invention.Specifically in table 1.
The each component of table 1 embodiment 1 ~ 16 and content
Embodiment 17 ~ 32 water dispersible granules
Azoles mepanipyrim, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 17 ~ 32 and content
Embodiment 33 ~ 48 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add azoles mepanipyrim, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 33 ~ 48 and content
Embodiment 49 ~ 57 aqueous emulsion
Azoles mepanipyrim, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, obtained aqueous emulsion product of the present invention.Specifically in table 4.
The each component of table 4 embodiment 49 ~ 57 and content
Embodiment 58 ~ 66 microemulsion
Azoles mepanipyrim, active component B are dissolved in and are equipped with in the homogenizer of solvent, by emulsifier, antifreeze (can add and can not add), defoamer, join above-mentioned solution is housed homogenizer in, surplus deionized water gives strong mixing and homogenize after supplying, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically in table 5.
The each component of table 5 embodiment 58 ~ 66 and content
Fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax, ring propionyl bacterium amine in table 1 ~ 5 are exchanged, can novel formulation be obtained.
Embodiment 67 ~ 69 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add azoles mepanipyrim, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained azoles mepanipyrim suspending agent, then by active component B, emulsifier, solvent and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, obtained suspension emulsion product of the present invention.Specifically in table 6.
The each component of table 6 embodiment 67 ~ 69 and content
Embodiment 70 ~ 72 microcapsule suspending agent
By azoles mepanipyrim, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, defoamer, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
The each component of table 7 embodiment 70 ~ 72 and content
Embodiment 73 ~ 75 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add azoles mepanipyrim, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, makes the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition.Specifically in table 8.
The each component of table 8 embodiment 73 ~ 75 and content
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is azoles mepanipyrim;
B is selected from the one in fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax, ring propionyl bacterium amine.
Application Example two:
For examination disease: cucumber downy mildew, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination azoles mepanipyrim and fluopicolide different ratio mixture.
Toxicity test result
Table 9 azoles mepanipyrim and the composite toxicity test analysis of results table to cucumber downy mildew of fluopicolide
As shown in Table 9, the proportioning of azoles mepanipyrim and the composite control cucumber downy mildew of fluopicolide is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and fluopicolide is 1: 10 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Testing through applicant the proportioning finding azoles mepanipyrim and fluopicolide is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10, when wherein azoles mepanipyrim and fluopicolide weight ratio are 3:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example three:
For examination disease: potato late blight, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of mandipropamid and the two different ratio mixture.
Toxicity test result
Table 10 azoles mepanipyrim and the composite toxicity test analysis of results table to potato late blight of mandipropamid
As shown in Table 10, the proportioning of azoles mepanipyrim and the composite control potato late blight of mandipropamid is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and mandipropamid is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding azoles mepanipyrim and mandipropamid is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and mandipropamid weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example four:
For examination disease: cucumber downy mildew, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of flumorph and the two different ratio mixture.
Toxicity test result
Table 11 azoles mepanipyrim and the composite toxicity test analysis of results table to cucumber downy mildew of flumorph
As shown in Table 11, the proportioning of azoles mepanipyrim and the composite control cucumber downy mildew of flumorph is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and flumorph is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding azoles mepanipyrim and flumorph is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and flumorph weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example five:
For examination disease: rice blast, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of tiadinil and the two different ratio mixture.
Toxicity test result
Table 12 azoles mepanipyrim and the composite toxicity test analysis of results table to rice blast of tiadinil
As shown in Table 12, the proportioning of azoles mepanipyrim and the composite control rice blast of tiadinil is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and tiadinil is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding azoles mepanipyrim and tiadinil is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and tiadinil weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example six:
For examination disease: downy mildew of garpe, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of zoxamide and the two different ratio mixture.
Toxicity test result
Table 13 azoles mepanipyrim and the composite toxicity test analysis of results table to downy mildew of garpe of zoxamide
As shown in Table 13, azoles mepanipyrim and the composite proportioning of preventing and treating downy mildew of garpe of zoxamide are when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and zoxamide is 1: 20 ~ 20: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding azoles mepanipyrim and zoxamide is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and zoxamide weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example seven:
For examination disease: pear scab, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of pyrrole metsulfovax and the two different ratio mixture.
Toxicity test result
Table 14 azoles mepanipyrim and the composite toxicity test analysis of results table to pear scab of pyrrole metsulfovax
As shown in Table 14, the proportioning of azoles mepanipyrim and the composite control pear scab of pyrrole metsulfovax is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and pyrrole metsulfovax is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.25.Testing through applicant the proportioning finding azoles mepanipyrim and pyrrole metsulfovax is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and pyrrole metsulfovax weight ratio are 2:3, synergy ratio is maximum, and synergistic effect is the most obvious.
Application Example eight:
For examination disease: rice blast, test medicine provides by Shanxi Thompson Biological Technology Co., Ltd., experimental scheme: through effective inhibition concentration scope of preliminary experiment determination azoles mepanipyrim and the former medicine of ring propionyl bacterium amine and the two different ratio mixture.
Toxicity test result
Table 15 azoles mepanipyrim and the composite toxicity test analysis of results table to rice blast of ring propionyl bacterium amine
As shown in Table 15, the proportioning of azoles mepanipyrim and the composite control rice blast of ring propionyl bacterium amine is when 1 ︰ 70 ~ 70 ︰ 1, synergy ratio SR is all greater than 1.5, both explanations mixture in 1 ︰ 70 ~ 70 ︰ 1 scope all shows synergistic effect, the proportioning of azoles mepanipyrim and ring propionyl bacterium amine is 1: 20 ~ 10: 1, synergistic effect is more outstanding, and synergy ratio is all more than 2.30.Testing through applicant the proportioning finding azoles mepanipyrim and ring propionyl bacterium amine is 10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰ 20, when wherein azoles mepanipyrim and ring propionyl bacterium amine weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.
Through test find: azoles mepanipyrim and active component B composite after have obvious synergistic effect to the control of the downy mildew in various crop, peronospora tabacina, epidemic disease, rust, gray mold, powdery mildew, scab, stalk break, rice blast, banded sclerotial blight, brown spot, leaf blight, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., provided, contrast medicament 20% azoles mepanipyrim suspending agent (autogamy), 20% fluopicolide suspending agent (autogamy), 23.4% mandipropamid suspending agent (commercial), 20% flumorph wetting powder (commercial), 20% tiadinil suspending agent (autogamy), 24% zoxamide suspending agent (autogamy), 15% pyrrole metsulfovax suspending agent (autogamy), 20% ring propionyl bacterium amine suspending agent (autogamy).
Application Example nine azoles mepanipyrim and active component B and the composite control potato late blight test of pesticide effectiveness thereof
This experimental establishment is at Shaanxi Province's Weinan City, and the investigation potato late blight state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 16 azoles mepanipyrim and active component B and the composite control potato late blight test of pesticide effectiveness thereof
As can be seen from Table 16, azoles mepanipyrim and active component B and composite after effectively can prevent and treat potato late blight, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten azoles mepanipyrim and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement is in Jingyang County, Shaanxi Province, and the investigation cucumber downy mildew state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 3 days, 7 days, 15 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 17 azoles mepanipyrim and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 17, azoles mepanipyrim and active component B and composite after effectively can prevent and treat cucumber downy mildew, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long, has no adverse effects in test scope of medication to target crop.Also have good preventive effect to gray mold of cucumber, powdery mildew, stalk break, drug effect is up to more than 96% simultaneously.
Application Example 11 azoles mepanipyrim and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and the investigation rice blast state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 18 azoles mepanipyrim and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 18, azoles mepanipyrim and active component B and composite rear efficiency thereof prevent and treat rice blast, and control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to rice sheath blight disease, drug effect is up to more than 96% simultaneously.
Application Example ten diazole mepanipyrim and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Weinan City, and the investigation grape grey mould state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 19 azoles mepanipyrim and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
As can be seen from Table 19, azoles mepanipyrim and active component B and composite after effectively can prevent and treat grape grey mould, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to grape powdery mildew, downy mildew, drug effect is up to more than 96% simultaneously.
Application Example ten triazole mepanipyrim and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
This test arrangement is in Xi'an City, Shanxi Province, and the investigation graw mold of tomato state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 20 azoles mepanipyrim and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 20, azoles mepanipyrim and active component B and composite after effectively can prevent and treat graw mold of tomato, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.Also have good preventive effect to tomato blight, drug effect is up to more than 96% simultaneously.
Application Example ten tetrazolium mepanipyrim and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement is in Zengcheng City of Guangdong Province, and the investigation peronophythora litchi state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 21 azoles mepanipyrim and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 21, azoles mepanipyrim and active component B and composite after effectively can prevent and treat peronophythora litchi, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten pentazole mepanipyrim and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Xianyang, Shanxi province city, and the investigation pear scab state of an illness before medicine, in the first time dispenser of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after second time dispenser 7 days, 14 days, 30 days, investigate disease index respectively and calculate preventive effect.Experimental result is as follows:
Table 22 azoles mepanipyrim and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 22, azoles mepanipyrim and active component B and composite after effectively can prevent and treat pear scab, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, the composite rear preventive effect to Common Diseases such as the downy mildew in various crop, peronospora tabacina, epidemic disease, rust, gray mold, powdery mildew, scab, stalk break, rice blast, banded sclerotial blight, brown spot or leaf blights of fluopicolide, mandipropamid, flumorph, tiadinil, zoxamide, pyrrole metsulfovax or ring propionyl bacterium amine is all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. one kind contains the bactericidal composition of azoles mepanipyrim and amide-type, effective active composition is active components A and active component B, it is characterized in that: the weight ratio of active components A and active component B is 1: 70 ~ 70: 1, and described active components A is azoles mepanipyrim, and active component B is mandipropamid.
2. the bactericidal composition containing azoles mepanipyrim and amide-type according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1: 50 ~ 50: 1.
3. the bactericidal composition containing azoles mepanipyrim and amide-type according to claim 2, is characterized in that:
The weight ratio of azoles mepanipyrim and mandipropamid is 1: 20 ~ 10: 1.
4. the bactericidal composition containing azoles mepanipyrim and amide-type according to any one of claims 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent.
5. the bactericidal composition containing azoles mepanipyrim and amide-type according to claim 4 is for preventing and treating the purposes of crop pest.
6. purposes according to claim 5, is characterized in that: described disease is downy mildew, peronospora tabacina, epidemic disease, rust, gray mold, powdery mildew, scab, stalk break, rice blast, banded sclerotial blight, brown spot or leaf blight.
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