CN102027957A - Cyazofamid-containing bactericidal composition - Google Patents
Cyazofamid-containing bactericidal composition Download PDFInfo
- Publication number
- CN102027957A CN102027957A CN2010106159333A CN201010615933A CN102027957A CN 102027957 A CN102027957 A CN 102027957A CN 2010106159333 A CN2010106159333 A CN 2010106159333A CN 201010615933 A CN201010615933 A CN 201010615933A CN 102027957 A CN102027957 A CN 102027957A
- Authority
- CN
- China
- Prior art keywords
- cyanogen frost
- frost azoles
- azoles
- bactericidal composition
- iprodione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides a cyazofamid-containing bactericidal composition, which comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is cyazofamid; and the active ingredient B is selected from one of carbendazim, ethylicin and iprodione. The bactericidal composition comprises the following components in percentage by weight: 1 to 40 percent of cyazofamid serving as the active ingredient A, 1 to 80 percent of active ingredient B and the balance of aid and excipient. The cyazofamid-containing bactericidal composition is used for preventing and controlling various diseases such as downy mildew, epidemic disease, alternaria leaf spot, anthracnose, cladosporium cucumerinum, botrytis, powdery mildew and leaf spot and has remarkable synergistic effect.
Description
Technical field
The invention belongs to technical field of pesticide, be specifically related to a kind of bactericidal composition that contains cyanogen frost azoles, be used to prevent and treat crop downy mildew, eqpidemic disease, spot defoliation, anthracnose, scab, gray mold, powdery mildew, leaf spot.
Technical background
Cyanogen frost azoles (cyazofamid), molecular formula is C
13H
13ClN
4O
2S, chemical name is: 4-chloro-2-cyano group-N, N-dimethyl-5-p-methylphenyl imidazoles-1-sulfonamide; Cyanogen azoles flusulfamide, structural formula is:
The sulphaguanidine azoles fungicide.Plasmodiophora brassica bacteria to Oomycete fungi such as phytophthora, downy mildew, false downy mildew, pythium spp and Plasmodiophoromycetes has very high biologically active.Mechanism of action is mitochondrial cytochrome b c in the blocking-up Oomycete germ body
1The electronics transmission of complex comes the supply of interfering energy, and its binding site is the Q of enzyme
1The center does not have cross tolerance with other bactericide.It may be owing to the sensitivity difference of target enzyme to medicament causes that its height to pathogen is selected activity.Use in the field has high control efficiency to late blight and downy mildew, and using dosage as handling potato late blight with the concentration of 50～100mg/L outstanding control efficiency is arranged, and the medication phase is flexible, the lasting period is long than low 2～38 times of other bactericide.Downy mildew with same concentration processing grape, cucumber, muskmelon also has fabulous control efficiency.This medicament can prolong the plant growth time, and makes increasing both production and income.Be used for tomato the effect that improves quality is arranged.Access times are no more than 4 times, and using method is a foliar spray.Under the concentration of treatment that exceeds 4 times of actual amount, do not see the poisoning report.Just at the expanding prevention object, comprise pimento eqpidemic disease, ground rot of water melon, the sick downy mildew of Da Bai, onion downy mildew and other diseases at present.
The agent of cyanogen frost azoles list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
Cyanogen frost azoles of the present invention and carbendazim, S-Ethyl ethylthio sulfonate or iprodione preparation can be used for preventing and treating the multiple diseases on fruit tree, vegetables, cereal crops, the economic crops; crop is had excellent protection and therapeutic action, and field trial has showed extremely strong antibiotic and bactericidal activity.
The present invention realizes in the following manner:
A kind of bactericidal composition that contains cyanogen frost azoles is characterized in that this bactericidal composition contains 1～40% effective constituents A cyanogen frost azoles and 1～80% active ingredient B.
The described bactericidal composition that contains cyanogen frost azoles contains 1～30% effective constituents A cyanogen frost azoles and 5～60% active ingredient B.
The described bactericidal composition that contains cyanogen frost azoles is characterized in that: the percentage by weight of cyanogen frost azoles and carbendazim is 5～20: 10～50.
The described bactericidal composition that contains cyanogen frost azoles is characterized in that: the percentage by weight of cyanogen frost azoles and S-Ethyl ethylthio sulfonate is 5～20: 10～40.
The described bactericidal composition that contains cyanogen frost azoles is characterized in that: the percentage by weight of cyanogen frost azoles and iprodione is 5～20: 10～50.
The described bactericidal composition that contains cyanogen frost azoles, effective constituents A are cyanogen frost azoles, and active ingredient B is a kind of in carbendazim, S-Ethyl ethylthio sulfonate, the iprodione.
The described bactericidal composition that contains cyanogen frost azoles is characterized in that active ingredient adds auxiliary agent and excipients can be made into wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion or aqueous emulsion.
Described auxiliary agent and excipient are selected from: one or more of dispersant, wetting agent, disintegrant, solvent, emulsifier, antifreeze, defoamer, thickener, solid packing or deionized water.
When making wetting powder, composition comprises following constituent content: cyanogen frost azoles 1～40%, effective active composition B 1～80%, dispersant 3～10%, wetting agent 2～10%, filler 8～93%.
Cyanogen frost azoles, effective active composition B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into present composition wetting powder product.
When making water dispersible granules, composition comprises following constituent content: cyanogen frost azoles 1～40%, effective active composition B 1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, filler 8～93%.
Cyanogen frost azoles, effective active composition B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes present composition water dispersible granules product.
Comprise following constituent content when composition is made suspending agent: cyanogen frost azoles 1～20%, active ingredient B 1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0～8%, stabilizing agent 0%～3%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, cyanogen frost azoles, adding active ingredient B, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes present composition suspending agent product.
Comprise following constituent content when composition is made suspension emulsion: cyanogen frost azoles 1～20%, effective active composition B 1～40%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of effective active composition B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the former medicine suspending agent of effective active composition B, then with the former medicine of cyanogen frost azoles, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make present composition suspension emulsion product.
Comprise following constituent content when composition is made microemulsion: cyanogen frost azoles 1～20%, effective active composition B 1～40%, emulsifier 10%～20%, solvent 1～25%, defoamer 0.1～0.5%,, antifreeze 1～5%, water add to 100%.
Emulsifier and water are mixed into water, and the former medicine that will be dissolved in then in the solvent under agitation adds water, makes present composition microemulsion product.
Comprise following constituent content when composition is made aqueous emulsion: cyanogen frost azoles 1～15%, effective active composition B 1～35%, emulsifier 5%～10%, solvent 0～30%, defoamer 0～1%, thickener 0.1～2%, antifreeze 1～8%, stabilizing agent 0～3%, water add to 100%.
The step that this cyanogen frost azoles and effective active composition B compound water emulsion preparation method comprise is: cyanogen frost azoles and effective active composition B are dissolved in obtain oil phase in the solvent; All the other components are mixed with water obtain water; Oil phase and water are made present composition aqueous emulsion product under shear conditions.
Described dispersant is selected from one or more in polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, the fatty acid glyceride APEO.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, DBSA, Nekal BX, wetting and penetrating agent F, alkylnaphthalene sulfonate, polyoxyethylene triphenylethylene phosphenylic acid salt, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, the sodium bicarbonate.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, the glycerine.
Described defoamer is selected from: silicone oil, silicone compound, C
10～20Saturated fat acid compounds, C
8～10In the aliphatic alcohols compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether), farming newborn 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), farming newborn 36# (phenethyl fluosite polyoxy ethyl ether), farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether), farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), in the AEO series (the pure APEO of fat) one or more.
Described solvent is selected from: N, dinethylformamide, 3-methyl cyclohexanol ketenes, N-octylpyrrolidone, N-pyrrolidones, toluene, propyl alcohol, cyclohexanone, acetone, methyl alcohol, ethanol, butanols, ethylene glycol monomethyl ether, butyl ether, ethyl acetate, vegetable oil, acetonitrile one or more.
Described stabilizing agent is selected from: one or more in BHT, triphenyl phosphite, epoxychloropropane, tributyl phosphate, triethanolamine, diethanol amine, the monoethanolamine.
Described preservative is selected from: one or more in benzoic acid, potassium sorbate, the Sodium Benzoate.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
It is remarkable that the described bactericidal composition that contains cyanogen frost azoles is used to prevent and treat spot defoliation, anthracnose, scab, eqpidemic disease, gray mold, powdery mildew, leaf spot multiple diseases effect, compares with single agent, has obvious synergistic effect.
The present invention has following advantage: 1. double action mechanism, germ are difficult for producing resistance; 2. synergistic effect is obvious, and indoor biological test result shows: cyanogen frost azoles and carbendazim, S-Ethyl ethylthio sulfonate or iprodione are composite by a certain percentage that crop pest is had the notable synergistic effect; 3. expansion fungicidal spectrum, cyanogen frost azoles and carbendazim, S-Ethyl ethylthio sulfonate or iprodione can be prevented and treated the multiple main disease on fruit tree, vegetables, the cereal crops, as downy mildew, eqpidemic disease, spot defoliation, anthracnose, scab, gray mold, powdery mildew, leaf spot multiple diseases; 4. genus environment friendly agricultural, cyanogen frost azoles, carbendazim, S-Ethyl ethylthio sulfonate, iprodione all belong to low-toxin farm chemicals, its complex preparation, high-efficiency low-toxicity to crop and Environmental security, helps the sustainable development of agricultural production.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 70% cyanogen frost azoles carbendazol wettable powder
Cyanogen frost azoles 20%, carbendazim 50%, lignosulfonates 6%, Nekal BX 6%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 70% cyanogen frost azoles carbendazol wettable powder.
Example 2 82% cyanogen frost azoles carbendazol wettable powder
Cyanogen frost azoles 2%, carbendazim 80%, polyoxyethylene carboxylate 7%, wetting and penetrating agent F5%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 82% cyanogen frost azoles carbendazol wettable powder.
Example 3 55% cyanogen frost azoles carbendazim water dispersing granule
Cyanogen frost azoles 5%, carbendazim 50%, silkworm excrement 6%, aryl phenol polyoxyethylene succinate sulfonate 7%, urea 0.8%, diatomite add to 100%, the mixed 55% cyanogen frost azoles carbendazim water dispersing granule that gets.
Example 4 70% cyanogen frost azoles carbendazim water dispersing granule
Cyanogen frost azoles 10%, carbendazim 60%, the phonetic formaldehyde condensation products sulphate 9% of alkylphenol-polyethenoxy, spaonin powder 7%, bentonite add to 100%, the mixed 70% cyanogen frost azoles carbendazim water dispersing granule that gets.
Example 5 30% cyanogen frost azoles carbendazim suspending agent
Cyanogen frost azoles 5%, carbendazim 25%, ester polyoxyethylene are phonetic 6%, lauryl sodium sulfate 4%, silicone oil 0.3%, xanthans 1.2%, glycerine 1.5%, deionized water add to 100%, mixed 30% cyanogen frost azoles carbendazim suspending agent.
Example 6 44% cyanogen frost azoles carbendazim suspending agent
Cyanogen frost azoles 4%, carbendazim 40%, alkyl benzene sulfonate calcium salt 7%, wetting and penetrating agent F 5%, silicone compound 0.2%, polyvinylpyrrolidone 1.4%, polyethylene glycol 1.5%, deionized water add to 100%, the mixed 44% cyanogen frost azoles carbendazim suspending agent that gets.
Example 7 20% cyanogen frost azoles carbendazim suspension emulsion
Cyanogen frost azoles 10%, carbendazim 10%, aliphatic amine polyoxyethylene are phonetic 6%, soapberry powder 4%, polyvinyl alcohol 1.1%, epoxychloropropane 0.6%, tween series 6%, ethylene glycol 2%, C
8～10Aliphatic alcohols 0.2%, water add to 100%, through the mixed 20% cyanogen frost azoles carbendazim suspension emulsion that gets.
Example 8 48% cyanogen frost azoles carbendazim suspension emulsion
Cyanogen frost azoles 3%, carbendazim 45%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, Nekal BX 5%, methylcellulose 1.5%, agricultural newborn 1600#5%, glycerine 1.2%, silicone compound 0.4%, water add to 100%, through the mixed 48% cyanogen frost azoles carbendazim suspension emulsion that gets.
Example 9 50% cyanogen frost azoles S-Ethyl ethylthio sulfonate wetting powder
Cyanogen frost azoles 10%, S-Ethyl ethylthio sulfonate 40%, polycarboxylate 8%, Nekal BX 6%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 50% cyanogen frost azoles S-Ethyl ethylthio sulfonate wetting powder.
Example 10 80% cyanogen frost azoles S-Ethyl ethylthio sulfonate wetting powder
Cyanogen frost azoles 20%, S-Ethyl ethylthio sulfonate 60%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, silkworm excrement 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 80% cyanogen frost azoles S-Ethyl ethylthio sulfonate wetting powder.
Example 11 45% cyanogen frost azoles S-Ethyl ethylthio sulfonate water dispersible granules
Cyanogen frost azoles 15%, S-Ethyl ethylthio sulfonate 30%, lignosulfonates 6%, wetting and penetrating agent F 4%, ammonium sulfate 0.9%, attapulgite add to 100%, the mixed 45% cyanogen frost azoles S-Ethyl ethylthio sulfonate water dispersible granules that gets.
Example 12 65% cyanogen frost azoles S-Ethyl ethylthio sulfonate water dispersible granules
Cyanogen frost azoles 5%, S-Ethyl ethylthio sulfonate 60%, naphthalene sulfonic acid-formaldehyde condensation product 8%, neopelex 7%, bentonite add to 100%, the mixed 65% cyanogen frost azoles S-Ethyl ethylthio sulfonate water dispersible granules that gets.
Example 13 30% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspending agent
Cyanogen frost azoles 20%, S-Ethyl ethylthio sulfonate 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, spaonin powder 4%, C
8～10Aliphatic alcohols 0.3%, polyvinylpyrrolidone 1.6%, polyethylene glycol 1.2%, deionized water add to 100%, the mixed 30% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspending agent that gets.
Example 14 36% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspending agent
Cyanogen frost azoles 12%, S-Ethyl ethylthio sulfonate 24%, polyoxyethylene carboxylate 6%, Nekal BX 5%, silicone compound 0.2%, gum Arabic 1.7%, glycerine 1.3%, deionized water add to 100%, the mixed 36% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspending agent that gets.
Example 15 25% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspension emulsion
Cyanogen frost azoles 5%, S-Ethyl ethylthio sulfonate 20%, polyoxyethylene carboxylate 6%, silkworm excrement 5%, silicone oil 0.5%, methylcellulose 1.6%, triphenyl phosphite 0.7%, Nongru-700 #4%, ethylene glycol 1.7%, water add to 100%, the aforementioned formula material is mixed, promptly make 25% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspension emulsion.
Example 16 50% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspension emulsion
Cyanogen frost azoles 40%, S-Ethyl ethylthio sulfonate 10%, lignosulfonates 6%, lauryl sodium sulfate 4%, silicone compound 0.4%, polyvinylpyrrolidone 1.2%, OP series 6%, propane diols 0.9%, water add to 100%, the aforementioned formula material is mixed, promptly make 50% cyanogen frost azoles S-Ethyl ethylthio sulfonate suspension emulsion.
Example 17 30% cyanogen frost azoles S-Ethyl ethylthio sulfonate microemulsion
Cyanogen frost azoles 10%, S-Ethyl ethylthio sulfonate 20%, toluene 9%, vegetable oil 7%, agricultural newborn 1600#7%, triphenyl phosphite 2%, glycerine 1.3%, C
8～10Aliphatic alcohols 0.2%, deionized water supplies 100%, makes 30% cyanogen frost azoles S-Ethyl ethylthio sulfonate microemulsion.
Example 18 45% cyanogen frost azoles S-Ethyl ethylthio sulfonate microemulsion
Cyanogen frost azoles 5%, S-Ethyl ethylthio sulfonate 40%, acetone 15%, tween series 4%, agricultural newborn 33#4%, ethylene glycol 1%, epoxychloropropane 1.5%, C
10～20Saturated fat acids 0.3%, deionized water supplies 100%, makes 45% cyanogen frost azoles S-Ethyl ethylthio sulfonate microemulsion.
Example 19 32% cyanogen frost azoles S-Ethyl ethylthio sulfonate aqueous emulsion
Cyanogen frost azoles 16%, S-Ethyl ethylthio sulfonate 16%, ethylene glycol monomethyl ether 5%, propyl alcohol 4%, ethyl acetate 5%, OP series phosphate 4%, agricultural newborn 34#6%, polyethylene glycol 1.8%, methylcellulose 1%, silicone compound 0.3%, deionized water supplies 100%, makes 32% cyanogen frost azoles S-Ethyl ethylthio sulfonate aqueous emulsion.
Example 20 48% cyanogen frost azoles S-Ethyl ethylthio sulfonate aqueous emulsion
Cyanogen frost azoles 16%, S-Ethyl ethylthio sulfonate 32%, vegetable oil 12%, cyclohexanone 4%, By series 3%, agricultural newborn 500#5%, ethylene glycol 2%, sodium phosphate trimer 1.2%, C
8～10Aliphatic alcohols 0.2%, deionized water supplies 100%, makes 48% cyanogen frost azoles S-Ethyl ethylthio sulfonate aqueous emulsion.
Example 21 63% cyanogen frost azoles iprodione wettable powder
Cyanogen frost azoles 3%, iprodione 60%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, wetting and penetrating agent F 4%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 63% cyanogen frost azoles iprodione wettable powder.
Example 22 80% cyanogen frost azoles iprodione wettable powder
Cyanogen frost azoles 30%, iprodione 50%, aryl phenol polyoxyethylene succinate sulfonate 7%, Nekal BX 6%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 80% cyanogen frost azoles iprodione wettable powder.
Example 23 66% cyanogen frost azoles iprodione water dispersible granules
Cyanogen frost azoles 6%, iprodione 60%, alkyl benzene sulfonate calcium salt 8%, neopelex 6%, bentonite add to 100%, the mixed 66% cyanogen frost azoles iprodione water dispersible granules that gets.
Example 24 80% cyanogen frost azoles iprodione water dispersible granules
Cyanogen frost azoles 5%, iprodione 75%, lignosulfonates 7%, soapberry powder 5%, ammonium sulfate 0.8%, kaolin add to 100%, the mixed 80% cyanogen frost azoles iprodione water dispersible granules that gets.
Example 25 33% cyanogen frost azoles iprodione suspending agent
Cyanogen frost azoles 3%, iprodione 30%, polyoxyethylene carboxylate 7%, spaonin powder 4%, C
8～10Aliphatic alcohols 0.2%, methylcellulose 1.3%, polyethylene glycol 1.5%, deionized water add to 100%, the mixed 33% cyanogen frost azoles iprodione suspending agent that gets.
Example 26 48% cyanogen frost azoles iprodione suspending agent
Cyanogen frost azoles 8%, iprodione 40%, aryl phenol polyoxyethylene succinate sulfonate 7%, wetting and penetrating agent F 5%, silicone compound 0.4%, polyvinylpyrrolidone 1.6%, ethylene glycol 1.4%, deionized water add to 100%, the mixed 48% cyanogen frost azoles iprodione suspending agent that gets.
Example 27 18% cyanogen frost azoles iprodione suspension emulsion
Cyanogen frost azoles 9%, iprodione 9%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, Nekal BX 6%, xanthans 1.2%, triethanolamine 1.2%, agricultural newborn 1600#7%, glycerine 3%, C
10～20Saturated fat acids 0.5%, water add to 100%, through the mixed 18% cyanogen frost azoles iprodione suspension emulsion that gets.
Example 28 42% cyanogen frost azoles iprodione suspension emulsion
Cyanogen frost azoles 7%, iprodione 35%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 6%, lauryl sodium sulfate 5%, methylcellulose 1.3%, agricultural newborn 34#5%, ethylene glycol 1.8%, silicone compound 0.3%, water add to 100%, through the mixed 42% cyanogen frost azoles iprodione suspension emulsion that gets.
Example 29 36% cyanogen frost azoles iprodione microemulsion
Cyanogen frost azoles 4%, iprodione 32%, toluene 6%, N-pyrrolidones 7%, Nongru-700 #8%, epoxychloropropane 1%, polyethylene glycol 1.9%, silicone compound 0.3%, deionized water supplies 100%, makes 36% cyanogen frost azoles iprodione microemulsion.
Example 30 42% cyanogen frost azoles iprodione microemulsion
Cyanogen frost azoles 7%, iprodione 35%, N, dinethylformamide 5%, toluene 9%, tween series 6%, glycerine 2.3%, tributyl phosphate 1.1%, C
8～10Aliphatic alcohols 0.4%, deionized water supplies 100%, makes 42% cyanogen frost azoles iprodione microemulsion.
Example 31 36% cyanogen frost azoles iprodione aqueous emulsion
Cyanogen frost azoles 6%, iprodione 30%, 3-methyl cyclohexanol ketenes 8%, ethyl acetate 6%, deionization farming breast 1600
#6%, agricultural newborn 34#3%, propane diols 2%, methylcellulose 1.5%, C
10～20Saturated fat acids 0.5%, deionized water supplies 100%, makes 36% cyanogen frost azoles iprodione aqueous emulsion.
Example 32 40% cyanogen frost azoles iprodione aqueous emulsion
Cyanogen frost azoles 20%, iprodione 20%, N-octylpyrrolidone 8%, toluene 9%, agricultural newborn 1600#3%, OP series phosphate 5%, glycerine 3%, sodium phosphate trimer 1.2%, silicone compound 0.2%, deionized water supplies 100%, makes 40% cyanogen frost azoles iprodione aqueous emulsion.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Cyanogen frost azoles and active component B (B be selected from carbendazim, S-Ethyl ethylthio sulfonate, the iprodione a kind of) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component cyanogen frost azoles and B (carbendazim, S-Ethyl ethylthio sulfonate, iprodione) shared ratio in combination;
A is a cyanogen frost azoles;
B is a kind of in carbendazim, S-Ethyl ethylthio sulfonate, the iprodione.
Implementation of an application example two: cyanogen frost azoles and carbendazim are composite to the downy mildew of garpe Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining cyanogen frost azoles, carbendazim active compound and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 cyanogen frost azoles, carbendazim and composite toxicity test analysis of results table thereof to downy mildew of garpe
As shown in Table 1, cyanogen frost azoles, carbendazim are to the EC of downy mildew of garpe
50Be respectively 5.61mg/L and 45.24mg/L.Cyanogen frost azoles and carbendazim proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that both proportionings were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, synergy ratio SR maximum when cyanogen frost azoles and carbendazim weight ratio are 1: 10 wherein, synergistic effect is the most obvious.
Implementation of an application example three
Cyanogen frost azoles and S-Ethyl ethylthio sulfonate are composite to the cucumber downy mildew Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining cyanogen frost azoles, the former medicine of S-Ethyl ethylthio sulfonate and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 cyanogen frost azoles, S-Ethyl ethylthio sulfonate and composite toxicity test analysis of results table thereof to cucumber downy mildew
As shown in Table 2, cyanogen frost azoles, S-Ethyl ethylthio sulfonate are to the EC of cucumber downy mildew
50Be respectively 6.03mg/L and 12.65mg/L.Cyanogen frost azoles and S-Ethyl ethylthio sulfonate proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that both were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 4: 1 to 1: 8, synergistic effect is more obviously outstanding, synergy ratio SR maximum when cyanogen frost azoles and S-Ethyl ethylthio sulfonate weight ratio are 1: 2 wherein, synergistic effect is the most obvious.
Implementation of an application example four
Cyanogen frost azoles and iprodione are to the early blight of tomato Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining cyanogen frost azoles, the former medicine of iprodione and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 cyanogen frost azoles, iprodione and composite toxicity test analysis of results table thereof to early blight of tomato
As shown in Table 3, cyanogen frost azoles, iprodione are to the EC of early blight of tomato
50Be respectively 5.07mg/L and 41.06mg/L.Cyanogen frost azoles and iprodione proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that both were mixed in the scope at 40: 1 to 1: 80 shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, synergy ratio SR maximum when cyanogen frost azoles and iprodione weight ratio are 1: 10 wherein, synergistic effect is the most obvious.
Application Example five cyanogen frost azoles and the carbendazim and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Jingyang County, Xianyang, Shanxi province city, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 100 grams per liter cyanogen frost azole suspending agent (commercial), 50% carbendazol wettable powder (commercial).
The investigation downy mildew of garpe state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the third time.Experimental result is as follows:
Table 4 cyanogen frost azoles carbendazim is prevented and treated the downy mildew of garpe test of pesticide effectiveness
As shown in Table 4, cyanogen frost azoles and carbendazim are composite remarkable to the downy mildew of garpe control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period.In this experimental drug weight range, to grape safety, have no adverse effects, preparation of the present invention has good control efficiency to downy mildew of garpe.
Application Example six cyanogen frost azoles and the S-Ethyl ethylthio sulfonate and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Dali County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 100 grams per liter cyanogen frost azole suspending agent (commercial), 80% S-Ethyl ethylthio sulfonate missible oil (commercial).
The preceding investigation of medicine cucumber downy mildew disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
The table 5 cyanogen frost azoles S-Ethyl ethylthio sulfonate control cucumber downy mildew test of pesticide effectiveness
As shown in Table 5, cyanogen frost azoles and S-Ethyl ethylthio sulfonate are composite remarkable to the cucumber downy mildew control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period.In this experimental drug weight range, to cucumber safety, have no adverse effects, preparation of the present invention has good control efficiency to cucumber downy mildew.
Application Example seven cyanogen frost azoles and the iprodione and the composite early blight of tomato test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at the Xian City, Shanxi Province Changan District, and test medicine is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 100 grams per liter cyanogen frost azole suspending agent (commercial), 50% iprodione wettable powder (commercial).
The investigation early blight of tomato state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 6 cyanogen frost azoles iprodione is prevented and treated the early blight of tomato test of pesticide effectiveness
As shown in Table 6, cyanogen frost azoles and iprodione are remarkable to the early blight of tomato control efficiency, compare with single agent, have preventive effect height, long, residual little advantage of lasting period.In this experimental drug weight range, to tomato safety, have no adverse effects, preparation of the present invention has good control efficiency to early blight of tomato.
Claims (8)
1. bactericidal composition that contains cyanogen frost azoles is characterized in that this bactericidal composition contains 1～40% cyanogen frost azoles and 1～80% active ingredient B.
2. according to the described bactericidal composition that contains cyanogen frost azoles of claim 1, it is characterized in that: active ingredient B is selected from a kind of in carbendazim, S-Ethyl ethylthio sulfonate or the iprodione.
3. according to the described bactericidal composition that contains cyanogen frost azoles of claim 1, it is characterized in that: the percentage by weight of active components A cyanogen frost azoles and active component B is 1～30%: 5～60%.
4. according to the described bactericidal composition that contains cyanogen frost azoles of claim 3, it is characterized in that: the percentage by weight of cyanogen frost azoles and carbendazim is 5～20: 10～50.
5. according to the described bactericidal composition that contains cyanogen frost azoles of claim 3, it is characterized in that: the percentage by weight of cyanogen frost azoles and S-Ethyl ethylthio sulfonate is 5～20: 10～40.
6. according to the described bactericidal composition that contains cyanogen frost azoles of claim 3, it is characterized in that: the percentage by weight of cyanogen frost azoles and iprodione is 5～20: 10～50.
7. according to the described bactericidal composition that contains cyanogen frost azoles of claim 1, it is characterized in that: cyanogen frost azoles and active ingredient B composition can be made into wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion.
8. the described bactericidal composition that contains cyanogen frost azoles of claim 1 is used to prevent and treat the disease on fruit tree, vegetables and the cereal crops: downy mildew, eqpidemic disease, spot defoliation, anthracnose, scab, gray mold, powdery mildew, leaf spot.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106159333A CN102027957A (en) | 2010-12-30 | 2010-12-30 | Cyazofamid-containing bactericidal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106159333A CN102027957A (en) | 2010-12-30 | 2010-12-30 | Cyazofamid-containing bactericidal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102027957A true CN102027957A (en) | 2011-04-27 |
Family
ID=43881838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010106159333A Pending CN102027957A (en) | 2010-12-30 | 2010-12-30 | Cyazofamid-containing bactericidal composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102027957A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103651467A (en) * | 2012-08-31 | 2014-03-26 | 陕西美邦农药有限公司 | Cyclohexyl flusulfamide-containing bactericidal composition |
| WO2014170764A1 (en) | 2013-04-16 | 2014-10-23 | Upl Limited | Fungicidal composition |
| CN104920405A (en) * | 2015-06-09 | 2015-09-23 | 柳州市天姿园艺有限公司 | Composition for controlling leaf spot disease of cymbidium goeringii |
| CN104920462A (en) * | 2015-06-09 | 2015-09-23 | 柳州市天姿园艺有限公司 | Composition for controlling leaf spot disease of paphiopedilum |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101755799A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Cyazofamid-containing bactericidal composition |
-
2010
- 2010-12-30 CN CN2010106159333A patent/CN102027957A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101755799A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Cyazofamid-containing bactericidal composition |
Non-Patent Citations (1)
| Title |
|---|
| 龙友华: "10%氰霜唑悬浮剂防治番茄晚疫病的田间应用研究", 《安徽农学通报》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103651467A (en) * | 2012-08-31 | 2014-03-26 | 陕西美邦农药有限公司 | Cyclohexyl flusulfamide-containing bactericidal composition |
| CN103651467B (en) * | 2012-08-31 | 2015-09-09 | 陕西美邦农药有限公司 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
| WO2014170764A1 (en) | 2013-04-16 | 2014-10-23 | Upl Limited | Fungicidal composition |
| CN105101799A (en) * | 2013-04-16 | 2015-11-25 | Upl有限公司 | Fungicidal composition |
| EP2943067A4 (en) * | 2013-04-16 | 2016-06-01 | Upl Ltd | Fungicidal composition |
| CN105101799B (en) * | 2013-04-16 | 2018-01-23 | Upl 有限公司 | Fungicidal composition |
| CN104920405A (en) * | 2015-06-09 | 2015-09-23 | 柳州市天姿园艺有限公司 | Composition for controlling leaf spot disease of cymbidium goeringii |
| CN104920462A (en) * | 2015-06-09 | 2015-09-23 | 柳州市天姿园艺有限公司 | Composition for controlling leaf spot disease of paphiopedilum |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102210308A (en) | Pesticide composite containing picoxystrobin and triazole compound | |
| CN102100233A (en) | Sterilization composition containing benziothiazolinone and hexaconazole | |
| CN102150680B (en) | Bactericidal composition containing iprodione and triazole compound | |
| CN102113487A (en) | Bactericidal composition containing cyazofamid and methoxy acrylate compound | |
| CN102027957A (en) | Cyazofamid-containing bactericidal composition | |
| CN102239863A (en) | Bactericidal composition containing picoxystrobin and thiocarbamates | |
| CN102057927A (en) | Bactericidal composition containing captan and triazole compounds | |
| CN102197820A (en) | Bactericidal composition containing picoxystrobin and benzimidazoles | |
| CN102007914A (en) | Triflumizole-containing synergistic sterilization composition | |
| CN101889573B (en) | Sterilizing composite with imazaril and azoxystrobin | |
| CN101779635B (en) | Bactericidal composite containing phenol cycloheximide and difenoconazole | |
| CN102057913A (en) | Bactericidal composition containing triflumizole and triazole compound | |
| CN102150683B (en) | Fenbuconazole-containing synergic sterilization composition | |
| CN101755792B (en) | Fungicidal composition containing kresoxim methyl and thiophanate methyl | |
| CN102067861A (en) | Fenbuconazole-containing bactericidal composition | |
| CN101779656B (en) | Bactericidal composite containing flusilazole and kresoxim-methyl | |
| CN102067862A (en) | Ipconazole-containing bactericidal composition | |
| CN102057935B (en) | Bactericidal composition containing imidazole | |
| CN102017951B (en) | Germicide composition containing cyproconazole and chlorothalonil | |
| CN102204544A (en) | Picoxystrobin-containing synergic bactericidal composition | |
| CN101697720B (en) | Bactericide composition containing ethirimol and kresoxim | |
| CN101779649A (en) | Bactericidal composite containing phenol cycloheximide and thiophanate-methyl | |
| CN101861863B (en) | Sterilization compound containing imazalil and kresoxim-methyl | |
| CN101971816B (en) | Sterilizing composition containing cyproconazole and dithianon | |
| CN101779630B (en) | Bactericidal composite containing phenol cycloheximide and dithianon |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 715500 Weinan City, Shaanxi province Pucheng County agricultural base industrial park Applicant after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shaanxi Meibang Pesticide Co., Ltd. |
|
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20110427 |