CN102239863A - Bactericidal composition containing picoxystrobin and thiocarbamates - Google Patents
Bactericidal composition containing picoxystrobin and thiocarbamates Download PDFInfo
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- CN102239863A CN102239863A CN201110082950XA CN201110082950A CN102239863A CN 102239863 A CN102239863 A CN 102239863A CN 201110082950X A CN201110082950X A CN 201110082950XA CN 201110082950 A CN201110082950 A CN 201110082950A CN 102239863 A CN102239863 A CN 102239863A
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- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a bactericidal composition containing picoxystrobin and thiocarbamates. The bactericidal composition comprise an active component A and an active component B, wherein the active component A is selected from picoxystrobin, and the active component B is one selected from the following bactericides: mancozeb, propineb, zineb and metiram; and a weight percentage of the active component A to the active component B is 1-60%:1-80%. The composition of the invention can prevent a plurality of crop diseases, such as downy mildew, leaf spot, rust, epidemic disease, venturia inaequalis, alternaria leaf spot, anthracnose, powdery mildew, physalosporapiricola, scab disease and leaf blight, has obvious synergism, and is quite safe to crops. Besides, the bactericidal composition has advantages of resistance to rain wash, lasting drug effect and small drug dose.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application that contains the bactericidal composition of ZEN 90160 and thiocarbamates.
Background technology
ZEN 90160, English common name: picoxystrobin, molecular formula: C
18H
16F
3NO
4, chemical name: (E)-3-methoxy-2-[2-[6-(trifluoromethyl)-2-pyridine oxygen methyl] phenyl] methyl acrylate.ZEN 90160 is the mitochondrial respiratory inhibitor, promptly shifts by electronics between cytochrome b and c1 and suppresses mitochondrial breathing.Control is effective to the bacterial strain that 14-demethylation enzyme inhibitor, benzamides, dicarboxylic dihydrazides amine and benzimidazole produce resistance.。
Summary of the invention
The long-term use of the single agent of ZEN 90160 may bring degradation problem under resistance generation, the drug effect.The present invention proposes a kind of bactericidal composition that contains ZEN 90160 and thiocarbamates, it is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～60%: 1～80%, described active component A is a ZEN 90160, and active component B is selected from a kind of in mancozeb, Propineb, zineb or the Carbatene.
The described bactericidal composition that contains ZEN 90160 is characterized in that: the percentage by weight of A, two kinds of active components of B is 3～50%: 5～70%.
The described bactericidal composition that contains ZEN 90160 is characterized in that: the percentage by weight of ZEN 90160 and mancozeb is 5～30%: 10～60%.
The described bactericidal composition that contains ZEN 90160 is characterized in that: the percentage by weight of ZEN 90160 and Propineb is 5～30%: 10～60%.
The described bactericidal composition that contains ZEN 90160 is characterized in that: the percentage by weight of ZEN 90160 and zineb is 5～30%: 10～60%.
The described bactericidal composition that contains ZEN 90160 is characterized in that: the percentage by weight of ZEN 90160 and Carbatene is 5～30%: 10～60%.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 0.5～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the defoamer one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described disintegrant is selected from: one or more in sodium bicarbonate, sodium carbonate, bentonite, urea, ammonium sulfate, the aluminium chloride.
Described wetting agent is selected from: lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, tea are withered, in the silkworm excrement, soapberry powder one or more.
Described thickener is selected from: one or more in xanthans, gelatin, gum Arabic, melon glue, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, diethylene glycol (DEG), triethylene glycol, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether), farming newborn 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), farming newborn 36# (phenethyl fluosite polyoxy ethyl ether), farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether), farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), in the AEO series (the pure APEO of fat) one or more.
Described stabilizing agent is selected from: one or more in BHT, triphenyl phosphite, epoxychloropropane, tributyl phosphate, triethanolamine, diethanol amine, the monoethanolamine.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, defoamer, the stabilizing agent etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein comparatively preferably ZEN 90160 and mancozeb are made wetting powder, water dispersible granules, suspending agent or suspension emulsion; ZEN 90160 and Propineb are made wetting powder, water dispersible granules; ZEN 90160 and zineb are made wetting powder, water dispersible granules, suspending agent, suspension emulsion; ZEN 90160 and Carbatene are made wetting powder, water dispersible granules, suspending agent, suspension emulsion;
When making wetting powder, composition comprises following constituent content: ZEN 90160 1～60%, active component B 1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
The former medicine of ZEN 90160, the former medicine of active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: ZEN 90160 1～60%, active component B 1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
The former medicine of ZEN 90160, the former medicine of active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
When making suspending agent, composition comprises following constituent content: ZEN 90160 1～20%, active component B 1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, deionized water adds to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of ZEN 90160, the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is made suspension emulsion: ZEN 90160 1～20%, active component B 1～40%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make active component B suspending agent, then with the former medicine of ZEN 90160, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
The described bactericidal composition that contains ZEN 90160 and active component B is used to prevent and treat disease due to the germ of Ascomycetes, Basidiomycetes and Fungi Imperfecti, for example can be used for many kinds of crops: fruit tree, wheat, cucumber, grape, vegetables and flowers and paddy rice, preventing and treating plant diseases such as downy mildew, leaf spot, rust, eqpidemic disease, scab, spot defoliation, anthracnose, powdery mildew, ring spot, shot hole, leaf blight has good preventive effect.
Beneficial effect of the present invention: (1) is owing to the mechanism of action difference of single agent in the said composition, the problem that does not have cross resistance, so, the application of said composition can reach and delay drug-fast generation of pathogen and development, help to prolong the result of use of this medicament, reduce the purpose that pesticide resistance produces probability.(2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage, has improved safety, and being mixed will be lower, safer to the influence of environment.(4) present composition has enlarged fungicidal spectrum, and plant diseases such as downy mildew, leaf spot, rust, eqpidemic disease, scab, spot defoliation, anthracnose, powdery mildew, ring spot, shot hole, leaf blight are had special efficacy.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Application Example one
Example 1 60% ZEN 90160 mancozeb wettable powder
ZEN 90160 10%, mancozeb 50%, polyoxyethylene carboxylate 7%, wetting and penetrating agent F 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 60% ZEN 90160 mancozeb wettable powder.
Example 2 80% ZEN 90160 mancozeb wettable powders
ZEN 90160 20%, mancozeb 60%, polycarboxylate 6%, silkworm excrement 4%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 80% ZEN 90160 mancozeb wettable powder.
Example 3 55% ZEN 90160 mancozeb water dispersible granules
ZEN 90160 15%, mancozeb 40%, alkylphenol-polyethenoxy are phonetic 8%, soapberry powder 7%, sodium bicarbonate 1.1%, kaolin add to 100%, mixed 55% ZEN 90160 mancozeb water dispersible granule.
Example 4 80% ZEN 90160 mancozeb water dispersible granules
ZEN 90160 10%, mancozeb 70%, ester polyoxyethylene are phonetic 4%, spaonin powder 4%, bentonite add to 100%, mixed 80% ZEN 90160 mancozeb water dispersible granule.
Example 5 30% ZEN 90160 mancozeb suspending agents
ZEN 90160 5%, mancozeb 25%, lignosulfonates 5%, neopelex 2%, silicone oil 0.4%, xanthans 1.1%, triethylene glycol 1.8%, deionized water add to 100%, the mixed 30% ZEN 90160 mancozeb suspending agent that gets.
Example 6 40% ZEN 90160 mancozeb suspending agents
ZEN 90160 10%, mancozeb 30%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, C
10～20Saturated fat acids 0.2%, PAA 1.6%, propane diols 1.5%, deionized water add to 100%, the mixed 40% ZEN 90160 mancozeb suspending agent that gets.
Example 7 20% ZEN 90160 mancozeb suspension emulsions
ZEN 90160 10%, mancozeb 10%, alkylnaphthalene sulfonate 8%, tea are withered 1%, silicone compound 0.1%, gelatin 1.3%, agricultural newborn 34#7%, ethylene glycol 1.9%, water add to 100%, the aforementioned formula material is mixed, make 20% ZEN 90160 mancozeb suspension emulsion.
Example 8 45% ZEN 90160 mancozeb suspension emulsions
ZEN 90160 20%, mancozeb 25%, lignosulfonates 6%, Nekal BX 3%, agricultural newborn 500#5%, sodium phosphate trimer 1.3%, polyethylene glycol 1.7%, C
8～10Aliphatic alcohols 0.2%, water add to 100%, through the mixed 45% ZEN 90160 mancozeb suspension emulsion that gets.
Example 9 65% ZEN 90160 Wettable propineb powders
ZEN 90160 10%, Propineb 55%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, wetting and penetrating agent F 5%, attapulgite add to 100%, and mixture carries out comminution by gas stream, makes 65% ZEN 90160 Wettable propineb powder.
Example 10 75% ZEN 90160 Wettable propineb powders
ZEN 90160 15%, Propineb 60%, octylphenol polyethylene oxyethylene group ether sulfate 5%, lauryl sodium sulfate 3%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 75% ZEN 90160 Wettable propineb powder.
Example 11 60% ZEN 90160 Propineb water dispersible granules
ZEN 90160 10%, Propineb 50%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, Nekal BX 6%, aluminium chloride 2%, diatomite add to 100%, the mixed 60% ZEN 90160 Propineb water dispersible granules that gets.
Example 12 80% ZEN 90160 Propineb water dispersible granules
ZEN 90160 20%, Propineb 60%, aliphatic amine polyoxyethylene are phonetic 6%, tea is withered 3%, ammonium sulfate 1%, kaolin add to 100%, mixed 80% ZEN 90160 Propineb water dispersible granules.
Example 13 72% ZEN 90160 Zineb wettable powders
ZEN 90160 12%, zineb 60%, aryl phenol polyoxyethylene succinate sulfonate 7%, silkworm excrement 6%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 72% ZEN 90160 Zineb wettable powder.
Example 14 80% ZEN 90160 Zineb wettable powders
ZEN 90160 10%, zineb 70%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 5%, soapberry powder 4%, diatomite add to 100%, and mixture carries out comminution by gas stream, makes 80% ZEN 90160 Zineb wettable powder.
Example 15 60% ZEN 90160 water dispersion granules agent of dithane
ZEN 90160 15%, zineb 45%, polyoxyethylene carboxylate 6%, neopelex 6%, urea 1.3%, kaolin add to 100%, the mixed 60% ZEN 90160 water dispersion granules agent of dithane that gets.
Example 16 70% ZEN 90160 water dispersion granules agent of dithane
ZEN 90160 20%, zineb 50%, naphthalene sulfonic acid-formaldehyde condensation product 5%, wetting and penetrating agent F 3%, bentonite add to 100%, the mixed 70% ZEN 90160 water dispersion granules agent of dithane that gets.
Example 17 20% ZEN 90160 zineb suspending agents
ZEN 90160 5%, zineb 15%, lignosulfonates 7%, spaonin powder 1%, C
8～10Aliphatic alcohols 0.5%, sodium alginate 1.6%, glycerine 1.2%, deionized water add to 100%, the mixed 20% ZEN 90160 zineb suspending agent that gets.
Example 18 36% ZEN 90160 zineb suspending agents
ZEN 90160 6%, zineb 30%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, Nekal BX 2%, silicone oil 0.3%, methylcellulose 1.1%, diethylene glycol (DEG) 1.7%, deionized water add to 100%, the mixed 36% ZEN 90160 zineb suspending agent that gets.
Example 19 10% ZEN 90160 zineb suspension emulsions
ZEN 90160 5%, zineb 5%, alkyl benzene sulfonate calcium salt 6%, spaonin powder 4%, silicone compound 0.4%, polyvinylpyrrolidone 1.2%, propane diols 1.8%, 600# phosphate 6%, water add to 100%, the aforementioned formula material is mixed, promptly make 10% ZEN 90160 zineb suspension emulsion.
Example 20 35% ZEN 90160 zineb suspension emulsions
ZEN 90160 25%, zineb 10%, polycarboxylate 5%, lauryl sodium sulfate 3%, polyvinyl alcohol 1.3%, diethylene glycol (DEG) 2%, C
10～20Saturated fat acids 0.2%, tween series 7%, water add to 100%, through the mixed 35% ZEN 90160 zineb suspension emulsion that gets.
Example 21 55% ZEN 90160 thioneb wettable powders
ZEN 90160 5%, Carbatene 50%, aliphatic amine polyoxyethylene are phonetic 7%, soapberry powder 6%, diatomite add to 100%, and mixture carries out comminution by gas stream, makes 55% ZEN 90160 thioneb wettable powder.
Example 22 75% ZEN 90160 thioneb wettable powders
ZEN 90160 15%, Carbatene 60%, lignosulfonates 5%, wetting and penetrating agent F 4%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 75% ZEN 90160 thioneb wettable powder.
Example 23 60% ZEN 90160 Carbatene water dispersible granules
ZEN 90160 10%, Carbatene 50%, alkylphenol-polyethenoxy are phonetic 8%, Nekal BX 6%, sodium carbonate 1%, bentonite add to 100%, mixed 60% ZEN 90160 Carbatene water dispersible granules.
Example 24 78% ZEN 90160 Carbatene water dispersible granules
ZEN 90160 3%, Carbatene 75%, naphthalene sulfonic acid-formaldehyde condensation product 6%, spaonin powder 4%, ammonium sulfate 2.5%, attapulgite add to 100%, the mixed 78% ZEN 90160 Carbatene water dispersible granules that gets.
Example 25 15% ZEN 90160 Carbatene suspending agents
ZEN 90160 5%, Carbatene 10%, the phonetic formaldehyde condensation products sulphate 7% of alkylphenol-polyethenoxy, wetting and penetrating agent F 2%, C
10～20Saturated fat acids 0.1%, methylcellulose 1.5%, diethylene glycol (DEG) 1.2%, deionized water adds to 100%, the mixed 15% ZEN 90160 Carbatene suspending agent that gets.
Example 26 45% ZEN 90160 Carbatene suspending agents
ZEN 90160 15%, Carbatene 30%, polyoxyethylene carboxylate 5%, lauryl sodium sulfate 3%, silicone compound 0.3%, gum Arabic 1.4%, triethylene glycol 1.7%, deionized water adds to 100%, the mixed 45% ZEN 90160 Carbatene suspending agent that gets.
Example 27 24% ZEN 90160 Carbatene suspension emulsions
ZEN 90160 12%, Carbatene 12%, alkyl benzene sulfonate calcium salt 6%, neopelex 4%, silicone oil 0.6%, ethylene glycol 1.3%, white dextrin 1.5%, agricultural newborn 400#8%, water adds to 100%, the mixed 24% ZEN 90160 Carbatene suspension emulsion that gets.
Example 28 42% ZEN 90160 Carbatene suspension emulsions
ZEN 90160 10%, Carbatene 32%, octylphenol polyethylene oxyethylene group ether sulfate 5%, wetting and penetrating agent F 5%, polyvinylpyrrolidone 1.1%, agricultural newborn 1600#6%, silicone compound 0.2%, propane diols 1.9%, water add to 100%, the mixed 42% ZEN 90160 Carbatene suspension emulsion that gets.
Wetting powder the key technical indexes of the present invention:
Table 1
Water dispersible granules the key technical indexes of the present invention:
Table 2
Suspending agent the key technical indexes of the present invention:
Table 3
Suspension emulsion the key technical indexes of the present invention:
Table 4
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
ZEN 90160 and active component B (active component B is selected from a kind of of mancozeb, Propineb, zineb, Carbatene) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component ZEN 90160 and active component B (mancozeb, Propineb, zineb, Carbatene) shared ratio in combination;
A is a ZEN 90160;
B is a kind of in mancozeb, Propineb, zineb, the Carbatene.
Implementation of an application example two:
ZEN 90160 and mancozeb are composite to the alternaria leaf spot of apple Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining ZEN 90160, the former medicine of mancozeb and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 5 ZEN 90160, mancozeb and composite toxicity test analysis of results table thereof to alternaria leaf spot of apple
As shown in Table 5, ZEN 90160, mancozeb are to the EC of alternaria leaf spot of apple
50Be respectively 8.46mg/L and 41.37mg/L.The virulence of ZEN 90160 is higher than the virulence of mancozeb.ZEN 90160 and mancozeb proportioning were at 60: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that ZEN 90160 and mancozeb were mixed in the scope at 60: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 9, synergistic effect is more obviously outstanding, synergy ratio SR maximum when ZEN 90160 and mancozeb weight ratio are 1: 5 wherein, synergistic effect is the most obvious.
Implementation of an application example three
ZEN 90160 and Propineb are composite to the citrus anthracnose Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining ZEN 90160, the former medicine of Propineb and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 6 ZEN 90160, Propineb and composite toxicity test analysis of results table thereof to citrus anthracnose
As shown in Table 6, ZEN 90160, Propineb are to the EC of citrus anthracnose
50Be respectively 8.15mg/L and 38.64mg/L.The virulence of ZEN 90160 is higher than the virulence of Propineb.ZEN 90160 and Propineb proportioning were at 60: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that ZEN 90160 and Propineb were mixed in the scope at 60: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 9, synergistic effect is more obviously outstanding, synergy ratio SR maximum when ZEN 90160 and Propineb weight ratio are 1: 5 wherein, synergistic effect is the most obvious.
Implementation of an application example four
ZEN 90160 and zineb are composite to the wheat rust Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining ZEN 90160, the former medicine of zineb and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 7 ZEN 90160, zineb and composite toxicity test analysis of results table thereof to wheat rust
As shown in Table 7, ZEN 90160, zineb are to the EC of wheat rust
50Be respectively 8.06mg/L and 37.52mg/L.The virulence of ZEN 90160 is higher than the virulence of zineb.ZEN 90160 and zineb proportioning were at 60: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that ZEN 90160 and zineb were mixed in the scope at 60: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 9, synergistic effect is more obviously outstanding, synergy ratio SR maximum when ZEN 90160 and zineb weight ratio are 1: 5 wherein, synergistic effect is the most obvious.
Implementation of an application example five
ZEN 90160 and Carbatene are composite to the cucumber downy mildew Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining ZEN 90160, the former medicine of Carbatene and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 8 ZEN 90160, Carbatene and composite toxicity test analysis of results table thereof to cucumber downy mildew
As shown in Table 8, ZEN 90160, Carbatene are to the EC of cucumber downy mildew
50Be respectively 7.96mg/L and 38.49mg/L.The virulence of ZEN 90160 is higher than the virulence of Carbatene.ZEN 90160 and Carbatene proportioning were at 60: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that ZEN 90160 and Carbatene were mixed in the scope at 60: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 9, synergistic effect is more obviously outstanding, synergy ratio SR maximum when ZEN 90160 and Carbatene weight ratio are 1: 5 wherein, synergistic effect is the most obvious.
Application Example six ZEN 90160 and mancozeb and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Pucheng County, Shaanxi Province, and test medicine is provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% ZEN 90160 suspending agent (commercial), 80% mancozeb wettable powder (commercial).
The investigation alternaria leaf spot of apple state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 9 ZEN 90160, mancozeb and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 9, can effectively prevent and treat alternaria leaf spot of apple after ZEN 90160 and mancozeb are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven ZEN 90160 and Propineb and the composite control citrus anthracnose test of pesticide effectiveness thereof
This experimental establishment is at the Yichang City, Hubei Province Zigui County, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% ZEN 90160 suspending agent (commercial), 70% Wettable propineb powder (commercial).
The preceding investigation of medicine citrus anthracnose disease index, in the their early stage dispenser, dispenser for the second time after 7 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days, 30 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 10 ZEN 90160, Propineb and the composite control citrus anthracnose test of pesticide effectiveness thereof
As can be seen from Table 10, can effectively prevent and treat citrus anthracnose after ZEN 90160 and Propineb are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight ZEN 90160 and zineb and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Woyang County, city, Haozhou, Anhui Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% ZEN 90160 suspending agent (commercial), 80% Zineb wettable powder (commercial).
The investigation wheat rust state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 10 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 11 ZEN 90160, zineb and the composite wheat rust test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 11, can effectively prevent and treat wheat rust after ZEN 90160 and zineb are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine ZEN 90160 and Carbatene and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This experimental establishment is in Shangqiu City Ningling County, Henan Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% ZEN 90160 suspending agent (commercial), 70% Carbatene water dispersible granules (commercial).
The preceding investigation of medicine cucumber downy mildew disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days, 30 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 12 ZEN 90160, Carbatene and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 12, can effectively prevent and treat cucumber downy mildew after ZEN 90160 and Carbatene are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (9)
1. bactericidal composition that contains ZEN 90160 and thiocarbamates, it is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～60%: 1～80%, described active component A is a ZEN 90160, and active component B is selected from a kind of in mancozeb, Propineb, zineb or the Carbatene.
2. the bactericidal composition that contains ZEN 90160 according to claim 1 is characterized in that: the percentage by weight of A, two kinds of active components of B is 3～50%: 5～70%.
3. the bactericidal composition that contains ZEN 90160 according to claim 2 is characterized in that: the percentage by weight of ZEN 90160 and mancozeb is 5～30%: 10～60%.
4. the bactericidal composition that contains ZEN 90160 according to claim 2 is characterized in that: the percentage by weight of ZEN 90160 and Propineb is 5～30%: 10～60%.
5. the bactericidal composition that contains ZEN 90160 according to claim 2 is characterized in that: the percentage by weight of ZEN 90160 and zineb is 5～30%: 10～60%.
6. the bactericidal composition that contains ZEN 90160 according to claim 2 is characterized in that: the percentage by weight of ZEN 90160 and Carbatene is 5～30%: 10～60%.
7. the bactericidal composition that contains ZEN 90160 according to claim 1 is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent or suspension emulsion.
8. the bactericidal composition that contains ZEN 90160 according to claim 1 is characterized in that: bactericidal composition is used to prevent and treat the plant disease of fruit tree, wheat, vegetables and flowers and paddy rice.
9. the bactericidal composition that contains ZEN 90160 according to claim 8 is characterized in that: composition is used to prevent and treat the application of downy mildew, leaf spot, rust, eqpidemic disease, scab, spot defoliation, anthracnose, powdery mildew, ring spot, shot hole, leaf blight.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015028376A1 (en) * | 2013-08-28 | 2015-03-05 | Basf Se | Use of a mixture comprising at least one strobilurine and at least one dithiocarbamate for increasing the health of silvicultural plants |
| WO2015079334A1 (en) | 2013-11-26 | 2015-06-04 | Upl Limited | A method for controlling rust |
| CN105764339A (en) * | 2013-12-05 | 2016-07-13 | Upl 有限公司 | Agrochemical compositions having increased rainfastness |
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| WO2024032875A1 (en) * | 2022-08-09 | 2024-02-15 | Specialty Operations France | Use of naphthalene sulphonate as compatibilizer in tank mix composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030749A (en) * | 1987-02-09 | 1989-02-01 | 帝国化学工业公司 | The method for preparing Fungicidal compounds |
| CN101087522A (en) * | 2004-12-23 | 2007-12-12 | 巴斯福股份公司 | Fungicidal mixtures |
| CN101437396A (en) * | 2006-03-24 | 2009-05-20 | 巴斯夫欧洲公司 | Method for combating phytopathogenic fungi |
-
2011
- 2011-04-02 CN CN 201110082950 patent/CN102239863B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030749A (en) * | 1987-02-09 | 1989-02-01 | 帝国化学工业公司 | The method for preparing Fungicidal compounds |
| CN101087522A (en) * | 2004-12-23 | 2007-12-12 | 巴斯福股份公司 | Fungicidal mixtures |
| CN101437396A (en) * | 2006-03-24 | 2009-05-20 | 巴斯夫欧洲公司 | Method for combating phytopathogenic fungi |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015028376A1 (en) * | 2013-08-28 | 2015-03-05 | Basf Se | Use of a mixture comprising at least one strobilurine and at least one dithiocarbamate for increasing the health of silvicultural plants |
| WO2015079334A1 (en) | 2013-11-26 | 2015-06-04 | Upl Limited | A method for controlling rust |
| EP3073826A4 (en) * | 2013-11-26 | 2016-10-19 | Upl Ltd | A method for controlling rust |
| EP3073826B1 (en) | 2013-11-26 | 2019-10-30 | UPL Limited | A method for controlling soybean rust |
| EP4014738A1 (en) * | 2013-11-26 | 2022-06-22 | UPL Ltd | A method for controlling rust |
| EP4014741A1 (en) * | 2013-11-26 | 2022-06-22 | UPL Ltd | A method for controlling rust |
| CN105764339A (en) * | 2013-12-05 | 2016-07-13 | Upl 有限公司 | Agrochemical compositions having increased rainfastness |
| US20160270392A1 (en) * | 2013-12-05 | 2016-09-22 | Upl Limited | Agrochemical compositions having increased rainfastness |
| US10694741B2 (en) * | 2013-12-05 | 2020-06-30 | Upl Limited | Agrochemical compositions having increased rainfastness |
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