CN106199026B - Full-automatic chemiluminescence immunoassay analysis meter - Google Patents
Full-automatic chemiluminescence immunoassay analysis meter Download PDFInfo
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- CN106199026B CN106199026B CN201610131478.7A CN201610131478A CN106199026B CN 106199026 B CN106199026 B CN 106199026B CN 201610131478 A CN201610131478 A CN 201610131478A CN 106199026 B CN106199026 B CN 106199026B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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Abstract
The present invention relates to automation biochemical analysis apparatus technical fields, disclose a kind of Full-automatic chemiluminescence immunoassay analysis meter, including rack, analysis portion and control unit, analysis portion includes transmission transfer system, sampling system, incubation system, cleaning system and Systems for optical inspection, and transmission transfer system includes automatically into cup mechanism and grasping mechanism；Sampling system includes sample scheduling institution, reagent disc mechanism and sample charging mechanism；Incubation system includes being incubated for disc mechanism and mixing mechanism；Cleaning system includes cleaning disc mechanism；Systems for optical inspection includes surveying CD mechanism and light collecting mechanism.Full-automatic chemiluminescence immunoassay analysis meter proposed by the present invention, transmission transfer system, sampling system, incubation system, cleaning system and Systems for optical inspection automatic work are controlled by control unit, make entirely to analyze operation whole-course automation in this way, it avoids individual difference, human error existing for manual operation, operate the uncertain problems such as lack of standardization, improve the accuracy of chemiluminescence immune assay.
Description
Technical field
The present invention relates to the technical field of automation biochemical analysis apparatus more particularly to a kind of Full-automatic chemiluminescence are immune
Analyzer.
Background technique
The advantages such as chemiluminescence immune assay has high sensitivity, high specificity, the range of linearity is wide, the degree of automation is high are special
Point, it has also become the main means of clinical diagnosis.But domestic automatic chemiluminescence immunoassay is started late, clinical application
Have developed rapidly, originally the only detection projects such as sex hormone, thyroid hormone are detected with chemoluminescence method, with technology into
The development of one step, tumor markers, metabolism substance, infectious disease marker, disease marker for the treatment of cardiac and cerebral vascular diseases etc. can detect
Project is more and more, meanwhile, chemiluminescence immunoassay detection also has uncertainty, which is mainly derived from test operation
And detection architecture.
Currently, most of the detecting instrument in the industry be using manually carrying out test operation, by the way of semi-automatic detection,
Detecting instrument often only realizes detection readings function, and there are individual difference, human error, operation are lack of standardization etc. no for manual operation
Certainty, drawback is completely exposed in sample size, the numerous situations of test item.Therefore, a kind of automation journey how is proposed
Spending high and detection, fast and accurately Full-automatic chemiluminescence immunoassay analysis meter is technical problem urgently to be resolved in the industry.
Summary of the invention
It is an object of the invention to overcome above-mentioned the deficiencies in the prior art, a kind of automatic chemiluminescence immunoassay is provided
Instrument realizes chemiluminescence immune assay full-automation, avoids manually-operated individual difference, human error, operates and do not advise
The uncertain problems such as model improve the accuracy of chemiluminescence immune assay.
The embodiment of the invention provides a kind of Full-automatic chemiluminescence immunoassay analysis meter, immune point of the Full-automatic chemiluminescence
Analyzer includes: rack, the analysis portion being set in the rack, and the control unit for controlling the analysis portion operation；Institute
Stating analysis portion includes:
Transfer system is transmitted, including for storing, screen and feed the automatic into cup mechanism of reaction cup, and for transferring
The grasping mechanism of the reaction cup, described to be set in the rack into cup mechanism automatically, the grasping mechanism is movably set in
Cooperate automatically into cup mechanism side and with it in the rack and positioned at described；
Sampling system can including the sample scheduling institution for being used to store and dispatch sample tube being set in the rack
It is rotatably dispose in the rack and is located at the reagent disc for being used to store and dispatch Reagent Tube of sample scheduling institution side
Mechanism is movably arranged and is used in the rack and positioned at reagent disc mechanism side by the sample in the sample tube
Transfer load to the sample charging mechanism of the reaction cup with the reagent in the Reagent Tube, the sample scheduling institution be located at it is described automatically into
Between cup mechanism and the reagent disc mechanism, and the sample charging mechanism is positioned at described automatically into cup mechanism, the sample dispatcher
Between structure and the reagent disc mechanism；
Incubation system, including being rotatably set in the rack and positioned at reagent disc mechanism side for opposed
The sample in the reaction cup thereon carries out the incubation disc mechanism for being incubated for operation, and is set in the rack and is located at
It is used to mix the sample in the reaction cup after the incubation disc mechanism is incubated on the upside of the incubation disc mechanism
The mixing mechanism of operation；
Cleaning system, including being rotatably set in the rack and positioned at the incubation disc mechanism side for warp
It is described be incubated for disc mechanism be incubated for after the reaction cup in sample carry out three ranks cleaning separation and to cleaning separation after described in
Sample in reaction cup carries out the cleaning disc mechanism of substrate filling and mixing；
Systems for optical inspection is used for including being set to the cleaning disc mechanism and described be incubated between disc mechanism to through institute
The sample in the reaction cup after stating cleaning disc mechanism cleaning separation and substrate filling and mixing carries out the survey light of optical detection
Disc mechanism, and it is set to survey CD mechanism side light collecting mechanism engaged therewith；
The control unit is set in the rack, and with the transmission transfer system, the sampling system, the incubation
System, the cleaning system and Systems for optical inspection electrical connection.
Further, the reagent disc mechanism includes the rotary case to carry the Reagent Tube, is enclosed set on the turntable
It external week and can be sequentially connected the outer pot for being carried on the intracorporal Reagent Tube of the turntable and being refrigerated in the rotary case
First driving assembly of the bottom side to drive it to rotate, and be set between the outer pot and the rotary case for driving
The Reagent Tube is rotated mix the rotating device of operation.
Further, the sampling system further includes the bar code scanner being set in the rack, and is set to
The scanning window that just can be heated in the sample scheduling institution and the rotary case and automatically after bar code scanner scanning
Mouthful.
Further, the sample charging mechanism includes being set in the rack and one end is optionally rotated to the sample
This scheduling institution, the reagent disc mechanism and the sample arm for being incubated for one of disc mechanism, be set in the rack with
The second driving assembly for driving the sample arm to rotate and go up and down, and it is set to the sample needle of the sample arm outer end.
Further, the sample scheduling institution includes the sample sample introduction track being set in the rack, and setting
Emergency treatment sample bit in the sample sample introduction track side, one end of the sample arm takes the sample needle and can turn to the sample
This sample introduction track and the emergency treatment sample bit.
Further, described includes automatically being set in the rack to be used for reaction cup described in load store into cup mechanism
Reaction cup load store portion, be set to reaction cup load store portion side and interfaced for transmitting the reaction
The reaction cup transport unit of cup, and butt up against reaction cup transport unit outer end and rotatable automatically into cup rotating disk.
Further, the grasping mechanism includes being set in the rack and one end is optionally rotated to described clear
Dishwashing mechanism, the survey CD mechanism, the incubation disc mechanism and described automatically into the crawl arm of one of cup rotating disk, if
It is placed in the third driving assembly in the rack to drive the crawl arm to rotate and go up and down, and is set to outside the crawl arm
The handgrip for being used to grab the reaction cup at end.
Further, the incubation disc mechanism includes being incubated for disk, and be sequentially connected in the bottom side for being incubated for disk to drive
Move the 4th driving assembly of its rotation.
Further, the survey CD mechanism includes rotatably being set in the rack and being located at the cleaning disc mechanism
And the optical detection disk being incubated between disk, and be set to the optical detection and try to get to the heart of a matter side with the 5th driving for driving it to rotate
Component.
Further, the Full-automatic chemiluminescence immunoassay analysis meter further includes being set in the rack to handle with collection
The collection system of the used reaction cup, the collection system include the throwing cup position abandoned for the reaction cup.
Based on the above-mentioned technical proposal, the Full-automatic chemiluminescence immunoassay analysis meter that the embodiment of the present invention proposes, passes through control
Portion's control transmission transfer system, sampling system, incubation system, cleaning system and Systems for optical inspection automatic work, so that entirely
Analysis operation whole-course automation avoids individual difference, human error existing for manual operation, operates the uncertainties such as lack of standardization
Problem improves the accuracy of chemiluminescence immune assay.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the Full-automatic chemiluminescence immunoassay analysis meter that the embodiment of the present invention proposes；
Fig. 2 is the flow diagram of the Full-automatic chemiluminescence immunoassay analysis meter work in the embodiment of the present invention.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
It should be noted that it can be directly another when element is referred to as " being fixed on " or " being set to " another element
On one element or it may be simultaneously present centering elements.When an element is known as " being connected to " another element, it can be with
It is directly to another element or may be simultaneously present centering elements.
It is only phase each other in addition, it should also be noted that, positional terms such as left and right, upper and lower in the embodiment of the present invention
It is reference to concept or with the normal operating condition of product, and should not be regarded as restrictive.Below in conjunction with tool
Realization of the invention is described in detail in body embodiment.
As shown in Figure 1 to Figure 2, the embodiment of the present invention proposes a kind of Full-automatic chemiluminescence immunoassay analysis meter comprising
Rack 1, analysis portion 2 and control unit (being not drawn into attached drawing), wherein rack 1 is the body supports part of entire analyzer, point
Analysis portion 2 and control unit are arranged in rack 1, and control unit carries out automatic chemiluminescence immunoassay for controlling analysis portion 2.
Specifically, analysis portion 2 may include transmission transfer system 21, sampling system 22, incubation system 23, cleaning system 24 and optical detection
System 25, in which:
Transfer system 21 is transmitted, including for storing, screening and feeding the automatic into cup mechanism 211, Yi Jiyong of reaction cup
In transfer automatically into the reaction cup in cup mechanism 211 to the crawl of cleaning system 24 or incubation system 23 or Systems for optical inspection 25
Mechanism 212 is arranged in rack 1 into cup mechanism 211, grasping mechanism 212 is movably arranged in rack 1 and is located at automatically here
This cooperates into 211 side of cup mechanism and with it automatically；
Sampling system 22, including be arranged in rack 1 for storing and dispatching the sample scheduling institution 221 of sample tube,
The reagent disc machine for being used to store and dispatch Reagent Tube for being located at 221 side of sample scheduling institution being rotatably provided in rack 1
Structure 222 is movably arranged in rack 1 and is used for positioned at 222 side of reagent disc mechanism by the sample and Reagent Tube in sample tube
In reagent transfer load to the sample charging mechanism 223 in reaction cup, here, sample scheduling institution 221 be located at automatically into 211 He of cup mechanism
Between reagent disc mechanism 222, and sample charging mechanism 223 is located at automatically into cup mechanism 211, sample scheduling institution 221 and reagent disc machine
Between structure 222；
Incubation system 23, including be rotatably provided in rack 1 be located at 222 side of reagent disc mechanism for being placed in
The sample in reaction cup thereon carries out the incubation disc mechanism 231 for being incubated for operation, and is arranged in rack 1 and is located at incubation disk
The mixing machine for being used to mix to the sample in the reaction cup after being incubated for disc mechanism 231 and being incubated for operation of 231 upside of mechanism
Structure 232；
Cleaning system 24, including the cleaning disc mechanism for being located at incubation 231 side of disc mechanism being rotatably provided in rack 1
241, which is used to carry out three rank cleanings to the sample in the reaction cup after being incubated for disc mechanism 231 and being incubated for
It separates and substrate filling and mixing is carried out to the sample in the reaction cup after cleaning separation, which includes that can turn
The dynamic cleaning disk 2411 being arranged in rack 1, and be arranged in below cleaning disk 2411 and be used to drive the motor of its rotation (attached
It is not drawn into figure), herein, which has heating function, by cleaning 2411 temperature of disk control, motor driven control
The rotary motion etc. of system cleaning disk 2411, realizes the cleaning three times to reaction cup, it can be achieved that substrate injects function after cleaning
Energy；
Systems for optical inspection 25, including the survey CD mechanism that cleaning disc mechanism 241 is arranged in and is incubated between disc mechanism 231
251, and be arranged in 251 side of survey CD mechanism and light collecting mechanism engaged therewith 252, herein, surveys CD mechanism 251 and use
In to the sample progress optical detection in the reaction cup after over cleaning disc mechanism 241 cleans separation and substrate is filled and mixed；
Above-mentioned control unit is arranged in rack 1, and with transmission transfer system 21, sampling system 22, incubation system 23, cleaning
System 24 and Systems for optical inspection 25 are electrically connected.
The Full-automatic chemiluminescence immunoassay analysis meter that the embodiment of the present invention proposes controls transmission transfer system by control unit
System 21, sampling system 22,25 automatic work of incubation system 23, cleaning system 24 and Systems for optical inspection, so that entire analysis behaviour
Make whole-course automation, avoid individual difference, human error existing for manual operation, operate the uncertain problems such as lack of standardization,
Improve the accuracy of chemiluminescence immune assay.
Further, in an embodiment of the present invention, mentioned reagent disc mechanism 222 may include to carry turning for Reagent Tube
Disk body 2221 is disposed around 2221 periphery of rotary case and can be refrigerated to the Reagent Tube being carried in the rotary case 2221 outer
Pot 2222, the first driving assembly (being not drawn into attached drawing) being sequentially connected in the bottom side of rotary case 2221 to drive it to rotate, with
And the rotating device for mix for driving Reagent Tube to rotate operation between outer pot 2222 and rotary case 2221 is set
(being not drawn into attached drawing).In this way, the first driving assembly starts, the axial rotation of rotary case 2221 is driven, meanwhile, outer pot 2222 is fixed
It is motionless, in this way, the rotating device between outer pot 2222 and rotary case 2221 is under the action of the axial rotation of rotary case 2221
It is rotated, Reagent Tube rotation is so driven to carry out automatic mixing operation.
Further, in an embodiment of the present invention, above-mentioned sampling system 22 may also include the bar code being arranged in rack 1
Scanning means (is not drawn into) in attached drawing, and is arranged in above-mentioned sample scheduling institution 221 and above-mentioned rotary case 2221 and by item
The scanning window (being not drawn into attached drawing) that just can be heated automatically after code scanning means scanning.In this way, bar code scanner can be passed through
Momentarily the scanning window in sample scheduling institution 221 and rotary case 2221 is heated, to prevent sample scheduling institution 221
It is atomized with rotary case 2221.Certainly, according to the actual situation and specific requirements, in other embodiments of the invention, above-mentioned
Sampling system 22 can be also other structure types, not limit uniquely herein.
Further, in an embodiment of the present invention, above-mentioned sample charging mechanism 223 may include being rotatably provided in rack 1
Sample arm 2231, be arranged in rack 1 with drive sample arm 2231 rotate and lifting the second driving assembly 2232, Yi Jishe
The sample needle (being not drawn into attached drawing) in 2231 outer end of sample arm is set, herein, the starting of the second driving assembly 2232 drives sample arm
2231 one end axially rotates, and dispatches in this way, the other end of sample arm 2231 is rotated synchronously and optionally rotated to sample
At one of mechanism 221, reagent disc mechanism 222 and incubation disc mechanism 231.When the sample or Reagent Tube for needing to draw sample tube
Reagent when, pass through manipulation control unit, control the second driving assembly 2232 start work, the second driving assembly 2232 drive sample-adding
Arm 2231 rotates, so that sample needle moves to designated position with the rotation of sample arm 2231, later, passes through 2232 liters of the second driving assembly
Sample arm 2231 drops, so that sample-adding needle lifting is drawn to suitable position with the reagent of sample or Reagent Tube to sample tube.
Further, in an embodiment of the present invention, above-mentioned sample scheduling institution 221 may include being arranged in rack 1
Sample sample introduction track 2211, and the emergency treatment sample bit 2212 of 2211 side of sample sample introduction track, herein, above-mentioned sample-adding are set
It takes sample needle and can turn to the sample sample introduction track 2211 and emergency treatment sample bit 2212 to be sampled in the outer end of arm 2231.When
So, according to the actual situation and demand, in other embodiments of the invention, above-mentioned sample scheduling institution 221 can be also others
Structure type does not limit uniquely herein.
Further, in an embodiment of the present invention, it is above-mentioned automatically into cup mechanism 211 for realizing reaction cup it is automatic into
Cup, this may include automatically the reaction cup load store portion for load store reaction cup being arranged in rack 1 into cup mechanism 211
2111,2111 side of reaction cup load store portion is set and the interfaced reaction cup transport unit for being used to transmit reaction cup
2112, and butt up against 2112 outer end of reaction cup transport unit and rotatable automatically into cup rotating disk 2113, here, this is automatic
It further include for drive response cup transport unit 2112 and automatically into the drive part (attached drawing of cup rotating disk 2113 into cup mechanism 211
In be not drawn into), herein, this is automatically into having sample-adding position 21132 in cup rotating disk 2113, herein, the sample-adding position 21132 be located at from
It moves into the position being overlapped with sample needle rotational trajectory in cup rotating disk 2113, carries out the load of sample and reagent on the position；
Meanwhile automatically into having in cup rotating disk 2113 into cup position 21131, herein, should be located at into cup position 21131 automatically into cup rotating disk
Reaction cup in this position can be grabbed and be incubated by the position being overlapped on 2113 with the handgrip rotational trajectory of grasping mechanism 212, handgrip
It educates in disc mechanism 231.Certainly, according to the actual situation and specific requirements, in other embodiments of the invention, above-mentioned automatically into cup
Mechanism 211 can be also other structure types, not limit uniquely herein.
Further, in an embodiment of the present invention, above-mentioned incubation disc mechanism 231 may include being incubated for disk 2311, Yi Jichuan
Fourth driving assembly (in attached drawing be not drawn into) of the dynamic bottom side for being connected to the incubation disk 2311 to drive it to rotate.It is controlled by manipulation
Portion processed, the 4th driving assembly of control start work, and the 4th driving assembly, which drives, is incubated for the rotation of disk 2311, herein, the incubation disk
2311 have heating function, by the way that the progress temperature control of disk 2311 is incubated for, the 4th driving Component driver control is incubated for disk 2311
Rotary motion etc. so that reaction cup completes sample-adding in being incubated for disk 2311, mixes and be incubated for work.Certainly, according to reality
Situation and demand, in other embodiments of the present invention, being incubated for disc mechanism 231 can also be other structure types, not make herein only
One limits.
In the embodiment of the present invention, above-mentioned survey CD mechanism 251 includes being rotatably provided in rack 1 and being located at above-mentioned cleaning
Optical detection disk 2511 between the cleaning disk 2411 of disc mechanism 241 and above-mentioned incubation disk 2311, and setting are examined in the optics
The 5th driving assembly (being not drawn into attached drawing) that 2511 bottom side of disk is surveyed to drive it to rotate, here, by manipulating control unit, control
5th driving assembly starts work, and the 5th driving assembly drives optical detection disk 2511 to rotate, herein, the optical detection disk 2511
With heating function.Certainly, according to the actual situation and specific requirements, in other embodiments of the invention, above-mentioned survey CD player
Structure 251 can be also other structure types, not limit uniquely herein.
In embodiments of the present invention, above-mentioned Full-automatic chemiluminescence immunoassay analysis meter further includes being arranged in rack 1 to receive
Collection handles the collection system 26 of used reaction cup, which may include the throwing cup position 261 abandoned for reaction cup.When
So, according to the actual situation and specific requirements, in other embodiments of the invention, above-mentioned Full-automatic chemiluminescence immunoassay analysis meter
It may also include other structures, be not further qualified herein.
Further, in an embodiment of the present invention, above-mentioned grasping mechanism 212 includes the crawl arm being arranged in rack 1
2121, the third driving assembly 2122 in rack 1 to drive the crawl arm 2121 to rotate and go up and down is set, and is arranged at this
The handgrip (being not drawn into attached drawing) for being used to grab reaction cup of 2121 outer end of crawl arm, herein, when third driving assembly 2122 opens
It is dynamic, drive one end of crawl arm 2121 axially to rotate, in this way, 2121 other end of crawl arm is rotated synchronously and optionally rotated
To the cleaning disk 2411 of above-mentioned cleaning disc mechanism 241, survey CD mechanism 251, it is incubated for disc mechanism 231, automatically into cup rotating disk
At the position of one of the 2113 throwing cup position 261 for grabbing cup position b and above-mentioned collection system 26.When needing transfer reaction cup
When, it can be by manipulating control unit, control third driving assembly 2122 starts, and third driving assembly 2122 drives crawl arm 2121 to revolve
Turn, so that handgrip moves to designated position with the rotation of crawl arm 2121, later, crawl arm is gone up and down by third driving assembly 2122
2121, so that handgrip is gone up and down to suitable position to grab reaction cup.In the present embodiment, on handgrip motion profile, counterclockwise
It is successively laid out are as follows: automatically into cup rotating disk 2113, the optics inspection of the incubation disk 2311 for being incubated for disc mechanism 231, survey CD mechanism 251
The cleaning disk 2411 surveyed disk 2511, clean disc mechanism 241, certainly, according to the actual situation and specific requirements, in other of the invention
In embodiment, above-mentioned grasping mechanism 212 can be also other structure types, not limit uniquely herein.
In the present embodiment, the motion profile of above-mentioned sample needle covers 2213 (i.e. sample sample introduction track of conventional sample bit
The position being overlapped with sample needle motion profile on 2211), emergency treatment sample bit 2212, be incubated for disk sample-adding position 23111 (be incubated for disk
The position being overlapped with sample needle motion profile on 2311), two cleaning solutions inhale sample position 2312 and (are located at and are incubated for disk 2311 and turntable
Between body 2221), service sink a and rotary case 2221, multiposition may be implemented and inhale sample and multiposition stock layout, flexibility ratio is high；This
Place, service sink a are distributed on the motion profile being incubated between disk 2311 and rotary case 2221.It is being incubated for disk 2311 and service sink a
Between motion profile on, be distributed with one or two placement cleaning solution position；Sample needle is in two friendships for being incubated for disk 2311
Vent sets and automatically into the addition function of sample and reagent achievable on the crossover location of cup rotating disk 2113.
In the present embodiment, the testing process of above-mentioned Full-automatic chemiluminescence immunoassay analysis meter is as follows:
Start analyzer, entire analysis process starts, automatically into the reaction cup transport unit 2112 of cup mechanism 211 by reaction cup
Reaction cup in load store portion 2111 is fed to automatically into cup rotating disk 2113 into cup position 21131, automatically into cup rotating disk
Reaction cup is transported to sample-adding position 21132 by 2113, controls sample in sample by the motor driven systems of sample scheduling institution 221
Conventional sample bit 2213 thereon is run on sample introduction track 2211, is turned by the motor driven systems control of the first driving assembly
The rotation of disk body 2221 inhales reagent sites c to run to Reagent Tube, and sample needle is inhaled from the sample tube on conventional sample bit 2213
It samples this and is added in the reaction cup being loaded on position 21132, sample needle draws reagent from the Reagent Tube inhaled on reagent sites c
And be added in the reaction cup on sample-adding position 21132, then, rotated automatically into cup rotating disk 2113, and the rotation for passing through itself
Concussion movement, completion mix the reaction liquid in reaction cup.After the completion of mixing, it will be reacted into cup rotating disk 2113 automatically
Cup, which is transported to, grabs cup position b, and the reaction cup grabbed on the b of cup position is grabbed and be transferred to be incubated in disk 2311 and is incubated for by handgrip.It is incubated for
After the completion, handgrip will be incubated for the reaction cup completed and grab and be transferred to cleaning disk 2411, carry out three ranks cleaning adsorbing separation (clear
After washing separation, reaction cup can also be grabbed by handgrip from cleaning disk 2411 and be incubated for disk 2311, then, sample needle is from rotary case
In 2221 draw reagent and be added to be incubated for disk 2311 reaction cup in, mix, be incubated for, then, handgrip will be incubated for complete it is anti-
Answer cup to grab again and be transferred to cleaning disk 2411 and carry out three ranks cleaning adsorbing separation), then pass through the bottom on cleaning disk 2411
Property management fills substrate into the reaction cup after cleaning separation and is mixed；Then, cleaning disk 2411 rotates reaction cup to grabbing
Reaction cup crawl after adding substrate and mixing is transferred to optical detection disk 2511, is incubated for, surveys light by cup position d, handgrip,
After the completion, reaction cup is grabbed from optical detection disk 2511 and is transferred to by handgrip throws cup position 261, will then complete the anti-of test
A glass jettisoning is answered, so far, entire testing process terminates.Entire testing process is automatic operation, effectively manual operation is avoided to exist
Individual difference, human error, the operation uncertain problem such as lack of standardization, in this way, improving chemiluminescence immune assay
Accuracy.
Embodiment described above, the only specific embodiment of the invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, can readily occur in various equivalent repair
Change, replace and improve etc., these modifications, replacement and improvement should be covered by the protection scope of the present invention.Therefore, this hair
Bright protection scope should be subject to the protection scope in claims.
Claims (6)
1. Full-automatic chemiluminescence immunoassay analysis meter characterized by comprising rack, the analysis portion being set in the rack,
And the control unit for controlling the analysis portion operation；The analysis portion includes:
Transfer system is transmitted, including described for storing, screening and feeding the automatic into cup mechanism of reaction cup, and for transferring
The grasping mechanism of reaction cup, described to be set in the rack into cup mechanism automatically, the grasping mechanism is movably set in described
Cooperate automatically into cup mechanism side and with it in rack and positioned at described；
Sampling system can be rotated including the sample scheduling institution for being used to store and dispatch sample tube being set in the rack
It is set in the rack and is located at the reagent disc mechanism for being used to store and dispatch Reagent Tube of sample scheduling institution side,
Be movably arranged in the rack and be located at reagent disc mechanism side for by the sample tube sample and institute
The sample charging mechanism that the reagent in Reagent Tube transfers load to the reaction cup is stated, the sample scheduling institution is located at described automatically into cup machine
Between structure and the reagent disc mechanism, and the sample charging mechanism be located at it is described automatically into cup mechanism, the sample scheduling institution and
Between the reagent disc mechanism；
Incubation system, including be rotatably set in the rack and be located at reagent disc mechanism side for being placed in it
On the reaction cup in sample carry out the incubation disc mechanism for being incubated for operation, and be set in the rack and be located at described
It is incubated on the upside of disc mechanism and is used to carry out mixing operation to the sample in the reaction cup after the incubation disc mechanism is incubated for
Mixing mechanism；
Cleaning system, including being rotatably set in the rack and positioned at the incubation disc mechanism side for described in warp
The sample being incubated in the reaction cup after disc mechanism is incubated for carries out three ranks cleaning separation and to the reaction after cleaning separation
Sample in cup carries out the cleaning disc mechanism of substrate filling and mixing；
Systems for optical inspection is used for including being set to the cleaning disc mechanism and described be incubated between disc mechanism to through described clear
The sample in the reaction cup after the cleaning separation of dishwashing mechanism and substrate filling and mixing carries out the survey CD player of optical detection
Structure, and it is set to survey CD mechanism side light collecting mechanism engaged therewith；
The control unit is set in the rack, and is with the transmission transfer system, the sampling system, the incubation
System, the cleaning system and Systems for optical inspection electrical connection；
The survey CD mechanism includes rotatably being set in the rack and being located at the cleaning disc mechanism and the incubation disk
Between optical detection disk, and be set to the optical detection try to get to the heart of a matter side with drive its rotate the 5th driving assembly；It is described to add
Model machine structure includes being set in the rack and one end is optionally rotated to the sample scheduling institution, the reagent disc machine
Structure and the sample arm for being incubated for one of disc mechanism are set in the rack to drive the sample arm to rotate and go up and down
The second driving assembly, and be set to the sample needle of the sample arm outer end；
The incubation disc mechanism includes the incubation disk with heating function, and is sequentially connected in the bottom side for being incubated for disk to drive
Move the 4th driving assembly of its rotation；It is described automatically into cup mechanism include automatically into cup rotating disk, it is described automatically into cup rotating disk,
The cleaning disk for being incubated for disk, the optical detection disk for surveying CD mechanism, the cleaning disc mechanism for being incubated for disc mechanism is in inverse
Hour hands are sequentially arranged, and the grasping mechanism includes being set in the rack and one end is optionally rotated to the cleaning disk
Mechanism, the survey CD mechanism, the incubation disc mechanism and described automatically into the crawl arm of one of cup rotating disk, are set to
Third driving assembly in the rack to drive the crawl arm to rotate and go up and down, and it is set to the crawl arm outer end
For grabbing the handgrip of the reaction cup.
2. Full-automatic chemiluminescence immunoassay analysis meter as described in claim 1, which is characterized in that the reagent disc mechanism includes
Carrying the rotary case of the Reagent Tube, enclose set on the rotary case periphery and can be intracorporal described to the turntable is carried on
The outer pot that Reagent Tube is refrigerated, the first driving assembly being sequentially connected in the bottom side of the rotary case to drive it to rotate, with
And it is set to the rotation for mix for driving the Reagent Tube to rotate operation between the outer pot and the rotary case
Device.
3. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 2, which is characterized in that the sampling system further includes
The bar code scanner being set in the rack, and be set on the sample scheduling institution and the rotary case and by institute
State the scanning window that just can be heated automatically after bar code scanner scanning.
4. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 3, which is characterized in that the sample scheduling institution packet
The sample sample introduction track being set in the rack is included, and is set to the emergency treatment sample bit of the sample sample introduction track side,
It takes the sample needle and can turn to the sample sample introduction track and the emergency treatment sample bit in one end of the sample arm.
5. Full-automatic chemiluminescence immunoassay analysis meter as claimed in claim 3, which is characterized in that described automatically into cup mechanism packet
The reaction cup load store portion for reaction cup described in load store being set in the rack is included, the reaction cup is set to
Load store portion side is simultaneously interfaced for transmitting the reaction cup transport unit of the reaction cup, and butts up against the reaction cup
Transport unit outer end and rotatable automatically into cup rotating disk.
6. such as Full-automatic chemiluminescence immunoassay analysis meter described in any one of claim 1 to 5, which is characterized in that it is described it is complete from
Dynamic chemical illumination immunity analysis instrument further includes being set in the rack to collect the collection for handling the used reaction cup
System, the collection system include the throwing cup position abandoned for the reaction cup.
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| CN106199026B true CN106199026B (en) | 2019-05-28 |
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