CN106176955A - A kind of antiinflammatory treating mammitis of cow and preparation method thereof - Google Patents

A kind of antiinflammatory treating mammitis of cow and preparation method thereof Download PDF

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Publication number
CN106176955A
CN106176955A CN201610582180.8A CN201610582180A CN106176955A CN 106176955 A CN106176955 A CN 106176955A CN 201610582180 A CN201610582180 A CN 201610582180A CN 106176955 A CN106176955 A CN 106176955A
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parts
radix
antiinflammatory
cow
time
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马荣华
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Taicang Ainong Dairy Cow Specialized Cooperative
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Taicang Ainong Dairy Cow Specialized Cooperative
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Priority to CN201610582180.8A priority Critical patent/CN106176955A/en
Publication of CN106176955A publication Critical patent/CN106176955A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of antiinflammatory treating mammitis of cow and preparation method thereof, the raw material including following weight portion forms: Herba Taraxaci 10 20 parts, Radix Scutellariae 5 10 parts, Radix Notoginseng 25 parts, Radix Bupleuri 36 parts, Radix Gentianae 4 10 parts, Cortex Mori 12 parts, Concha Haliotidis 13 parts.The present invention provides a kind of antiinflammatory to substitute traditional antibiosis and usually treats the mastitis of milch cow, make without antibiotic, green safety in milk, and the present invention uses pure Chinese medicine formula ferment in second time, especially Herba Taraxaci, wide material sources, therapeutic effect is favourable, has no side effect, and residence time in Contents in Cows is shorter, less residue, is greatly improved the comprehensive raising of the benefit of giving milk of milch cow, beneficially economic benefit and social benefit.

Description

A kind of antiinflammatory treating mammitis of cow and preparation method thereof
Technical field
The present invention relates to animal specialty anti-inflammatory drug technical field, particularly relate to a kind of antiinflammatory treating mammitis of cow And preparation method thereof.
Background technology
Along with the improvement day by day of people's living standard, food-safety problem has become the focus of global concern.People now Pursue is not only to feed oneself, and meets human body and allays one's hunger, but eats the food that nutrition is healthy again.Human body eats antibiotic remains Food can cause the growth inhibited of probiotics in human body intestinal canal, make pathogenic bacterium, candidiasis breeding, cause human body to antibiotic produce Raw drug resistance.Therefore, in recent years in the food including milk antibiotic etc residue problem be consumers in general and One of problem that entire society pays close attention to most.
Wherein, antibiotic is the effective ways for the treatment of mammitis of cow, is commonly used for curing milch cow in milk cow production Mastitis, and used by overdose continually, not only cause the drug resistance of milch cow, thus also results in milk containing highly concentrated The drug residue of degree.In milk the residual of antibiotic cannot by cleaning, soak, the method removal such as heating, therefore, antibiosis Element residual has a strong impact on dairy food quality, causes huge economic loss to milk cow production and dairy industry.
Therefore, in order to solve the technical problem of above-mentioned existence, the invention provides a kind of new technology.
Summary of the invention
It is an object of the invention to provide a kind of antiinflammatory treating mammitis of cow and preparation method thereof, use Chinese medicine to join Side is natural fermented, it is possible to be greatly reduced antiinflammatory residual quantity in Contents in Cows and residence time thereof.
The present invention is directed to above-mentioned technological deficiency be the technical scheme is that
A kind of antiinflammatory treating mammitis of cow, the raw material including following weight portion forms: Herba Taraxaci 10-20 part, Radix Scutellariae 5- 10 parts, Radix Notoginseng 2-5 part, Radix Bupleuri 3-6 part, Radix Gentianae 4-10 part, Cortex Mori 1-2 part, Concha Haliotidis 1-3 part.
Further, the raw material including following weight portion forms: Herba Taraxaci 10 parts, Radix Scutellariae 5 parts, Radix Notoginseng 2 parts, Radix Bupleuri 3 parts, Radix Gentianae 4 parts, Cortex Mori 1 part, Concha Haliotidis 1 part.
Further, the raw material including following weight portion forms: Herba Taraxaci 20 parts, Radix Scutellariae 10 parts, Radix Notoginseng 5 parts, Radix Bupleuri 6 Part, Radix Gentianae 10 parts, Cortex Mori 2 parts, Concha Haliotidis 3 parts.
It is a further object of the present invention to provide the preparation method of a kind of antiinflammatory treating mammitis of cow, including walking as follows Rapid:
A: weigh Radix Scutellariae, Radix Notoginseng, Radix Bupleuri and Radix Gentianae respectively according to above-mentioned weight portion, carries out steaming and decocting the most respectively, filters and go out Bacterium processes, and carries out one time fermentation after being respectively prepared fermentation culture fluid;
B: above-mentioned four kinds of fermentation liquids are mixed ferment in second time culture fluid, and carry out ferment in second time and process and obtain the first process Liquid;
C: weigh Herba Taraxaci, Cortex Mori and Concha Haliotidis respectively according to above-mentioned weight portion and be carried out, pulverize, be placed in steaming and decocting Device steaming and decocting, followed by filters, cools down and obtain the second treatment fluid;
D: by the first treatment fluid and the second treatment fluid mix homogeneously, and sterilizing again, concentration and freezing, can obtain and have antiinflammatory The preparation of activity.
Further, the temperature of one time fermentation described in step a is 36-38 DEG C, and the time is 1-3 days.
Further, the temperature of ferment in second time described in step b is 36-38 DEG C, and the time is 6-10 days.
The invention has the beneficial effects as follows: the present invention provides a kind of antiinflammatory to substitute traditional antibiosis and usually treats the breast of milch cow Fang Yan so that without antibiotic in milk, green safety, and also the present invention uses pure Chinese medicine formula ferment in second time, especially Pu public English, wide material sources, therapeutic effect is favourable, has no side effect, and the residence time in Contents in Cows is shorter, less residue, significantly Improve the comprehensive raising of the benefit of giving milk of milch cow, beneficially economic benefit and social benefit.
Detailed description of the invention
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, this embodiment It is only used for explaining the present invention, is not intended that the restriction to protection scope of the present invention.
Embodiment 1
The preparation method of a kind of antiinflammatory treating mammitis of cow, comprises the steps:
A: weigh Radix Scutellariae 5 parts, Radix Notoginseng 2 parts, Radix Bupleuri 3 parts and Radix Gentianae 4 parts respectively according to above-mentioned weight portion, steam the most respectively Boiling, filter and sterilization treatment, and carry out one time fermentation after being respectively prepared fermentation culture fluid, temperature is 36 DEG C, and the time is 1 My god;
B: above-mentioned four kinds of fermentation liquids are mixed ferment in second time culture fluid, and carry out ferment in second time and process and obtain the first process Liquid, ferment in second time temperature is 36 DEG C, and the time is 6 days;
C: weigh Herba Taraxaci 10 parts, Cortex Mori 1 part and Concha Haliotidis 1 part respectively according to above-mentioned weight portion and be carried out, pulverize, It is placed in boiling vessel steaming and decocting, followed by filters, cool down and obtain the second treatment fluid;
D: by the first treatment fluid and the second treatment fluid mix homogeneously, and sterilizing again, concentration and freezing, can obtain and have antiinflammatory The preparation of activity.
Embodiment 2
The preparation method of a kind of antiinflammatory treating mammitis of cow, comprises the steps:
A: weigh Radix Scutellariae 8 parts, Radix Notoginseng 4 parts, Radix Bupleuri 5 parts and Radix Gentianae 7 parts respectively according to above-mentioned weight portion, steam the most respectively Boiling, filter and sterilization treatment, and carry out one time fermentation after being respectively prepared fermentation culture fluid, temperature is 37 DEG C, and the time is 2 My god;
B: above-mentioned four kinds of fermentation liquids are mixed ferment in second time culture fluid, and carry out ferment in second time and process and obtain the first process Liquid, ferment in second time temperature is 37 DEG C, and the time is 8 days;
C: weigh Herba Taraxaci 15 parts, Cortex Mori 1.5 parts and Concha Haliotidis 2 parts respectively according to above-mentioned weight portion and be carried out, grind to form Powder, is placed in boiling vessel steaming and decocting, followed by filters, cools down and obtain the second treatment fluid;
D: by the first treatment fluid and the second treatment fluid mix homogeneously, and sterilizing again, concentration and freezing, can obtain and have antiinflammatory The preparation of activity.
Embodiment 3
The preparation method of a kind of antiinflammatory treating mammitis of cow, comprises the steps:
A: weigh Radix Scutellariae 10 parts, Radix Notoginseng 5 parts, Radix Bupleuri 6 parts and Radix Gentianae 10 parts respectively according to above-mentioned weight portion, carry out the most respectively Steaming and decocting, filtration and sterilization treatment, and carry out one time fermentation after being respectively prepared fermentation culture fluid, temperature is 38 DEG C, and the time is 3 My god;
B: above-mentioned four kinds of fermentation liquids are mixed ferment in second time culture fluid, and carry out ferment in second time and process and obtain the first process Liquid, ferment in second time temperature is 38 DEG C, and the time is 10 days;
C: weigh Herba Taraxaci 20 parts, Cortex Mori 2 parts and Concha Haliotidis 3 parts respectively according to above-mentioned weight portion and be carried out, pulverize, It is placed in boiling vessel steaming and decocting, followed by filters, cool down and obtain the second treatment fluid;
D: by the first treatment fluid and the second treatment fluid mix homogeneously, and sterilizing again, concentration and freezing, can obtain and have antiinflammatory The preparation of activity.
The invention has the beneficial effects as follows: the present invention provides a kind of antiinflammatory to substitute traditional antibiosis and usually treats the breast of milch cow Fang Yan so that without antibiotic in milk, green safety, and also the present invention uses pure Chinese medicine formula ferment in second time, especially Pu public English, wide material sources, therapeutic effect is favourable, has no side effect, and the residence time in Contents in Cows is shorter, less residue, significantly Improve the comprehensive raising of the benefit of giving milk of milch cow, beneficially economic benefit and social benefit.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for the skill of this area For art personnel, the present invention can have various modifications and variations.All within the spirit and principles in the present invention, that is made any repaiies Change, equivalent, improvement etc., should be included within the scope of the present invention.

Claims (6)

1. the antiinflammatory treating mammitis of cow, it is characterised in that: include that the raw material of following weight portion forms: Herba Taraxaci 10-20 part, Radix Scutellariae 5-10 part, Radix Notoginseng 2-5 part, Radix Bupleuri 3-6 part, Radix Gentianae 4-10 part, Cortex Mori 1-2 part, Concha Haliotidis 1-3 part.
A kind of antiinflammatory treating mammitis of cow the most according to claim 1, it is characterised in that: include following weight portion Raw material composition: Herba Taraxaci 10 parts, Radix Scutellariae 5 parts, Radix Notoginseng 2 parts, Radix Bupleuri 3 parts, Radix Gentianae 4 parts, Cortex Mori 1 part, Concha Haliotidis 1 part.
A kind of antiinflammatory treating mammitis of cow the most according to claim 1, it is characterised in that: include following weight portion Raw material composition: Herba Taraxaci 20 parts, Radix Scutellariae 10 parts, Radix Notoginseng 5 parts, Radix Bupleuri 6 parts, Radix Gentianae 10 parts, Cortex Mori 2 parts, Concha Haliotidis 3 Part.
The preparation method of a kind of antiinflammatory treating mammitis of cow the most according to claim 1, it is characterised in that: include Following steps:
A: weigh Radix Scutellariae, Radix Notoginseng, Radix Bupleuri and Radix Gentianae respectively according to above-mentioned weight portion, carries out steaming and decocting the most respectively, filters and go out Bacterium processes, and carries out one time fermentation after being respectively prepared fermentation culture fluid;
B: above-mentioned four kinds of fermentation liquids are mixed ferment in second time culture fluid, and carry out ferment in second time and process and obtain the first process Liquid;
C: weigh Herba Taraxaci, Cortex Mori and Concha Haliotidis respectively according to above-mentioned weight portion and be carried out, pulverize, be placed in steaming and decocting Device steaming and decocting, followed by filters, cools down and obtain the second treatment fluid;
D: by the first treatment fluid and the second treatment fluid mix homogeneously, and sterilizing again, concentration and freezing, can obtain and have antiinflammatory The preparation of activity.
The preparation method of a kind of antiinflammatory treating mammitis of cow the most according to claim 4, it is characterised in that: step The temperature of one time fermentation described in a is 36-38 DEG C, and the time is 1-3 days.
The preparation method of a kind of antiinflammatory treating mammitis of cow the most according to claim 4, it is characterised in that: step The temperature of ferment in second time described in b is 36-38 DEG C, and the time is 6-10 days.
CN201610582180.8A 2016-07-22 2016-07-22 A kind of antiinflammatory treating mammitis of cow and preparation method thereof Pending CN106176955A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634361A (en) * 2004-11-18 2005-07-06 西北农林科技大学 Traditional Chinese medicine powder for treating mastitis of dairy cattle
CN101322779A (en) * 2007-06-14 2008-12-17 北京大北农动物保健科技有限责任公司 Chinese medicine for treating mammitis of milk cattle and preparation thereof
CN101804105A (en) * 2010-04-15 2010-08-18 刘巧玲 Medicine composition for treating mammitis and preparation method thereof
CN104274619A (en) * 2014-10-27 2015-01-14 徐自升 Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition
CN104825625A (en) * 2015-03-18 2015-08-12 云南明侍达生物科技有限责任公司 Novel veterinary anti-inflammation agent and preparation method of same
CN105106524A (en) * 2015-07-01 2015-12-02 太仓市爱农奶牛专业合作社 Traditional Chinese medicine for treating milk cow mastitis, and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634361A (en) * 2004-11-18 2005-07-06 西北农林科技大学 Traditional Chinese medicine powder for treating mastitis of dairy cattle
CN101322779A (en) * 2007-06-14 2008-12-17 北京大北农动物保健科技有限责任公司 Chinese medicine for treating mammitis of milk cattle and preparation thereof
CN101804105A (en) * 2010-04-15 2010-08-18 刘巧玲 Medicine composition for treating mammitis and preparation method thereof
CN104274619A (en) * 2014-10-27 2015-01-14 徐自升 Externally-applied pharmaceutical composition for preventing and treating cow mastitis and preparation method of externally-applied pharmaceutical composition
CN104825625A (en) * 2015-03-18 2015-08-12 云南明侍达生物科技有限责任公司 Novel veterinary anti-inflammation agent and preparation method of same
CN105106524A (en) * 2015-07-01 2015-12-02 太仓市爱农奶牛专业合作社 Traditional Chinese medicine for treating milk cow mastitis, and preparation method thereof

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