CN104997867A - Method for preparing traditional Chinese medicine micro-ecology oral preparation for preventing ascariasis - Google Patents
Method for preparing traditional Chinese medicine micro-ecology oral preparation for preventing ascariasis Download PDFInfo
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Abstract
A method for preparing a traditional Chinese medicine micro-ecology oral preparation for preventing ascariasis comprises the steps of preparing euphorbia helioscopia, azedarach, kaladana, kaladana, pumpkin seeds, pomegranate bark, coptis chinensis, gynostemma pentaphylla, astragalus membranaceus, codonopsis pilosula and radix glycyrrhizae; conducting superfine grinding on all the traditional Chinese medicines, adding an ethanol solution, boiling with strong fire, keeping warm with slow fire, conducting cooling and filtering, concentrating filter liquor, adding white sugar, boiling, cooling to the normal temperature, inoculating lactobacillus, tea fungus and acetobacter xylinum, and obtaining white fungus blocks after fermentation is conducted for 96-118 h; conducting dilution with the proportion of the white fungus blocks to bacterial liquid being 1 to 50-80, conducting secondary fermentation for 18-24 h, and obtaining the micro-ecology oral preparation. The traditional Chinese medicine micro-ecology oral preparation can increase the number of effective microbial communities in the intestinal tract, improve immunity and improve the disease resistance of pigs. The oral preparation has the advantages that preventing effect is good, cure rate reaches 90.0%, preparing method is simple, viable content is high, using is convenient, environment friendliness is realized, and no residue exists.
Description
Technical field
The invention belongs to microbial forage additive technical field, relate to a kind of preparation method of green natural environmental protection pig Traditional Chinese drug microecology oral agents of control ascaris suum disease specifically.
Background technology
Ascaris suum belongs to the large-scale nematicide of one that Ascaridina Ascaridae ascarid belongs to.Worm's ovum has germ cell and unfertilized egg 2 kinds.Germ cell is short ellipse, yellowish-brown, size 50 ~ 75 μm × 40 ~ 60 μm, and chorion is thick, and skin is scraggly albuminous membranae, in be true film, interior is vitellinae membrana; Unfertilized egg is oblong, Lycoperdon polymorphum Vitt, and size is 90 μm × 40 μm, and majority does not have albuminous membranae, and whole chorion is thinner, is full of the more yolk protein that differs in size and cavity in ovum.Be distributed widely in large-scale parasitic nematode all over the world, reproductive capacity is strong, and main parasitic is in the small intestinal of pig, and be one of topmost parasite of pig, infection rate can reach 50% ~ 70%.It is mainly serious to the piglet harm at 2 ~ 6 monthly ages, and show as retarded growth, weightening finish reduces, severe infections person arrest of development, and even causes death, and causes very large economic loss to pig industry.Recently research confirms, ascaris suum also can infect people, and ascaris suum and ascariasis have many similarities.Therefore, World Health Organization (WHO) and a part of country include ascaris suum disease in mankind's public health category.
The clinical manifestation of ascaris suum disease, generally infect relatively more serious with 3 ~ 6 months large pigs, Adult Pig often has stronger immunity, can tolerate the polypide harm of some, there will not be obvious clinical symptoms, but can become the important source of infection.The degree of causing a disease depending on pig age, nutriture, infection intensity and larval migration and adult parasitism is different and different.When larval migration is to lungs, piglet performance cough, body temperature raises, accelerated breathing, loss of appetite.Severe infections person can occur that dyspnea, palpitating speed, vomiting sialorrhea, depressed, the many happinesses of spirit couch, are reluctant to walk about, and through improvement in 1 ~ 2 week or weak gradually, may cause death.When intestinal has adult a large amount of parasitic, sick pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica simultaneously.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Time even more serious, due to polypide mechanical irritation damage intestinal mucosa, can occur enteritis symptom, sick pig performance is had loose bowels, and body temperature raises.After intestinal gets clogged, clonospasm colic symptom can be there is, even owing to causing enterorrhexis and dead.As polypide creeps into bile duct, sick pig starts to show dysentery, and body temperature raises, and appetite is useless absolutely, performance tormina, and dysphoria, afterwards temperature decline, do not rise sleepingly, and extremity are disorderly pedaled, and rolls uneasy, then after climb motionless and dead.As persistent period comparatively elder, visual mucosa can present jaundice.The sick pig of minority can present allergic phenomena, and erythra appears in skin, or shows spastic nervous symptoms.
The pathological change of ascaris suum disease, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, and show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Adult has a large amount of ascarid at little enteral time parasitic, and intestinal obstruction occurs, and visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer.Peritonitis as visible in enterorrhexis and hemoperitoneum.Also may find ascarid in bile duct, course of disease person of a specified duration has pyogenic cholangitis or rupture of bile duct, and intracapsular bile of gallbladder reduces, liver xanthochromia or hardening.
Chinese medicine be the Chinese nation for thousands of years produce struggle in the knowledge of natural environment, nature remodeling wisdom crystallization, be the guarantee of our national prosper.It is natural drug; obtain the corresponding various composition and ability that conform and resist various infringement during evolution; set up the regulating system (BRM) of self; the intrinsic medicine resistance ability and the material contained by Chinese medicine can be strengthened or watch for animals; and its property of medicine is gentle; toxic and side effects is little even to have no side effect, and these are all that chemicals can not be compared.Chinese veterinarian's dialectical treatmert theory think this disease be by invading in insect poison, exuberant lung-stomach heat, the blood stasis stagnation of QI cause, treatment by Chinese herbs is appropriate to the occasion based on heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, damp eliminating medicine.Much Chinese medicine all has the effect of parasite killing, antibacterial, antiinflammatory, and use treatment by Chinese herbs disease not easily to produce drug resistance, nontoxic or low toxicity, noresidue or low-residual, some Chinese medicines also have the effect regulating body function and extra-nutrition concurrently simultaneously.Therefore Chinese medicine is selected will to be the development trend that aquaculture is prevented and cured diseases to treat ascaris suum disease.
Therefore, research and develop a kind of treat ascaris suum sick and have no side effect, the medicine of drug residue free is this field scientific research technical staff new problem anxious to be resolved, and the Tiny ecosystem oral agents being prepared into and preventing and treating ascaris suum disease that Chinese medicine is fermented together with microorganism, have no report in prior art.
Summary of the invention
The object of the invention is to the deficiency for above technology, solve the current drug resistance of ascaris suum disease and the problem of antibiotic remains, there is provided a kind of preparation method with the sick Traditional Chinese drug microecology oral agents of control ascaris suum, simple, the easy to use, safe environmental protection of this preparation method, pure ecology, noresidue, viable bacteria content are high.
For achieving the above object, the technical solution used in the present invention is as follows:
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, it is characterized in that: it is prepared according to the following steps: the Chinese medicine 1, weighing following weight portion: Herba Euphorbiae Helioscopiae 100 ~ 120, Cortex Meliae 100 ~ 120, Semen Pharbitidis 100 ~ 120, Fructus Carpesii 80 ~ 100, Semen Cucurbitae 80 ~ 100, Pericarpium Granati 60 ~ 80, Rhizoma Coptidis 60 ~ 80, Herb Gynostemmae Pentaphylli 40 ~ 60, the Radix Astragali 30 ~ 40, Radix Codonopsis 30 ~ 40, Radix Glycyrrhizae 20 ~ 30; 2, each Study on Supermicro-pulverization of Traditional Chinese Drugs is added alcoholic solution intense fire to boil, slow fire is incubated, cold filtration, and concentrated filtrate, adds white sugar and boil, and inoculating lactobacillus, red tea fungus and acetobacter xylinum after room temperature are down in cooling, through 96 ~ 118h fermentation to growing white truffle; 3, by white truffle and bacterium liquid, dilute by 1:50 ~ 80, after ferment in second time 18 ~ 24h, obtain micro-ecological oral tonic.
Described a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum, it is characterized in that: the Chinese medicine weighing weight portion, micronizing, add the alcoholic solution of 70% ~ 80% of Chinese medicine gross weight 6 ~ 8 times amount, soak 30 ~ 60min, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% ~ 50% of 4 ~ 6 times amount again, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water and making every ml water containing 1g crude drug in concentrated solution.
Described a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum, it is characterized in that: in units of 100 Kg concentrated solutions, add white sugar 20 ~ 30Kg, and boil 3 ~ 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20 ~ 25Kg, setting fermentation temperature 35 ~ 38 DEG C, standing for fermentation cultivates 96 ~ 118h, to pH5.5 ~ 6.5 grow white truffle.
Described a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum, it is characterized in that: white truffle and bacterium liquid will be gone out, be blended into 5% ~ 10% cold Sugar water dilution by 1:50 ~ 80, fermentation temperature 33 ~ 37 DEG C, after ferment in second time 18 ~ 24h, obtain micro-ecological oral tonic.
Described a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum, is characterized in that: step 2 is carried out in aseptic fermenting cellar.
Traditional Chinese drug microecology oral agents of the present invention has increases profitable strain quantity in intestinal, improve immunologic function, strengthen the effects such as pig body premunition, and preparation method is simple, easy to use, noresidue.Beneficial effect of the present invention is to improve essential amino acids content, through city, agricultural product quality inspection Spot detection the results are shown in Table 1: the percentage ratio that aspartic acid, glutamic acid, leucine account for total amino acids total amount is as can be seen from Table 1 respectively 9.18%, 11.08%, 9.78%, improves 2-3 doubly than three seed amino acids above-mentioned in Marketing pork.
Table 1 assay statement
The prevention and therapy effect fine cure rate of beneficial effect of the present invention to ascaris suum disease reaches 90.0%, viable bacteria content height after measured content 8.45 × 10
8cfu/g.
Traditional Chinese drug microecology oral agents of the present invention is to the therapeutic test of infected pigs's ascariasis: experiment pig is sick 40 of two-way cross Landrace natural infection ascaris suum, body weight 25 ~ 30Kg, divide 4 groups at random by it, be divided into, positive controls, antibiotic matched group (albendazole), 1 fermentation group, 2 fermentation groups, often organize each 10 pigs, close healthy 10 pigs of alternative body weight are as negative control group, and experimental period is 15 days; 1 time fermentation group, 2 fermentation group fermentation liquids are freely drunk by it, antibiotic matched group albendazole soluble powder concentration of aqueous solution is that 0.2g/ml allows it freely drink, negative and positive controls is each freely drinks cold boiled water, be used in conjunction 15 days, Continuous Observation 15 days, it is all identical that duration of test respectively organizes feeding and management condition, observe the clinical symptoms of each group of pig, search for food, drink water, the situation such as spirit, feces, curative effect determinate standard is: spirit, diet, defecation recover normal, and symptom disappears be judged to healing completely; Spirit, diet, defecation take a favorable turn, and symptom obviously alleviates, and are judged to effectively; Symptom is even dead without improvement, and cut open inspection, it is invalid to be judged to, and the results are shown in Table 2.
Table 2 Traditional Chinese drug microecology oral liquid is to the sick therapeutic effect of natural infection ascaris suum
| Group | Quantity (head) | Cure number (head) | Significant figure (head) | Death toll (head) | Cure rate (%) |
| 1 fermentation group | 10 | 10 | 10 | 0 | 100.0 |
| 2 fermentation groups | 10 | 9 | 10 | 0 | 90.0 |
| Antibiotic matched group | 10 | 8 | 10 | 0 | 80.0 |
| Positive controls | 10 | 2 | 4 | 6 | 20.0 |
| Negative control group | 10 | 10 | 10 | 0 | 100.0 |
As can be seen from Table 1: 1 fermentation group and antibiotic matched group ratio heteropole remarkable (P<0.01), 2 fermentation groups and antibiotic matched group significant difference (P<0.05).Illustrate that this Chinese medicine oral liquid has good preventive and therapeutic effect to ascaris suum, wherein with 2 fermentations is optimal treatment amount, not only economy but also science.
Chinese prescription of the present invention has the functions such as parasite killing, antibacterial, eliminating pathogenic heat from blood to cure dysentery, damp eliminating, modern pharmacology shows: in side, Herba Euphorbiae Helioscopiae, Cortex Meliae, Semen Cucurbitae etc. have significant anti-trichomonal effect, Rhizoma Coptidis, Pericarpium Granati have effect of anti-inflammation, the tissue injury caused by bacteriological infection ascarid can be treated, and there is significant hepatic cholagogic damp eliminating, increase the pharmacological action of bile secretion, the Radix Astragali, Radix Codonopsis have enhancing human body immunity power, improve the resistance against diseases of pig body, Radix Glycyrrhizae makes medicine, make all medicines return through effect.All medicines share and can not only promote that Histomonas meleagridis and toxin thereof are discharged in body, and suppress polypide growth and breeding in vivo again, therefore ascaris suum disease are had to the effect for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
embodiment 1
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 100, Cortex Meliae 100, Semen Pharbitidis 100, Fructus Carpesii 80, Semen Cucurbitae 80, Pericarpium Granati 60, Rhizoma Coptidis 60, Herb Gynostemmae Pentaphylli 40, the Radix Astragali 30, Radix Codonopsis 30, Radix Glycyrrhizae 20; Micronizing, adds the alcoholic solution of 70% of Chinese medicine gross weight 6 times amount, and soak 30min, intense fire boils, slow fire insulation 30min, cooling, Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 4 times amount again, and intense fire boils, slow fire insulation 30min, cooling, Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water and making every ml water containing 1g crude drug in concentrated solution.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 3min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 96h, to pH6.5 grows white truffle; To go out white truffle and bacterium liquid, be blended into 5% cold Sugar water dilution by 1:50, fermentation temperature 33 DEG C, after ferment in second time 18, obtains micro-ecological oral tonic.
Clinical treatment example: in July, 2014, pig farm, Huaibei commodity Landrace 100, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 4 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica simultaneously.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 2
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 100, Cortex Meliae 100, Semen Pharbitidis 100, Fructus Carpesii 80, Semen Cucurbitae 80, Pericarpium Granati 60, Rhizoma Coptidis 60, Herb Gynostemmae Pentaphylli 40, the Radix Astragali 30, Radix Codonopsis 30, Radix Glycyrrhizae 20; Micronizing, adds the alcoholic solution of 70% of Chinese medicine gross weight 6 times amount, and soak 30min, intense fire boils, slow fire insulation 300min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 50% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 3min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 96h, to pH6.5 grows white truffle; To go out white truffle and bacterium liquid, be blended into 5% cold Sugar water dilution by 1:50, fermentation temperature 34 DEG C, after ferment in second time 18h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, pig farm, Huaibei commodity Landrace 500, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 3 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises, accelerated breathing, loss of appetite simultaneously.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 3
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 100, Cortex Meliae 100, Semen Pharbitidis 100, Fructus Carpesii 80, Semen Cucurbitae 80, Pericarpium Granati 60, Rhizoma Coptidis 60, Herb Gynostemmae Pentaphylli 40, the Radix Astragali 30, Radix Codonopsis 30, Radix Glycyrrhizae 20; Micronizing, adds the alcoholic solution of 80% of Chinese medicine gross weight 8 times amount, and soak 30min, intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 3min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 96h, to pH6.5 grows white truffle; To go out white truffle and bacterium liquid, be blended into 5% cold Sugar water dilution by 1:50, fermentation temperature 35 DEG C, after ferment in second time 18h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, pig farm, Suzhou commodity Landrace 200, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises, accelerated breathing, loss of appetite simultaneously.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Have a large amount of ascarid at little enteral, and intestinal obstruction occurs, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 4
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 100, Cortex Meliae 100, Semen Pharbitidis 100, Fructus Carpesii 80, Semen Cucurbitae 80, Pericarpium Granati 60, Rhizoma Coptidis 60, Herb Gynostemmae Pentaphylli 40, the Radix Astragali 30, Radix Codonopsis 30, Radix Glycyrrhizae 20; Micronizing, adds the alcoholic solution of 80% of Chinese medicine gross weight 8 times amount, and soak 30min, intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 50% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 3min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 108h, to pH6.5 grows white truffle; To go out white truffle and bacterium liquid, be blended into 5% cold Sugar water dilution by 1:50, fermentation temperature 36 DEG C, after ferment in second time 20h, obtains micro-ecological oral tonic.
Clinical treatment example: in August, 2014, pig farm, Suzhou commodity Landrace 50, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises, accelerated breathing, loss of appetite simultaneously.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 5
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 110, Cortex Meliae 110, Semen Pharbitidis 110, Fructus Carpesii 90, Semen Cucurbitae 90, Pericarpium Granati 70, Rhizoma Coptidis 70, Herb Gynostemmae Pentaphylli 50, the Radix Astragali 35, Radix Codonopsis 35, Radix Glycyrrhizae 25; Micronizing, adds the alcoholic solution of 70% of Chinese medicine gross weight 6 times amount, and soak 45min, intense fire boils, slow fire insulation 45min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 4 times amount again, and intense fire boils, slow fire insulation 45min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 18Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20Kg, setting fermentation temperature 35 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 7% cold Sugar water dilution by 1:60, fermentation temperature 37 DEG C, after ferment in second time 22h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, pig farm, Suzhou commodity Landrace 200, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises, accelerated breathing, loss of appetite simultaneously.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 6
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 110, Cortex Meliae 110, Semen Pharbitidis 110, Fructus Carpesii 90, Semen Cucurbitae 90, Pericarpium Granati 70, Rhizoma Coptidis 70, Herb Gynostemmae Pentaphylli 50, the Radix Astragali 35, Radix Codonopsis 35, Radix Glycyrrhizae 25, micronizing, add the alcoholic solution of 70% of Chinese medicine gross weight 6 times amount, soak 30min, intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 50% of 4 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 20Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20 ~ 25Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 100h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 8% cold Sugar water dilution by 1:65, fermentation temperature 33 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: in July, 2014, railing pig farm commodity Landrace 200, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 4 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, dysentery simultaneously, body temperature raises, and appetite is absolutely useless, performance tormina, dysphoria, afterwards temperature decline, do not rise sleepingly.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 7
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 110, Cortex Meliae 110, Semen Pharbitidis 110, Fructus Carpesii 90, Semen Cucurbitae 90, Pericarpium Granati 70, Rhizoma Coptidis 70, Herb Gynostemmae Pentaphylli 50, the Radix Astragali 35, Radix Codonopsis 35, Radix Glycyrrhizae 25; Micronizing, adds the alcoholic solution of 70% of Chinese medicine gross weight 8 times amount, and soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 20Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20 ~ 25Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 10% cold Sugar water dilution by 1:80, fermentation temperature 37 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: clinical treatment example: in July, 2014, railing pig farm commodity Landrace 150, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 4 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, dysentery simultaneously, body temperature raises, and appetite is absolutely useless, performance tormina, dysphoria, afterwards temperature decline, do not rise sleepingly.Cut open inspection pathology Main change ascarid larva and mainly encroach on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 8
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 110, Cortex Meliae 110, Semen Pharbitidis 110, Fructus Carpesii 90, Semen Cucurbitae 90, Pericarpium Granati 70, Rhizoma Coptidis 70, Herb Gynostemmae Pentaphylli 50, the Radix Astragali 35, Radix Codonopsis 35, Radix Glycyrrhizae 25; Micronizing, adds the alcoholic solution of 80% of Chinese medicine gross weight 8 times amount, and soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 50% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 20Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20 ~ 25Kg, setting fermentation temperature 35 ~ 38 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 8% cold Sugar water dilution by 1:50, fermentation temperature 36 DEG C, after ferment in second time 22h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, certain pig farm commodity Landrace 156, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises simultaneously, accelerated breathing, loss of appetite, the sick pig performance had is had loose bowels, and body temperature raises, after intestinal gets clogged, clonospasm colic symptom can be there is.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 9
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 120, Cortex Meliae 120, Semen Pharbitidis 120, Fructus Carpesii 100, Semen Cucurbitae 100, Pericarpium Granati 80, Rhizoma Coptidis 80, Herb Gynostemmae Pentaphylli 60, the Radix Astragali 40, Radix Codonopsis 40, Radix Glycyrrhizae 30; Micronizing, adds the alcoholic solution of 70% of Chinese medicine gross weight 6 times amount, and soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 4 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 20Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 10% cold Sugar water dilution by 1:80, fermentation temperature 37 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, certain pig farm commodity Landrace 78, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, performance cough, body temperature raises, accelerated breathing, loss of appetite, the sick pig performance had is had loose bowels, body temperature raises, and intestinal gets clogged, and occurs clonospasm colic symptom.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 10
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 120, Cortex Meliae 120, Semen Pharbitidis 120, Fructus Carpesii 100, Semen Cucurbitae 100, Pericarpium Granati 80, Rhizoma Coptidis 80, Herb Gynostemmae Pentaphylli 60, the Radix Astragali 40, Radix Codonopsis 40, Radix Glycyrrhizae 30; Micronizing, adds the alcoholic solution of 80% of Chinese medicine gross weight 6 times amount, and soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 50% of 4 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 25Kg, setting fermentation temperature 36 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 8% cold Sugar water dilution by 1:50, fermentation temperature 36 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, certain pig farm commodity Landrace 121, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, performance cough, body temperature raises, accelerated breathing, loss of appetite, the sick pig performance had is had loose bowels, body temperature raises, and intestinal gets clogged, and occurs clonospasm colic symptom.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 11
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 120, Cortex Meliae 120, Semen Pharbitidis 120, Fructus Carpesii 100, Semen Cucurbitae 100, Pericarpium Granati 80, Rhizoma Coptidis 80, Herb Gynostemmae Pentaphylli 60, the Radix Astragali 40, Radix Codonopsis 40, Radix Glycyrrhizae 30; Micronizing, adds the alcoholic solution of 70%% of Chinese medicine gross weight 8 times amount, and soak 60min, intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 6 times amount again, and intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 15Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 25Kg, setting fermentation temperature 37 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 10% cold Sugar water dilution by 1:70, fermentation temperature 37 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, certain pig farm commodity Landrace 52, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, show pica, performance cough, body temperature raises simultaneously, accelerated breathing, loss of appetite, the sick pig performance had is had loose bowels, and body temperature raises, after intestinal gets clogged, clonospasm colic symptom can be there is.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
embodiment 12
Prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, comprise the following steps:
Weigh the Chinese medicine of following weight portion (kg): Herba Euphorbiae Helioscopiae 120, Cortex Meliae 120, Semen Pharbitidis 120, Fructus Carpesii 100, Semen Cucurbitae 100, Pericarpium Granati 80, Rhizoma Coptidis 80, Herb Gynostemmae Pentaphylli 60, the Radix Astragali 40, Radix Codonopsis 40, Radix Glycyrrhizae 30; Micronizing, adds the alcoholic solution of 80% of Chinese medicine gross weight 8 times amount, and soak 60min, intense fire boils, slow fire insulation 30min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% of 6 times amount again, and intense fire boils, slow fire insulation 60min, cooling Floor 12 filtered through gauze, merges twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water in concentrated solution and making every ml water containing 1g crude drug.
The preparation of Tiny ecosystem oral agents: add white sugar 20Kg in units of 100 Kg concentrated solutions, and boil 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 25Kg, setting fermentation temperature 38 DEG C, standing for fermentation cultivates 118h, to pH7.0 grows white truffle; To go out white truffle and bacterium liquid, be blended into 10% cold Sugar water dilution by 1:80, fermentation temperature 37 DEG C, after ferment in second time 24h, obtains micro-ecological oral tonic.
Clinical treatment example: in May, 2014, Yuan Zhuan pig farm commodity Landrace 108, immune programme for children carries out epidemic disease immunity to swinery routinely.When raising to 5 monthly age, some pig main manifestations malnutrition, become thin, anemia, loss of appetite thick disorderly by hair or fashion time bad, performance cough, body temperature raises, accelerated breathing, loss of appetite.Affected pig growth is very slow, and weightening finish obviously reduces, and even stagnating becomes cad pig.Cut open inspection pathology Main change and have a large amount of ascarid at little enteral, and there is intestinal obstruction, visible small intestinal mucosa has catarrhal inflammation, hemorrhage or ulcer, ascarid larva mainly encroaches on affected pig liver, bronchus and lungs, show as the little petechial hemorrhage of liver and the muddy swelling of hepatocyte, steatosis and necrosis, making the densification that hepatic tissue becomes, bleeds profusely a little in surface.Because ascaris suum dividing a word with a hyphen at the end of a line in liver causes connective tissue proliferation, form milky speckle.Preliminary suspection is that ascaris suum disease infects.
Use micro-ecological oral tonic of the present invention, allow pig freely drink, coupling 15 days, observe swinery situation, all during medication, pig is after imbibable administration, and its mental status, appetite, breathing wait until that progressively recovering normal person all belongs to healing, and cure rate is 90%.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.
Claims (5)
1. prevent and treat a preparation method for the sick Traditional Chinese drug microecology oral agents of ascaris suum, it is characterized in that: it is prepared according to the following steps: the Chinese medicine one, weighing following weight portion: Herba Euphorbiae Helioscopiae 100 ~ 120, Cortex Meliae 100 ~ 120, Semen Pharbitidis 100 ~ 120, Fructus Carpesii 80 ~ 100, Semen Cucurbitae 80 ~ 100, Pericarpium Granati 60 ~ 80, Rhizoma Coptidis 60 ~ 80, Herb Gynostemmae Pentaphylli 40 ~ 60, the Radix Astragali 30 ~ 40, Radix Codonopsis 30 ~ 40, Radix Glycyrrhizae 20 ~ 30; Two, each Study on Supermicro-pulverization of Traditional Chinese Drugs is added alcoholic solution intense fire to boil, slow fire is incubated, cold filtration, concentrated filtrate, add white sugar to boil, inoculating lactobacillus, red tea fungus and acetobacter xylinum after room temperature are down in cooling, grow white truffle through 96 ~ 118h fermentation to pH5.5 ~ 6.5; Three, by white truffle and bacterium liquid, dilute by 1:50 ~ 80, after ferment in second time 18 ~ 24h, obtain micro-ecological oral tonic.
2. a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum according to claim 1, it is characterized in that: the Chinese medicine weighing weight portion, micronizing, add the alcoholic solution of 70% ~ 80% of Chinese medicine gross weight 6 ~ 8 times amount, soak 30 ~ 60min, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze; Filtering residue adds the alcoholic solution of 40% ~ 50% of 4 ~ 6 times amount again, intense fire boils, slow fire insulation 30 ~ 60min, cooling Floor 12 filtered through gauze, merge twice filtrate, concentration and recovery ethanol, detecting in concentrated solution concentrated without stopping during ethanol with ethanol detector, adding water and making every ml water containing 0.5g crude drug in concentrated solution.
3. a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum according to claim 1, it is characterized in that: in units of 100 Kg concentrated solutions, add white sugar 20 ~ 30Kg, and boil 3 ~ 5min, be cooled to room temperature, inoculating lactobacillus, red tea fungus, acetobacter xylinum (commercially available) preparation 20 ~ 25Kg, setting fermentation temperature 35 ~ 38 DEG C, standing for fermentation cultivates 96 ~ 118h, to pH5.5 ~ 6.5 grow white truffle.
4. a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum according to claim 1, it is characterized in that: white truffle and bacterium liquid will be grown, 5% ~ 10% cold Sugar water dilution is blended into by 1:50 ~ 80, fermentation temperature 33 ~ 37 DEG C, after ferment in second time 18 ~ 24h, obtain micro-ecological oral tonic.
5. a kind of preparation method of preventing and treating the sick Traditional Chinese drug microecology oral agents of ascaris suum according to claim 1, is characterized in that: step 2 is carried out in aseptic fermenting cellar.
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