CN104524322B - A kind of peony bud prostate tea bag and production method - Google Patents

A kind of peony bud prostate tea bag and production method Download PDF

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Publication number
CN104524322B
CN104524322B CN201410684281.7A CN201410684281A CN104524322B CN 104524322 B CN104524322 B CN 104524322B CN 201410684281 A CN201410684281 A CN 201410684281A CN 104524322 B CN104524322 B CN 104524322B
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prostate
tea bag
peony
parts
production method
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CN104524322A (en
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毛文岳
余洪智
阴英超
朱宗磊
吴震生
刘俊民
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HEZE YAOSHUN PEONY BIOTECH CO Ltd
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HEZE YAOSHUN PEONY BIOTECH CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00Tea; Tea substitutes; Preparations thereof
    • A23F3/34Tea substitutes, e.g. matè; Extracts or infusions thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
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  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the technical field of prostate Chinese medicine, specially a kind of compound prostate recovery tea bag and production method using peony bud as main component.The proportioning composition of its raw material is following components by weight:100 150 parts of tree peony dried flower stamen, 200 300 parts of coix seed, 200 300 parts of Poria cocos, 200 300 parts of haw flakes.The characteristics of present invention has that definite effect, abundant raw material, technique are easy, easily promoted.

Description

A kind of peony bud prostate tea bag and production method
Technical field
The invention belongs to the technical field of prostate Chinese medicine, specially a kind of compound using peony bud as main component Prostate recovery tea bag and production method.
Background technology
Prostatitis is the common disease of male reproductive system, and the right side of fifty group accounts for first place in Urology Surgery male patient, Group occupies the 2nd within more than 51 years old.Its incidence of disease is up to more than 8%.Its cause of disease and pathogenesis are not elucidated.Before non-bacterial Row adenositis is a kind of most common prostatitis syndrome, and its cause of disease is unclear.
The use of antibiotic is irrational in terms of the treatment of the disease, presently mainly controls symptom, symptomatic treatment, Acute attack stage can select NSAIDs.
Many scholars think that prostatectomy is not suitable for treating this disease, if excision, can influence human endocrine to assist Adjust.Prostatitis syndrome is a kind of bothersome chronic disease, tackles method without very good so far.Work as both at home and abroad Before the intracavitary advocated effect ablation treating system be a kind of new technology, but the popularization of this method is not universal.
The content of the invention
The tea bag and production method of prostatic disorders are prevented and treated it is an object of the invention to disclose a kind of medicine-food two-purpose.This Invention with definite effect, abundant raw material, technique is easy, easily promote the characteristics of.
The technical scheme is that:
A kind of peony bud prostate tea bag, the proportioning composition of its raw material is following components by weight:Tree peony 100-150 parts of dried flower stamen, 200-300 parts of coix seed, 200-300 parts of Poria cocos, 200-300 parts of haw flakes.
Wherein, tree peony dried flower stamen, coix seed, Poria cocos, the component ratio of hawthorn are 1:2:2:2.
Described tree peony dried flower stamen is the complete pistil for picking up from the red fresh peony flower of phoenix.
Described coix seed, Poria cocos, hawthorn are by technique Preparation process into 20-80 mesh particles.
The peony bud prostate tea bag production method of the present invention, step is as follows:
(1)Peony bud is dried or dried, and weeds out outer viscous pollen, water content is in 9-13%;
(2)Haw flakes are roasted, and it is 160-190 DEG C that the duration and degree of heating roasted, which is grasped, 2-5min, to the burnt brown the inside yellowish-brown in outside ;
(3)Then charred FRUCTUS CRATAEGI piece and coix seed, Poria cocos are broken into graininess with disintegrating machine respectively, screening out can not be by 10 mesh Bulky grain and can be by the fine powder in 100 mesh sieve holes;
(4)According to formula rate, above-mentioned four kinds of materials are well mixed.
Described step(2)In, haw flakes are roasted by the 2005 Chinese Pharmacopoeia methods of frying;The duration and degree of heating roasted is grasped, and is 180 DEG C, 3min, observational term, which is practised, claims yellowish-brown inside the burnt brown in outside.
Described step(2)In, it can directly use charred FRUCTUS CRATAEGI piece.
Described step(2)In, it can also be measured during large-scale production with colored color difference meter, the outer face color E* of reference value Ab38-42, the inside section color E*ab50-54.
Described step(2)In, it can also be measured during large-scale production with colored color difference meter, the outer face color E* of reference value Ab40, the inside section color E*ab52.
According to every 3.5 grams of loading tea bag bag specials of bag.
Application method:Tea bag is placed in cup, is brewed with more than 300 milliliters of boiled 90 DEG C drinking water, is treated temperature Drunk after suitable.Continuously it can brew 2-3 times.
The description of effective dose:2-3 bags for each person every day, 3 weeks be a course for the treatment of.After one course for the treatment of effectively, 2-3 course for the treatment of aftereffect Fruit is significantly.
Detection for peony bud shows, wherein the important functional component contained is phytosterol, inositol, squalene Deng, and conventional pharmaceutical research is proved, rape pollen rich in phytosterol because become Chinese patent drug " QIANLIEKANG JIAONANG " Main component.The pharmaceutical research of the present invention proves that peony bud extract has for non-bacterial prostatitis animal model There is good result.So peony bud is principal component in the present invention.In order to strengthen the function association of the different foods of efficacy exertion Same-action, will also be with following ingredients compound compatibility in this product production:
Coix seed is conventional Chinese medicine, is also food.China's Chinese herbology thinks that its property slightly sweet flavor is slightly cold, and favourable water disappears The effects such as swollen, invigorating spleen to remove dampness, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus, for conventional damp-clearing drug.
Poria cocos mild in medicine property and, dampness removing is without hindering healthy tendency.Take in right amount and can take good care of good merchantable brand as spring and summer wet season.Chinese medicine Difficult urination, oedema turgor, phlegm and retained fluid can be controlled and cough inverse, vomit inverse, vomiting during early pregnancy, diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful etc. by learning load Poria cocos Disease.
Hawthorn also belongs to dietotherapeutic article, and the traditional Chinese medical science thinks, hawthorn has stagnant disperse accumulationsization, convergence and dysentery, activated blood circulation and dispersed blood clots The effects such as.Cure mainly the diseases such as eating accumulation, chest diaphragm feeling of fullness, hernia blood stasis amenorrhoea.
Formula has a two aspect benefits more than in production, one be treat prostatic disorders effect it is definite, two be wind Taste is good, and consumer is easy to receive.
The Physico-chemical tests of product of the present invention show that the product is rich in phytosterol and biological flavone.
The method for detecting phytosterol is liquid chromatography.
Detection biological flavone uses NaNO2-Al(NO3)The chemical light absorption method of 3-NaOH systems complexing, rutin comparison liquid tree peonies Pistil general flavone extract optimal processing parameter be:The % of concentration of alcohol 80, solid-liquid ratio 1:20, supersonic frequency is 30 kHz, time 20 min.General flavone content in peony bud is 18.85 mg/g.
Beneficial effects of the present invention:
Animal functional experiment:
Method:Using Kunming mouse castration.Feed testosterone propionate 5mgkg within continuous 3 weeks, make prostatic hyperplasia model. Model mice is divided into 4 groups, one group of blank group is separately set respectively and gives same volume physiological saline;It is administered once daily, successive administration 21 d.Put to death mouse after the h of last dose 2, observing and nursing mice serum testosterone, estradiol level, prostate index and prostate, The influence of thymic tissue form.As a result:With prostatic hyperplasia model group ratio, product testing group can significantly reduce hyperplasia of prostate mould Type mice serum testosterone levels, significantly raise serum estradiol level;Model mice prostate index can be significantly reduced, makes prostatitis Gland hyperplasia significantly mitigates;Thymus gland can be made significantly to thicken, lymphocyte number significantly increases.Conclusion:Invention product is to testosterone propionate institute Castration mouse hyperplasia of prostate is caused to have functions that.The provable product, which has, mitigates the effect of non-bacterial prostatitis symptom.
Human experiment clinical test:The tea bag prepared using embodiment 1
32 males of this group, patient age 45-72 Sui, the average 4.5 years case Clinical presentation and features of the course of disease are shown in urine Liquid discharge is difficult, difficult urination, and rectal touch inspection can have hypertrophy of the prostate or the obvious voiced sound of bladder area percussion, before B ultrasound prompting Row gland is loose.Diagnostic criteria meets State Administration of Traditional Chinese Medicine's disease of tcm Standardization of diagnosis and curative effect.
Treatment method:The said goods preparation, early, 2-3 bags of noon sub-service every 2 weeks is 1 course for the treatment of.
Criterion of therapeutical effect:
It is effective:Symptom disappears, and ultrasonic image shows that hyperplasia of prostate is obviously reduced.
Effectively:Symptom improves, and ultrasonic image shows that hyperplasia of prostate slightly reduces.
It is invalid:Symptom is unchanged.
Treatment results:In 32 patients after 1 course of therapy, effective 17 account for 53.13%;Effective 12 account for 37.5%;Invalid 3 account for 9.37%.
The products material is the raw-food material of regulation license, and manufactured goods belong to processed food class-alternative tea type.Always It, the characteristics of present invention has that definite effect, abundant raw material, technique are easy, easily promoted.
Embodiment
Technical scheme is described in detail below by specific embodiment.
Embodiment 1
Peony bud prostate tea bag, the proportioning composition of its raw material is following components by weight:Tree peony dried flower 100 parts of stamen, 200 parts of coix seed, 200 parts of Poria cocos, 200 parts of haw flakes.
Described tree peony dried flower stamen is the complete pistil for picking up from the red fresh peony flower of phoenix.
Described coix seed, Poria cocos, hawthorn are by technique Preparation process into 20-80 mesh particles.
The peony bud prostate tea bag production method of the present invention, step is as follows:
(1)Peony bud is dried or dried, and weeds out outer viscous pollen, water content is in 9-13%;
(2)Haw flakes are roasted, and it is 180 DEG C that the duration and degree of heating roasted, which is grasped, 3min, to the burnt brown the inside yellowish-brown in outside;
(3)Then charred FRUCTUS CRATAEGI piece and coix seed, Poria cocos are broken into graininess with disintegrating machine respectively, screening out can not be by 10 mesh Bulky grain and can be by the fine powder in 100 mesh sieve holes;
(4)According to formula rate, above-mentioned four kinds of materials are well mixed.
According to every 3.5 grams of loading tea bag bag specials of bag.
Application method:Tea bag is placed in cup, is brewed with more than 300 milliliters of boiled 90 DEG C drinking water, is treated temperature Drunk after suitable.Continuously it can brew 2-3 times.
The description of effective dose:2-3 bags for each person every day, 3 weeks be a course for the treatment of.After one course for the treatment of effectively, 2-3 course for the treatment of aftereffect Fruit is significantly.
Embodiment 2
Peony bud prostate tea bag, the proportioning composition of its raw material is following components by weight:Tree peony dried flower 100 parts of stamen, 300 parts of coix seed, 300 parts of Poria cocos, 200 parts of haw flakes.
Described tree peony dried flower stamen is the complete pistil for picking up from the red fresh peony flower of phoenix.
Described coix seed, Poria cocos, hawthorn are by technique Preparation process into 20-80 mesh particles.
The peony bud prostate tea bag production method of the present invention, step is as follows:
(1)Peony bud is dried or dried, and weeds out outer viscous pollen, water content is in 9-13%;
(2)Haw flakes are roasted, and can directly use charred FRUCTUS CRATAEGI piece;The outer face color E*ab38-42 of reference value, the inside section face Color E*ab50-54.
(3)Then charred FRUCTUS CRATAEGI piece and coix seed, Poria cocos are broken into graininess with disintegrating machine respectively, screening out can not be by 10 mesh Bulky grain and can be by the fine powder in 100 mesh sieve holes;
(4)According to formula rate, above-mentioned four kinds of materials are well mixed.
According to every 3.5 grams of loading tea bag bag specials of bag.
Application method:Tea bag is placed in cup, is brewed with more than 300 milliliters of boiled 90 DEG C drinking water, is treated temperature Drunk after suitable.Continuously it can brew 2-3 times.
The description of effective dose:2-3 bags for each person every day, 3 weeks be a course for the treatment of.After one course for the treatment of effectively, 2-3 course for the treatment of aftereffect Fruit is significantly.
Embodiment 3
Peony bud prostate tea bag, the proportioning composition of its raw material is following components by weight:Tree peony dried flower 150 parts of stamen, 200 parts of coix seed, 300 parts of Poria cocos, 300 parts of haw flakes.
Described tree peony dried flower stamen is the complete pistil for picking up from the red fresh peony flower of phoenix.
Described coix seed, Poria cocos, hawthorn are by technique Preparation process into 20-80 mesh particles.
The peony bud prostate tea bag production method of the present invention, step is as follows:
(1)Peony bud is dried or dried, and weeds out outer viscous pollen, water content is in 9-13%;
(2)Haw flakes are roasted, and it is 190 DEG C that the duration and degree of heating roasted, which is grasped, 2min, to the burnt brown the inside yellowish-brown in outside, Measured with colored color difference meter, the outer face color E*ab40, the inside section color E*ab52 of reference value;
(3)Then charred FRUCTUS CRATAEGI piece and coix seed, Poria cocos are broken into graininess with disintegrating machine respectively, screening out can not be by 10 mesh Bulky grain and can be by the fine powder in 100 mesh sieve holes;
(4)According to formula rate, above-mentioned four kinds of materials are well mixed.
According to every 3.5 grams of loading tea bag bag specials of bag.
Application method:Tea bag is placed in cup, is brewed with more than 300 milliliters of boiled 90 DEG C drinking water, is treated temperature Drunk after suitable.Continuously it can brew 2-3 times.
The description of effective dose:2-3 bags for each person every day, 3 weeks be a course for the treatment of.After one course for the treatment of effectively, 2-3 course for the treatment of aftereffect Fruit is significantly.

Claims (8)

1. a kind of peony bud prostate tea bag, the proportioning composition of its raw material is following components by weight:Tree peony does 100-150 parts of pistil, 200-300 parts of coix seed, 200-300 parts of Poria cocos, 200-300 parts of haw flakes;Tree peony dried flower stamen, Job's tears Benevolence, Poria cocos, the component ratio of hawthorn are 1:2:2:2.
2. peony bud prostate tea bag according to claim 1, it is characterised in that described tree peony dried flower stamen is to adopt From the complete pistil of the red fresh peony flower of phoenix.
3. peony bud prostate tea bag according to claim 1, it is characterised in that described coix seed, Poria cocos, mountain Short, bristly hair or beard presses technique Preparation process into 20-80 mesh particles.
4. peony bud prostate tea bag production method as claimed in claim 1, step is as follows:
(1)Peony bud is dried or dried, and weeds out outer viscous pollen, water content is in 9-13%;
(2)Haw flakes are roasted, and it is 160-190 DEG C that the duration and degree of heating roasted, which is grasped, 2-5min, are to the burnt brown the inside yellowish-brown in outside Can;
(3)Then charred FRUCTUS CRATAEGI piece and coix seed, Poria cocos are broken into graininess with disintegrating machine respectively, screening out can not be big by 10 purposes Particle and can be by the fine powder in 100 mesh sieve holes;
(4)According to formula rate, above-mentioned four kinds of materials are well mixed.
5. peony bud prostate tea bag production method according to claim 4, it is characterised in that described step (2)In, haw flakes are roasted by the 2005 Chinese Pharmacopoeia methods of frying;The duration and degree of heating roasted is grasped, and is 180 DEG C, 3min, and observational term, which is practised, to be claimed Yellowish-brown inside Jiao's brown of outside.
6. peony bud prostate tea bag production method according to claim 4, it is characterised in that described step (2)In, it can directly use charred FRUCTUS CRATAEGI piece.
7. peony bud prostate tea bag production method according to claim 4, it is characterised in that described step (2)In, measured during large-scale production with colored color difference meter, the outer face color E*ab38-42, the inside section color E* of reference value ab50-54。
8. peony bud prostate tea bag production method according to claim 7, it is characterised in that described step (2)In, measured during large-scale production with colored color difference meter, the outer face color E*ab40, the inside section color E*ab52 of reference value.
CN201410684281.7A 2014-11-25 2014-11-25 A kind of peony bud prostate tea bag and production method Active CN104524322B (en)

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Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103190504A (en) * 2013-04-22 2013-07-10 菏泽尧舜牡丹生物科技有限公司 Method for processing peony pistil tea

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103190504A (en) * 2013-04-22 2013-07-10 菏泽尧舜牡丹生物科技有限公司 Method for processing peony pistil tea

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* Cited by examiner, † Cited by third party
Title
山楂水"克制"慢性前列腺炎;朱晓平;《恋爱婚姻家庭(养生)》;20111130;第38-39页 *

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