CN106074846A - A kind of wiping agent treating neonatal dacryocystitis and preparation method thereof - Google Patents
A kind of wiping agent treating neonatal dacryocystitis and preparation method thereof Download PDFInfo
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- CN106074846A CN106074846A CN201610434347.6A CN201610434347A CN106074846A CN 106074846 A CN106074846 A CN 106074846A CN 201610434347 A CN201610434347 A CN 201610434347A CN 106074846 A CN106074846 A CN 106074846A
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Abstract
The invention discloses a kind of wiping agent treating neonatal dacryocystitis, take off and state the primary raw material of weight proportion and be prepared from: Rhizoma Arisaematis 1.0 2.0 parts, Fructus Ligustri Lucidi 35 parts, Fructus Leonuri 15 parts, Herba portulacae 46 parts, Herba Taraxaci 10 20 parts, Cortex Jujubae 5 10 parts, Radix Et Rhizoma Rhei 20 30 parts, Flos Lonicerae 36 parts, Herba Galii Teneri 10 15 parts, Herba seu Fructus Physalis Minimae 2.5 3.5 parts, Radix Sophorae Flavescentis 8 12 parts.The present invention has easy to carry, and action effect is obvious, can quickly play antiinflammatory, sterilization, antipruritic, the effect of improving eyesight, and it use the most relatively conventional Chinese crude drug as raw material, with low cost.
Description
Technical field
The invention discloses a kind of wiping agent, a kind of wiping agent treating neonatal dacryocystitis and preparation side thereof
Method.The invention belongs to traditional Chinese medicine field.
Background technology
Neonatal dacryocystitis also known as congenital dacryocystitis, be due to nasolacrimal duct lower ending opening at the residual film of embryo growing
Not recoiling in journey, or because opening part is blocked by epithelium chip, cause nasolacrimal duct obstructed, tear and antibacterial retention are at lachrymal sac
In, cause caused by secondary infection.Clinical manifestation is the tear that overflows, and conjunctival sac has a little mucus purulent secretion, and lachrymal sac local is the most grand
Rising, inner skin is sometimes congested or occurs that eczema, compressing lachrymal sac district have mucus or mucus purulent secretion to overflow.Primary disease need to be with
Ophthalmia neonatorum differentiates mutually.
The cause of disease: owing to the residual film of the embryo at nasolacrimal duct lower ending opening does not recoils in growth course, or because opening part is upper
Skin chip is blocked, and causes nasolacrimal duct obstructed, and tear and antibacterial retention, in lachrymal sac, cause caused by secondary infection.
Clinical manifestation: overflow tear, conjunctival sac has a little mucus purulent secretion, lachrymal sac local slightly to swell, and inner skin has
Time congested or occur that eczema, compressing lachrymal sac district have mucus or mucus purulent secretion to overflow.
In the method for existing treatment neonatal dacryocystitis, application publication number CN 104189335 A(application number
201410443306.4) a kind of children's's dacryocystisis nursing irrigation of lacrimal passage liquid is disclosed, it is characterised in that by following weight proportion
Medical material be prepared from: Herba equiseti ramosissimi 15-25 part, Folium Mali Asiaticae 15-45 part, Herba Hieracii Umbellati 50-75 part, Herba Lysimachiae 70-120 part,
Cacumen Securinegae Suffruticosae 40-70 part, Radix Gentianae 35-60 part, Flos Eriocauli 75-100 part, Sanguis Draxonis 5-15 part, Radix Et Rhizoma Rhei 15-45 part, Galla Chinensis
20-40 part, Flos Lonicerae 16-26 part, Flos Chrysanthemi Indici 20-38 part, Flos Buddlejae 18-34 part 16-40 part, Flos Carthami 5-15 part, fan
The most fragrant 8-12 part, lavandula angustifolia 6-14 part.Application publication number CN 105233024 A(application number 201510674796.3) open
A kind of Chinese medicine ointment treating dacryocystisis, it is characterised in that: include the raw material of following parts by weight: Medulla Tetrapanacis 4-8, Radix Et Rhizoma Rhei 7-9,
Herba Ipomoeae Pes-Capraes 5-6, Herba Menthae 4-6, Radix Saposhnikoviae 6-8, Fructus Arctii 3-5, Fructus Bruceae 3-4, Folium Eriobotryae 6-12, Radix Sophorae Flavescentis 6-10, Cortex Eucommiae 6-8, five
Cortex Acanthopanacis Radicis 8-10, Caulis Spatholobi 10-15, Radix Astragali 8-10, bitter 10-15, Flos Buddlejae 8-12, Rhizoma Chuanxiong 6-10, Rhizoma Arundinis Donacis 3-6, Herba Polygalae Japonicae
10-12, Fructus Broussonetiae 6-10, Faeces Vespertilionis 5-10, Herba speranskiae tuberculatae 10-15, Radix Dipsaci 8-10, Radix Et Rhizoma Nardostachyos 6-8, Radix Polygalae 6-8, Yin evil 3-5, Herba Ephedrae
6-10.Existing patent is primarily directed to dacryocystisis of being grown up, and neonatal dacryocystitis also be there is no to the medicine of specialty, if
Use the medicine for the treatment of adult's dacryocystisis to neonate, because of dosage bad grasp, neonate can be damaged, can be to trouble
The health of person causes extra burden.
Summary of the invention
For the present situation that existing treatment neonatal dacryocystitis is not enough, an object of the present invention is to provide one to treat newly
The wiping agent of raw youngster's dacryocystisis, has easy to carry, and action effect is obvious, can quickly play antiinflammatory, sterilization, antipruritic, improving eyesight
Effect, and it use the most relatively conventional Chinese crude drug as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned wiping agent.
The above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of wiping agent treating neonatal dacryocystitis, takes off and states the primary raw material of weight proportion and be prepared from: Rhizoma Arisaematis 1.0-
2.0 parts, Fructus Ligustri Lucidi 3-5 part, Fructus Leonuri 1-5 part, Herba portulacae 4-6 part, Herba Taraxaci 10-20 part, Cortex Jujubae 5-10 part, Radix Et Rhizoma Rhei 20-
30 parts, Flos Lonicerae 3-6 part, Herba Galii Teneri 10-15 part, Herba seu Fructus Physalis Minimae 2.5-3.5 part, Radix Sophorae Flavescentis 8-12 part.
A kind of wiping agent treating neonatal dacryocystitis, optimum ratio, take off state weight proportion primary raw material preparation and
Become: Rhizoma Arisaematis 1.3-1.8 part, Fructus Ligustri Lucidi 3.5-4.5 part, Fructus Leonuri 2-4 part, Herba portulacae 4.5-5.5 part, Herba Taraxaci 13-18 part,
Cortex Jujubae 6-8 part, Radix Et Rhizoma Rhei 23-28 part, Flos Lonicerae 4-5 part, Herba Galii Teneri 11-14 part, Herba seu Fructus Physalis Minimae 2.8-3.3 part, Radix Sophorae Flavescentis 9-11 part.
A kind of wiping agent treating neonatal dacryocystitis, more preferably preferably proportioning, takes off the primary raw material stating weight proportion
It is prepared from: Rhizoma Arisaematis 1.5 parts, Fructus Ligustri Lucidi 4 parts, Fructus Leonuri 3 parts, Herba portulacae 5 parts, Herba Taraxaci 15 parts, Cortex Jujubae 7 parts, Radix Et Rhizoma Rhei
25 parts, Flos Lonicerae 4.5 parts, Herba Galii Teneri 12 parts, Herba seu Fructus Physalis Minimae 3.0 parts, Radix Sophorae Flavescentis 10 parts.
The preparation method of above-mentioned wiping agent, preparation process is as follows:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 3-7 hour, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls
Stand-by；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 2-4 hour, taking-up slow fire stir-fries 4-8 minute repeatedly, takes out to dry and grinds
Wearing into smalls, to cross 80-120 mesh sieve stand-by；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 20-40 minute every time, and twice filtrate merges, concentrated juice paste,
Add 1-3 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and do
Dry i.e. obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 8-12 minute, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add the light salt brine of mixture weight 2-4 times, put in water-bath heating, be stirred continuously
Make mixture dissolve, after cooling, i.e. obtain wiping agent.
Above-mentioned preparation method, preferred scheme is: 1. Cortex Jujubae is cleaned by step, even with yellow wine spray, stands 4-6 hour
(preferably Cortex Jujubae is cleaned, even with yellow wine spray, stand 5 hours).
Above-mentioned preparation method, preferred scheme is: the consumption of step 2. white vinegar is Herba portulacae and the 3-5 of Flos Lonicerae weight
Times (preferably, the consumption of white vinegar is Herba portulacae and 3.5-4.5 times of Flos Lonicerae weight, and the most preferably, the consumption of white vinegar is horse
Tooth bamboo water pipe and 4 times of Flos Lonicerae weight).
Above-mentioned preparation method, preferred scheme is: 2. step soaks 2.5-3.5 hour with white vinegar, and taking-up slow fire is anti-
Stir-fry 5-7 minute (preferably soaking 3 hours with white vinegar, taking-up slow fire stir-fries 6 minutes repeatedly) again.
Above-mentioned preparation method, preferred scheme is: 3. Herba Taraxaci is made coarse powder by step, and water carries twice, boils every time
25-35 minute (the most 3. Herba Taraxaci being made coarse powder, water carries twice, boils 30 minutes every time).
Above-mentioned preparation method, preferred scheme is: the least fire of step dries 9-11 minute slowly, and (the least fire dries 10 points slowly
Clock).
Above-mentioned preparation method, preferred scheme is: the light salt brine that 5. step adds mixture weight 2.5-3.5 times is (excellent
Choosing adds the light salt brine of mixture weight 3 times).
This wiping agent is notable to the effect of neonatal dacryocystitis, and not only antiinflammatory, sterilization, antipruritic, improving eyesight are wiped by this wiping agent
Wipe neonate lip, moreover it is possible to prevention jaundice, and the many optionally common medical materials in side of the present invention, cheap, alleviate the warp of patient
Ji burden.
A kind of wiping agent treating neonatal dacryocystitis, the pharmacological effect of each crude drug is respectively as follows:
Rhizoma Arisaematis: for the plant of Bryaceae rhodobryum spp plant warm ground great Ye moss.Composition: plant contain volatile oil, flavonoid,
Steroidal, aminoacid, saccharide, glycoside, terpenoid etc..The property of medicine: pungent, bitter, flat.Function cures mainly: tranquilizing by nourishing the heart, liver heat removing and eyesight improving.Cure mainly the heart
Throb with fear palpitation with a distress feeling, neurasthenia, conjunctival congestion and swelling pain, coronary heart disease etc..
Fructus Ligustri Lucidi: for the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi.Composition: fruit contains triterpenes: oleanolic acid, acetyl is neat
Pier fruit acid, ursolic acid, acetyl ursolic acid；Phenolic glycoside class: p-hydroxyphenylethanol, Hydroxytyrosol, nuzhenide, Fructus Canarii albi is bitter
Glycosides, Fructus Ligustri Lucidi fruit glycosides, Fructus Ligustri Lucidi acid, Fructus Ligustri Lucidi thuja acid etc..The property of medicine: sweet, bitter, cold.Return liver, warp.Function cures mainly: liver and kidney tonifying, clearind deficient heat
You, improving eyesight.Cure mainly Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.
Fructus Leonuri: for Labiatae mother wort plant Herba Leonuri and the fruit of Herba Leonuri Sibirici.Composition: leonuri,fructus contains
Alkaloid: leonurinine alkali, stachydrine, fatty oil, oil is mainly composed of oleic acid etc..Herb class Han phenolic glycoside: A, B；Flavonoid glycoside:
Rutin, isoquercitrin, silver linden glycoside isorhamnetin-3-O-rutinoside.Iridoid glycosides.Herba Leonuri Sibirici fruit kind oil contains third
Dienes fatty acid: 7,8-eicosadienoic acids.The property of medicine: sweet, pungent, is slightly cold, mild toxicity.Return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation,
Liver heat removing and eyesight improving.Cure mainly menoxenia, dysmenorrhea, amenorrhea, puerperal the stagnant stomachache of the stasis of blood；Liver-heat is had a headache, dizzy, conjunctival congestion and swelling pain, and mesh is raw
Cataracta.
Herba portulacae: for young young stem and leaf, the Portulacaceae of amaranthaceous plant Herba Portulacae, nature and flavor: cold in nature, sweet in the mouth acid.Gui Jing: enter the heart
Warp, Liver Channel, spleen channel, large intestine channel.Function: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: pyretic toxicity dysentery, pyretic stranguria, urine retention, leucorrhea with red and white discharge,
Metrorrhagia, hemorrhoidal bleeding, skin infection carbuncle furuncle, erysipelas, scrofula, exudative dermatitis, the baldst, dysentery (defecate half-dried half dilute), toxic-heat and blood stasis, carbuncle furuncle,
Eczema, snake bite and insect sting, have blood in stool, metrostaxis, modern times are mostly used for treating enteritis, acute arthritis, cystitis, urethritis, anus
Hilitis, bleeding hemorrhoids etc..
Herba Taraxaci: function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furunculosis skin ulcer
Swollen, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Cortex Jujubae: meridian distribution of property and flavor: warm in nature is nontoxic.Function cures mainly: wash mesh, and dusk person becomes bright.Convergence, hemostasis, dry.Jujube tree
Skin is used for astringing to arrest diarrhea, eliminates the phlegm, antitussive, antiinflammatory, hemostasis.Controlling dysentery, enteritis, chronic tracheitis, blurred vision is not clear, burn and scald, outward
Hinder hemorrhage.
Radix Et Rhizoma Rhei: stem is red, gas delicate fragrance, bitter in the mouth and micro-puckery, that chews sticks to one's teeth, and has sand feeling.Autumn end the stem and leaf withered or secondary spring is sent out
Excavate before bud.Remove radicula, scrape off crust, valve cutting or section, rope wear bunchiness be dried or convection drying Chinese herb rhubarb have attack long-pending
The effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.
Flos Lonicerae: Flos Lonicerae is cold in nature, sweet in the mouth, enter lung, the heart, stomach warp, there is heat-clearing and toxic substances removing, antiinflammatory, effect of qi-restoratives treatment wind,
Cure mainly disease under distension, epidemic febrile disease heating, the disease such as pyretic toxicity carbuncle and ulcer and tumor.It makees thirsty, hyperhidrosis unhappiness, intestinal for dizzy dizziness, xerostomia
Inflammation, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas,
The disease such as parotitis, suppurative tonsillitis all has certain curative effect.
Herba Galii Teneri: have another name called saw grass, draw rattan, fly upward rattan, taste Rubiaceae clivers Herba Galii Teneri or thick Ye Lala
The herb of rattan.The property of medicine: herb is very thin, broken, surface is grayish green or green and brown color, feeble QI, acrid in the mouth, bitter in the mouth, cold nature.Composition: pig
Calamity calamity aerial parts is containing alkaloid, fruit amine Han Fructus Hordei Germinatus, jaligonic acid etc.；Thick Ye Lala rattan aerial parts contains asperuloside,
Vitamin C.Finding according to modern pharmacological research, this medical instrument has antibacterial, anticancer, the merit of heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, reducing swelling and alleviating pain
Effect, for swollen ulcer drug, appendicitis, cold, fever, hematuria etc..
Herba seu Fructus Physalis Minimae: have another name called husky lantern, sky bubble fruit, mother Wang pearl, for herb or the fruit of the little Calyx seu fructus physalis of Solanaceae monkey flower.Medicine
Property: bitter in the mouth, cool in nature.Composition: herb examines little physalein etc. containing physagulin, epoxyphysagulin, Wei, contains in seed oil
Palmic acid, stearic acid, oleic acid etc..Finding according to modern pharmacological research, this medical instrument has antiinflammatory, anticancer, clearing away heat-damp and promoting diuresis, goes only to cough
Expectorant, effect of hard masses softening and resolving, for jaundice due to damp-heat, dysuria, chronic cough and asthma, eczema.
Radix Sophorae Flavescentis: for the dry root of leguminous plant Radix Sophorae Flavescentis, excavate in spring, season in autumn two, removing root head and little supporting root, cleaning, drying,
Or take advantage of fresh slices, it is dried.It is bitter, cold.There are heat clearing and damp drying, parasite killing, the merit of diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, red in vain
Leukorrhagia, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Wiping agent of the present invention principle based on traditional Chinese medical herbal treatment neonatal dacryocystitis.The Chinese medicinal material selected all has and disappears
Inflammation, sterilization, antipruritic, improving eyesight, effect of heat-clearing and toxic substances removing, and cheap, life-time service does not also result in the financial burden of patient,
It is to treat the medicine that neonatal dacryocystitis is ideal.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited by this.
Embodiment 1: a kind of wiping agent treating neonatal dacryocystitis, each raw material is as follows: Rhizoma Arisaematis 1.0 parts, Fructus Ligustri Lucidi 3
Part, Fructus Leonuri 1 part, Herba portulacae 4 parts, Herba Taraxaci 10 parts, Cortex Jujubae 5 parts, Radix Et Rhizoma Rhei 20 parts, Flos Lonicerae 3 parts, Herba Galii Teneri 10 parts, sky
Lake 2.5 parts, Radix Sophorae Flavescentis 8 parts.
The preparation method of above-mentioned wiping agent, step is:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 3 hours, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls and treats
With；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 2 hours, taking-up slow fire stir-fries 4 minutes repeatedly, and taking-up is dried and ground to form
It is stand-by that smalls crosses 80 mesh sieves；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 20 minutes every time, and twice filtrate merges, concentrated juice paste, add
Enter 1 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and be dried i.e.
Obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 8 minutes, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add mixture weight 2 times light salt brine, put in water-bath heat, be stirred continuously and make
Mixture dissolves, and i.e. obtains wiping agent after cooling.
Model case one poplar XX, female, it is born 2 days, Chiping County, Liaocheng of Shandong Province, to fall ill in June, 2012, eye is shed tears,
Can overflow with purulent secretion at puncta, owing to child is the least, so doctor advised uses the wiping agent of the present invention.
With the special cotton swab of baby, pick a small amount of wiping agent, when child sleep soundly, the surrounding of wiping eyes gently, one
Day twice, after using 1 day, symptom starts to alleviate, and fully recovers with when 2 days, eats again wiping agent of the present invention and consolidate 2 times after recovery from illness, drug withdrawal
So far without recurrence.
Embodiment 2: a kind of wiping agent treating neonatal dacryocystitis, each raw material is as follows: Rhizoma Arisaematis 2.0 parts, Fructus Ligustri Lucidi 5
Part, Fructus Leonuri 5 parts, Herba portulacae 6 parts, Herba Taraxaci 20 parts, Cortex Jujubae 10 parts, Radix Et Rhizoma Rhei 30 parts, Flos Lonicerae 6 parts, Herba Galii Teneri 15 parts, sky
Lake 3.5 parts, Radix Sophorae Flavescentis 12 parts.
The preparation method of above-mentioned wiping agent, step is:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 7 hours, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls and treats
With；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 4 hours, taking-up slow fire stir-fries 8 minutes repeatedly, and taking-up is dried and ground to form
It is stand-by that smalls crosses 120 mesh sieves；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 40 minutes every time, and twice filtrate merges, and concentrated juice paste adds
3 times amount ethanol, are sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and be drying to obtain
Rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 12 minutes, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add mixture weight 4 times light salt brine, put in water-bath heat, be stirred continuously and make
Mixture dissolves, and i.e. obtains wiping agent after cooling.
Embodiment 3 one kinds treats the wiping agent of neonatal dacryocystitis, and each raw material is as follows: Rhizoma Arisaematis 1.3 parts, Fructus Ligustri Lucidi 3.5
Part, Fructus Leonuri 2 parts, Herba portulacae 4.5 parts, Herba Taraxaci 13 parts, Cortex Jujubae 6 parts, Radix Et Rhizoma Rhei 23 parts, Flos Lonicerae 4 parts, Herba Galii Teneri 11 parts,
Herba seu Fructus Physalis Minimae 2.8 parts, Radix Sophorae Flavescentis 9 parts.
The preparation method of above-mentioned wiping agent, step is:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 4 hours, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls and treats
With；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 2.5 hours, taking-up slow fire stir-fries 5 minutes repeatedly, takes out and shines dry grinding
Smalls is become to cross 90 mesh sieves stand-by；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 25 minutes every time, and twice filtrate merges, concentrated juice paste, add
Enter 1.5 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and be dried
Obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 9 minutes, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add mixture weight 2.5 times light salt brine, put in water-bath heat, be stirred continuously
Make mixture dissolve, after cooling, i.e. obtain wiping agent.
Embodiment 4 one kinds treats the wiping agent of neonatal dacryocystitis, and each raw material is as follows: Rhizoma Arisaematis 1.8 parts, Fructus Ligustri Lucidi 4.5
Part, Fructus Leonuri 4 parts, Herba portulacae 5.5 parts, Herba Taraxaci 18 parts, Cortex Jujubae 8 parts, Radix Et Rhizoma Rhei 28 parts, Flos Lonicerae 5 parts, Herba Galii Teneri 14 parts,
Herba seu Fructus Physalis Minimae 3.3 parts, Radix Sophorae Flavescentis 11 parts.
The preparation method of above-mentioned wiping agent, step is:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 6 hours, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls and treats
With；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 3.5 hours, taking-up slow fire stir-fries 7 minutes repeatedly, takes out and shines dry grinding
Smalls is become to cross 110 mesh sieves stand-by；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 35 minutes every time, and twice filtrate merges, concentrated juice paste, add
Enter 2.5 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and be dried
Obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 11 minutes, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add mixture weight 3.5 times light salt brine, put in water-bath heat, be stirred continuously
Make mixture dissolve, after cooling, i.e. obtain wiping agent.
Two XX of model case, man, Zhengzhou, henan people, in December, 2012 morbidity, symptom: glasses permanent current tear, dividing of eyes
Secretion is more, uses the wiping agent of the present invention.
With the special cotton swab of baby, pick a small amount of wiping agent, when child sleep soundly, the surrounding of wiping eyes gently, one
Day twice, after using 1 day, symptom starts to alleviate, and fully recovers with when 2 days, eats again wiping agent of the present invention and consolidate 2 times after recovery from illness, drug withdrawal
So far without recurrence.
Embodiment 5 one kinds treats the wiping agent of neonatal dacryocystitis, and each raw material is as follows: Rhizoma Arisaematis 1.5 parts, Fructus Ligustri Lucidi 4 parts,
Fructus Leonuri 3 parts, Herba portulacae 5 parts, Herba Taraxaci 15 parts, Cortex Jujubae 7 parts, Radix Et Rhizoma Rhei 25 parts, Flos Lonicerae 4.5 parts, Herba Galii Teneri 12 parts, sky steeps
Son 3.0 parts, Radix Sophorae Flavescentis 10 parts.
The preparation method of above-mentioned wiping agent, step is:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 5 hours, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls and treats
With；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 3 hours, the consumption of white vinegar is 4 times of Herba portulacae and Flos Lonicerae weight, takes
Go out repeatedly to stir-fry with slow fire 6 minutes, take out to dry and grind to form smalls to cross 100 mesh sieves stand-by；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 30 minutes every time, and twice filtrate merges, concentrated juice paste, add
Enter 2 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in less than 50 DEG C and be dried i.e.
Obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 10 minutes, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add mixture weight 3 times light salt brine, put in water-bath heat, be stirred continuously and make
Mixture dissolves, and i.e. obtains wiping agent after cooling.
Experimental example purpose is to verify whether this wiping agent has curative effect to treatment neonatal dacryocystitis.
Being diagnosis basis according to " the new Chinese medicine guideline of clinical investigations " that Ministry of Public Health is formulated for 1993, totally 200 examples are new
Raw youngster dacryocystisis patient, random division is administration group and matched group.
Using method: with the special cotton swab of baby, pick a small amount of wiping agent, when child sleep soundly, wiping eyes gently
Surrounding, twice on the one.
Criterion of therapeutical effect: effective: common sympton alleviates substantially is invalid: malaise symptoms is the most unchanged.
One day before the experiments, the health of record patient, look over patient body symptom every day, it is ensured that be administered
Group and matched group situation are basically identical.Administration group eats this product embodiments 5 gained wiping agent every day, checks patient body every day
Situation, makes a record.Result such as table 1 below:
Table 1:
Efficacy analysis: when administration group (wiping agent of the present invention) uses 1 day, most patient sensory symptoms substantially alleviates, and affected part is obvious
Feeling to take a favorable turn, patient's emotion takes a turn for the better, and during medication 2 days, patient is almost recovered, and drug withdrawal a period of time has no that repeatedly, the state of an illness obtains relatively
Good control.After matched group is taken medicine, curative effect is obvious, but after drug withdrawal, the patient of 94% is recurred again.
Clinical tests prove that, wiping agent of the present invention is on treatment neonatal dacryocystitis, and effective percentage is 98%, and cure rate is
95%, exceed 28% than oral western medicine effective percentage, cure rate exceeds 20%, and can thoroughly remove old complaint, makes real the fullying recover from an illness of patient
More；And the health of patient will not be caused any burden.Wiping agent instant effect of the present invention, it is possible to reach to alleviate rapidly patient painful
Purpose, and relapse rate is low, is a kind of wiping agent safely and effectively treating neonatal dacryocystitis.
Claims (10)
1. the wiping agent treating neonatal dacryocystitis, it is characterised in that: take off state weight proportion primary raw material preparation and
Become: Rhizoma Arisaematis 1.0-2.0 part, Fructus Ligustri Lucidi 3-5 part, Fructus Leonuri 1-5 part, Herba portulacae 4-6 part, Herba Taraxaci 10-20 part, Cortex Jujubae 5-
10 parts, Radix Et Rhizoma Rhei 20-30 part, Flos Lonicerae 3-6 part, Herba Galii Teneri 10-15 part, Herba seu Fructus Physalis Minimae 2.5-3.5 part, Radix Sophorae Flavescentis 8-12 part.
The wiping agent for the treatment of neonatal dacryocystitis the most according to claim 1, it is characterised in that: take off and state weight proportion
Primary raw material is prepared from: Rhizoma Arisaematis 1.3-1.8 part, Fructus Ligustri Lucidi 3.5-4.5 part, Fructus Leonuri 2-4 part, Herba portulacae 4.5-5.5 part,
Herba Taraxaci 13-18 part, Cortex Jujubae 6-8 part, Radix Et Rhizoma Rhei 23-28 part, Flos Lonicerae 4-5 part, Herba Galii Teneri 11-14 part, Herba seu Fructus Physalis Minimae 2.8-3.3
Part, Radix Sophorae Flavescentis 9-11 part.
The wiping agent for the treatment of neonatal dacryocystitis the most according to claim 1, it is characterised in that: take off and state weight proportion
Primary raw material is prepared from: Rhizoma Arisaematis 1.5 parts, Fructus Ligustri Lucidi 4 parts, Fructus Leonuri 3 parts, Herba portulacae 5 parts, Herba Taraxaci 15 parts, Cortex Jujubae 7
Part, Radix Et Rhizoma Rhei 25 parts, Flos Lonicerae 4.5 parts, Herba Galii Teneri 12 parts, Herba seu Fructus Physalis Minimae 3.0 parts, Radix Sophorae Flavescentis 10 parts.
4., according to the preparation method of the wiping agent treating neonatal dacryocystitis described in any one of claim 1-3, its feature exists
In: step is as follows:
1. Cortex Jujubae is cleaned, even with yellow wine spray, stand 3-7 hour, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls
Stand-by；
2. Herba portulacae and Flos Lonicerae white vinegar being soaked 2-4 hour, taking-up slow fire stir-fries 4-8 minute repeatedly, takes out to dry and grinds
Wearing into smalls, to cross 80-120 mesh sieve stand-by；
3. Herba Taraxaci is made coarse powder, and water carries twice, boils 20-40 minute every time, and twice filtrate merges, concentrated juice paste,
(1:5), add 1-3 times amount ethanol, be sufficiently stirred for, washing, put and separate on buchner funnel, discard ethanol mother liquor, be deposited in 50 DEG C
Below it is drying to obtain rough water extract dry powder；
4. Rhizoma Arisaematis, Fructus Ligustri Lucidi, Fructus Leonuri, Radix Et Rhizoma Rhei, Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Radix Sophorae Flavescentis are smashed and be together placed in crock, little fire
Slow baking 8-12 minute, grinds to form smalls and sieves stand-by；
5. by step 1.-4. gains mixing, add the light salt brine of mixture weight 2-4 times, put in water-bath heating, be stirred continuously
Make mixture dissolve, after cooling, i.e. obtain wiping agent.
Preparation method the most according to claim 4, it is characterised in that: 1. Cortex Jujubae is cleaned by step, even with yellow wine spray, quiet
Put 4-6 hour (preferably being cleaned by Cortex Jujubae, spray even with yellow wine, stand 5 hours).
Preparation method the most according to claim 4, it is characterised in that: the consumption of step 2. white vinegar is Herba portulacae and Flos Lonicerae
Weight 3-5 times (preferably, the consumption of white vinegar is Herba portulacae and 3.5-4.5 times of Flos Lonicerae weight, the most preferably, white vinegar
Consumption be 4 times of Herba portulacae and Flos Lonicerae weight).
Preparation method the most according to claim 4, it is characterised in that: 2. step soaks 2.5-3.5 hour with white vinegar, takes out
Repeatedly stir-fry 5-7 minute (preferably soaking 3 hours with white vinegar, taking-up slow fire stir-fries 6 minutes repeatedly) with slow fire.
Preparation method the most according to claim 4, it is characterised in that: 3. Herba Taraxaci is made coarse powder by step, and water carries twice,
Boil 25-35 minute (the most 3. Herba Taraxaci being made coarse powder, water carries twice, boils 30 minutes every time) every time.
Preparation method the most according to claim 4, it is characterised in that: the least fire of step dries 9-11 minute (the least fire slowly
Slow baking 10 minutes).
Preparation method the most according to claim 4, it is characterised in that: 5. step adds mixture weight 2.5-3.5 times
Light salt brine (is preferably added to the light salt brine of mixture weight 3 times).
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Application publication date: 20161109 |