CN104721348A - Traditional Chinese medicine decoction for treating acute dacryocystitis and preparation method thereof - Google Patents
Traditional Chinese medicine decoction for treating acute dacryocystitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine decoction for treating acute dacryocystitis. The traditional Chinese medicine decoction is prepared from the following main raw materials in parts by weight: 1-5 parts of calamine, 6-12 parts of mulberry, 5-15 parts of the seed of Chinese dodder, 6-16 parts of tropic ageratum herb, 2-4 parts of semen cassiae, 5-13 parts of glossy privet fruit, 10-20 parts of pepper, 8-20 parts of astaxanthin, 7-14 parts of wild chrysanthemum flower, 4-8 parts of horsetail, 8-14 parts of honeysuckle, and 6-15 parts of root of common peony. The traditional Chinese medicine decoction disclosed by the invention is based on the principle for treating acute dacryocystitis by using traditional Chinese medicines; the selected traditional Chinese medicines have the effects of sterilizing, relieving itching and diminishing inflammation; the symptoms of acute dacryocystitis of users can be rapidly relieved; furthermore, the cost is low; if the traditional Chinese medicine decoction is used for a long time, economical burden of patients cannot be caused; and the traditional Chinese medicine decoction is an ideal drug for treating acute dacryocystitis.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of Chinese medicine decoction for the treatment of acute dacryocystitis and preparation method thereof.
Background technology
Acute dacryocystitis is many to be changed by chronic dacryocystitis, but also has and start to be acute former bacteriological infection person.Common causative microorganism has Diplococcus pneumoniae, staphylococcus aureus, beta hemolytic streptococcus, influenza virus etc.Acute dacryocystitis can occur suddenly without on the basis of obstructed lacrimal passage, also can have dacryocanalicular obstruction due to the same fashion of obstruction of naso lacrimal duct, purulent secretion can not be discharged, or occur on the basis of chronic dacryocystitis, caused by secondary infection.Clinical manifestation: often have chronic dacryocystitis history; Lachrymal sac portion height is red, swollen, hot, bitterly, severe one homonymy face nose is red and swollen, before ear and submandibular lymph nodes enlargement, tenderness, companion body temperature rise, general malaise; Egilops skin can form lacrimal sac fistula.Differential Diagnosis: should differentiate mutually with the angioneurotic edema etc. in eyelid abscess, lid cellulitis, hordeolum, lachrymal sac portion.And lacrimal sac flushing can be unblocked.And other various diseases have again its principal character, therefore general diagnostic is not difficult.Conventional therapeutic modality: partial hot compressing or painting YUSHIZHI RUANGAO.Give sulfonamides, antibiotic etc treatment.Removing lachrymal sac focus of infection, sets up Endonasal drainage passage, is the basic principle for the treatment of.The various antibiotic ophthalmic liquid of Drug therapy Topical, 3 ~ 4 times/day, extrude emptying lachrymal sac endocrine before dripping medicine, medicinal liquid just can be inhaled into lachrymal sac; Whole body sulfanilamide or antibiotic, purulent secretion can disappear, but can not unblocking and retention, as preoperative preparation.Irrigation of lacrimal passage is in order to thoroughly remove purulence or mucus secretions, and after can rinsing well with normal saline flushing lachrymal sac pus, reinject 0.3 ~ 0.5ml antibiotic.Adopt antibiotic adrenocortical hormone and fibrinolysin mixed liquor to rinse, good curative effect can be had for the obstruction that there is no fixing shape cicatrix in early days.Obstructive position, the patient at nasolacrimal duct place, can consider that lacrimal passage intubation is performed the operation.First lacrimal passage probing, then carry out tear duct dilating, and insert tear stains.Topical intranasal mucosa and lachrymal sac are passed through, together with surgical stapling, to set up the passage of a drain tear.Should according to circumstances select its indication: atrophic rhinitis, lupus, tuberculosis, syphilitic, dacryopericystitis's disease or sieve hole suppurative inflammation, malignant tumor, Corneal inflammation, interior ophthalmia, first ocular injury etc. should consider that lachrymal sac is extractd.
In the invention of existing treatment acute dacryocystitis, Authorization Notice No. CN102366561 A(application number 201110295031.0) Chinese patent disclose a kind of Chinese herbal medicine for the treatment of chronic dacryocystitis: Radix Bupleuri 15-25 parts; Radix Scutellariae 25-35 parts; Rhizoma Coptidis 15-25 parts; Fructus Gardeniae 15-25 parts; Rhizoma Cimicifugae 15-20 parts; Herba Violae 10-15 parts; Semen Cassiae 10-20 parts; Fructus Forsythiae 10-20 parts; Herba Lophatheri 15-25 parts; Poria 15-25 parts; Herba Hieracii Umbellati 10-15 parts; Radix Ilicis Pubescentis 15-20 parts; Radix Gentianae 15-25 parts; Semen Celosiae 10-15 parts; Herba violae patrinii 10-15 parts; YEXIAHONG 10-15 parts; Herba Lobeliae Chinensis 15-20 parts; Herba Dendrobii 20-30 parts; Concha Haliotidis 10-15 part; Du Testudinis dish 10-15 parts; Add water 2000 parts, put into pottery pot boiled after, slow fire boiling 20-30 minutes.Authorization Notice No. CN101152354 A(200710132972.6) Chinese patent disclose a kind of Chinese medicine for the treatment of acute dacryocystitis, its composition: Flos Lonicerae 25 grams, Herba Taraxaci 25 grams, Herba Violae 25 grams, Radix Semiaquilegiae 25 grams; Auxiliary prescription: constipation person adds each 15 grams of Rhizoma Coptidis, Herba Equiseti Hiemalis; Red and swollen obviously person adds each 15 grams of Cortex Moutan, Radix Paeoniae Rubra.
As can be seen here, Chinese medicine occupies the status of very Chinese medicine in acute dacryocystitis preparing, but in existing technology, great majority are external-use lotion and collyrium, has with high costs, not easily the of a specified duration defect such as use.
Summary of the invention
For the present situation of existing treatment acute dacryocystitis deficiency, an object of the present invention is to provide a kind of Chinese medicine decoction for the treatment of acute dacryocystitis, there is feature that is easy to operate, evident in efficacy, that have no side effect, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of the Chinese medicine decoction of above-mentioned treatment acute dacryocystitis.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine decoction for acute dacryocystitis, take off the primary raw material stating weight proportion and be prepared from: Calamina 1-5 part, Fructus Mori 6-12 part, Semen Cuscutae 5-15 part, Herba Agerati Conyzoidis 6-16 part, Semen Cassiae 2-4 part, Fructus Ligustri Lucidi 5-13 part, Pericarpium Zanthoxyli 10-20 part, astaxanthin 8-20 part, Flos Chrysanthemi Indici 7-14 part, Herba Equiseti Hiemalis 4-8 part, Flos Lonicerae 8-14 part, Radix Paeoniae Rubra 6-15 part.
Treat a Chinese medicine decoction for acute dacryocystitis, optimum ratio, take off the primary raw material stating weight proportion and be prepared from: Calamina 2-4 part, Fructus Mori 8-10 part, Semen Cuscutae 8-13 part, Herba Agerati Conyzoidis 10-12 part, Semen Cassiae 2.5-3.5 part, Fructus Ligustri Lucidi 8-10 part, Pericarpium Zanthoxyli 13-18 part, astaxanthin 12-16 part, Flos Chrysanthemi Indici 9-12 part, Herba Equiseti Hiemalis 5-7 part, Flos Lonicerae 10-12 part, Radix Paeoniae Rubra 9-11 part.
Treat a Chinese medicine decoction for acute dacryocystitis, better preferred proportioning, take off the primary raw material stating weight proportion and be prepared from: Calamina 3 parts, Fructus Mori 9 parts, Semen Cuscutae 11.5 parts, Herba Agerati Conyzoidis 11 parts, Semen Cassiae 3 parts, Fructus Ligustri Lucidi 9 parts, 15 parts, Pericarpium Zanthoxyli, astaxanthin 14 parts, Flos Chrysanthemi Indici 10.5 parts, Herba Equiseti Hiemalis 6 parts, Flos Lonicerae 11 parts, Radix Paeoniae Rubra 10 parts.
The preparation method of above-mentioned treatment acute dacryocystitis Chinese medicine decoction, step is as follows:
(1) by Calamina and Semen Cassiae cleaning 1-5 time, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with Pericarpium Zanthoxyli 2-4 white vinegar doubly, soak 50-70 minute, add white vinegar weight 4-6 clear water doubly, heating 20-40 minute, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun under being placed in daylight 5-7 days, and it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, after boiling 2-7 minute, filter, obtain filtrate 1, filtering residue 60-90% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added the mid-water-bath of step (3) gained mixed liquor heats 10-20 minute after add astaxanthin, after astaxanthin melting, stop heating, fully stir 3-6 minute, ultraviolet sterilization 3-7 minute, bottle and get final product.
The preparation method of above-mentioned Chinese medicine decoction, step (1) is by Calamina and Semen Cassiae cleaning 2-4 time (preferred, Calamina and Semen Cassiae are cleaned 3 times).
The preparation method of above-mentioned Chinese medicine decoction, step (2), with Pericarpium Zanthoxyli 2.5-3.5 white vinegar doubly, is soaked 55-65 minute (preferred, with the white vinegar of 3 times, Pericarpium Zanthoxyli, to soak 60 minutes).
The preparation method of above-mentioned Chinese medicine decoction, step (2) adds white vinegar weight 4.5-5.5 clear water doubly, heats 25-35 minute (preferred, to add the clear water of white vinegar weight 5 times, heat 30 minutes).
The preparation method of above-mentioned Chinese medicine decoction, step (3) big fire decocts to boiling, after boiling 3-6 minute, filters (preferred, big fire decocts to boiling, until boiling after 5 minutes, filters).
The preparation method of above-mentioned Chinese medicine decoction, step (3) filtering residue 70-80% ethanol extraction 3 times (preferably, filtering residue 75% ethanol extraction 3 times).
The preparation method of above-mentioned Chinese medicine decoction, adds astaxanthin (preferred, the mid-water-bath of gained mixed liquor to be heated after 15 minutes and add astaxanthin) after the mid-water-bath of step (4) gained mixed liquor heats 13-18 minute.
Using method: for making the present invention reach optimum therapeuticing effect, the decoction prepared, is divided into two, a oral after breakfast, lunch and dinner, the cleaning of another part or wiping eyes.
Treat a Chinese medicine decoction for acute dacryocystitis, the pharmacological effect of each crude drug is respectively:
Calamina: base is former: be carbonate calcite race's minerals smithsonite or carbonate mineral marionite.Composition: 1. Calamina is mainly old is zinc carbonate, still containing small amounts calcium 0.27%, magnesium oxide 0.45%, ferrum oxide 0.58%, manganese oxide 0.01%.Wherein zinc is often by a small amount of ferrum (bivalence) is replaced.What have still contains a small amount of cobalt, copper, cadmium, lead etc.2. Calamina main component of swimming is basic zinc carbonate, and leaded, the magazine such as cadmium, magnesium, ferrum, aluminum.The property of medicine: sweet, flat.Return liver, spleen, lung meridian.Function cures mainly: improving eyesight removing nebula, and removing dampness is antipruritic, expelling pus and promoting granulation.Cure mainly conjunctival congestion and swelling pain, marginal blepharitis eye, many tear photophobia, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, skin eczema, pudendum pruritus due to damp pathogen.
Fructus Mori: base is former: be the dry fruit ear of Moraceae Mulberry plant Mulberry.Composition: fruit ear is containing vitamin B1, B2 and carotene; The fatty acid of its lipid is mainly linoleic acid, oleic acid, palmitic acid, stearic acid, and there still have to be sad on a small quantity, n-nonanoic acid, capric acid etc.The property of medicine: sweet, sour, cold.Return sweet, kidney channel.Function cures mainly: nourishing YIN and benefiting blood, promotes the production of body fluid, intestine moistening.Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, insomnia, quenches one's thirst, the soreness of waist, dryness of the intestine constipation, tinea alba.
Semen Cuscutae: base is former: be the herb of Convolvulaceae Hellweed Semen Cuscutae.Composition: Semen Cuscutae is containing alkaloid, anthraquinone, coumarin, flavone, glycoside, sterol, tannic acid, saccharide etc.Flavonoid has: Quercetin, astragalin, hyperin; Sterols has: cholesterol, campesterol, cupreol, stigmasterol, β-Amyrin.Also trace element is contained as strontium, molybdenum, calcium, magnesium, ferrum, manganese, zinc, copper etc. and several amino acids (free amino acid in seed and the total amino acids after being hydrolyzed are 5.3%, and wherein the content of essential amino acids accounts for 42.8%).The property of medicine: micro-pungent, sweet, flat, nontoxic.Function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Herba Agerati Conyzoidis: be the herb of Compositae Ageratum plant Ageratum conyzoides.Composition: herb contains flavonoid, alkaloid, triterpenoid compound, volatile oil.Aerial parts I have chromene class.Pharmacology: have stimulation to cardiac muscle, has inhibitory action to smooth muscle, has the effect of anti-inflammatory and antalgic, has antibacterial effect.The property of medicine: micro-hardship, pungent, cool.Function cures mainly: heat-clearing and toxic substances removing, hemostasis, pain relieving.
Semen Cassiae: Semen Cassiae bitter in the mouth, sweet, salty, cold nature, enters liver, kidney, large intestine channel; Loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, has laxative action, reducing blood pressure and blood fat.
Fructus Ligustri Lucidi: base is former: be the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi.Composition: fruit is containing triterpenes: oleanolic acid, acetyloleanolic acid, ursolic acid, acetyl ursolic acid; Phenolic glycoside class: p-hydroxyphenylethanol, Hydroxytyrosol, nuzhenide, oleuropein, Fructus Ligustri Lucidi fruit glycosides, Fructus Ligustri Lucidi acid, Fructus Ligustri Lucidi thuja acid etc.The property of medicine: sweet, bitter, cold.Return liver, kidney channel.Function cures mainly: liver and kidney tonifying, clearind deficient heat you, improving eyesight.Cure mainly Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.
Pericarpium Zanthoxyli: return spleen, stomach, kidney channel.Effect warming middle-JIAO to relieve pain, killing parasites for relieving itching.Cure mainly for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation; External: eczema, pudendal pruritus.
Astaxanthin: astaxanthin has multiple physiological function, as at non-oxidizability, antitumor, prophylaxis of cancer, enhancing immunity, improve in vision etc. and have certain effect.
Flos Chrysanthemi Indici: the leaf of Herba Dendranthematis indici, flower and all herbal medicine.Bitter in the mouth, pungent, cool, heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, dissipating blood stasis, improving eyesight, blood pressure lowering.Prevent and treat epidemic cerebrospinal meningitis, prevention influenza, flu, treatment hypertension, hepatitis, dysentery, carbuncle furuncle treatment skin ulcer have positive effect.The immersion of Flos Chrysanthemi Indici is to killing wriggler and fly larvae is also very effective.
Herba Equiseti Hiemalis: base is former: be the herb of Equisetaceae horse-tail Herba Equiseti Hiemalis.Composition: aerial parts is containing volatile oil, wherein fatty acid: succinic acid, Fumaric acid, 1,3-propanedicarboxylic acid methyl ester, P-hydroxybenzoic acid, m-hydroxybenzoic acid, ferulic acid, vanillic acid, caffeic acid etc.The property of medicine: sweet, micro-hardship, flat.Return lung, liver, gallbladder meridian.Function cures mainly: wind-dispelling heat-dissipating, improving acuity of vision and removing nebula, hemostasis.Cure mainly wind heat conjunctival congestion, the raw nebula of order, epiphora induced by wind, discharging fresh blood stool, hemorrhoidal bleeding, dysentery, married woman's metrorrhagia, proctoptosis.
Flos Lonicerae: Flos Lonicerae, having another name called Radix Ophiopogonis " Flos Lonicerae " one comes from Compendium of Material Medica, owing to opening as white at the beginning of Flos Lonicerae, after transfer yellow to, hence obtain one's name Flos Lonicerae.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or is with the flower just opened.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.Resisting pathogenic microbes effect: experiment in vitro shows, flower and rattan to various pathogens as staphylococcus aureus, Hemolytic streptococcus, escherichia coli, dysentery bacterium, vibrio cholera, Bacillus typhi, Salmonella paratyphi etc. all have certain inhibitory action, also effective to streptococcus pneumoniae, meningococcus, bacillus pyocyaneus, tubercule bacillus.
Radix Paeoniae Rubra: for thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Radix Paeoniae Rubra (parched): after frying, the property of medicine relatively relaxes, promoting blood circulation and stopping pain and not damaging the spleen and stomach, can be used for the stagnant pain of the stasis of blood.Wine Radix Paeoniae Rubra: with promoting blood circulation to remove blood stasis power victory, clearing away heat and cooling blood effect is more weak.Be used for amenorrhea or dysmenorrhea, traumatic injury.
Chinese medicine decoction of the present invention is based on the principle of traditional Chinese medical herbal treatment acute dacryocystitis.The Chinese medicinal material selected has effect of sterilization, antipruritic, antiinflammatory, can the symptom of rapid recovery user acute dacryocystitis, and cheap, and life-time service also can not cause the financial burden of patient, is the ideal medicine for the treatment of acute dacryocystitis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1one treats acute dacryocystitis Chinese medicine decoction, takes off and states raw material of Chinese medicine medicine (getting 20g for every part): Calamina 1 part, Fructus Mori 6 parts, Semen Cuscutae 5 parts, Herba Agerati Conyzoidis 6 parts, Semen Cassiae 2 parts, Fructus Ligustri Lucidi 5 parts, 10 parts, Pericarpium Zanthoxyli, astaxanthin 8 parts, Flos Chrysanthemi Indici 7 parts, Herba Equiseti Hiemalis 4 parts, Flos Lonicerae 8 parts, Radix Paeoniae Rubra 6 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is:
(1) Calamina and Semen Cassiae are cleaned 1 time, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 80 mesh sieves stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with the white vinegar of 2 times, Pericarpium Zanthoxyli, soak 50 minutes, add the clear water of white vinegar weight 4 times, heat 20 minutes, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun 5 days under being placed in daylight, it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, until boiling after 2 minutes, filter, obtain filtrate 1, filtering residue 60% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added heating in the mid-water-bath of step (3) gained mixed liquor and add astaxanthin after 10 minutes, after astaxanthin melting, stop heating, fully stir 3 minutes, ultraviolet sterilization 3 minutes, bottles and get final product.
model case oneliu XX, female, 24 years old, university students, closely used mobile phone for a long time, unhygienic with eye.One day, Zhao's eye has pain, rubs rear eye shed tears incessantly with hands, Zhao did not seek medical advice in time at that time, there is the phenomenon of edema in Ji Tian later Chao Dynasty lachrymal sac position, eye visual deterioration, and infect rubescent, the symptom aggravation that eye is shed tears, and with the symptom of fever, go to see a doctor subsequently, diagnosis is acute dacryocystitis, under the suggestion of doctor, sufferer has taken the Chinese medicine decoction obtained by the present invention.
Take the decoction adding and use gained in embodiment 1, take the same day, the ocular pain sense of sufferer obviously reduces, and eye edema takes a turn for the better to some extent, after taking 3 days, the edema at lachrymal sac place disappears, and the symptom that eye is shed tears is cured, and vision starts to recover, ocular infection redness disappears, after taking 5 days, the acute dacryocystitis symptom of patient arrived basic healing, eye returns to normal condition.
embodiment 2one treats acute dacryocystitis Chinese medicine decoction, takes off and states raw material of Chinese medicine medicine (getting 20g for every part) Calamina 5 parts, Fructus Mori 12 parts, Semen Cuscutae 15 parts, Herba Agerati Conyzoidis 16 parts, Semen Cassiae 4 parts, Fructus Ligustri Lucidi 13 parts, 20 parts, Pericarpium Zanthoxyli, astaxanthin 20 parts, Flos Chrysanthemi Indici 14 parts, Herba Equiseti Hiemalis 8 parts, Flos Lonicerae 14 parts, Radix Paeoniae Rubra 15 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is:
(1) Calamina and Semen Cassiae are cleaned 5 times, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 120 mesh sieves stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with the white vinegar of 4 times, Pericarpium Zanthoxyli, soak 70 minutes, add the clear water of white vinegar weight 6 times, heat 40 minutes, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun 7 days under being placed in daylight, it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, until boiling after 7 minutes, filter, obtain filtrate 1, filtering residue 90% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added heating in the mid-water-bath of step (3) gained mixed liquor and add astaxanthin after 20 minutes, after astaxanthin melting, stop heating, fully stir 6 minutes, ultraviolet sterilization 7 minutes, bottles and get final product.
embodiment 3one treats acute dacryocystitis Chinese medicine decoction, takes off and states raw material of Chinese medicine medicine (getting 20g for every part): Calamina 2 parts, Fructus Mori 8 parts, Semen Cuscutae 8 parts, Herba Agerati Conyzoidis 10 parts, Semen Cassiae 2.5 parts, Fructus Ligustri Lucidi 8 parts, 13 parts, Pericarpium Zanthoxyli, astaxanthin 12 parts, Flos Chrysanthemi Indici 9 parts, Herba Equiseti Hiemalis 5 parts, Flos Lonicerae 10 parts, Radix Paeoniae Rubra 9 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is:
(1) Calamina and Semen Cassiae are cleaned 2 times, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 90 mesh sieves stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with the white vinegar of 2.5 times, Pericarpium Zanthoxyli, soak 55 minutes, add the clear water of white vinegar weight 4.5 times, heat 25 minutes, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun 5 days under being placed in daylight, it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, until boiling after 3 minutes, filter, obtain filtrate 1, filtering residue 70% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added heating in the mid-water-bath of step (3) gained mixed liquor and add astaxanthin after 13 minutes, after astaxanthin melting, stop heating, fully stir 4 minutes, ultraviolet sterilization 4 minutes, bottles and get final product.
model case twozou XX, female, 48 years old, chemical plant financial executive, is in chemical reagent contaminated environment, originally due to work under bad environment for a long time, eye causes infection, suffers from chronic dacryocystitis, among the disease being in chronic dacryocystitis for a long time, one day, sufferer eyes are rubescent, the blood vessel enlargement at lachrymal sac place, and ceaselessly shed tears, go to see a doctor, diagnosis is acute dacryocystitis.
Take the decoction adding and use gained in embodiment 3, take the Chinese medicine decoction same day that the present invention obtains, the symptom that eye is shed tears is clearly better, take after 5, the blood vessel detumescence of sufferer lachrymal sac place, the symptom that the infection of eyes is rubescent is also fully recovered, after taking 7 days, the disease of sufferer is all cured, because the ophthalmic uncomfortable sense of the initiation of chronic dacryocystitis also makes moderate progress.
embodiment 4one treats acute dacryocystitis Chinese medicine decoction, takes off and states raw material of Chinese medicine medicine (getting 20g for every part): Calamina 4 parts, Fructus Mori 10 parts, Semen Cuscutae 13 parts, Herba Agerati Conyzoidis 12 parts, Semen Cassiae 3.5 parts, Fructus Ligustri Lucidi 10 parts, 18 parts, Pericarpium Zanthoxyli, astaxanthin 16 parts, Flos Chrysanthemi Indici 12 parts, Herba Equiseti Hiemalis 7 parts, Flos Lonicerae 12 parts, Radix Paeoniae Rubra 11 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is:
(1) Calamina and Semen Cassiae are cleaned 4 times, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 110 mesh sieves stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with the white vinegar of 3.5 times, Pericarpium Zanthoxyli, soak 65 minutes, add the clear water of white vinegar weight 5.5 times, heat 35 minutes, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun 7 days under being placed in daylight, it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, until boiling after 6 minutes, filter, obtain filtrate 1, filtering residue 80% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added heating in the mid-water-bath of step (3) gained mixed liquor and add astaxanthin after 18 minutes, after astaxanthin melting, stop heating, fully stir 5 minutes, ultraviolet sterilization 6 minutes, bottles and get final product.
embodiment 5one treats acute dacryocystitis Chinese medicine decoction, takes off and states raw material of Chinese medicine medicine (getting 20g for every part): Calamina 3 parts, Fructus Mori 9 parts, Semen Cuscutae 11.5 parts, Herba Agerati Conyzoidis 11 parts, Semen Cassiae 3 parts, Fructus Ligustri Lucidi 9 parts, 15 parts, Pericarpium Zanthoxyli, astaxanthin 14 parts, Flos Chrysanthemi Indici 10.5 parts, Herba Equiseti Hiemalis 6 parts, Flos Lonicerae 11 parts, Radix Paeoniae Rubra 10 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is:
(1) Calamina and Semen Cassiae are cleaned 3 times, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 100 mesh sieves stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with the white vinegar of 3 times, Pericarpium Zanthoxyli, soak 60 minutes, add the clear water of white vinegar weight 5 times, heat 30 minutes, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun 6 days under being placed in daylight, it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, until boiling after 5 minutes, filter, obtain filtrate 1, filtering residue 75% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added heating in the mid-water-bath of step (3) gained mixed liquor and add astaxanthin after 15 minutes, after astaxanthin melting, stop heating, fully stir 4.5 minutes, ultraviolet sterilization 5 minutes, bottles and get final product.
experimental example:the clinical practice of embodiment 5 gained treatment acute dacryocystitis Chinese medicine decoction: screen 400 routine patients in 10 hospitals, selected scope: the people having acute dacryocystitis, before test 1 day, Continuous Observation is carried out to this crowd, record symptom and change, experimental group 200 people, matched group 200 people, experimental group uses gained Chinese medicine decoction of the present invention, and matched group uses the cured substance of other treatment acute dacryocystitis: after using this product, and malaise symptoms disappears; Effective: after using this product, malaise symptoms disappears substantially; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
table 1:
| Experimental group | Matched group | |
| Number of cases | 200 | 200 |
| Cure number of cases | 192 | 160 |
| Effective number of cases | 6 | 10 |
| Invalid number of cases | 2 | 30 |
| Total effective rate | 99% | 85% |
Take period self-induction symptom and physical change of spirit as shown in table 2.
Table 2:
Prove through clinical trial, Chinese medicine decoction of the present invention is to acute dacryocystitis Be very effective, total effective rate is 99%, general patient just can have significant curative effect in 3 days in use, and Chinese medicine decoction multiselect of the present invention with can heat-clearing and toxic substances removing, can carry out antipruritic, Aloe Extract and antibacterial fast, a kind of Chinese medicine decoction for the treatment of acute dacryocystitis, wherein monarch drug is: Herba Agerati Conyzoidis, astaxanthin, Pericarpium Zanthoxyli, Radix Paeoniae Rubra and Semen Cuscutae, and ministerial drug is Fructus Mori and Flos Chrysanthemi Indici, and Fructus Ligustri Lucidi, Herba Equiseti Hiemalis are adjuvant drug.Monarch drug carries attending effectiveness in the present invention; Ministerial drug is the medicine that auxiliary monarch drug strengthens the main disease for the treatment of and main symptom; Adjuvant drug treatment is held concurrently disease, slows down the strong of monarch drug and ministerial drug; Residual drug, as making medicine, plays a part guiding drug.
Claims (10)
1. treat a Chinese medicine decoction for acute dacryocystitis, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Calamina 1-5 part, Fructus Mori 6-12 part, Semen Cuscutae 5-15 part, Herba Agerati Conyzoidis 6-16 part, Semen Cassiae 2-4 part, Fructus Ligustri Lucidi 5-13 part, Pericarpium Zanthoxyli 10-20 part, astaxanthin 8-20 part, Flos Chrysanthemi Indici 7-14 part, Herba Equiseti Hiemalis 4-8 part, Flos Lonicerae 8-14 part, Radix Paeoniae Rubra 6-15 part.
2. the Chinese medicine decoction for the treatment of acute dacryocystitis according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Calamina 2-4 part, Fructus Mori 8-10 part, Semen Cuscutae 8-13 part, Herba Agerati Conyzoidis 10-12 part, Semen Cassiae 2.5-3.5 part, Fructus Ligustri Lucidi 8-10 part, Pericarpium Zanthoxyli 13-18 part, astaxanthin 12-16 part, Flos Chrysanthemi Indici 9-12 part, Herba Equiseti Hiemalis 5-7 part, Flos Lonicerae 10-12 part, Radix Paeoniae Rubra 9-11 part.
3. the Chinese medicine decoction for the treatment of acute dacryocystitis according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Calamina 3 parts, Fructus Mori 9 parts, Semen Cuscutae 11.5 parts, Herba Agerati Conyzoidis 11 parts, Semen Cassiae 3 parts, Fructus Ligustri Lucidi 9 parts, 15 parts, Pericarpium Zanthoxyli, astaxanthin 14 parts, Flos Chrysanthemi Indici 10.5 parts, Herba Equiseti Hiemalis 6 parts, Flos Lonicerae 11 parts, Radix Paeoniae Rubra 10 parts.
4. the preparation method of the treatment acute dacryocystitis Chinese medicine decoction according to any one of claim 1-3, is characterized in that: step is as follows:
(1) by Calamina and Semen Cassiae cleaning 1-5 time, towel off clean, tie down Calamina and Semen Cassiae with iron wire, it is crisp to be placed in fire door forging, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve stand-by;
(2) cleaned by Pericarpium Zanthoxyli, be placed in crock, with Pericarpium Zanthoxyli 2-4 white vinegar doubly, soak 50-70 minute, add white vinegar weight 4-6 clear water doubly, heating 20-40 minute, taken out by Pericarpium Zanthoxyli with strainer, be exposed to the sun under being placed in daylight 5-7 days, and it is stand-by to grind to form smalls, and filtrate is for subsequent use;
(3) Fructus Mori, Semen Cuscutae, Herba Agerati Conyzoidis, Fructus Ligustri Lucidi, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Flos Lonicerae and Radix Paeoniae Rubra are joined in step (2) gained filtrate, big fire decocts to boiling, after boiling 2-7 minute, filter, obtain filtrate 1, filtering residue 60-90% ethanol extraction 3 times, 2 hours first times, remaining twice 1 hour, merge alcohol extract and mix with filtrate 1, obtaining mixed liquor;
(4) step (1), (2) gained smalls are added the mid-water-bath of step (3) gained mixed liquor heats 10-20 minute after add astaxanthin, after astaxanthin melting, stop heating, fully stir 3-6 minute, ultraviolet sterilization 3-7 minute, bottle and get final product.
5. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (1) is by Calamina and Semen Cassiae cleaning 2-4 time (preferred, Calamina and Semen Cassiae are cleaned 3 times).
6. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (2), with Pericarpium Zanthoxyli 2.5-3.5 white vinegar doubly, is soaked 55-65 minute (preferred, with the white vinegar of 3 times, Pericarpium Zanthoxyli, to soak 60 minutes).
7. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (2) adds white vinegar weight 4.5-5.5 clear water doubly, heats 25-35 minute (preferred, to add the clear water of white vinegar weight 5 times, heat 30 minutes).
8. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (3) big fire decocts to boiling, after boiling 3-6 minute, filters (preferred, big fire decocts to boiling, until boiling after 5 minutes, filters).
9. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (3) filtering residue 70-80% ethanol extraction 3 times (preferred, filtering residue 75% ethanol extraction 3 times).
10. the preparation method of Chinese medicine decoction according to claim 4, it is characterized in that: after the mid-water-bath of step (4) gained mixed liquor heats 13-18 minute, add astaxanthin (preferred, the mid-water-bath of gained mixed liquor to be heated after 15 minutes and add astaxanthin).
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Application publication date: 20150624 |