CN106074238B - A kind of Golden flower whitening and spot eliminating cream and preparation method thereof - Google Patents

A kind of Golden flower whitening and spot eliminating cream and preparation method thereof Download PDF

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CN106074238B
CN106074238B CN201610416398.6A CN201610416398A CN106074238B CN 106074238 B CN106074238 B CN 106074238B CN 201610416398 A CN201610416398 A CN 201610416398A CN 106074238 B CN106074238 B CN 106074238B
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extract
golden flower
whitening
alcohol
eliminating cream
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CN106074238A (en
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王飞
王一飞
王闯
马婧
王巧利
任哲
王林涛
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Guangzhou Jinan Biomedicine Research and Development Base Co Ltd
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Guangzhou Jinan Biomedicine Research and Development Base Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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Abstract

The invention belongs to cosmetic technical fields, and in particular to a kind of Golden flower whitening and spot eliminating cream and preparation method thereof.The Golden flower whitening and spot eliminating cream includes: Hibiscus esculentus L. extract, pale flag extract, apple berry extract, butanediol, cetearyl alcohol alcohol ether -25, cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, Natrulon H-10, isononanoic acid ethylhexyl, dimethyl silicone polymer, PEG-4 olive oleate, cetostearyl alcohol, glycine betaine, xanthan gum, preservative, essence and water.Golden flower whitening and spot eliminating cream of the present invention easily absorbs, safe and non-stimulating, can effectively desalinate the color spots such as chloasma, freckle, and skin whitening, the improvement colour of skin is dark yellow, and skin is enabled to restore delicate smooth.

Description

A kind of Golden flower whitening and spot eliminating cream and preparation method thereof
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of Golden flower whitening and spot eliminating cream and preparation method thereof.
Background technique
Color spot refers to the skin surface spot different with ambient color.Color spot is the increase due to dermal melanin and is formed The common face of one kind is brown or the skin disease of melanin pigmentation, damage capacitive, including freckle, chloasma, blackspot, solarization Spot etc..Color spot often comes across forehead, the bridge of the nose, cheek etc., also appears in neck, neck the back of the hand etc. once in a while.Sense of loving to make up and wearing beautiful clothes people is all There is it, although color spot is not unhealthful, many women are freckle on the face, chloasma and worry.The method of nti-freckle has very More, such as laser nti-freckle, dietotherapy nti-freckle, the freckle effect of laser nti-freckle is obvious, but there are security risk, and treatment cost compared with It is high;Dietotherapy nti-freckle by it is edible can toxin expelling whitening food or Chinese medicine to improve body, achieve the purpose that nti-freckle, but dietotherapy is dispelled Spot needs are adhered to for a long time, and effect is unobvious.Therefore, more persons select using cosmetics, and cosmetics are main at present There are nti-freckle creams, nti-freckle Essence, freckle dispelling powder and freckle-removing mask.
Golden flower (scientific name: Hibiseu Smanihot L.) also known as vegetable Furong, also referred to as wild lotus are annual herb brocades Kurrajong gumbo platymiscium.Flower of JINHUAKUI dietotherapeutic, Compendium of Material Medica record the medical value of sunset abelmoschus root, can heat-clearing, cool blood, solution Poison, spends nontoxic, has the effect of eliminating dampness and heat, anti-inflammatory analgesic.Modern medicine study shows that the general flavone of Golden flower has town Bitterly, anti-cerebral ischemia and treatment canker sore the effects of, contained complete protein, high glycan glue, dietary fiber, microelement Selenium, zinc, a variety of unsaponifiable matter etc. have significant adjusting human endocrine, immunity, increase human body drag, improve cardiovascular and cerebrovascular And microcirculation function, enhance antioxidant ability of organism, anti-inflammatory, town pain, the function such as antifatigue, anti-aging, anticancer, anti-cancer, reducing blood lipid Effect.Golden flower have good health-care efficacy, so at present Golden flower mainly as health care product use, as golden flower sunflower health tea, Golden flower mallow health care oral liquid, capsule etc..
But Golden flower is used in terms of edible and medicinal merely at present, greatly limit its use value.Golden flower Middle active constituent is numerous, can be applied in cosmetics.As Chinese patent application CN 105168038A discloses a kind of flower of JINHUAKUI Piece clay mask has and maintains containing Golden flower flower, sponge gourd flower, propylene glycol, carbomer, triethanolamine, citral etc. The effect of elasticity of skin, anti-oxidant and whitening, but it uses Golden flower flower, sponge gourd flower as functional raw material, golden flower Effective component in certain herbaceous plants with big flowers cannot the effect of sufficiently releasing, skin effect is bad.It is retrieved, rarely has Hibiscus esculentus L. extract in whitening spot-removing Application in class cosmetics.
To sum up, it is necessary to research and develop a kind of Golden flower whitening and spot eliminating cream, on the one hand enrich the application field of Golden flower and its make With value, on the other hand also meet the needs of people, for people provide it is a kind of newly, effective whitening and spot eliminating cream.
Summary of the invention
For overcome the deficiencies in the prior art, the purpose of the present invention is to provide a kind of Golden flower whitening and spot eliminating cream, temperature And pro-skin, it easily absorbs, safe and non-stimulating, freckle removing and whitening effect is good.
To achieve the goals above, technical scheme is as follows:
A kind of Golden flower whitening and spot eliminating cream is grouped as by the group of following weight percent meter: Hibiscus esculentus L. extract 2.0~ 4.0%, pale flag extract 0.5~1.5%, apple berry extract 0.3~1.0%, butanediol 4~8%, cetostearyl alcohol Ether -251~2%, cetearyl alcohol alcohol ether -61~2%, ethylhexyl palmitate 2~5%, caprylic/capric triglyceride 2~ 5%, Natrulon H-10 2~5%, isononanoic acid ethylhexyl 1~3%, dimethyl silicone polymer 2~3%, PEG-4 olive oleate 1~2%, cetostearyl alcohol 0.5~2%, glycine betaine 0.2~1%, xanthan gum 0.2~0.6%, preservative 0.1~0.4%, perfume Essence 0.01~0.05%, surplus is water.
As a preferred embodiment of the present invention, the Golden flower whitening and spot eliminating cream by following weight percent meter component Composition: Hibiscus esculentus L. extract 3.0%, pale flag extract 1.0%, apple berry extract 0.6%, butanediol 6%, spermaceti are hard Lipidol ether -251%, cetearyl alcohol alcohol ether -62%, ethylhexyl palmitate 3%, caprylic/capric triglyceride 4%, polyglycereol - 104%, isononanoic acid ethylhexyl 2%, dimethyl silicone polymer 2.5%, PEG-4 olive oleate 1.5%, cetostearyl alcohol 1.5%, glycine betaine 0.8%, xanthan gum 0.5%, preservative 0.2%, essence 0.05%, surplus are water.
Further, the Hibiscus esculentus L. extract is made by following methods: taking dry Golden flower flower, its weight is added The water of 4~6 times of amounts, heating and refluxing extraction 2~3 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, Obtain concentrate, as Hibiscus esculentus L. extract.
Further, the preservative is one or both of methyl hydroxybenzoate and Nipasol.
Correspondingly, the present invention also provides the methods of above-mentioned Golden flower whitening and spot eliminating cream, specifically includes the following steps:
The preparation of S1, Hibiscus esculentus L. extract: taking dry Golden flower flower, and the water of 4~6 times of its weight amounts, heating is added Refluxing extraction 2~3 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, as golden Tree mallow extract, it is spare;
S2, by cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, dimethyl silicone polymer, Cetostearyl alcohol, cetearyl alcohol alcohol ether -25, isononanoic acid ethylhexyl and PEG-4 olive oleate are placed in oily phase pot, are heated to It 80~85 DEG C, stirs to being completely dissolved, obtains material A, keep the temperature spare;
S3, Jiang Shui, butanediol, Natrulon H-10, xanthan gum and glycine betaine are added in water phase pot, are heated to 80~85 DEG C, stir It mixes to after being completely dissolved and is pumped into warmed-up emulsifying pot, open stirring, then material A is slowly pumped into emulsion pot, Cool down after 5~10min of matter;
S4, continue to be cooled to 45 DEG C, be added Hibiscus esculentus L. extract, pale flag extract, apple berry extract, essence and Preservative is stirred until homogeneous, sampling Detection, discharges after qualified and Golden flower whitening and spot eliminating cream is made.
In the inventive solutions, Golden flower water extract obtained is extracted using under certain condition as main function Ingredient has certain nti-freckle and whitening effect, but effect is not fully up to expectations;So inventor is by continuous research and examination It tests, Golden flower water extract is compounded with existing pale flag extract, apple berry extract by a certain percentage, find Its nti-freckle and whitening effect are greatly improved, and have exceeded the foresighted technical effect range of inventor institute;Three kinds of plants are living Property ingredient is in conjunction with the matrix auxiliary material such as cetostearyl alcohol, glycine betaine, glycerol, ethylhexyl palmitate, so that Golden flower of the present invention Whitening and spot eliminating cream is easy to be absorbed by the skin, and does not clearly stick greasy after use, can be used for a long time.
Therefore, compared with prior art, present invention has an advantage that
(1) Golden flower whitening and spot eliminating cream of the present invention contains Hibiscus esculentus L. extract, pale flag extract, apple berry extract Etc. active components of plants abundant, the color spots such as chloasma, freckle can be desalinated quickly by percutaneous absorption, skin whitening improves black The dim mute skin of plain calmness bring enables skin restore delicate smooth.
(2) Golden flower whitening and spot eliminating cream each component collaboration of the present invention, freckle removing and whitening effect is good, and safe and non-stimulating, system Stablize, while the preparation method of Golden flower whitening and spot eliminating cream of the present invention is simple, and process stabilizing is convenient to carry out, can industrialized production, Be conducive to promote and apply.
Specific embodiment
The present invention is further described below by way of specific embodiment, but the present invention is not limited only to following embodiment.? It in the scope of the present invention or is not departing from the contents of the present invention, in spirit and scope, the present invention is suitably modified, is replaced The identical component of effect, it will become apparent to those skilled in the art that they are considered as including of the invention Within the scope of.
Pale flag extract described in the embodiment of the present invention is purchased from Li Meida Fine Chemical Co., Ltd, article No. ZJF- 01200429。
The apple berry extract is purchased from Guangzhou Ming Hui Fine Chemical Co., Ltd, article No. PW1331PG0244.
Embodiment 1, Golden flower whitening and spot eliminating cream of the present invention and its preparation
Formula: Hibiscus esculentus L. extract 3.0kg, pale flag extract 1.0kg, apple berry extract 0.6kg, butanediol 6kg, cetearyl alcohol alcohol ether -251kg, cetearyl alcohol alcohol ether -62kg, ethylhexyl palmitate 3kg, caprylic/capric triglyceride 4kg, Natrulon H-10 4kg, isononanoic acid ethylhexyl 2kg, dimethyl silicone polymer 2.5kg, PEG-4 olive oleate 1.5kg, Cetostearyl alcohol 1.5kg, glycine betaine 0.8kg, xanthan gum 0.5kg, methyl hydroxybenzoate 0.1kg, Nipasol 0.1kg, essence 0.05kg, deionized water supply 100kg.
The Hibiscus esculentus L. extract is made by following methods: taking dry Golden flower flower, 5 times of its weight amounts are added Water, heating and refluxing extraction 2 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, i.e., For Hibiscus esculentus L. extract.
Preparation method:
The preparation of S1, Hibiscus esculentus L. extract: taking dry Golden flower flower, and the water of 5 times of its weight amounts is added, is heated to reflux It extracts 2 hours, filtering, filtrate is concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, and as Golden flower mentions Object is taken, it is spare;
S2, by cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, dimethyl silicone polymer, Cetostearyl alcohol, cetearyl alcohol alcohol ether -25, isononanoic acid ethylhexyl and PEG-4 olive oleate are placed in oily phase pot, are heated to It 80 DEG C, stirs to being completely dissolved, obtains material A, keep the temperature spare;
S3, Jiang Shui, butanediol, Natrulon H-10, xanthan gum and glycine betaine are added in water phase pot, are heated to 80 DEG C, stirring is extremely It is pumped into after being completely dissolved in warmed-up emulsifying pot, opens stirring, then material A is slowly pumped into emulsion pot, homogeneous Cool down after 10min;
S4, continue to be cooled to 45 DEG C, be added Hibiscus esculentus L. extract, pale flag extract, apple berry extract, essence, Methyl hydroxybenzoate and Nipasol are stirred until homogeneous, sampling Detection, discharge after qualified and Golden flower whitening and spot eliminating cream is made.
Embodiment 2, Golden flower whitening and spot eliminating cream of the present invention and its preparation
Formula: Hibiscus esculentus L. extract 2.0kg, pale flag extract 0.5kg, apple berry extract 0.3kg, butanediol 4kg, cetearyl alcohol alcohol ether -251kg, cetearyl alcohol alcohol ether -61kg, ethylhexyl palmitate 2kg, caprylic/capric triglyceride 5kg, Natrulon H-10 5kg, isononanoic acid ethylhexyl 1kg, dimethyl silicone polymer 3kg, PEG-4 olive oleate 1kg, spermaceti Stearyl alcohol 2kg, glycine betaine 0.2kg, xanthan gum 0.2kg, methyl hydroxybenzoate 0.05kg, Nipasol 0.05kg, essence 0.01kg, go Ionized water supplies 100kg.
The Hibiscus esculentus L. extract is made by following methods: taking dry Golden flower flower, 4 times of its weight amounts are added Water, heating and refluxing extraction 2 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, i.e., For Hibiscus esculentus L. extract.
Preparation method:
The preparation of S1, Hibiscus esculentus L. extract: taking dry Golden flower flower, and the water of 4 times of its weight amounts is added, is heated to reflux It extracts 2 hours, filtering, filtrate is concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, and as Golden flower mentions Object is taken, it is spare;
S2, by cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, dimethyl silicone polymer, Cetostearyl alcohol, cetearyl alcohol alcohol ether -25, isononanoic acid ethylhexyl and PEG-4 olive oleate are placed in oily phase pot, are heated to It 85 DEG C, stirs to being completely dissolved, obtains material A, keep the temperature spare;
S3, Jiang Shui, butanediol, Natrulon H-10, xanthan gum and glycine betaine are added in water phase pot, are heated to 85 DEG C, stirring is extremely It is pumped into after being completely dissolved in warmed-up emulsifying pot, opens stirring, then material A is slowly pumped into emulsion pot, homogeneous Cool down after 5min;
S4, continue to be cooled to 45 DEG C, be added Hibiscus esculentus L. extract, pale flag extract, apple berry extract, essence, Methyl hydroxybenzoate and Nipasol are stirred until homogeneous, sampling Detection, discharge after qualified and Golden flower whitening and spot eliminating cream is made.
Embodiment 3, Golden flower whitening and spot eliminating cream of the present invention and its preparation
Formula: Hibiscus esculentus L. extract 4.0kg, pale flag extract 1.5kg, apple berry extract 1.0kg, butanediol 8kg, cetearyl alcohol alcohol ether -252kg, cetearyl alcohol alcohol ether -62kg, ethylhexyl palmitate 5kg, caprylic/capric triglyceride 2kg, Natrulon H-10 2kg, isononanoic acid ethylhexyl 3kg, dimethyl silicone polymer 2kg, PEG-4 olive oleate 2kg, spermaceti Stearyl alcohol 0.5kg, glycine betaine 1kg, xanthan gum 0.6kg, methyl hydroxybenzoate 0.3kg, Nipasol 0.1kg, essence 0.05kg, go from Sub- water supplies 100kg.
The Hibiscus esculentus L. extract is made by following methods: taking dry Golden flower flower, 6 times of its weight amounts are added Water, heating and refluxing extraction 3 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, i.e., For Hibiscus esculentus L. extract.
Preparation method:
The preparation of S1, Hibiscus esculentus L. extract: taking dry Golden flower flower, and the water of 6 times of its weight amounts is added, is heated to reflux It extracts 3 hours, filtering, filtrate is concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, and as Golden flower mentions Object is taken, it is spare;
S2, by cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, dimethyl silicone polymer, Cetostearyl alcohol, cetearyl alcohol alcohol ether -25, isononanoic acid ethylhexyl and PEG-4 olive oleate are placed in oily phase pot, are heated to It 80 DEG C, stirs to being completely dissolved, obtains material A, keep the temperature spare;
S3, Jiang Shui, butanediol, Natrulon H-10, xanthan gum and glycine betaine are added in water phase pot, are heated to 80 DEG C, stirring is extremely It is pumped into after being completely dissolved in warmed-up emulsifying pot, opens stirring, then material A is slowly pumped into emulsion pot, homogeneous Cool down after 8min;
S4, continue to be cooled to 45 DEG C, be added Hibiscus esculentus L. extract, pale flag extract, apple berry extract, essence, Methyl hydroxybenzoate and Nipasol are stirred until homogeneous, sampling Detection, discharge after qualified and Golden flower whitening and spot eliminating cream is made.
Comparative example 1,
Formula: Hibiscus esculentus L. extract 4.6kg, butanediol 6kg, cetearyl alcohol alcohol ether -251kg, cetearyl alcohol alcohol ether - 62kg, ethylhexyl palmitate 3kg, caprylic/capric triglyceride 4kg, Natrulon H-10 4kg, isononanoic acid ethylhexyl 2kg, gather Dimethyl siloxane 2.5kg, PEG-4 olive oleate 1kg, cetostearyl alcohol 1.5kg, glycine betaine 0.8kg, xanthan gum 0.5kg, Methyl hydroxybenzoate 0.2kg, essence 0.05kg, deionized water supply 100kg.
The preparation of Hibiscus esculentus L. extract and the preparation method reference implementation example 1 of creams.
Compared with Example 1, the difference of this comparative example is: being free of pale flag extract and apple berry extract.
Comparative example 2,
Formula: Hibiscus esculentus L. extract 3.45kg, pale flag extract 1.15kg, butanediol 6kg, cetearyl alcohol alcohol ether- 251kg, cetearyl alcohol alcohol ether -62kg, ethylhexyl palmitate 3kg, caprylic/capric triglyceride 4kg, Natrulon H-10 4kg, Isononanoic acid ethylhexyl 2kg, dimethyl silicone polymer 2.5kg, PEG-4 olive oleate 1kg, cetostearyl alcohol 1.5kg, beet Alkali 0.8kg, xanthan gum 0.5kg, methyl hydroxybenzoate 0.2kg, essence 0.05kg, deionized water supply 100kg.
The preparation of Hibiscus esculentus L. extract and the preparation method reference implementation example 1 of creams.
Compared with Example 1, the difference of this comparative example is: being free of apple berry extract.
Comparative example 3,
Formula: pale flag extract 2.9kg, apple berry extract 1.7kg, butanediol 6kg, cetearyl alcohol alcohol ether- 251kg, cetearyl alcohol alcohol ether -62kg, ethylhexyl palmitate 3kg, caprylic/capric triglyceride 4kg, Natrulon H-10 4kg, Isononanoic acid ethylhexyl 2kg, dimethyl silicone polymer 2.5kg, PEG-4 olive oleate 1kg, cetostearyl alcohol 1.5kg, beet Alkali 0.8kg, xanthan gum 0.5kg, methyl hydroxybenzoate 0.2kg, essence 0.05kg, deionized water supply 100kg.
Preparation method reference implementation example 1.
Compared with Example 1, the difference of this comparative example is: being free of Hibiscus esculentus L. extract.
Test example one, product index evaluation
Golden flower whitening and spot eliminating cream made from Examples 1 to 3 is tested, as a result as follows:
One, stability test:
1, heat-resistant stability investigates (45 DEG C × for 24 hours): qualified;
2, it resists cold study on the stability (- 15 DEG C × for 24 hours): qualified.
Two, hygienic requirements: meet the relevant regulations of " cosmetics health specification " (version in 2007).
Three, human safety is tested: passing through " cosmetics health specification " (version in 2007) human skin patch.
Test example two, product effect assessment
First part:
One, trial target: whitening and spot eliminating cream made from Examples 1 to 3 and comparative example 1~3
Two, tested crowd
Gender number: selection face has different degrees of chloasma and dark yellow Ms 240 of skin
Age: between 30~55 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping: it is divided into 6 groups, every group 40.
Three, test method:
Each group subject tries out above-mentioned whitening and spot eliminating cream respectively, sooner or later respectively using primary, continuous use 8 weeks.
Evaluation criterion: 1. effective: naked eyes 50% or more chloasma fading of view, skin is more glossy, the colour of skin is dark yellow have it is brighter It is aobvious to improve;2. improving: naked eyes 10% or more chloasma fading of view or chloasma color turn light, and skin is glossy, and the colour of skin is dark yellow to be had Improved;3. invalid: naked eyes before and after use depending on not changing.Obvious effective rate=effective number of cases/total number of cases × 100%;Total effective rate =(effective number of cases+improvement number of cases)/total number of cases × 100%.
Four, evaluation result such as the following table 1:
The evaluation result table of each whitening and spot eliminating cream of table 1
From upper table 1:
(1) freckle effect of 1~3 Golden flower whitening and spot eliminating cream of the embodiment of the present invention is significant, and can be obviously improved the colour of skin It is dark yellow, it enables whitening skin glossy, reaches 97% or more using total effective rate after whitening and spot eliminating cream of the present invention 8 weeks, obvious effective rate reaches To 70% or more.The wherein obvious effective rate and total effective rate highest of 1 Golden flower whitening and spot eliminating cream of embodiment, using effect is best, is Highly preferred embodiment of the present invention.Subject does not occur the undesirable conditions such as skin allergy, red and swollen phenomenon during on probation simultaneously.
(2) compared with Example 1, the only Hibiscus esculentus L. extract of comparative example 1, to chloasma, the colour of skin is dark yellow certain effect Fruit but undesirable;Comparative example 2 is free of apple berry extract, and whitening spot-removing effect is poorer than the embodiment of the present invention;Comparative example 3 is not Containing Hibiscus esculentus L. extract, it is ideal to improve the dark yellow whitening effect of the colour of skin, but freckle effect is poor.
Second part:
One, trial target: whitening and spot eliminating cream made from Examples 1 to 3 and comparative example 1~3
Two, tested crowd
Gender number: selection face has the Ms 240 of the color spots such as different degrees of chloasma, freckle, butterfly macules and senile plaque Example
Age: between 30~60 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Grouping: it is divided into 6 groups, every group 40.
Three, test method:
Each group subject tries out above-mentioned whitening and spot eliminating cream respectively, sooner or later respectively using primary, continuous use 4 weeks.
Four, test assessment result is as follows:
2 embodiment of table, 1 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
3 embodiment of table, 2 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
4 embodiment of table, 3 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
5 comparative example of table, 1 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
6 comparative example of table, 2 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
7 comparative example of table, 3 whitening and spot eliminating cream tries out (4 weeks) feedback conclusive tables
By upper table 2~7 it is found that the degree of recognition of Examples 1 to 3 whitening and spot eliminating cream is high, subject indicates to use the whitening After content in freckle cream, the color spots such as chloasma, freckle, butterfly macules and senile plaque on the face are significantly reduced, and freckle effect is fine, and the colour of skin is dark It is yellow, dry etc. be improved significantly, whitening effect is good, and is easy to absorb, salubrious using rear skin sense.Wherein subject is to implementation The whitening and spot eliminating cream of example 1 is especially approved.There are the bad shapes such as skin allergy, red and swollen phenomenon in non-someone in the questionnaire of subject simultaneously Condition.Comparative example 1~3 lacks certain components in whitening and spot eliminating cream of the present invention, and using effect is not so good as Examples 1 to 3.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe The personage for knowing this technology all without departing from the spirit and scope of the present invention, carries out modifications and changes to above-described embodiment.Cause This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as At all equivalent modifications or change, should be covered by the claims of the present invention.

Claims (4)

1. a kind of Golden flower whitening and spot eliminating cream, which is characterized in that be grouped as by the group of following weight percent meter: Golden flower is extracted Object 2.0~4.0%, pale flag extract 0.5~1.5%, apple berry extract 0.3~1.0%, butanediol 4~8%, whale Wax tristearin alcohol ether -251~2%, cetearyl alcohol alcohol ether -61~2%, ethylhexyl palmitate 2~5%, caprylic/capric glycerol three Ester 2~5%, Natrulon H-10 2~5%, isononanoic acid ethylhexyl 1~3%, dimethyl silicone polymer 2~3%, PEG-4 olive Oleate 1~2%, cetostearyl alcohol 0.5~2%, glycine betaine 0.2~1%, xanthan gum 0.2~0.6%, preservative 0.1~ 0.4%, essence 0.01~0.05%, surplus are water;
The Hibiscus esculentus L. extract the preparation method comprises the following steps: take dry Golden flower flower, the water of 4~6 times of its weight amounts are added, add Circumfluence distillation 2~3 hours, filtering, filtrate was concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, as Hibiscus esculentus L. extract.
2. Golden flower whitening and spot eliminating cream as described in claim 1, which is characterized in that be grouped by the group of following weight percent meter At: Hibiscus esculentus L. extract 3.0%, pale flag extract 1.0%, apple berry extract 0.6%, butanediol 6%, cetearyl alcohol Alcohol ether -251%, cetearyl alcohol alcohol ether -62%, ethylhexyl palmitate 3%, caprylic/capric triglyceride 4%, polyglycereol - 104%, isononanoic acid ethylhexyl 2%, dimethyl silicone polymer 2.5%, PEG-4 olive oleate 1.5%, cetostearyl alcohol 1.5%, glycine betaine 0.8%, xanthan gum 0.5%, preservative 0.2%, essence 0.05%, surplus are water.
3. Golden flower whitening and spot eliminating cream as claimed in claim 1 or 2, which is characterized in that the preservative is methyl hydroxybenzoate and hydroxyl One or both of phenylpropyl alcohol ester.
4. a kind of method for preparing Golden flower whitening and spot eliminating cream as claimed in claim 1 or 2, which is characterized in that including following step It is rapid:
The preparation of S1, Hibiscus esculentus L. extract: taking dry Golden flower flower, and the water of 4~6 times of its weight amounts is added, is heated to reflux It extracts 2~3 hours, filtering, filtrate is concentrated into the 1/3 of former filtrate volume under vacuum decompression, obtains concentrate, as Golden flower Extract, it is spare;
S2, by cetearyl alcohol alcohol ether -6, ethylhexyl palmitate, caprylic/capric triglyceride, dimethyl silicone polymer, spermaceti Stearyl alcohol, cetearyl alcohol alcohol ether -25, isononanoic acid ethylhexyl and PEG-4 olive oleate are placed in oily phase pot, it is heated to 80~ It 85 DEG C, stirs to being completely dissolved, obtains material A, keep the temperature spare;
S3, Jiang Shui, butanediol, Natrulon H-10, xanthan gum and glycine betaine are added in water phase pot, are heated to 80~85 DEG C, stirring is extremely It is pumped into after being completely dissolved in warmed-up emulsifying pot, opens stirring, then material A is slowly pumped into emulsion pot, homogeneous 5~ Cool down after 10min;
S4, continue to be cooled to 45 DEG C, Hibiscus esculentus L. extract, pale flag extract, apple berry extract, essence and anti-corrosion is added Agent is stirred until homogeneous, sampling Detection, discharges after qualified and Golden flower whitening and spot eliminating cream is made.
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CN106580797B (en) * 2016-12-30 2019-03-05 广州科盈化妆品有限公司 A kind of whitening and spot eliminating cream and preparation method thereof
CN107362108A (en) * 2017-09-26 2017-11-21 深圳聚源宝鼎农业生物科技产业发展有限公司 A kind of Golden flower facial mask and preparation method thereof
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