CN106042548A - High-barrier composite-layer medical infusion bag - Google Patents
High-barrier composite-layer medical infusion bag Download PDFInfo
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- CN106042548A CN106042548A CN201610317554.3A CN201610317554A CN106042548A CN 106042548 A CN106042548 A CN 106042548A CN 201610317554 A CN201610317554 A CN 201610317554A CN 106042548 A CN106042548 A CN 106042548A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2250/00—Layers arrangement
- B32B2250/24—All layers being polymeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/40—Properties of the layers or laminate having particular optical properties
- B32B2307/412—Transparent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/724—Permeability to gases, adsorption
- B32B2307/7242—Non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a high-barrier composite-layer medical infusion bag. The high-barrier composite-layer medical infusion bag comprises an infusion bag body, wherein the infusion bag body comprises an inner bag layer, a middle bag layer and an outer bag layer, the middle bag layer is compatible with the outer bag layer and the inner bag layer, and thus, the outer bag layer and the inner bag layer are adhered together; and a transition layer is formed on the internal wall of the inner bag layer of the infusion bag by adopting low-temperature magnetron sputtering, the internal wall of the transition layer is plated with a barrier layer, the external wall of the outer bag layer is also plated with a barrier layer, and a sterilizing layer is formed on the external wall of the barrier layer of the outer bag layer by adopting low-temperature magnetron sputtering. According to the high-barrier composite-layer medical infusion bag, macromolecular-film additives are prevented from being migrated into drugs, and outer plated layers are high in barrier, have multiple functions such as transparent and ultraviolet absorbing, i.e., shading functions and are used for improving sterilizing effects of the sterilizing layer and meanwhile carrying out secondary protection and barrier actions.
Description
Technical field
The present invention relates to the production technical field of a kind of transfusion bag, particularly relate to a kind of high-barrier composite bed medical infusion
Bag.
Background technology
At present, Medical transfusion container has plastic bottle, co-extrusion infusion film and blended transfusion bag several types.The most simply it is situated between
The content of these several infusion vessels of continuing and its weak point:
The plastic bottle announced such as patent No. CN 201759852U is lightweight, has the fine compatibility with medicinal liquid, but in transfusion
Mode aspect still has the defect of vial, needs air inlet, thus results in harmful antibacterial and the possibility of microgranule increase in bottle,
Therefore the development of plastic bottle is restricted.
The co-extrusion infusion film that and for example patent No. CN 101462389A announces, is the film of three layers, has good temperature tolerance,
Excellent clarity, broad heat-sealing temperature scope, the pliability of high and low temperature environment, the good compatibility, but internal layer is poly-
Propylene, outer layer does not has barrier layer, is to use coextrusion process, and expensive, production cost is high, and leakage is its fault of construction.
The blend composition transfusion bag that and for example patent No. CN 102397160A announces, this transfusion bag bag has lightweight, cost
Low, quality is high, the feature of integrated molding, in use without air inlet, use atmospheric pressure transfusion, but transfusion flexible bag be only
Have the bag of the blend composition of a layer or two-layer, material transport relevant with medicinal liquid contact layer to medicinal liquid, its safety and barrier
Need to be considered.
The patent of invention of one Patent No. CN 101411672B of the applicant, discloses a kind of medical infusion soft bag
And manufacture method and method for shaping, the polypropylene combination cover of transfusion bag mouth cooperation outsourcing, fusing point is incomplete with bag material
Unanimously, take and check its sealing by fusing effect quarter；Added with toughened plastics in transfusion bag raw material, expensive, safety is the lowest；Transfusion bag
Certainly performance is emptied for what the ratio of flat and width and thickness directly affected medicinal liquid more than or equal to 3；Transfusion bag side is smooth
Curved surface circular arc, is unfavorable for the emptying certainly of medicinal liquid；Transfusion bag body is flexible plastic, and transfusion bag body be placed on the mould of respective shapes
Tool inner chamber obtains sizing；Draw-ring type polypropylene combination cover, it may appear that draw ring is easily broken, be difficult to pull open, water vapour at draw ring during sterilizing
Easily penetrate into, pollute；The one-step method (note stretch blow, just for bag, do not include composite cover) of its production technology or two steps simultaneously
Method (injection, bag) is the most complex and easy infection foreign body.The invention of another patent No. CN103519991A of the applicant
Patent, discloses a kind of Novel plastic infusion bag and manufacture method thereof, be a kind of simple in construction, low cost of manufacture, can allow defeated
Liquid bag transfusion time need not add air inlet needle, when infuse with non-air admission type transfusion needle, completely can oneself empty and will not blood back, bag
Shape there will not be more serious deformation and the transfusion bag that can stably stand；But this transfusion bag is one layer, it becomes segregation third
Alkene has related substance can move to medicinal liquid, its safety, and barrier needs to be considered.
The patent of invention of one patent No. CN 1415644A of the applicant, discloses a kind of anionic polymerization nylon and receives
Nano composite material, its intensity is high, and good rigidly, barrier property is superior, dimensionally stable, and technique is simple, efficiency is high；According to before
The shortcoming of several infusion vessels introduced, the material that present invention employs above-mentioned patent carries out bag, is thus reaches high-barrier
Property, especially a kind of nano composite material of anionic polymerization nylon, it acts primarily as iris action.
The patent of invention of one patent No. CN103893012A of the applicant, discloses a kind of three layers of medical infusion bags,
After it just can make medicinal liquid flow out, the volume of bag diminishes, thus pressure becomes big, is so conducive to from emptying, and infusion process is without entering
Gas medicinal liquid can relatively constant speed gravity flow emptying, security performance is good, good barrier property, transfusion performance good, it is more convenient to use, and is used in doctor
In infusing, and the transfusion bag manufacturing approach craft of the present invention is advanced, once-forming, is suitable for the production of this transfusion bag.
Existing disclosed patent, its technical characteristic is the soft bag that PP TYPE is made, additional silicon dioxide plated film bag, adopts
Obtaining shortcoming with this plated film bag is that technics comparing is complicated, and production cost is higher.
And existing transfusion bag is through 121 degree of sterilizings, but in transport, using, outer layer has bacterium, therefore in sterilizing room not
Can use.
Summary of the invention
For the deficiencies in the prior art, the technical problem to be solved is to provide a kind of high-barrier composite bed doctor
By transfusion bag and manufacture method thereof, it is possible to improve the barrier property of material further.
In order to realize above-mentioned technical purpose, the present invention adopts the following technical scheme that: a kind of high-barrier composite bed medical infusion
Bag, including transfusion bag body, described transfusion bag body includes interior bag layer, middle bag layer and outer bag layer, described middle bag layer and outer bag layer, inner bag
Layer is compatible, thus is bonded together with interior bag layer by outer bag layer, and described interior bag layer is polythene material, middle bag layer be polypropylene,
Styrene-ethylene/butylene-styrene block copolymer and dopamine intermingling material, outer bag layer is polypropylene, Carboxylation benzene second
Alkene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material, described transfusion
The interior bag layer inwall of bag uses low temperature magnetic sputtering to form transition zone, and the inwall plating of described transition zone is provided with barrier layer, described outside
The outer wall of bag layer also plates and is provided with barrier layer, and the outer wall of the barrier layer of described outer bag layer uses low temperature magnetic sputtering to form stenlizing layer.
Further, the silicon dioxide of the material of described barrier layer, the material of described stenlizing layer and transition zone is all nanometer
Titanium dioxide.
Further, described stenlizing layer is the blended layer material of nano titanium oxide and polyurethanes.
Further, the dopamine percentage by weight of described middle bag layer is 5-95%.
Further, described nano silicon percentage by weight is 75-85%.
The manufacture method of a kind of high-barrier composite bed medical infusion bags, comprises the following steps:
1): embedding by making the polythene material of interior bag layer, the polypropylene of middle bag layer, styrene-ethylene/butylene-styrene
Section copolymer and dopamine intermingling material and the polypropylene of outer bag layer, carboxylated styrene-ethylene/butylene-styrene block are common
The material of polymers and nano composite material of anionic polymerization nylon blended layer is purified respectively and prepares by formula, afterwards
Stir mixing respectively；
2): preheat injection mold, the material of three bag layers step one preparation mixed adds heat fusing respectively,
Temperature is 250～280 DEG C, and the thick liquid material of three bag layer materials after melting is injected in mould by three die heads respectively
It is molded into interior bag layer, middle bag layer and the bag embryo of outer bag layer, and the bag embryo of three layers be previously formed is placed cooling molding；
3): the interior bag layer bag embryo inwall cooling down molding to step 2 uses low temperature magnetic sputtering to form nano titanium oxide mistake
Cross layer, then plate to the inwall of transition zone and set silica barrier layer；
4): the outer bag layer outer wall plating cooling down molding to step 2 sets silica barrier layer, backward silica barrier layer
Outer wall uses low temperature magnetic sputtering to form nano titanium oxide outer wall stenlizing layer；
5): the bag embryo of step 3 and 4 three layers formed is sent in air feeder and carries out blowing bag, air blowing air pressure be 1.5～
1.8MPa, blow molding, make the transfusion bag of required three layer；
6): by the transfusion bag liquid drug of three layers that step 4 prepares；
7): transfusion bag complete for liquid drug is sealed.
The technical characterstic of the present invention and effect be: the present invention uses the nanometer titanium dioxide layer formed by low temperature magnetic sputtering
There is antibacterial functions, and the stenlizing layer generated also have transparent, to absorb ultraviolet i.e. lucifuge function etc. multi-functional, improves medicine
Safety；
In the present invention, the dopamine of bag layer has elimination through oxygen, bonding, barriers function, improves the resistance of material further
Separating performance；
The interior bag layer inwall of the present invention uses first sputtering nanometer titanium dioxide ti interlayer, afterwards plating nanometer titanium dioxide silicon cladding,
The additive stoping polymeric membrane moves in medicine, serving high barrier.Therefore this product has glass high safety
Property, the advantage of high barrier, it may have soft bag from emptying advantage.I.e. there is the two advantage, the shortcoming overcoming the two, simultaneously
Outer bag layer uses first plating nanometer titanium dioxide silicon cladding, rear sputtering nanometer titanium dioxide ti interlayer, therefore has transparent, absorption ultraviolet
Line i.e. lucifuge functions etc. are multi-functional, and are used for improving the bactericidal effect of stenlizing layer, are also carried out the effect that second protection intercepts simultaneously.
Accompanying drawing explanation
Fig. 1 is the cross-sectional view of the present invention；
Fig. 2 is the Facad structure schematic diagram of the present invention.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, right
The present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, and
It is not used in the restriction present invention.
Embodiment 1
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, thus are bonded together with interior bag layer 2 by outer bag layer 4, inner bag
Layer 2 is polythene material, middle bag layer 3 being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixing material, and the percentage by weight of dopamine is 5%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blended layer material, interior bag layer 2 inwall of transfusion bag uses low
Temperature magnetron sputtering forms transition zone 5, and the inwall plating of transition zone 5 is provided with barrier layer 6, and the outer wall of outer bag layer 4 also plates and is provided with barrier layer
6, the outer wall employing low temperature magnetic sputtering formation stenlizing layer 7 of the barrier layer 6 of outer bag layer 4, the silicon dioxide of the material of barrier layer 6,
The material of stenlizing layer 7 and transition zone 5 is all nano titanium oxide.
And the process of the said goods comprises the following steps:
First, it is polypropylene, styrene-ethylene/butylene-benzene second by making the polythene material of interior bag layer 2, middle bag layer 3
Alkene block copolymer and the intermingling material of dopamine, and the percentage by weight of dopamine is 5% and the polypropylene of outer bag layer 4, carboxylic
Acidifying styrene-ethylene/butylene-styrene block copolymer and the material of nano composite material of anionic polymerization nylon blended layer
It is purified respectively and prepares by formula, stirring mixing the most respectively；
Secondly, preheating injection mold, the material of three bag layers step one preparation mixed adds hot melt respectively
Melting, temperature is 250～280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
Tool is molded into interior bag layer 2, middle bag layer 3 and the bag embryo of outer bag layer 4, and the bag embryo placement of be previously formed three layers is cooled to
Type；
Again, 2 bags of embryo inwalls employing low temperature magnetic sputterings formation nano titanium oxides of interior bag layer of molding are cooled down to step 2
Transition zone 5, then plates to the inwall of transition zone 5 and sets silica barrier layer 6；
Again, the outer bag layer 4 outer wall plating cooling down molding to step 2 sets silica barrier layer 6, and backward silicon dioxide intercepts
The outer wall of layer 6 uses low temperature magnetic sputtering to form nano titanium oxide outer wall stenlizing layer 7；
Again, the bag embryo of step 3 and 4 three layers formed is sent in air feeder and carries out blowing bag, air blowing air pressure be 1.5～
1.8MPa, blow molding, make the transfusion bag of required three layer；
Again, the transfusion bag liquid drug of three layers step 4 prepared；
Finally, transfusion bag complete for liquid drug is sealed.
Embodiment 2
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, thus are bonded together with interior bag layer 2 by outer bag layer 4, inner bag
Layer 2 is polythene material, middle bag layer 3 being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixing material, and the percentage by weight of dopamine is 95%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blended layer material, interior bag layer 2 inwall of transfusion bag uses low
Temperature magnetron sputtering forms transition zone 5, and the inwall plating of transition zone 5 is provided with barrier layer 6, and the outer wall of outer bag layer 4 also plates and is provided with barrier layer
6, the outer wall employing low temperature magnetic sputtering formation stenlizing layer 7 of the barrier layer 6 of outer bag layer 4, the silicon dioxide of the material of barrier layer 6,
Stenlizing layer is the blended layer material of nano titanium oxide and polyurethanes, and nano silicon percentage by weight is 75-
85%.
And the process of the said goods comprises the following steps:
First, it is polypropylene, styrene-ethylene/butylene-benzene second by making the polythene material of interior bag layer 2, middle bag layer 3
Alkene block copolymer and the intermingling material of dopamine, and the percentage by weight of dopamine is 95% and the polypropylene of outer bag layer 4, carboxylic
Acidifying styrene-ethylene/butylene-styrene block copolymer and the material of nano composite material of anionic polymerization nylon blended layer
It is purified respectively and prepares by formula, stirring mixing the most respectively；
Secondly, preheating injection mold, the material of three bag layers step one preparation mixed adds hot melt respectively
Melting, temperature is 250～280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
Tool is molded into interior bag layer 2, middle bag layer 3 and the bag embryo of outer bag layer 4, and the bag embryo placement of be previously formed three layers is cooled to
Type；
Again, 2 bags of embryo inwalls employing low temperature magnetic sputterings formation nano titanium oxides of interior bag layer of molding are cooled down to step 2
Transition zone 5, then plates to the inwall of transition zone 5 and sets silica barrier layer 6；
Again, the outer bag layer 4 outer wall plating cooling down molding to step 2 sets silica barrier layer 6, and backward silicon dioxide intercepts
The outer wall of layer 6 uses low temperature magnetic sputtering to form the blended layer material walls stenlizing layer 7 of nano titanium oxide and polyurethanes；
Again, the bag embryo of step 3 and 4 three layers formed is sent in air feeder and carries out blowing bag, air blowing air pressure be 1.5～
1.8MPa, blow molding, make the transfusion bag of required three layer；
Again, the transfusion bag liquid drug of three layers step 4 prepared；
Finally, transfusion bag complete for liquid drug is sealed.
Embodiment 3
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, thus are bonded together with interior bag layer 2 by outer bag layer 4, inner bag
Layer 2 is polythene material, middle bag layer 3 being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixing material, and the percentage by weight of dopamine is 55%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blended layer material, interior bag layer 2 inwall of transfusion bag uses low
Temperature magnetron sputtering forms transition zone 5, and the inwall plating of transition zone 5 is provided with barrier layer 6, and the outer wall of outer bag layer 4 also plates and is provided with barrier layer
6, the outer wall employing low temperature magnetic sputtering formation stenlizing layer 7 of the barrier layer 6 of outer bag layer 4, the silicon dioxide of the material of barrier layer 6,
Stenlizing layer is the blended layer material of nano titanium oxide and polyurethanes, and nano silicon percentage by weight is 75-
85%.
And the process of the said goods comprises the following steps:
First, it is polypropylene, styrene-ethylene/butylene-benzene second by making the polythene material of interior bag layer 2, middle bag layer 3
Alkene block copolymer and the intermingling material of dopamine, and the percentage by weight of dopamine is 55% and the polypropylene of outer bag layer 4, carboxylic
Acidifying styrene-ethylene/butylene-styrene block copolymer and the material of nano composite material of anionic polymerization nylon blended layer
It is purified respectively and prepares by formula, stirring mixing the most respectively；
Secondly, preheating injection mold, the material of three bag layers step one preparation mixed adds hot melt respectively
Melting, temperature is 250～280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
Tool is molded into interior bag layer 2, middle bag layer 3 and the bag embryo of outer bag layer 4, and the bag embryo placement of be previously formed three layers is cooled to
Type；
Again, 2 bags of embryo inwalls employing low temperature magnetic sputterings formation nano titanium oxides of interior bag layer of molding are cooled down to step 2
Transition zone 5, then plates to the inwall of transition zone 5 and sets silica barrier layer 6；
Again, the outer bag layer 4 outer wall plating cooling down molding to step 2 sets silica barrier layer 6, and backward silicon dioxide intercepts
The outer wall of layer 6 uses low temperature magnetic sputtering to form the blended layer material walls stenlizing layer 7 of nano titanium oxide and polyurethanes；
Again, the bag embryo of step 3 and 4 three layers formed is sent in air feeder and carries out blowing bag, air blowing air pressure be 1.5～
1.8MPa, blow molding, make the transfusion bag of required three layer；
Again, the transfusion bag liquid drug of three layers step 4 prepared；
Finally, transfusion bag complete for liquid drug is sealed.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention
Any amendment, equivalent and the improvement etc. made within god and principle, should be included within the scope of the present invention.
Claims (6)
1. a high-barrier composite bed medical infusion bags, including transfusion bag body (1), described transfusion bag body (1) includes interior bag layer
(2), middle bag layer (3) and outer bag layer (4), described middle bag layer (3) and outer bag layer (4), interior bag layer (2) are compatible, thus by outer bag layer
(4) being bonded together with interior bag layer (2), described interior bag layer (2) is polythene material, middle bag layer (3) be polypropylene, styrene-
Ethylene/butylene-styrene block copolymer and the intermingling material of dopamine, outer bag layer (4) be polypropylene, carboxylated styrene-
Ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material, it is characterised in that:
Interior bag layer (2) inwall of described transfusion bag uses low temperature magnetic sputtering to form transition zone (5), the inwall plating of described transition zone (5)
Being provided with barrier layer (6), the outer wall of described outer bag layer (4) also plates and is provided with barrier layer (6), the barrier layer (6) of described outer bag layer (4)
Outer wall uses low temperature magnetic sputtering to form stenlizing layer (7).
High-barrier composite bed medical infusion bags the most according to claim 1, it is characterised in that: the material of described barrier layer (6)
The silicon dioxide of matter, the material of described stenlizing layer (7) and transition zone (5) is all nano titanium oxide.
High-barrier composite bed medical infusion bags the most according to claim 1, it is characterised in that: described middle bag layer (3) is many
Bar amine percentage by weight is 5-95%.
High-barrier composite bed medical infusion bags the most according to claim 1, it is characterised in that: described stenlizing layer is nanometer two
Titanium oxide and the blended layer material of polyurethanes.
High-barrier composite bed medical infusion bags the most according to claim 2, it is characterised in that: described nano silicon weight
Amount percentage ratio is 75-85%.
High-barrier composite bed medical infusion bags the most according to claim 1, it is characterised in that: comprise the following production steps that
1): the polythene material of interior bag layer (2), the polypropylene of middle bag layer (3), styrene-ethylene/butylene-styrene will be made
Block copolymer and dopamine intermingling material and the polypropylene of outer bag layer (4), carboxylated styrene-ethylene/butylene-styrene are embedding
The material of section copolymer and nano composite material of anionic polymerization nylon blended layer is purified respectively and prepares by formula,
Stir mixing the most respectively；
2) material of three the bag layers: preheat injection mold, step one preparation mixed adds heat fusing, temperature respectively
Being 250～280 DEG C, the thick liquid material of three bag layer materials after melting is injected in mould injection by three die heads respectively
Become interior bag layer (2), middle bag layer (3) and the bag embryo of outer bag layer (4), and the bag embryo of three layers be previously formed is placed cooling molding；
3): interior bag layer (2) the bag embryo inwall cooling down molding to step 2 uses low temperature magnetic sputtering to form nano titanium oxide transition
Layer (5), then plates to the inwall of transition zone (5) and sets silica barrier layer (6)；
4): outer bag layer (4) the outer wall plating cooling down molding to step 2 sets silica barrier layer (6), backward silica barrier layer
(6) outer wall uses low temperature magnetic sputtering to form nano titanium oxide outer wall stenlizing layer (7)；
5): carrying out blowing bag in the bag embryo of step 3 and 4 three layers formed is sent into air feeder, air blowing air pressure is 1.5～1.8MPa,
Blow molding, makes the transfusion bag of required three layer；
6): by the transfusion bag liquid drug of three layers that step 4 prepares；
7): transfusion bag complete for liquid drug is sealed.
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| CN201610317554.3A CN106042548B (en) | 2016-05-13 | 2016-05-13 | A kind of high-barrier composite bed medical infusion bags |
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| CN201610317554.3A CN106042548B (en) | 2016-05-13 | 2016-05-13 | A kind of high-barrier composite bed medical infusion bags |
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| CN106042548B CN106042548B (en) | 2018-06-19 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106667768A (en) * | 2016-12-30 | 2017-05-17 | 湖南金健药业有限责任公司 | Light-avoiding antibacterial infusion bag and preparation method thereof |
| CN110497671A (en) * | 2019-08-06 | 2019-11-26 | 安徽天润医用新材料有限公司 | A kind of high-barrier composite layer medical infusion bags and its production method |
| CN110743061A (en) * | 2019-10-10 | 2020-02-04 | 雷诺丽特朗活医药耗材（北京）有限公司 | Infusion bag and portable infusion bag |
| CN118024526A (en) * | 2024-04-15 | 2024-05-14 | 山东齐鲁乙烯化工股份有限公司 | Preparation method of sterilizing outer cover film of medicine bag |
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| CN110497671A (en) * | 2019-08-06 | 2019-11-26 | 安徽天润医用新材料有限公司 | A kind of high-barrier composite layer medical infusion bags and its production method |
| CN110497671B (en) * | 2019-08-06 | 2021-05-11 | 安徽天润医用新材料有限公司 | High-barrier composite layer medical infusion bag and production method thereof |
| CN110743061A (en) * | 2019-10-10 | 2020-02-04 | 雷诺丽特朗活医药耗材（北京）有限公司 | Infusion bag and portable infusion bag |
| CN118024526A (en) * | 2024-04-15 | 2024-05-14 | 山东齐鲁乙烯化工股份有限公司 | Preparation method of sterilizing outer cover film of medicine bag |
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