CN101485613A - Environment-friendly type infusion soft bag - Google Patents
Environment-friendly type infusion soft bag Download PDFInfo
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- CN101485613A CN101485613A CNA2009100041602A CN200910004160A CN101485613A CN 101485613 A CN101485613 A CN 101485613A CN A2009100041602 A CNA2009100041602 A CN A2009100041602A CN 200910004160 A CN200910004160 A CN 200910004160A CN 101485613 A CN101485613 A CN 101485613A
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Abstract
The invention provides an environment-friendly infusion soft bag, which belongs to medical articles. The environment-friendly infusion soft bag is made by incorporating a modifier into polypropylene and comprises at least three layers, wherein a first layer consists of modified polypropylene; the addition amount of the modifier in the first layer is 60 percent at most; the thickness of the first layer accounts for not more than 25 percent of that of an entire structure; a second layer mutually lapping the first layer consists of the modified polypropylene; the addition amount of the modifier in the second layer is 80 percent at most; the thickness of the second layer accounts for 50 to 80 percent of that of the entire structure; furthermore, a third layer consists of the modified polypropylene and mutually laps the second layer; the second layer is positioned between the first layer and the third layer; the addition amount of the modifier in the third layer is 70 percent at most; the thickness of the second layer accounts for not more than 25 percent of that of the entire structure; and then the environment-friendly infusion bag with high transparency and enough thermal-sealing strength can be obtained. The bag has the advantages that the bag has enough mechanical properties and capability of preventing water and steam, can be thermally sealed, has enough strength, and is stable in performances, resistant to high temperature, easy to sterilize and high in transparency.
Description
Technical field
The present invention relates to the medical container class, particularly a kind of environment-friendly type infusion soft bag refers to especially a kind ofly be used for filling solution and inject intravital disposable medical container, and is the making of non-PVC multi-layer film and the environment-friendly type infusion soft bag of composition.
Background technology
In nineteen sixty, developed countries such as Europe, the United States, day begin to adopt the DEHP plasticized PVC, make the Dispoable medical infusion apparatus afterwards after, various countries also begin large-scale promotion application, China is no exception.Yet in recent years along with clinical practice extensively, go deep into and the relevant medical science and technology development, it is found that itself there is potential safety hazard in the PVC material, all deficiencies are also arranged on the serviceability, for example: contain 40% ~ 60% plasticizer DEHP in the flexible PVC material, with calcium, the stabilizing agent that zinc and barium etc. are elementary composition, deposit with use in can pull the surface of infusion apparatus, pollute medicinal liquid and blood products, and may enter human body with infusion process, cause potential harm or make the patient in therapeutic process, increase new etiology to patient health, in addition, the waste treatment of PVC transfusion flexible bag serious environment pollution also.
Multilayer technique has been widely used in industries such as food industry, high-tech industry and pharmaceutical sector at present, in recent years for fear of the doubt of people to PVC, also begin multilayer technique is used in the making of transfusion flexible bag, and relevant patent is ten hundreds of especially, and below be and the similar case of the application's case:
A kind of PVC that do not contain of record in DE19515254C2, but handle and immovable basically multilayer film behind pasteurization taking the photograph under formula 121 degree pasteurization at least; This film has trilaminar structure and is made up of pure material or the mixture of polypropylene homopolymer, LDPE, SEBS, S.IS and PIB.Skin and internal layer compare at 1:4.5 between the 1:9 the thickness in intermediate layer.
In EPO929475B1, mention a kind of multilayer film with two mutual bonding coats, wherein ground floor is made up of polypropylene, polyethylene and ethylene copolymers and a kind of modification agent, and the second layer by polypropylene with different before the modification agent of one decks forms, but because this kind prescription has used poly one-tenth branch to make weldability, transparent and bactericidal properties defective occur.
But mentioned the multilayer film that a kind of high frequency welds in WO9513918, this kind film is formed ground floor by polypropylene copolymer and SEBS block copolymer, and bonding coat then is made up of the polymer that polypropylene, a kind of high frequency of non-polypropylene Polyolefin and weld.
Mention a kind of multi-layer film structure with layer 2-4 in EPO301773A2, all layers all have any copolymer of polypropylene and ethylene-1-butylene copolymer and may provide the 3rd layer of elastic property to form; Therefore in the method,, in outer and sealant, have only very little temperature contrast, therefore cause when a large amount of bag, can't having and stablize and the performance of quick welding owing to all forms in each layer by similar component.
In WO9836905, put down in writing a kind of multi-layer film structure, this kind multilayer film be by polypropylene as skin, internal layer then uses poly-third ethylene or polyethylene and ethylene copolymers, the different polyethylene and ethylene copolymers of softening point is then adopted in other intermediate layer; Owing to there are a lot of intermediate layers, so the membranous type attitude is quite complicated, and the interface may produce layering effect, is that negative influence is arranged for the multilayer film that needs pasteurization therefore.
Mention in US6027776 and use a kind of five layers multi-layer film structure, its skin is made up of polypropylene, high density polyethylene (HDPE) or copolyesters; Other layer used materials such as comprising polyamide homopolymer or copolymer, copolyesters, high density polyethylene (HDPE), polypropylene copolymer to form, this kind structure with form comparatively complicatedly, and pliability is also harder compared to traditional PVC transfusion flexible bag.
The problem of above-mentioned existence needs further to improve with disappearance.
Summary of the invention
The object of the present invention is to provide a kind of environment-friendly type infusion soft bag, it mixes polypropylene by modifier, adds hydrogenation polystyrene-polybutadiene three block block copolymers and has printing and resist characteristics such as stinging saturating property to reach; Add hydrogenated polystyrene-polybutadiene three block block copolymer and polypropylene elastomers, have flexibility and mechanical performance to reach, and improve the resistance to low temperature of thin film; Add polypropylene elastomer, have the high good characteristic of heat seal strength to reach.
Technical scheme of the present invention is:
A kind of environment-friendly type infusion soft bag mixes polypropylene by modifier, and comprises three layers at least:
Ground floor is made up of the polypropylene of modification, the as many as 60% of its modifier addition, and the thickness of ground floor accounts for the as many as 25% of overall structure thickness;
The second layer is made up of the polypropylene of modification, and stacked mutually with ground floor, and between ground floor and the 3rd layer.The as many as 80% of its modifier addition, and its thickness accounts for integrally-built 50 ~ 80%;
The 3rd series of strata are made up of the polypropylene of modification, and stacked mutually with the second layer, the as many as 70% of its modifier addition, and its thickness accounts for the as many as 25% of overall structure thickness.
In addition, the polypropylene of each layer all is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed.
The employed modifier of the polypropylene of modification can be styrene block copolymer/any copolymer or one of them person of polypropylene elastomer.
Styrene block copolymer/any copolymer, it is to be selected from the group that polystyrene-polybutadiene two block block copolymers (SB), polystyrene-polybutadiene three block block copolymers (SBS), many blocks of polystyrene-polybutadiene block copolymer (SBn), polystyrene-polyisoprene two block block copolymers (SI), polystyrene-polyisoprene three block block copolymers (SIS) or many blocks of polystyrene-polyisoprene block copolymer (SIn) are formed.
Polypropylene elastomer system is made of ethylene contents at least 45% via coordination polymerization propylene and ethylene.
Assembly of thin films adopts the water-cooled bottom blowing type to press inflation film manufacturing machine altogether, and making its whole gross thickness is 180 μ m.
The thickness of the second layer accounts for whole gross thickness 50 ~ 80%, and this ground floor and the 3rd layer account for whole gross thickness maximum 25% in addition.
The invention has the advantages that the soft transfusion bag of environment-friendly type of the present invention has enough mechanical performances and blocks water and the ability of steam, and stable performance, and can high temperature resistant (or taking the photograph formula 121 degree, 25 minutes) so that sterilization treatment; Also has high transparent; Can seal and have enough heat seal strengths, not have the fluid seepage phenomenon after the heat-sealing.
Description of drawings:
Fig. 1 is a block schematic diagram of the present invention;
The specific embodiment:
Embodiment 1
As shown in Figure 1, a kind of environment-friendly type infusion soft bag of the present invention is plural layers, and multilayer film comprises:
1) ground floor is made up of the polypropylene of modification, its modifier addition maximum 60%, and the thickness of ground floor is 10% of overall structure thickness 180 μ m, and polypropylene-basedly is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed; In addition, add the interior modifier of polypropylene based on styrene block copolymer/any copolymer or one of them person of polypropylene elastomer, wherein, styrene block copolymer/the copolymerization system is selected from polystyrene-polybutadiene two block block copolymers (SB) arbitrarily, polystyrene-polybutadiene three block block copolymers (SBS), many blocks of polystyrene-polybutadiene block copolymer (SBn), polystyrene-polyisoprene two block block copolymers (SI), the group that polystyrene-polyisoprene three block block copolymers (SIS) or many blocks of polystyrene-polyisoprene block copolymer (SIn) are formed, and polypropylene elastomer is made up of via coordination polymerization propylene and ethylene, above-mentioned ethylene contents at least 45%.
Selecting polypropylene homopolymer and its content for use when polypropylene is 97%, it is 3% that modifier is then selected hydrogenation polyethylene-polybutadiene three block block copolymers and its content in the copolymer of styrene block copolymer/arbitrarily for use, and nationality is arranged in pairs or groups thus and can be allowed characteristics such as ground floor tool thermostability, printing and puncture resistance.
2) second layer is stacked mutually with ground floor, and the polypropylene by modification is formed, the as many as 80% of its modifier addition, and its thickness is 80% of overall structure 180 μ m, and polypropylene-basedly is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed; In addition, add the interior modifier of polypropylene with styrene block copolymer/any copolymer or one of them person of polypropylene elastomer, wherein, styrene block copolymer/the copolymerization system is selected from polystyrene-polybutadiene two block block copolymers (SB) arbitrarily, polystyrene-polybutadiene three block block copolymers (SBS), many blocks of polystyrene-polybutadiene block copolymer (SBn), polystyrene-polyisoprene two block block copolymers (SI), the group that polystyrene-polyisoprene three block block copolymers (SIS) or many blocks of polystyrene-polyisoprene block copolymer (SIn) are formed, and polypropylene elastomer is made up of via coordination polymerization propylene and ethylene, above-mentioned ethylene contents at least 45%.
Selecting any copolymer of polypropylene and its content for use when polypropylene is 75%, modifier then select for use hydrogenated polystyrene-polybutadiene three block block copolymers in the copolymer of styrene block copolymer/arbitrarily and its content be 20% and polypropylene elastomer and its content be 5%, nationality is arranged in pairs or groups thus and can be allowed ground floor have flexibility and mechanical performance, and improves the resistance to low temperature of thin film.
3) the 3rd series of strata are made up of the polypropylene of modification, and it is stacked mutually with the second layer, the second layer is then between ground floor and the 3rd layer, the as many as 70% of its 3rd layer of modifier addition, and its thickness is integrally-built 10%, and polypropylene is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed; In addition, add the interior modifier of polypropylene with styrene block copolymer/any copolymer or one of them person of polypropylene elastomer, wherein, styrene block copolymer/the copolymerization system is selected from polystyrene-polybutadiene two block block copolymers (SB) arbitrarily, polystyrene-polybutadiene three block block copolymers (SBS), many blocks of polystyrene-polybutadiene block copolymer (SBn), polystyrene-polyisoprene two block block copolymers (SI), the group that polystyrene-polyisoprene three block block copolymers (SIS) or many blocks of polystyrene-polyisoprene block copolymer (SIn) are formed, and polypropylene elastomer is made up of via coordination polymerization propylene and ethylene, above-mentioned ethylene contents at least 45%.
Selecting polypropylene homopolymer and its content for use when polypropylene is 92%, and modifier is selected the hydrogenated polystyrene in the copolymer of styrene block copolymer/arbitrarily for use--polybutadiene three block block copolymers and its content be 3% and polypropylene elastomer and its content be 5%,, nationality is arranged in pairs or groups thus and can be allowed ground floor have heat seal strength height, anti-steaming and decocting and block-water performance excellent characteristic.
Embodiment 2
Below will describe the environment-friendly type infusion soft bag that the present invention is made into according to different proportion and content in detail, environment-friendly type infusion soft bag of the present invention is a kind of plural layers.
1) ground floor is made up of the polypropylene of modification, the as many as 60% of its modifier addition, and the thickness of ground floor accounts for 10% of overall structure thickness 180 μ m, when polypropylene-based polypropylene homopolymer and its content selected for use is 97%, modifier is then selected hydrogenated polystyrene-polybutadiene three block block copolymers and its content 3% in the copolymer of styrene block copolymer/arbitrarily for use, and nationality is arranged in pairs or groups thus and can be allowed characteristics such as ground floor tool thermostability, printing and puncture resistance.
2) second layer is stacked mutually with ground floor, and the polypropylene by modification is formed, the as many as 80% of its modifier addition, and its thickness is 55% of overall structure 180 μ m, when polypropylene is selected any copolymer of polypropylene and its content 65% for use, modifier then select for use hydrogenated polystyrene-polybutadiene three block block copolymers in the copolymer of styrene block copolymer/arbitrarily and its content be 30% and polypropylene elastomer and its content be 5%, nationality is arranged in pairs or groups thus and can be allowed ground floor have flexibility and mechanical performance, and improves the resistance to low temperature of thin film.
3) the 3rd series of strata are made up of the polypropylene of modification, and it is stacked mutually with the second layer, the second layer is then between ground floor and the 3rd layer, the as many as 70% of its 3rd layer of modifier addition, and its thickness is integrally-built thickness 35%, selecting any copolymer of polypropylene and its content for use when polypropylene is 75% and modifier is selected the hydrogenated polystyrene-polybutadiene three block block copolymers in the copolymer of styrene block copolymer/arbitrarily for use, and its content be 15% and polypropylene elastomer and its content be 10%, nationality is arranged in pairs or groups thus and can be allowed ground floor have heat seal strength height and block-water performance excellent characteristic.
Claims (7)
1, a kind of environment-friendly type infusion soft bag, it is characterized in that: it mixes polypropylene by modifier, and comprises three layers at least:
A, ground floor are made up of the polypropylene of modification, its modifier addition is maximum 60%, and this polypropylene-basedly is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed;
B, the second layer are made up of the polypropylene of modification, and it is stacked mutually with ground floor, it is maximum 80% that its modifier adds, and this polypropylene-basedly is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed;
C, the 3rd series of strata are made up of the polypropylene of modification, and it is mutually stacked with the second layer, make the second layer between ground floor and the 3rd layer, its modifier addition is maximum 70%, and this polypropylene-basedly is selected from the group that polypropylene homopolymer, any copolymer of polypropylene, polypropylene terpolymer, high anti-impulsing polypropylene, high-crystallinity polypropylene or high transparent polypropylene are formed.
2, according to the described a kind of environment-friendly type infusion soft bag of claim 1, it is characterized in that: the employed modifier of the polypropylene of described modification can be styrene block copolymer/any copolymer or one of them person of polypropylene elastomer.
3, according to according to the described a kind of environment-friendly type infusion soft bag of claim 2, it is characterized in that: described styrene block copolymer/any copolymer, it is to be selected from the group that polystyrene-polybutadiene two block block copolymers, polystyrene-polybutadiene three block block copolymers, many blocks of polystyrene-polybutadiene block copolymer, polystyrene-polyisoprene two block block copolymers, polystyrene-polyisoprene three block block copolymers or many blocks of polystyrene-polyisoprene block copolymer are formed.
4, according to the described a kind of environment-friendly type infusion soft bag of claim 2, it is characterized in that: described polypropylene elastomer is made up of via coordination polymerization propylene and ethylene.
5, according to the described a kind of environment-friendly type infusion soft bag of claim 4, it is characterized in that: described ethylene contents at least 45%.
6, according to the described a kind of environment-friendly type infusion soft bag of claim 1, it is characterized in that: described assembly of thin films adopts the water-cooled bottom blowing type to press inflation film manufacturing machine altogether, and making its whole gross thickness is 180 μ m.
7, according to the described a kind of environment-friendly type infusion soft bag of claim 1, it is characterized in that: the thickness of the described second layer accounts for whole gross thickness 50 ~ 80%, and this ground floor and the 3rd layer account for whole gross thickness maximum 25% in addition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100041602A CN101485613A (en) | 2009-02-13 | 2009-02-13 | Environment-friendly type infusion soft bag |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2009100041602A CN101485613A (en) | 2009-02-13 | 2009-02-13 | Environment-friendly type infusion soft bag |
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| Publication Number | Publication Date |
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| CN101485613A true CN101485613A (en) | 2009-07-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2009100041602A Pending CN101485613A (en) | 2009-02-13 | 2009-02-13 | Environment-friendly type infusion soft bag |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102321298A (en) * | 2011-08-03 | 2012-01-18 | 中山市长健医用包装材料有限公司 | A kind of infusion bag that is used for is with the outer field polypropylene granules of film |
| CN103893012A (en) * | 2014-03-25 | 2014-07-02 | 安徽双鹤药业有限责任公司 | Three-layer medical infusion bag and manufacturing method thereof |
| CN113081828A (en) * | 2021-03-31 | 2021-07-09 | 山东永聚医药科技有限公司 | New use of polypropylene material |
-
2009
- 2009-02-13 CN CNA2009100041602A patent/CN101485613A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102321298A (en) * | 2011-08-03 | 2012-01-18 | 中山市长健医用包装材料有限公司 | A kind of infusion bag that is used for is with the outer field polypropylene granules of film |
| CN103893012A (en) * | 2014-03-25 | 2014-07-02 | 安徽双鹤药业有限责任公司 | Three-layer medical infusion bag and manufacturing method thereof |
| CN103893012B (en) * | 2014-03-25 | 2016-09-14 | 安徽双鹤药业有限责任公司 | A kind of three layers of medical infusion bags and manufacture method thereof |
| CN113081828A (en) * | 2021-03-31 | 2021-07-09 | 山东永聚医药科技有限公司 | New use of polypropylene material |
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Open date: 20090722 |