CN103893012B - A kind of three layers of medical infusion bags and manufacture method thereof - Google Patents
A kind of three layers of medical infusion bags and manufacture method thereof Download PDFInfo
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Abstract
It is an object of the invention to provide a kind of three layers of medical infusion bags, flat transfusion bag body including three-decker, three-decker includes the interior bag layer of polythene material, polypropylene and the middle bag layer of styrene-ethylene/butylene-styrene block copolymer material and polypropylene, carboxylated styrene's ethylene/butylene-styrene block copolymer, the outer bag layer of nano composite material of anionic polymerization nylon blended layer, the nano composite material of anionic polymerization nylon barrier of outer bag layer is superior；It is good that the thickness width design of transfusion bag body can make infusion process can empty whole transfusion bag safety compared with the gravity flow of constant speed without air inlet medicinal liquid, and good barrier property, transfusion performance is good；Also providing for the manufacture method of a kind of three layers of medical infusion bags, use three die head injection molds be once molded and blow, whole technique is the most advanced, once-forming, is suitable for the production of this transfusion bag, and the transfusion bag made meets the requirement of transfusion.
Description
Technical field
The present invention relates to the field of Medical transfusion container, particularly relate to a kind of safer medical infusion bags and the method manufacturing this transfusion bag.
Background technology
At present, Medical transfusion container has plastic bottle, co-extrusion infusion film and blended transfusion bag several types.Following is a brief introduction of content and its weak point of these several infusion vessels:
The plastic bottle announced such as patent No. CN 201759852 U is lightweight, with medicinal liquid, there is the fine compatibility, but still there is in terms of infusion model the defect of vial, need air inlet, thus resulting in harmful antibacterial and the possibility of microgranule increase in bottle, therefore the development of plastic bottle is restricted.
The co-extrusion infusion film that and for example patent No. CN 101462389 A announces, is the film of three layers, has good temperature tolerance, excellent clarity, broad heat-sealing temperature scope, the pliability of high and low temperature environment, the good compatibility, but internal layer is polypropylene, outer layer does not has barrier layer, is to use coextrusion process, expensive, production cost is high, and leakage is its fault of construction.
The blend composition transfusion bag that and for example patent No. CN 102397160 A announces, this transfusion bag bag has lightweight, low cost, quality height, the feature of integrated molding, in use without air inlet, employing atmospheric pressure is infused, but transfusion flexible bag is the bag of the blend composition of only a layer or two-layer, material transport relevant with medicinal liquid contact layer is to medicinal liquid, and its safety and barrier need to be considered.
The patent of invention of one Patent No. CN 101411672 B of the applicant, disclose a kind of medical infusion soft bag and manufacture method thereof and method for shaping, the polypropylene combination cover of transfusion bag mouth cooperation outsourcing, fusing point is not quite identical with bag material, takes and checks its sealing by fusing effect quarter；Added with toughened plastics in transfusion bag raw material, expensive, safety is the lowest；Transfusion bag be flat and the width ratio with thickness directly affect medicinal liquid more than or equal to 3 certainly empty performance；Transfusion bag side is smooth curved surface circular arc, is unfavorable for the emptying certainly of medicinal liquid；Transfusion bag body is flexible plastic, and the dies cavity that transfusion bag body be placed on respective shapes obtains sizing；Draw-ring type polypropylene combination cover, it may appear that draw ring is easily broken, be difficult to pull open, during sterilizing, at draw ring, water vapour easily penetrates into, and pollutes；Simultaneously its production technology one-step method (note stretch blow, just for bag, do not include composite cover) or two step method (injection, bag) is the most complex and easy infection foreign body.The patent of invention of another patent No. CN 103519991 A of the applicant, disclose a kind of Novel plastic infusion bag and manufacture method thereof, it is a kind of simple in construction, low cost of manufacture, transfusion bag can be allowed need not to add air inlet needle when transfusion, when infusing with non-air admission type transfusion needle, completely can from emptying and will not blood back, bag shape there will not be more serious deformation and the transfusion bag that can stably stand；But this transfusion bag is one layer, it becomes the relevant material of component polypropylene can move to medicinal liquid, and its safety, barrier needs to be considered.
The patent of invention of one patent No. CN 1415644 A of the applicant, discloses a kind of nano composite material of anionic polymerization nylon, and its intensity is high, and good rigidly, barrier property is superior, dimensionally stable, and technique is simple, efficiency is high；According to the shortcoming of several infusion vessels introduced before, the material that present invention employs above-mentioned patent carries out bag, is thus reaches high barrier, and especially a kind of nano composite material of anionic polymerization nylon, it acts primarily as iris action.
Summary of the invention
The present invention provides a kind of safe medical transfusion flexible bag and manufacture method thereof, by arranging the transfusion bag of three layers of bag Rotating fields and providing corresponding production method, improves stability, safety and barrier, solves produced problem in background technology.
It is an object of the invention to provide a kind of three layers of medical infusion bags, mainly transfusion bag body, the width of transfusion bag body is more than thickness (being flat shape), and transfusion bag body is combined by three-decker, and three layers are respectively interior bag layer, middle bag layer and outer bag layer；Wherein interior bag layer is namely the material of polyethylene with medicinal liquid contact layer, middle bag layer is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer namely layer with extraneous contact is polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material；Having bag mouth at the top of transfusion bag body, the bottom interposition of transfusion bag body is equipped with the hanged hook of convenient suspension；The most also transfusion bag body outer peripheral face is provided with snap lock taut band.
Further improvement is that: the cervical region of transfusion bag body is flat shoulder, it is not possible to for circle, median surface thickness is 0.18 ~ 0.2mm, and neck side thickness is the 3/4 of median surface thickness；The thickness of transfusion bag body both sides is the 3/4 of median surface thickness, and its width is 0.8 ~ 1.2mm, is so conducive to from emptying.
Further improvement is that: middle bag layer can be compatible with outer bag layer, interior bag layer, thus is bonded together with interior bag layer by outer bag layer, and three-decker becomes the structure being integrated.
Further improvement is that: the polypropylene of described middle bag layer and the mass ratio (50 ~ 90) of styrene-ethylene/butylene-styrene block copolymer: (5 ~ 55).
Further improvement is that: the mass ratio of the polypropylene of described outer bag layer, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer is (50 ~ 90): (3 ~ 10): (7 ~ 40).
Further improvement is that: described middle bag layer may be used without polypropylene and adds octene block copolymer or polypropylene and ethylene propylene diene rubber with ethylene, wherein polypropylene: ethylene adds the mass ratio (50 ~ 90) of octene block copolymer: (5 ~ 55), polypropylene: the mass ratio (50 ~ 90) of ethylene propylene diene rubber: (5 ~ 55).
Further improvement is that: the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer need to use bulking agent to make it compatible, the present invention uses carboxylated styrene-ethylene/butylene-styrene block copolymer as bulking agent.
Further improvement is that: the bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer may be used without Carboxylation ethylene and octene block copolymer or Carboxylation ethylene propylene diene rubber.
The manufacture method of a kind of three layers of medical infusion bags, comprises the following steps:
Step one: the material making interior bag layer, middle bag layer and the polythene material of outer bag layer, polypropylene and the polypropylene of styrene-ethylene/butylene-styrene block copolymer material, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer respectively is purified respectively and is prepared according to given formula, and every kind of material stirs mixing 10 ~ 12min respectively afterwards；
Step 2: injection mold is preheated, the material of three bag layers step one preparation mixed adds heat fusing respectively, temperature is 250 ~ 280 DEG C, and the thick liquid material of three bag layer materials after melting is injected in mould by three die heads respectively and is molded into interior bag layer, middle bag layer and the bag embryo of outer bag layer；
Step 3: the bag embryo of three layers step 2 formed places cooling forming；
Step 4: the bag embryo of three layers step 3 be cooled into carries out blowing bag and processes, and air blowing air pressure is 1.5 ~ 1.8MPa, just can be blow molded into the transfusion bag of required three layer；
Step 5: carry out liquid drug；
Step 6: liquid drug is complete, seals.
Beneficial effects of the present invention: by arranging the interior bag layer of full-closed structure, middle bag layer and outer bag layer；It is polyethylene with medicinal liquid contact layer, the most general polypropylene safety of ratio, additive-free move in medicinal liquid；Outer bag layer uses the nano composite material of anionic polymerization nylon with high-barrier declaring patent of independent research as barrier layer simultaneously, substantially increases bag resistance oxygen, block-water performance, improves the safety of medicinal liquid；And also it is provided with the middle bag layer of polypropylene, styrene-ethylene/butylene-styrene block copolymer layer, outer bag layer is bonded together with interior bag layer.The design of the soft transfusion bag of three layers, makes whole transfusion bag security performance better；The technique of this transfusion bag uses injection, stretching, the technique of air blowing, this technique uses three die head injection molds to carry out an integrated injection and is moulded embryonic type, and technique is advanced, and craftsmenship is strong, require height without complicated the production as co-extrusion film, overcome the fault of construction of PP TYPE leakage；The bottom of transfusion bag body is provided with hanged hook, makes transfusion convenient；Be vertically disposed with snap lock taut band on transfusion bag body surface, snap lock taut band can be loaded onto photoelectric liquid level sensor, photoelectric liquid level sensor and liquid level observation system and connect together, and the most just can sense the liquid level of transfusion bag at any time, and infusion process makes patient safer；Whole transfusion bag body is flat shape, such is designed beautifully, and a spike is arranged at the bottom of bag, the most just can uprightly stand and be easy to dosing in the plane；The ratio that the liquid of bag takes up room with reserved dosing space simultaneously is 1:1.0 1:1.7, the cervical region of transfusion bag body is flat shoulder, median surface thickness is 0.18 ~ 0.2mm, neck side thickness is the 3/4 of median surface thickness, so be conducive to from emptying and also flow velocity is uniform, the thickness of both sides is the 3/4 of median surface thickness, its width is 0.8 ~ 1.2mm, the most just after medicinal liquid can be made to flow out, the volume of bag diminishes, thus pressure becomes big, so be conducive to from emptying, infusion process without air inlet medicinal liquid can relatively constant speed gravity flow emptying；In sum, the transfusion bag appearance looks elegant of the present invention, safety is good, good barrier property, and transfusion performance is good, and it is more convenient to use, it is adaptable in medical infusion；The transfusion bag manufacturing approach craft of the present invention is advanced, once-forming, is suitable for the production of this transfusion bag.
Accompanying drawing explanation
Fig. 1 is the front view of the present invention.
Fig. 2 is the partial section view that the present invention looks up.
Wherein: 1-transfusion bag body, 2-interior bag layer, bag layer in 3-, 4-outer bag layer, 5-bag mouth, 6-hanged hook, 7-snap lock taut band.
Detailed description of the invention
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, and this embodiment is only used for explaining the present invention, is not intended that limiting the scope of the present invention.
Embodiment one:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, including interior bag layer 2, middle bag layer 3 and outer bag layer 4；The layer that described interior bag layer 2 contacts with medicinal liquid exactly is polythene material, middle bag layer 3 is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 layer with extraneous contact exactly is polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material；Crown center at transfusion bag body 1 has bag mouth 5；Hanged hook 6 is had in the middle of outside the bottom of described transfusion bag body 1；The flexible locking belt of transfusion bag body 1 outer peripheral face 7.The cervical region of transfusion bag body is flat shoulder, and median surface thickness is 0.18mm, and neck side thickness is the 3/4 of median surface thickness；The thickness of transfusion bag body 1 both sides is the 3/4 of median surface thickness, and its width is 0.8mm, is so conducive to from emptying.Middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, are bonded together with interior bag layer 2 by outer bag layer 4.The polypropylene of middle bag layer 3 and the mass ratio 60:40 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of the polypropylene of outer bag layer 4, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer is 60:5:35.Middle bag layer 3 may be used without polypropylene and adds octene block copolymer or polypropylene and ethylene propylene diene rubber with ethylene, and wherein polypropylene and ethylene add the mass ratio 60:40 of the mass ratio 60:40 of octene block copolymer, polypropylene and ethylene propylene diene rubber.Outer bag layer 4 uses carboxylated styrene-ethylene/butylene-styrene block copolymer as the bulking agent of polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 may be used without Carboxylation ethylene and octene block copolymer or Carboxylation ethylene propylene diene rubber.
Embodiment two:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, including interior bag layer 2, middle bag layer 3 and outer bag layer 4；The layer that described interior bag layer 2 contacts with medicinal liquid exactly is polythene material, middle bag layer 3 is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 layer with extraneous contact exactly is polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material；Crown center at transfusion bag body 1 has bag mouth 5；Hanged hook 6 is had in the middle of outside the bottom of described transfusion bag body 1；The flexible locking belt of transfusion bag body 1 outer peripheral face 7.The cervical region of transfusion bag body 1 is flat shoulder, it is not possible to for circle, median surface thickness is 0.19mm, and neck side thickness is the 3/4 of median surface thickness；The thickness of transfusion bag body both sides is the 3/4 of median surface thickness, and its width is 1.0mm, is so conducive to from emptying.Middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, are bonded together with interior bag layer 2 by outer bag layer 4.The polypropylene of middle bag layer 3 and the mass ratio 75:25 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of the polypropylene of outer bag layer 4, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer is 75:7:18.Middle bag layer 3 may be used without polypropylene and adds octene block copolymer or polypropylene and ethylene propylene diene rubber with ethylene, and wherein polypropylene and ethylene add the mass ratio 75:25 of the mass ratio 75:25 of octene block copolymer, polypropylene and ethylene propylene diene rubber.Outer bag layer 4 uses carboxylated styrene-ethylene/butylene-styrene block copolymer as the bulking agent of polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 may be used without Carboxylation ethylene and octene block copolymer or Carboxylation ethylene propylene diene rubber.
Embodiment three:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, including interior bag layer 2, middle bag layer 3 and outer bag layer 4；The layer that described interior bag layer 2 contacts with medicinal liquid exactly is polythene material, middle bag layer 3 is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 layer with extraneous contact exactly is polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material；Crown center at transfusion bag body 1 has bag mouth 5；Hanged hook 6 is had in the middle of outside the bottom of described transfusion bag body 1；The flexible locking belt of transfusion bag body 1 outer peripheral face 7.The cervical region of transfusion bag body is flat shoulder, and median surface thickness is 0.20mm, and neck side thickness is the 3/4 of median surface thickness；The thickness of transfusion bag body 1 both sides is the 3/4 of median surface thickness, and its width is 1.20mm, is so conducive to from emptying.Middle bag layer 3 and outer bag layer 4, interior bag layer 2 are compatible, are bonded together with interior bag layer 2 by outer bag layer 4.The polypropylene of middle bag layer 3 and the mass ratio 85:15 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of the polypropylene of outer bag layer 4, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer is 85:4:11.Middle bag layer 3 may be used without polypropylene and adds octene block copolymer or polypropylene and ethylene propylene diene rubber with ethylene, and wherein polypropylene and ethylene add the mass ratio 85:15 of the mass ratio 85:15 of octene block copolymer, polypropylene and ethylene propylene diene rubber.Outer bag layer 4 uses carboxylated styrene-ethylene/butylene-styrene block copolymer as the bulking agent of polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 may be used without Carboxylation ethylene and octene block copolymer or Carboxylation ethylene propylene diene rubber.
Embodiment four:
The present embodiment provides the manufacture method of a kind of three layers of medical infusion bags, comprises the following steps:
Step one: will make the material of three layers respectively: polythene material, polypropylene and styrene-ethylene/butylene-styrene block copolymer material and polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer are purified respectively and prepare by the formula formulated, the most respectively stirring mixing 10min；
Step 2: injection mold is preheated, the material of three bag layers preparation stirring mixed adds heat fusing respectively, temperature is 265 DEG C, will melted after the thick liquid material of three bag layer materials be injected in mould by three die heads respectively and be molded into three-decker and i.e. contain interior bag layer 2, middle bag layer 3 and the bag embryo of outer bag layer 4；
Step 3: the bag embryo of three layers step 2 formed places cooling forming；
Step 4: carrying out blowing bag in the bag embryos of the three of cooling forming layers are sent into air feeder, air blowing air pressure is 1.6MPa, is blow molded into the transfusion bag of required three layer；
Step 5: by solid-liquid ratio liquid drug；
Step 6: liquid drug is complete, finally seals.
In sum, four embodiment transfusion bag all can reach transfusion requirement.
By arranging the interior bag layer 2 of full-closed structure, middle bag layer 3 and outer bag layer 4；It is polyethylene with medicinal liquid contact layer, the most general polypropylene safety of ratio, additive-free move in medicinal liquid；Outer bag layer 4 uses independent research to have the nano composite material of anionic polymerization nylon of high-barrier as barrier layer simultaneously, substantially increases bag resistance oxygen, block-water performance, improves the safety of medicinal liquid；And also it is provided with the middle bag layer 3 of polypropylene, styrene-ethylene/butylene-styrene block copolymer layer, outer bag layer 4 is bonded together with interior bag layer 2.The design of the soft transfusion bag of three layers, makes whole transfusion bag security performance better；The bottom of transfusion bag body is provided with hanged hook 6, makes transfusion convenient；Be vertically disposed with snap lock taut band 7 on transfusion bag body surface, snap lock taut band 7 can be loaded onto photoelectric liquid level sensor, photoelectric liquid level sensor and liquid level observation system and connect together, and the most just can sense the liquid level of transfusion bag at any time, and infusion process makes patient safer；Whole transfusion bag body 1, in flat shape, such is designed beautifully, and a spike is arranged at the bottom of bag, the most just can uprightly stand and be easy to dosing in the plane；The ratio that the liquid of bag takes up room with reserved dosing space simultaneously is 1:1.4, the cervical region of transfusion bag body 1 is flat shoulder, neck side thickness is the 3/4 of median surface thickness, so be conducive to from emptying and also flow velocity is uniform, the thickness of both sides is the 3/4 of median surface thickness, and after medicinal liquid the most just can be made to flow out, the volume of bag diminishes, thus pressure becomes big, so be conducive to from emptying, infusion process without air inlet medicinal liquid can relatively constant speed gravity flow emptying；The technique of this transfusion bag uses injection, stretching, the technique blown, this technique uses three die head injection molds to carry out an integrated injection and is moulded embryonic type, and technique is advanced, and craftsmenship is strong, height is required without complicated the production as co-extrusion film, overcome the fault of construction of PP TYPE leakage, and make transfusion bag meets the requirement of transfusion, can more play the performance of material compared with technique before；In sum, the transfusion bag appearance looks elegant of the present invention, safety is good, good barrier property, and transfusion performance is good, and it is more convenient to use, it is adaptable in medical infusion；The transfusion bag manufacturing approach craft of the present invention is advanced, once-forming, is suitable for the production of this transfusion bag.
Claims (10)
1. three layers of medical infusion bags, including transfusion bag body (1), it is characterised in that: described transfusion bag body (1) is that the width of flat shape, i.e. bag is more than thickness, transfusion bag body (1) is three-decker, including interior bag layer (2), middle bag layer (3) and outer bag layer (4)；Described interior bag layer (2) is polythene material, middle bag layer (3) is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer (4) is polypropylene, carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material；The crown center of described transfusion bag body (1) is provided with bag mouth (5)；The bottom of described transfusion bag body (1) is outside equipped with hanged hook (6)；Described transfusion bag body (1) outer peripheral face is provided with snap lock taut band (7).
2. as claimed in claim 1 a kind of three layers of medical infusion bags, it is characterised in that: described middle bag layer (3) and outer bag layer (4), interior bag layer (2) are compatible, thus are bonded together with interior bag layer (2) by outer bag layer (4).
3. a kind of three layers of medical infusion bags, it is characterised in that: the neck portion of described transfusion bag body (1) is flat shoulder, and median surface thickness is 0.18 ~ 0.2mm, and neck side thickness is the 3/4 of median surface thickness.
4. a kind of three layers of medical infusion bags, it is characterised in that: the thickness of described transfusion bag body (1) both sides is the 3/4 of median surface thickness.
5. a kind of three layers of medical infusion bags, it is characterised in that: the polypropylene of described middle bag layer (3) and the mass ratio (50 ~ 90) of styrene-ethylene/butylene-styrene block copolymer: (5 ~ 55).
6. a kind of three layers of medical infusion bags, it is characterised in that: the mass ratio of the polypropylene of described outer bag layer (4), carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer is (50 ~ 90): (3 ~ 10): (7 ~ 40).
7. a kind of three layers of medical infusion bags, it is characterized in that: the polypropylene of described middle bag layer (3) and styrene-ethylene/butylene-styrene block copolymer material replace with polypropylene and ethylene and add octene block copolymer, or polypropylene and ethylene propylene diene rubber；Wherein polypropylene: ethylene adds the mass ratio (50 ~ 90) of octene block copolymer: (5 ~ 55), polypropylene: the mass ratio (50 ~ 90) of ethylene propylene diene rubber: (5 ~ 55).
8. a kind of three layers of medical infusion bags, it is characterised in that: described outer bag layer (4) uses carboxylated styrene-ethylene/butylene-styrene block copolymer as the bulking agent of polypropylene/nano composite material of anionic polymerization nylon.
9. a kind of three layers of medical infusion bags, it is characterised in that: the bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer (4) replaces with Carboxylation ethylene and octene block copolymer, or Carboxylation ethylene propylene diene rubber.
10. the manufacture method of three layers of medical infusion bags as claimed in claim 1, it is characterised in that: comprise the following steps:
Step one: the material of polythene material, the polypropylene of middle bag layer (3) and the styrene-ethylene/butylene-styrene block copolymer material and the polypropylene of outer bag layer (4), carboxylated styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer that make interior bag layer (2) is purified respectively and prepares by formula, the most respectively stirring mixing 10 ~ 12min；
Step 2: injection mold is preheated, the material of three bag layers step one preparation mixed adds heat fusing respectively, temperature is 250 ~ 280 DEG C, and the thick liquid material of three bag layer materials after melting is injected in mould by three die heads respectively and is molded into interior bag layer (2), middle bag layer (3) and the bag embryo of outer bag layer (4)；
Step 3: the bag embryo of three layers step 2 formed places cooling forming；
Step 4: the bag embryo of three layers step 3 formed carries out blowing bag in sending into air feeder, and air blowing air pressure is 1.5 ~ 1.8MPa, and the transfusion bag of required three layer is made in blow molding；
Step 5: by the transfusion bag liquid drug of three layers that step 4 prepares；
Step 6: transfusion bag complete for liquid drug is sealed.
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104287964A (en) * | 2014-10-09 | 2015-01-21 | 华润双鹤药业股份有限公司 | Double-layer medical infusion bottle and manufacturing method thereof |
| EP3195845A1 (en) * | 2016-01-21 | 2017-07-26 | B. Braun Melsungen AG | Pharmacy bag with integrated flush option |
| CN106042548B (en) * | 2016-05-13 | 2018-06-19 | 安徽工程大学 | A kind of high-barrier composite bed medical infusion bags |
| CN108058655A (en) * | 2018-01-02 | 2018-05-22 | 温州市环球汽车衬垫有限公司 | A kind of automobile using gusset cavity acoustical cotton and preparation method thereof |
| CN110497671B (en) * | 2019-08-06 | 2021-05-11 | 安徽天润医用新材料有限公司 | High-barrier composite layer medical infusion bag and production method thereof |
| CN113736173A (en) * | 2021-07-28 | 2021-12-03 | 上海乐纯生物技术有限公司 | Cell therapy liquid storage bag and manufacturing method thereof |
| CN114889280B (en) * | 2022-06-17 | 2024-01-02 | 应城市恒天药业包装有限公司 | Disposable high-barrier membrane for intravenous nutrition infusion bag and preparation method thereof |
| CN114851672B (en) * | 2022-07-07 | 2022-09-02 | 山东兰德英科新材料科技有限公司 | Method for preparing infusion bag by adopting biodegradable infusion bag special material |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1415644A (en) * | 2002-08-20 | 2003-05-07 | 刘新华 | Nano composite material of anionic polymerization nylon |
| CN1663775A (en) * | 2005-02-01 | 2005-09-07 | 陈亦锋 | Multilayer co-extrusion transfusion film and manufacturing method thereof |
| CN101485613A (en) * | 2009-02-13 | 2009-07-22 | 邦特生物科技股份有限公司 | Environment-friendly type infusion soft bag |
| CN101903003A (en) * | 2007-12-27 | 2010-12-01 | 巴克斯特国际公司 | Multichamber vessel |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120312711A1 (en) * | 2011-06-10 | 2012-12-13 | Davies Edward A | System and Method for Manufacturing an Improved Film for Medical Supply Packaging |
-
2014
- 2014-03-25 CN CN201410111272.9A patent/CN103893012B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1415644A (en) * | 2002-08-20 | 2003-05-07 | 刘新华 | Nano composite material of anionic polymerization nylon |
| CN1663775A (en) * | 2005-02-01 | 2005-09-07 | 陈亦锋 | Multilayer co-extrusion transfusion film and manufacturing method thereof |
| CN101903003A (en) * | 2007-12-27 | 2010-12-01 | 巴克斯特国际公司 | Multichamber vessel |
| CN101485613A (en) * | 2009-02-13 | 2009-07-22 | 邦特生物科技股份有限公司 | Environment-friendly type infusion soft bag |
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| CN103893012A (en) | 2014-07-02 |
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Inventor after: Liu Xinhua Inventor after: Cao Zongpei Inventor after: Chen Ya Inventor after: Dong Chunhao Inventor after: Qiang Mingming Inventor before: Liu Xinhua Inventor before: Cao Zongpei Inventor before: Chen Ya Inventor before: Dong Chunhao |
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