CN106042548B - A kind of high-barrier composite bed medical infusion bags - Google Patents
A kind of high-barrier composite bed medical infusion bags Download PDFInfo
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- CN106042548B CN106042548B CN201610317554.3A CN201610317554A CN106042548B CN 106042548 B CN106042548 B CN 106042548B CN 201610317554 A CN201610317554 A CN 201610317554A CN 106042548 B CN106042548 B CN 106042548B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2250/00—Layers arrangement
- B32B2250/24—All layers being polymeric
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/40—Properties of the layers or laminate having particular optical properties
- B32B2307/412—Transparent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/724—Permeability to gases, adsorption
- B32B2307/7242—Non-permeable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a kind of high-barrier composite bed medical infusion bags, including transfusion bag body, the transfusion bag body includes interior bag layer, middle bag layer and outer bag layer, the middle bag layer is compatible with outer bag layer, interior bag layer, so as to which outer bag layer be bonded together with interior bag layer, the interior bag layer inner wall of the infusion bag forms transition zone using low temperature magnetic sputtering, the inner wall plating of the transition zone is equipped with barrier layer, the outer wall of the outer bag layer is also plated equipped with barrier layer, and the outer wall of the barrier layer of the outer bag layer forms stenlizing layer using low temperature magnetic sputtering.The present invention prevents the additive of polymeric membrane from moving in drug, serving high barrier, have the function of it is transparent, absorb ultraviolet light and bactericidal effect that is multi-functional, and being used for improving stenlizing layer, while the also effect of progress second protection barrier such as be protected from light.
Description
Technical field
Production technical field more particularly to a kind of high-barrier composite bed medical infusion the present invention relates to a kind of infusion bag
Bag.
Background technology
At present, Medical transfusion container has plastic bottle, co-extrusion infusion film and blending infusion bag several types.It is simple below to be situated between
Continue the content and its shortcoming of these types of infusion vessel：
Plastic bottle as patent No. CN 201759852U are announced is light-weight, has fine compatibility, but infusing with liquid
The defects of in terms of mode or with vial, air inlet is needed, thus causes the increased possibility of bacterium and particle being harmful in bottle,
Therefore the development of plastic bottle is restricted.
The co-extrusion infusion film that for another example patent No. CN 101462389A are announced is three layers of film, has good temperature tolerance,
Excellent clarity, broad heat-sealing temperature range, the flexibility of high and low temperature environment, good compatibility, but internal layer is poly-
Propylene, outer layer do not have barrier layer, are using coextrusion process, expensive, production cost is high, and leakage is its fault of construction.
The blend composition infusion bag that for another example patent No. CN 102397160A are announced, this infusion bag bag have light-weight, cost
It low, the characteristics of quality is high, integrated molding, when in use without air inlet, is infused using atmospheric pressure, but transfusion flexible bag is only
There is the bag of the blend composition of one layer or two layers, related material transport is to liquid, safety and barrier property with liquid contact layer
Need to be considered.
The patent of invention of the Patent No. CN 101411672B of the applicant, discloses a kind of medical infusion soft bag
And its manufacturing method and method for shaping, the polypropylene combination cover for sack cooperation outsourcing of infusing, fusing point and bag body material are incomplete
Unanimously, it takes and checks that it seals effect quarter；Expensive added with toughened plastics in infusion bag raw material, safety is again low；Infusion bag
It is greater than or equal to the 3 emptying performances certainly for directly affecting liquid for flat and the ratio between width and thickness；Infusion bag side is smooth
Curved surface circular arc is unfavorable for emptying certainly for liquid；Transfusion bag body is flexible plastic, and transfusion bag body is placed on to the mould of respective shapes
It is shaped tool inner cavity；Draw-ring type polypropylene combination cover, it may appear that draw ring is easily broken, is difficult to pull open, water vapour at draw ring during sterilizing
It easily penetrates into, pollutes；The one-step method (note stretch blow just for bag body, does not include combined cap) or two steps of its production technology simultaneously
Method (injection, bag making) is complex and easy infection foreign matter.The invention of another patent No. CN103519991A of the applicant
Patent discloses a kind of Novel plastic infusion bag and its manufacturing method, is that one kind is simple in structure, manufacture is at low cost, it is defeated to allow
Liquid bag infusion when do not have to add air tube, when infuse with non-air admission type transfusion needle, completely can from empty and will not blood back, bag body
Shape there will not be the more serious infusion bag deformed and can stablize standing；But the infusion bag is one layer, ingredient poly- third
The related substance of alkene can move to liquid, safety, and barrier property needs to be considered.
The patent of invention of 1415644 A of patent No. CN of the applicant, discloses a kind of anionic polymerization nylon and receives
Nano composite material, intensity is high, and rigidity is good, and barrier property is superior, dimensionally stable, and simple for process, efficient；According to before
The shortcomings that several infusion vessels introduced, the material present invention employs above-mentioned patent carry out bag making, are so as to reach high-barrier
Property, especially a kind of nano composite material of anionic polymerization nylon mainly takes blocking effect.
The patent of invention of the patent No. CN103893012A of the applicant discloses a kind of three layers of medical infusion bags,
It can make volume of liquid outflow back pkt. body become smaller, and become larger so as to pressure, be conducive in this way from emptying, infusion process without into
Gas liquid can be emptied compared with the gravity flow of constant speed, be had a safety feature, good barrier property, and infusion performance is good, and use is more convenient, is used in doctor
With in infusion, and the infusion bag manufacturing approach craft of the present invention is advanced, once-forming, is suitble to the production of this infusion bag.
Existing disclosed patent, technical characteristic is soft bag made of PP TYPE, and additional silica plated film bag is adopted
It is technics comparing complexity to obtain shortcoming with this plated film bag, and production cost is higher.
And existing infusion bag by 121 degree sterilizing, but transport, in use, outer layer has bacterium, therefore in desinfection chamber not
It can use.
Invention content
In view of the deficiencies of the prior art, the technical problems to be solved by the invention are to provide a kind of high-barrier composite bed doctor
With infusion bag and its manufacturing method, the barrier property of material can be further improved.
In order to realize above-mentioned technical purpose, the present invention adopts the following technical scheme that：A kind of high-barrier composite bed medical infusion
Bag, including transfusion bag body, the transfusion bag body includes interior bag layer, middle bag layer and outer bag layer, the middle bag layer and outer bag layer, inner bag
Layer is compatible, and so that outer bag layer be bonded together with interior bag layer, the interior bag layer is polythene material, middle bag layer be polypropylene,
Styrene-ethylene/butylene-styrene block copolymer and dopamine intermingling material, outer bag layer is polypropylene, Carboxylation benzene second
Alkene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blending layer material, the infusion
The interior bag layer inner wall of bag forms transition zone using low temperature magnetic sputtering, and the inner wall plating of the transition zone is equipped with barrier layer, described outer
The outer wall of bag layer is also plated equipped with barrier layer, and the outer wall of the barrier layer of the outer bag layer forms stenlizing layer using low temperature magnetic sputtering.
Further, the material of the barrier layer is silica, and the material of the stenlizing layer and transition zone is all nanometer
Titanium dioxide.
Further, the stenlizing layer is nano-titanium dioxide and the blending layer material of polyurethanes.
Further, the dopamine weight percent of the middle bag layer is 5-95%.
Further, the silica weight percentage is 75-85%.
A kind of manufacturing method of high-barrier composite bed medical infusion bags, includes the following steps：
1)：It is embedding that the polythene material of interior bag layer, the polypropylene of middle bag layer, styrene-ethylene/butylene-styrene will be made
Section copolymer and the polypropylene of dopamine intermingling material and outer bag layer, carboxylated styrene-ethylene/butylene-styrene block are common
Polymers and the material of nano composite material of anionic polymerization nylon blended layer are purified and are prepared by formula respectively, later
It is stirred respectively；
2)：Injection mold is preheated, the material of three bag layers that step 1 preparation mixes is heated into melting respectively,
Temperature is 250~280 DEG C, and the thick liquid material of three bag layer materials after melting is injected by three die heads in mold respectively
The bag embryo of interior bag layer, middle bag layer and outer bag layer is molded into, and be previously formed three layers of bag embryo is placed and is cooled and shaped；
3)：Nano-titanium dioxide mistake is formed using low temperature magnetic sputtering to the interior bag layer bag embryo inner wall that step 2 is cooled and shaped
Layer is crossed, then sets silica barrier layer to the plating of the inner wall of transition zone；
4)：Silica barrier layer is set to the outer bag layer outer wall plating that step 2 is cooled and shaped, backward silica barrier layer
Outer wall forms nano-titanium dioxide outer wall stenlizing layer using low temperature magnetic sputtering；
5)：Step 3 and 4 three layers of the bag embryos formed are sent into air feeder and blow bag, air blowing air pressure for 1.5~
Three layers required of infusion bag is made in 1.8MPa, blow molding；
6)：By three layers made from step 4 of infusion bag liquid drug；
7)：The infusion bag that liquid drug finishes is sealed.
The present invention technical characterstic and effect be：The present invention is using the nanometer titanium dioxide layer formed by low temperature magnetic sputtering
With antibacterial functions, and also to have the function of that transparent, absorption ultraviolet light is protected from light etc. multi-functional for the stenlizing layer generated, improves drug
Safety；
The dopamine of bag layer, which has, in the present invention eliminates through oxygen, bonding, barriers function, further improves the barrier of material
Performance；
The interior bag layer inner wall of the present invention is using first sputtering nanometer titanium dioxide ti interlayer, rear applying silicon oxide coating, to hinder
Only the additive of polymeric membrane is moved in drug, serving high barrier.Therefore this product has glass high security, height
The advantages of barrier property, it may have soft bag is from the advantages of emptying.The shortcomings that there is the two, overcome the two, while outer bag
Layer uses first applying silicon oxide coating, rear to sputter nanometer titanium dioxide ti interlayer, therefore is protected from light with transparent, absorption ultraviolet light
Function etc. is multi-functional, and the bactericidal effect for improving stenlizing layer, while also carries out the effect of second protection barrier.
Description of the drawings
Fig. 1 is the cross-sectional view of the present invention；
Fig. 2 is the positive structure schematic of the present invention.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to the accompanying drawings and embodiments, it is right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
Embodiment 1
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 is compatible with outer bag layer 4, interior bag layer 2, so as to which outer bag layer 4 and interior bag layer 2 are bonded together, inner bag
Layer 2 is polythene material, and middle bag layer 3 is being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixed material, and the weight percent of dopamine is 5%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blending layer material, 2 inner wall of interior bag layer of infusion bag is using low
Warm magnetron sputtering forms transition zone 5, and the inner wall plating of transition zone 5 is equipped with barrier layer 6, and the outer wall of outer bag layer 4 is also plated equipped with barrier layer
6, the outer wall of the barrier layer 6 of outer bag layer 4 forms stenlizing layer 7 using low temperature magnetic sputtering, and the material of barrier layer 6 is silica,
The material of stenlizing layer 7 and transition zone 5 is all nano-titanium dioxide.
And the process of the said goods includes the following steps：
First, the polythene material of interior bag layer 2 will be made, middle bag layer 3 is polypropylene, styrene-ethylene/butylene-benzene second
The intermingling material of alkene block copolymer and dopamine, and the weight percent of dopamine is 5% and polypropylene, the carboxylic of outer bag layer 4
It is acidified the material of styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer
It is purified and is prepared by formula respectively, is stirred respectively later；
Secondly, injection mold is preheated, the material of three bag layers that step 1 preparation mixes is heated respectively molten
Melt, temperature is 250~280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
The bag embryo of interior bag layer 2, middle bag layer 3 and outer bag layer 4 is molded into tool, and be previously formed three layers of bag embryo placement is cooled to
Type；
Again, nano-titanium dioxide is formed using low temperature magnetic sputtering to 2 bags of embryo inner walls of interior bag layer that step 2 is cooled and shaped
Then transition zone 5 sets silica barrier layer 6 to the plating of the inner wall of transition zone 5；
Again, silica barrier layer 6, backward silica barrier are set to 4 outer wall of the outer bag layer plating that step 2 is cooled and shaped
The outer wall of layer 6 forms nano-titanium dioxide outer wall stenlizing layer 7 using low temperature magnetic sputtering；
Again, step 3 and 4 three layers of the bag embryos formed are sent into air feeder and blow bag, air blowing air pressure for 1.5~
Three layers required of infusion bag is made in 1.8MPa, blow molding；
Again, by three layers made from step 4 of infusion bag liquid drug；
Finally, the infusion bag that liquid drug finishes is sealed.
Embodiment 2
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 is compatible with outer bag layer 4, interior bag layer 2, so as to which outer bag layer 4 and interior bag layer 2 are bonded together, inner bag
Layer 2 is polythene material, and middle bag layer 3 is being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixed material, and the weight percent of dopamine is 95%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blending layer material, 2 inner wall of interior bag layer of infusion bag is using low
Warm magnetron sputtering forms transition zone 5, and the inner wall plating of transition zone 5 is equipped with barrier layer 6, and the outer wall of outer bag layer 4 is also plated equipped with barrier layer
6, the outer wall of the barrier layer 6 of outer bag layer 4 forms stenlizing layer 7 using low temperature magnetic sputtering, and the material of barrier layer 6 is silica,
Stenlizing layer is nano-titanium dioxide and the blending layer material of polyurethanes, and silica weight percentage is 75-85%.
And the process of the said goods includes the following steps：
First, the polythene material of interior bag layer 2 will be made, middle bag layer 3 is polypropylene, styrene-ethylene/butylene-benzene second
The intermingling material of alkene block copolymer and dopamine, and the weight percent of dopamine is 95% and polypropylene, the carboxylic of outer bag layer 4
It is acidified the material of styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer
It is purified and is prepared by formula respectively, is stirred respectively later；
Secondly, injection mold is preheated, the material of three bag layers that step 1 preparation mixes is heated respectively molten
Melt, temperature is 250~280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
The bag embryo of interior bag layer 2, middle bag layer 3 and outer bag layer 4 is molded into tool, and be previously formed three layers of bag embryo placement is cooled to
Type；
Again, nano-titanium dioxide is formed using low temperature magnetic sputtering to 2 bags of embryo inner walls of interior bag layer that step 2 is cooled and shaped
Then transition zone 5 sets silica barrier layer 6 to the plating of the inner wall of transition zone 5；
Again, silica barrier layer 6, backward silica barrier are set to 4 outer wall of the outer bag layer plating that step 2 is cooled and shaped
The outer wall of layer 6 forms the blended layer material walls stenlizing layer 7 of nano-titanium dioxide and polyurethanes using low temperature magnetic sputtering；
Again, step 3 and 4 three layers of the bag embryos formed are sent into air feeder and blow bag, air blowing air pressure for 1.5~
Three layers required of infusion bag is made in 1.8MPa, blow molding；
Again, by three layers made from step 4 of infusion bag liquid drug；
Finally, the infusion bag that liquid drug finishes is sealed.
Embodiment 3
A kind of high-barrier composite bed medical infusion bags, including transfusion bag body 1, transfusion bag body 1 includes interior bag layer 2, middle bag layer 3
With outer bag layer 4, middle bag layer 3 is compatible with outer bag layer 4, interior bag layer 2, so as to which outer bag layer 4 and interior bag layer 2 are bonded together, inner bag
Layer 2 is polythene material, and middle bag layer 3 is being total to for polypropylene, styrene-ethylene/butylene-styrene block copolymer and dopamine
Mixed material, and the weight percent of dopamine is 55%, outer bag layer 4 is polypropylene, carboxylated styrene-ethylene/butylene-benzene second
Alkene block copolymer and nano composite material of anionic polymerization nylon blending layer material, 2 inner wall of interior bag layer of infusion bag is using low
Warm magnetron sputtering forms transition zone 5, and the inner wall plating of transition zone 5 is equipped with barrier layer 6, and the outer wall of outer bag layer 4 is also plated equipped with barrier layer
6, the outer wall of the barrier layer 6 of outer bag layer 4 forms stenlizing layer 7 using low temperature magnetic sputtering, and the material of barrier layer 6 is silica,
Stenlizing layer is nano-titanium dioxide and the blending layer material of polyurethanes, and silica weight percentage is 75-85%.
And the process of the said goods includes the following steps：
First, the polythene material of interior bag layer 2 will be made, middle bag layer 3 is polypropylene, styrene-ethylene/butylene-benzene second
The intermingling material of alkene block copolymer and dopamine, and the weight percent of dopamine is 55% and polypropylene, the carboxylic of outer bag layer 4
It is acidified the material of styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer
It is purified and is prepared by formula respectively, is stirred respectively later；
Secondly, injection mold is preheated, the material of three bag layers that step 1 preparation mixes is heated respectively molten
Melt, temperature is 250~280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into mould by three die heads respectively
The bag embryo of interior bag layer 2, middle bag layer 3 and outer bag layer 4 is molded into tool, and be previously formed three layers of bag embryo placement is cooled to
Type；
Again, nano-titanium dioxide is formed using low temperature magnetic sputtering to 2 bags of embryo inner walls of interior bag layer that step 2 is cooled and shaped
Then transition zone 5 sets silica barrier layer 6 to the plating of the inner wall of transition zone 5；
Again, silica barrier layer 6, backward silica barrier are set to 4 outer wall of the outer bag layer plating that step 2 is cooled and shaped
The outer wall of layer 6 forms the blended layer material walls stenlizing layer 7 of nano-titanium dioxide and polyurethanes using low temperature magnetic sputtering；
Again, step 3 and 4 three layers of the bag embryos formed are sent into air feeder and blow bag, air blowing air pressure for 1.5~
Three layers required of infusion bag is made in 1.8MPa, blow molding；
Again, by three layers made from step 4 of infusion bag liquid drug；
Finally, the infusion bag that liquid drug finishes is sealed.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (6)
1. a kind of high-barrier composite bed medical infusion bags, including transfusion bag body (1), the transfusion bag body (1) is including interior bag layer
(2), middle bag layer (3) and outer bag layer (4), the middle bag layer (3) is compatible with outer bag layer (4), interior bag layer (2), thus by outer bag layer
(4) be bonded together with interior bag layer (2), the interior bag layer (2) be polythene material, middle bag layer (3) for polypropylene, styrene-
The intermingling material of ethylene/butylene-styrene block copolymer and dopamine, outer bag layer (4) for polypropylene, carboxylated styrene-
Ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blending layer material, it is characterised in that：
Interior bag layer (2) inner wall of the infusion bag forms transition zone (5), the inner wall plating of the transition zone (5) using low temperature magnetic sputtering
Equipped with barrier layer (6), the outer wall of the outer bag layer (4) is also plated equipped with barrier layer (6), the barrier layer (6) of the outer bag layer (4)
Outer wall forms stenlizing layer (7) using low temperature magnetic sputtering.
2. high-barrier composite bed medical infusion bags according to claim 1, it is characterised in that：The material of the barrier layer (6)
Matter is silica, and the material of the stenlizing layer (7) and transition zone (5) is all nano-titanium dioxide.
3. high-barrier composite bed medical infusion bags according to claim 1, it is characterised in that：The middle bag layer (3) it is more
Bar amine weight percent is 5-95%.
4. high-barrier composite bed medical infusion bags according to claim 1, it is characterised in that：The stenlizing layer is nanometer two
The blending layer material of titanium oxide and polyurethanes.
5. high-barrier composite bed medical infusion bags according to claim 2, it is characterised in that：The silica weight hundred
Divide than being 75-85%.
6. high-barrier composite bed medical infusion bags according to claim 1, it is characterised in that：Including following production stage：
1)：The polythene material, the polypropylene of middle bag layer (3), styrene-ethylene/butylene-styrene of interior bag layer (2) will be made
The polypropylene of block copolymer and dopamine intermingling material and outer bag layer (4), carboxylated styrene-ethylene/butylene-styrene are embedding
Section copolymer and the material of nano composite material of anionic polymerization nylon blended layer are purified and are prepared by formula respectively,
It is stirred respectively later；
2)：Injection mold is preheated, the material of three bag layers that step 1 preparation mixes is heated into melting, temperature respectively
It is 250~280 DEG C, the thick liquid material of three bag layer materials after melting is injected by three die heads in mold respectively and is molded
Into the bag embryo of interior bag layer (2), middle bag layer (3) and outer bag layer (4), and be previously formed three layers of bag embryo is placed and is cooled and shaped；
3)：Nano-titanium dioxide transition is formed using low temperature magnetic sputtering to interior bag layer (2) bag embryo inner wall that step 2 is cooled and shaped
Layer (5) then sets silica barrier layer (6) to the plating of the inner wall of transition zone (5)；
4)：Silica barrier layer (6), backward silica barrier layer are set to outer bag layer (4) outer wall plating that step 2 is cooled and shaped
(6) outer wall forms nano-titanium dioxide outer wall stenlizing layer (7) using low temperature magnetic sputtering；
5)：Step 3 and 4 three layers of the bag embryos formed to be sent into air feeder and carry out blowing bag, air blowing air pressure is 1.5~1.8MPa,
Three layers required of infusion bag is made in blow molding；
6)：By three layers made from step 4 of infusion bag liquid drug；
7)：The infusion bag that liquid drug finishes is sealed.
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| CN201610317554.3A CN106042548B (en) | 2016-05-13 | 2016-05-13 | A kind of high-barrier composite bed medical infusion bags |
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| CN201610317554.3A CN106042548B (en) | 2016-05-13 | 2016-05-13 | A kind of high-barrier composite bed medical infusion bags |
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| CN106042548B true CN106042548B (en) | 2018-06-19 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106667768A (en) * | 2016-12-30 | 2017-05-17 | 湖南金健药业有限责任公司 | Light-avoiding antibacterial infusion bag and preparation method thereof |
| CN110497671B (en) * | 2019-08-06 | 2021-05-11 | 安徽天润医用新材料有限公司 | High-barrier composite layer medical infusion bag and production method thereof |
| CN110743061A (en) * | 2019-10-10 | 2020-02-04 | 雷诺丽特朗活医药耗材（北京）有限公司 | Infusion bag and portable infusion bag |
| CN118024526A (en) * | 2024-04-15 | 2024-05-14 | 山东齐鲁乙烯化工股份有限公司 | Preparation method of sterilizing outer cover film of medicine bag |
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| CN1919700A (en) * | 2006-03-31 | 2007-02-28 | 上海武杉包装制品有限公司 | Powder and liquid bag and preparation method thereof |
| CN103893012A (en) * | 2014-03-25 | 2014-07-02 | 安徽双鹤药业有限责任公司 | Three-layer medical infusion bag and manufacturing method thereof |
| CN104339654A (en) * | 2013-08-01 | 2015-02-11 | 曹正尚 | Method for manufacturing composite component |
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| EP1474291A4 (en) * | 2002-02-13 | 2010-05-26 | Rf & Son Inc | Novel laminates for producing high strength porous sterilizable packaging |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1919700A (en) * | 2006-03-31 | 2007-02-28 | 上海武杉包装制品有限公司 | Powder and liquid bag and preparation method thereof |
| CN104339654A (en) * | 2013-08-01 | 2015-02-11 | 曹正尚 | Method for manufacturing composite component |
| CN103893012A (en) * | 2014-03-25 | 2014-07-02 | 安徽双鹤药业有限责任公司 | Three-layer medical infusion bag and manufacturing method thereof |
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