CN1919700A - Powder and liquid bag and preparation method thereof - Google Patents
Powder and liquid bag and preparation method thereof Download PDFInfo
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- CN1919700A CN1919700A CN 200610025345 CN200610025345A CN1919700A CN 1919700 A CN1919700 A CN 1919700A CN 200610025345 CN200610025345 CN 200610025345 CN 200610025345 A CN200610025345 A CN 200610025345A CN 1919700 A CN1919700 A CN 1919700A
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Abstract
The invention discloses a powder-liquid container and manufacturing method, which is composed of sealed bag with two bag film on the periphery, wherein the bag possesses at least one powder chamber with antibiotics and liquid chamber with aseptic solution, which is separated by separating part, the separating part is connected by bag film through strippable welding structure, two external sides of bag film of powder chamber possesses a layer of baffle film.
Description
Technical field:
The present invention relates to packing technique, relate in particular to medical airtight container, particularly the infusion preparation airtight container specifically is a kind of Powder and liquid bag and production method thereof.
Background technology:
In the pharmaceuticals industry, often multiple medicine need be mixed the back and in biosome, discharge.The married operation of medicine requires to carry out under germ-free condition.Microbiotic particularly, the injection as hospital uses is stored in aseptic drying regime, need be with the aseptic lysate dissolving of normal saline or glucose during use.In the prior art, the mixed dissolution of microbiotic and lysate need be at aseptic in-house operation, and between cillin bottle, carry out repeatedly, and, can produce a large amount of microbiotic cillin bottles and Biohazard Waste such as normal saline and syringe after the use therefore, proposed powder liquid bag in the prior art, powder liquid bag can be stored in microbiotic and lysate in the same container.The inner layer material that powder liquid bag adopts all is melanges of polypropylene/PE, can under the condition of 105～115 degrees centigrade of sterilising temps, carry out low temperature sterilization, the intermembranous space of leaving of membraneous material and gas barrier, add desiccant therebetween and prevent that oxidizer is beneficial to the single-piece Packing Fee height of this method of long preservation, less economical.The job operation that Japan's patent proposes for No. 3419139 is that the single chamber of making transfusion earlier bag is made antibiotic single chamber bag more separately, then, adopts melting adhered job operation in isolated area.This job operation is very complicated, and two bag welding back weld zones easily produce leakage, and this technology also needs huge equipment investment in addition, and the shortcoming of unstable product quality is arranged.
Summary of the invention:
The purpose of this invention is to provide a kind of Powder and liquid bag, two single chamber bags that described this Powder and liquid bag will solve powder liquid bag in the prior art easily produce leakage, processing technology complicated technology problem at connecting bridge.
A kind of Powder and liquid bag of the present invention is made of a sealing bag, described sealing bag is connected and composed at periphery by two bag films, wherein, at least be provided with a powder chamber and a liquor chamber in the described bag, all isolated between powder chamber that any one described powder chamber is adjacent with any one or the liquor chamber by separating part, described separating part is connected and composed by peelable rosin joint structure by described two bag films, at least be provided with a separating part in the described bag, the described bag of a slice film all is made of thin film at least arbitrarily, and two lateral surfaces of the bag film of described powder chamber are provided with one deck Obstruct membrane.
Further, the described bag of a slice film constitutes by three-layer thin-film arbitrarily.
Further, be provided with two powder chamber and a liquor chamber in the described bag, isolated between described two powder chamber by one first separating part, isolated by one second separating part between at least one powder chamber and the liquor chamber, described first separating part and second separating part connect and compose by peelable rosin joint structure by described two bag films.
Further, an end of described bag is set with a mouth pipe, and described mouthful of pipe is communicated with described powder chamber or liquor chamber, and sealing is provided with a cock body in the described mouthful of pipe, and the outer setting of described cock body has sealing arrangement.
Further, described sealing arrangement is pull-tab structure or bacteria-proof film structure.
Further, described Obstruct membrane is made of composite aluminium film.
Further, have at least in the film of innermost layer in the medial surface to be provided with the striated jut, the height of described striated jut is 5%～15% bag film thickness.
Further, the thickness of described bag film is 180-220 μ m, and the height of described striated jut is 18-22 μ m.
Further, the Obstruct membrane of a bag film lateral surface setting is captiveed joint with described bag film, and the Obstruct membrane that another bag film lateral surface is provided with is connected with described bag film rosin joint.
Further, an end relative with described mouth pipe is provided with a hanging hole, the monosymmetric knock hole that is provided with of described hanging hole on the bag.
Further, the film of bag innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
Further, in the film of bag innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
Further, the outermost film of bag is formed by polypropylene-based resin composition and polyacrylic random vinyl chloride or with polyethylene.
Further, described Obstruct membrane is transparent silica steam plating film, or serves as the multilayer Obstruct membrane of main formation with ethylene-vinyl alkoxide polymer/nylon.
The present invention also aims to provide a kind of method of producing above-mentioned Powder and liquid bag of making, described method comprises the steps: at least
First step is made the bag film, and described bag film is constituted bag,
Second step, on Bag Making Machine, the bag film is printed, then described bag is carried out rosin joint, in the rosin joint process, in bag, constitute two cavitys at least, secondly, both sides, the top of soft bag are sealed at an end soldering opening pipe of bag, cooling is at last sealed and two side portion of bag film is cut edge, sealed
Third step, filling liquid from the mouth pipe is inserted cock body in the inlet pipe then, and at the outside weldings lid of cock body, described bag is sterilized, and cool off and drying,
The 4th step cuts a side of powder chamber, utilizes shedding motion to carry out opening then, the can microbiotic, and the bottom to bag behind the can microbiotic seals,
The 5th step, the tow sides welding Obstruct membrane of the bag behind the can microbiotic, cutting edge then punches out lifting hole(eyelet).
Further, described shedding motion is vacuum cup or other mechanical openings devices.
Further, described mouthful of pipe is ship type mouth pipe or circular port pipe.
Further, described lid is pop can type lid or fungi-proofing membranous type lid.
Further, described Obstruct membrane is the aluminium film, and the aluminium film of at least one side surface of bag is the aluminium film of peelable structure, and the aluminium film and the bag of peelable structure bond by tack coat.
Further, the internal layer at described aluminium film is provided with tack coat.
Further, the aluminium film in bag front is the peel-able film of polyethylene terephthalate/aluminium film/polypropylene-polyethylene class compound, or the peel-able film of polyethylene terephthalate/aluminium film/nylon/polypropylene-polyethylene class compound, the aluminium film of bag reverse side is polyethylene terephthalate/aluminium film/polypropylene film or polyethylene terephthalate/aluminium film/nylon/polypropylene film.
Further, the mode that adopts four side welds to connect is welded the aluminium film.
Further, in the welding of aluminum membrane process, between aluminium film and bag surface, carry out deoxidation treatment, perhaps between aluminium film and bag surface, adopt unreactable gas to replace.
Further, described bag film is made of double-layer films at least, and outermost film is made of the resin combination that propylene random copolymer resin or Propenes resin composition and propylene random copolymer resin constitute.
Further, the film of bag innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
Further, in the film of bag innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
Further, described bag film is made of internal layer membrane, intermediate layer film and outer membrane, the ratio of the thickness of internal layer membrane, intermediate layer film and outer membrane is 1: 3: 1, gross thickness is 190-210 μ m, extruding with inflation film manufacturing machine in the process of bag film, into medical filtrated air is filled in bag film inside, and at the concavo-convex striped of the inboard formation of bag film, the bag film behind the inflation is handled sharply cooling through water-cooled.
Further, described intermediate layer film is made of the resin combination that Propenes resin composition and styrenic elastomer constitute.
Further, the protection face of described Obstruct membrane is greater than or equal to the surface of powder chamber.
Further, after described the 4th step, paste the composite aluminium film of thickness greater than 20 μ at the tow sides of powder chamber.
Further, when producing soft bag, be processed to form striped, form concavo-convex structure in that film is inner at least one side of innermost layer film.
Further, the height of described striped is the 8-12% of bag thickness.
Further, described Obstruct membrane is the multilayer Obstruct membrane of silica steam plating film or ethylene-vinyl alkoxide polymer/nylon etc.
The principle of work of Powder and liquid bag of the present invention is: the sealing of powders such as the microbiotic under the aseptic freeze-dried state, Chinese medicine is kept in the powder chamber, it is indoor that the aseptic lysate sealing of normal saline or glucose is kept at liquor, during use, extruding liquor chamber, the indoor pressure of liquor is broken through the peelable rosin joint structure of separating part, and microbiotic and lysate are finished mixed dissolution in moment.Striated jut in the medial surface of bag film can prevent that film sticks together in the disinfecting action process in bag processing.The bag film can separate with Obstruct membrane, and the bag film is transparent, is convenient to can carry out visual inspection when hospital uses.
The present invention compared with the prior art, its effect is actively and significantly.The present invention is provided with lysate and antibiotic composition simultaneously in a soft bag, during use, if with the partitioned portion in the soft bag from, just can realize the mixing of microbiotic and lysate, avoided repeatedly dissolving operation, be easy to generate the problem of bacterial infection at cillin bottle and saline bottle.Simultaneously owing in the innermost layer bag film of soft bag, when single polypropylene polymerization, added elastomeric material, particle diameter is that the rubber grain of 1～0.2 μ m evenly disperses, present island structure, make that the soft bag transparency is high, the fall strength of briquette height of infusion bag during the good low temperature of rosin joint.Production method of the present invention is all more economical than former any job operation, and productive costs is low, can alleviate national medicine valency burden.
Description of drawings:
Fig. 1 is the structural representation of Powder and liquid bag of the present invention.
Fig. 2 is the scheme drawing of Powder and liquid bag when being in the stored collapsed state of invention.
Fig. 3 is another preferred construction scheme drawing of the Powder and liquid bag of invention.
Fig. 4 be the invention another preferred Powder and liquid bag be in the stored collapsed state time scheme drawing.
The specific embodiment:
As Fig. 1, Fig. 2, Fig. 3 and shown in Figure 4, Powder and liquid bag of the present invention, constitute by a sealing bag 1, described sealing bag 1 is connected and composed at periphery by two bag films, at least be provided with a powder chamber 2 and a liquor chamber 3 in the described bag 1, all isolated between powder chamber 2 that any one described powder chamber 2 is adjacent with any one or the liquor chamber 3 by separating part 4, described separating part 4 is connected and composed by peelable rosin joint structure by described two bag films, at least be provided with a separating part 4 in the described bag 1, the described bag of a slice film all is made of thin film at least arbitrarily, and two lateral surfaces of the bag film of described powder chamber are provided with one deck Obstruct membrane.
Further, the described bag of a slice film is made of three-layer thin-film arbitrarily.
Further, be provided with two powder chamber 2 and a liquor chamber 3 in the described bag 1, described two powder chamber 2 are isolated by one first separating part, isolated by one second separating part between at least one powder chamber 2 and the liquor chamber 3, described first separating part and second separating part connect and compose by peelable rosin joint structure by described two bag films.
Further, an end of described bag 1 is set with a mouth pipe 5, and described mouthful of pipe 5 is communicated with described powder chamber 2 or liquor chamber 3, and sealing is provided with a cock body 6 in the described mouthful of pipe 5, and the outer setting of described cock body 6 has sealing arrangement.
Further, described sealing arrangement is pull-tab structure or bacteria-proof film structure.
Further, described Obstruct membrane is made of composite aluminium film.
Further, have at least in the innermost layer film in the medial surface to be provided with the striated jut, the height of described striated jut is 5%～15% bag film thickness.
Further, the thickness of described bag film is 180-220 μ m, and the height of described striated jut is 18-22 μ m.
Further, the Obstruct membrane of a bag film lateral surface setting is captiveed joint with described bag film, and the Obstruct membrane that another bag film lateral surface is provided with is connected with described bag film rosin joint.
Further, be provided with a hanging hole 7, the monosymmetric knock hole 8 that is provided with of described hanging hole 7 at a end with described mouthful of pipe 5 relative bags 1.
In a preferred embodiment of the invention, the film of bag 1 innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
Further, in the film of bag 1 innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
Further, bag 1 outermost film is formed by polypropylene-based resin composition and polyacrylic random vinyl chloride or with polyethylene.
Further, described Obstruct membrane is transparent silica steam plating film, or serves as the multilayer Obstruct membrane of main formation with ethylene-vinyl alkoxide polymer/nylon.
Manufacturing of the present invention is produced among the embodiment of method of above-mentioned Powder and liquid bag, comprises the steps:
First step is made the bag film, and described bag film is constituted bag 1,
Second step, bag film to wide cut on Bag Making Machine prints, then described bag 1 is carried out rosin joint, in the rosin joint process, in bag 1, constitute two cavitys at least, secondly, both sides, the top of soft bag are sealed at an end soldering opening pipe 5 of bag 1, cooling is at last sealed and two side portion of bag film is cut edge, sealed
Third step is cut edge to bag 1, and filling liquid from mouth pipe 5 is inserted cock body 6 in the inlet pipe 5 then, and at the outside weldings lid of cock body 6, described bag 1 is sterilized, and cool off and drying,
The 4th step cuts a side of powder chamber, utilizes shedding motion to carry out opening then, and the can microbiotic seals the bottom of bag 1,
The 5th step is at the tow sides welding Obstruct membrane of bag 1, cutting edge then, die-cut lifting hole(eyelet) 7.
Concrete, described shedding motion is vacuum cup or other mechanical openings devices.
Concrete, described mouthful of pipe 5 is ship type mouth pipe or circular port pipe.
Concrete, described lid is easy-to-pull type lid or fungi-proofing membranous type lid.
Concrete, described Obstruct membrane is the aluminium film, and the aluminium film of bag 1 at least one side surface is the aluminium film of peelable structure, and the aluminium film and the bag 1 of peelable structure bond by tack coat.
Obstruct membrane prevents that the pharmaceuticals circulation from when preserving moisture absorption and oxidation taking place, and improve the long preservation performance to pharmaceutical products such as microbiotic.
Following data can prove that the packing of aluminium film is fit to the not antibiotic long preservation of oxytolerant G﹠W branch.
| Project | Test method(s) | Unit | The aluminium film | The transparent bag film | |
| NYBase | PETBase | ||||
| Constitute | PET/AL/PET | The NY/ polypropylene | The PET/ polypropylene | ||
| Combined strength bination | STM-1057B | g/20mm | ＞800 | 800 | 800 |
| Heat seal strength | STM-1057B | kg/20mm | 8～10 | 6 | 5～8 |
| Tensile strength | STM-1057B | kg/20mm | 13～15 | 9 | 7～13 |
| Stretch ratio | STM-1057B | ％ | 80～120 | 90 | 90～110 |
| Tear strength | STM-1030M | g | 55 | - | - |
| Resistance of failure | STM-1029 | kg/cm 2 | 7 | - | - |
| Biock intensity | Vacuum Pack method | ℃ | 137 | 137 | 137 |
| The heat-sealing scope | SealTester | ℃ | 190～250 | 180～220 | 180～220 |
| The oxygen amount of penetrating | Pressure application | cc/m 2·atm 27℃65％24h | 0 | 30 | 47 |
| The aqueous vapor amount of penetrating | JISZ0208 | g/m 2·24h | 0 | 10 | 6 |
Concrete, be provided with tack coat at the internal layer of described aluminium film.
Concrete, the aluminium film in bag 1 front is the peel-able film that is fit to the polyethylene terephthalate/aluminium film/polypropylene-polyethylene class compound of disinfecting action, or the peel-able film of polyethylene terephthalate/aluminium film/nylon/polypropylene-polyethylene class compound, the aluminium film of bag 1 reverse side is polyethylene terephthalate/aluminium film/polypropylene film or polyethylene terephthalate/aluminium film/nylon/polypropylene film.
Concrete, the mode that adopts four side welds to connect is welded the aluminium film.
Concrete, in the welding of aluminum membrane process, between aluminium film and bag 1 surface, carry out deoxidation treatment, perhaps between aluminium film and bag 1 surface, adopt unreactable gas to replace.
Concrete, described bag film is made of double-layer films at least, and outermost film is made of the resin combination that propylene random copolymer resin or Propenes resin composition and propylene random copolymer resin constitute.
Concrete, the film of bag 1 innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
Concrete, in the film of bag 1 innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
Concrete, described bag film is made of internal layer membrane, intermediate layer film and outer membrane, the ratio of the thickness of internal layer membrane, intermediate layer film and outer membrane is 1: 3: 1, gross thickness is 190-210 μ m, extruding with inflation film manufacturing machine in the process of bag film, into medical filtrated air is filled in bag film inside, and at the concavo-convex striped of the inboard formation of bag film, the bag film behind the inflation is handled sharply cooling through water-cooled.
Concrete, described intermediate layer film is made of the resin combination that Propenes resin composition and styrenic elastomer constitute.
Concrete, the protection face of described Obstruct membrane is greater than or equal to the surface of powder chamber.
Concrete, in described third step, paste the composite aluminium film of thickness at the tow sides of powder chamber 2 in advance before the sterilization greater than 20 μ.
Concrete, when producing soft bag, be processed to form striped at least one side of innermost layer film, form concavo-convex structure in that film is inner.
Concrete, the height of described striped is the 8-12% of bag 1 thickness.
Concrete, described Obstruct membrane is the multilayer Obstruct membrane of silica steam plating film or ethylene-vinyl alkoxide polymer/nylon etc.
In a preferred embodiment of the present invention, 3 layers of bag film that are used for making powder liquid bag of the present invention require to have the function that following table is listed:
◎ most important zero important △ time important
| The functional requirement of powder liquid bag | Internal layer | The middle level | Outer | Remarks |
| Medical physics and chemistry is learned test | ◎ | ◎ | ◎ | China's test method(s) adopts shredding type |
| Medical animal experiment | ◎ | ◎ | ◎ | The same |
| The test of inner face corpuscle | ◎ | ◎ | Zero | Mobility test after the sterilization |
| Medical transparent | ◎ | ◎ | ◎ | |
| Medical flexibility | Zero | ◎ | Zero | As transfusion flexible bag, need not outer gas during discharge opeing. |
| Complete weldability | ◎ | Zero | △ | Desirable fusing point: internal layer＜middle level＜skin |
| Rosin joint performance before the sterilization | ◎ | Zero | △ | Rosin joint intensity/welding heat line part 〉=10 ℃. |
| Rosin joint performance after the sterilization | ◎ | Zero | △ | Rosin joint intensity before and after the sterilization is certain, be preferably no change. |
| The anti-drop intensity of low temperature | ◎ | ◎ | Zero | Polypropylene is not low temperature resistant to be fallen.The island structure is important. |
| Mouth pipe weld strength | ◎ | ◎ | △ | Weld fully and prevent that the leakage pin hole is very important. |
| Impressionability | △ | △ | ◎ | During sterilization and hospital do not have printing-ink during with alcohol wipe and come off. |
| The sticking joint defence of empty bag sterilization of dress powder part ends | ◎ | Zero | △ | Can carry out the sterilization of sky bag.It is high that melting point resin is wanted.For the low melting point that prevents resin partly produces sticking connection, bag film inside face is done striped processing. |
| The complete welding performance of aluminium film | ◎ | △ | ◎ | Back side aluminium film and medicine bag need welding fully |
| Aluminium film rosin joint performance | ◎ | △ | ◎ | Surfaces of aluminum film inner face and medicine bag need carry out rosin joint |
| In aluminium film when welding, is to the influence of the rosin joint intensity of medicine bag | ◎ | △ | ◎ | During the welding of aluminium film and medicine bag not the rosin joint to medicine bag exert an influence. |
In order to constitute the bag film of the soft bag of the present invention, be necessary for the resin that 3 kinds of bag films (internal layer middle level skin) in above-mentioned 4 select to have above-mentioned 15 functional items.As the example that resin constitutes, it is constructed as follows shown in the table:
| Example 1 thickness 200 μ | Example 2 thickness 200 μ | |||||
| The bag film constitutes | Internal layer | The middle level | Outer | Internal layer | The middle level | Outer |
| Resin | IMWS001 | RT62a-10 | RT62a-8 | IMWS001 | 1003 | 612 |
| Composition | 1 | 3 | 1 | 1 | 3 | 1 |
| Resin M FR | 2.0 | 2.0 | 2.5 | 2.0 | 3.2 | 1.0 |
| Resin density | 0.89 | 0.9 | 0.9 | 0.89 | 0.895 | 0.89 |
| Melting point resin | 170 | 170 | 175 | 170 | 180 | 190 |
| Crooked elastic rate | 320 | 120 | 580 | 320 | 75 | 550 |
Claims (33)
1. Powder and liquid bag, constitute by a sealing bag, described sealing bag is connected and composed at periphery by two bag films, it is characterized in that: be provided with a powder chamber and a liquor chamber in the described bag at least, all isolated between powder chamber that any one described powder chamber is adjacent with any one or the liquor chamber by separating part, described separating part is connected and composed by peelable rosin joint structure by described two bag films, at least be provided with a separating part in the described bag, the described bag of a slice film all is made of thin film at least arbitrarily, and two lateral surfaces of the bag film of described powder chamber are provided with one deck Obstruct membrane.
2. Powder and liquid bag as claimed in claim 1 is characterized in that: the described bag of a slice film constitutes by three-layer thin-film arbitrarily.
3. Powder and liquid bag as claimed in claim 1, it is characterized in that: be provided with two powder chamber and a liquor chamber in the described bag, isolated between described two powder chamber by one first separating part, isolated by one second separating part between at least one powder chamber and the liquor chamber, described first separating part and second separating part connect and compose by peelable rosin joint structure by described two bag films.
4. Powder and liquid bag as claimed in claim 1, it is characterized in that: an end of described bag is set with a mouth pipe, described mouthful of pipe is communicated with described powder chamber or liquor chamber, and sealing is provided with a cock body in the described mouthful of pipe, and the outer setting of described cock body has sealing arrangement.
5. Powder and liquid bag as claimed in claim 4 is characterized in that: described sealing arrangement is pull-tab structure or bacteria-proof film structure.
6. Powder and liquid bag as claimed in claim 1 is characterized in that: described Obstruct membrane is made of composite aluminium film.
7. Powder and liquid bag as claimed in claim 1 is characterized in that: have at least in the film of innermost layer in the medial surface to be provided with the striated jut, the height of described striated jut is 5%～15% bag film thickness.
8. Powder and liquid bag as claimed in claim 7 is characterized in that: the thickness of described bag film is 180-220 μ m, and the height of described striated jut is 18-22 μ m.
9. Powder and liquid bag as claimed in claim 1 is characterized in that: the Obstruct membrane of a bag film lateral surface setting is captiveed joint with described bag film, and the Obstruct membrane that another bag film lateral surface is provided with is connected with described bag film rosin joint.
10. Powder and liquid bag as claimed in claim 1 is characterized in that: an end relative with described mouth pipe on the bag is provided with a hanging hole, the monosymmetric knock hole that is provided with of described hanging hole.
11. Powder and liquid bag as claimed in claim 1, it is characterized in that: the film of bag innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
12. Powder and liquid bag as claimed in claim 11, it is characterized in that: in the film of bag innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
13. Powder and liquid bag as claimed in claim 1 is characterized in that: the outermost film of bag is formed by polypropylene-based resin composition and polyacrylic random vinyl chloride or with polyethylene.
14. Powder and liquid bag as claimed in claim 1 is characterized in that: described Obstruct membrane is transparent silica steam plating film, or serves as the multilayer Obstruct membrane of main formation with ethylene-vinyl alkoxide polymer/nylon.
15. a method of producing Powder and liquid bag as claimed in claim 1 is characterized in that: described method comprises the steps: at least
First step is made the bag film, and described bag film is constituted bag,
Second step, on Bag Making Machine, the bag film is printed, then described bag is carried out rosin joint, in the rosin joint process, in bag, constitute two cavitys at least, secondly, both sides, the top of soft bag are sealed at an end soldering opening pipe of bag, cooling is at last sealed and two side portion of bag film is cut edge
Third step, filling liquid from the mouth pipe is inserted cock body in the inlet pipe then, and at the outside weldings lid of cock body, described bag is sterilized, and cool off and drying,
The 4th step cuts a side of powder chamber, utilizes shedding motion to carry out opening then, the can microbiotic, and the bottom to bag behind the can microbiotic seals,
The 5th step, the tow sides welding Obstruct membrane of the bag behind the can microbiotic, cutting edge then punches out lifting hole(eyelet).
16. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: described shedding motion is vacuum cup or other mechanical openings devices.
17. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: described mouthful of pipe is ship type mouth pipe or circular port pipe.
18. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: described lid is easy-to-pull type lid or fungi-proofing membranous type lid.
19. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: described Obstruct membrane is the aluminium film, and the aluminium film of at least one side surface of powder chamber's bag is the aluminium film of peelable structure, and the aluminium film and the bag of peelable structure bond by tack coat.
20. the production method of Powder and liquid bag as claimed in claim 19 is characterized in that: the internal layer at described aluminium film is provided with tack coat.
21. the production method of Powder and liquid bag as claimed in claim 19, it is characterized in that: the aluminium film in bag front is the peel-able film of polyethylene terephthalate/aluminium film/polypropylene-polyethylene class compound, or the peel-able film of polyethylene terephthalate/aluminium film/nylon/polypropylene-polyethylene class compound, the aluminium film of bag reverse side is polyethylene terephthalate/aluminium film/polypropylene film or polyethylene terephthalate/aluminium film/nylon/polypropylene film.
22. the production method of Powder and liquid bag as claimed in claim 19 is characterized in that: the mode that adopts four side welds to connect is welded the aluminium film.
23. the production method of Powder and liquid bag as claimed in claim 19 is characterized in that: in the welding of aluminum membrane process, between aluminium film and bag surface, carry out deoxidation treatment, perhaps between aluminium film and bag surface, adopt unreactable gas to replace.
24. the production method of Powder and liquid bag as claimed in claim 15, it is characterized in that: described bag film is made of double-layer films at least, and outermost film is made of the resin combination that propylene random copolymer resin or Propenes resin composition and propylene random copolymer resin constitute.
25. the production method of Powder and liquid bag as claimed in claim 24, it is characterized in that: the film of bag innermost layer is made of first composition of 10～60 percentage by weights and second composition of 90～40 percentage by weights, described first composition is more than 90% to be the polymer of major component with coefficient with the polypropylene entirely, described second composition is a polypropylene-based resin, described second composition or constitute by polypropylene-based resin composition and phenylethylene elastic body, described second composition or constitute by two or more the polypropylene mixture of fusing point difference more than 10 degree, described second composition or constitute by polyethylene and polyacrylic mixture.
26. the production method of Powder and liquid bag as claimed in claim 25, it is characterized in that: in the film of bag innermost layer, the composition that dissolves in dimethylbenzene account for described first composition add described second composition whole polymer weight 10%～60%, the amount that dissolves in the alpha-olefin beyond the propylene in the composition of dimethylbenzene under the room temperature condition is less than polymeric 20 percentage by weights.
27. the production method of Powder and liquid bag as claimed in claim 15, it is characterized in that: described bag film is made of internal layer membrane, intermediate layer film and outer membrane, the ratio of the thickness of internal layer membrane, intermediate layer film and outer membrane is 1: 3: 1, gross thickness is 190-210 μ m, extruding with inflation film manufacturing machine in the process of bag film, into medical filtrated air is filled in bag film inside, and at the concavo-convex striped of the inboard formation of bag film, the bag film behind the inflation is handled sharply cooling through water-cooled.
28. the production method of Powder and liquid bag as claimed in claim 27 is characterized in that: described intermediate layer film is made of the resin combination that Propenes resin composition and styrenic elastomer constitute.
29. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: the protection face of described Obstruct membrane is greater than or equal to the surface of powder chamber.
30. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: after described the 4th step is finished, paste the composite aluminium film of thickness greater than 20 μ at the tow sides of powder chamber.
31. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: when producing soft bag, be processed to form striped, form concavo-convex structure in that film is inner at least one side of innermost layer film.
32. the production method of Powder and liquid bag as claimed in claim 31 is characterized in that: the height of described striped is the 8-12% of bag thickness.
33. the production method of Powder and liquid bag as claimed in claim 15 is characterized in that: described Obstruct membrane is the multilayer Obstruct membrane of silica steam plating film or ethylene-vinyl alkoxide polymer/nylon etc.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100253458A CN100430304C (en) | 2006-03-31 | 2006-03-31 | Powder and liquid bag and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100253458A CN100430304C (en) | 2006-03-31 | 2006-03-31 | Powder and liquid bag and preparation method thereof |
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| CN1919700A true CN1919700A (en) | 2007-02-28 |
| CN100430304C CN100430304C (en) | 2008-11-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2006100253458A Active CN100430304C (en) | 2006-03-31 | 2006-03-31 | Powder and liquid bag and preparation method thereof |
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| CN (1) | CN100430304C (en) |
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| CN101678070A (en) * | 2007-03-19 | 2010-03-24 | 赫姆孔医疗技术公司 | Be used to make, store and supply equipment and method such as the freeze-dried material of frozen dry blood plasma |
| CN101973071A (en) * | 2010-08-27 | 2011-02-16 | 刘志强 | Preparation assembly of gypsum slurry |
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| CN102240249A (en) * | 2011-06-13 | 2011-11-16 | 湖南科伦制药有限公司 | Aluminum film protection structure for powder cavity of powder-liquid double-cavity transfusion bag |
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Owner name: SHANGHAI WU BIN PACKING PRODUCTS CO., LTD. Free format text: FORMER OWNER: SHANGHAI WUSHAN PACKING PRODUCTS CO., LTD. Effective date: 20070427 |
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