CN103893012A - Three-layer medical infusion bag and manufacturing method thereof - Google Patents
Three-layer medical infusion bag and manufacturing method thereof Download PDFInfo
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Abstract
The invention aims to provide a three-layer medical infusion bag. The three-layer medical infusion bag comprises a flat infusion bag body of a three-layer structure. The three-layer structure comprises an inner bag layer made of polyethylene material, a middle bag layer made of polypropylene and styrene-ethylene/ butylene-styrene segmented copolymer material and an outer bag layer which is a blended layer of polypropylene, carboxylated styrene-ethylene/ butylene-styrene segmented copolymer and anionic polymerization nylon nanocomposite. The barrier performance of the anionic polymerization nylon nanocomposite of the outer bag layer is excellent. Air inlet is not needed in the infusion process and medicine liquid can automatically flow and is completely drained through the design of the thickness and the width of the infusion bag body, and therefore the whole infusion bag is good in safety, barrier property and infusion performance. The invention further provides a manufacturing method of the three-layer medical infusion bag. One-time injection molding and air blowing are conducted through a three-die-head injection molding die, the whole process is simple and advanced, one-time forming is achieved, the method is suitable for production of the infusion bag, and the manufactured infusion bag meets the infusion requirement.
Description
Technical field
The present invention relates to the field of Medical transfusion container, relate in particular to a kind of safer medical infusion bags and manufacture the method for this transfusion bag.
Background technology
At present, Medical transfusion container has plastic bottle, co-extrusion infusion film and blend transfusion bag several types.The content of simply introducing these several infusion vessels below with and weak point:
As lightweight in the plastic bottle that patent No. CN 201759852 U announce, there is the fine compatibility with medicinal liquid, but aspect infusion model, still there is the defect of vial, need air inlet, thereby the possibility that causes antibacterial harmful in bottle and microgranule to increase, therefore the development of plastic bottle is restricted.
The co-extrusion infusion film that and for example patent No. CN 101462389 A announce, is the film of three layers, has good temperature tolerance, excellent clarity, broad heat-sealing temperature scope, the pliability of high and low temperature environment, the good compatibility, but internal layer is polypropylene, skin does not have barrier layer, is to adopt coextrusion process, expensive, production cost is high, and leakage is its fault of construction.
The blend composition transfusion bag that and for example patent No. CN 102397160 A announce, that this transfusion bag bag has is lightweight, cost is low, quality is high, the feature of integrated molding, in use without air inlet, the transfusion of employing atmospheric pressure, but transfusion flexible bag is the bag that only has one deck or two-layer blend composition, have related substance to move to medicinal liquid with medicinal liquid contact layer, its safety and barrier need to be considered.
The applicant's a patent of invention that the patent No. is CN 101411672 B, a kind of medical infusion soft bag and manufacture method thereof and method for shaping are announced, transfusion bag mouth coordinates the polypropylene combination cover with outsourcing, and fusing point and bag material are not quite identical, takes to carve to check its sealing by fusing effect; In transfusion bag raw material, be added with toughened plastics, expensive, safety is low again; Transfusion bag be flat and width with the ratio of thickness be more than or equal to 3 directly affect medicinal liquid from emptying performance; Transfusion bag side is smooth curved surface circular arc, be unfavorable for medicinal liquid from emptying; Transfusion bag body is flexible plastic, and the dies cavity that transfusion bag body is placed on to respective shapes obtains sizing; Draw-ring type polypropylene combination cover, there will be draw ring easily broken, be difficult to pull open, when sterilizing, draw ring place water vapour easily infiltrates, and pollutes; Simultaneously the one-step method of its production technology (note stretch blow, only for bag, do not comprise composite cover) or all comparatively complexity and easy infection foreign bodies of two step method (injection, bag).The patent of invention of another patent No. CN 103519991 A of the applicant, a kind of novel plastic transfusion bag and manufacture method thereof are announced, be a kind of simple in structure, low cost of manufacture, can allow transfusion bag need not add air inlet needle in the time of transfusion, during with non-air admission type transfusion needle transfusion, completely can be from emptying and can blood back, bag shape does not have compared with gross distortion yet and can stablize the transfusion bag of standing; But this transfusion bag is one deck, its composition polypropylene related substance can move to medicinal liquid, its safety, and barrier needs to be considered.
The patent of invention of the applicant's patent No. CN 1415644 A, has announced a kind of nano composite material of anionic polymerization nylon, and its intensity is high, good rigidly, and barrier property is superior, dimensionally stable, and technique is simple, efficiency is high; According to the shortcoming of several infusion vessels of introducing before, the present invention has adopted the material of above-mentioned patent to carry out bag, thereby is to reach high barrier, especially a kind of nano composite material of anionic polymerization nylon, and it mainly takes blocking effect.
Summary of the invention
The invention provides a kind of safe medical transfusion flexible bag and manufacture method thereof, by the transfusion bag of three layers of bag layer structure being set and corresponding production method being provided, improved stability, safety and barrier, solved the problem occurring in background technology.
The object of this invention is to provide a kind of three layers of medical infusion bags, is mainly transfusion bag body, and the width of transfusion bag body is greater than thickness (being flat shape), and transfusion bag body is combined by three-decker, and three layers are respectively inner bag layer, middle bag layer and outer bag layer; Wherein inner bag layer is namely poly material with medicinal liquid contact layer, middle bag layer is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and the layer that outer bag layer namely contacts with the external world is polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material; Bag mouth is arranged at the top at transfusion bag body, and the bottom interposition of transfusion bag body is equipped with the convenient hanged hook hanging; Also be provided with snap lock taut band at transfusion bag body outer peripheral face simultaneously.
Further improve and be: the cervical region of transfusion bag body is flat shoulder shape, can not think circle, and median surface thickness is 0.18 ~ 0.2mm, and neck side thickness is 3/4 of median surface thickness; The thickness of transfusion bag body both sides is 3/4 of median surface thickness, and its width is 0.8 ~ 1.2mm, is conducive to like this from emptying.
Further improve and be: middle bag layer can be compatible with outer bag layer, inner bag layer, thereby outer bag layer and inner bag layer are bonded together, the structure that three-decker just becomes one.
Further improve and be: the polypropylene of described middle bag layer and the mass ratio (50 ~ 90) of styrene-ethylene/butylene-styrene block copolymer: (5 ~ 55).
Further improve and be: the mass ratio of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of described outer bag layer is (50 ~ 90): (3 ~ 10): (7 ~ 40).
Further improve and be: described middle bag layer also can adopt polypropylene and ethylene to add octene block copolymer or polypropylene and ethylene propylene diene rubber, wherein polypropylene: ethylene adds the mass ratio (50 ~ 90) of octene block copolymer: (5 ~ 55), polypropylene: the mass ratio (50 ~ 90) of ethylene propylene diene rubber: (5 ~ 55).
Further improve and be: the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer need adopt bulking agent to make it compatible, and the present invention adopts carboxylic acid styrene-ethylene/butylene-styrene block copolymer as bulking agent.
Further improve and be: the bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer also can adopt carboxylic acid ethylene and octene block copolymer or carboxylic acid ethylene propylene diene rubber.
A manufacture method for three layers of medical infusion bags, comprises the following steps:
Step 1: the material of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer of polythene material, polypropylene and the styrene-ethylene/butylene-styrene block copolymer material of making respectively inner bag layer, middle bag layer and outer bag layer is carried out respectively to purification and prepares according to given formula, and every kind of material is uniformly mixed respectively 10 ~ 12min afterwards;
Step 2: injection mold is carried out to preheating, step 1 is prepared to the material heating and melting respectively of three bag layers that mix, temperature is 250 ~ 280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into the bag embryo that is injection molded into inner bag layer, middle bag layer and outer bag layer in mould by three die heads respectively;
Step 3: the bag embryo of three layers that step 2 is formed is placed cooling forming;
Step 4: the bag embryo of three layers of the cooling formation of step 3 is blown to bag and process, air blowing air pressure is 1.5 ~ 1.8MPa, just can be blow molded into the required transfusion bag of three layers;
Step 5: carry out liquid drug;
Step 6: liquid drug is complete, seals.
Beneficial effect of the present invention: by the inner bag layer of full-closed structure is set, middle bag layer and outer bag layer; With medicinal liquid contact layer be polyethylene, than domestic and international general polypropylene safety, additive-free moving in medicinal liquid; Outer bag layer adopts the nano composite material of anionic polymerization nylon with high-barrier of declaring patent of independent research as barrier layer simultaneously, has greatly improved bag resistance oxygen, block-water performance, has promoted the safety of medicinal liquid; And be provided with the middle bag layer of polypropylene, styrene-ethylene/butylene-styrene block copolymer layer, outer bag layer and inner bag layer are bonded together.The design of the soft transfusion bag of three layers, makes whole transfusion bag security performance better; The process using injection moulding of this transfusion bag, stretches, the technique of air blowing, this process using three die head injection molds carry out Integratively and are injection molded into embryonic type, technique advanced person, and craftsmenship is strong, require highly without complexity as the production of co-extrusion film, overcome the fault of construction of PP TYPE leakage; Bottom at transfusion bag body is provided with hanged hook, makes to infuse convenient; At transfusion bag body surface flexible locking belt setting up and down, snap lock taut band can be loaded onto liquid level light electric transducer, and liquid level light electric transducer and liquid level observation system connect together, and so just can respond at any time the liquid level of transfusion bag, and infusion process makes patient safer; Whole transfusion bag body is flat shape, and such is designed beautifully, and feet is arranged at the bottom of bag, so just can uprightly stand and be convenient in the plane dosing; It is 1:1.0-1:1.7 that the liquid of while bag takes up room with the ratio of reserving dosing space, the cervical region of transfusion bag body is flat shoulder shape, median surface thickness is 0.18 ~ 0.2mm, neck side thickness is 3/4 of median surface thickness, be conducive to like this from emptying and flow velocity is even, the thickness of both sides is 3/4 of median surface thickness, its width is 0.8 ~ 1.2mm, so just, the smaller volume of bag after can making medicinal liquid flow out, it is large that thereby pressure becomes, be conducive to like this from emptying, infusion process can be emptying compared with the gravity flow of constant speed without air inlet medicinal liquid; In sum, transfusion bag appearance looks elegant of the present invention, safety is good, good barrier property, transfusion performance is good, and it is more convenient to use, and is applicable in medical infusion; Transfusion bag manufacturing approach craft advanced person of the present invention, once-forming, is applicable to the production of this transfusion bag.
Brief description of the drawings
Fig. 1 is front view of the present invention.
Fig. 2 is the partial cross section figure that the present invention looks up.
Wherein: 1-transfusion bag body, 2-inner bag layer, bag layer in 3-, 4-outer bag layer, 5-bag mouth, 6-hanged hook, 7-snap lock taut band.
Detailed description of the invention
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, and this embodiment only, for explaining the present invention, does not form limiting the scope of the present invention.
Embodiment mono-:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, is mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, comprises inner bag layer 2, middle bag layer 3 and outer bag layer 4; Described inner bag layer 2 is exactly that the layer that contacts with medicinal liquid is for polythene material, middle bag layer 3 be polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 is exactly that what contact with the external world layer is polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material; There is bag mouth 5 at the crown center of transfusion bag body 1; In the middle of outside the bottom of described transfusion bag body 1, there is hanged hook 6; The flexible locking belt 7 of transfusion bag body 1 outer peripheral face.The cervical region of transfusion bag body is flat shoulder shape, and median surface thickness is 0.18mm, and neck side thickness is 3/4 of median surface thickness; The thickness of transfusion bag body 1 both sides is 3/4 of median surface thickness, and its width is 0.8mm, is conducive to like this from emptying.Middle bag layer 3 and outer bag layer 4, inner bag layer 2 are compatible, and outer bag layer 4 and inner bag layer 2 are bonded together.The polypropylene of middle bag layer 3 and the mass ratio 60:40 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of outer bag layer 4 is 60:5:35.Middle bag layer 3 also can adopt polypropylene and ethylene to add octene block copolymer or polypropylene and ethylene propylene diene rubber, and wherein polypropylene and ethylene add the mass ratio 60:40 of octene block copolymer, the mass ratio 60:40 of polypropylene and ethylene propylene diene rubber.Outer bag layer 4 adopts the bulking agent of carboxylic acid styrene-ethylene/butylene-styrene block copolymer as polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 also can adopt carboxylic acid ethylene and octene block copolymer or carboxylic acid ethylene propylene diene rubber.
Embodiment bis-:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, is mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, comprises inner bag layer 2, middle bag layer 3 and outer bag layer 4; Described inner bag layer 2 is exactly that the layer that contacts with medicinal liquid is for polythene material, middle bag layer 3 be polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 is exactly that what contact with the external world layer is polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material; There is bag mouth 5 at the crown center of transfusion bag body 1; In the middle of outside the bottom of described transfusion bag body 1, there is hanged hook 6; The flexible locking belt 7 of transfusion bag body 1 outer peripheral face.The cervical region of transfusion bag body 1 is flat shoulder shape, can not think circle, and median surface thickness is 0.19mm, and neck side thickness is 3/4 of median surface thickness; The thickness of transfusion bag body both sides is 3/4 of median surface thickness, and its width is 1.0mm, is conducive to like this from emptying.Middle bag layer 3 and outer bag layer 4, inner bag layer 2 are compatible, and outer bag layer 4 and inner bag layer 2 are bonded together.The polypropylene of middle bag layer 3 and the mass ratio 75:25 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of outer bag layer 4 is 75:7:18.Middle bag layer 3 also can adopt polypropylene and ethylene to add octene block copolymer or polypropylene and ethylene propylene diene rubber, and wherein polypropylene and ethylene add the mass ratio 75:25 of octene block copolymer, the mass ratio 75:25 of polypropylene and ethylene propylene diene rubber.Outer bag layer 4 adopts the bulking agent of carboxylic acid styrene-ethylene/butylene-styrene block copolymer as polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 also can adopt carboxylic acid ethylene and octene block copolymer or carboxylic acid ethylene propylene diene rubber.
Embodiment tri-:
As shown in Figure 1, 2, the present embodiment provides a kind of three layers of medical infusion bags, is mainly transfusion bag body 1, and transfusion bag body 1 is flat shape, and transfusion bag body 1 is three-decker, comprises inner bag layer 2, middle bag layer 3 and outer bag layer 4; Described inner bag layer 2 is exactly that the layer that contacts with medicinal liquid is for polythene material, middle bag layer 3 be polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer 4 is exactly that what contact with the external world layer is polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material; There is bag mouth 5 at the crown center of transfusion bag body 1; In the middle of outside the bottom of described transfusion bag body 1, there is hanged hook 6; The flexible locking belt 7 of transfusion bag body 1 outer peripheral face.The cervical region of transfusion bag body is flat shoulder shape,, median surface thickness is 0.20mm, neck side thickness is 3/4 of median surface thickness; The thickness of transfusion bag body 1 both sides is 3/4 of median surface thickness, and its width is 1.20mm, is conducive to like this from emptying.Middle bag layer 3 and outer bag layer 4, inner bag layer 2 are compatible, and outer bag layer 4 and inner bag layer 2 are bonded together.The polypropylene of middle bag layer 3 and the mass ratio 85:15 of styrene-ethylene/butylene-styrene block copolymer.The mass ratio of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of outer bag layer 4 is 85:4:11.Middle bag layer 3 also can adopt polypropylene and ethylene to add octene block copolymer or polypropylene and ethylene propylene diene rubber, and wherein polypropylene and ethylene add the mass ratio 85:15 of octene block copolymer, the mass ratio 85:15 of polypropylene and ethylene propylene diene rubber.Outer bag layer 4 adopts the bulking agent of carboxylic acid styrene-ethylene/butylene-styrene block copolymer as polypropylene/nano composite material of anionic polymerization nylon.The bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer 4 also can adopt carboxylic acid ethylene and octene block copolymer or carboxylic acid ethylene propylene diene rubber.
Embodiment tetra-:
The present embodiment provides a kind of manufacture method of three layers of medical infusion bags, comprises the following steps:
Step 1: the material by making respectively three layers: polythene material, polypropylene and styrene-ethylene/butylene-styrene block copolymer material and polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer are carried out respectively purification and are prepared by the formula of formulating, and are uniformly mixed respectively afterwards 10min;
Step 2: injection mold is carried out to preheating, the material of three bag layers that preparation is uniformly mixed is heating and melting respectively, temperature is 265 DEG C, and the thick liquid material of three bag layer materials after melting is injected into and in mould, is injection molded into the bag embryo that three-decker contains inner bag layer 2, middle bag layer 3 and outer bag layer 4 by three die heads respectively;
Step 3: the bag embryo of three layers that step 2 is formed is placed cooling forming;
Step 4: the bag embryo of three layers of cooling forming is sent in air feeder and blown bag, and air blowing air pressure is 1.6MPa, is blow molded into the required transfusion bag of three layers;
Step 5: press solid-liquid ratio liquid drug;
Step 6: liquid drug is complete, finally seals.
In sum, four embodiment transfusion bag all can reach transfusion requirement.
By the inner bag layer 2 of full-closed structure is set, middle bag layer 3 and outer bag layer 4; With medicinal liquid contact layer be polyethylene, than domestic and international general polypropylene safety, additive-free moving in medicinal liquid; Simultaneously outer bag layer 4 adopts nano composite material of anionic polymerization nylon that independent research has high-barrier as barrier layer, has greatly improved bag resistance oxygen, block-water performance, has promoted the safety of medicinal liquid; And be provided with the middle bag layer 3 of polypropylene, styrene-ethylene/butylene-styrene block copolymer layer, outer bag layer 4 and inner bag layer 2 are bonded together.The design of the soft transfusion bag of three layers, makes whole transfusion bag security performance better; Be provided with hanged hook 6 in the bottom of transfusion bag body, make to infuse convenient; At transfusion bag body surface flexible locking belt 7 setting up and down, snap lock taut band 7 can be loaded onto liquid level light electric transducer, liquid level light electric transducer and liquid level observation system connect together, and so just can respond at any time the liquid level of transfusion bag, and infusion process makes patient safer; Whole transfusion bag body 1 is flat shape, and such is designed beautifully, and feet is arranged at the bottom of bag, so just can uprightly stand and be convenient in the plane dosing; It is 1:1.4 that the liquid of while bag takes up room with the ratio of reserving dosing space, the cervical region of transfusion bag body 1 is flat shoulder shape, neck side thickness is 3/4 of median surface thickness, be conducive to like this from emptying and flow velocity is even, the thickness of both sides is 3/4 of median surface thickness, so just can make the smaller volume of the rear bag of medicinal liquid outflow, large thereby pressure becomes, be conducive to like this from emptying, infusion process can be emptying compared with the gravity flow of constant speed without air inlet medicinal liquid; The process using injection moulding of this transfusion bag, stretch, the technique of blowing, this process using three die head injection molds carry out Integratively and are injection molded into embryonic type, technique advanced person, and craftsmenship is strong, require high without complexity as the production of co-extrusion film, overcome the fault of construction of PP TYPE leakage, and made to such an extent that transfusion bag meets the requirement of transfusion, can more bring into play the performance of material compared with technique before; In sum, transfusion bag appearance looks elegant of the present invention, safety is good, good barrier property, transfusion performance is good, and it is more convenient to use, and is applicable in medical infusion; Transfusion bag manufacturing approach craft advanced person of the present invention, once-forming, is applicable to the production of this transfusion bag.
Claims (10)
1. three layers of medical infusion bags, comprise transfusion bag body (1), it is characterized in that: described transfusion bag body (1) is flat shape, and the width of bag is greater than thickness, transfusion bag body (1) is three-decker, comprises inner bag layer (2), middle bag layer (3) and outer bag layer (4); Described inner bag layer (2) is polythene material, middle bag layer (3) is polypropylene and styrene-ethylene/butylene-styrene block copolymer material, and outer bag layer (4) is polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and nano composite material of anionic polymerization nylon blended layer material; The crown center of described transfusion bag body (1) is provided with bag mouth (5); The bottom of described transfusion bag body (1) is outside equipped with hanged hook (6); Described transfusion bag body (1) outer peripheral face is provided with snap lock taut band (7).
2. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: described middle bag layer (3) and outer bag layer (4), inner bag layer (2) are compatible, thereby outer bag layer (4) and inner bag layer (2) are bonded together.
3. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: the cervical region part of described transfusion bag body (1) is flat shoulder shape, and median surface thickness is 0.18 ~ 0.2mm, and neck side thickness is 3/4 of median surface thickness.
4. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: the thickness of described transfusion bag body (1) both sides is 3/4 of median surface thickness, and its width is 0.8 ~ 1.2mm.
5. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: the described middle bag layer polypropylene of (3) and the mass ratio of styrene-ethylene/butylene-styrene block copolymer (50 ~ 90): (5 ~ 55).
6. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: the mass ratio of polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of described outer bag layer (4) is (50 ~ 90): (3 ~ 10): (7 ~ 40).
7. a kind of three layers of medical infusion bags as claimed in claim 1, it is characterized in that: described middle bag layer (3) also can adopt polypropylene and ethylene to add octene block copolymer or polypropylene and ethylene propylene diene rubber, wherein polypropylene: ethylene adds the mass ratio (50 ~ 90) of octene block copolymer: (5 ~ 55), polypropylene: the mass ratio (50 ~ 90) of ethylene propylene diene rubber: (5 ~ 55).
8. a kind of three layers of medical infusion bags as claimed in claim 1, is characterized in that: described outer bag layer (4) adopts the bulking agent of carboxylic acid styrene-ethylene/butylene-styrene block copolymer as polypropylene/nano composite material of anionic polymerization nylon.
9. a kind of three layers of medical infusion bags as claimed in claim 6, is characterized in that: the bulking agent of the polypropylene/nano composite material of anionic polymerization nylon of described outer bag layer (4) also can adopt carboxylic acid ethylene and octene block copolymer or carboxylic acid ethylene propylene diene rubber.
10. a manufacture method for three layers of medical infusion bags as claimed in claim 1, is characterized in that: comprise the following steps:
Step 1: the material of making the polythene material of inner bag layer (2), the middle bag layer polypropylene of (3) and polypropylene, carboxylic acid styrene-ethylene/butylene-styrene block copolymer and the nano composite material of anionic polymerization nylon blended layer of styrene-ethylene/butylene-styrene block copolymer material and outer bag layer (4) is carried out respectively to purification and prepares by formula, be uniformly mixed respectively afterwards 10 ~ 12min;
Step 2: injection mold is carried out to preheating, step 1 is prepared to the material heating and melting respectively of three bag layers that mix, temperature is 250 ~ 280 DEG C, and the thick liquid material of three bag layer materials after melting is injected into the bag embryo that is injection molded into inner bag layer (2), middle bag layer (3) and outer bag layer (4) in mould by three die heads respectively;
Step 3: the bag embryo of three layers that step 2 is formed is placed cooling forming;
Step 4: the bag embryo of three layers that step 3 is formed is sent in air feeder and blown bag, and air blowing air pressure is 1.5 ~ 1.8MPa, and the required transfusion bag of three layers is made in blow molding;
Step 5: the transfusion bag liquid drug of three layers that step 4 is made;
Step 6: transfusion bag complete liquid drug is sealed.
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Cited By (8)
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| CN104287964A (en) * | 2014-10-09 | 2015-01-21 | 华润双鹤药业股份有限公司 | Double-layer medical infusion bottle and manufacturing method thereof |
| CN106042548A (en) * | 2016-05-13 | 2016-10-26 | 安徽工程大学 | High-barrier composite-layer medical infusion bag |
| CN108058655A (en) * | 2018-01-02 | 2018-05-22 | 温州市环球汽车衬垫有限公司 | A kind of automobile using gusset cavity acoustical cotton and preparation method thereof |
| CN108463203A (en) * | 2016-01-21 | 2018-08-28 | 德国梅尔松根·B·布劳恩股份有限公司 | Medicine bag with integrated flushing option |
| CN110497671A (en) * | 2019-08-06 | 2019-11-26 | 安徽天润医用新材料有限公司 | A kind of high-barrier composite layer medical infusion bags and its production method |
| CN113736173A (en) * | 2021-07-28 | 2021-12-03 | 上海乐纯生物技术有限公司 | Cell therapy liquid storage bag and manufacturing method thereof |
| CN114851672A (en) * | 2022-07-07 | 2022-08-05 | 山东兰德英科新材料科技有限公司 | Method for preparing infusion bag by adopting biodegradable infusion bag special material |
| CN114889280A (en) * | 2022-06-17 | 2022-08-12 | 应城市恒天药业包装有限公司 | Disposable high-barrier film for intravenous nutrition infusion bag and preparation method thereof |
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