CN201492678U - Ampoule of bottle opening cock - Google Patents
Ampoule of bottle opening cock Download PDFInfo
- Publication number
- CN201492678U CN201492678U CN2009202208850U CN200920220885U CN201492678U CN 201492678 U CN201492678 U CN 201492678U CN 2009202208850 U CN2009202208850 U CN 2009202208850U CN 200920220885 U CN200920220885 U CN 200920220885U CN 201492678 U CN201492678 U CN 201492678U
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- bottle
- ampoule
- bottleneck
- plug
- bottle body
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Abstract
The utility model relates to a novel plastic ampoule of a bottle opening cock, belonging to the technical field of medicine packaging. The ampoule consists of a bottle body and a top cap. The upper part of a bottle body forms a conic table, and the upper part of the conic table forms a bottle neck. A T-shaped bottle opening cock is covered in the bottle neck. A bottle opening closing line is formed in the middle of the upper part of the bottle opening cock, and the circular top cap is arranged on the upper part of the closing line. A square opening plate is arranged in the middle of on the upper part of the top cap. Reinforcing ribs are arranged on the two sides of the part between the upper part of the conic table and the top of the closing bottle opening cock. Projected frames are arranged on the two sides of the bottle body surface which is parallel to the opening plate on the lower part of the bottle body. Numbers are arranged on the projected frames, and two projected parts are arranged on the bottom of the bottle body. The bottle body, the opening plate of the top cap and the reinforcing ribs are made from resin materials. The plastic ampoule has the advantages that the chips are prevented from being generated when the ampoule is opened, so the safety of clinic use is improved; the operation in the use process is safe, operating personnel can not be scratched by ampoule chips, and the ampoule is conveniently opened and operated; medicine compatibility is good, and physical liquor stability is ensured.
Description
Technical field
This utility model belongs to the drug packaging technical field, particularly relates to medical novel plastic injection bottleneck tool plug ampoule.
Background technology
The injection ampoule of China pharmaceutical factory production at present is glass ampule, and there are many safety hidden danger in glass ampule.Hidden danger 1: glass ampule need be broken disconnected ampoule off with the fingers and thumb in use, fragility because of glass, make breaking disconnected ampoule off with the fingers and thumb and take a large amount of glass chip simultaneously out of, glass chip is directly entered in the medicine, and it is more than 50 microns that human eye is differentiated microgranule, because of human capillary vessel's diameter only has about 7 microns, a large amount of not visible glass granules are imported human body with medicine, have " invisible particle contamination " harm, and the harm of this microgranule has potentiality and persistency, mainly shows as:
Aseptic inflammation in the region muscle, vein tissue, it is red to show as the part, swollen, bitterly, scleroma, thrombophlebitis.
Enter whole body with blood circulation, microgranule is trapped in the lung, stimulate to cause the huge cell proliferation formation lung internal granuloma of having a liking for, and pulmonary edema, as: cause that the extensive thromboembolism of pulmonary capillary causes ARDS (adult respiratory distress syndrome) and takes place, cause death.
The main pathomechanism of MODS (multiple organ dysfunction syndrome syndrome)/ARDS is a microcirculation disturbance, and microgranule can become thrombosis or the accumulative center of inflammation.
Stop up local tiny blood vessels, cause blood supply insufficiency, histanoxia causes tumor; The particle collision effect causes thrombocytopenia in the blood; A large amount of microgranules stimulate the generation pyrogen, cause the reaction of pyrogen sample.
Hidden danger 2: the glass ampule production technology is when heat-sealing, high temperature melting glass draws envelope, make a bottle interior air swollen the rising that be heated, sealing by fusing cooling back is because expanding with heat and contract with cold of air makes generation negative pressure in the ampoule, when opening glass ampule, moment will suck and suck air when a large amount of air are opened, to cause airborne antibacterial or sneak into attached to the antibacterial on the glass granules, and can pollute transfusion, the human body input can be caused bacteremia and toxic shock by the transfusion of germ contamination on a small quantity.
Hidden danger 3: safe medical protection can not be provided, and the fracture that glass is opened is sharp keen, easily scratches operator, causes antibacterial or disease infection.
Hidden danger 4: because glass ampule sign adopts printing, so spray printing unclear be one of reason of causing the administration mistake.
Hidden danger 5: also can produce big chip when glass fractures, splash on the operating board, pollute operating table surface and environment.
Hidden danger 6: the glass ampule wall is thin frangible, is not easy to transportation and recycling.
Is that the particulate matter that produces detects to glass ampule and plastic ampoule by clinical use, and its measured value sees table 1 for details.
Table 1 glass ampule and plastic ampoule are the particulate matter result who produces by clinical use
Chinese Pharmacopoeia only to infusion solutions regulation pyrogen, control by particulate matter at present, and to small-volume injection, the injectable powder no standard.The particularly clinical operation of getting it filled is at present adopted and is inverted the aspiration medicinal liquid method, cause medicinal liquid contact ampoule fracture, and the incision position glass granules is maximum, in use produces a large amount of microgranules as glass ampule, and is influential to the safety of patient treatment.
China was introduced into Chinese enterprises as transfusion with packaging material with polythene material from Japan's introduction in 1984, the birth of plastic containers has remedied the defective of glass container " easily broken, heaviness ", therefore begun a container revolution in the injection field, China begins to produce the transfusion of plastic containers (plastic bottle).The cover device of plastic bottle is the rubber parcel, and is reliable again with promptly making things convenient for as transfusion.Develop again in succession as the distilled water of injection ampoule and normal saline 10ml, the listing of 20ml container, thereby make plastic containers dress preparation replace the glass ampoule.Make little pin packing the situation of plastic ampoule replacement glass ampule occur.But the top cover of plastic ampoule is inconvenient to open, and is need be further perfect.
Summary of the invention
In order to solve as above problem, the purpose of this utility model provides a kind of novel bottleneck tool plug ampoule, promptly makes things convenient for and opens and safety.
This utility model adopts following technical scheme to achieve the above object: a kind of novel plastic bottleneck tool plug ampoule, it is characterized in that the taper platform is formed at circular bottle 7 tops, bottleneck 5 is formed at taper platform top, add in the bottleneck 5 "T"-shaped bottle plug 5 ', bottle plug 5 ' the middle part, top form bottleneck blockade line 4, blockade line 4 tops are provided with circular top cover 3, the middle part, top of top cover 3 is provided with a long square plate shape and opens plate 2, to the plug both sides, 5 ' crown center position that seal a bottle ribs 6 is set on taper platform top, the bottle face both sides parallel with opening plate 2 in bottle 7 bottoms are provided with protruding frame 8, on the projection frame 8 Arabic numerals are set, in bottle 7 bottoms two lobe 9, bottle 7 are set, top cover 3, open plate 2, ribs 6 is to select for use resin material to make.
Described novel plastic bottleneck tool plug ampoule is characterized in that the straight neck of the straight neck of top cover 3 less than bottle plug 5 ' bottleneck 5, other position wall thickness of the wall ratio of bottleneck blockade line 4, and the length of ribs 6 is identical with the length of opening plate 2.
Described novel plastic bottleneck tool plug ampoule is characterized in that described resin material is polypropylene or polyethylene; Bottle plug 5 ' be to make with rubber.
The advantage of this utility model novel plastic bottleneck tool plug ampoule:
1, the using method of injection ampoule 1 is to adopt aseptic technology, at first prepare bottle 2, top cover 3, the cold-aseptic filling medicinal liquid is no longer sterilized and is avoided the composition of product high temperature sterilize generation to decompose then, after the fill that top cover 3 and bottle 2 heat sealings are integrated, promptly finish the making of injection ampoule 1.System bottle, fill, involution are integrated, and technological process is shortened, and avoid the production environment pollution.
2, the clinical ease of use of plastic ampoule: because the plastic ampoule material is a polyethylene,, therefore can provide safe medical protection, prevent to scratch operator, cause antibacterial or disease infection operator so fracture is not sharp keen.Plastic ampoule adopts the torsion uncork, and rotation gets final product uncork, uses easy to operate.Plastic ampoule sign adopts the colored printing label, clearly easily distinguishes, is convenient to identification, prevents the administration mistake.The plastic ampoule material is solid, and anticollision is difficult for fragmentation, and accumulating is carried and taken care of easily.Be convenient to transport and carry, as be placed in the pocket.
3, the plastic ampoule production technology adopts aseptic technology, and system bottle/fill/involution is integrated, with in the market glass ampule bigger difference is arranged, and sees down plastic ampoule and glass ampule production technology contrast table for details:
| Production technology | The aseptic technology of plastic ampoule | Glass ampule high temperature sterilize production technology |
| Technological process | Adopt aseptic technology, system bottle/fill/involution is integrated, and technological process is short, avoids production environment to pollute | Complex process, long flow path, time production cycle is long, and the production environment opportunities for contamination is big |
| Sterilization ensures | Cold-aseptic filling, no longer the composition decomposition that the product high temperature sterilize produces is avoided in sterilization | High temperature sterilize, produce that effective ingredient decomposes as: glucose produces 5 Hydroxymethylfurfural |
| Process for purifying | Full scale production hundred grades of protections in zone | Only fill hundred grades of protections in zone |
| Water system | Bacterial endotoxin＜0.01EU/ml | No standard |
| Filtration system | Dual sterile filtering device, filter material adopts the disposable use of import U.S.'s bohr aseptic filtration material, does not reuse | Non-sterile filtration, filter material is reused |
| The production system sealing gland | Production system adopts nitrogen protection, avoids the Oxidation of oxygen to medicine | The production system air |
| Compounding system | Before the airtight preparation raw material is adopted aseptic process | Do not require |
The clinical use of plastic ampoule guarantees that patient's life security not only requires the high-quality property of product, and requirement is in the process safety of clinical use, plastic ampoule is because the ductility height of material, can not produce chip, so can overcome the glass ampule shortcoming, have the following advantages: the fragment when avoiding opening produces, and improves the safety of clinical use.
The use handling safety can not scratch operator, and unlatching is used easy to operate, and drug compatibility is good, guarantees that medicinal liquid is stable.
Description of drawings
Fig. 1 is the front view of this utility model plastics spout tool plug ampoule.
Fig. 2 is the left view of this utility model plastics spout tool plug ampoule.
Fig. 3 is the vertical view of this utility model plastics spout tool plug ampoule.
Fig. 4 is the upward view of this utility model plastics spout tool plug ampoule.
Explanation to the drawing symbol:
1: bottleneck tool plug ampoule 2: open plate
3: top cover 4: the bottleneck blockade line
5: bottleneck 5 ': bottle plug
6: ribs 7: bottle
8: protruding frame 9: lobe
The specific embodiment
Below in conjunction with accompanying drawing, describe the embodiment of this utility model plastics spout tool plug ampoule in detail.Fig. 1 is the front view of this utility model plastics spout tool plug ampoule.Fig. 2 is the left view of this utility model plastics spout tool plug ampoule.Fig. 3 is the vertical view of this utility model plastics spout tool plug ampoule.Fig. 4 is the upward view of this utility model plastics spout tool plug ampoule.Shown in Fig. 1～4, bottleneck tool plug ampoule 1 is to select for use resin material (polypropylene or polythene material) to adopt to annotate blow moulding formation, the taper platform is formed at circular bottle 7 tops, bottleneck 5 is formed at taper platform top, add in the bottleneck 5 "T"-shaped bottle plug 5 ', bottle plug 5 ' be to make with rubber, bottle plug 5 ' the middle part, top form bottleneck blockade line 4, blockade line 4 tops are provided with circular top cover 3, the middle part, top of top cover 3 is provided with a long square plate shape and opens plate 2, to the plug both sides, 5 ' crown center position that seal a bottle ribs 6 is set on taper platform top, the bottle face both sides parallel with opening plate 2 in bottle 7 bottoms are provided with protruding frame 8, on the projection frame 8 Arabic numerals are set, two lobe 9, bottle 7 are set in bottle 7 bottoms, top cover 3, open plate 2, ribs 6 is to select for use resin material to make.
The straight neck of circular top cover 3 is less than the straight neck of bottle plug 5 ' bottleneck 5, other position wall thickness of the wall ratio of bottleneck blockade line 4, and the length of ribs 6 is identical with the length of opening plate 2;
The using method of bottleneck tool plug ampoule 1 is to adopt aseptic technology, at first prepare bottle 7, cold-aseptic filling medicinal liquid then, no longer the composition decomposition that the product high temperature sterilize produces is avoided in sterilization, after the fill with after bottle plug 5 ' adding, heat sealing bottle plug 5 ' integrated formation top cover 3 and unlatching plate 2 are promptly finished the making of bottleneck tool plug ampoule.System bottle, fill, involution are integrated, and technological process is shortened, and avoid the production environment pollution.
When medical personnel use bottleneck tool plug ampoule 1, break into two with one's hands to a direction and to open plate 2 and can tear bottleneck blockade line 4, extract liquid in the bottleneck tool plug ampoule 1 with syringe, promptly safety is convenient and swift again.
The technical scheme of injection ampoule 1 is not only applicable to medicine, is equally applicable to the packing as liquid such as beverage, food.
Claims (3)
1. novel plastic bottleneck tool plug ampoule, it is characterized in that the taper platform is formed at circular bottle (7) top, bottleneck (5) is formed at taper platform top, add "T"-shaped bottle plug (5 ') in the bottleneck (5), the middle part, top of bottle plug (5 ') forms bottleneck blockade line (4), blockade line (4) top is provided with circular top cover (3), the middle part, top of top cover (3) is provided with a long square plate shape and opens plate (2), to the both sides, plug (5 ') crown center position that seal a bottle ribs (6) is set on taper platform top, the bottle face both sides parallel with opening plate (2) in bottle (7) bottom are provided with protruding frame (8), on the projection frame (8) Arabic numerals are set, in bottle (7) bottom two lobe (9), bottle (7) are set, top cover (3), open plate (2), ribs (6) is to select for use resin material to make.
2. novel plastic bottleneck tool plug ampoule according to claim 1, it is characterized in that the straight neck of the straight neck of top cover (3) less than bottle plug (5 ') bottleneck (5), other position wall thickness of the wall ratio of bottleneck blockade line (4), the length of ribs (6) is identical with the length of opening plate (2).
3. novel plastic bottleneck tool plug ampoule according to claim 1 is characterized in that described resin material is polypropylene or polyethylene; Bottle plug (5 ') is to make with rubber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202208850U CN201492678U (en) | 2009-09-27 | 2009-09-27 | Ampoule of bottle opening cock |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202208850U CN201492678U (en) | 2009-09-27 | 2009-09-27 | Ampoule of bottle opening cock |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201492678U true CN201492678U (en) | 2010-06-02 |
Family
ID=42435888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009202208850U Expired - Lifetime CN201492678U (en) | 2009-09-27 | 2009-09-27 | Ampoule of bottle opening cock |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201492678U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103458849A (en) * | 2011-04-06 | 2013-12-18 | 株式会社大塚制药工厂 | Plastic ampule |
| CN104739644A (en) * | 2013-12-25 | 2015-07-01 | 楚天科技股份有限公司 | Plastic ampoule bottle |
-
2009
- 2009-09-27 CN CN2009202208850U patent/CN201492678U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103458849A (en) * | 2011-04-06 | 2013-12-18 | 株式会社大塚制药工厂 | Plastic ampule |
| CN104739644A (en) * | 2013-12-25 | 2015-07-01 | 楚天科技股份有限公司 | Plastic ampoule bottle |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20100602 |
|
| CX01 | Expiry of patent term |