CN106029157B - 输送适配器、注射器与导管的适配方法和栓塞剂输送系统 - Google Patents
输送适配器、注射器与导管的适配方法和栓塞剂输送系统 Download PDFInfo
- Publication number
- CN106029157B CN106029157B CN201480076090.0A CN201480076090A CN106029157B CN 106029157 B CN106029157 B CN 106029157B CN 201480076090 A CN201480076090 A CN 201480076090A CN 106029157 B CN106029157 B CN 106029157B
- Authority
- CN
- China
- Prior art keywords
- connector
- adapter
- conduit
- syringe
- pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M2039/0009—Assemblies therefor designed for particular applications, e.g. contrast or saline injection, suction or irrigation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M2039/1077—Adapters, e.g. couplings adapting a connector to one or several other connectors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49716—Converting
Abstract
描述了一种可作为注射器和导管接头之间的接口的输送适配器、注射器与导管的适配方法和栓塞剂输送系统。适配器包括：第一连接器，所述第一连接器适用于连接注射器；第二连接器，所述第二连接器适用于连接导管接头；管，所述管延伸穿过所述第二连接器；桥接片，所述桥接片被设置在所述第一和所述第二连接器之间。
Description
相关申请
本申请要求2013年12月20日提交的申请号为61/913664，名称为液体栓塞剂输送适配器的美国临时专利申请的优先权权益。以上申请的全部内容通过引用被并入本申请中。
技术领域
本发明涉及一种输送适配器、注射器与导管的适配方法和栓塞剂输送系统。
背景技术
输送适配器通常可以用作注射器和导管接头之间的接口。该注射器可以包含液体材料，特别是诸如液体栓塞剂的高粘度材料。液体栓塞剂可以被看做是能够用于填充诸如动脉瘤、动静脉畸形、瘘管或者其他畸形的各种血管畸形的生物相容胶。液体栓塞剂也能够被用于诸如血管闭合、输卵管闭塞或者外周血管的闭合的各种用于闭塞的目的。该输送适配器有助于减少甚至消除在导管中的粘性液体材料的稀释，用于将该粘性液体物质输送到血管内的治疗部位。
发明内容
描述了一种输送适配器。
在一实施例中，输送适配器包括近端连接器、远端连接器、微型管及桥接片。
在另一实施例中，输送适配器包括近端连接器、远端连接器、微型管、桥接片及远端旋转元件。
在另一实施例中，输送粘性液体材料的方法使用所描述的所述输送适配器的方案。
附图说明
图1-2是根据本发明的导管接头的示意图；
图3是根据本发明的一实施例的输送适配器的平面图；
图4是根据本发明的另一实施例的输送适配器的平面图；
图5是图4所示输送适配器的透视图；
图6是根据本发明的又一实施例的输送适配器的平面图；
图7A描述了根据本发明的输送适配器的进一步的实施例；
图7B说明了图7A所示实施例的线状结构的横截面图。
具体实施方式
对于以下描述，在特定的图中使用到的近端以及远端，应当理解通常近端指的是图中位于顶部的项以及远端指的是位于底部的项。所描述的输送适配器的顶端或近端连接注射器，且其底端或远端连接导管接头。当所述输送适配器用于输送时，可以无需采用如大多数图中所示的垂直设置、自上而下的方式(即适配器可以横向设置，从左至右或从右至左取决于输送配置)。
液体栓塞剂通常被从注射器输送至导管，接着从所述导管输送至病人血管内的治疗部位。所述栓塞剂材料流经所述注射器，流入所述导管接头，其中所述接头22包括锥形储液器24，其可引流至更小直径的通道26以及所述接头的其余部分(见图1)。
由于所述锥形储液器24，对于生理盐水或DMSO或是其他液体，在这些液体被用来冲刷所述导管的储液器24和接头22后能够保留在所述储液器中。在液体栓塞剂接下来被输送时，保留的冲刷液体(例如生理盐水或DMSO)可以与所述液体栓塞剂混合，从而稀释了所述液体栓塞剂。适配器提供了一种用于从所述注射器向所述导管输送所述液体栓塞剂的接口，同时最大限度地降低与所述导管接头储液器的接触，从而减少甚至消除冲刷液体对所述液体栓塞剂的任何稀释。
所述适配器包括微型管20，通过该微型管输送所述液体栓塞剂且该微型管位于所述导管接头内。在图1中，所述微型管20位于所述导管储液器24的所述远端，因此最大限度地降低了与保留在所述储液器24中的任何冲刷液体之间潜在的混合。
在图2中，所述微型管20完全绕过了所述储液器且位于所述更小直径的通道26内。所描述的适配器可以根据所述储液器24的尺寸和所述微型管20的长度，采用如图1-2所示的位于所述导管接头22内的任意配置。
图3所示的输送适配器的一个实施例中，包括近端连接器12、远端连接器28、微型管20以及桥接片30，该桥接片位于所述近端和远端连接器12、28之间。所述近端连接器12可以由聚合物构成且可以包括形如旋锁公头的配合部件10，其与注射器的母连接器相连接。所述近端连接器12还可以包括粗糙部件14以帮助使用者抓握所述适配器以便从所述注射器上拧紧或拧下所述适配器。在一示例中，所述微型管20凹进并被捕获在所述近端连接器12的一部分内。在一示例中，所述近端连接器12包括一个通道，所述微型管位于其中。所述微型管20从穿过所述近端连接器12并超过远端连接器28。桥接片30位于近端连接器12和远端连接器28之间。
在如图3所示的实施例中，所述桥接片30显示为一个可以由金属材料制成的弹簧。在一示例中，远端连接器28可以由聚合物构成。远端连接器28可以包括穿过所述连接器28的通道32。微型管20穿过通道32。在一示例中，所述桥接片30被粘在近端连接器12内且位于远端连接器28内的通道之内。当所述远端连接器28未连接在所述导管接头且使用者扭动近端连接器12时，这种结构将使得所述桥接片30(例如弹簧)能够旋转。在一示例中，所述微型管20的远端延伸超出远端连接器28大约5-40mm。在另一示例中，所述微型管20的远端的远端延伸超出远端连接器28大约10-20mm。在另一示例中，所述微型管20的远端的远端延伸超出远端连接器28大约15mm。当所述注射器通过配合部件10与近端连接器12相配合时，其直接与微型管20相连接，该微型管位于所述近端连接器12内。因此所述注射器内容物直接被传送至所述适配器的所述微型管内，并且当所述导管接头被连接在远端连接器28时，内容物流出所述微型管20的远端流入所述导管接头。
图4-5展示了输送适配器的另一实施例，其展示了一个额外的位于远端连接器28的末端的远端旋转元件34。在一示例中，桥接片30粘在近端连接器12内(例如通过UV胶)以及粘在远端连接器28内。在将所述适配器与所述导管接头粘合之前使用者对所述近端连接器12的任何扭转都将导致远端连接器28的扭曲。在一实施例中，远端旋转元件34独立于和/或相对于远端连接器28自由旋转。元件34的旋转能力缓解了在弹簧桥接元件30上的很多压力，否则可能会造成发生在所述弹簧/桥接元件的一部分的单方面的扭转应力，特别是当所述适配器被固定在所述导管接头后。
在一示例中，微型管20可以由聚合物构成，或在另一示例中可以由金属材料构成。
在如图3-5所示的另一实施例中，可以使用一螺纹桥接片30代替所述弹簧桥接片30。所述螺纹桥接片30可以由金属或聚合物材料构成并且在表面具有螺纹。
在一示例中，所述桥接片30具有外凸螺纹并且远端连接器28具有与所述螺纹对应的凹部以相配合，如图6所示，因此所述远端连接器28的旋转将使得远端连接器28的向上或向下(近端或远端)移动。在另一示例中，所述桥接片30具有凹部并且远端连接器28具有与所述凹部对应的螺纹以相配合，因此所述远端连接器28的旋转将使得远端连接器28的向上或向下(近端或远端)移动。对于图4-5中所示的实施例，远端连接器28或远端旋转元件34可以具有螺纹或凹部以与所述桥接元件30相配合。或者，对于图4-5中所示的实施例，远端连接器28与远端旋转元件34均可以具有螺纹或凹部以与所述桥接元件30相配合。
如图3-5所示的实施例中的所述微型管20可以截止于所述导管储液器24之内或者可以完全超过所述导管储液器24。在一示例中，所述微型管20的远端延伸超出远端连接器28大约5-40mm。在另一示例中，所述微型管20的远端的远端延伸超出远端连接器28大约10-20mm。在另一示例中，所述微型管20的远端的远端延伸超出远端连接器28大约15mm。
不同的导管具有不同的接头和储液器尺寸。如图3-7所示的实施例可以被认为是一个通用适配器，因为所示微型管长度无需被定制以配合各种各样的导管接头。微型管20位于所述导管接头22内尽可能远端位置。远端连接器28和/或远端旋转元件34进而被拉伸(弹簧桥接片实施例)或被旋转(螺纹桥接片实施例)，从而远端连接器28(图3实施例)或远端旋转元件34(图4-6实施例)配合所述导管接头。当此部位被拉伸/旋转时，所述旋转元件34或远端连接器28(根据所述实施例)从而被旋紧在所述导管接头以确保连接。
使用如图3-6所示的所述通用的输送适配器输送高粘度液体(例如液体栓塞剂)的方法如下：所述导管、微导管或输送装置被生理盐水冲洗并且被导航至目标地点。所述导管被溶剂(例如生物相容的溶剂，诸如DMSO/二甲基亚砜)冲洗。所述导管接头22被溶剂(DMSO)所充满，以便移除空气气泡且使得空气气泡形成的机会降至最小。所述输送适配器的所述近端连接器12连接所述注射器，并且通过向输送适配器注入液体栓塞剂以清除所述输送适配器的空气。一旦清除完成，是微型管20位于所述导管接头22内。当所述微型管20位于所述导管接头22内，所述远端连接器28(图3实施例)和/或远端旋转元件34(图4-6实施例)被拉伸(弹簧桥接片30)或被旋转(螺纹桥接片30)以连接所述导管。当此部位被拉伸/旋转时，所述旋转元件34或远端连接器28(根据所述实施例)从而被旋紧在所述导管接头以确保连接。液体栓塞剂从而可以通过所述输送适配器，当所述导管被导航至所述目标治疗部位时通过所述导管被从所述注射器输送至目标治疗部位。
参考图7A-7B，展示了所述适配器的另一个实施例。近端连接器12通过在所述桥接片上的外螺纹和所述近端连接器12上的内螺纹与螺纹桥接片30相配合。但是，所述螺纹30A、30B的配合面对于所述近端连接器12是这样一种临界轴向力(即向上或向下)，将导致近端连接器12的外壁使得所述螺纹30A/30B扩大且脱离。其允许所述近端连接器12相对于所述螺纹桥接片30以一种棘轮式运动进行轴向运动(也即向上或向下)。一旦移除所述临界轴向力，所述近端连接器12的外壁将恢复至正常位置且所述螺纹30A、30B将重新咬合。在一较佳的实施例中，所述螺纹30A/30B的所述配合面为如图7B所示的斜坡面。
在一实施例中，所述近端连接器12被配置为使用者能够将所述近端连接器12的外部上边缘挤压在一起，从而迫使近端连接器的下边缘向外折叠。这导致所述螺纹30A、30B的脱离并且允许使用者自如地上下移动所述近端连接器12。一旦到达需要的位置，使用者释放所述近端连接器12的外部上边缘且所述近端连接器12的下边缘恢复为非折叠状态，并且螺纹30A/30B因而重新咬合。在本实施例中，所述近端连接器12可以采用稍凹的形状以使得对应此挤压压力能够产生这样一种折叠。在一示例中，所述近端连接器12可以包括抓握部件(即用于用户抓握的粗糙部件)，其中，使用者为了自由移动近端连接器12将挤压以开始折叠。
继续参考图7A、7B，在使用中，使用者决定微型管20延伸超过远端连接器28的需要的距离。然后使用者以以上所描述的方式在所述近端连接器12上施加轴向力，以将所述近端连接器12以及其所附的微型管20移动至前述距离。使用者能够通过所述近端连接器12相对于所述螺纹桥接片30的旋转对所需要的距离进行“微调”。然后所述适配器准备将所述微型管20插入所述导管接头。然后使用者通过将所述远端连接器28旋紧在所述导管接头上(例如通过旋锁接头连接)以将所述导管与所述适配器紧固。使用者也可以将所述注射器固定在位于所述近端连接器12顶端的所述旋锁接头10上。
虽然本发明已被描述在特定的实施例和应用中，普通本领域技术人员在其教导的启发之下可以得到其他的实施例和修改，而不脱离请求保护的本发明的精神或是超越请求保护的本发明的范围。相应地，可以理解，文中所述的附图及说明所提供的示例的方式是为了帮助对发明的理解而不应被解释为对范围的限制。
Claims (13)
1.一种适配器，包括：
第一连接器，其适用于连接注射器；
独立于所述第一连接器的第二连接器，其适用于连接导管接头；以及
管，其从所述第一连接器延伸穿过所述第二连接器，并且当所述第二连接器连接所述导管接头时，所述管延伸超出所述第二连接器从而绕过所述导管接头的储液器；
所述第二连接器的位置可在所述管上调节。
2.根据权利要求1所述的适配器，还包括桥接片，所述桥接片包括连接所述第一连接器和所述第二连接器的弹簧。
3.根据权利要求1所述的适配器，还包括桥接片，所述桥接片包括螺纹。
4.根据权利要求1所述的适配器，其中，所述第二连接器可相对所述第一连接器独立旋转。
5.一种注射器与导管的适配方法，包括：
将适配器的一端连接注射器；
将所述适配器的管状部件插入在导管接头内，绕过所述导管接头的储液器；
相对所述管状部件移动所述适配器的第二端；以及
将所述适配器的所述第二端与所述导管接头固定。
6.根据权利要求5所述的方法，其中，相对所述管状部件移动所述适配器的第二端包括用弹簧弹力约束所述移动。
7.根据权利要求5所述的方法，其中，相对所述管状部件移动所述适配器的第二端包括用螺纹运动约束所述移动。
8.一种栓塞剂输送系统，包括：
注射器，其包含栓塞剂材料；以及
适配器，其包括：
第一连接器，其适用于连接所述注射器；
第二连接器，其适用于连接导管接头；以及，
管，其从所述第一连接器延伸并超出所述第二连接器，所述第二连接器的位置可在所述管上调节至超出导管接头的储液器的位置。
9.根据权利要求8所述的栓塞剂输送系统，还包括桥接片，所述桥接片被设置在所述第一连接器和所述第二连接器之间。
10.根据权利要求9所述的栓塞剂输送系统，其中，所述桥接片包括螺旋螺纹。
11.根据权利要求8所述的栓塞剂输送系统，其中，所述第二连接器可相对所述第一连接器独立旋转。
12.根据权利要求8所述的栓塞剂输送系统，其中，当所述第二连接器连接所述导管接头时，所述管延伸超出所述第二连接器从而绕过所述导管接头的储液器。
13.根据权利要求8所述的栓塞剂输送系统，其中，当所述第二连接器连接所述导管接头时，所述适配器的所述管延伸超出所述第二连接器，以使得所述管的端部位于所述导管接头的储液器内。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919664P | 2013-12-20 | 2013-12-20 | |
| US61/919,664 | 2013-12-20 | ||
| PCT/US2014/071711 WO2015095815A1 (en) | 2013-12-20 | 2014-12-19 | Delivery adapter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106029157A CN106029157A (zh) | 2016-10-12 |
| CN106029157B true CN106029157B (zh) | 2019-09-17 |
Family
ID=53398945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480076090.0A Active CN106029157B (zh) | 2013-12-20 | 2014-12-19 | 输送适配器、注射器与导管的适配方法和栓塞剂输送系统 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US9833604B2 (zh) |
| EP (1) | EP3082939B1 (zh) |
| JP (2) | JP6412137B2 (zh) |
| CN (1) | CN106029157B (zh) |
| WO (1) | WO2015095815A1 (zh) |
Families Citing this family (127)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0617652A2 (pt) | 2005-10-19 | 2011-08-02 | Pulsar Vascular Inc | métodos e sistemas para incisão endovascular e reparo de defeitos de tecido e lúmen |
| US9402707B2 (en) | 2008-07-22 | 2016-08-02 | Neuravi Limited | Clot capture systems and associated methods |
| ES2879278T3 (es) | 2008-09-05 | 2021-11-22 | Pulsar Vascular Inc | Sistemas para sostener u ocluir una abertura o cavidad fisiológica |
| EP2629684B1 (en) | 2010-10-22 | 2018-07-25 | Neuravi Limited | Clot engagement and removal system |
| US11259824B2 (en) | 2011-03-09 | 2022-03-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| EP2683309B1 (en) | 2011-03-09 | 2021-04-21 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
| JP6219270B2 (ja) | 2011-06-03 | 2017-10-25 | パルサー バスキュラー インコーポレイテッド | 動脈瘤装置 |
| CA2850783C (en) | 2011-10-05 | 2020-01-07 | Pulsar Vascular, Inc. | Devices, systems and methods for enclosing an anatomical opening |
| US10603157B2 (en) | 2013-03-13 | 2020-03-31 | DePuy Synthes Products, Inc. | Braid implant delivery and retraction device with distal engagement |
| US10561509B2 (en) | 2013-03-13 | 2020-02-18 | DePuy Synthes Products, Inc. | Braided stent with expansion ring and method of delivery |
| US9433429B2 (en) | 2013-03-14 | 2016-09-06 | Neuravi Limited | Clot retrieval devices |
| EP2967611B1 (en) | 2013-03-14 | 2019-01-16 | Neuravi Limited | Devices for removal of acute blockages from blood vessels |
| JP2016513505A (ja) | 2013-03-14 | 2016-05-16 | ニューラヴィ・リミテッド | 血管から閉塞血餅を除去するための血餅回収デバイス |
| US9833604B2 (en) * | 2013-12-20 | 2017-12-05 | Microvention, Inc. | Delivery adapter |
| US10285720B2 (en) | 2014-03-11 | 2019-05-14 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| US11076860B2 (en) | 2014-03-31 | 2021-08-03 | DePuy Synthes Products, Inc. | Aneurysm occlusion device |
| US11154302B2 (en) | 2014-03-31 | 2021-10-26 | DePuy Synthes Products, Inc. | Aneurysm occlusion device |
| WO2015189354A1 (en) | 2014-06-13 | 2015-12-17 | Neuravi Limited | Devices for removal of acute blockages from blood vessels |
| US10265086B2 (en) | 2014-06-30 | 2019-04-23 | Neuravi Limited | System for removing a clot from a blood vessel |
| US9918718B2 (en) | 2014-08-08 | 2018-03-20 | DePuy Synthes Products, Inc. | Embolic coil delivery system with retractable mechanical release mechanism |
| US10206796B2 (en) | 2014-08-27 | 2019-02-19 | DePuy Synthes Products, Inc. | Multi-strand implant with enhanced radiopacity |
| US9782178B2 (en) | 2014-09-19 | 2017-10-10 | DePuy Synthes Products, Inc. | Vasculature occlusion device detachment system with tapered corewire and heater activated fiber detachment |
| US10617435B2 (en) | 2014-11-26 | 2020-04-14 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11253278B2 (en) | 2014-11-26 | 2022-02-22 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| EP3223723B1 (en) | 2014-11-26 | 2020-01-08 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
| US10285710B2 (en) | 2016-06-01 | 2019-05-14 | DePuy Synthes Products, Inc. | Endovascular detachment system with flexible distal end and heater activated detachment |
| MX2019001899A (es) | 2016-08-17 | 2019-09-18 | Neuravi Ltd | Un sistema de recuperación de coágulos para eliminar coágulos oclusivos de un vaso sanguíneo. |
| US10076428B2 (en) | 2016-08-25 | 2018-09-18 | DePuy Synthes Products, Inc. | Expansion ring for a braided stent |
| CA3035706A1 (en) | 2016-09-06 | 2018-03-15 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
| US10292851B2 (en) | 2016-09-30 | 2019-05-21 | DePuy Synthes Products, Inc. | Self-expanding device delivery apparatus with dual function bump |
| US10517708B2 (en) | 2016-10-26 | 2019-12-31 | DePuy Synthes Products, Inc. | Multi-basket clot capturing device |
| US10905853B2 (en) | 2017-01-17 | 2021-02-02 | DePuy Synthes Products, Inc. | System and method for delivering a catheter |
| US10881497B2 (en) | 2017-01-26 | 2021-01-05 | DePuy Synthes Products, Inc. | Composite vascular flow diverter |
| CN110352077B (zh) * | 2017-02-06 | 2022-05-27 | 微仙美国有限公司 | 输送适配器 |
| CN110545739A (zh) | 2017-02-23 | 2019-12-06 | 德普伊新特斯产品公司 | 动脉瘤装置及递送系统 |
| US10806462B2 (en) | 2017-12-21 | 2020-10-20 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with split tube and cylindrical coupling |
| US10751065B2 (en) | 2017-12-22 | 2020-08-25 | DePuy Synthes Products, Inc. | Aneurysm device and delivery system |
| US10905430B2 (en) | 2018-01-24 | 2021-02-02 | DePuy Synthes Products, Inc. | Aneurysm device and delivery system |
| US10786259B2 (en) | 2018-03-30 | 2020-09-29 | DePuy Synthes Products, Inc. | Split balloon assist device and method for using the same |
| US10918390B2 (en) | 2018-03-30 | 2021-02-16 | DePuy Synthes Products, Inc. | Helical balloon assist device and method for using the same |
| US10806461B2 (en) | 2018-04-27 | 2020-10-20 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with split tube |
| US11596412B2 (en) | 2018-05-25 | 2023-03-07 | DePuy Synthes Products, Inc. | Aneurysm device and delivery system |
| US11058430B2 (en) | 2018-05-25 | 2021-07-13 | DePuy Synthes Products, Inc. | Aneurysm device and delivery system |
| US10939915B2 (en) | 2018-05-31 | 2021-03-09 | DePuy Synthes Products, Inc. | Aneurysm device and delivery system |
| US10667833B2 (en) | 2018-06-08 | 2020-06-02 | Neuravi Limited | Guidewire with an atraumatic clot-circumventing configured distal end for use in an endovascular medical system |
| US10898216B2 (en) | 2018-06-13 | 2021-01-26 | DePuy Synthes Products, Inc. | Vasculature obstruction capture device |
| AU2019204522A1 (en) | 2018-07-30 | 2020-02-13 | DePuy Synthes Products, Inc. | Systems and methods of manufacturing and using an expansion ring |
| US10905431B2 (en) | 2018-08-03 | 2021-02-02 | DePuy Synthes Products, Inc. | Spiral delivery system for embolic braid |
| US10456280B1 (en) | 2018-08-06 | 2019-10-29 | DePuy Synthes Products, Inc. | Systems and methods of using a braided implant |
| US10278848B1 (en) | 2018-08-06 | 2019-05-07 | DePuy Synthes Products, Inc. | Stent delivery with expansion assisting delivery wire |
| US11051825B2 (en) | 2018-08-08 | 2021-07-06 | DePuy Synthes Products, Inc. | Delivery system for embolic braid |
| US10813780B2 (en) | 2018-08-08 | 2020-10-27 | DePuy Synthes Products, Inc. | Intraluminal implant delivery system and method |
| US10842498B2 (en) | 2018-09-13 | 2020-11-24 | Neuravi Limited | Systems and methods of restoring perfusion to a vessel |
| EP3626212A3 (en) | 2018-09-20 | 2020-07-22 | DePuy Synthes Products, Inc. | Stent with shaped wires |
| US11123077B2 (en) | 2018-09-25 | 2021-09-21 | DePuy Synthes Products, Inc. | Intrasaccular device positioning and deployment system |
| US11406416B2 (en) | 2018-10-02 | 2022-08-09 | Neuravi Limited | Joint assembly for vasculature obstruction capture device |
| US11253287B2 (en) | 2018-10-04 | 2022-02-22 | Neuravi Limited | Retrograde blood flow occlusion flushing device |
| US11076861B2 (en) | 2018-10-12 | 2021-08-03 | DePuy Synthes Products, Inc. | Folded aneurysm treatment device and delivery method |
| US11406392B2 (en) | 2018-12-12 | 2022-08-09 | DePuy Synthes Products, Inc. | Aneurysm occluding device for use with coagulating agents |
| US11147562B2 (en) | 2018-12-12 | 2021-10-19 | DePuy Synthes Products, Inc. | Systems and methods for embolic implant detachment |
| US11272939B2 (en) | 2018-12-18 | 2022-03-15 | DePuy Synthes Products, Inc. | Intrasaccular flow diverter for treating cerebral aneurysms |
| US11039944B2 (en) | 2018-12-27 | 2021-06-22 | DePuy Synthes Products, Inc. | Braided stent system with one or more expansion rings |
| US11134953B2 (en) | 2019-02-06 | 2021-10-05 | DePuy Synthes Products, Inc. | Adhesive cover occluding device for aneurysm treatment |
| US11273285B2 (en) | 2019-02-07 | 2022-03-15 | DePuy Synthes Products, Inc. | Ancillary device for detaching implants |
| EP4000540B1 (en) | 2019-03-04 | 2024-02-14 | Neuravi Limited | Actuated clot retrieval catheter |
| US11382633B2 (en) | 2019-03-06 | 2022-07-12 | DePuy Synthes Products, Inc. | Strut flow diverter for cerebral aneurysms and methods for preventing strut entanglement |
| US11337706B2 (en) | 2019-03-27 | 2022-05-24 | DePuy Synthes Products, Inc. | Aneurysm treatment device |
| US11185334B2 (en) | 2019-03-28 | 2021-11-30 | DePuy Synthes Products, Inc. | Single lumen reduced profile occlusion balloon catheter |
| US11051928B2 (en) | 2019-04-11 | 2021-07-06 | Neuravi Limited | Floating carotid filter |
| US11607531B2 (en) | 2019-05-09 | 2023-03-21 | Neuravi Limited | Balloon catheter with venting of residual air in a proximal direction |
| US11957855B2 (en) | 2019-05-09 | 2024-04-16 | Neuravi Limited | Balloon guide catheter with positive venting of residual air |
| US11931522B2 (en) | 2019-05-09 | 2024-03-19 | Neuravi Limited | Inflation lumen kink protection and balloon profile |
| US11571553B2 (en) | 2019-05-09 | 2023-02-07 | Neuravi Limited | Balloon guide catheter with thermally expandable material |
| USD959659S1 (en) | 2019-05-10 | 2022-08-02 | DePuy Synthes Products, Inc. | Implant release handle |
| US10653425B1 (en) | 2019-05-21 | 2020-05-19 | DePuy Synthes Products, Inc. | Layered braided aneurysm treatment device |
| US11602350B2 (en) | 2019-12-05 | 2023-03-14 | DePuy Synthes Products, Inc. | Intrasaccular inverting braid with highly flexible fill material |
| US11497504B2 (en) | 2019-05-21 | 2022-11-15 | DePuy Synthes Products, Inc. | Aneurysm treatment with pushable implanted braid |
| US11413046B2 (en) | 2019-05-21 | 2022-08-16 | DePuy Synthes Products, Inc. | Layered braided aneurysm treatment device |
| US11278292B2 (en) | 2019-05-21 | 2022-03-22 | DePuy Synthes Products, Inc. | Inverting braided aneurysm treatment system and method |
| US11607226B2 (en) | 2019-05-21 | 2023-03-21 | DePuy Synthes Products, Inc. | Layered braided aneurysm treatment device with corrugations |
| US11672542B2 (en) | 2019-05-21 | 2023-06-13 | DePuy Synthes Products, Inc. | Aneurysm treatment with pushable ball segment |
| US11109939B2 (en) | 2019-06-14 | 2021-09-07 | DePuy Synthes Products, Inc. | Intravascular devices with radiopaque body markers |
| US11406403B2 (en) | 2019-06-14 | 2022-08-09 | Neuravi Limited | Visibility of mechanical thrombectomy device during diagnostic imaging |
| US11253265B2 (en) | 2019-06-18 | 2022-02-22 | DePuy Synthes Products, Inc. | Pull wire detachment for intravascular devices |
| US11207494B2 (en) | 2019-07-03 | 2021-12-28 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant distal portion |
| US11426174B2 (en) | 2019-10-03 | 2022-08-30 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant mechanical release |
| US11266426B2 (en) | 2019-07-10 | 2022-03-08 | DePuy Synthes Products, Inc. | Streamlined treatment of clot removal, angioplasty and prevention of restenosis using a single integrated intravascular device |
| US11266427B2 (en) | 2019-07-10 | 2022-03-08 | Neuravi Limited | Self-expanding intravascular medical device |
| US11395675B2 (en) | 2019-07-11 | 2022-07-26 | DePuy Synthes Products, Inc. | Clot retriever cleaning for reinsertion |
| EP3791815A1 (en) | 2019-09-11 | 2021-03-17 | Neuravi Limited | Expandable mouth catheter |
| US11439403B2 (en) | 2019-09-17 | 2022-09-13 | DePuy Synthes Products, Inc. | Embolic coil proximal connecting element and stretch resistant fiber |
| US11712231B2 (en) | 2019-10-29 | 2023-08-01 | Neuravi Limited | Proximal locking assembly design for dual stent mechanical thrombectomy device |
| US11376013B2 (en) | 2019-11-18 | 2022-07-05 | DePuy Synthes Products, Inc. | Implant delivery system with braid cup formation |
| US11628282B2 (en) | 2019-11-25 | 2023-04-18 | Neuravi Limited | No preparation balloon guide catheter |
| US11779364B2 (en) | 2019-11-27 | 2023-10-10 | Neuravi Limited | Actuated expandable mouth thrombectomy catheter |
| US11839725B2 (en) | 2019-11-27 | 2023-12-12 | Neuravi Limited | Clot retrieval device with outer sheath and inner catheter |
| US11517340B2 (en) | 2019-12-03 | 2022-12-06 | Neuravi Limited | Stentriever devices for removing an occlusive clot from a vessel and methods thereof |
| US11457926B2 (en) | 2019-12-18 | 2022-10-04 | DePuy Synthes Products, Inc. | Implant having an intrasaccular section and intravascular section |
| CN111134756B (zh) * | 2019-12-30 | 2021-01-19 | 西安交通大学 | 一种防止异位栓塞的纤维慢性栓塞装置 |
| US11457922B2 (en) | 2020-01-22 | 2022-10-04 | DePuy Synthes Products, Inc. | Medical device delivery member with flexible stretch resistant distal portion |
| US11957354B2 (en) | 2020-02-10 | 2024-04-16 | DePuy Synthes Products, Inc. | Aneurysm implant support device |
| US11432822B2 (en) | 2020-02-14 | 2022-09-06 | DePuy Synthes Products, Inc. | Intravascular implant deployment system |
| US11633198B2 (en) | 2020-03-05 | 2023-04-25 | Neuravi Limited | Catheter proximal joint |
| US11944327B2 (en) | 2020-03-05 | 2024-04-02 | Neuravi Limited | Expandable mouth aspirating clot retrieval catheter |
| US11883043B2 (en) | 2020-03-31 | 2024-01-30 | DePuy Synthes Products, Inc. | Catheter funnel extension |
| US11759217B2 (en) | 2020-04-07 | 2023-09-19 | Neuravi Limited | Catheter tubular support |
| US11871946B2 (en) | 2020-04-17 | 2024-01-16 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11730501B2 (en) | 2020-04-17 | 2023-08-22 | Neuravi Limited | Floating clot retrieval device for removing clots from a blood vessel |
| US11717308B2 (en) | 2020-04-17 | 2023-08-08 | Neuravi Limited | Clot retrieval device for removing heterogeneous clots from a blood vessel |
| US11523831B2 (en) | 2020-04-30 | 2022-12-13 | DePuy Synthes Products, Inc. | Intrasaccular flow diverter |
| US11737771B2 (en) | 2020-06-18 | 2023-08-29 | Neuravi Limited | Dual channel thrombectomy device |
| US11937836B2 (en) | 2020-06-22 | 2024-03-26 | Neuravi Limited | Clot retrieval system with expandable clot engaging framework |
| US11395669B2 (en) | 2020-06-23 | 2022-07-26 | Neuravi Limited | Clot retrieval device with flexible collapsible frame |
| US11439418B2 (en) | 2020-06-23 | 2022-09-13 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11951026B2 (en) | 2020-06-30 | 2024-04-09 | DePuy Synthes Products, Inc. | Implantable medical device detachment system with flexible braid section |
| US11864781B2 (en) | 2020-09-23 | 2024-01-09 | Neuravi Limited | Rotating frame thrombectomy device |
| US11786698B2 (en) | 2020-12-08 | 2023-10-17 | DePuy Synthes Products, Inc. | Catheter with textured surface |
| US11826520B2 (en) | 2020-12-08 | 2023-11-28 | DePuy Synthes Products, Inc. | Catheter designs for enhanced column strength |
| US11937837B2 (en) | 2020-12-29 | 2024-03-26 | Neuravi Limited | Fibrin rich / soft clot mechanical thrombectomy device |
| US11872354B2 (en) | 2021-02-24 | 2024-01-16 | Neuravi Limited | Flexible catheter shaft frame with seam |
| US11974764B2 (en) | 2021-06-04 | 2024-05-07 | Neuravi Limited | Self-orienting rotating stentriever pinching cells |
| US11937839B2 (en) | 2021-09-28 | 2024-03-26 | Neuravi Limited | Catheter with electrically actuated expandable mouth |
| US11751881B2 (en) | 2021-11-26 | 2023-09-12 | DePuy Synthes Products, Inc. | Securement wire withstanding forces during deployment of implantable intravascular treatment device using a delivery and detachment system |
| US11844490B2 (en) | 2021-12-30 | 2023-12-19 | DePuy Synthes Products, Inc. | Suture linkage for inhibiting premature embolic implant deployment |
| US11937824B2 (en) | 2021-12-30 | 2024-03-26 | DePuy Synthes Products, Inc. | Implant detachment systems with a modified pull wire |
| US11937825B2 (en) | 2022-03-02 | 2024-03-26 | DePuy Synthes Products, Inc. | Hook wire for preventing premature embolic implant detachment |
| US11937826B2 (en) | 2022-03-14 | 2024-03-26 | DePuy Synthes Products, Inc. | Proximal link wire for preventing premature implant detachment |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4187848A (en) * | 1977-07-18 | 1980-02-12 | The Kendall Company | Adapter assembly |
| US5122123A (en) * | 1991-01-30 | 1992-06-16 | Vaillancourt Vincent L | Closed system connector assembly |
| EP1243285A1 (en) * | 1999-12-17 | 2002-09-25 | Terumo Kabushiki Kaisha | Connector |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2923298B2 (ja) * | 1989-02-06 | 1999-07-26 | テルモ株式会社 | 医療用ガイドワイヤ |
| US5509911A (en) * | 1992-11-27 | 1996-04-23 | Maxxim Medical, Inc. | Rotating adapter for a catheterization system |
| US6511472B1 (en) | 1999-05-21 | 2003-01-28 | Microtherapeutics, Inc. | Interface needle and method for creating a blunt interface between delivered liquids |
| US7195615B2 (en) * | 2003-05-14 | 2007-03-27 | Boston Scientific Scimed, Inc. | System for providing a medical device with anti-microbial properties |
| WO2009045793A1 (en) * | 2007-09-28 | 2009-04-09 | Access Closure, Inc. | Apparatus and methods for sealing a vascular puncture |
| US9414990B2 (en) * | 2013-03-15 | 2016-08-16 | Becton Dickinson and Company Ltd. | Seal system for cannula |
| US9833604B2 (en) * | 2013-12-20 | 2017-12-05 | Microvention, Inc. | Delivery adapter |
-
2014
- 2014-12-19 US US14/578,164 patent/US9833604B2/en active Active
- 2014-12-19 WO PCT/US2014/071711 patent/WO2015095815A1/en active Application Filing
- 2014-12-19 JP JP2016541572A patent/JP6412137B2/ja active Active
- 2014-12-19 CN CN201480076090.0A patent/CN106029157B/zh active Active
- 2014-12-19 EP EP14871442.1A patent/EP3082939B1/en active Active
-
2017
- 2017-11-03 US US15/803,694 patent/US10668264B2/en active Active
-
2018
- 2018-09-27 JP JP2018183008A patent/JP6577111B2/ja active Active
-
2020
- 2020-04-23 US US16/856,727 patent/US11666742B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4187848A (en) * | 1977-07-18 | 1980-02-12 | The Kendall Company | Adapter assembly |
| US5122123A (en) * | 1991-01-30 | 1992-06-16 | Vaillancourt Vincent L | Closed system connector assembly |
| EP1243285A1 (en) * | 1999-12-17 | 2002-09-25 | Terumo Kabushiki Kaisha | Connector |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6412137B2 (ja) | 2018-10-24 |
| US20150174389A1 (en) | 2015-06-25 |
| JP6577111B2 (ja) | 2019-09-18 |
| WO2015095815A1 (en) | 2015-06-25 |
| US20180064922A1 (en) | 2018-03-08 |
| EP3082939A4 (en) | 2017-08-16 |
| JP2017503574A (ja) | 2017-02-02 |
| US9833604B2 (en) | 2017-12-05 |
| US11666742B2 (en) | 2023-06-06 |
| EP3082939B1 (en) | 2020-12-02 |
| JP2019048065A (ja) | 2019-03-28 |
| CN106029157A (zh) | 2016-10-12 |
| EP3082939A1 (en) | 2016-10-26 |
| US10668264B2 (en) | 2020-06-02 |
| US20200246607A1 (en) | 2020-08-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106029157B (zh) | 输送适配器、注射器与导管的适配方法和栓塞剂输送系统 | |
| US20100094260A1 (en) | Luer lock adapter | |
| US6722705B2 (en) | Medical tubing connector | |
| US5047021A (en) | Male luer lock medical fitting | |
| US6453956B2 (en) | Needle safe transfer guard | |
| CN106999703B (zh) | 双材料y形连接器 | |
| CN103648579B (zh) | 药物输送装置和适配器 | |
| JP2004524107A (ja) | 高圧注入システム | |
| CN102525601A (zh) | 隧道器装置及其使用方法 | |
| CN105431188A (zh) | 流体输送连接件 | |
| CN108472477A (zh) | 用于医疗导管的扩口式鲁尔连接器的系统和方法 | |
| US11779746B2 (en) | Fluid transfer connectors | |
| JP2014520621A (ja) | 薬物送達装置およびアダプタ | |
| CN105407960B (zh) | 用于结合有相对倒钩的螺纹连接的机械摩擦增强 | |
| US20200384256A1 (en) | Fluid delivery adapter for vascular compression devices and associated methods | |
| US20090299270A1 (en) | Line of perfusion for liquid of medical treatment | |
| US20230304614A1 (en) | Tubing retention device | |
| US20140276617A1 (en) | Directional Guide Catheter Assembly | |
| CN114366212B (zh) | 一种用于临时性动脉栓塞的明胶海绵条输送系统 | |
| US9919143B2 (en) | Medical connection device with valve and method | |
| CN110352077A (zh) | 输送适配器 | |
| US20190314057A1 (en) | Occludable introducer needle | |
| CN107485426A (zh) | 一种心血管内科用插管夹持装置 | |
| CN106215315A (zh) | 一种可压紧导尿管的转换接头 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: American California Applicant after: Micro cents America Limited Address before: American California Applicant before: Microvention, INC. |
|
| CB02 | Change of applicant information | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |