CN105963307B - 一种罗汉果醇衍生物单体及其组合物的用途 - Google Patents

一种罗汉果醇衍生物单体及其组合物的用途 Download PDF

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Publication number
CN105963307B
CN105963307B CN201610296685.8A CN201610296685A CN105963307B CN 105963307 B CN105963307 B CN 105963307B CN 201610296685 A CN201610296685 A CN 201610296685A CN 105963307 B CN105963307 B CN 105963307B
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Prior art keywords
momordica grosvenori
cancer
alcohol derivatives
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grosvenori alcohol
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Chinese (zh)
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CN105963307A (zh
Inventor
余佩华
邓跃敏
钟牧源
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Shenzhen Yinuo Biopharmaceutical Co Ltd
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Shenzhen Yinuo Biopharmaceutical Co Ltd
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Priority to CN201610296685.8A priority Critical patent/CN105963307B/zh
Priority to PCT/CN2016/089199 priority patent/WO2017190419A1/fr
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201610296685.8A 2016-05-06 2016-05-06 一种罗汉果醇衍生物单体及其组合物的用途 Active CN105963307B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201610296685.8A CN105963307B (zh) 2016-05-06 2016-05-06 一种罗汉果醇衍生物单体及其组合物的用途
PCT/CN2016/089199 WO2017190419A1 (fr) 2016-05-06 2016-07-07 Utilisations de monomère dérivé de mogrol et composition correspondante

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610296685.8A CN105963307B (zh) 2016-05-06 2016-05-06 一种罗汉果醇衍生物单体及其组合物的用途

Publications (2)

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CN105963307A CN105963307A (zh) 2016-09-28
CN105963307B true CN105963307B (zh) 2019-08-09

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CN (1) CN105963307B (fr)
WO (1) WO2017190419A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105832748B (zh) * 2016-05-06 2019-06-07 深圳以诺生物制药有限公司 一种从罗汉果总皂苷中制备罗汉果醇衍生物的方法
CN108578702B (zh) * 2018-05-24 2022-11-29 深圳以诺生物制药有限公司 一种稀有人参皂苷的混合物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101033244A (zh) * 2007-04-05 2007-09-12 上海交通大学 罗汉果醇的提纯制备方法
CN102526073A (zh) * 2012-01-06 2012-07-04 复旦大学 罗汉果醇h9在制备抗肿瘤药物中的应用
CN104042620A (zh) * 2013-03-12 2014-09-17 复旦大学 罗汉果醇在制备肿瘤多药耐药逆转剂中的用途
CN104510736A (zh) * 2013-09-26 2015-04-15 华安医学股份有限公司 活化ampk的化合物及其使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066611A1 (fr) * 1999-04-30 2000-11-09 Arch Development Corporation Derives steroides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101033244A (zh) * 2007-04-05 2007-09-12 上海交通大学 罗汉果醇的提纯制备方法
CN102526073A (zh) * 2012-01-06 2012-07-04 复旦大学 罗汉果醇h9在制备抗肿瘤药物中的应用
CN104042620A (zh) * 2013-03-12 2014-09-17 复旦大学 罗汉果醇在制备肿瘤多药耐药逆转剂中的用途
CN104510736A (zh) * 2013-09-26 2015-04-15 华安医学股份有限公司 活化ampk的化合物及其使用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AMPK在姜黄素诱导CaOV3人卵巢癌细胞凋亡中的作用;潘巍等;《现代生物医学进展》;20091231;第9卷(第4期);第637-640、657页 *
Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle;Xu-bing Chen等;《Bioorganic & Medicinal Chemistry》;20110822;第19卷;第5776–5781页 *

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WO2017190419A1 (fr) 2017-11-09
CN105963307A (zh) 2016-09-28

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