CN105942523A - Green plum-containing healthcare food composition with throat clearing effect and preparation method thereof - Google Patents

Green plum-containing healthcare food composition with throat clearing effect and preparation method thereof Download PDF

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Publication number
CN105942523A
CN105942523A CN201610393297.1A CN201610393297A CN105942523A CN 105942523 A CN105942523 A CN 105942523A CN 201610393297 A CN201610393297 A CN 201610393297A CN 105942523 A CN105942523 A CN 105942523A
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parts
radix
food composition
health
armeniaca mume
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钱书元
邹伟权
缪来耿
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Huizhou Tongfukang Biotechnology Co Ltd
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Huizhou Tongfukang Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
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    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention belongs to the field of healthcare products, and relates to a green plum-containing healthcare food composition with the throat clearing effect and a preparation method thereof. The composition is prepared from green plums, radix platycodonis, herba taraxaci, fructus crataegi, herba verbenae, radix rehmanniae, periostracum cicada, herba menthae, licorice roots, kudzuvine roots and radix polygoni multiflori according to a certain proportion. The healthcare food composition is prepared from the green plums and the pure natural Chinese herbs, is scientific and reasonable in compatibility and distinct in primary and secondary, has the effects of clearing away heat and toxic materials, relieving sore throat and wetting the throat, astringing kidney qi to generate sperms and expelling wind and eliminating heat, is simple in component and few in toxic and side effect and has the multiple effects of achieving throat healthcare, preventing throat diseases and effectively relieving and treating the throat diseases.

Description

A kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. and preparation method
Technical field
The invention belongs to field of health care products, be specifically related to a kind of containing Armeniaca mume Sieb., there is moistening and cleaning throat effect Health-care food composition and preparation method.
Background technology
Pharyngitis refers to the inflammatory reaction of pharyngeal mucosa and submucous tissue, is often upper respiratory tract sense A part for dye.Now, due to atmospheric pollution, ecological deterioration, excessive pungent diet and cigarette The stimulation of wine, makes laryngopharyngeal diseases sickness rate substantially increase, is increasingly becoming be detrimental to health Big factor.
According to course of disease length and the difference of pathological change character, pharyngitis can be divided into acute pharyngitis, slowly The property big class of pharyngitis two.Wherein, chronic pharyngitis course of disease slower development, normal and adjacent organs or complete Body disease is also deposited, such as sinusitis, proventriculus type residual or retention abscess, pharyngeal bursitis etc..Acute Pharyngitis is pharyngeal mucous membrane, and involves under mucosa and adenoid acute inflammation, is often secondary to acute After rhinitis or acute tonsil or be the part of upper respiratory tract infection.The master of acute pharyngolaryngitis Wanting symptom is that onset is anxious, from the beginning of time pharyngeal be dried, scorching hot, pain then, pharynx when swallowing saliva Pain often than becomes apparent from when taking food, and can occur together heat, headache, inappetence and extremities aching pain, Invade and throat, can neigh and cough by accompanying sound.The cardinal symptom of chronic pharyngolaryngitis is pharyngeal discomfort, dry, Itch, swollen, secretions is many and causalgia, easy to dry, has foreign body sensation, and not out can not swallow. Above symptom especially can after irritable food the most, edible of speaking, tired or Changes in weather time Increase the weight of.
At present for the treatment of pharyngitis, doctor trained in Western medicine opinion metronidazole, Dobell's solution etc. are gargled Liquid, the buccal tablet such as buccal cydiodine, Anji buccal tablet, and use antipyretic analgesic medicine, as multiple Side's aspirin etc..Although these Drug therapys have the advantage of instant effect, taking convenience, energy Alleviate the disease in a period of time, but, usually curative effect is low, treatment recurrent exerbation the most thorough, easy, bad Reaction is many.Even if these medicines of long-term taking are the most all extremely difficult to effect a radical cure the effect of pharyngitis, on the contrary Liver, the kidney of human body can be caused serious damage, and produce drug resistance.
Card opinion is controlled, and pharyngitis is divided into two cards: the smoked bright lung system of heresy of (1) such as affection due to external wind and heat, or lung, Stomach two is through hot and suffocating upper heap soil or fertilizer over and around the roots, and causes laryngopharynx swelling and pain, true heat syndrome, and method for the treatment of is relieving sore-throat by clearing away heat, detumescence Pain relieving；(2) profit throat, hyperactivity of deficient fire can not be gone up such as kidney yin, also can cause laryngopharynx swelling and pain, belong to the moon Deficiency syndrome, method for the treatment of is nourishing YIN to lower pathogenic fire, replenishing YIN and removing heat.
Chinese patent application 201210455194.5 discloses the health-care product buccal tablet for pharyngitis, Composition and weight proportion thereof that this health-care product buccal tablet being used for pharyngitis contains be: Flos Lonicerae extract 20 parts, Fructus Forsythiae extract 20 parts, Semen Sterculiae Lychnophorae extract 20 parts, Flos Chrysanthemi extract 15 parts, Herba Schizonepetae extract 10 parts, Caulis Perillae extract 10 parts, Radix Scutellariae extract 15 parts, Radix Scrophulariae are extracted Thing 20 parts, taurine 75 parts, 68 parts of mannitol, aspartame 48 parts, Mentholum 72 Part, magnesium stearate 12 parts.This buccal tablet is made up of pure Chinese medicinal ingredients completely, have replenishing YIN and removing heat, Effect of relieving sore throat and pain.
Chinese patent application 201210471546.6 discloses a kind of health care for dysphagia Savoring oral liquid, crude drug composition and weight proportion thereof that it contains are Radix Codonopsis 30 parts, the Radix Astragali 15 Part, 15 parts of Poria, 5 parts of Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Polygoni Multiflori 12 parts, 15 parts of Fructus Jujubae.Tool There are invigorating the spleen and benefiting QI, effect of emergency feed, for achalasia of cardia and esophagus.
Although the health care medicine in the market with moistening and cleaning throat effect is of a great variety, but comprehensive nourishing Effect, and has relieving sore throat and pain, replenishing YIN and removing heat, alleviates dry laryngopharynx, dry hoarseness of itching, scorching hot The health care medicine of pain is the most few.Current Chinese drug preparation technique mostly falls behind, and method is extensive simply, Effective ingredient in ingredients can not be fully extracted or broken because extractive technique is improper Bad.Additionally, Chinese medicine prescription is complicated, mouthfeel difference causes patient compliance poor, it is often necessary to Oral administration, through renal metabolism, complicated Chinese medicine ingredients has increased the weight of the burden of kidney, to kidney Dirty cause damage.
Summary of the invention
For the deficiency overcoming the health food in prior art with moistening and cleaning throat effect to exist, this Bright provide a kind of have heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst the health food containing Armeniaca mume Sieb. combination Thing.By selecting suitable medical material and regulation compatibility, toxic and side effects of the present invention is little and has nourishing Effect；Use the modern technologies such as reflux, extract, decompression distillation and centrifugal spray drying, fully Efficiently extract out the effective ingredient of ingredients；Meanwhile, the present composition can utilize existing Being prepared as the dosage form such as buccal tablet, spray for general formulation technology of preparing, medicine is directly by viscous Film absorbs, it is not necessary to the metabolism through health just directly onset, greatly distribution can wave medicine Imitate and reduce Liver and kidney toxicity.
The invention provides a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb., bag Include and prepare raw material and parts by weight thereof as follows:
Armeniaca mume Sieb. 18-36 part, Radix Platycodonis 18-22 part, Herba Taraxaci 6-24 part, Fructus Crataegi 8-12 part, horsewhip Grass 10-14 part, Radix Rehmanniae 2-8 part, Periostracum Cicadae 12-20 part, Herba Menthae 4-10 part, Radix Glycyrrhizae 4-16 part, Radix Puerariae 2-4 part and Radix Polygoni Multiflori 4-12 part.
Further, the described health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb., including Prepare raw material and parts by weight thereof as follows:
27 parts of Armeniaca mume Sieb., Radix Platycodonis 20 parts, Herba Taraxaci 15 parts, Fructus Crataegi 10 parts, Herba Verbenae 12 parts, life Radix Rehmanniae 5 parts, Periostracum Cicadae 16 parts, Herba Menthae 7 parts, 10 parts of Radix Glycyrrhizae, Radix Puerariae 3 parts and Radix Polygoni Multiflori 8 parts.
Further, the described health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb., including Prepare raw material and parts by weight thereof as follows:
18 parts of Armeniaca mume Sieb., Radix Platycodonis 18 parts, Herba Taraxaci 6 parts, Fructus Crataegi 8 parts, Herba Verbenae 10 parts, the Radix Rehmanniae Yellow 2 parts, Periostracum Cicadae 12 parts, Herba Menthae 4 parts, 4 parts of Radix Glycyrrhizae, Radix Puerariae 2 parts and Radix Polygoni Multiflori 4 parts.
Further, the described health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb., including Prepare raw material and parts by weight thereof as follows:
36 parts of Armeniaca mume Sieb., Radix Platycodonis 22 parts, Herba Taraxaci 24 parts, Fructus Crataegi 12 parts, Herba Verbenae 14 parts, life Radix Rehmanniae 8 parts, Periostracum Cicadae 20 parts, Herba Menthae 10 parts, 16 parts of Radix Glycyrrhizae, Radix Puerariae 4 parts and Radix Polygoni Multiflori 12 parts.
Further, described health-care food composition is made into buccal tablet or spray.
Further, present invention also offers a kind of health care food with moistening and cleaning throat effect containing Armeniaca mume Sieb. The preparation method of product compositions, comprises the following steps:
S1, pluck fresh Armeniaca mume Sieb., dry after cleaning, add the distilled water of Armeniaca mume Sieb. weight 1-2 times, Homogenizer stirring 5～10min, arranging speed of agitator is 500-1000rpm, stands, and filters Decontamination, obtains Armeniaca mume Sieb. serosity；
S2, the ethanol solution of the Armeniaca mume Sieb. serosity addition 75-90% prepared toward S1, reflux, extract, 1-3 time, each 3～6h, united extraction liquid, stand, filter decontamination, obtain Armeniaca mume Sieb. and extract Thing, standby；
S3, take Radix Platycodonis, Herba Taraxaci, Radix Rehmanniae and Periostracum Cicadae, respectively decontamination, clean, dry Dry, it is ground into coarse powder after section, mixing, add according to the 6-12 times amount of above-mentioned coarse powder gross weight Enter the ethanol solution that volumetric concentration is 70-95%, soak 12-24h, reflux, extract, 2-4 time, 3-5h every time, filters, and retains filtering residue, merging filtrate, and decompression is distilled off ethanol, concentrates, Obtain concentrated solution A, standby；
S4, take Fructus Crataegi, Herba Verbenae, Herba Menthae, Radix Glycyrrhizae, Radix Puerariae and Radix Polygoni Multiflori, roguing respectively Matter, cleans, and dries, is ground into coarse powder after section, mixes with step S3 gained filtering residue after mixing Even, add distilled water, reflux, extract, according to the 7-9 times amount of above-mentioned coarse powder and filtering residue gross weight 3-6 hour, filter, merging filtrate, concentrate, obtain concentrated solution B, standby；
S5, the plum extract of S2 gained is merged with described concentrated solution A, B, the most mixed Even, with inlet temperature be 110-150 DEG C, leaving air temp for 70-90 DEG C be centrifuged be spray-dried, It is prepared as compositions fine powder, adds corresponding adjuvant, be prepared as health-care food composition finished product.
Further, the solid-liquid ratio extracted in described step S2 is 1:(6-20).
Further, the adjuvant added in described step S5 is selected from pH adjusting agent, sweet taste One or more in agent, excipient, correctives, lubricant and preservative, wherein, described One or more in citric acid, lactic acid, malic acid and tartaric acid of pH adjusting agent, sweet Taste agent is selected from white sugar, Mel, mannose, fructose, sucrose, aspartame, acesulfame potassium, sweet In the sugar-free sweetener that inulin, stevioside, maltose and applicable diabetics are taken one Planting or several, excipient is in xylitol, maltose, lactose, mannitol and erythritol One or more, correctives is in stevioside, citric acid, Mentholum and Oleum menthae One or more, preservative is selected from sodium benzoate and/or potassium sorbate.
According to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs and the compatibility theory of Chinese crude drug of the traditional Chinese medical science, in conjunction with the health element of modern Matter and the feature of modern pharmaceutical technology, the collocation ingredients of reasonable science, form the present invention and protect Health food compositions.Armeniaca mume Sieb. convergence spermatogenesis, astringing lung-QI and relieving cough, enhancing metabolism, relieving diarrhea with astringents；Fructus Citri tangerinae Stalk and Herba Taraxaci heat-clearing and toxic substances removing, sore-throat relieving wet one's whistle, evacuation of pus of eliminating the phlegm；Fructus Crataegi, Herba Verbenae and Radix Rehmanniae Inducing diuresis to remove edema, circulation of qi promoting dissipating blood stasis, scattered wind heat extraction；Periostracum Cicadae, Herba Menthae, Radix Puerariae and Radix Polygoni Multiflori expelling pathogenic factors from muscles move back Heat, dispelling wind-heat, removing toxicity for eliminating carbuncles, invigorating the spleen and replenishing QI；Radix Glycyrrhizae can heat-clearing and toxic substances removing, expelling phlegm for arresting cough, Again can coordinating the actions of various ingredients in a prescription, relax cold and cool property.Each component compatibility is reasonable, makes a distinction between the important and the lesser one, stresses to adjust Reason, coordinate mutually and, play effect of replenishing YIN and removing heat, dispelling phlegm and relieving sore-throat, removing toxicity for eliminating carbuncles altogether.
Compared with prior art, the present invention has a following technical advantage:
1, health-care food composition of the present invention can be not only used for throat health care, prevention laryngopharyngeal diseases, Can effectively alleviate again and treat pharyngitis disease.
2, health-care food composition of the present invention is made up of Armeniaca mume Sieb. and pure natural Chinese herbal medicine, stresses to adjust Reason, has heat-clearing and toxic substances removing, effect of promoting the production of body fluid to quench thirst/nourishing, and toxic and side effects is little.
3, health-care food composition component of the present invention is simple, is more beneficial for quality control；Produce Technique is simple and environmentally-friendly and low cost, is suitable for industrialized great production.
Detailed description of the invention
It will be understood by those skilled in the art that technology disclosed in following example represents the present invention The technology playing good action in the practice of the invention that people finds.But, disclosed Specific embodiments can be made many changes, and still obtain same or analogous result, Without departing from the spirit and scope of the present invention.
Embodiment 1, a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb.
The embodiment of the present invention 1 health-care food composition is by the raw material preparation of following parts by weight Become: 27 parts of Armeniaca mume Sieb., Radix Platycodonis 20 parts, Herba Taraxaci 15 parts, Fructus Crataegi 10 parts, Herba Verbenae 12 parts, life Radix Rehmanniae 5 parts, Periostracum Cicadae 16 parts, Herba Menthae 7 parts, 10 parts of Radix Glycyrrhizae, Radix Puerariae 3 parts and Radix Polygoni Multiflori 8 parts.
Preparation method is as follows:
S1, pluck fresh Armeniaca mume Sieb., dry after cleaning, add the distilled water of Armeniaca mume Sieb. weight 2 times, Homogenizer stirring 5min, arranging speed of agitator is 500rpm, stands, and filters decontamination, Obtain Armeniaca mume Sieb. serosity；
S2, the ethanol solution of the Armeniaca mume Sieb. serosity addition 75% prepared toward S1 by solid-liquid ratio 1:9, Reflux, extract, 2 times, each 4h, united extraction liquid, stand, filter decontamination, obtain Armeniaca mume Sieb. Extract, standby；
S3, take Radix Platycodonis, Herba Taraxaci, Radix Rehmanniae and Periostracum Cicadae, respectively decontamination, clean, dry Dry, it is ground into coarse powder after section, mixing, add according to 8 times amount of above-mentioned coarse powder gross weight Volumetric concentration is the ethanol solution of 75%, immersion 12h, reflux, extract, 3 times, each 3h, Filtering, retain filtering residue, merging filtrate, decompression is distilled off ethanol, concentrates, obtains concentrated solution A, Standby；
S4, take Fructus Crataegi, Herba Verbenae, Herba Menthae, Radix Glycyrrhizae, Radix Puerariae and Radix Polygoni Multiflori, roguing respectively Matter, cleans, and dries, is ground into coarse powder after section, mixes with step S3 gained filtering residue after mixing Even, add distilled water, reflux, extract, 5 according to 8 times amount of above-mentioned coarse powder and filtering residue gross weight Hour, filter, merging filtrate, concentrate, obtain concentrated solution B, standby；
S5, the plum extract of S2 gained is merged with described concentrated solution A, B, the most mixed Even, with inlet temperature be 110 DEG C, leaving air temp be 80 DEG C and be centrifuged being spray-dried, system Standby one-tenth compositions fine powder, adds lactic acid, maltose, citric acid, fructose and lactic acid, pressure Sheet, is prepared as buccal tablet.
Embodiment 2, a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb.
The embodiment of the present invention 2 health-care food composition is by the raw material preparation of following parts by weight Become: 18 parts of Armeniaca mume Sieb., Radix Platycodonis 18 parts, Herba Taraxaci 6 parts, Fructus Crataegi 8 parts, Herba Verbenae 10 parts, the Radix Rehmanniae Yellow 2 parts, Periostracum Cicadae 12 parts, Herba Menthae 4 parts, 4 parts of Radix Glycyrrhizae, Radix Puerariae 2 parts and Radix Polygoni Multiflori 4 parts.
Preparation method reference example 1.
Embodiment 3, a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb.
The embodiment of the present invention 3 health-care food composition is by the raw material preparation of following parts by weight Become: 36 parts of Armeniaca mume Sieb., Radix Platycodonis 22 parts, Herba Taraxaci 24 parts, Fructus Crataegi 12 parts, Herba Verbenae 14 Part, Radix Rehmanniae 8 parts, Periostracum Cicadae 20 parts, Herba Menthae 10 parts, 16 parts of Radix Glycyrrhizae, Radix Puerariae 4 parts and Radix Polygoni Multiflori 12 parts.
Preparation method reference example 1.
Comparative example 1, a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb.
Comparative example 1 health-care food composition of the present invention is by the raw material preparation of following parts by weight Become: 27 parts of Armeniaca mume Sieb., Radix Platycodonis 20 parts, Herba Taraxaci 15 parts, Fructus Crataegi 10 parts, Herba Verbenae 12 parts, life Radix Rehmanniae 5 parts, Periostracum Cicadae 16 parts, Herba Menthae 7 parts, 10 parts of Radix Glycyrrhizae, Radix Scrophulariae 3 parts and Radix Polygoni Multiflori 8 parts.
Preparation method reference example 1.
Comparative example 1 is with the difference of embodiment 1, and Radix Puerariae is replaced with Radix Scrophulariae.
Comparative example 2, a kind of health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb.
Comparative example 2 health-care food composition of the present invention is by the raw material preparation of following parts by weight Become: 27 parts of Armeniaca mume Sieb., Radix Platycodonis 25 parts, Herba Taraxaci 15 parts, Fructus Crataegi 10 parts, Herba Verbenae 12 parts, life Radix Rehmanniae 5 parts, Periostracum Cicadae 16 parts, Herba Menthae 7 parts, Radix Puerariae 8 parts and Radix Polygoni Multiflori 8 parts.
Preparation method reference example 1.
Comparative example 2 is with the difference of embodiment 1, eliminates Radix Glycyrrhizae, adds Radix Platycodonis and Pueraria lobota The parts by weight of root.
Test example one, the rat toes swelling test of health-care food composition of the present invention
1, subjects: choosing 80 SPF level Wistar kind female ablactation rats, body weight is 250g ± 30g, is provided by Ji'nan University's Experimental Animal Center.
2, test material: the embodiment of the present invention 1, embodiment 2, embodiment 3, comparative example 1 and The moistening and cleaning throat buccal tablet of comparative example 2 preparation, adds the water dissolution of 2 times of quality；Positive control drug is dragon Rising oral liquid for removing intense heat from throat, is purchased from Putian, fujian Province Long Sheng group company, the strong word G20040033 of state's food.
3, test method: 80 rats are randomly divided into 8 groups, respectively model group, Long Sheng Board oral liquid for removing intense heat from throat group, embodiment 1-3 group, comparative example 1-2 group and blank group, often group 10, the dosage of each group is as follows:
Positive drug group: the imperial rising oral liquid for removing intense heat from throat of gavage 0.5g/kg；
Embodiment 1-3 group: what respectively prepared by gavage 40ml/kg embodiment 1-3 has moistening and cleaning throat effect Health-care food composition buccal tablet aqueous solution；
Comparative example 1-2 group: what respectively prepared by gavage 40ml/kg comparative example 1-2 has moistening and cleaning throat effect Health-care food composition buccal tablet aqueous solution；
Model group: the isopyknic normal saline of gavage；
Blank group: the isopyknic normal saline of gavage；
Before test, health-care food composition buccal tablet distilled water of the present invention is dissolved, be configured to examination Test desired concn.Each group rat gastric infusion respectively, model group gives the distilled water of equivalent, often It 1 time, continuous 30 days.
4, modeling
Rat Right metapedes plantar subcutaneous injection 1% carrageenin 0.1ml/ after last is administered 60min Only.Within 3,9 hours after causing inflammation, measuring foot sole of the foot portion thickness respectively, same position is measured 3 times, Take its meansigma methods.It is respectively compared the difference condition of each dosage group different time points foot sole of the foot portion thickness (joining from Ministry of Public Health health food inspection in 2003 and assessment technique specification).
5, result of the test:
Table 1 rat toes swelling situation
Note: compare with model group,**P < 0.01,*P<0.05；Compare with positive drug group,△△P < 0.01,△P<0.05.As seen from the above table, embodiment 1～3 groups 3 hours and 9 little rear rat toes swelling Rate is all remarkably decreased, and has significant difference (P < 0.01 or P < 0.05) compared with model group； Comparative example 1～2 groups are compared with the embodiment of the present invention 1～3 groups, and its effect all decreases, and this says Bright, the embodiment of the present invention 1～3 health-care food composition can significantly improve the inflammation situation of mice.
Owing to describing the present invention by above preferred embodiment, the present invention spirit and / or scope in, any replacement/for the present invention or combination implement the present invention, for ability Will be apparent from for the technical staff in territory, and be included among the present invention.

Claims (10)

1. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb., it is characterised in that include as follows Prepare raw material and parts by weight thereof:
Armeniaca mume Sieb. 18-36 part, Radix Platycodonis 18-22 part, Herba Taraxaci 6-24 part, Fructus Crataegi 8-12 part, Herba Verbenae 10-14 part, Radix Rehmanniae 2-8 part, Periostracum Cicadae 12-20 part, Herba Menthae 4-10 part, Radix Glycyrrhizae 4-16 part, Radix Puerariae 2-4 part and Radix Polygoni Multiflori 4-12 Part.
2. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. as claimed in claim 1, its feature It is, including preparing raw material and parts by weight thereof as follows:
27 parts of Armeniaca mume Sieb., Radix Platycodonis 20 parts, Herba Taraxaci 15 parts, Fructus Crataegi 10 parts, Herba Verbenae 12 parts, Radix Rehmanniae 5 parts, Periostracum Cicadae 16 parts, Herba Menthae 7 parts, 10 parts of Radix Glycyrrhizae, Radix Puerariae 3 parts and Radix Polygoni Multiflori 8 parts.
3. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. as claimed in claim 1, its feature It is, including preparing raw material and parts by weight thereof as follows:
18 parts of Armeniaca mume Sieb., Radix Platycodonis 18 parts, Herba Taraxaci 6 parts, Fructus Crataegi 8 parts, Herba Verbenae 10 parts, Radix Rehmanniae 2 parts, Cicadae Slough off 12 parts, Herba Menthae 4 parts, 4 parts of Radix Glycyrrhizae, Radix Puerariae 2 parts and Radix Polygoni Multiflori 4 parts.
4. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. as claimed in claim 1, its feature It is, including preparing raw material and parts by weight thereof as follows:
36 parts of Armeniaca mume Sieb., Radix Platycodonis 22 parts, Herba Taraxaci 24 parts, Fructus Crataegi 12 parts, Herba Verbenae 14 parts, Radix Rehmanniae 8 parts, Periostracum Cicadae 20 parts, Herba Menthae 10 parts, 16 parts of Radix Glycyrrhizae, Radix Puerariae 4 parts and Radix Polygoni Multiflori 12 parts.
5. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. as described in claim 1-4 is arbitrary, its Being characterised by, described health-care food composition is made into buccal tablet or spray.
6. the health-care food composition with moistening and cleaning throat effect containing Armeniaca mume Sieb. as described in claim 1-4 is arbitrary, its Being characterised by, described health-care food composition is prepared by following steps:
S1, pluck fresh Armeniaca mume Sieb., dry after cleaning, add the distilled water of Armeniaca mume Sieb. weight 1-2 times, high-speed stirred Machine stirring 5～10min, arranging speed of agitator is 500-1000rpm, stands, and filters decontamination, obtains Armeniaca mume Sieb. Serosity；
S2, the ethanol solution of the Armeniaca mume Sieb. serosity addition 75-90% prepared toward S1, reflux, extract, 1-3 time, often Secondary 3～6h, united extraction liquid, stand, filter decontamination, obtain plum extract, standby；
S3, take Radix Platycodonis, Herba Taraxaci, Radix Rehmanniae and Periostracum Cicadae, respectively decontamination, clean, dry, after section Being ground into coarse powder, mixing, adding volumetric concentration according to the 6-12 times amount of above-mentioned coarse powder gross weight is 70-95% Ethanol solution, soak 12-24h, reflux, extract, 2-4 time, each 3-5h, filter, retain filtering residue, conjunction And filtrate, decompression is distilled off ethanol, concentrates, obtains concentrated solution A, standby；
S4, take Fructus Crataegi, Herba Verbenae, Herba Menthae, Radix Glycyrrhizae, Radix Puerariae and Radix Polygoni Multiflori, respectively decontamination, clean, Dry, after section, be ground into coarse powder, mix, according to above-mentioned coarse powder and filter with step S3 gained filtering residue after mixing The 7-9 times amount of slag gross weight adds distilled water, reflux, extract, 3-6 hour, filters, merging filtrate, concentrates, Obtain concentrated solution B, standby；
S5, the plum extract of S2 gained is merged with described concentrated solution A, B, fully mix, with air intake Temperature is 110-150 DEG C, leaving air temp is 70-90 DEG C and is centrifuged being spray-dried, and is prepared as compositions fine powder, Add corresponding adjuvant, be prepared as health-care food composition finished product.
7. health-care food composition as claimed in claim 6, it is characterised in that extract in described step S2 Solid-liquid ratio be 1:(6-20).
8. health-care food composition as claimed in claim 6, it is characterised in that institute in described step S5 State adjuvant one in pH adjusting agent, sweeting agent, excipient, correctives, lubricant and preservative or Several, wherein, described pH adjusting agent one in citric acid, lactic acid, malic acid and tartaric acid or Several, described sweeting agent selected from white sugar, Mel, mannose, fructose, sucrose, aspartame, acesulfame potassium, One or several in the sugar-free sweetener that stevioside, stevioside, maltose and applicable diabetics are taken Kind, described excipient one or several in xylitol, maltose, lactose, mannitol and erythritol Kind, one or more in stevioside, citric acid, Mentholum and Oleum menthae of described correctives, institute State preservative selected from sodium benzoate and/or potassium sorbate.
9. the preparation method of the health-care food composition containing Armeniaca mume Sieb. as described in claim 1-8 is arbitrary, it is special Levy and be, comprise the following steps:
S1, pluck fresh Armeniaca mume Sieb., dry after cleaning, add the distilled water of Armeniaca mume Sieb. weight 1-2 times, high-speed stirred Machine stirring 5～10min, arranging speed of agitator is 500-1000rpm, stands, and filters decontamination, obtains Armeniaca mume Sieb. Serosity；
S2, the ethanol solution of the Armeniaca mume Sieb. serosity addition 75-90% prepared toward S1, reflux, extract, 1-3 time, often Secondary 3～6h, united extraction liquid, stand, filter decontamination, obtain plum extract, standby；
S3, take Radix Platycodonis, Herba Taraxaci, Radix Rehmanniae and Periostracum Cicadae, respectively decontamination, clean, dry, after section Being ground into coarse powder, mixing, adding volumetric concentration according to the 6-12 times amount of above-mentioned coarse powder gross weight is 70-95% Ethanol solution, soak 12-24h, reflux, extract, 2-4 time, each 3-5h, filter, retain filtering residue, conjunction And filtrate, decompression is distilled off ethanol, concentrates, obtains concentrated solution A, standby；
S4, take Fructus Crataegi, Herba Verbenae, Herba Menthae, Radix Glycyrrhizae, Radix Puerariae and Radix Polygoni Multiflori, respectively decontamination, clean, Dry, after section, be ground into coarse powder, mix, according to above-mentioned coarse powder and filter with step S3 gained filtering residue after mixing The 7-9 times amount of slag gross weight adds distilled water, reflux, extract, 3-6 hour, filters, merging filtrate, concentrates, Obtain concentrated solution B, standby；
S5, the plum extract of S2 gained is merged with described concentrated solution A, B, fully mix, with air intake Temperature is 110-150 DEG C, leaving air temp is 70-90 DEG C and is centrifuged being spray-dried, and is prepared as compositions fine powder, Add corresponding adjuvant, be prepared as health-care food composition finished product.
10. the preparation method of the health-care food composition containing Armeniaca mume Sieb. as claimed in claim 9, it is characterised in that The solid-liquid ratio extracted in described step S2 is 1:(6-20).
CN201610393297.1A 2016-06-06 2016-06-06 Green plum-containing healthcare food composition with throat clearing effect and preparation method thereof Pending CN105942523A (en)

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Application publication date: 20160921