CN105919922A - Cosmetic composition including an acanthus extract of ceriporia lacerata and cosmetics using the same - Google Patents
Cosmetic composition including an acanthus extract of ceriporia lacerata and cosmetics using the same Download PDFInfo
- Publication number
- CN105919922A CN105919922A CN201510792535.1A CN201510792535A CN105919922A CN 105919922 A CN105919922 A CN 105919922A CN 201510792535 A CN201510792535 A CN 201510792535A CN 105919922 A CN105919922 A CN 105919922A
- Authority
- CN
- China
- Prior art keywords
- extract
- cosmetics
- cosmetic material
- wax
- tear wax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a cosmetic composition including an extract of Ceriporia lacerata, and cosmetics using the cosmetic composition. More specifically, the present invention relates to a cosmetic composition produced by using Ceriporia lacerata extract alone or by adding an extract of ginseng and an extract of grape seed to the Ceriporia lacerata extract which is an extract of mushroom, and to cosmetics produced by containing a predetermined amount of the cosmetic compositions.
Description
Technical field
The present invention is about the cosmetic material containing tear wax linteus extract and to use this raw material system
The cosmetics become, more specifically, only use tear wax pore fungi (Ceriporia lacerata, CL)
Extract or tear wax linteus extract in add mushroom extract, ginseng fruit extracts, Portugal
The cosmetic material that grape seed extract is made, and the above-mentioned cosmetic material manufacture containing certain deal
Cosmetics.
The cosmetic material so manufactured and the cosmetics containing above-mentioned cosmetic material not only have U.S.
In vain, antioxidation, minimizing stimulation, moisture-keeping efficacy, also have increase skin elasticity, the merit of skin regeneration
Effect, belongs to high performance cosmetic.
Background technology
Industry development is rapid, and the environmental pollution and the numerous and diverse city life that cause are raw to the consumption of modern
The pattern of living creates tremendous influence.One of change of people's life pattern is just embodied in hope and promotes life
In health care's trend of quality.
This health care's trend is to trend towards Organic food and naturalistic phenomenon.Produce at cosmetics
Industry, also drops to minimum by the use of synthetic source, by using natural material, advocates protection skin and changes
The naturalism cosmetics of kind skin quality, natural material extract cosmetic etc. constantly exposes, and is consumed
Person pursues, and popularity prevails.
The present invention is to cater to fashion trend, provides the consumer with use high-performance natural material manufacture
Cosmetic material and use the cosmetics that this cosmetic material manufactures.
It should be noted that the tear wax pore fungi that the invention provides prevention diabetes function
(Ceriporia lacerata) extract is the cosmetic material of primary raw material, and containing certain deal
The cosmetics of above-mentioned cosmetic material.
Above-mentioned tear wax pore fungi (Ceriporia lacerata) is saprophytic polypor on Oak Tree or Pinus densiflora
Section mushroom.Tear wax pore fungi is in China, and Japan and Korea S are used for therapeutic treatment always, and due to it
There is the effect decomposing lignin, be used as natural biology cleanser.
[prior art document]
[patent documentation]
(patent documentation 1) Republic of Korea registered patent 10-0206538 (registration date
1999.04.08)
(patent documentation 2) Republic of Korea registered patent 10-0863890 (registration date
2008.10.09)
(patent documentation 3) Republic of Korea registered patent 10-2011-0126520 (publication date
2011.11.23)
(patent documentation 4) Republic of Korea registered patent 10-1245730 (registration date
2013.03.14)
(patent documentation 5) Republic of Korea registered patent 10-1402193 (registration date
2014.05.26)
Summary of the invention
[problem to be solved]
It is an object of the invention to be used alone Polyporaceae mushroom-tear wax pore fungi (Ceriporia
Lacerata) extract, or provide interpolation ginseng berry in above-mentioned tear wax linteus extract to extract
The cosmetic material that thing, Semen Vitis viniferae extract are made.
And the cosmetics providing the above-mentioned cosmetic material containing certain deal to manufacture, there is whitening merit
Effect, antioxidation, without skin irritation, moistening effect is good, belongs to high performance cosmetic.
[problem solution]
For reaching above-mentioned purpose, the present invention provides the cosmetic material using tear wax linteus extract,
Above-mentioned cosmetic material tears wax linteus extract for being used alone, or above-mentioned tear wax pore fungi
The raw material that in extract, interpolation ginseng fruit extracts, Semen Vitis viniferae extract are made.And, the present invention
There is provided and comprise the above-mentioned cosmetic material accounting for gross weight 1～30wt%, containing tear wax linteus extract
Cosmetics.
[effect of invention]
The present invention is individually with tear wax linteus extract as raw material, or in order to improve effect, is also added with
Ginseng fruit extracts, Semen Vitis viniferae extract, make cosmetic material and the change using this raw material to manufacture
Cosmetic, has whitening, antioxidation, minimizing stimulation, moistening effect, also gives skin elasticity,
Help the function of skin regeneration, belong to high-quality, high performance cosmetic.
Detailed description of the invention
The following is the more specifically content of relevant above-mentioned technological maheup.
As it has been described above, the cosmetic material in the present invention is used alone tear wax linteus extract,
Or in above-mentioned tear wax linteus extract, add ginseng fruit extracts, Semen Vitis viniferae extract system
Become cosmetic material.
Tear wax linteus extract in above-mentioned cosmetic material has suppression cytotoxic effect, above-mentioned
Ginseng fruit extracts has anti-inflammatory, anti-oxidation efficacy, and above-mentioned Semen Vitis viniferae extract has contraction hair
Hole, improves wrinkle, keeps the skin wet and increases effect of skin elasticity.
The first mode of operation is, cosmetic material is used alone tear wax pore fungi, former as cosmetics
Material, concrete mode is, use drinking water washing tear wax pore fungi 2～3 times, then utilizes lyophilization
Machine is dried, and freeze-dried tear wax pore fungi is put in pulverizer and pulverizes, then warp
80～120mesh strainer filterings go out powder and be positioned over-15～the environment of-25 DEG C in freezing keeping, will
The tear wax linters powder of freezing keeping joins in 80% methanol solution (MeOH), according to 1:20～30
Weight ratio add, the extract in normal temperature environment, after completing extraction for 3～5 days, to extraction
Carry out first round filtration, under conditions of 3000 × g, carry out 2～4 minutes center of circle lock out operation, only
Extract supernatant liquid, the tear wax linteus extract natural material basis gone out with 0.1～0.3 μm strainer filtering
Body is as cosmetic material.
The cosmetic material of the second mode of operation is to add ginseng pulp in tear wax linteus extract
Berry extract is made.
Concrete mode, is by above-mentioned tear wax linteus extract 1～99wt% and ginseng fruit extracts
1～99wt% is mixed and made into natural material, uses as cosmetic material.
The most above-mentioned ginseng fruit extracts is to use drinking water washing ginseng berry (Panax ginseng)
2～3 times, it is then placed in freezer dryer being dried, by cryodesiccated ginseng berry dried object
Middle addition, in ethanol solution, is added according to the weight ratio of 1:2～4, after circulation extraction, through filtering also
Concentrating under reduced pressure in the environment of 35～45 DEG C, uses the product obtained.
The third mode of operation is, adds Portugal in tear wax linteus extract and ginseng fruit extracts
Grape seed extract, makes cosmetic material.Concrete mode is, by above-mentioned tear wax linteus extract
1～98wt%, ginseng fruit extracts 1～98wt%, Semen Vitis viniferae extract 1～30wt% is mixed and made into sky
So material, uses as cosmetic material.
Now, Semen Vitis viniferae extract is the methanol adding its 10 times amount in 300g Semen Vitis viniferae powder
(MeOH) solution, after using vibrosieve to carry out 3 extractions repeatedly of each 6 hours, with filter paper
After (Watman No.2) filters extracting solution, the product that recycling Rotary Evaporators concentrating under reduced pressure obtains.
The present invention is to be made according to certain ratio cosmetic material mentioned above.
Concrete mode is, will tear wax linteus extract 1～99wt% and ginseng fruit extracts
1～99wt% carries out being mixed 100wt% cosmetic material, when manufacturing cosmetics, is taken out
1～30wt% adds in cosmetics.
And, tear wax linteus extract 1～98wt%, ginseng fruit extracts 1～98wt%, and
Semen Vitis viniferae extract 1～30wt% is mixed and made into 100wt% cosmetic material, when manufacturing cosmetics, from
Middle taking-up 1～30wt% is added in cosmetics.
The present invention is to add in cosmetics by above-mentioned cosmetic material according to the 1～30wt% of gross weight,
Make cosmetics.
Above-mentioned cosmetic composition is roughly divided into aqueous (Aqueous) and oiliness (Oil phaes).Water composition
Water soluble, oil components dissolves in oil.Represent water composition is the glycerol used as wetting agent,
Oil components has quintessence oil and pomade.They are widely used in cosmetics, cosmetics by water composition with
Oil components is mixed according to proper proportion.Comprise Purified Water, oiliness raw material, surfactant,
Wetting agent, spice, functional raw material.
Above-mentioned Purified Water accounts for more than the 70% of cosmetics, simply manufactures the basis one-tenth of cosmetics in the past
Point, now application volcanic rock water, bamboo extracting solution, glacial water, flowers water etc., quilt recently
It is referred to as functional cosmetics raw material.
The suppression moisture evaporation of above-mentioned oiliness raw material, prevents from being dried, makes skin emolliency, use sense for promoting
With the addition of plants essential oil；Animal quintessence oil；Mineral quintessence oil；Isopropyl myristate, octyl dodecanol
The synthesis quintessence oil such as myristinate；The waxs such as Apis cerana Fabricius, candelilla wax, jojoba quintessence oil；Palmityl alcohol,
The higher alcohols such as lauryl alcohol.
The chemical structure characteristic of above-mentioned surfactant is to contain hydrophilic group and lipophilic group in molecule simultaneously.
Surfactant one end is ionic groups, is dissolved in water, and other end is carbohydrate structure group,
It is dissolved in oil.
If skin itself is containing sufficient moisture, skin may appear to the most healthy flexible, above-mentioned guarantor
Humectant pins our skin or the moisture of hair, prevents from being dried.The wetting agent used in cosmetics is sweet
The polyhydric alcohol such as oil, propylene glycol, Polyethylene Glycol；Containing sodium lactate, pyrrolidone sodium carboxylate, hyalomitome
The nature moisturizing factor such as acid sodium.
Above-mentioned coloring agent is formulated in cosmetics, presents color and luster, has covering power, uv reflectance.
If foundation emulsion or eye shadow color make-up product, have the effect giving its color and luster, in basic cosmetics in order to
Presenting visual effect, portioned product is also using.Pigment has carcinogen, may cause dermatitis
Disease etc., harmful topic discusses warmly constantly, represent composition have tar system pigment, natural pigment,
Inorganic pigment etc..
Above-mentioned polymer substance is the compound that molecular weight is huge.According to purposes, part is used as thickening
Agent, film former, wetting agent, surfactant.Representative species is oblonga seed glue (Quince seed gum),
Xanthan gum (Xanthan gum), carbopol etc..
Above-mentioned spice makes cosmetics give out the fragrance of smelling good, can promote the value of cosmetics, it is also possible to
Eliminate the taste that raw material is special.It is recently introduced the champignon therapy being referred to as Aromatherapy, is changing
Cosmetic is added herbaceous plant, can help to be absorbed in the stable essence of modern of pressure and the puzzlement of various disease
God, body and mind of releiving.But spice is according to personal like, may bring side effect as being not suitable with, therefore,
Cosmetic formulations to consider suitably to use ratio.
But, have about tear wax pore fungi at present and prevent effect of diabetes and record not to be demonstrate,proved
Real.The most in our current research, with rat insulin cell (INS-1) as subjects, by throwing something and feeding
Effect is also for dexamethasone (Dex) research cytotoxicity (survival rate reduces, cell death inducement)
Investigation record, also to cultivate tear wax pore fungi obtain extract (Ceriporia lacerata extract,
CLE), its protected effect Cytotoxic for induced by dexamethasone INS-1 illustrate record.Additionally
With Wistar rat as subjects, dexamethasone of throwing something and feeding (Dex), study steroid hormone glycosuria
Sick induced effectiveness, and confirm the inhibition tearing wax linteus extract for Dex induced diabetes,
And confirm relevant record.
Preservative: it may happen that cosmetics are polluted by microorganism when making to apply some make up, occurs rotten
Situation.If rotten possible initiation safety problem occur in cosmetics, microorganism is also possible to cause skin to go out
The safety problems such as existing disease.In cosmetics, it is single more anti-than using that Determination of Preservatives mixes use
Rotten agent is effective, although be used in mixed way effective, but human body can be caused the peace of side effect by preservative
Full problem is controversial.Therefore, cosmetic formulations must consider content carefully.Representing composition is benzene potassium
Esters of gallic acid, imidazolidinyl urea, phenoxyethanol etc..
Below for the present invention about cosmetic material and the system of the cosmetics using above-mentioned cosmetic material
Make technology, illustrated by operational instances.
[operational instances 1]
It is used alone the cosmetic material that tear wax linteus extract manufactures
In this operational instances 1, use tear wax linteus extract itself as cosmetic material.
To this end, use drinking water washing tear wax pore fungi 2～3 times, then lyophilization.Now use
Refrigerating chamber (VLT 1450-3-D-14, Thermo Electron Corp., Asheville, NC, USA) exists
Lyophilization 24 hours under conditions of-45 DEG C, re-use freezer dryer (PPU-1100, Tokyo
Rikakikai Co., Japan) under conditions of 8.5Pa, it is dried to moisture and no longer occurs being changed to
Only.
After lyophilization completes, cryodesiccated tear wax pore fungi is put in pulverizer and carries out the first round
Pulverize, go out powder by the strainer filtering of 100mesh the most again, and use.
Above-mentioned powder is freezing keeping under conditions of being positioned over-20 DEG C, uses during extraction.
It follows that in methanol (MeOH) solution that will add to 80% in tear wax pore fungi, according to 1:20
Weight ratio add, in normal temperature environment extract 5 days.
The extracting solution of extraction filtered through the first round, 3, carried out 3 minutes centers of circle under conditions of 000 × g
Separate, the most only extract supernatant liquid, carry out filtration treatment with 0.3 μm filter screen.
The tear wax linteus extract good by this mode filtration treatment uses as cosmetic material.
[operational instances 2]
Add, in tear wax linteus extract, the cosmetic material that ginseng fruit extracts is made
Operational instances 2 is, in the tear wax linteus extract manufactured in operation 1, according to a definite proportion
Example adds the cosmetic material that ginseng fruit extracts is made.
Above-mentioned ginseng berry (Panax ginseng) extract is, uses drinking water washing ginseng berry 2～3
Secondary, then use freezer dryer to be dried, then ginseng berry dried object good for lyophilization is added
Add in ethanol solution, add according to the weight ratio of 1:2, after circulation extraction, filter, then put
Be placed under the environmental condition of 40 DEG C, concentrating under reduced pressure, it is thus achieved that product can use.
The ginseng fruit extracts utilizing this mode to obtain is mixed with tear wax linteus extract
Cosmetic material, now, mixed proportion is, tears wax linteus extract: ginseng fruit extracts is
80:20。
[operational instances 3]
In the tear wax linteus extract mixture with ginseng fruit extracts, add Semen Vitis viniferae and extract
Thing makes cosmetic material.
Operational instances 3 is, at tear wax pore fungi and the ginseng berry of operational instances 2 of operational instances 1
In extract, add according to a certain percentage after Semen Vitis viniferae extract makes cosmetic material and re-use.
Above-mentioned Semen Vitis viniferae extract is, adds its 10 times of deals in Semen Vitis viniferae powder 300g
MeOH solution, uses vibrating sieving machine to carry out 3 extractions repeatedly of each 6 hours, passes through
Filter paper (Watman No.2) filters, use Rotary Evaporators concentrating under reduced pressure process, it is thus achieved that product
Thing can use.
Now, the ratio of making is, tear wax linteus extract: ginseng fruit extracts: Semen Vitis viniferae carries
The weight ratio taking thing is 70:20:10.
[operational instances 4]
Use the cosmetics that the cosmetic material of operational instances 1 is made
The cosmetic material 20wt% of operational instances 1；Lipophile glyceryl monostearate 2.5wt%；
Stearyl alcohol 2.0wt%；Stearic acid 2.2wt%；Apis cerana Fabricius 1.0wt%；Stearate 1.5wt%；Dehydration
Sorbitol monostearate 0.6wt%；Hydrogenated vegetable oil 1.0wt%；Squalane 3.0wt%；Mineral oil
5.5wt%；Three isooctyl acid glyceride 5.5wt%；Dimethicone 1.0wt%；Sodium magnesium silicate 0.1wt%；
Glycerol 5.5wt%；Glycine betaine 3.0wt%；Triethanolamine 1.0wt%；Hyaluronic acid sodium 4.0wt%；Anti-
Rotten agent, spice, pigment 0.01wt%；The nutrition facial cream that Purified Water 40.59wt% is mixed.
[operational instances 5]
Use the cosmetics that the cosmetic material of operational instances 2 is made
According to operational instances 4, use identical component, manufacture nutrition facial cream according to same ratio, in choosing
Select cosmetic material aspect, use the cosmetic material made in operational instances 2.
[operational instances 6]
Use the cosmetics that the cosmetic material of operational instances 3 is made
According to operational instances 5, use identical component, manufacture nutrition facial cream by same ratio, selecting
Cosmetic material aspect, uses the cosmetic material made in operational instances 3.
[comparison example 1]
Comparison example 1 is the nutrition facial cream of the cosmetic material not comprising the present invention, and lipophile list is stearic
Acid glyceride 3.5wt%；Stearyl alcohol 4.0wt%；Stearic acid 3.2wt%；Apis cerana Fabricius 2.0wt%；Stearic
Acid esters 2.5wt%；Sorbitan monostearate 1.6wt%；Hydrogenated vegetable oil 2.0wt%；Spiny dogfish
Alkane 4.0wt%；Mineral oil 5.5wt%；Three isooctyl acid glyceride 5.5wt%；Dimethicone 1.0wt%；
Sodium magnesium silicate 1.1wt%；Glycerol 6.5wt%；Glycine betaine 4.0wt%；Triethanolamine 3.0wt%；Glass
Monosodium urate 5.0wt% preservative, spice, pigment 0.01wt%；Purified Water 45.59wt% is mixed
Nutrition facial cream.
[test examples 1]
The whitening effect of the cosmetics made in aforesaid operations example 4 to 6 and comparison example 1
The cosmetics test portion of operational instances 4 to 6 and comparison example 1 is diluted in 50% dimethyl sulfoxide
(DMSO), in solution, respectively take cosmetics test portion 50 μ l, in above-mentioned each test portion, then add 0.1M
Phosphate buffer 450 μ l, chromium propylhomoserin enzyme (sigma) 50 μ l.
In mixed solution, add 1.5mM tryptophan (sigma) solution 60 μ l, stirred through 10 seconds
After mixing, in the environment of being positioned over 40 DEG C 20 minutes, under conditions of 490nm, contrast with arbutin,
Measure absorbance.
The result measuring whitening effect under the conditions of 40 DEG C is, operational instances 4 is 20.73%, operation
Example 5 is 25.25%, and operational instances 6 is 24.94%, and the measurement result of comparison example 1 is 13.19%,
Measurement result confirms, the whitening effect of operational instances 5 is best.
[test examples 2]
The antioxidant activity of the cosmetics made in aforesaid operations example 4 to 6 and comparison example 1
Cosmetics test portion in operational instances 4 to 6 and comparison example 1 is diluted in 50% dimethyl sub-
In sulfone (DMSO) solution, above-mentioned cosmetics test portion adds 10mM
DPPH (1,1-diphenyl-2-picrylhydrazyl) solution 250 μ l, after 10 seconds stir, adds
Enter 1mL distilled water, place 40 minutes under conditions of 40 DEG C, under conditions of 517nm, with
Comparison example compares, and measures absorbance.
Under conditions of 40 DEG C, the result measuring antioxidant activity is that operational instances 4 is 50.15%,
Operational instances 5 is 50.25%, and operational instances 6 is 49.36%, and the measurement result of comparison example 1 is
12.19%, measurement result confirms, the antioxidant effect of operational instances 5 is best.
[test examples 3]
The skin irritation degree of the cosmetics made in aforesaid operations example 4 to 6 and comparison example 1
The cosmetics made in aforesaid operations example 4 to 6 and comparison example 1, for understanding its skin thorn
Sharp degree has carried out skin test.
In order to carry out skin test, picking adult men and women and have 40 people altogether, age level is 25～55 years old,
Divide by sex, man 15 people, Ms 25 people.
Every 10 people of testee one group, totally 4 groups, first group of cosmetics using operational instances 4,
Second group of cosmetics using operational instances 5, the 3rd group of cosmetics using operational instances 6, the 4th
Group uses the cosmetics of comparison example 1, in upper arm, cosmetic applying is carried out patch test, through 1
Individual hour, detected by an unaided eye dermoreaction for the first time, and through 24 hours, second time was with the naked eye seen
Examine, and by logging in lower list 1.
[table 1]
Skin irritation degree
| Classification | Average mark |
| Operational instances 4 | ○ |
| Operational instances 5 | ○ |
| Operational instances 6 | ○ |
| Comparison example 1 | ○ |
(zero: skin is unchanged, △: slight erythema occurs, x: bright scarlet speckle occurs)
The result of summary table 1, operational instances 4 to 6 and comparison example 1, change of skin does not all occur,
Non-stimulated to skin, can use safely.
[test examples 4]
The moistening effect of the cosmetics that aforesaid operations example 4 to 6 and comparison example 1 are made
For confirming aforesaid operations example 4 to 6 and the moistening effect of comparison example 1, select adult men and women
Altogether 40 people, age level is 25～55 years old, divides by sex, man 15 people, Ms 25 people.
Every 10 people of testee one group, totally 4 groups, first group of cosmetics using operational instances 4,
Second group of cosmetics using operational instances 5, the 3rd group of cosmetics using operational instances 6, the 4th
Group uses the cosmetics of comparison example 1, uses 5 algoscopy assessments, and result is recorded in table 6
In.
[table 2]
Moistening effect
| Classification | Average mark |
| Operational instances 4 | 3.4 [(4 point * 5)+(3 point * 4)+(2 point * 1)/10] |
| Operational instances 5 | 3.6 [(4 point * 6)+(3 point * 4)/10] |
| Operational instances 6 | 3.9 [(5 point * 1)+(4 point * 7)+(3 point * 2)/10] |
| Comparison example 1 | 2.5 [(3 point * 5)+(2 point * 5)/10] |
(1: excessively poor, 2: poor, 3: common, 4: good, 5: the best)
The result of comprehensive upper table 2, if comparing with conventional cosmetic comparison example 1, can see
The moistening effect going out cosmetics of the present invention is the best.Especially with containing tear wax linteus extract,
The cosmetics of the operational instances 6 that the cosmetic material of ginseng fruit extracts and Semen Vitis viniferae extract is made
Moistening effect is best.
[industrial applications]
The cosmetic material of the present invention and cosmetics be used alone tear wax pore fungi (Ceriporia lacerata,
CL) extract, or use in above-mentioned tear wax linteus extract add ginseng fruit extracts and
The raw material of Semen Vitis viniferae extract, not only possesses whitening, smoothing wrinkle, antioxidation, imparting skin elasticity, skin
The superior efficacy of skin regeneration, additionally it is possible to promoting customer satisfaction, industrial applications is extensive.
Claims (4)
1. the cosmetic material containing tear wax linteus extract, it is characterised in that
Wax pore fungi 2～3 times is torn with drinking water washing,
Then use freezer dryer to be dried, the tear wax pore fungi after lyophilization is put
Enter pulverizer pulverize, the powder gone out by 80～120mesh strainer filterings, be positioned over-15～
Freezing keeping in the environment of-25 DEG C,
Again the tear wax linters powder of freezing keeping is added to 80% methanol (MeOH) solution
In, add according to the weight ratio of 1:20～30, under normal temperature environment, carry out the extraction of 3～5 days,
The extracting solution of extraction filtered through the first round, 3, carried out 2～4 minutes under conditions of 000 × g
The center of circle separates, and the most only extracts supernatant liquid, carries out filtration treatment through 0.1～0.3 μm filter screen,
Obtain natural material.
Contain the cosmetic material of tear wax linteus extract, its feature the most according to claim 1
It is,
Natural material is tear wax linteus extract 1～99wt% and ginseng fruit extracts
1～99wt% is mixed,
Above-mentioned ginseng fruit extracts is, washs ginseng berry (Panax with drinking water
Ginseng) 2～3 times, freezer dryer is then used to be dried process, after lyophilization
Ginseng berry dried object add in ethanol solution, add according to the weight ratio of 1:2～4,
Extract through circulation, be positioned over concentrating under reduced pressure in the environment of 35～45 DEG C after filtration, it is thus achieved that contain
There is the cosmetic material of tear wax linteus extract.
Contain the cosmetic material of tear wax linteus extract, its feature the most according to claim 1
It is,
Natural material is tear wax linteus extract 1～98wt%, ginseng fruit extracts
1～98wt%, the natural material that Semen Vitis viniferae extract 1～30wt% is mixed,
Semen Vitis viniferae extract is, adds 10 times of deals in Semen Vitis viniferae powder 300g
MeOH, uses vibrating sieving machine to carry out 3 extractions repeatedly of each 6 hours, passes through
Filter paper (Watman No.2) filters, and uses Rotary Evaporators concentrating under reduced pressure to process, obtains
Obtain cosmetic material.
4. the cosmetics containing tear wax linteus extract, it is characterised in that by claim 1
To the cosmetic material according to any one of 3,1～30wt% according to cosmetics gross weight add
Add in cosmetics.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150027093A KR101522415B1 (en) | 2015-02-26 | 2015-02-26 | Cosmetic composition including an acanthus extract of ceriporia lacerata and cosmetics using the same |
| KR10-2015-0027093 | 2015-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105919922A true CN105919922A (en) | 2016-09-07 |
Family
ID=53395330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510792535.1A Pending CN105919922A (en) | 2015-02-26 | 2015-11-17 | Cosmetic composition including an acanthus extract of ceriporia lacerata and cosmetics using the same |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR101522415B1 (en) |
| CN (1) | CN105919922A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494302A (en) * | 2020-06-12 | 2020-08-07 | 洋浦吉商生物科技有限公司 | Prebiotics whitening anti-aging fermented cosmetic |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101617730B1 (en) * | 2015-05-29 | 2016-05-03 | 한상선 | Cosmetic composition with the extract of ginseng berry and grape seed and cosmetics using the same |
| KR101774414B1 (en) * | 2015-08-13 | 2017-09-05 | (주)퓨젠바이오 | Composition for improving skin condition comprising exopolysaccharide produced by ceriporia lacerata as an active ingredient |
| KR101655878B1 (en) * | 2015-10-08 | 2016-09-08 | (주)퓨젠바이오농업회사법인 | Composition for preventing hair loss and enhancing hair growth comprising exopolysaccharide produced by ceriporia lacerata as an active ingredient |
| KR101682108B1 (en) * | 2015-10-08 | 2016-12-02 | (주)퓨젠바이오농업회사법인 | Composition for blood flow improvement comprising exopolysaccharide produced by ceriporia lacerata as an active ingredient |
| KR101655882B1 (en) * | 2015-10-08 | 2016-09-08 | (주)퓨젠바이오농업회사법인 | Composition for eliminating hangover comprising exopolysaccharide produced by ceriporia lacerata as an active ingredient |
| KR101712557B1 (en) | 2015-10-29 | 2017-03-06 | 한상선 | Cosmetic composition including a ceriporia lacerata and green tea and cosmetics using the same |
| KR101682101B1 (en) * | 2015-11-26 | 2016-12-02 | (주)퓨젠바이오농업회사법인 | Composition for skin protection against uv comprising exopolysaccharide produced by ceriporia lacerata as an active ingredient |
| KR101784101B1 (en) | 2016-04-05 | 2017-11-06 | 주식회사 씨엘바이오 | The ladies genital area cleanser cosmetic composition for comprising the mixture of Ceriporia lacerata |
| KR101835661B1 (en) | 2016-09-19 | 2018-03-07 | 한상선 | A cosmetic composition containing ceriporia lacerata extract for alleviating skinitching and preventing dermatitis and cosmetics container including the same |
| KR101712559B1 (en) * | 2016-09-19 | 2017-03-06 | 한상선 | A cosmetic composition containing ceriporia lacerata extract for skin-whitening and skin-antiwinkle and cosmetics container including the same |
| KR102150595B1 (en) * | 2017-06-30 | 2020-09-01 | (주)퓨젠바이오 | Pharmaceutical composition for treating scar comprising culture medium of ceriporia lacerata |
| KR20200133063A (en) | 2019-05-15 | 2020-11-26 | 김병천 | A cosmetic composition comprising a culture of Ceriporia lamaritus for skin improvement |
| KR102025611B1 (en) | 2019-05-15 | 2019-11-05 | 김병천 | A composition comprising a culture of Ceriporia lamaritus for preventing or treating of atopic dermatitis |
| KR20210101707A (en) | 2020-02-10 | 2021-08-19 | 농업회사법인 주식회사 미드숨비 | Composition comprising a fermented lactobacillus salivarius for preventing or improving of atopic dermatitis |
| KR102658532B1 (en) * | 2021-06-25 | 2024-04-19 | (주)퓨젠바이오 | Method of Extracting Exosome from Ceriporia Lacerata |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140193454A1 (en) * | 2013-01-09 | 2014-07-10 | Byoung Cheon KIM | Method from preparing ceriporia lacerata culture extract and pharmaceutical composition for prevention or treatment of diabetes and diabetic complications comprising ceriporia lacerata culture extract as active ingredient |
| CN104277986A (en) * | 2014-09-30 | 2015-01-14 | 浙江大学 | Ceriporia lacerata strain and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140128712A (en) * | 2013-04-29 | 2014-11-06 | 고려대학교 산학협력단 | Ceriporia Lacerata KUC8111, method for isolating biomass from the microorganism and method for removing of cadmium using the same |
-
2015
- 2015-02-26 KR KR1020150027093A patent/KR101522415B1/en active IP Right Grant
- 2015-11-17 CN CN201510792535.1A patent/CN105919922A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140193454A1 (en) * | 2013-01-09 | 2014-07-10 | Byoung Cheon KIM | Method from preparing ceriporia lacerata culture extract and pharmaceutical composition for prevention or treatment of diabetes and diabetic complications comprising ceriporia lacerata culture extract as active ingredient |
| CN104277986A (en) * | 2014-09-30 | 2015-01-14 | 浙江大学 | Ceriporia lacerata strain and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494302A (en) * | 2020-06-12 | 2020-08-07 | 洋浦吉商生物科技有限公司 | Prebiotics whitening anti-aging fermented cosmetic |
| CN111494302B (en) * | 2020-06-12 | 2020-11-20 | 洋浦吉商生物科技有限公司 | Prebiotics whitening anti-aging fermented cosmetic |
Also Published As
| Publication number | Publication date |
|---|---|
| KR101522415B1 (en) | 2015-05-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105919922A (en) | Cosmetic composition including an acanthus extract of ceriporia lacerata and cosmetics using the same | |
| JPH11335233A (en) | Melanogenesis inhibitor and cosmetic composition | |
| KR20090055309A (en) | A cosmetic composition for skin whitening and treating wrinkles | |
| KR102326796B1 (en) | Cosmetic materials composition for skin anti-oxidant and skin-soothing, Cosmetic materials using the same and Manufacturing method thereof | |
| KR102193712B1 (en) | Cosmetic materials composition for skin-moisturizing and skin-soothing, Cosmetic materials using the same and Manufacturing method thereof | |
| JPH11279069A (en) | Active oxygen eliminating agent | |
| JPH11228339A (en) | Melanin generation suppresser and preparation for external use for skin | |
| KR102142426B1 (en) | Cosmetic materials composition for skin-whitening and skin-soothing, Cosmetic materials using the same and Manufacturing method thereof | |
| CN111973481A (en) | Blue ketone peptide repair essence and preparation method thereof | |
| JP2000128728A (en) | Cosmetic composition | |
| KR101574556B1 (en) | Cosmetic composition containing extract of Dioscorea bulbifera L., Angelica keiskei, Hibiscus esculentus and Colocasia antiquorum Schott et Endl. var. esculenta Engl. for improving skin moisture | |
| CN112137919B (en) | Application of dictyophora indusiata egg extract in preparation of external beauty and skin care products and external beauty and skin care products based on same | |
| KR20150062624A (en) | Cosmetic Composition Comprising Gracilaria verrucosa (Hudson) Paperfuss Extract, Undaria peterseniana Extract and Sargassum siliquastrum (Mertens) C. Agardh Extract | |
| JP2000159627A (en) | Elastase activity inhibitor and cosmetic composition | |
| KR101019094B1 (en) | Method for preparing cosmetic water for whitening | |
| JP7338842B2 (en) | wrinkle-improving composition and wrinkle-improving skin cosmetic | |
| KR102130243B1 (en) | A cosmetic composition for skin whitening, anti-wrinkle, anti-aging, and anti-oxidation containing glutathione, natural spicule powder, acetyl hexapeptide and broussonetia kazinoki extract | |
| KR20150086922A (en) | Composition for relieving skin irritation and moisturizing skin containing natural fermented pine leaf extract | |
| KR20200134929A (en) | Cosmetic composition containing complex medicinal herbs extract for skin whitening and anti-wrinkle effect and manufacturing method thereof | |
| KR101236348B1 (en) | Pack Composition | |
| CN105796408B (en) | Composition of plant extracts and its application in cosmetics and fluid composition and preparation method thereof of removing ornaments and formal dress | |
| JP2002179547A (en) | Bleaching preparation | |
| KR20160092165A (en) | Method of manufacturing cosmetic containing extracts of nelumbo nucifera | |
| CN107375154A (en) | A kind of nti-freckle white composition and preparation method thereof only | |
| JPH10175814A (en) | Skin preparation for external use and bathing agent containing garcinia extract |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160907 |
|
| WD01 | Invention patent application deemed withdrawn after publication |