KR101617730B1 - Cosmetic composition with the extract of ginseng berry and grape seed and cosmetics using the same - Google Patents

Abstract

The present invention relates to a cosmetic composition mixed with: a ginseng berry extract having skin aging controlling, blood circulation improving, skin tone improving, and antioxidant effects; and a grape seed extract having excellent antioxidant and anti-inflammatory functions. The present invention also relates to cosmetics produced by adding the cosmetic composition at a specific quantity of the total weight of the cosmetics.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition comprising a ginseng fruit, a grape seed extract,

The present invention relates to a cosmetic composition comprising a ginseng fruit extract having skin aging inhibitory effect, blood circulation improvement, skin tone improving effect and antioxidative function, a grape seed extract having excellent antioxidative and antiinflammatory functions, To a cosmetics product prepared by adding a certain amount of cosmetics.

Environmental pollution caused by rapid industrialization and the life of complex metropolitan cities have a great influence on the patterns of consumer life of modern people. One of the changes in life patterns is a well-being trend to increase life satisfaction.

This well-being trend is a phenomenon that promotes naturalism in addition to organic foods. In the cosmetics industry, it also minimizes the use of artificial ingredients and continues to show naturalistic cosmetics and cosmetics for extracting natural ingredients that protect and improve skin through natural ingredients. , Thereby gaining explosive popularity among consumers.

The present invention intends to provide a safe, effective and functional cosmetic composition and a cosmetic product which can provide skin protection and skin improvement effect using natural materials in accordance with such cosmetic trends.

Korean Patent Publication No. 2003-0017300 (published date 2003.03.03) Korean Patent Publication No. 10-2011-0041098 (published date April 21, 2011)

As described above, the present invention provides a cosmetic composition comprising a ginseng fruit extract having skin aging inhibitory effect, blood circulation improvement, skin tone improving effect and antioxidative function, a grape seed extract having excellent antioxidative and antiinflammatory functions, To a cosmetic product by adding a certain amount of the total weight of the cosmetic product.

In order to achieve the above object,

The present invention relates to a composition comprising 1 to 99 wt% of a ginseng fruit extract,

The present invention provides a cosmetic composition comprising a mixture of 1 to 99 wt% of a grape seed extract and a ginseng fruit and a grape seed extract.

And cosmetics including the ginseng fruit and the grape seed extract prepared by adding the cosmetic composition at 1 to 30 wt% based on the total weight of the cosmetic.

The cosmetic composition comprising the ginseng fruit, the grape seed extract, and the cosmetic composition containing the extract according to the present invention is excellent in the function of converting the active oxygen which is a cause of skin aging and adult diseases due to antioxidative function into a substance free of harm.

In other words, it has excellent antioxidant activity that inhibits oxidation by free radicals, thereby preventing aging of the skin, exhibiting melanin inhibitory activity that is highly effective in inhibiting melanin formation in cells, and does not show cytotoxicity.

In addition, it has an excellent skin safety and is suitable as a natural raw material for cosmetics.

Hereinafter, a detailed description will be given of the above technical constitution.

As described above, the cosmetic composition comprising the ginseng fruit and grape seed extract according to the present invention is prepared by mixing 1 ~ 99wt% of ginseng fruit extract and 1 ~ 99wt% of grape seed extract.

Ginseng is a perennial plant belonging to Araliaceae. It has been used for medicinal purposes since 2000 years.

Ginseng contains more than 30 kinds of ginsenosides, which are saponin compounds, and polyacetylenes, phenolic compounds, acidic polysaccharides, peptides, alkaloids and amino acids derivatives as a non saponin system.

Ginseng has a different composition depending on each part (root, fruit, leaf) and has a pharmacological effect accordingly. Ginseng fruit is cultivated in perennial plant ginseng in the 3rd ~ 4th year.

The fruit extract of ginseng improves the flow of blood in the skin and has an effect of improving oxygen partial pressure and skin tone.

Ginseng fruit is different from roots in the composition of ginsenoside, which is known to have a different effect from roots because it has a higher Ginsenoside Re component than roots. Ginsenoside Re inhibits phosphorylation of CDK2 in Thr160 by increasing p21 production when treated with AGS cell line, a gastric cancer cell line, as a single substance after steam heating.

In particular, the fruit of ginseng has skin aging inhibitory effect, blood circulation improvement and skin tone improving effect, antidiabetic effect, anti-cancer effect, anti-allergic effect and alcohol decomposition effect.

The structure of Ginsenoside Re is as follows.

Ginsenoside Re having such a structure has a function of antidiabetic effect, vasodilation effect, cytotoxic effect, antioxidant efficacy, immunity enhancement efficacy, anti-inflammatory efficacy and gastric protective efficacy by protopanaxatrol (PT) .

The ginseng fruit extract maximizes the extraction yield of ginsenoside Re,

Panax ginseng was washed with drinking water 2-3 times and then dried with a freeze dryer for 3-4 days. The freeze-dried ginseng fruit was crushed to a size of 0.4-0.5 mm, and the ginseng fruit powder: distilled water was added to 1 : 30, followed by addition of Viscozyme, a carbohydrase, added at 1 to 2 wt% of the total weight of the ginseng fruit pulverized product, followed by shaking extraction at 55 to 60 ° C for 3 to 4 hours, followed by filter filtration .

The grape (Vitis vinifera Linne) is rich in resveratrol, known as an antioxidant and phenolic compounds such as anthocyanins, benzoic acid, flavonol, procyanidin, and prophylgallate, as well as organic acids, vitamins and minerals, Hardening, stroke, prevention and treatment of heart disease, anti-cancer, antioxidant, antifungal action. And grape seed contains antioxidants such as catechin, resveratrol and tannin, and has physiological effects such as antioxidation, anti-inflammation, and blood cholesterol lowering.

Polyphenol is an antioxidant that converts harmful oxygen, which is active oxygen in our body, into harmless substance. It protects DNA damaged by active oxygen, The antioxidant ability to protect enzymes is great, and it lowers the risk for various diseases.

In the present invention, the grape seed is prepared in the form of an extract, and the extract is obtained by pulverizing grape seed using a grinding apparatus, extracting it with a solvent, concentrating and lyophilizing it to obtain a crude extract, ) At a weight ratio of 1: 1.5 to 2,

After fractionation with petroleum ether, the fractionated petroleum ether layer is concentrated under reduced pressure at 23 ~ 27 ℃ to obtain petroleum ether fraction.

More specifically, 5 kg of Campbell grape seeds are ground with a cutting mill, extracted with 65% acetone solvent, concentrated, and lyophilized to obtain 300 g of crude extract. The crude extract (300 g) was suspended in 700 mL of water, and then extracted with the same amount of petroleum ether three times. Next, the petroleum ether fraction is concentrated under reduced pressure at 25 ° C to obtain 30g of petroleum ether fraction.

In the present invention, the cosmetic composition is added in an amount of 1 to 30 wt% based on the total weight of the cosmetic product to prepare a cosmetic product.

The components of the cosmetics are largely divided into Aqueous and Oil phaes. The aqueous component is soluble in water and the oily component is an oil-soluble component. Typical examples of water-based ingredients include glycerin, which is used as a humectant, and oil-based components, such as oil and wax. These are basically used in most cosmetics. As a result, cosmetics are composed of an aqueous component and an oily component properly mixed, and include purified water, oily ingredients, a surfactant, a moisturizer, a perfume, and a functional ingredient.

The purified water accounts for more than 70% of the cosmetics. In the past, it was merely a base for making cosmetics. However, by using water such as volcanic rocks, tree sap, ice water, and floral water, have.

The oil-based raw material is used for preventing evaporation of water to prevent drying, softening the feel of the skin, and improving the feeling of use. Animal oil; Mineral oil; Synthetic oils such as isopropyl myristate, 2-oxydodecyl myristate, and the like; Waxes such as beeswax, candelilla wax and jojoba oil; Cetyl alcohol, and higher alcohol such as lauryl alcohol.

The surfactants are collectively referred to as materials having structural characteristics that have a hydrophilic group and a hydrophilic group in one molecule in chemical structure. Surfactants are ionic on one side and soluble in water and on the other side they are like hydrocarbons and dissolve in oil.

The moisturizer may be healthy and resilient if it has enough moisture on the skin. By using a moisturizing agent, moisture can be put on our skin or hair to prevent drying. Examples of the moisturizing agent used in cosmetics include polyhydric alcohols such as glycerin, propylene glycol, and polyethylene glycol; Natural moisturizing factors such as sodium lactate, sodiphene PCA, and sodium hyaluronate.

The colorant may be incorporated in cosmetics to express color, have coating power, or reflect ultraviolet light. Some makeup products, such as foundation and eye shadow, are used for color, while some basic cosmetics are used for visual effects. Controversy has arisen as a cause of human harmful factors such as carcinogenicity and contact dermatitis. Representative ingredients include tar pigment, natural pigment, and inorganic pigment.

The polymeric substance refers to a large compound having a large molecular weight and is used in some applications as a thickener, a film forming agent, a moisturizing agent, or a surfactant depending on the application. Typical examples are Quince seed gum, Xanthan gum, and carboxyl vinyl polymer.

The fragrance can be used to increase the value of cosmetics by giving good fragrance to cosmetics and to eliminate the odor peculiar to the raw materials. Nowadays, fragrance therapy called "aromatherapy" is introduced, and by using herbal scent in cosmetics, it is trying to give mental stability and comfort to modern people suffering from stress and various diseases. However, fragrances also vary from person to person and there are many side effects, so proper use ratio should be taken into consideration when mixing in cosmetics.

However, the antidiabetic effect and mechanism by Ceriporia lacerata is not known at present. In this study, we investigated the cytotoxicity (reduction of survival rate, induction of cell death) and mechanism of Dex administration in rat pancreatic beta cell line (INS-1), and at the same time, the extract of Ceriporia lacerata extract, CLE ) To Dex-induced INS-1 cytotoxicity. In addition, we evaluated the effect of Dex on the induction of steroid diabetes and the effect and mechanism of Dex induced diabetes inhibition by CLE in Wistarrat.

Preservatives: When you use cosmetics, cosmetics may be deteriorated by contamination with microorganisms. When cosmetics change, there is a problem with stability, but it can cause skin diseases by microorganisms, which also causes safety problems. In cosmetics, it is preferable to use a mixture of various kinds of preservatives rather than a single preservative in terms of efficacy, so it is preferable to mix them. However, preservatives have a controversial safety that adversely affects the human body. Representative components include parabens, imidazolidinyl urea, phenoxyethanol, and the like.

Hereinafter, the technical composition of the cosmetic composition according to the present invention and the cosmetic composition containing the cosmetic composition will be described in detail with reference to examples.

[ Example  One]

Ginseng fruit, including grape seed extract Cosmetics  Composition

In Example 1, ginseng fruit extract and grape seed extract are blended in the same weight ratio and used as a cosmetic composition.

At this time, the ginseng fruit extract was prepared by washing the ginseng fruit with drinking water 2-3 times, then drying it with a freeze dryer, adding the freeze-dried ginseng fruit extract to ethanol, adding the mixture at a weight ratio of 1: 2, refluxing, Concentration under reduced pressure is obtained.

The grape seed extract was prepared by pulverizing 5kg of Campbell grape seed with a cutting mill, extracting with 65% acetone solvent, concentrating and lyophilizing to obtain 300g crude extract. The crude extract (300 g) was suspended in 700 mL of water, and then extracted with the same amount of petroleum ether three times. The petroleum ether layer, which is then fractionated, is concentrated under reduced pressure at 25 ° C. to obtain 30 g of petroleum ether fraction.

Accordingly, the cosmetic composition according to the present invention comprises the grape seed extract as a mixture of ginseng fruit extract.

[ Example  2]

Example  1 of Cosmetics  Cosmetics manufactured using the composition

20 wt% of the cosmetic composition of Example 1; 2.5 wt% of lipophilic monostearic acid glycerin; 2.0 wt% of stearyl alcohol; 2.2 wt% stearic acid; 1.0wt% wax; Polysorbate 60 1.5 wt%; 0.6 wt% sorbitan stearate; 1.0 wt% of hydrogenated vegetable oil; Squalane 3.0wt%; Mineral oil 5.5wt%; 5.5 wt% of trioctanoin; Dimethicone 1.0wt%; 0.1 wt% of sodium magnesium silicate; 5.5 wt% glycerin; Betaine 3.0 wt%; 1.0 wt% triethanolamine; 4.0 wt% sodium hyaruronate; Preservative, incense, pigment 0.01wt%; A nutrient cream is prepared by mixing 40.59wt% of purified water.

[ Comparative Example  One]

Comparative Example 1 is a nutrition cream not containing the cosmetic composition according to the present invention,

3.5 wt% of lipophilic monostearic acid glycerin; 4.0 wt% of stearyl alcohol; 3.2 wt% stearic acid; Wax 2.0wt%; Polysorbate 60 2.5 wt%; 1.6 wt% sorbitan stearate; 2.0 wt% of hydrogenated vegetable oil; Squalane 4.0wt%; Mineral oil 5.5wt%; 5.5 wt% of trioctanoin; Dimethicone 1.0wt%; 1.1 wt% sodium magnesium silicate; 6.5 wt% glycerin; Betaine 4.0 wt%; 3.0 wt% of triethanolamine; 5.0 wt% sodium hyaruronate; Preservative, incense, pigment 0.01wt%; The nutrient cream is made by mixing 45.59wt% purified water.

[ Test Example  One]

remind Example  2 and Comparative Example  1 Antioxidant Activity of Cosmetics

Each of the cosmetic samples of Example 2 and Comparative Example 1 was diluted with 50% dimethylsulfoxide (DMSO), and 50 μl of each cosmetic sample was taken. 10 mM DPPH (1,1-diphenyl-2 picrylhydrazyl) solution was added and vortexed for 10 seconds. Then, 1 mL of distilled water was added, and the solution was left at 40 DEG C for 40 minutes and absorbance was measured at 517 nm in comparison with the comparative example.

As a result of measuring the antioxidative activity at 40 ° C, Example 2 was measured at 50.52%, and Comparative Example 1 was measured at 12.19%.

[ Test Example  2]

remind Example  2 and Comparative Example 1,

Skin tests were conducted to examine the degree of skin irritation of the cosmetics prepared in Example 2 and Comparative Example 1.

Forty adults were selected for skin test. The age range is 25 to 60 years old, with 10 males and 30 females.

The subjects were divided into two groups of 20 persons. The cosmetic samples of Example 4 were applied to the first group and the cosmetic samples of Comparative Example 1 were applied to the upper arms. After 1 hour, the skin reactions were visually inspected for the first time, After 24 hours, secondary visual inspection was performed again. The results are shown in Table 1 below.

Skin irritation division Degree of skin irritation Example 2 ○ Comparative Example 1 ○

(?: No skin change,?: Mild erythema, x: marked erythema)

As shown in Table 1, it was confirmed that both Example 2 and Comparative Example 1 had no skin change and could be safely used without irritating the skin.

The cosmetic composition comprising the ginseng fruit and the grape seed extract according to the present invention is highly industrially applicable because it has the effect of whitening, wrinkle improvement, antioxidation, skin elasticity and skin regeneration by the active ingredient contained in the ginseng fruit and the grape seed.

Claims (4)

Panax ginseng was washed with drinking water 2-3 times and then dried with a freeze dryer for 3-4 days. The freeze-dried ginseng fruit was crushed to a size of 0.4-0.5 mm, and the ginseng fruit powder: distilled water was added to 1 : 30, and then 50 wt% of ginseng fruit extract extracted with a carbohydrase, Viscozyme,
And 50 wt% of grape seed extract,

Wherein the ginseng fruit extract is obtained by adding Viscozyme to 1 to 2 wt% of the total weight of the ginseng fruit pulverized product, filtering the mixture by shaking at 55 to 60 ° C for 3 to 4 hours, and filtering the ginseng fruit. ≪ / RTI >





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