CN107375154A - A kind of nti-freckle white composition and preparation method thereof only - Google Patents
A kind of nti-freckle white composition and preparation method thereof only Download PDFInfo
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- CN107375154A CN107375154A CN201710844000.3A CN201710844000A CN107375154A CN 107375154 A CN107375154 A CN 107375154A CN 201710844000 A CN201710844000 A CN 201710844000A CN 107375154 A CN107375154 A CN 107375154A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The present invention discloses a kind of nti-freckle white composition only, is made up of the composition of following percentage composition：30~50% Fols Rosae extract, 20~40% bletilla striata extract, 20~40% Herba Lysimachiae foenumgraeci extract.The composition of the present invention is made of galenical, natural harmless；Fols Rosae extract therein has the functions such as delaying skin cell ageing, promoting blood circulation, strengthens the vitality of Skin Cell, absorbability of the lifting Skin Cell to skin care ingredients such as nti-freckle, whitenings；And bletilla striata extract and Herba Lysimachiae foenumgraeci extract have obvious inhibitory action to tyrosinase, the combination of Fols Rosae extract, bletilla striata extract and Herba Lysimachiae foenumgraeci extract three can be obviously improved the effect of spot-removal function of the present composition and net white muscle skin, play a part of Synergistic.
Description
Technical field
The present invention relates to a kind of composition, more particularly to a kind of nti-freckle white composition and preparation method thereof only.
Background technology
Gloomy skin and color spot are melanocytes in the uneven distribution of skin surface and the result of accumulation.Melanin is
It is present in the melanocyte synthesis of basal layer of epidermis, forerunner's tyrosine generates under tyrosinase effect in melanosome
Melanin, increase makes patient that chloasma occur to this melanin extremely in epidermis.Melanin is most important pigment in skin,
It determines our colour of skin.Meanwhile melanin is also the natural defence system of human body skin, ultraviolet can be resisted to skin
Injury.But when melanin produces excessive or skewness, it can but cause pigementation, form blackspot, influence appearance.Junket ammonia
Sour enzyme is the key enzyme of dermal melanin biosynthesis, rate-limiting enzyme, and activity and the B16 cell amount of tyrosinase are in positive relationship.
The effect of commercially available spot-eliminating skin care product, composition was mostly biological agent or chemicals, with consumer's more emphasis
Cosmetic safety, natural, green, health turn into the Main way of cosmetics research and development, and galenical is by as main cosmetics work(
Imitate composition.
The content of the invention
The purpose of the present invention is the shortcomings that being directed to above-mentioned prior art, there is provided a kind of pure natural nti-freckle only white composition and
Its preparation method.Said composition is made up of plant extracts, and natural harmless, freckle effect is good.
To reach its purpose, the technical solution adopted in the present invention is：
A kind of nti-freckle white composition only, is made up of the composition of following percentage composition：30~50% Fols Rosae extract, 20
~40% bletilla striata extract, 20~40% Herba Lysimachiae foenumgraeci extract.
As the preferred scheme of the present invention, the composition is made up of the composition of following percentage composition：40% China rose
Extract, 30% bletilla striata extract, 30% Herba Lysimachiae foenumgraeci extract；
The Fols Rosae extract be China rose alcohol extracting thing, bletilla striata extract be the bletilla striata water extract, lavender
Extract is the alcohol extracting thing of lavandulae flos.
Only white composition can be prepared into various skin care formulations to the nti-freckle of the present invention with reference to skin care field customary adjuvant, such as
Facial mask, essence, face cream, mildy wash, toner etc..
China rose【Latin name：Rosa chinensis Jacq.】It is a kind of common rose family Rosa Chinese herbal medicine,
Also known as Chinese rose perpetual bloom, in China, most area has plantation.The traditional Chinese medical science thinks that its is sweet in flavor and warm in property, there is promoting blood circulation for regulating menstruation, detumescence
The effect of removing toxic substances, cure mainly irregular menstruation, dysmenorrhoea, ulcerative carbuncle pyogenic infections, scrofula etc..A variety of diseases of human body and presenility excessively are all
Because oxygen radical (free radical) excessive in vivo causes normal cell Oxidative demage, it is to prolong to eliminate free radical excessive in vivo
The important channel of slow skin senescence.The extract of China rose has the ability for removing DPPH free radicals, and its antioxidation is with carrying
Thing concentration is taken to increase and gradually strengthen, the aldehydes matter such as contained Quercetin, tannin, gallic acid can capture peroxylradicals,
Block peroxidating chain reaction progress and oil-control aoxidize.
The bletilla striata【Latin name：Bletilla striata(Thunb.)Reichb.f.】This bulbous plant is drafted a document, is orchid family
Bletilla striata category.The bletilla striata is used as traditional Chinese medicine always, and its major function is sore hemostasis, tonifying lung and detumescence and promoting granulation, can be treated
Haematemesis, tuberculosis etc..Biological Functional Assays show that bletilla striata extract has bright to the human dermal fibroblast cell of in vitro culture
Aobvious promotion growth, while there are anti-aging effects to human fibroblasts, can be with delaying cell aging.Bletilla striata extract
Containing substantial amounts of glucomannans class material, it is heavy that bletilla striata glucomannans does not produce with acid, alkali and some common electrolyte
Form sediment, there is preferable salt tolerance in skin care item.Because bletilla striata glucomannans can be penetrated into skin histology, excite interior
Source property quasi-SOD activity, simultaneously as its own contained bletilla striata SOD and the effect of possessed quasi-SOD, and extremely strong antibacterial disappear
Inflammation effect, can remove superoxide radical to greatest extent, suppress the oxidizing process of unrighted acid, so as to reduce pigmentation
Generation, make skin present nature it is pale.
Lavender【Latin name：lavandula pedunculata】There is the good reputation of " fragrant medicinal herbs ", be adapted to any skin
Skin.Contain bergamio, acetic acid lavender ester linalool, geraniol, Ingredients Such As Coumarin, tool in the extract of lavandulae flos
There is the effect of good antibacterial and desalination scar.Can freckle removing and whitening, the tender skin of anti-wrinkle, impaired skin regeneration can be promoted and recovered,
Clothing grass extract has stronger inhibitory action to tyrosinase.
The present invention is made with the net contour painting effect of nti-freckle using Fols Rosae extract, bletilla striata extract and Herba Lysimachiae foenumgraeci extract
Composition；Wherein, Fols Rosae extract has the functions such as delaying skin cell ageing, promoting blood circulation, strengthens the vitality of Skin Cell,
Lift absorbability of the Skin Cell to skin care ingredients such as nti-freckle, whitenings；And bletilla striata extract and Herba Lysimachiae foenumgraeci extract are to junket ammonia
Sour enzyme has obvious inhibitory action, and the combination of Fols Rosae extract, bletilla striata extract and Herba Lysimachiae foenumgraeci extract three can be notable
The effect of lifting the spot-removal function of the present composition and net white muscle skin, plays a part of Synergistic.
The preparation method of the nti-freckle white composition only, comprises the following steps：
1. the preparation of Fols Rosae extract：It is constant that China rose is dried to moisture, crushed, sieving, then at 60~80 DEG C
Lower 1~2h of alcohol steep that concentration is 70%~90%, extract solution filtering, is concentrated into medicinal extract, obtains Fols Rosae extract；
2. the preparation of bletilla striata extract：Bletilla striata medicinal material coarse powder is eluted with water, puts into boiling water after boiling 20~40min, stops
Only heat, maintain water temperature at 60 DEG C~70 DEG C, then with 0.5~1.5h of ultrasonic wave extraction, extract solution is centrifuged into obtain supernatant, will
Supernatant concentration obtains bletilla striata extract into paste；
3. the preparation of Herba Lysimachiae foenumgraeci extract：Lavandulae flos that will be dry crushes, with the alcohol steep that concentration is 60%~80%,
Take supernatant liquid filtering and be condensed into medicinal extract, obtain Herba Lysimachiae foenumgraeci extract；
4. Fols Rosae extract obtained above, bletilla striata extract and Herba Lysimachiae foenumgraeci extract are mixed to prepare combination by proportioning
Thing.
Extraction of the temperature on China rose functional component influences more apparent, it is contemplated that between the activity and temperature of polyphenoils
Relation, activity is stronger under lower temperature, while avoids ethanol during high temperature from losing too fast possibility, and inventor passes through creative real
Test, the optimum extraction temperature for drawing Fols Rosae extract is 60 DEG C~70 DEG C.The concentration of ethanol carries to China rose antioxidant content
Taking technique has considerable influence, and with the raising of concentration of alcohol, the antioxidant content proportion in Fols Rosae extract gradually increases
Greatly, the recycling of comprehensive ethanol considers, inventor draws the concentration of the ethanol for China rose extraction by creative experiments
It is advisable for 70%~90%.
As the preferred scheme of the present invention, the step 1. in, the drying temperature of China rose is 50 DEG C.
As the present invention preferred scheme, the step 1. in, the preparation method of Fols Rosae extract is：China rose is dried
Do it is constant to moisture, crush, cross 40 mesh sieves, then at 70 DEG C with concentration be 80% alcohol steep 1.5h, extract solution filtering,
Filtrate is concentrated under reduced pressure into medicinal extract with Rotary Evaporators, obtains Fols Rosae extract.
As the present invention preferred scheme, the step 2. in, the preparation method of bletilla striata extract is：Bletilla striata medicinal material is thick
Powder is eluted with water, and puts into boiling water after boiling 30min, stops heating, maintains water temperature at 60 DEG C~70 DEG C, then use ultrasonic wave extraction
1h, extract solution is centrifuged into 4~6min in 6000r/min, supernatant is obtained, by supernatant concentration into paste, obtains bletilla striata extract.
The present invention extracts the polysaccharide in the bletilla striata using ultrasonic wave water extraction, wherein, fragmentation of the ultrasonic wave to bletilla striata cell tissue
The leaching rate of polysaccharide can be improved.
As the present invention preferred scheme, the step 3. in, the preparation method of Herba Lysimachiae foenumgraeci extract is：Dry is smoked into clothing
The showy flowers of herbaceous plants crushes, and is extracted one week at 25 DEG C with the ethanol that concentration is 70%, takes supernatant sieving suction filtration to be concentrated after ethanol is recovered under reduced pressure
Into medicinal extract, Herba Lysimachiae foenumgraeci extract is obtained.
Only white composition can be used for preparing skin care item nti-freckle of the present invention.
Compared with prior art, beneficial effects of the present invention are：The composition of the present invention is made of galenical, naturally
It is harmless；Fols Rosae extract therein has the functions such as delaying skin cell ageing, promoting blood circulation, strengthens the vitality of Skin Cell,
Lift absorbability of the Skin Cell to skin care ingredients such as nti-freckle, whitenings；And bletilla striata extract and Herba Lysimachiae foenumgraeci extract are to junket ammonia
Sour enzyme has obvious inhibitory action, and the combination of Fols Rosae extract, bletilla striata extract and Herba Lysimachiae foenumgraeci extract three can be notable
The effect of lifting the spot-removal function of the present composition and net white muscle skin, plays a part of Synergistic.Using the system of the present invention
Preparation Method can improve the extraction rate of active ingredient in each component raw material, ensure nti-freckle only white composition the effect of.
Embodiment
More clearly to state technical scheme, further illustrate, but can not use with reference to specific embodiment
In the limitation present invention, this is only the section Example of the present invention.
Embodiment 1
Embodiments of the invention provide a kind of nti-freckle white composition only, are made up of the composition of following percentage composition：40%
Fols Rosae extract, 30% bletilla striata extract, 30% Herba Lysimachiae foenumgraeci extract；The Fols Rosae extract is the second of China rose
Alcohol extracting thing, bletilla striata extract are the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Embodiment 2
Embodiments of the invention provide a kind of nti-freckle white composition only, are made up of the composition of following percentage composition：30%
Fols Rosae extract, 40% bletilla striata extract, 30% Herba Lysimachiae foenumgraeci extract；The Fols Rosae extract is the second of China rose
Alcohol extracting thing, bletilla striata extract are the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Embodiment 3
Embodiments of the invention provide a kind of nti-freckle white composition only, are made up of the composition of following percentage composition：50%
Fols Rosae extract, 20% bletilla striata extract, 30% Herba Lysimachiae foenumgraeci extract；The Fols Rosae extract is the second of China rose
Alcohol extracting thing, bletilla striata extract are the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Embodiment 4
Embodiments of the invention provide a kind of nti-freckle white composition only, are made up of the composition of following percentage composition：50%
Fols Rosae extract, 30% bletilla striata extract, 20% Herba Lysimachiae foenumgraeci extract；The Fols Rosae extract is the second of China rose
Alcohol extracting thing, bletilla striata extract are the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Embodiment 5
Embodiments of the invention provide a kind of nti-freckle white composition only, are made up of the composition of following percentage composition：40%
Fols Rosae extract, 20% bletilla striata extract, 40% Herba Lysimachiae foenumgraeci extract；The Fols Rosae extract is the second of China rose
Alcohol extracting thing, bletilla striata extract are the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Embodiment 6
The preparation method of the composition of embodiment 1~5, comprises the following steps：
1. the preparation of Fols Rosae extract：It is constant that China rose is dried to moisture at 50 DEG C, is crushed with pulverizer, crosses 40
Mesh sieve, then extract solution filtering, filtrate is depressurized with Rotary Evaporators with the alcohol steep 1.5h that concentration is 80% at 70 DEG C
Medicinal extract is concentrated into, obtains Fols Rosae extract；
2. the preparation of bletilla striata extract：Bletilla striata medicinal material coarse powder is eluted with water, put into boiling water after boiling 30min, stops adding
Heat, 60 DEG C~70 DEG C are maintained water temperature at, then with ultrasonic wave extraction 1h, extract solution is centrifuged into 5min in 6000r/min, obtains supernatant
Liquid, by supernatant concentration into paste, obtain bletilla striata extract；
3. the preparation of Herba Lysimachiae foenumgraeci extract：Dry lavandulae flos is crushed, with the ethanol that concentration is 70% in 25 DEG C of extractions
One week, take supernatant sieving suction filtration to be condensed into medicinal extract after ethanol is recovered under reduced pressure, obtain Herba Lysimachiae foenumgraeci extract；
4. Fols Rosae extract obtained above, bletilla striata extract and Herba Lysimachiae foenumgraeci extract are mixed to prepare combination by proportioning
Thing.
Comparative example 1
A kind of composition, it is made up of the composition of following percentage composition：50% Fols Rosae extract, the extraction of 50% bletilla striata
Thing；The Fols Rosae extract is the ethanol extract of China rose, and bletilla striata extract is the water extract of the bletilla striata.Preparation method is joined
According to embodiment 6.
Comparative example 2
A kind of composition, it is made up of the composition of following percentage composition：50% Fols Rosae extract, 50% lavender carry
Take thing；The Fols Rosae extract is the ethanol extract of China rose, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.
Preparation method is with reference to embodiment 6.
Comparative example 3
A kind of composition, it is made up of the composition of following percentage composition：50% bletilla striata extract, the extraction of 50% lavender
Thing；The bletilla striata extract is the water extract of the bletilla striata, and Herba Lysimachiae foenumgraeci extract is the ethanol extract of lavandulae flos.Preparation method
With reference to embodiment 6.
Comparative example 4
A kind of Fols Rosae extract, its preparation method are identical with the preparation method of the Fols Rosae extract of embodiment 6.
Comparative example 5
A kind of bletilla striata extract, its preparation method are identical with the preparation method of the bletilla striata extract of embodiment 6.
Comparative example 6
A kind of Herba Lysimachiae foenumgraeci extract, its preparation method are identical with the preparation method of the Herba Lysimachiae foenumgraeci extract of embodiment 6.
Test example
Work is used as using the extract of the composition of embodiment 1~5, the composition of comparative example 1~3, comparative example 4~5 respectively
Property composition prepares face cream.
The preparation method of face cream：Oil phase raw material and Aqueous Phase Raw Material are weighed respectively by the prescription for skin cream of table 1 below, respectively
Oil phase raw material and Aqueous Phase Raw Material are heated to 90 DEG C, Aqueous Phase Raw Material is added in oil phase raw material, homogeneous 5min, rotating speed 6000r/
Min, treat that temperature drops to less than 70 DEG C addition thickeners, stir to less than 60 DEG C addition alkali lye, adjust pH value, continue to be cooled to 45
Active component, preservative are added below DEG C, is stirred.
The prescription for skin cream of table 1
Physicochemical property detects
1. character
It is suitable that obtained face cream is presented viscosity, it is fine and smooth uniformly, stretchability is good.
2.pH values check
A small amount of emulsion is dipped with the pH test paper of moistening respectively to obtained face cream, measures pH value as 6~7.
3. excitant sensitivity test
33 volunteers are invited to be tested：33 volunteers are equally divided into 11 groups, try out obtained face cream respectively, apply
Smear skin and cheek after ear.Once in the morning and once at night, repeat 10 days.Subjects skin does not occur allergy, plays fash and other does not relax
The symptom of clothes.
Clinical effectiveness is tested
Patient data：120 patients, wherein male patient 50, female patient 70,25~50 years old age, average year
32.4 years old age, patient show as face and large area chloasma occur.Patient is randomly divided into 12 groups, every group of 10 people.Wherein, 11
For group respectively using the face cream of embodiment 1~5 and comparative example 1~6, remaining 1 group uses commercially available spot removal and skin care frost.
Treatment method：Avoid eye and face cream is applied to face, the use of 28 days is a course for the treatment of once in the morning and once at night, unite
Count the therapeutic effect of two courses for the treatment of.Meanwhile patient all should notice that guarding against anger guards against sorrow during treatment and after treatment, keep pleasant feelings
Thread, avoid on diet it is excessively pungent stimulate error, pay special attention to avoid abusing cosmetics, disable other spot-eliminating skin care products.
Criterion of therapeutical effect：It is basic to cure：Color spot area regression ＞ 90%, color disappears substantially, and skin is clean white bright；
It is effective：Color spot area regression ＞ 70%, color substantially shoals, and skin is pale than before；
Take a turn for the better：Color spot area regression ＞ 30%, color is thin out, and the colour of skin is without significant change；
It is invalid：Color spot area regression≤30, color change unobvious.
Treatment results refer to table 2
Table 2
It was found from the treatment results of table 2, composition of the invention has the net white effect of good nti-freckle, and positive effect
Better than commercially available spot-eliminating skin care product.The net white effect of nti-freckle of the wherein composition of embodiment 1 is optimal.Fols Rosae extract, the bletilla striata
The combination of extract and Herba Lysimachiae foenumgraeci extract three can play the net white synergistic function of nti-freckle, and can from comparative example 1~6
Know, Fols Rosae extract, bletilla striata extract and Herba Lysimachiae foenumgraeci extract are individually or combination of two is in use, freckle effect is obvious
Decline.
Finally it should be noted that：The above embodiments are merely illustrative of the technical scheme of the present invention and are not intended to be limiting thereof, to the greatest extent
The present invention is described in detail with reference to above-described embodiment for pipe, those of ordinary skills in the art should understand that：Still
The embodiment of the present invention can be modified or equivalent substitution, and without departing from any of spirit and scope of the invention
Modification or equivalent substitution, it all should cover among scope of the presently claimed invention.
Claims (8)
1. a kind of nti-freckle white composition only, it is characterised in that be made up of the composition of following percentage composition：30~50% China rose
Extract, 20~40% bletilla striata extract, 20~40% Herba Lysimachiae foenumgraeci extract.
2. composition as claimed in claim 1, it is characterised in that be made up of the composition of following percentage composition：40% Chinese rose
Flower extract, 30% bletilla striata extract, 30% Herba Lysimachiae foenumgraeci extract；
The Fols Rosae extract is the alcohol extracting thing of China rose, and bletilla striata extract is the water extract of the bletilla striata, and lavender is extracted
Thing is the alcohol extracting thing of lavandulae flos.
3. the preparation method of composition as claimed in claim 1 or 2, it is characterised in that comprise the following steps：
1. the preparation of Fols Rosae extract：It is constant that China rose is dried to moisture, crushed, sieving, is then used at 60~80 DEG C
Concentration is 70%~90% 1~2h of alcohol steep, extract solution filtering, is concentrated into medicinal extract, obtains Fols Rosae extract；
2. the preparation of bletilla striata extract：Bletilla striata medicinal material coarse powder is eluted with water, put into boiling water after boiling 20~40min, stops adding
Heat, 60 DEG C~70 DEG C are maintained water temperature at, then with 0.5~1.5h of ultrasonic wave extraction, extract solution is centrifuged into obtain supernatant, by supernatant
Liquid is condensed into paste, obtains bletilla striata extract；
3. the preparation of Herba Lysimachiae foenumgraeci extract：Dry lavandulae flos is crushed, with the alcohol steep that concentration is 60%~80%, taken
Clear liquid filters and is condensed into medicinal extract, obtains Herba Lysimachiae foenumgraeci extract；
4. Fols Rosae extract obtained above, bletilla striata extract and Herba Lysimachiae foenumgraeci extract are mixed to prepare composition by proportioning.
4. preparation method as claimed in claim 3, it is characterised in that the step 1. in, the drying temperature of China rose is 50
℃。
5. the preparation method as described in claim 3 or 4, it is characterised in that the step 1. in, the preparation of Fols Rosae extract
Method is：It is constant that China rose is dried to moisture, crushed, crosses 40 mesh sieves, is then soaked at 70 DEG C with the ethanol that concentration is 80%
1.5h is carried, extract solution filtering, filtrate is concentrated under reduced pressure into medicinal extract with Rotary Evaporators, obtains Fols Rosae extract.
6. preparation method as claimed in claim 3, it is characterised in that the step 2. in, the preparation method of bletilla striata extract
For：Bletilla striata medicinal material coarse powder is eluted with water, put into boiling water after boiling 30min, stops heating, maintains water temperature at 60 DEG C~70 DEG C,
Then ultrasonic wave extraction 1h is used, extract solution is centrifuged into 4~6min in 6000r/min, supernatant is obtained, by supernatant concentration into thick paste
Shape, obtain bletilla striata extract.
7. preparation method as claimed in claim 3, it is characterised in that the step 3. in, the preparation side of Herba Lysimachiae foenumgraeci extract
Method is：Dry lavandulae flos is crushed, extracted one week at 25 DEG C with the ethanol that concentration is 70%, takes supernatant sieving to filter decompression
Medicinal extract is condensed into after recovery ethanol, obtains Herba Lysimachiae foenumgraeci extract.
8. a kind of purposes of composition as claimed in claim 1 or 2, it is characterised in that the composition is used to prepare skin care
Product.
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| CN107951822A (en) * | 2017-12-05 | 2018-04-24 | 广州赛莱拉干细胞科技股份有限公司 | One kind contains Chinese wolfberry fruit dry cell extract white skin care item only |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107951822A (en) * | 2017-12-05 | 2018-04-24 | 广州赛莱拉干细胞科技股份有限公司 | One kind contains Chinese wolfberry fruit dry cell extract white skin care item only |
| CN117137845A (en) * | 2023-10-12 | 2023-12-01 | 广州西子化妆品科技有限公司 | Whitening and freckle-removing composition and preparation method and application thereof |
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