CN105878713A - Traditional Chinese medicinal composition with efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and preparation method of traditional Chinese medicinal composition - Google Patents
Traditional Chinese medicinal composition with efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and preparation method of traditional Chinese medicinal composition Download PDFInfo
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- CN105878713A CN105878713A CN201410804360.7A CN201410804360A CN105878713A CN 105878713 A CN105878713 A CN 105878713A CN 201410804360 A CN201410804360 A CN 201410804360A CN 105878713 A CN105878713 A CN 105878713A
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Abstract
The invention discloses a traditional Chinese medicinal composition with the efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and a preparation method of the traditional Chinese medicinal composition, belonging to the field of modernization of the Chinese traditional medicine. The traditional Chinese medicinal composition is prepared from the following medicinal materials in parts by weight: 108 parts of rhizoma anemarrhenae, 108 parts of radix scrophulariae, 216 parts of pericarpium papaveris, 108 parts of radix ophiopogonis, 324 parts of flos farfarae, 108 parts of radix asteris, 108 parts of semen armeniacae amarae, 108 parts of lily bulb, and 24 parts of thunberg fritillary bulb. According to the research result on the physicochemical properties and pharmacological effects of the ingredients in the medicinal materials, the preparation method of the traditional Chinese medicinal composition containing the reasonable and stable medicinal materials is obtained. With the adoption of the technical scheme, the prepared medicine is stable and controllable in quality, the curative effects of the prepared medicine are obviously improved compared with those of the existing compositions sold in the market, the taking dosage of the patient is reduced, and therefore, the traditional Chinese medicinal composition has obvious economic and social benefits.
Description
Technical field
The present invention relates to Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma and preparation method thereof, in belonging to
Medicine modernization field.
Background technology
Cough due to consumptive disease is because insufficiency of lung-QI causes, patient often have asthma, cough, cough up phlegm, the symptom of spontaneous perspiration.
Blood pressure is on the low side, and people is the weakest, easily infects exopathogen, also may result in insufficiency of kidney-YANG, makes water liquid run
Unfavorable, the symptom of frequent micturition, dribbling occurs.Bulbus Lilii has nourishing the lung to arrest cough, the effect of the heart is coagulated in heat clearing away, right
The therapeutic effect of cough due to consumptive disease is preferable.
Asthenia and the patient that coughs, dialectical at lung, because of lung governing qi, institute's row of gas, logical flourish internal organs, therefore cough
Cough and all enter lung also.But it is also contemplated that the Coryza Treated by Syndrome Differentiation of taste, just occur coughing though presentation is exopathogen impairing the lung,
Can basic reason be that internal organs are weak.The common loose stool of having loose bowels of patient, the symptom repeatedly delayed.According to " holy Ji is total
Record " described in, " the opinion person that says cough due to consumptive disease, injures one's stomach with lung weak, and battalion defends on the decline, gas is the warmest fill thus also,
Lung governing qi, for the lid of the five internal organs, its circulus venosus follows appetite, lungs impairment caused by overstrain, then make us cough with dyspnea, or saliva pus
Blood, cold and heat tide work, flushed complexion xerostomia, partially sleeping happiness antiperspirant, it is impossible to diet, it is also that skin is become thin.”
The opinion person that says cough due to consumptive disease, injures one's stomach with lung weak, and battalion defends on the decline, gas is the warmest fill thus also, lung governing qi, for
The lid of the five internal organs, its circulus venosus follows appetite, lungs impairment caused by overstrain, then make us cough with dyspnea, or spitting bloody pus, cold and heat tide
Make, flushed complexion xerostomia, partially sleeping happiness antiperspirant, it is impossible to diet, it is also that skin is become thin.
Ermuansou sheet removing heat from the lung and dissipating phlegm, relieving cough, relieving asthma.For asthenia chronic cough, report spring and autumn, phlegm dyspnea of coughing,
Osteopyrexia and fever, hoarseness is low voice speaking, dry mouth dry tongue, accumulation and obstruction of sputum..
The prescription of Ermuansou sheet and preparation method be: Rhizoma Anemarrhenae 108g, Radix Scrophulariae 108g, Pericarpium Papaveris 216g,
Radix Ophiopogonis 108g, Flos Farfarae 324g, Radix Asteris 108g, Semen Armeniacae Amarum 108g, Bulbus Lilii 108g, Bulbus Fritillariae Thunbergii 54g.
Above nine tastes, Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, wheat
Winter boiling secondary, 3 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is dense
Shorten cream into；Flos Farfarae, Radix Asteris 60% alcohol heating reflux extraction three times, 6 hours for the first time, second
Secondary 4 hours, 2 hours for the third time；Semen Armeniacae Amarum deoils, and extracts secondary with 85% alcohol heating reflux, the
One time 3 hours, 2 hours for the second time, united extraction liquid, reclaims ethanol, is condensed into cream.By above-mentioned two
Plant condensed cream to merge, add fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, make granule, be dried, suppress
Become 1100, to obtain final product.
Summary of the invention
First technical problem that the invention solves the problems that is to provide the Chinese medicine of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma
Compositions.
Another technical problem that the invention solves the problems that is to provide the preparation method of above-mentioned Chinese medicine composition.
For achieving the above object, the present invention is by the following technical solutions；
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma, its active component is former by following parts by weight
Material is made: the Rhizoma Anemarrhenae 108 parts, Radix Scrophulariae 108 parts, Pericarpium Papaveris 216 parts, Radix Ophiopogonis 108 parts, Flos Farfarae
324 parts, Radix Asteris 108 parts, Semen Armeniacae Amarum 108 parts, Bulbus Lilii 108 parts, Bulbus Fritillariae Thunbergii 24 parts.
Described active component uses following method to prepare:
1, each raw material is weighed by proportioning raw materials；Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；Know
Mother, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis secondary, collecting decoction, filter, filtrate is condensed into cream；
Flos Farfarae, Radix Asteris alcohol heating reflux extract three times；Semen Armeniacae Amarum deoils, and extracts with alcohol heating reflux
Secondary, united extraction liquid, reclaims ethanol, is condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds hundred
Fine powder and the right amount of auxiliary materials such as conjunction, mixing, make granule, be dried, obtain dried object A.
2, each raw material is weighed by proportioning raw materials；Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；Know
Mother, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis secondary, 3 hours for the first time, 1 hour for the second time, close
And decocting liquid, filtering, filtrate is condensed into cream；Flos Farfarae, Radix Asteris are extracted three times with 60% alcohol heating reflux,
6 hours for the first time, 4 hours for the second time, 2 hours for the third time；Semen Armeniacae Amarum deoils, and adds with 85% ethanol
Circumfluence distillation secondary, 3 hours for the first time, 2 hours for the second time, united extraction liquid, reclaim ethanol,
It is condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, system
Become granule, be dried, obtain dried object A.
Described pharmaceutical composition is possibly together with the acceptable adjuvant of pharmaceutics.
The acceptable adjuvant of described pharmaceutics is selected from starch, microcrystalline Cellulose, sucrose, aspartame, paste
Essence, lactose, Icing Sugar, glucose, sodium chloride, Carboxymethyl cellulose sodium, crospolyvinylpyrrolidone,
Any one in magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and sodium sulfite
Plant or several.
The dosage form of described Chinese medicine composition is peroral dosage form, include but not limited to pill, tablet, capsule or
Oral liquid.The selection of dosage form and the consumption of adjuvant belong to prior art.
A kind of preparation method of the Chinese medicine composition of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma:
Weigh the Rhizoma Anemarrhenae 108 parts, Radix Scrophulariae 108 parts, Pericarpium Papaveris 216 parts, Radix Ophiopogonis 108 parts, Flos Farfarae
324 parts, Radix Asteris 108 parts, Semen Armeniacae Amarum 108 parts, Bulbus Lilii 108 parts, Bulbus Fritillariae Thunbergii 24 parts.Bulbus Lilii,
Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis secondary,
Collecting decoction, filters, and filtrate is condensed into cream；Flos Farfarae, Radix Asteris alcohol heating reflux extract three times；
Semen Armeniacae Amarum deoils, and extracts secondary, united extraction liquid with alcohol heating reflux, reclaims ethanol, be condensed into cream.
Above-mentioned two kinds of condensed creams are merged, adds fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, make granule, dry
Dry, obtain dried object A.
Preferably preparation method is: weigh each raw material by proportioning raw materials；Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into
Fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis secondary, 3 hours for the first time, the
Secondary 1 hour, collecting decoction, filter, filtrate is condensed into cream；Flos Farfarae, Radix Asteris add with 60% ethanol
Circumfluence distillation three times, 6 hours for the first time, 4 hours for the second time, 2 hours for the third time；Semen Armeniacae Amarum goes
Oil, extracts secondary with 85% alcohol heating reflux, and 3 hours for the first time, 2 hours for the second time, merging carried
Take liquid, reclaim ethanol, be condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds fine powders such as Bulbus Lilii and auxiliary
Material is appropriate, mixing, makes granule, is dried, obtains dried object A.
The preparation of the Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma, said preparation becomes with above-mentioned pharmaceutically active
Divide and add the acceptable adjuvant of pharmaceutics, make the acceptable dosage form of pharmaceutics.The present invention is utilized to obtain
When the active component of Chinese medicine composition prepares the various dosage form of required medicine, can be according to art of pharmacy
Prepared by conventional production process.As this active component is mixed with one or more carriers, then make corresponding
Dosage form.
The invention have the advantage that the present invention uses theory of Chinese medical science to analyze prescription composition, contained by each flavour of a drug
The physicochemical property of composition and pharmacological action, research has obtained the preparation method of reasonable, stable active component.
Use technical scheme, on duty go out stable and controllable for quality, curative effect compared with the existing commercial dosage forms
Significantly improve, patient's taking dose reduce pharmaceutical preparation, there is significant economic and social benefit.
Describe technical solution of the present invention by the following examples in detail, do not limit the enforcement of the present invention with this
Scope.
Detailed description of the invention
Embodiment 1: prepare Chinese medicine extract
One, prescription: Rhizoma Anemarrhenae 108g, Radix Scrophulariae 108g, Pericarpium Papaveris 216g, 108g Radix Ophiopogonis, Flos Farfarae
324g, Radix Asteris 108g, Semen Armeniacae Amarum 108g, Bulbus Lilii 108g, Bulbus Fritillariae Thunbergii 24g.
Two, preparation method:
Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, Radix Ophiopogonis add water
Decocting secondary, 3 hours for the first time, 1 hour for the second time, collecting decoction, filtration, filtrate was condensed into cream；
Flos Farfarae, Radix Asteris 60% alcohol heating reflux extraction three times, 6 hours for the first time, 4 hours for the second time,
2 hours for the third time；Semen Armeniacae Amarum deoils, with 85% alcohol heating reflux extract secondary, 3 hours for the first time,
2 hours for the second time, united extraction liquid, reclaims ethanol, is condensed into cream.Above-mentioned two kinds of condensed creams are merged,
Add fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, make granule, be dried, obtain dried object A and amount to 600g.
Embodiment 2: prepare Chinese medicine extract
One, prescription: Rhizoma Anemarrhenae 108kg, Radix Scrophulariae 108kg, Pericarpium Papaveris 216kg, 108kg Radix Ophiopogonis, money
Flos Farfarae 324kg, Radix Asteris 108kg, Semen Armeniacae Amarum 108kg, Bulbus Lilii 108kg, Bulbus Fritillariae Thunbergii 24kg.
Two, preparation method:
Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, Radix Ophiopogonis add water
Decocting secondary, 3 hours for the first time, 1 hour for the second time, collecting decoction, filtration, filtrate was condensed into cream；
Flos Farfarae, Radix Asteris 60% alcohol heating reflux extraction three times, 6 hours for the first time, 4 hours for the second time,
2 hours for the third time；Semen Armeniacae Amarum deoils, with 85% alcohol heating reflux extract secondary, 3 hours for the first time,
2 hours for the second time, united extraction liquid, reclaims ethanol, is condensed into cream.Above-mentioned two kinds of condensed creams are merged,
Add fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, make granule, be dried, obtain dried object A dried object
A amounts to 600kg.
Embodiment 3: prepare tablet
The active component 100g that embodiment 1 obtains, adds microcrystalline Cellulose 40g, cross-linked pvp 7g, tabletting,
Obtain tablet, every tablet weight 0.6g.
Embodiment 4: prepare capsule
The active component 1000g that embodiment 1 obtains, adds starch 250g, encapsulating capsule, obtains capsule, often
Grain weight 0.50g.
Claims (8)
1. the Chinese medicine composition of a removing heat from the lung and dissipating phlegm relieving cough, relieving asthma, it is characterised in that: its activity
Composition is made up of the raw material of following parts by weight: the Rhizoma Anemarrhenae 108 parts, Radix Scrophulariae 108 parts, Semen Papaveris
216 parts of shell, Radix Ophiopogonis 108 parts, Flos Farfarae 324 parts, Radix Asteris 108 parts, Semen Armeniacae Amarum 108
Part, Bulbus Lilii 108 parts, Bulbus Fritillariae Thunbergii 24 parts.
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma the most according to claim 1,
It is characterized in that old point of described activity uses following method to prepare: weigh respectively by proportioning raw materials
Raw material, Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae,
Boiling Radix Ophiopogonis secondary, collecting decoction, filter, filtrate is condensed into cream；Flos Farfarae, Radix Asteris
Extract three times with alcohol heating reflux；Semen Armeniacae Amarum deoils, and extracts secondary with alcohol heating reflux,
United extraction liquid, reclaims ethanol, is condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds hundred
Fine powder and the right amount of auxiliary materials such as conjunction, mixing, make granule, be dried, obtain dried object A.
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma the most according to claim 2,
It is characterized in that: Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris,
Radix Scrophulariae, boiling Radix Ophiopogonis secondary, 3 hours for the first time, 1 hour for the second time, collecting decoction,
Filtering, filtrate is condensed into cream；Flos Farfarae, Radix Asteris are extracted three times with 60% alcohol heating reflux,
6 hours for the first time, 4 hours for the second time, 2 hours for the third time；Semen Armeniacae Amarum deoils, with 85%
Alcohol heating reflux extraction secondary, 3 hours for the first time, 2 hours for the second time, united extraction liquid,
Reclaim ethanol, be condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds fine powders such as Bulbus Lilii and auxiliary
Material is appropriate, mixing, makes granule, is dried, obtains dried object A.
4. fixed according to a kind of removing heat from the lung and dissipating phlegm antitussive in any of the one of claims 1 to 3
The Chinese medicine composition breathed heavily, it is characterised in that: affiliated medicine is possibly together with the acceptable adjuvant of pharmaceutics
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma the most according to claim 4,
It is characterized in that: the acceptable adjuvant of described pharmaceutics selected from starch, microcrystalline Cellulose, sucrose,
Aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, Carboxymethyl cellulose sodium,
Crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine,
Any one or a few in citric acid and sodium sulfite.
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma the most according to claim 4,
It is characterized in that: the dosage form of described Chinese medicine composition is peroral dosage form, including pill, tablet,
Capsule or oral liquid.
7. a preparation method for the Chinese medicine composition of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma, weighs the Rhizoma Anemarrhenae
108 parts, Radix Scrophulariae 108 parts, Pericarpium Papaveris 216 parts, Radix Ophiopogonis 108 parts, Flos Farfarae 324 parts,
Radix Asteris 108 parts, Semen Armeniacae Amarum 108 parts, Bulbus Lilii 108 parts, Bulbus Fritillariae Thunbergii 24 parts.Bulbus Lilii,
Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；The Rhizoma Anemarrhenae, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis
Secondary, collecting decoction, filter, filtrate is condensed into cream；Flos Farfarae, Radix Asteris ethanol heat back
Stream extracts three times；Semen Armeniacae Amarum deoils, and extracts secondary with alcohol heating reflux, united extraction liquid,
Reclaim ethanol, be condensed into cream.Above-mentioned two kinds of condensed creams are merged, adds fine powders such as Bulbus Lilii and auxiliary
Material is appropriate, mixing, makes granule, is dried, obtains dried object A.
The Chinese medicine composition of a kind of removing heat from the lung and dissipating phlegm relieving cough, relieving asthma the most according to claim 7
Preparation method, it is characterised in that: Bulbus Lilii, Bulbus Fritillariae Thunbergii is respectively crushed into fine powder, sieves；Know
Mother, Pericarpium Papaveris, Radix Scrophulariae, boiling Radix Ophiopogonis secondary, 3 hours for the first time, 1 is little for the second time
Time, collecting decoction, filter, filtrate is condensed into cream；Flos Farfarae, Radix Asteris add with 60% ethanol
Circumfluence distillation three times, 6 hours for the first time, 4 hours for the second time, 2 hours for the third time；Bitter
Semen Armeniacae Amarum deoils, and extracts secondary with 85% alcohol heating reflux, 3 hours for the first time, and for the second time 2
Hour, united extraction liquid, reclaims ethanol, is condensed into cream.Above-mentioned two kinds of condensed creams are merged,
Add fine powder and the right amount of auxiliary materials such as Bulbus Lilii, mixing, make granule, be dried, obtain dried object A.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410804360.7A CN105878713A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicinal composition with efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and preparation method of traditional Chinese medicinal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410804360.7A CN105878713A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicinal composition with efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and preparation method of traditional Chinese medicinal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105878713A true CN105878713A (en) | 2016-08-24 |
Family
ID=56701077
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410804360.7A Pending CN105878713A (en) | 2014-12-12 | 2014-12-12 | Traditional Chinese medicinal composition with efficacies of clearing lung and eliminating phlegm as well as relieving cough and asthma and preparation method of traditional Chinese medicinal composition |
Country Status (1)
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| CN (1) | CN105878713A (en) |
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2014
- 2014-12-12 CN CN201410804360.7A patent/CN105878713A/en active Pending
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Application publication date: 20160824 |