CN103656164A - Traditional Chinese medicine composition for nourishing yin, nourishing blood, tonifying heart and soothing nerves and preparation method thereof - Google Patents

Traditional Chinese medicine composition for nourishing yin, nourishing blood, tonifying heart and soothing nerves and preparation method thereof Download PDF

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CN103656164A
CN103656164A CN201210349079.XA CN201210349079A CN103656164A CN 103656164 A CN103656164 A CN 103656164A CN 201210349079 A CN201210349079 A CN 201210349079A CN 103656164 A CN103656164 A CN 103656164A
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parts
radix
chinese medicine
medicine composition
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刘萍
聂万达
游强臻
朱晓丹
刘伟
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LONGSHUNRONG PHARMACEUTICAL FACTORY TIANJIN ZHONGXIN PHARMACEUTICAL GROUP CO
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LONGSHUNRONG PHARMACEUTICAL FACTORY TIANJIN ZHONGXIN PHARMACEUTICAL GROUP CO
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Abstract

The invention discloses a traditional Chinese medicine composition for treating nourishing yin, nourishing the blood, tonifying the heart and soothing the nerves and a preparation method thereof, belonging to the field of modernization of traditional Chinese medicines. The active component of the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 200 parts of radix rehmanniae, 50 parts of ophiopogon root, 25 parts of tuckahoe, 25 parts of figwort, 50 parts of radix asparagi, 25 parts of dangshen, 50 parts of schisandra fruit, 50 parts of angelica, 25 parts of polygala root (prepared), 25 parts of balloonflower, 50 parts of spina date seed (stir-fried), 50 parts of shelled cedar seed, 25 parts of radix salviae miltiorrhizae, 25 parts of licorice (honey-roasted), 25 parts of Japanese sweetflag and 10 parts of cinnabar. The traditional Chinese medicine composition is characterized in that the preparation method of the reasonable and stable active component is obtained according to the research results of physicochemical properties and pharmacological actions of the components contained in the medicines. The medicine disclosed by the invention has the advantages of stable and controllable quality, obviously higher curative effect than the preparation formulations sold in the existing market, and smaller dose taken by the patient. The traditional Chinese medicine composition has obvious economic and social benefits.

Description

Chinese medicine composition of a kind of nourishing YIN and benefiting blood heart tonifying and tranquilizing and preparation method thereof
Technical field
The present invention relates to Chinese medicine composition of a kind of nourishing YIN and benefiting blood heart tonifying and tranquilizing and preparation method thereof, belong to modern Chinese traditional medicine field.
Background technology
Reinforcing the heart sheet nourishing YIN and benefiting blood, heart tonifying and tranquilizing.For cardiopalmus Mental fatigue, the insomnia forgetfulness of deficiency of YIN insufficiency of blood, constipation with dry stool, aphtha of the mouth and tongue, the few tongue of red tongue, thready and rapid pulse.The clinical chronic disease patient for insomnia forgetfulness.
When running into the disease of the mind uneasinesses such as nervous cardiopalmus, insomnia forgetfulness, doctor trained in Western medicine is treated mainly with tranquilizer and sleeping pill etc.; But the untoward reaction of these medicines is often larger, and may produce dependence effect.And the traditional Chinese medical science thinks that the pathogenic factor of insomnia is a lot, but nothing more than two kinds of deficiency and excesss.Wherein deficiency syndrome belong to deficiency of YIN-blood more, and the moon declines the excess of YANG and has difficulty in going to sleep.Prescription often also adopts the less medicine of successful and untoward reaction.Reinforcing the heart sheet is exactly the Chinese patent medicine that treatment cardiopalmus is nervous, insomnia is slept less.Mainly, with the ingredients of nourishing YIN and benefiting blood, be applicable to the treatment of the diseases such as insomnia and dreamful sleep, dysphoria, severe palpitation, hypomnesis.Treat the deficiency of YIN and uneasy method.Disease is seen palpitation and being susceptible to fright, forgetful insomnia, absentminded, dreaminess seminal emission, aphtha of the mouth and tongue, constipation due to dry stool, the few tongue of red tongue, thready and rapid pulse.
The prescription of reinforcing the heart sheet and method for making are: Radix Rehmanniae 200g, Radix Ophiopogonis 50g, Poria 25g, Radix Scrophulariae 25g, Radix Asparagi 50g, Radix Codonopsis 25g, Fructus Schisandrae Chinensis 50g, Radix Angelicae Sinensis 50g, Radix Polygalae (system) 25g, Radix Platycodonis 25g, Semen Ziziphi Spinosae (stir-fry) 50g, Semen Platycladi 50g, Radix Salviae Miltiorrhizae 25g, Radix Glycyrrhizae (processed with honey) 25g, Rhizoma Acori Graminei 25g, Cinnabaris 10g.Above ten Six-elements, Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction, filtered, and filtrate is concentrated into thick paste shape; Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, according to the percolation (17 pages of appendix) under fluid extract and extractum item, with 60% ethanol, make solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into thick paste shape; Get above-mentioned fine powder and thick paste and mix, granulation, dry, in flakes, sugar coating, obtains in compacting.
Summary of the invention
First technical problem that the present invention will solve is to provide a kind of Chinese medicine composition of nourishing YIN and benefiting blood heart tonifying and tranquilizing.
Another technical problem that the present invention will solve is to provide the preparation method of above-mentioned Chinese medicine composition.
For achieving the above object, the present invention by the following technical solutions;
A Chinese medicine composition for nourishing YIN and benefiting blood heart tonifying and tranquilizing, its active component is made by the raw material of following parts by weight: 200 parts of Radix Rehmanniae, 50 parts of Radix Ophiopogonis, 25 parts, Poria, 25 parts of Radix Scrophulariaes, 50 parts of Radix Asparagis, 25 parts of Radix Codonopsis, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Angelicae Sinensis, 25 parts of Radix Polygalaes (system), 25 parts of Radix Platycodoniss, 50 parts of Semen Ziziphi Spinosaes (stir-fry), 50 parts of Semen Platycladi, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts, Radix Glycyrrhizae (processed with honey), 25 parts of Rhizoma Acori Graminei, 10 parts, Cinnabaris.
Described active component adopts following method to prepare:
1, by proportioning raw materials, take each raw material; ; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction, filtered, and filtrate is concentrated into thick paste shape; Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with 60% ethanol, make solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into thick paste shape; Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
2, by proportioning raw materials, take each raw material; Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
Described pharmaceutical composition also contains the acceptable adjuvant of pharmaceutics.
The acceptable adjuvant of described pharmaceutics is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, Carboxymethyl cellulose sodium, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and sodium sulfite.
The dosage form of described Chinese medicine composition is peroral dosage form, includes but not limited to pill, tablet, capsule or oral liquid.The selection of dosage form and the consumption of adjuvant all belong to prior art.
A kind of preparation method of Chinese medicine composition of nourishing YIN and benefiting blood heart tonifying and tranquilizing:
Take 200 parts of Radix Rehmanniae, 50 parts of Radix Ophiopogonis, 25 parts, Poria, 25 parts of Radix Scrophulariaes, 50 parts of Radix Asparagis, 25 parts of Radix Codonopsis, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Angelicae Sinensis, 25 parts of Radix Polygalaes (system), 25 parts of Radix Platycodoniss, 50 parts of Semen Ziziphi Spinosaes (stir-fry), 50 parts of Semen Platycladi, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts, Radix Glycyrrhizae (processed with honey), 25 parts of Rhizoma Acori Graminei, 10 parts, Cinnabaris.Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction, filtered, and filtrate is concentrated into thick paste shape; Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with 60% ethanol, make solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into thick paste shape; Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
Preferred preparation method is: by proportioning raw materials, take each raw material; Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
A preparation for the Chinese medicine composition of nourishing YIN and benefiting blood heart tonifying and tranquilizing, said preparation adds the acceptable adjuvant of pharmaceutics with above-mentioned active constituents of medicine, makes the acceptable dosage form of pharmaceutics.While utilizing the various dosage form of the required medicine of active fraction preparation of the Chinese medicine composition that the present invention obtains, can be according to the conventional production method preparation in pharmaceutics field.As this active component is mixed with one or more carriers, then make corresponding dosage form.
Advantage of the present invention is: the present invention uses theory of Chinese medical science analysis prescription to form, and according to the physicochemical property of each flavour of a drug ingredient and pharmacological action, research has obtained the preparation method of reasonable, stable active component.Adopt technical scheme of the present invention, on dutyly gone out pharmaceutical preparation stable and controllable for quality, that curative effect is compared with existing commercially available dosage form and significantly improved, patient's taking dose reduces, there is significant economic and social benefit.
Describe by the following examples technical solution of the present invention in detail, with this, do not limit practical range of the present invention.
The specific embodiment
Embodiment 1: prepare Chinese medicine extract
One, prescription: Radix Rehmanniae 200g, Radix Ophiopogonis 50g, Poria 25g, Radix Scrophulariae 25g, Radix Asparagi 50g, Radix Codonopsis 25g, Fructus Schisandrae Chinensis 50g, Radix Angelicae Sinensis 50g, Radix Polygalae (system) 25g, Radix Platycodonis 25g, Semen Ziziphi Spinosae (stir-fry) 50g, Semen Platycladi 50g, Radix Salviae Miltiorrhizae 25g, Radix Glycyrrhizae (processed with honey) 25g, Rhizoma Acori Graminei 25g, Cinnabaris 10g.
Two, method for making:
Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A and amount to 267g.
Embodiment 2: prepare Chinese medicine extract
One, prescription: Radix Rehmanniae 130kg, Radix Ophiopogonis 32.5kg, Poria 16.25kg, Radix Scrophulariae 16.25kg, Radix Asparagi 32.5kg, Radix Codonopsis 16.25kg, Fructus Schisandrae Chinensis 32.5kg, Radix Angelicae Sinensis 32.5kg, Radix Polygalae (system) 16.25kg, Radix Platycodonis 16.25kg, Semen Ziziphi Spinosae (stir-fry) 32.5kg, Semen Platycladi 32.5kg, Radix Salviae Miltiorrhizae 16.25g, Radix Glycyrrhizae (processed with honey) 16.25kg, Rhizoma Acori Graminei 16.25kg, Cinnabaris 6.5kg.
Two, method for making:
Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A and amount to 173.6kg.
Embodiment 3: prepare tablet
The active component 100g that embodiment 1 obtains, adds microcrystalline Cellulose 40g, cross-linked pvp 7g, and tabletting, obtains tablet, every heavy 0.35g.
Embodiment 4: prepare capsule
The active component 1000g that embodiment 1 obtains, adds starch 250g, and encapsulating capsule, obtains capsule, every heavy 0.50g.
Embodiment 5: zoopery
One, materials and methods:
ANSHEN BUXIN WAN (lot number 100807), Pingshan, Foochow pharmaceutical factory provides.
Sedative jujube kernel capsule (lot number 110427), the Chongqing pharmaceutical factory of traditional Chinese medicine provides.
Reinforcing the heart sheet (lot number 110816), Longshunrong Pharmaceutical Factory, Tianjin Zhongxin Pharmaceutical Group Co., Ltd's product.
Animal: ICR mice, 18-22g, is provided by Beijing Vital River Experimental Animals Technology Co., Ltd., credit number: SCXK (capital) 2002-2003.
Get 60 of healthy ICR mices, divide at random 6 groups, 10 every group.Test is established: matched group (giving normal saline 20ml/kg); Extract high and low dose group, reinforcing the heart sheet high and low dose group; Positive controls sedative jujube kernel capsule 0.4g/kg.All with normal saline, be made into 20ml suspension, by body weight 0.2ml/10g to mice ig.After administration 50 minutes, mice is put in the mice activity inventory box of the multiplex instrument connection of pharmacology physiology, adapts to after 3 minutes, starts the movable number of times of mice in record 5 pulmonary abscess.
Two, the results are shown in Table 1.
Table 1
Group Dosage (g/kg) 5 minutes movable number of times
Matched group 105.3±39.5
Extract high dose group 7.2 48.7±21.7***
Extract low dose group 1.8 88.3±31.8
Reinforcing the heart sheet 7.2 62.2±24.3**
Reinforcing the heart sheet 1.8 91.0±23.4
Sedative jujube kernel capsule group 0.4 60.1±16.9**
T check: compare * * p < 0.01 with matched group, * * * p < 0.001, illustrate that extract and tablet high dose and sedative jujube kernel capsule all have sedation, and sedation is better than reinforcing the heart sheet.

Claims (8)

1. a Chinese medicine composition for nourishing YIN and benefiting blood heart tonifying and tranquilizing, its active component is made by the raw material of following parts by weight: 200 parts of Radix Rehmanniae, 50 parts of Radix Ophiopogonis, 25 parts, Poria, 25 parts of Radix Scrophulariaes, 50 parts of Radix Asparagis, 25 parts of Radix Codonopsis, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Angelicae Sinensis, 25 parts of Radix Polygalaes (system), 25 parts of Radix Platycodoniss, 50 parts of Semen Ziziphi Spinosaes (stir-fry), 50 parts of Semen Platycladi, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts, Radix Glycyrrhizae (processed with honey), 25 parts of Rhizoma Acori Graminei, 10 parts, Cinnabaris.
2. a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing according to claim 1, is characterized in that described active component adopts following method to prepare: Cinnabaris water flies or be ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction, filtered, and filtrate is concentrated into thick paste shape; Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with 60% ethanol, make solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into thick paste shape; Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
3. a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing according to claim 2, is characterized in that: Cinnabaris water flies or be ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
4. according to a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing described in any one in claims 1 to 3, it is characterized in that: affiliated medicine also contains the acceptable adjuvant of pharmaceutics.
5. a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing according to claim 4, is characterized in that: the acceptable adjuvant of described pharmaceutics is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, Carboxymethyl cellulose sodium, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and sodium sulfite.
6. a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing according to claim 4, is characterized in that: the dosage form of described Chinese medicine composition is peroral dosage form, comprises pill, tablet, capsule or oral liquid.
7. a preparation method for the treatment of the Chinese medicine composition of nourishing YIN and benefiting blood heart tonifying and tranquilizing, is characterized in that: take 200 parts of Radix Rehmanniae, 50 parts of Radix Ophiopogonis, 25 parts, Poria, 25 parts of Radix Scrophulariaes, 50 parts of Radix Asparagis, 25 parts of Radix Codonopsis, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Angelicae Sinensis, 25 parts of Radix Polygalaes (system), 25 parts of Radix Platycodoniss, 50 parts of Semen Ziziphi Spinosaes (stir-fry), 50 parts of Semen Platycladi, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts, Radix Glycyrrhizae (processed with honey), 25 parts of Rhizoma Acori Graminei, 10 parts, Cinnabaris.Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, 2 hours for the first time, 1.5 hours for the second time, collecting decoction, filtered, and filtrate is concentrated into thick paste shape; Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with 60% ethanol, make solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into thick paste shape; Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
8. a kind of Chinese medicine composition for the treatment of nourishing YIN and benefiting blood heart tonifying and tranquilizing according to claim 1 according to claim 7, is characterized in that: take 200 parts of Radix Rehmanniae, 50 parts of Radix Ophiopogonis, 25 parts, Poria, 25 parts of Radix Scrophulariaes, 50 parts of Radix Asparagis, 25 parts of Radix Codonopsis, 50 parts of Fructus Schisandrae Chinensis, 50 parts of Radix Angelicae Sinensis, 25 parts of Radix Polygalaes (system), 25 parts of Radix Platycodoniss, 50 parts of Semen Ziziphi Spinosaes (stir-fry), 50 parts of Semen Platycladi, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts, Radix Glycyrrhizae (processed with honey), 25 parts of Rhizoma Acori Graminei, 10 parts, Cinnabaris.Cinnabaris water flies or is ground into impalpable powder; Poria, Radix Platycodonis, Radix Glycyrrhizae powder are broken into fine powder, sieve; Decoct with water Radix Rehmanniae, Radix Codonopsis, Radix Asparagi, Radix Ophiopogonis secondary, decoct 2 hours for the first time with 10 times of water gagings, decoct 1.5 hours for the second time with 8 times of water gagings, collecting decoction, filters, and filtrate is concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Eight tastes such as all the other Semen Platycladi, are ground into coarse powder, with the concentration of volume percent of 8 times of amounts, are that 60% ethanol is made solvent, flood after 24 hours and carry out percolation, collect the liquid of filtering, and reclaim ethanol, and are concentrated into the thick paste of relative density 1.20-1.30 (55 ℃); Get above-mentioned fine powder and thick paste and mix, granulation, dry, obtain dry thing A.
CN201210349079.XA 2012-09-20 2012-09-20 Traditional Chinese medicine composition for nourishing yin, nourishing blood, tonifying heart and soothing nerves and preparation method thereof Pending CN103656164A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104206597A (en) * 2014-09-05 2014-12-17 青岛恒波仪器有限公司 Schisandra chinensis health tea capable of relieving lung and kidney yin deficiency symptoms and preparation method of schisandra chinensis heath tea
CN104825839A (en) * 2015-04-30 2015-08-12 刘德刚 Tranquilizing traditional Chinese medicine
CN105309882A (en) * 2014-07-10 2016-02-10 天津港保税区爱信食品有限公司 Making method of heart nourishing and mind tranquillizing cooked rice or parboiled rice

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105309882A (en) * 2014-07-10 2016-02-10 天津港保税区爱信食品有限公司 Making method of heart nourishing and mind tranquillizing cooked rice or parboiled rice
CN104206597A (en) * 2014-09-05 2014-12-17 青岛恒波仪器有限公司 Schisandra chinensis health tea capable of relieving lung and kidney yin deficiency symptoms and preparation method of schisandra chinensis heath tea
CN104825839A (en) * 2015-04-30 2015-08-12 刘德刚 Tranquilizing traditional Chinese medicine

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Application publication date: 20140326