CN105853318B - A kind of toothpaste and preparation method thereof - Google Patents

A kind of toothpaste and preparation method thereof Download PDF

Info

Publication number
CN105853318B
CN105853318B CN201610463770.9A CN201610463770A CN105853318B CN 105853318 B CN105853318 B CN 105853318B CN 201610463770 A CN201610463770 A CN 201610463770A CN 105853318 B CN105853318 B CN 105853318B
Authority
CN
China
Prior art keywords
toothpaste
siraitia grosvenorii
extract
fine powder
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610463770.9A
Other languages
Chinese (zh)
Other versions
CN105853318A (en
Inventor
温剑文
李翠兰
谭叶倩
杨洪元
蒋向军
蒋臻韬
梁海耀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUILIN SUNNYLIGE MODERN BIOTECHNOLOGY Inc
Original Assignee
GUILIN SUNNYLIGE MODERN BIOTECHNOLOGY Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUILIN SUNNYLIGE MODERN BIOTECHNOLOGY Inc filed Critical GUILIN SUNNYLIGE MODERN BIOTECHNOLOGY Inc
Priority to CN201610463770.9A priority Critical patent/CN105853318B/en
Publication of CN105853318A publication Critical patent/CN105853318A/en
Application granted granted Critical
Publication of CN105853318B publication Critical patent/CN105853318B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

The present invention provides a kind of toothpaste, the toothpaste includes following components:Siraitia grosvenorii fine powder 15 25%, Fructus Monordicae extract extract powder 5 10%, coconut oil 20 30%, guar gum 10 20%, xanthans 15 25%, sodium benzoate 0.1 0.8%, surplus is deionized water.The toothpaste of the present invention does not need to additionally add abrasive material, sweetener, foaming agent, aromatic, and safety is good, and the effects that can play antibacterial anti hemorrhagic anti-inflammatory.The toothpaste method is prepared the present invention also provides a kind of, the method includes:1) Siraitia grosvenorii micropowders and Fructus Monordicae extract extract powder are prepared;2) coconut oil, guar gum, xanthans are proportionally added into emulsification pot, then addition deionized water, which is sufficiently mixed, is formed uniformly original mixture;3) Siraitia grosvenorii micropowders, Fructus Monordicae extract extract powder and sodium benzoate are added in the mixture into step 2) and is uniformly mixed, lotion is made in vacuum stirring.

Description

A kind of toothpaste and preparation method thereof
Technical field
The present invention relates to field of toothpaste, in particular to a kind of toothpaste and preparation method thereof.
Background technology
Toothpaste is necessary dental care products in people's daily life.In recent years, some are nontoxic, there is medical treatment to protect The Chinese herbal toothpaste of strong effect is increasingly subject to market favor, according to statistics, have the Chinese herbal toothpastes of national characters at present in occupation of 40%~50% domestic market share.
The Chinese herbal medicine usually added in Chinese herbal toothpaste is mostly the medicinal herb components with anti-inflammatory, whitening function, in addition to The required abrasive material of addition toothpaste itself, sweetener, foaming agent and aromatic are also needed outside medicinal herb components, therefore ingredient is very multiple Miscellaneous, various chemical addition agents are also easily so that adverse reactions such as in itself medicinal herb components are modified, go bad.
Siraitia grosvenorii is the fruit that Curcurbitaceae Siraitia grosvenorii belongs to perennial liana, is the medicine-food two-purpose of health ministry identification Plant.Siraitia grosvenorii is rich in sweet tea glycosides, flavones, vitamin, protein, amino acid, mannitol, scavenger substances, lot of trace member The active ingredients such as element have kobadrin, antibacterial shield tooth, anti-inflammatory and antalgic, Scavenger of ROS, peroxynitrite decomposition lipid and other effects. Siraitia grosvenorii root tuber bitter rich in ingredients such as starch, protein, flavones, Anthraquinones, has very strong antimicrobial and anti-inflammation efficacy.
Therefore, toothpaste is prepared using Siraitia grosvenorii and its extract, is rationally set to play health-care effect using it and pass through Count preparation process, avoid additionally adding various auxiliary materials such as abrasive material, sweetener, foaming agent, aromatic etc. be for consumers Meaningful.
Invention content
The first object of the present invention is to provide a kind of toothpaste, and the toothpaste is with Siraitia grosvenorii fine powder and Fructus Monordicae extract Extract powder is main component, can effectively anti-inflammatory, antibacterial, shield tooth, cleaning oral cavity.
The second object of the present invention is to provide a kind of preparation method of the toothpaste, this method simple production process, and The health care ingredient of Siraitia grosvenorii can be retained to greatest extent.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme:
One aspect of the present invention is related to a kind of toothpaste, which is characterized in that the toothpaste includes following components:Siraitia grosvenorii is thin Powder 15-25%, Fructus Monordicae extract extract powder 5-10%, coconut oil 20-30%, guar gum 10-20%, xanthans 15-25%, Sodium benzoate 0.1-0.8%, surplus are deionized water, wherein, the sodium benzoate is the food grade sodium benzoate of national standard.
The toothpaste of the present invention is using the full fruit of new fresh fructus momordicae as raw material, is equipped with the auxiliary materials tune such as coconut oil, xanthans, guar gum With into.Its with the substances such as lithocyte, the cellulose in Siraitia grosvenorii can replace conventional toothpaste in calcium carbonate, silica, The industrial chemicals such as calcium monohydrogen phosphate are as abrasive material, and its scale removal works well.In addition, Siraitia grosvenorii has the sweet tea of high sugariness in itself Glucoside, and itself has fragrance, and therefore, the addition of Siraitia grosvenorii fine powder, which can also substitute, needs sweetener to be added in general toothpaste And aromatic.On the other hand, therefore the microstructure of Siraitia grosvenorii fine powder, easily blisters into concrete dynamic modulus shape, can play foaming The effect of agent.It can be seen that it is of the invention by adding arhat fruit component, and eliminating in a variety of ordinary toothpastes needs to be addedization Product component, safety greatly improve, and harm caused by toothpaste can be accidentally gulped down to avoid children, and suitable various people make With.
Preferably, the component of the toothpaste is by mass percentage:Siraitia grosvenorii particle 18-22%, Fructus Monordicae extract Extract powder 5-7%, coconut oil 20-25%, guar gum 13-16%, xanthans 19-22%, sodium benzoate 0.3-0.4%, surplus For deionized water, wherein, the sodium benzoate is the food grade sodium benzoate of national standard.
Preferably, the granularity of the Siraitia grosvenorii fine powder is >=120 mesh.
Preferably, the granularity of the Fructus Monordicae extract extract powder is >=120 mesh.
It can promote disengaging for active material in Siraitia grosvenorii using the micropowders of high mesh number, play its health-care efficacy.
Another aspect of the present invention is related to the preparation method of the toothpaste, the described method comprises the following steps:
1) Siraitia grosvenorii fine powder and Fructus Monordicae extract extract powder are prepared;
2) coconut oil, guar gum, xanthans are proportionally added into emulsification pot, then add in deionized water and be sufficiently mixed Even formation original mixture;
3) Siraitia grosvenorii fine powder, Fructus Monordicae extract extract powder and sodium benzoate are added in simultaneously in the mixture into step 2) It is uniformly mixed, lotion is made in vacuum stirring.
Step of the present invention is relatively simple, easy to implement, and cost is relatively low, and raw material sources are extensive, also, side according to the invention Method can farthest preserve the activity and health-care efficacy of Siraitia grosvenorii ingredient.
Preferably, the Siraitia grosvenorii fine powder in the step 1) is prepared by following steps:Use fresh sieve of sterile water wash Chinese fruit, rear microwave drying and ultramicro grinding into >=120 mesh micropowders, wherein the Siraitia grosvenorii is arhat of no seed without insect pest Fruit.
When selecting fruit, the Siraitia grosvenorii of low glucoside, moderate maturity is chosen, the Siraitia grosvenorii fine powder after microwave drying is ground can be With fully discharging its bioactive substance during other components compatibility.
Preferably, microwave drying temperature≤75 DEG C, vacuum degree are -0.08~-0.098Mpa.
Preferably, the Fructus Monordicae extract extract powder in the step 1) through the following steps that prepare:
A) new fresh fructus momordicae is chosen, coarse crushing is carried out after cleaning, is carried afterwards using water;
B) water extract is concentrated, medicinal extract is formed, using being spray-dried and fine powder is made.
Preferably, in the step a), by the mesh of Siraitia grosvenorii coarse crushing to granularity >=20,2-4 times of water is added in, at 50-80 DEG C Lower extraction 2-3 hours.
Preferably, it is stirred under vacuum in the step 3) and is carried out in vacuum emulsifying machine, mixing time is 5-10 minutes.
Compared with prior art, beneficial effects of the present invention are:
(1) toothpaste components such as abrasive material, sweetener, foaming agent, aromatic used in the present invention are the composition of Siraitia grosvenorii Ingredient, other used auxiliary materials are also mainly derived from biology and to commonly use raw material in food medicine, and safety is good, can be to avoid Harm caused by children accidentally gulp down toothpaste, is suitble to various people to use.
(2) Siraitia grosvenorii fine powder, the Fructus Monordicae extract extract powder selected in the present invention, production technology are protected to greatest extent The effect of having stayed the health care ingredient of Siraitia grosvenorii, having made Siraitia grosvenorii anti-inflammatory, antibacterial, shield tooth, cleaning oral cavity is fully played.
(3) raw material sources of Siraitia grosvenorii toothpaste of the present invention are wide, simple production process, and production cost is low.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific Condition person, the condition suggested according to normal condition or manufacturer carry out.Reagents or instruments used without specified manufacturer is The conventional products that can be obtained by commercially available purchase.
Embodiment 1
Siraitia grosvenorii toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Siraitia grosvenorii toothpaste
The preparation of fresh fructus momordicae fine powder:Select that low sweet tea glucoside, maturity be moderate, seedless monordica grosvenori of no disease and pests harm, through sterile Water rinses repeatedly dries surface water, and after microwave drying, the micropowders of ultramicro grinding into 140-160 mesh preserve standby at low temperature With.
It is prepared by Fructus Monordicae extract extract powder:Choose new fresh fructus momordicae, cleaning removes surface irregularities, and coarse crushing is into 20 purposes Grain, adds water to be extracted 2 hours at 50 DEG C, concentrates and is spray dried to fine powder and saves backup at low temperature.
(2) formula composition of Siraitia grosvenorii toothpaste:Siraitia grosvenorii fine powder 18%, Fructus Monordicae extract extract powder 7%, coconut oil 20%, guar gum 13%, xanthans 22%, food-grade sodium benzoate 0.4%, remaining is deionized water.
(3) preparation of Siraitia grosvenorii toothpaste:First coconut oil, guar gum, xanthans are proportionally added into add in emulsification pot and be gone Ionized water, which is sufficiently mixed, is formed uniformly original mixture, and Siraitia grosvenorii fine powder, arhat are then proportionally added into original mixture Berry extract extract powder, food-grade sodium benzoate are simultaneously uniformly mixed, and are stirred 5 minutes in vacuum emulsifying machine and lotion is made, filling Enter multiple tube.
Embodiment 2
Siraitia grosvenorii toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Siraitia grosvenorii toothpaste
The preparation of fresh fructus momordicae fine powder:Select that low sweet tea glucoside, maturity be moderate, seedless monordica grosvenori of no disease and pests harm, through sterile Water rinses repeatedly dries surface water, and after microwave drying, the micropowders of ultramicro grinding into 140-160 mesh preserve standby at low temperature With.
It is prepared by Fructus Monordicae extract extract powder:Choose new fresh fructus momordicae, cleaning removes surface irregularities, and coarse crushing is into 20 purposes Grain, adds water to be extracted 3 hours at 80 DEG C, concentrates and is spray dried to fine powder and saves backup at low temperature.
(2) formula composition of Siraitia grosvenorii toothpaste:Siraitia grosvenorii fine powder 22%, Fructus Monordicae extract extract powder 5%, coconut oil 25%, guar gum 16%, xanthans 19%, food-grade sodium benzoate 0.3%, remaining is deionized water.
(3) preparation of Siraitia grosvenorii toothpaste:First coconut oil, guar gum, xanthans are proportionally added into add in emulsification pot and be gone Ionized water, which is sufficiently mixed, is formed uniformly original mixture, and Siraitia grosvenorii fine powder, arhat are then proportionally added into original mixture Berry extract extract powder, food-grade sodium benzoate are simultaneously uniformly mixed, and are stirred 10 minutes in vacuum emulsifying machine and lotion is made, filling Enter multiple tube.
Embodiment 3
Siraitia grosvenorii toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Siraitia grosvenorii toothpaste
The preparation of fresh fructus momordicae fine powder:Select that low sweet tea glucoside, maturity be moderate, seedless monordica grosvenori of no disease and pests harm, through sterile Water rinses repeatedly dries surface water, and after microwave drying, the micropowders of ultramicro grinding into 140-160 mesh preserve standby at low temperature With.
It is prepared by Fructus Monordicae extract extract powder:Choose new fresh fructus momordicae, cleaning removes surface irregularities, and coarse crushing is into 20 purposes Grain, adds water to be extracted 2 hours at 50 DEG C, concentrates and is spray dried to fine powder and saves backup at low temperature.
(2) formula composition of Siraitia grosvenorii toothpaste:Siraitia grosvenorii fine powder 15%, Fructus Monordicae extract extract powder 5%, coconut oil 20%, guar gum 10%, xanthans 15%, food-grade sodium benzoate 0.1%, remaining is deionized water.
(3) preparation of Siraitia grosvenorii toothpaste:First coconut oil, guar gum, xanthans are proportionally added into add in emulsification pot and be gone Ionized water, which is sufficiently mixed, is formed uniformly original mixture, and Siraitia grosvenorii fine powder, arhat are then proportionally added into original mixture Berry extract extract powder, food-grade sodium benzoate are simultaneously uniformly mixed, and are stirred 5 minutes in vacuum emulsifying machine and lotion is made, filling Enter multiple tube.
Embodiment 4
Siraitia grosvenorii toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Siraitia grosvenorii toothpaste
The preparation of fresh fructus momordicae fine powder:Select that low sweet tea glucoside, maturity be moderate, seedless monordica grosvenori of no disease and pests harm, through sterile Water rinses repeatedly dries surface water, and after microwave drying, the micropowders of ultramicro grinding into 140-160 mesh preserve standby at low temperature With.
It is prepared by Fructus Monordicae extract extract powder:It chooses the cleaning of fresh fresh fructus momordicae and removes surface irregularities, coarse crushing is into 20 purposes Particle adds water to be extracted 2 hours at 50 DEG C, concentrates and is spray dried to fine powder and saves backup at low temperature.
(2) formula composition of Siraitia grosvenorii toothpaste:Siraitia grosvenorii fine powder 25%, Fructus Monordicae extract extract powder 10%, coconut oil 30%, guar gum 20%, xanthans 25%, food-grade sodium benzoate 0.8%, remaining is deionized water.
(3) preparation of Siraitia grosvenorii toothpaste:First coconut oil, guar gum, xanthans are proportionally added into add in emulsification pot and be gone Ionized water, which is sufficiently mixed, is formed uniformly original mixture, and Siraitia grosvenorii fine powder, arhat are then proportionally added into original mixture Berry extract extract powder, food-grade sodium benzoate are simultaneously uniformly mixed, and are stirred 5 minutes in vacuum emulsifying machine and lotion is made, filling Enter multiple tube.
Usage experience is evaluated
50 volunteers are chosen, it is asked to be brushed daily using the toothpaste prepared in the embodiment of the present invention 1 in morning in 15 days Tooth carries out questionnaire survey after 5 minutes, 15 days to 50 volunteers, please its scale removal, fresh breath and use for toothpaste of the present invention Experience and evaluated (including fragrance, sugariness etc.), conclusion is divided into satisfied and dissatisfied, and the result for being satisfied with number and satisfaction rate is as follows Shown in table:
Scale removal Fresh breath Use feeling
It is satisfied with number 42 48 43
Satisfaction rate 84% 96% 86%
Siraitia grosvenorii toothpaste usage experience is evaluated
Hemostasis and anti-inflammation application case
Case 1
Zhang, 25 years old, people from hazard prevention, bleeding gums symptoms last 3 years happened occasionally, and attempts various Chinese herbal medicine teeth Cream is brushed teeth, and is had no result.Using the Siraitia grosvenorii toothpaste of the present invention from June, 2015, bleeding gums symptom is improved after 10 days, and Adhere to that the toothpaste using the present invention is brushed teeth gum not normal condition bleed bottom again so far.Zhang has broken away from the tired of bleeding gums from this It disturbs.
Case 2
Slowly certain, 29 years old, during which Hefei ,Anhui people from city, bleeding gums symptoms last 7 years often occurs, attempts various Chinese and Western Medicine toothpaste, which is brushed teeth, is showed no improvement.In August, 2015 plays the Siraitia grosvenorii toothpaste using the present invention, and bleeding gums symptom obtains after 13 days Improve, and adhere to that the toothpaste using the present invention is brushed teeth gum not normal condition bleed bottom again so far.Slowly certain has broken away from tooth from this The puzzlement of oulorrhagia.
Case 3
Lee, 40 years old, people from Beijing suffered from periodontitis 1 year, deep to be perplexed by swelling and aching of gum.This hair is used from April, 2015 Bright toothpaste, after a week swelling and aching of gum phenomenon be eased, adhere to using the present invention toothpaste brush teeth daily twice, swelling and aching of gum Phenomenon is clearly better, and gradually fully recovers.Toothache puzzlement is broken away from from this.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that without departing substantially from the present invention's Many other change and modification can be made in the case of spirit and scope.It is, therefore, intended that in the following claims Including belonging to all such changes and modifications in the scope of the invention.

Claims (10)

1. a kind of toothpaste, which is characterized in that the toothpaste includes following components:Siraitia grosvenorii fine powder 15-25%, Fructus Monordicae extract Extract powder 5-10%, coconut oil 20-30%, guar gum 10-20%, xanthans 15-25%, sodium benzoate 0.1-0.8%, surplus For deionized water.
2. toothpaste according to claim 1, which is characterized in that the component of the toothpaste is by mass percentage:Arhat Fruit fine powder 18-22%, Fructus Monordicae extract extract powder 5-7%, coconut oil 20-25%, guar gum 13-16%, xanthans 19- 22%, sodium benzoate 0.3-0.4%, surplus is deionized water.
3. toothpaste according to claim 1, which is characterized in that the mesh of the granularity of the Siraitia grosvenorii fine powder >=140.
4. toothpaste according to claim 1, which is characterized in that the mesh of the granularity of the Fructus Monordicae extract extract powder >=120.
5. a kind of method for preparing the toothpaste in claim 1-4 described in any one, the described method comprises the following steps:
1) Siraitia grosvenorii fine powder and Fructus Monordicae extract extract powder are prepared;
2) coconut oil, guar gum, xanthans are proportionally added into emulsification pot, then add in deionized water and be sufficiently mixed uniform shape Into original mixture;
3) Siraitia grosvenorii fine powder, Fructus Monordicae extract extract powder and sodium benzoate are added in the mixture into step 2) and is mixed Uniformly, it is stirred under vacuum and lotion is made.
6. according to the method described in claim 5, it is characterized in that, the Siraitia grosvenorii fine powder in the step 1) passes through following steps It prepares:Using the new fresh fructus momordicae of sterile water wash, rear microwave drying is simultaneously ground into the targeted fine powder of granularity >=120, wherein sieve Chinese fruit is Siraitia grosvenorii of no seed without insect pest.
7. according to the method described in claim 6, it is characterized in that, microwave drying temperature≤75 DEG C, vacuum degree are -0.08 To -0.098Mpa.
8. according to the method described in claim 5, it is characterized in that, the Fructus Monordicae extract extract powder in the step 1) is logical Cross following steps preparation:
A) new fresh fructus momordicae is chosen, coarse crushing is carried out after cleaning, is carried afterwards using water;
B) water extract is concentrated, medicinal extract is formed, using being spray-dried and fine powder is made.
9. according to the method described in claim 8, it is characterized in that, in the step a), by Siraitia grosvenorii coarse crushing to granularity >=20 Mesh adds in 2-4 times of water, is extracted 2-3 hours at 50-80 DEG C.
10. it according to the method described in claim 5, it is characterized in that, is stirred under vacuum in vacuum emulsifying machine in the step 3) It carries out, mixing time is 5-10 minutes.
CN201610463770.9A 2016-06-23 2016-06-23 A kind of toothpaste and preparation method thereof Active CN105853318B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610463770.9A CN105853318B (en) 2016-06-23 2016-06-23 A kind of toothpaste and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610463770.9A CN105853318B (en) 2016-06-23 2016-06-23 A kind of toothpaste and preparation method thereof

Publications (2)

Publication Number Publication Date
CN105853318A CN105853318A (en) 2016-08-17
CN105853318B true CN105853318B (en) 2018-07-06

Family

ID=56654884

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610463770.9A Active CN105853318B (en) 2016-06-23 2016-06-23 A kind of toothpaste and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105853318B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109803728A (en) * 2016-10-17 2019-05-24 高露洁-棕榄公司 The oral care composition of appearance and form with enhancing
CN108670904A (en) * 2018-07-03 2018-10-19 海南馨原贸易有限公司 A kind of coconut oil VC toothpaste and preparation method thereof
CN109464376A (en) * 2018-12-14 2019-03-15 淮阴工学院 It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive
CN115282107A (en) * 2022-08-23 2022-11-04 广西壮族自治区药用植物园 Compound traditional Chinese medicine toothpaste and preparation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101147751A (en) * 2006-09-19 2008-03-26 周英 Method for extracting biologically active component from momordica grosvenori plant
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof
CN104958225A (en) * 2015-07-24 2015-10-07 大连民族大学 Cherry toothpaste and preparation method thereof
CN105596260A (en) * 2016-01-29 2016-05-25 海南宇星日用化工股份有限公司 Coconut toothpaste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101147751A (en) * 2006-09-19 2008-03-26 周英 Method for extracting biologically active component from momordica grosvenori plant
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof
CN104958225A (en) * 2015-07-24 2015-10-07 大连民族大学 Cherry toothpaste and preparation method thereof
CN105596260A (en) * 2016-01-29 2016-05-25 海南宇星日用化工股份有限公司 Coconut toothpaste

Also Published As

Publication number Publication date
CN105853318A (en) 2016-08-17

Similar Documents

Publication Publication Date Title
CN105853318B (en) A kind of toothpaste and preparation method thereof
US20090317461A1 (en) Oral compositions effective for the treatment of oral cavity malodor associated with the consumption of odor-causing compounds
CN101822382A (en) Fruity tea polyphenol buccal tablet and preparation method thereof
TW201309338A (en) Oral care compositions
KR101985771B1 (en) Foaming solid formulation for mouthwash and preperation method thereof
US20020031481A1 (en) Stable herbal dentrifice
JPH08310931A (en) Inhibitor of glucosyltransferase and cleaning agent for oral cavity
CN110691583A (en) Oral composition
JP2007051096A (en) Composition for oral cavity
KR101395218B1 (en) Soap comprising wood-cultivated ginseng and manufacturing method thereof
KR101186631B1 (en) Oral Composition
KR101154500B1 (en) Composition for oral
KR101793822B1 (en) Composition of toothpaste containing extract of euphorbia supina
CN107007502A (en) The oral care composition of noresidue sense
CN108601369B (en) Chewing gum composition using hericium erinaceus extract and cordycepin and preparation method thereof
KR101731420B1 (en) natural soap powder and a manufacturing method
WO2023164863A1 (en) Deep cleaning chewing gum
CN103695215B (en) Licorice low-irritation skin-care perfumed soap
KR102220517B1 (en) Composition for whiting and improving skin wrinkle
JPS61229827A (en) Gum containing medicinal plant
KR102061610B1 (en) Oral cleansing composition containing peppermint oil
JP4585066B2 (en) Caries inhibitor, oral preparation and food and drink
KR20240056349A (en) Functional soap for preventing hair loss using clove and method for manufacturing thereof
KR20200029967A (en) Foaming solid formulation for mouthwash and preperation method thereof
JPH07258105A (en) Glucosyl transferase inhibitor, agent for oral cavity and food or drink

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
PE01 Entry into force of the registration of the contract for pledge of patent right
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: The invention relates to a toothpaste and a preparation method thereof

Effective date of registration: 20211124

Granted publication date: 20180706

Pledgee: Financing Company limited by guarantee of small and micro enterprises in Guilin

Pledgor: GUILIN ERASUN MODERN BIO-TECH Inc.

Registration number: Y2021450000048

PC01 Cancellation of the registration of the contract for pledge of patent right
PC01 Cancellation of the registration of the contract for pledge of patent right

Date of cancellation: 20221227

Granted publication date: 20180706

Pledgee: Financing Company limited by guarantee of small and micro enterprises in Guilin

Pledgor: GUILIN ERASUN MODERN BIO-TECH Inc.

Registration number: Y2021450000048

PE01 Entry into force of the registration of the contract for pledge of patent right
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: A toothpaste and its preparation method

Effective date of registration: 20221229

Granted publication date: 20180706

Pledgee: Financing Company limited by guarantee of small and micro enterprises in Guilin

Pledgor: GUILIN ERASUN MODERN BIO-TECH Inc.

Registration number: Y2022450000242