CN105853318A - Toothpaste and preparation method thereof - Google Patents
Toothpaste and preparation method thereof Download PDFInfo
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- CN105853318A CN105853318A CN201610463770.9A CN201610463770A CN105853318A CN 105853318 A CN105853318 A CN 105853318A CN 201610463770 A CN201610463770 A CN 201610463770A CN 105853318 A CN105853318 A CN 105853318A
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- fructus momordicae
- toothpaste
- extract
- powder
- fine powder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
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- Epidemiology (AREA)
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- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention provides toothpaste. The toothpaste is prepared from the following components: 15-25 percent of momordica grosvenori fine powder, 5-10 percent of Momordica grosvenori extract powder, 20-30 percent of coconut oil, 10-20 percent of guar gum, 15-25 percent of xanthan gum, 0.1-0.8 percent of sodium benzoate and the balance of deionized water. The toothpaste does not need extra addition of abrasive, a sweetening agent, a foaming agent and aromatic, has good safety, and has the effects of inhibiting bacteria, stopping bleeding, diminishing inflammation and the like. The invention further provides a method for preparing the toothpaste. The method comprises the following steps: (1) preparing momordica grosvenori ultra-fine powder and momordica grosvenori extract powder; (2) adding coconut oil, guar gum and xanthan gum into an emulsification pot according to a proportion, and sufficiently and uniformly mixing with the deionized water to form a primary mixture; and (3) adding the mixture in the step (2) into the momordica grosvenori ultra-fine powder, momordica grosvenori extract powder and sodium benzoate, uniformly mixing, and stirring in vacuum to prepare the toothpaste.
Description
Technical field
The present invention relates to field of toothpaste, in particular to a kind of toothpaste and preparation method thereof.
Background technology
Toothpaste is necessary dental care products in people's daily life.In recent years, some are nontoxic,
The Chinese herbal toothpaste with medical care effect is increasingly subject to market favor, according to statistics, has national special
The Chinese herbal toothpaste of color at present in occupation of 40%～50% domestic market share.
The Chinese herbal medicine generally added in Chinese herbal toothpaste mostly is the Chinese herbal medicine one-tenth with antiinflammatory, whitening function
Point, it also needs to add the required abrasive material of toothpaste itself, sweeting agent, foaming in addition to medicinal herb components
Agent and aromatic, therefore composition is extremely complex, and various chemical addition agents the most easily make medicinal herb components
There is the untoward reaction such as modified, rotten in itself.
Fructus Momordicae is the fruit that Cucurbitaceae Fructus Momordicae belongs to perennial liana, is health ministry identification
Medicine food dual purpose plant.Fructus Momordicae is rich in sweet glycosides, flavone, vitamin, protein, aminoacid, sweet
The dew effective ingredient such as alcohol, scavenger material, various trace elements, has relieving cough and expelling phlegm, antibacterial protects
The effects such as tooth, anti-inflammatory and antalgic, Scavenger of ROS, peroxynitrite decomposition lipid.Fructus Momordicae tuber bitter in the mouth,
The compositions such as rich in starch, protein, flavone, Anthraquinones, have the strongest antimicrobial and anti-inflammation efficacy.
Therefore, Fructus Momordicae and extract thereof is used to prepare toothpaste, in order to utilize it to play health-care effect also
By appropriate design preparation technology, it is to avoid extra add various adjuvants such as abrasive material, sweeting agent, foaming agent,
Aromatic etc. are highly significant for consumers.
Summary of the invention
The first object of the present invention is to provide a kind of toothpaste, and described toothpaste is with Fructus Momordicae micropowders
It is main component with Fructus Momordicae extract extract powder, it is possible to antiinflammatory effectively, antibacterial, tooth protection, cleaning
Oral cavity.
The second object of the present invention is to provide the preparation method of a kind of described toothpaste, and the method produces work
Skill is simple, and can retain the health care composition of Fructus Momordicae to greatest extent.
In order to realize the above-mentioned purpose of the present invention, spy by the following technical solutions:
One aspect of the present invention relates to a kind of toothpaste, it is characterised in that described toothpaste includes following group
Point: Fructus Momordicae micropowders 15-25%, Fructus Momordicae extract extract powder 5-10%, Oleum Cocois 20-30%,
Guar gum 10-20%, xanthan gum 15-25%, sodium benzoate 0.1-0.8%, surplus is deionized water, its
In, described sodium benzoate is the food grade sodium benzoate of national standard.
The toothpaste of the present invention is with new fresh Fructus Momordicae full fruit superfine powder as raw material, is equipped with Oleum Cocois, xanthan
The allotment of the adjuvant such as glue, guar gum forms.It is permissible with materials such as the stone cell in Fructus Momordicae, celluloses
Replace in conventional toothpaste using industrial chemicals such as calcium carbonate, silicon dioxide, calcium hydrogen phosphate as abrasive material, and
And its scale removal is respond well.Additionally, Fructus Momordicae itself has the sweet glycoside of high sugariness, and itself have
Fragrance, therefore, the addition of Fructus Momordicae micropowder can also substitute the sweeting agent needing to add in general toothpaste
And aromatic.On the other hand, the microstructure of Fructus Momordicae micropowder becomes concrete dynamic modulus shape, and therefore, it is easy
Bubble, the effect of foaming agent can be played.As can be seen here, the present invention by add Fructus Momordicae component,
And eliminating the chemical component needing to add in multiple ordinary toothpaste, its safety is greatly improved, and
And child can be avoided to gulp down the harm that toothpaste causes by mistake, it is suitable for various people and uses.
Preferably, the component of described toothpaste is by mass percentage: Fructus Momordicae microgranule 18-22%, sieve
The Chinese berry extract extract powder 5-7%, Oleum Cocois 20-25%, guar gum 13-16%, xanthan gum 19-22%,
Sodium benzoate 0.3-0.4%, surplus is deionized water, and wherein, described sodium benzoate is national standard
Food grade sodium benzoate.
Preferably, the granularity of described Fructus Momordicae micropowders is >=120 mesh.
Preferably, the granularity of described Fructus Momordicae extract extract powder is >=120 mesh.
The micropowders using high mesh number can promote disengaging of active substance in Fructus Momordicae, plays it and protects
Strong effect.
Another aspect of the present invention relates to the preparation method of described toothpaste, and described method includes following step
Rapid:
1) Fructus Momordicae micropowders and Fructus Momordicae extract extract powder are prepared；
2) Oleum Cocois, guar gum, xanthan gum are proportionally added in emulsifying pot, are subsequently adding deionization
Water is sufficiently mixed and is formed uniformly original mixture；
3) to step 2) in mixture in add Fructus Momordicae micropowders, Fructus Momordicae extract extractum
Powder and sodium benzoate mix homogeneously, vacuum stirring makes mastic.
Step of the present invention is relatively simple, it is easy to implementing, cost is relatively low, and raw material sources are extensive, and,
Method according to the present invention can farthest preserve activity and the health-care effect of Fructus Momordicae composition.
Preferably, described step 1) in Fructus Momordicae micropowders prepared by following steps: use nothing
Bacterium water cleans new fresh Fructus Momordicae, and rear microwave drying superfine powder be broken into >=micropowders of 120 mesh, wherein
Described Fructus Momordicae is the no seed Fructus Momordicae without insect pest.
During choosing fruit, choose the Fructus Momordicae of low glycoside, moderate maturity, the arhat after microwave drying grinds
Really superfine powder can fully discharge its bioactive substance when with other component compatibilities.
Preferably, described microwave drying temperature≤75 DEG C, vacuum is-0.08～-0.098Mpa.
Preferably, described step 1) in Fructus Momordicae extract extract powder through the following steps that preparation:
A) choosing new fresh Fructus Momordicae, carry out coarse crushing after cleaning, rear employing water carries；
B) condensed water extract, forms extractum, uses and is spray-dried and makes fine powder.
Preferably, in described step a), by Fructus Momordicae coarse crushing to granularity >=20 mesh, add 2-4 times
Water, extracts 2-3 hour at 50-80 DEG C.
Preferably, described step 3) in vacuum stirring carry out in vacuum emulsifying machine, mixing time is
5-10 minute.
Compared with prior art, the invention have the benefit that
(1) abrasive material that uses in the present invention, sweeting agent, foaming agent, the toothpaste component such as aromatic are
The constituent of Fructus Momordicae, other adjuvants used also are mainly derived from biology and in food medicine
Conventional raw material, safety is good, and child can be avoided to gulp down the harm that toothpaste causes by mistake, is suitable for various people
Use.
(2) the Fructus Momordicae superfine powder of selection, Fructus Momordicae extract extract powder in the present invention, it produces work
Skill remains the health care composition of Fructus Momordicae to greatest extent, make Fructus Momordicae antiinflammatory, antibacterial, tooth protection,
The effect in cleaning oral cavity is fully played.
(3) raw material sources of Fructus Momordicae toothpaste of the present invention are wide, and production technology is simple, and production cost is low.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but this area skill
Art personnel are it will be appreciated that the following example is merely to illustrate the present invention, and are not construed as limiting the present invention
Scope.Unreceipted actual conditions person in embodiment, the condition advised according to normal condition or manufacturer
Carry out.Agents useful for same or instrument unreceipted production firm person, being can be by commercially available purchase acquisition
Conventional products.
Embodiment 1
Fructus Momordicae toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Fructus Momordicae toothpaste
The preparation of fresh Fructus Momordicae superfine powder: select that low sweet glycoside, Maturity be moderate, no seed without pest and disease damage
Fructus Momordicae, repeatedly rinses through sterilized water and dries surface water, and after microwave drying, superfine powder is broken into 140-160
Purpose micropowders saves backup at low temperatures.
Prepared by Fructus Momordicae extract extract powder: choose new fresh Fructus Momordicae, cleans and removes surface irregularities, slightly
It is broken into the granule of 20 mesh, adds water and extract 2 hours at 50 DEG C, concentrate and be spray dried to fine powder low
Save backup under temperature.
(2) the formula composition of Fructus Momordicae toothpaste: Fructus Momordicae superfine powder 18%, Fructus Momordicae extract extractum
Powder 7%, Oleum Cocois 20%, guar gum 13%, xanthan gum 22%, food stage sodium benzoate 0.4%,
Remaining is deionized water.
(3) preparation of Fructus Momordicae toothpaste: first Oleum Cocois, guar gum, xanthan gum are proportionally added into breast
In change pot, addition deionized water is sufficiently mixed and is formed uniformly original mixture, then in original mixture
It is proportionally added into Fructus Momordicae superfine powder, Fructus Momordicae extract extract powder, food stage sodium benzoate and mixes
Uniformly, in vacuum emulsifying machine, stirring makes mastic in 5 minutes, is filled into multiple tube.
Embodiment 2
Fructus Momordicae toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Fructus Momordicae toothpaste
The preparation of fresh Fructus Momordicae superfine powder: select that low sweet glycoside, Maturity be moderate, no seed without pest and disease damage
Fructus Momordicae, repeatedly rinses through sterilized water and dries surface water, and after microwave drying, superfine powder is broken into 140-160
Purpose micropowders saves backup at low temperatures.
Prepared by Fructus Momordicae extract extract powder: choose new fresh Fructus Momordicae, cleans and removes surface irregularities, slightly
It is broken into the granule of 20 mesh, adds water and extract 3 hours at 80 DEG C, concentrate and be spray dried to fine powder low
Save backup under temperature.
(2) the formula composition of Fructus Momordicae toothpaste: Fructus Momordicae superfine powder 22%, Fructus Momordicae extract extractum
Powder 5%, Oleum Cocois 25%, guar gum 16%, xanthan gum 19%, food stage sodium benzoate 0.3%,
Remaining is deionized water.
(3) preparation of Fructus Momordicae toothpaste: first Oleum Cocois, guar gum, xanthan gum are proportionally added into breast
In change pot, addition deionized water is sufficiently mixed and is formed uniformly original mixture, then in original mixture
It is proportionally added into Fructus Momordicae superfine powder, Fructus Momordicae extract extract powder, food stage sodium benzoate and mixes
Uniformly, in vacuum emulsifying machine, stirring makes mastic in 10 minutes, is filled into multiple tube.
Embodiment 3
Fructus Momordicae toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Fructus Momordicae toothpaste
The preparation of fresh Fructus Momordicae superfine powder: select that low sweet glycoside, Maturity be moderate, no seed without pest and disease damage
Fructus Momordicae, repeatedly rinses through sterilized water and dries surface water, and after microwave drying, superfine powder is broken into 140-160
Purpose micropowders saves backup at low temperatures.
Prepared by Fructus Momordicae extract extract powder: choose new fresh Fructus Momordicae, cleans and removes surface irregularities, slightly
It is broken into the granule of 20 mesh, adds water and extract 2 hours at 50 DEG C, concentrate and be spray dried to fine powder low
Save backup under temperature.
(2) the formula composition of Fructus Momordicae toothpaste: Fructus Momordicae superfine powder 15%, Fructus Momordicae extract extractum
Powder 5%, Oleum Cocois 20%, guar gum 10%, xanthan gum 15%, food stage sodium benzoate 0.1%,
Remaining is deionized water.
(3) preparation of Fructus Momordicae toothpaste: first Oleum Cocois, guar gum, xanthan gum are proportionally added into breast
In change pot, addition deionized water is sufficiently mixed and is formed uniformly original mixture, then in original mixture
It is proportionally added into Fructus Momordicae superfine powder, Fructus Momordicae extract extract powder, food stage sodium benzoate and mixes
Uniformly, in vacuum emulsifying machine, stirring makes mastic in 5 minutes, is filled into multiple tube.
Embodiment 4
Fructus Momordicae toothpaste is prepared according to following steps
(1) preparation of the main supplementary material of Fructus Momordicae toothpaste
The preparation of fresh Fructus Momordicae superfine powder: select that low sweet glycoside, Maturity be moderate, no seed without pest and disease damage
Fructus Momordicae, repeatedly rinses through sterilized water and dries surface water, and after microwave drying, superfine powder is broken into 140-160
Purpose micropowders saves backup at low temperatures.
Prepared by Fructus Momordicae extract extract powder: choose fresh fresh Fructus Momordicae and clean removing surface irregularities, slightly
It is broken into the granule of 20 mesh, adds water and extract 2 hours at 50 DEG C, concentrate and be spray dried to fine powder low
Save backup under temperature.
(2) the formula composition of Fructus Momordicae toothpaste: Fructus Momordicae superfine powder 25%, Fructus Momordicae extract extractum
Powder 10%, Oleum Cocois 30%, guar gum 20%, xanthan gum 25%, food stage sodium benzoate 0.8%,
Remaining is deionized water.
(3) preparation of Fructus Momordicae toothpaste: first Oleum Cocois, guar gum, xanthan gum are proportionally added into breast
In change pot, addition deionized water is sufficiently mixed and is formed uniformly original mixture, then in original mixture
It is proportionally added into Fructus Momordicae superfine powder, Fructus Momordicae extract extract powder, food stage sodium benzoate and mixes
Uniformly, in vacuum emulsifying machine, stirring makes mastic in 5 minutes, is filled into multiple tube.
Experience is evaluated
Choose 50 volunteers, preparation in the embodiment of the present invention 1 please be used its every day in 15 days
Toothpaste was brushed teeth 5 minutes morning, after 15 days, 50 volunteers was carried out questionnaire survey, please it be this
The scale removal of bright toothpaste, fresh breath and use are experienced (including fragrance, sugariness etc.) and are evaluated, knot
Opinion is divided into satisfied and dissatisfied, and the result being satisfied with number and satisfaction rate is as shown in the table:
| Scale removal | Fresh breath | Use impression | |
| It is satisfied with number | 42 | 48 | 43 |
| Satisfaction rate | 84% | 96% | 86% |
Fructus Momordicae toothpaste experience is evaluated
Hemostasis and anti-inflammation application case
Case 1
Zhang, 25 years old, people from hazard prevention, gingival hemorrhage Symptoms last 3 years, happen occasionally, taste
Try various Chinese herbal toothpaste to brush teeth, have no result.Act the Fructus Momordicae toothpaste using the present invention in June, 2015,
After 10 days, gingival hemorrhage symptom is improved, and adheres to that the toothpaste using the present invention is brushed teeth gingiva so far
Normal condition bleed bottom the most again.Zhang has broken away from the puzzlement of gingival hemorrhage from this.
Case 2
Slowly certain, 29 years old, Hefei ,Anhui people from city, gingival hemorrhage Symptoms last 7 years, period often occurs,
Attempt various Chinese medicine and western medicine toothpaste to brush teeth and be showed no improvement.Act the Fructus Momordicae using the present invention in August, 2015
Toothpaste, after 13 days, gingival hemorrhage symptom is improved, and adhere to use the present invention toothpaste brush teeth to
Modern gingiva normal condition bleed bottom the most again.Slowly certain has broken away from the puzzlement of gingival hemorrhage from this.
Case 3
Lee, 40 years old, people from Beijing, suffers from periodontitis 1 year, is deeply perplexed by gingival swelling and pain.From 2015
April in year acts the toothpaste using the present invention, and after one week, gingival swelling and pain phenomenon is eased, and adheres to using this
The toothpaste of invention is brushed teeth twice every day, and gingival swelling and pain phenomenon is clearly better, and progressively fully recovers.Put from this
Debentition pain puzzlement.
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that and do not carrying on the back
May be made that in the case of the spirit and scope of the present invention many other change and amendment.Therefore,
This means all these changes including belonging in the scope of the invention in the following claims and repair
Change.
Claims (10)
1. a toothpaste, it is characterised in that described toothpaste includes following components: Fructus Momordicae fine powder 15-25%,
Fructus Momordicae extract extract powder 5-10%, Oleum Cocois 20-30%, guar gum 10-20%, xanthan gum
15-25%, sodium benzoate 0.1-0.8%, surplus is deionized water.
Toothpaste the most according to claim 1, it is characterised in that the component of described toothpaste presses quality hundred
Proportion by subtraction is calculated as: Fructus Momordicae fine powder 18-22%, Fructus Momordicae extract extract powder 5-7%, Oleum Cocois 20-25%,
Guar gum 13-16%, xanthan gum 19-22%, sodium benzoate 0.3-0.4%, surplus is deionized water.
Toothpaste the most according to claim 1, it is characterised in that the granularity of described Fructus Momordicae fine powder >=
140 mesh.
Toothpaste the most according to claim 1, it is characterised in that described Fructus Momordicae extract extract powder
Granularity >=120 mesh.
5. the method preparing in claim 1-4 toothpaste described in any one, described method includes
Following steps:
1) Fructus Momordicae micropowders and Fructus Momordicae extract extract powder are prepared；
2) Oleum Cocois, guar gum, xanthan gum are proportionally added in emulsifying pot, are subsequently adding deionized water
It is sufficiently mixed and is formed uniformly original mixture；
3) to step 2) in mixture in add Fructus Momordicae micropowders, Fructus Momordicae extract extract powder
And sodium benzoate mix homogeneously, vacuum stirring makes mastic.
Method the most according to claim 5, it is characterised in that described step 1) in Fructus Momordicae
Micropowders is prepared by following steps: using the new fresh Fructus Momordicae of sterile water wash, rear microwave drying is also
Being ground into the fine powder of granularity >=120 mesh, wherein said Fructus Momordicae is the no seed Fructus Momordicae without insect pest.
Method the most according to claim 6, it is characterised in that described microwave drying temperature≤75 DEG C,
Vacuum is-0.08 to-0.098Mpa.
Method the most according to claim 5, it is characterised in that described step 1) in Fructus Momordicae
Extract extract powder through the following steps that preparation:
A) choosing new fresh Fructus Momordicae, carry out coarse crushing after cleaning, rear employing water carries；
B) condensed water extract, forms extractum, uses and is spray-dried and makes fine powder.
Method the most according to claim 8, it is characterised in that in described step a), by arhat
Really coarse crushing is to granularity >=20 mesh, adds the water of 2-4 times, extracts 2-3 hour at 50-80 DEG C.
Method the most according to claim 5, it is characterised in that described step 3) in vacuum stirring
Carrying out in vacuum emulsifying machine, mixing time is 5-10 minute.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610463770.9A CN105853318B (en) | 2016-06-23 | 2016-06-23 | A kind of toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610463770.9A CN105853318B (en) | 2016-06-23 | 2016-06-23 | A kind of toothpaste and preparation method thereof |
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| Publication Number | Publication Date |
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| CN105853318A true CN105853318A (en) | 2016-08-17 |
| CN105853318B CN105853318B (en) | 2018-07-06 |
Family
ID=56654884
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| CN201610463770.9A Active CN105853318B (en) | 2016-06-23 | 2016-06-23 | A kind of toothpaste and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108670904A (en) * | 2018-07-03 | 2018-10-19 | 海南馨原贸易有限公司 | A kind of coconut oil VC toothpaste and preparation method thereof |
| CN109464376A (en) * | 2018-12-14 | 2019-03-15 | 淮阴工学院 | It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive |
| CN109803728A (en) * | 2016-10-17 | 2019-05-24 | 高露洁-棕榄公司 | The oral care composition of appearance and form with enhancing |
| CN115282107A (en) * | 2022-08-23 | 2022-11-04 | 广西壮族自治区药用植物园 | Compound traditional Chinese medicine toothpaste and preparation |
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| CN101147751A (en) * | 2006-09-19 | 2008-03-26 | 周英 | Method for extracting biologically active component from momordica grosvenori plant |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104958225A (en) * | 2015-07-24 | 2015-10-07 | 大连民族大学 | Cherry toothpaste and preparation method thereof |
| CN105596260A (en) * | 2016-01-29 | 2016-05-25 | 海南宇星日用化工股份有限公司 | Coconut toothpaste |
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2016
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101147751A (en) * | 2006-09-19 | 2008-03-26 | 周英 | Method for extracting biologically active component from momordica grosvenori plant |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104958225A (en) * | 2015-07-24 | 2015-10-07 | 大连民族大学 | Cherry toothpaste and preparation method thereof |
| CN105596260A (en) * | 2016-01-29 | 2016-05-25 | 海南宇星日用化工股份有限公司 | Coconut toothpaste |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109803728A (en) * | 2016-10-17 | 2019-05-24 | 高露洁-棕榄公司 | The oral care composition of appearance and form with enhancing |
| CN108670904A (en) * | 2018-07-03 | 2018-10-19 | 海南馨原贸易有限公司 | A kind of coconut oil VC toothpaste and preparation method thereof |
| CN109464376A (en) * | 2018-12-14 | 2019-03-15 | 淮阴工学院 | It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive |
| CN115282107A (en) * | 2022-08-23 | 2022-11-04 | 广西壮族自治区药用植物园 | Compound traditional Chinese medicine toothpaste and preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105853318B (en) | 2018-07-06 |
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