CN109464376A - It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive - Google Patents
It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive Download PDFInfo
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- CN109464376A CN109464376A CN201811535935.4A CN201811535935A CN109464376A CN 109464376 A CN109464376 A CN 109464376A CN 201811535935 A CN201811535935 A CN 201811535935A CN 109464376 A CN109464376 A CN 109464376A
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- Prior art keywords
- lithocyte
- toothpaste
- pears
- children
- abrasive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Birds (AREA)
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- Engineering & Computer Science (AREA)
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- Tropical Medicine & Parasitology (AREA)
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- Mycology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The present invention provides a kind of using pears lithocyte as the children's toothpaste of swallowing of abrasive, is mainly configured to by following raw material: lithocyte, moisturizer, thickener, foaming agent, essence, sweetener, preservative, bacteriostatic agent, deionized water.Preparation method includes: that (A) extracts lithocyte (B) from pear flesh mentioned lithocyte added deionized water, moisturizer, foaming agent are added after ultrasound, after stirring 20min, addition thickener, essence, sweetener, preservative, bacteriostatic agent are stirred under vacuum 20min or more, form lotion.The present invention makees abrasive using natural extract pears lithocyte, and the toothpaste irritation of production is low, securely and reliably, can swallow, meet the requirement of children's toothpaste.
Description
Technical field
The invention belongs to field of toothpaste, and in particular to it is a kind of using natural green extract pears lithocyte as abrasive can
Swallow children's toothpaste and preparation method thereof.
Background technique
Lithocyte is from extracting in pear flesh, and it is harmless natural materials that main component, which is lignin,
Manufactured toothpaste can be swallowed.Lithocyte has certain friction value, can clean tooth, and will not damage enamel.Lithocyte
For ball-type crystal form, surface is smooth, it is possible to reduce the abrasion to tooth.
Child is the important period of tooth development, ensures that the oral health of child is the key that it is allowed to grow up strong and sturdy.Children
Children's enamel can should not be damaged, and its irritation is strong because adult toothpaste friction is big using adult toothpaste when brushing teeth, held
Easily cause the aversion of children, in addition, adult toothpaste fluorinated volume is obvious higher for children, exists to children's health
Hidden danger.
Many children's toothpastes now are lack of pertinence on the basis of adult toothpaste, certain constituents therein
Pediatric Oral Emergency environment may be destroyed, is threatened to Pediatric Oral Emergency health.This kind of toothpaste is only the reduction of in formula to children
The dosage of the harmful substance of health, such as fluorinated volume, but such way and unreliable, children as a specific group,
There are problems that swallowing toothpaste, if such toothpaste is used for a long time, necessarily children's torso is caused to seriously endanger.Therefore one kind is developed
Children's toothpaste can naturally be swallowed as the market demand.
Summary of the invention
There is a problem of that friction is big, irritation is strong and fluorinated volume is higher for current toothpaste, the present invention provides one kind
Using pears lithocyte as the children's toothpaste of swallowing of abrasive, making primary raw material used in toothpaste is all natural materials, floride-free
Compound, it is safe and harmless.
The present invention is achieved by the following technical solutions:
It is a kind of to swallow children's toothpaste using pears lithocyte as abrasive, it is mixed with by the raw material of following parts by weight: 2 parts
~ 10 parts of abrasives;35 parts ~ 65 parts moisturizer;0.2 part ~ 1 part thickener;1.0 parts ~ 2.5 parts surfactants;0.1 part ~ 0.5 part
Sweetener;0.1 part ~ 5 portions bacteriostatic agents;0.8 part ~ 1.5 parts essence;0.1 part ~ 0.5 portion preservative;Water surplus, total amount are 100 parts;
The abrasive is pears lithocyte;The water is deionized water.
Further improvement of the present invention scheme are as follows:
The moisturizer is the composition of sorbierite and glycerol, and the weight ratio of the glycerol and sorbierite is 1:2 ~ 3.
The thickener is the composition of cellulose gum and xanthan gum, and the weight ratio of the cellulose gum and xanthan gum is 1:
2~7。
The surfactant is one or both of laruyl alcohol sodium sulfovinate, lauroyl propylhomoserin sodium.
The sweetener is one or more of xylitol, sorbierite, saccharin sodium.
The bacteriostatic agent is one or more of dipotassium glycyrrhizinate, triclosan, Chlorhexidine.
The essence is one or both of flavoring apple essence, lemon extract, strawberry essence, grape essence, Mint Essence
More than.
The preservative is one or more of sodium benzoate, methyl hydroxybenzoate, sorbic acid.
Further improvement project of the invention are as follows:
The pears lithocyte extracts according to the following steps: weighing pear flesh, adds deionized water, blends;Concentrated hydrochloric acid is added, so that processing
Concentration of hydrochloric acid is 0.8mol/L ~ 1.2mol/L in liquid;80 DEG C of 20 ~ 40min of heat preservation, soaking time are had a rest stirring;Heat preservation terminates plus goes
Ionized water stirs, and stands, pours out upper layer suspension, rinses 5 ~ 6 times repeatedly;It filters, gained lithocyte is spread out;60~65
4 ~ 6h is dried at DEG C, is cooled to room temperature, and lithocyte is collected.
Further improvement project of the invention are as follows:
It prepares a kind of using pears lithocyte as the scheme for swallowing children's toothpaste of abrasive, comprising the following steps: lithocyte is added
Ultrasound to lithocyte is uniformly dispersed after to deionized water, addition thickener and moisturizer stir 10 ~ 30min, add thickener,
Essence, sweetener, preservative, bacteriostatic agent are stirred under vacuum, and form lotion, obtain the swallowing using pears lithocyte as abrasive
Children's toothpaste.
The invention has the benefit that
The present invention used primary raw material during making toothpaste is all natural materials, and floride-free compound is safe and harmless,
One, abrasive is pears lithocyte, and lithocyte is natural extract, is made of lignin, harmless, even if accidentally gulping down,
Can be absorbed by enteron aisle rapid digestion, crystal form be ball shape structure, using its make children's toothpaste can preferably clean tooth and
Tooth is not caused to damage.Secondly, sweetener traditional saccharin sodium is substituted with xylitol, reduce the stimulation to Pediatric Oral Emergency
Property;The nontoxic grade substance in the true border of xylitol in blood will not be converted to glucose after people's food, and can be metabolized completely;Xylitol
Also have the function of preventing decayed tooth, is natural harmless caries preventive agent.Thirdly, select the extract dipotassium glycyrrhizinate in natural Radix Glycyrrhizae to be children
The bacteriostatic agent of toothpaste can preferably inhibit bacterial growth, protection Pediatric Oral Emergency safety.
Specific implementation method
Embodiment 1 ~ 5 a kind of swallows children's toothpaste and its preparation using pears lithocyte as abrasive
Embodiment 1 ~ 5 is using pears lithocyte as the formula for swallowing children's toothpaste of abrasive such as table 1
In above-described embodiment, lithocyte is to be put into pear flesh and appropriate amount of deionized water after pulper sufficiently blends, will be to be processed
Liquid is placed in conical flask, and concentrated hydrochloric acid is added, so that the final concentration of 0.8mol/L ~ 1.2mol/L of hydrochloric acid in treatment fluid, in 80 DEG C of water
In bath heat 20 ~ 40min, intermittent stirring, after homogenate is transferred in beaker, add deionized water, with glass bar stir 1min, it is quiet
30s is set, upper layer suspension is poured out, is rinsed repeatedly according to this lithocyte 5 ~ 6 times, until cleaning, then filters, lithocyte is spread out,
It is placed in 60 ~ 65 DEG C of 4 ~ 6h of baking in baking oven, is cooled to room temperature in drier, collect lithocyte to obtain the final product.
It is prepared according to the formula in table 1 a kind of using pears lithocyte as the children's toothpaste of swallowing of abrasive, including following step
Rapid: ultrasound to lithocyte is uniformly dispersed after the deionized water of lithocyte and formula ratio is added into reactor, addition thickener with
Moisturizer stirs 10 ~ 30min, then thickener, essence, sweetener, preservative, bacteriostatic agent vacuum is added into above-mentioned reactor and stirs
20min or more is mixed, lotion is formed, obtains the children's toothpaste containing lithocyte.
Embodiment 1 ~ 5 is investigated according to GB8372 toothpaste standard, concrete outcome see the table below 2.
From upper table 2:
Embodiment 1 ~ 5 meets toothpaste GB8372 toothpaste standard basic demand, and lotion is uniform, pure white, can bring to children good
Sense organ and use feeling.
It is not fluorine-containing by above method production using pears lithocyte as the toothpaste of swallowing of abrasive, it is without any side effects,
It solves the problems, such as that children swallow toothpaste, meets the requirement of children's safety.
Claims (10)
1. a kind of swallow children's toothpaste using pears lithocyte as abrasive, which is characterized in that mixed by the raw material of following parts by weight
Conjunction is prepared: 2 parts ~ 10 parts abrasives;35 parts ~ 65 parts moisturizer;0.2 part ~ 1 part thickener;1.0 parts ~ 2.5 parts surface-actives
Agent;0.1 part ~ 0.5 part sweetener;0.1 part ~ 5 portions bacteriostatic agents;0.8 part ~ 1.5 parts essence;0.1 part ~ 0.5 portion preservative;More than water
Amount, total amount are 100 parts;
The abrasive is pears lithocyte;The water is deionized water.
2. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
It states pears lithocyte to extract according to the following steps: weighing pear flesh, add deionized water, blend;Concentrated hydrochloric acid is added, so that salt in treatment fluid
Acid concentration is 0.8mol/L ~ 1.2mol/L;80 DEG C of 20 ~ 40min of heat preservation, soaking time are had a rest stirring;Heat preservation terminates plus deionized water,
Stirring stands, pours out upper layer suspension, rinses 5 ~ 6 times repeatedly;It filters, gained lithocyte is spread out;It is dried at 60 ~ 65 DEG C
Dry 4 ~ 6h, is cooled to room temperature, and collects lithocyte.
3. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Moisturizer is stated as the composition of sorbierite and glycerol, the weight ratio of the glycerol and sorbierite is 1:2 ~ 3.
4. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Thickener is stated as the composition of cellulose gum and xanthan gum, the weight ratio of the cellulose gum and xanthan gum is 1:2 ~ 7.
5. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Stating surfactant is one or both of laruyl alcohol sodium sulfovinate, lauroyl propylhomoserin sodium.
6. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Stating sweetener is one or more of xylitol, sorbierite, saccharin sodium.
7. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Stating bacteriostatic agent is one or more of dipotassium glycyrrhizinate, triclosan, Chlorhexidine.
8. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Stating essence is one or more of flavoring apple essence, lemon extract, strawberry essence, grape essence, Mint Essence.
9. a kind of children's toothpaste is swallowed using pears lithocyte as abrasive according to claim 1, it is characterised in that: institute
Stating preservative is one or more of sodium benzoate, methyl hydroxybenzoate, sorbic acid.
10. preparing a kind of using pears lithocyte as the method for swallowing children's toothpaste of abrasive, which is characterized in that including following step
Rapid: ultrasound to lithocyte is uniformly dispersed after lithocyte is added to deionized water, and addition thickener and moisturizer stir 10 ~ 30min,
Add thickener, essence, sweetener, preservative, bacteriostatic agent, be stirred under vacuum, form lotion, obtain it is described with pears lithocyte for mill
Liniment swallows children's toothpaste.
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CN201811535935.4A CN109464376A (en) | 2018-12-14 | 2018-12-14 | It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive |
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CN201811535935.4A CN109464376A (en) | 2018-12-14 | 2018-12-14 | It is a kind of to swallow children's toothpaste and preparation method thereof using pears lithocyte as abrasive |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7175863B1 (en) * | 2005-09-15 | 2007-02-13 | Den-Mat Corporation | Method of isolating stone cells |
CN103439159A (en) * | 2013-08-22 | 2013-12-11 | 安徽农业大学 | Method for detecting distribution of lignin tissue of stone cells of pear fruit |
CN105853318A (en) * | 2016-06-23 | 2016-08-17 | 桂林亦元生现代生物技术有限公司 | Toothpaste and preparation method thereof |
-
2018
- 2018-12-14 CN CN201811535935.4A patent/CN109464376A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7175863B1 (en) * | 2005-09-15 | 2007-02-13 | Den-Mat Corporation | Method of isolating stone cells |
CN103439159A (en) * | 2013-08-22 | 2013-12-11 | 安徽农业大学 | Method for detecting distribution of lignin tissue of stone cells of pear fruit |
CN105853318A (en) * | 2016-06-23 | 2016-08-17 | 桂林亦元生现代生物技术有限公司 | Toothpaste and preparation method thereof |
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