CN102552082A - Toothpaste containing Phyllanthus emblica extracts - Google Patents
Toothpaste containing Phyllanthus emblica extracts Download PDFInfo
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- CN102552082A CN102552082A CN2011102862127A CN201110286212A CN102552082A CN 102552082 A CN102552082 A CN 102552082A CN 2011102862127 A CN2011102862127 A CN 2011102862127A CN 201110286212 A CN201110286212 A CN 201110286212A CN 102552082 A CN102552082 A CN 102552082A
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- extract
- phyllanthus emblica
- fructus phyllanthi
- toothpaste
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Abstract
The invention relates to a toothpaste containing Phyllanthus emblica extract, which contains abrasives, humectants, thickeners, foamers, sweeteners, flavors, a Phyllanthus emblica extract, adjuvants and deionized water, wherein the weight percentage of the Phyllanthus emblica extract in the formula is 0.1% to 50%; and the Phyllanthus emblica extract contains vitamin C, SOD-like antioxidant components and tannin chemicals (such as phy-13, PGG) or a combination thereof. The toothpaste containing the Phyllanthus emblica extract has the nursing effects of being capable of effectively relieving bad breath, killing bacteria, alleviating inflammation, soothing the throat, making teeth white quickly, keeping the gum healthy, can improve the antibacterial and anti-inflammatory capabilities of teeth, and protects the health of oral cavity. Besides, Phyllanthus emblica plays a role of a natural antiseptic.
Description
Technical field:
The present invention relates to a kind of toothpaste, clear and definite saying so relates to a kind of a kind of toothpaste that contains Fructus Phyllanthi extract.
Background technology:
Fructus Phyllanthi is the fruit of Euphorbiaceae phyllanthus plant Fructus Phyllanthi (Phyllanthus emblica L), another name Yunnan Fructus Canarii albi (Yunnan), Fructus Phyllanthi, Fructus Canarii albi (Sichuan), Fructus Canarii etc.Contain 17 seed amino acids in the Fructus Phyllanthi fruit (Yunnan Fructus Canarii albi), the eight amino acid that human body is necessary all contains except that tryptophan, also is rich in vitamin C in the Fructus Canarii albi of Yunnan in addition, and vitamin C also contains vitamin B1, B2 etc. simultaneously up to 3500mg/100g in its smart powder.The antioxidant content and the tannin tannin compounds (phy-13, PGG) that in the Fructus Canarii albi of Yunnan, contain similar superoxide dismutase (SOD) function are widely used in resisting pathogenic microbes, removing free radical and medicines such as antioxidation, inhibiting bacteria and diminishing inflammation, food, cosmetic field.
But because tool bitter taste in the Fructus Canarii albi of Yunnan, the mouthfeel that is used for toothpaste and can influences toothpaste is not accepted by people.
Summary of the invention:
The objective of the invention is to invent a kind of auxiliary treatment oral disease and nurse tooth simultaneously, the new type natural toothpaste of protection gingiva.
A kind of toothpaste that contains Fructus Phyllanthi extract is characterized in that it is made up of base material and Fructus Phyllanthi extract, and said Fructus Phyllanthi extract is the Fructus Phyllanthi fruit extract, and the percentage by weight of Fructus Phyllanthi extract in prescription is 0.1%-50%.
Described Fructus Phyllanthi extract is the fruit extract of Euphorbiaceae phyllanthus plant Fructus Phyllanthi (Phyllanthus emblica L).
Base material of the present invention is that what in the process of preparation toothpaste, usually to adopt is abrasivus, wetting agent, thickening agent, foaming agent, sweeting agent, flavor agent and water etc., and gets final product through the conventional method preparation of producing toothpaste.
The toothpaste that contains Fructus Phyllanthi extract of the present invention; The extract of Yunnan Fructus Canarii albi that will contain antioxidant content, the tannin tannin compounds compositions such as (phy-13, PGG) of Vc, similar superoxide dismutase (SOD) function first is added in the toothpaste; When eliminating the original bitter taste of Yunnan Fructus Canarii albi; Use its functional component that the oral cavity is nursed effectively; Reduce the extraneous damage that stimulation caused, from improving the protective capacities of tooth in essence, gingiva is played a protective role simultaneously the oral cavity.Concrete mechanism of action is following:
Vitamin C is to the effect of tooth: healthy dental bed is tightly embraced each tooth; Gingiva is a soft tissue; When lacking Vc, gingiva blood capillary collagen protein synthesis weakens, and the gingiva wall of micrangium is fragile; Be prone to cause the gingiva blood capillary to break easily to produce hemorrhage in various degree, cause oral diseases such as dental bed festers, odontoseisis, gingival atrophy; Vc has another name called ascorbic acid; It is the maximum a kind of vitamin of human body requirements amount; Have the toughness that promotes vascular collagen albumen to synthesize, increase blood vessel wall, the effect that promotes wound healing, the oral diseases such as dental bed festers, odontoseisis, gingival atrophy, oral ulcer that cause that gingival hemorrhage is caused have the effect of treatment and prevention.
The antioxidant content of similar superoxide dismutase (SOD): healthy gingiva is the firm important barrier of tooth, ties when the blood vessel of gingiva tissue enough to change, and very easily causes the generation of oral disease; Weaken cause hemorrhage in various degree such as the blood vessel wall collagen protein synthesis; The residual cytotoxicity that causes of ultra-oxygen anion free radical and peroxide radical can make lipid peroxidation in the vascular cell, destroys collagen protein; The damaging cells film causes inflammation.SOD has the peroxide radical of impelling and changes into hydrogen peroxide and oxygen, thereby the powerful effect of peroxide radical of supervening in the eliminate the inflammation process and removing ultra-oxygen anion free radical has significant antiinflammatory ability.To causing that by inflammation oral diseases such as periodontitis, gingivitis, halitosis have the effect of auxiliary treatment and prevention.
Five galloyl glucoses (PGG): contain three gallic acids in the molecular structure; According to studying the PGG that reports for work very strong antiinflammatory and bacteriostasis are arranged, so to causing that by inflammation oral diseases such as periodontitis, gingivitis, halitosis have the effect of auxiliary treatment and prevention.
The toothpaste that contains Fructus Phyllanthi extract of the present invention, can pass through verification experimental verification to the effect of drawing of oral cavity bacterium:
This experiment adopts agar diffusion method and two kinds of external bacteriostatic experiment methods mensuration of double dilution method to contain the bacteriostasis of the toothpaste of Fructus Phyllanthi extract to common oral cavity bacterium staphylococcus aureus ATCC25923, beta hemolytic streptococcus CMCC32210, staphylococcus epidermidis, ETEC ATCC25922 Streptococcus mutans ATCC25175.
Experimental result such as following table:
Agar diffusion method:
Can be obtained by last table that Fructus Phyllanthi extract all has inhibiting conclusion to common oral cavity bacterium in this Fructus Canarii albi toothpaste, wherein ETEC and Streptococcus mutans belong to slight sensitive, and all the other are medium sensitivity.
For using double dilution method, the fungistatic effect of further understanding this extract measures MIC (minimum inhibitory concentration)
Double dilution method:
The toothpaste that last table explanation contains Fructus Phyllanthi extract can effectively suppress the activity of oral cavity common bacteria, particularly staphylococcus aureus beta hemolytic streptococcus staphylococcus epidermidis is had the strong inhibition effect.
The Fructus Phyllanthi functional component vitamin C that is added among the present invention, micromolecule superoxide dismutase (SOD), tannin tannin compounds (phy-13, PGG) all are to get by extracting in the natural plants Fructus Phyllanthi fruit; Because molecular formula is less; So its absorptance is better; Meet the toothpaste additive regulation, play the effect of natural antiseptic agent simultaneously, to reduce or the use of replacement natural antiseptic agent in toothpaste.The present invention can effectively remove nursing roles such as halitosis, anti-inflammation, moistening and cleaning throat larynx refreshing, quick tooth-whitening, firm gingiva; Improved the anti-inflammation ability of tooth; Oral health is played a protective role, and Fructus Phyllanthi also plays the effect of natural antiseptic agent simultaneously.
The specific embodiment
Below in conjunction with embodiment the present invention is done further explanation, but be not limited to embodiment.
Embodiment 1.
A kind of care toothpaste that contains the Yunnan Fructus Canrii Albi extract, its constituent and percentage by weight are following:
Abrasivus hydration Silicon stone 40%
Wetting agent glycerol 8% sorbitol 15%
Thickening agent cellulose gum 0.3% xanthan gum 0.6%
Foaming agent sodium lauryl sulfate 1%
Sweeting agent xylitol 0.5% saccharin sodium 0.3%
Flavor agent essence 1.2%
Fructus Phyllanthi extract 0.1%
Deionized water 32.6%
Additive sodium benzoate 0.1% tetrasodium pyrophosphate 0.3%
Method for preparing: in load weighted deionized water, the pure and mild saccharin sodium of wooden carbon, sodium benzoate, Fructus Phyllanthi extract, partial glycerol and sorbitol input system cream still, begin to stir.In pre-dispersed still, cellulose gum, xanthan gum and remaining glycerol and sorbitol are processed uniform dispersion, join again in the system cream still, stir; Again with in hydration Silicon stone, the sodium lauryl sulfate input system cream still; Open vacuum pump, scraper and colloid mill, with the remaining mixing of materials input system cream still of material, charging finishes behind the operand minute; Wait to make in the cream still vacuum pressure and reach back homogenizing 15 minutes; Close vacuum pump, scraper and colloid mill afterwards successively, pump into mastic after the sampling detection is qualified and store in the pot, change packaging process over to.
Case study on implementation 2.
A kind of care toothpaste that contains the Yunnan Fructus Canrii Albi extract, its constituent and percentage by weight are following:
Abrasivus hydration Silicon stone 40%
Wetting agent glycerol 8% sorbitol 15%
Thickening agent cellulose gum 0.3% xanthan gum 0.6%
Foaming agent sodium lauryl sulfate 1%
Sweeting agent xylitol 0.5% saccharin sodium 0.5%
Flavor agent essence 1.2%
Fructus Phyllanthi extract 10%
Deionized water 22.5%
Additive sodium benzoate 0.1% tetrasodium pyrophosphate 0.3%
Method for preparing: in load weighted deionized water, the pure and mild saccharin sodium of wooden carbon, sodium benzoate, Fructus Phyllanthi extract, partial glycerol and sorbitol input system cream still, begin to stir.In pre-dispersed still, cellulose gum, xanthan gum and remaining glycerol and sorbitol are processed uniform dispersion, join again in the system cream still, stir; Again with in hydration Silicon stone, the sodium lauryl sulfate input system cream still; Open vacuum pump, scraper and colloid mill, with the remaining mixing of materials input system cream still of material, charging finishes behind the operand minute; Wait to make in the cream still vacuum pressure and reach back homogenizing 15 minutes; Close vacuum pump, scraper and colloid mill afterwards successively, pump into mastic after the sampling detection is qualified and store in the pot, change packaging process over to.
Case study on implementation 3.
A kind of care toothpaste that contains the Yunnan Fructus Canrii Albi extract, its constituent and percentage by weight are following:
Abrasivus hydration Silicon stone 36%
Wetting agent glycerol 8% sorbitol 15%
Thickening agent cellulose gum 0.3% xanthan gum 0.6%
Foaming agent sodium lauryl sulfate 1%
Sweeting agent xylitol 0.5% saccharin sodium 0.5%
Flavor agent essence 1.2%
Fructus Phyllanthi extract 25%
Deionized water 11.5%
Additive sodium benzoate 0.1% tetrasodium pyrophosphate 0.3%
Method for preparing: in load weighted deionized water, the pure and mild saccharin sodium of wooden carbon, sodium benzoate, Fructus Phyllanthi extract, partial glycerol and sorbitol input system cream still, begin to stir.In pre-dispersed still, cellulose gum, xanthan gum and remaining glycerol and sorbitol are processed uniform dispersion, join again in the system cream still, stir; Again with in hydration Silicon stone, the sodium lauryl sulfate input system cream still; Open vacuum pump, scraper and colloid mill, with the remaining mixing of materials input system cream still of material, charging finishes behind the operand minute; Wait to make in the cream still vacuum pressure and reach back homogenizing 15 minutes; Close vacuum pump, scraper and colloid mill afterwards successively, pump into mastic after the sampling detection is qualified and store in the pot, change packaging process over to.
Case study on implementation 4.
A kind of care toothpaste that contains the Yunnan Fructus Canrii Albi extract, its constituent and percentage by weight are following:
Abrasivus hydration Silicon stone 25%
Wetting agent glycerol 7% sorbitol 12%
Thickening agent cellulose gum 0.3% xanthan gum 0.7%
Foaming agent sodium lauryl sulfate 1%
Sweeting agent xylitol 0.5% saccharin sodium 0.5%
Flavor agent essence 1.2%
Fructus Phyllanthi extract 40%
Deionized water 11.5%
Additive sodium benzoate 0.05% tetrasodium pyrophosphate 0.25%
Method for preparing: in load weighted deionized water, the pure and mild saccharin sodium of wooden carbon, sodium benzoate, Fructus Phyllanthi extract, partial glycerol and sorbitol input system cream still, begin to stir.In pre-dispersed still, cellulose gum, xanthan gum and remaining glycerol and sorbitol are processed uniform dispersion, join again in the system cream still, stir; Again with in hydration Silicon stone, the sodium lauryl sulfate input system cream still; Open vacuum pump, scraper and colloid mill, with the remaining mixing of materials input system cream still of material, charging finishes behind the operand minute; Wait to make in the cream still vacuum pressure and reach back homogenizing 15 minutes; Close vacuum pump, scraper and colloid mill afterwards successively, pump into mastic after the sampling detection is qualified and store in the pot, change packaging process over to.
Embodiment five.
A kind of care toothpaste that contains the Yunnan Fructus Canrii Albi extract, its constituent and percentage by weight are following:
Abrasivus hydration Silicon stone 15%
Wetting agent glycerol 7% sorbitol 11%
Thickening agent cellulose gum 0.3% xanthan gum 0.7%
Foaming agent sodium lauryl sulfate 1%
Sweeting agent xylitol 0.5% saccharin sodium 0.5%
Flavor agent essence 1.2%
Fructus Phyllanthi extract 50%
Deionized water 12.5%
Additive sodium benzoate 0.05% tetrasodium pyrophosphate 0.25%
Method for preparing: in load weighted deionized water, the pure and mild saccharin sodium of wooden carbon, sodium benzoate, Fructus Phyllanthi extract, partial glycerol and sorbitol input system cream still, begin to stir.In pre-dispersed still, cellulose gum, xanthan gum and remaining glycerol and sorbitol are processed uniform dispersion, join again in the system cream still, stir; Again with in hydration Silicon stone, the sodium lauryl sulfate input system cream still; Open vacuum pump, scraper and colloid mill, with the remaining mixing of materials input system cream still of material, charging finishes behind the operand minute; Wait to make in the cream still vacuum pressure and reach back homogenizing 15 minutes; Close vacuum pump, scraper and colloid mill afterwards successively, pump into mastic after the sampling detection is qualified and store in the pot, change packaging process over to.
Claims (2)
1. a toothpaste that contains Fructus Phyllanthi extract is characterized in that, it is made up of base material and Fructus Phyllanthi extract, and said Fructus Phyllanthi extract is the Fructus Phyllanthi fruit extract, and the percentage by weight of Fructus Phyllanthi extract in prescription is 0.1%-50%.
2. a kind of toothpaste that contains Fructus Phyllanthi extract according to claim 1 is characterized in that, described Fructus Phyllanthi extract is the fruit extract of Euphorbiaceae phyllanthus plant Fructus Phyllanthi (Phyllanthus emblica L).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2011102862127A CN102552082A (en) | 2011-09-24 | 2011-09-24 | Toothpaste containing Phyllanthus emblica extracts |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011102862127A CN102552082A (en) | 2011-09-24 | 2011-09-24 | Toothpaste containing Phyllanthus emblica extracts |
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| CN102552082A true CN102552082A (en) | 2012-07-11 |
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| CN2011102862127A Pending CN102552082A (en) | 2011-09-24 | 2011-09-24 | Toothpaste containing Phyllanthus emblica extracts |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705725A (en) * | 2013-12-30 | 2014-04-09 | 广西梧州制药（集团）股份有限公司 | Throat-clearing anti-inflammatory traditional Chinese medicine composite and preparation method thereof |
| CN106924162A (en) * | 2017-03-27 | 2017-07-07 | 云南西草资源开发有限公司 | A kind of application of plant additive, bacteriostatic agent, oral care product and plant additive in oral care product is prepared |
| CN108904541A (en) * | 2018-07-12 | 2018-11-30 | 石河子大学 | Inhibit the production method and purposes of periodontal disease pathogenic bacteria active component in galla turcica |
| CN108969456A (en) * | 2018-09-06 | 2018-12-11 | 广西医科大学 | Anti-inflammatory toothpaste of whitening and preparation method thereof |
| CN114224774A (en) * | 2022-01-27 | 2022-03-25 | 深圳中科欣扬生物科技有限公司 | Oral care formula with anti-inflammatory, antioxidant and repairing effects and preparation method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101502482A (en) * | 2009-03-27 | 2009-08-12 | 玉溪健坤生物药业有限公司 | Toothpaste containing coenzyme Q10 and preparation method thereof |
-
2011
- 2011-09-24 CN CN2011102862127A patent/CN102552082A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101502482A (en) * | 2009-03-27 | 2009-08-12 | 玉溪健坤生物药业有限公司 | Toothpaste containing coenzyme Q10 and preparation method thereof |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705725A (en) * | 2013-12-30 | 2014-04-09 | 广西梧州制药（集团）股份有限公司 | Throat-clearing anti-inflammatory traditional Chinese medicine composite and preparation method thereof |
| CN106924162A (en) * | 2017-03-27 | 2017-07-07 | 云南西草资源开发有限公司 | A kind of application of plant additive, bacteriostatic agent, oral care product and plant additive in oral care product is prepared |
| CN106924162B (en) * | 2017-03-27 | 2019-12-06 | 云南西草资源开发有限公司 | Plant additive, bacteriostatic agent, oral care product and application of plant additive in preparation of oral care product |
| CN108904541A (en) * | 2018-07-12 | 2018-11-30 | 石河子大学 | Inhibit the production method and purposes of periodontal disease pathogenic bacteria active component in galla turcica |
| CN108969456A (en) * | 2018-09-06 | 2018-12-11 | 广西医科大学 | Anti-inflammatory toothpaste of whitening and preparation method thereof |
| CN114224774A (en) * | 2022-01-27 | 2022-03-25 | 深圳中科欣扬生物科技有限公司 | Oral care formula with anti-inflammatory, antioxidant and repairing effects and preparation method |
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Application publication date: 20120711 |