KR20170053073A

KR20170053073A - Anti-ache toothpaste containing extracts from lentinula edodes

Info

Publication number: KR20170053073A
Application number: KR1020150155373A
Authority: KR
Inventors: 조원진
Original assignee: 조원진
Priority date: 2015-11-05
Filing date: 2015-11-05
Publication date: 2017-05-15

Abstract

The toothpaste for preventing syringe containing the extract of Tetranychophila marigata of the present invention is a sensory agent comprising potassium nitrate as an additive; A sweetening agent containing at least one of xylitol, steviol glycoside and erythritol as an additive; A binder comprising sodium carboxymethylcellulose as an additive; A bone strengthening agent comprising hydroxyapatite as an additive; Amorphous sorbitol solution (70%), wetting agent containing at least one of glycerin as an additive; An abrasive containing dental type silica as an additive; A solvent containing purified water as an additive; A flavoring agent containing at least one of grapefruit seed extract, sodium cocoyl glutamate, el (L) -menthol, colemide EM-998, and mint NF-0376 as additives; An anti-aging agent containing sodium fluoride (1000 PPM) as an additive; And an antioxidant comprising at least one of ascorbic acid, tocopherol, rosemary extract, and white algae extract as an additive.

Description

ANTI-ACHE TOOTHPASTE CONTAINING EXTRACTS FROM LENTINULA EDODES "

More particularly, the present invention relates to a toothpaste for prevention of gum disease by enhancing immunity such as skin disease improvement and anti-cancer, alleviating symptoms of acinic acid, The present invention also relates to a toothpaste for preventing syringe which contains an extract of White Hwanggae.

The mouth of the human body is the entrance of the digestive tract, which is digested by the action of the lower jaw, the action of the teeth, chewing the food by cooperating with the ball, tongue and lips, and mixing the needles with food to decompose the starch into starch digestive enzymes The food is delivered to the esophagus, the mouth makes sound, and the taste acts to taste the food.

In the mouth of the human body, the tongue which helps the taste of the food and the organs of the food, and the tooth which breaks and breaks the food by the chewing and cutting is surrounded by the upper and lower periodontal bone (gum bone). However, due to the remaining of the ingested material, In addition to oral bacteria, many bacteria are known to cause inflammation. One of these bacteria is Helicobacter pylori, which is known as a cause of gastritis, gastric ulcer and gastric cancer. It has been reported in the academia that it is resident in the stomach and oral cavity by vomiting and vomiting.

In addition, diseases that can occur in teeth include tooth decay and periodontal disease, which are caused by oral microorganisms such as Streptococcus mutans, Lactobacillus, E. coli, and the like , The microorganisms decompose sugars to form insoluble glucan. These are attached to the surface of teeth together with various microbes to form tartar. The microorganisms attached to these calculi decompose sugar to dissolve the etamer layer on the surface of the teeth The tooth cavity is generated, and the discomfort is dissolved by the body of the bacteria, and periodontal disease occurs.

As such, the mouth (oral cavity and teeth, periodontal bone) is a state of cleansing only the inhibition of the activity of microorganisms in the oral cavity. In order to maintain the cleanliness of the oral cavity for a long time, microorganisms There is a desperate need to develop dentifrice compositions that control activity and inhibit bacterial growth.

In the development of dentifrice compositions, dentifrices have been demanded which can alleviate the symptoms of acne, improve the skin diseases, increase immunity such as anti-cancer, and inhibit the growth of oral bacteria, the occurrence of gum disease and the formation of calculus, There has been a problem in that a toothpaste satisfying the above is not developed.

Korean Patent Publication No. 10-2010-0080295

The technical problem to be solved by the present invention is to provide a toothpaste for prevention of gum disease by preventing the gum disease by enhancing immunity such as skin disease improvement and anti-cancer, alleviating the symptoms of acinic acid, .

In order to accomplish the above object, the present invention provides a toothpaste for preventing syringe, which comprises a white flour extract, comprising: a sensory agent comprising potassium nitrate as an additive; A sweetening agent containing at least one of xylitol, steviol glycoside and erythritol as an additive; A binder comprising sodium carboxymethylcellulose as an additive; A bone strengthening agent comprising hydroxyapatite as an additive; Amorphous sorbitol solution (70%), wetting agent containing at least one of glycerin as an additive; An abrasive containing dental type silica as an additive; A solvent containing purified water as an additive; A flavoring agent containing at least one of grapefruit seed extract, sodium cocoyl glutamate, el (L) -menthol, colemide EM-998, and mint NF-0376 as additives; An anti-aging agent containing sodium fluoride (1000 PPM) as an additive; And an antioxidant comprising at least one of ascorbic acid, tocopherol, rosemary extract and white algae extract as an additive.

The present invention has the technical effect of improving the skin diseases, increasing the immunity such as anti-cancer, alleviating the symptoms of acinar disease, and maintaining the teeth firmly to prevent gum disease.

Hereinafter, specific embodiments of the present invention will be described in detail.

The toothpastes for prevention of sickness include the sensory agent, the sweetener, the binder, the bone strengthening agent, the wetting agent, the abrasive agent, the solvent, the flavoring agent, the anti-aging agent and the antioxidant which are commonly used as the dentifrice composition according to the present invention.

Each of the dentifrice compositions used in the present invention, purpose of blending, amounts used and the like will be described in detail below.

In the present invention, potassium nitrate is used as a sensory agent, but not limited thereto, tricalcium phosphate, strontium chloride and the like can be used, and the sensory agent The amount to be used is 3.1 to 8.3% by weight, preferably 5.0% by weight, based on the total weight of the dentifrice composition.

In this case, dental hypersensitivity (sylvian) is a condition in which the tooth part (dentin) exposed because the enamel or periodontal tissue, which is the outermost layer of teeth, is lost pathologically or physiologically is exposed to external stimuli such as mechanical stimulation, temperature change, osmotic pressure, Symptoms indicate syringe or pain. When the concentration of potassium ion on the surface of the dentin increases, it blocks the nerve conduction function of the dentinal tubules existing in the dentin, and it can relieve the symptoms of acinine.

In the present invention, xylitol, steviol glycosides and erythritol were used, but the present invention is not limited to these, and it is possible to use salicylate, sucralose, sucrose, sorbitol, The amount of the sweetener to be used may be in the range of 0.001 to 20% by weight based on the total weight of the dentifrice composition. The amount of the sweetener may be in the range of 0.001 to 20% by weight based on the total weight of the dentifrice composition .

The binder is added to increase the strength of the product when the sample is sintered or molded. Carboxymethylcellulose sodium is used in the present invention. However, the binder is not limited thereto, and cellulose gum, xanthan gum, sodium alginate, polyacrylate , Carrageenan, natural gums and the like. The amount of the binder to be used is 0.1 to 5% by weight, preferably 0.5 to 3% by weight, based on the total weight of the dentifrice composition.

The bone strengthening agent is used as a coating agent for promoting ingrowth of bone. In the case of the present invention, hydroxyapatite is used. The amount of bone strengthening agent is used in the range of 0.001 to 20 wt% If the content is less than 0.001% by weight, the effect of re-crystallization is deteriorated. If the content is more than 20% by weight, the component may lose its inherent properties.

In this case, remineralization plays a role in regenerating and restoring hydroxyapatite, which is a main component of teeth, and the main component of hydroxyapatite is composed of bivalent calcium cation and phosphate anion.

Therefore, if calcium ion or phosphate ion is supplied at the same time, or calcium ion or phosphate anion is contained in the oral cavity to move the hydroxyapatite to the side where the chemical equilibrium is generated, it can be a remineralizing agent.

On the other hand, the substance that provides calcium and phosphorus is selected from the group consisting of hydroxyapatite, dicalcium phosphate, calcium chloride, casein phosphopeptide, calcium glycerophosphate, sodium phosphate monobasic, sodium phosphate dibasic, , Potassium secondary phosphate, potassium tertiary phosphate, and the like.

The wetting agent is an essential ingredient for making ointment formulations. It prevents the toothpaste from drying and solidifying when the toothpaste is exposed to the air, and provides a luster on the surface of toothpaste, and also provides a sweetening effect when brushing according to the kind. (70%) and glycerin were used as the wetting agent, but not limited thereto, hyaluronic acid, sorbitol, ethylene glycol, propylene glycol, polypropylene glycol, polyethylene glycol 1500 and the like can be used. By weight, or 20 to 60% by weight, preferably 20 to 50% by weight, of a mixture of two or more thereof.

In the present invention, the dental type silica is used as the abrasive in the present invention, but the present invention is not limited to this, and the abrasive may include silicon dioxide, calcium monohydrogenphosphate, precipitated silica, fumed silica , A colloidal silica, a zeolite, calcium carbonate, hydrated alumina, kaolin, cellulose, and mixtures thereof. The abrasive may be used in an amount of 0.1 to 30% by weight based on the total weight of the dentifrice composition, Preferably 1 to 20% by weight.

In this case, if the content of the abrasive is less than 0.1% by weight, the toothpaste will not exhibit a cleansing power because it does not exhibit a polishing degree, and if it exceeds 30% by weight, sufficient washing power can not be obtained compared with the content, have.

In the present invention, purified water is used. However, it is not limited to this and organic solvents such as ethanol may be used. The amount of the solvent to be used is 1 to 90% by weight based on the total weight of the dentifrice composition, Preferably in an amount of 10 to 60% by weight.

The flavoring agent is a constituent material of the perfume, such as aromatic chemicals, essential oils, natural extracts, distillates, isolates, aromas, resinous resins, etc. In the case of the present invention, grapefruit seed extract, sodium cocoyl glutamate, L-menthol, Coulter EM-998 and Mint NF-0376 were used. The amount of the flavoring agent to be used may be 0.001 to 10% by weight based on the total weight of the dentifrice composition.

The anticariogenic agent suppresses the growth of tooth decay bacteria or inhibits the formation of calculus. Fluoride ion is used as a dentifrice composition. In the present invention, sodium fluoride (1000 PPM) is used as the anti-wrinkle agent. But not limited to, a soluble alkali metal salt including potassium fluoride, ammonium fluorosilicate, sodium fluorosilicate, sodium fluorophosphate, and tin fluoride such as 1-tin fluoride, and the amount of the anti- May be used in the range of 0.1 to 0.3% by weight.

In this case, the fluorine (F) component contained in the dentifrice composition has the effect of relieving the symptoms of acinine, which is supplied in the form of a solution or a gel, and induces remineralization of teeth through local application, Thereby promoting calcification of the surface.

The antioxidant acts on the free radicals and peroxides generated in the oxidation process of food components by oxygen in the air to stop the chain reaction of oxidation and prevent the progress of oxidation and to prevent the degradation of food, The present invention uses ascorbic acid, tocopherol, rosemary extract and Brassica oleracea extract as an antioxidant in an amount of 0.1 to 1.0% by weight based on the total weight of the dentifrice composition .

Hereinafter, the efficacy, production method and extraction method of the present invention as a feature of the present invention will be described in detail.

The dental composition of the present invention contains a large amount of proteins, various amino acids, vitamin B, vitamin D and minerals, and helps to prevent skin aging through antioxidative action to remove active oxygen promoting skin aging Atopic dermatitis, acne and inflammation, eczema and skin diseases such as redness and anti-cancer, antitumor polysaccharide Lentinen, which contains the substance to increase immunity, cancer cells to prevent the proliferation of high blood pressure and anti-cancer effect It is also known that vitamin B1, B2 and vitamin D ergosterrine are contained in large amounts to strengthen the bones and promote absorption of calcium and phosphorus.

1. Mushroom production method

(1) After oak crushing,

(2) Inoculation of seed after seeding (work around September)

(3) browning

It takes about 120 days to mature the seed to spread evenly on the oak medium.

(4) Standing

It takes 30 days to win after 24 hours of inundation, 3 days after 35 days, and 3 days after inundation.

(5) After production, it is dried in natural sunlight for 3 days, dried in a dryer and stored

2. Mushroom Extract Method

(1) Dust of dry baggage is cleaned

Although the flora can be used both as a living thing and as a dried one, the water content can be adjusted to less than 10%, for example, through drying because the dry bleaching flour is more effective than the living thing.

(2) The dried white flour is put into a heavy steam pressure tank, and 12 kg of white flour is added to 150 L of water, followed by heating. In this case, heating is carried out at 0 to 80 ° C. for 1 hour, at 80 to 100 ° C. for 1 hour, After heating for 1 hour, the main component of the flour is hydrothermally extracted.

(3) After extracting the hot water, the extract is separated and kept at 80 ℃ or higher. It is stored at 18 ℃. In this case, care should be taken that the longest extract does not exceed 3 months.

(4) Extracted extracts of Baekhwago were prepared on the same day when the toothpaste was prepared.

Table 1 below shows examples of the compositions, the purpose of blending, and the contents of the toothpastes for preventing syringe containing the extract of T. ssuki according to the present invention.

With reference to Table 1, the main features of the anti-syringe-containing toothpaste containing the extract of White Hwacheon according to the present invention will be summarized.

First, the toothpaste for preventing syringe containing the extract of Paeonia japonica according to the present invention is obtained by using 1.0% by weight based on the total weight of the dentifrice composition, (Through comparison of Comparative Examples 1 and 2 and Example 1), it exhibits an excellent effect of improving skin diseases and improving immunity such as anti-cancer.

Second, the toothpaste for preventing syringe according to the present invention containing 5.0 wt% of potassium nitrate as a sensory agent based on the total weight of the dentifrice composition (through comparison of Comparative Examples 1 and 2 and Example 1) (1000PPM) as the anti-wrinkle agent was used in an amount of 0.220% by weight based on the total weight of the dentifrice composition (Comparative Example 1, Comparative Example 1, and Comparative Example 2) 2 and Example 1), it induces remineralization of the teeth to promote the calcification of the tooth surface, thereby exhibiting an excellent effect of reducing the feeling of sharpness.

Third, the toothpaste for preventing syringe according to the present invention containing 5.0% by weight of hydroxyapatite as a bone strengthening agent based on the total weight of the dentifrice composition (through comparison of Comparative Examples 1 and 2 and Example 1) , And it has a technical feature that it produces a durable tooth and shows an excellent effect on gum disease.

While the present invention has been described in connection with what is presently considered to be the most practical and preferred embodiment, it is to be understood that the invention is not limited to the disclosed embodiments. It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit of the invention.

Claims

A sensory agent comprising potassium nitrate as an additive;
A sweetening agent containing at least one of xylitol, steviol glycoside and erythritol as an additive;
A binder comprising sodium carboxymethylcellulose as an additive;
A bone strengthening agent comprising hydroxyapatite as an additive;
Amorphous sorbitol solution (70%), wetting agent containing at least one of glycerin as an additive;
An abrasive containing dental type silica as an additive;
A solvent containing purified water as an additive;
A flavoring agent containing at least one of grapefruit seed extract, sodium cocoyl glutamate, el (L) -menthol, colemide EM-998, and mint NF-0376 as additives;
An anti-aging agent containing sodium fluoride (1000 PPM) as an additive; And
Ascorbic acid, tocopherol, rosemary extract, and white mugwort extract, and an antioxidant containing at least one of these as an additive.

[3] The method of claim 1,
It is obtained by adding 12kg of dried white rice flour to 150L water and then heating it at 0 ~ 80 ℃ for 1 hour, followed by secondary heating at 80 ~ 100 ℃ for 1 hour and third heating at 100 ~ 114 ℃ for 1 hour. Toothpaste containing anti-inflammatory herbal extracts.

[3] The composition of claim 2,
The toothpaste according to claim 1, wherein the toothpaste composition comprises 0.1 to 1.0 part by weight based on the total weight of the dentifrice composition.