CN105832987A - 一种治疗突发性耳聋的中药组合物 - Google Patents

一种治疗突发性耳聋的中药组合物 Download PDF

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CN105832987A
CN105832987A CN201610349199.8A CN201610349199A CN105832987A CN 105832987 A CN105832987 A CN 105832987A CN 201610349199 A CN201610349199 A CN 201610349199A CN 105832987 A CN105832987 A CN 105832987A
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柳晖
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Abstract

本发明公开了一种治疗突发性耳聋的中药组合物,其中药原料及重量份配比为:石菖蒲10‑30份,川芎10‑20份,酸枣仁10‑20份,鹿茸5‑15份,骨碎补10‑20份,葛根10‑20份,龙眼肉10‑20份,陈皮5‑15份,枸杞10‑20份,山茱萸10‑20份,红花5‑15份,石蕊10‑20份,磁石10‑20份,磨盘草10‑20份,槐花5‑15份,女贞子10‑20份,石龙刍10‑20份,蛇蜕5‑15份,龙齿10‑20份,菟丝子10‑20份,知母5‑15份,乌金草10‑20份,甘草5‑15份。本发明中药组合物具有清热解毒、活血祛淤、通络开窍、补益肝肾的功效,其治疗突发性耳聋疗效显著,作用可靠。

Description

一种治疗突发性耳聋的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗突发性耳聋的中药组合物。
背景技术
突发性耳聋是突然的、原因不明的感音神经性听力损失。多发生于单侧耳,亦偶见双耳同时发病或先后发病。常见病因有病毒感染、血管疾病、内淋巴水肿、迷路膜破裂等。临床上一般表现为单侧听力下降,可伴有耳鸣、耳堵塞感、眩晕、呕吐等。目前,临床上治疗突发性耳聋通常采用糖皮质激素、溶栓和抗凝药物治疗,虽然具有一定疗效,但长期服用,易产生依赖性,并且药物的副作用会对人体的免疫系统造成很大的伤害。
中医认为,突发性耳聋是因突发性耳聋多为气滞血淤,耳部经络被淤血所阻塞,清阳之气不能上达于耳窍,使得耳部的正常生理功能减退,从而发生了耳鸣、耳聋等表现。
根据中医理论,针对突发性耳聋的发病机理,以活血祛淤,通络开窍为治则,进行辩证配伍组方,以达到标本兼治的目的。
发明内容
为了克服现有技术中采用糖皮质激素、溶栓和抗凝药物治疗突发性耳聋存在副作用大的不足,本发明提供一种配制方便、疗效显著、作用可靠、无副作用的治疗突发性耳聋的中药组合物。
本发明解决其技术问题所采用的技术方案是:一种治疗突发性耳聋的中药组合物,其特征在于:其中药原料及重量份配比为:石菖蒲10-30份,川芎10-20份,酸枣仁10-20份,鹿茸5-15份,骨碎补10-20份,葛根10-20份,龙眼肉10-20份,陈皮5-15份,枸杞10-20份,山茱萸10-20份,红花5-15份,石蕊10-20份,磁石10-20份,磨盘草10-20份,槐花5-15份,女贞子10-20份,石龙刍10-20份,蛇蜕5-15份,龙齿10-20份,菟丝子10-20份,知母5-15份,乌金草10-20份,甘草5-15份。
本发明的优选技术方案是:一种治疗突发性耳聋的中药组合物,其特征在于:其中药原料及重量份配比为:石菖蒲20份,川芎15份,酸枣仁15份,鹿茸10份,骨碎补15份,葛根15份,龙眼肉15份,陈皮10份,枸杞15份,山茱萸15份,红花10份,石蕊15份,磁石15份,磨盘草15份,槐花10份,女贞子15份,石龙刍15份,蛇蜕10份,龙齿15份,菟丝子15份,知母10份,乌金草15份,甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:石菖蒲具有化痰开窍、化湿行气、祛风利痹、消肿止痛的功效;川芎具有活血祛瘀、行气开郁、祛风止痛的功效;酸枣仁具有养肝敛汗、宁心安神的功效;鹿茸具有壮肾阳、补气血、益精髓、强筋骨的功效;骨碎补具有补肾强骨、续伤止痛的功效;葛根具有发表解肌、升阳透疹、解热生津的功效;龙眼肉具有补益心脾、养血安神的功效;陈皮具有理气健脾、调中利水、燥湿化痰的功效;枸杞具有养肝明目、扶正固本、生精补髓、滋阴补肾、益气安神的功效;山茱萸具有补益肝肾、涩精固脱的功效;红花具有活血通经、散瘀止痛的功效;石蕊具有清热、润燥、凉肝、化痰、利湿的功效;磁石具有平肝潜阳、安神镇惊、聪耳明目、纳气平喘的功效;磨盘草具有疏风清热、化痰止咳、消肿解毒的功效;槐花具有凉血止血、清肝泻火的功效;女贞子具有滋补肝肾、益阴养血的功效;石龙刍具有利水通淋、泄热、安神、凉血止血的功效;蛇蜕具有祛风、定惊、退翳、解毒的功效;龙齿具有镇惊安神、清热除烦的功效;菟丝子具有补肾益精、养肝健脾的功效;知母具有清热泻火、生津润燥的功效;乌金草具有平肝阳、养心安神、养血调经的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏清热解毒、活血祛淤、通络开窍、补益肝肾之功效,对突发性耳聋达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率91%,治愈率达63.8%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例 1
一种治疗突发性耳聋的中药组合物,其中药原料及重量配比为:石菖蒲20g,川芎15g,酸枣仁15g,鹿茸10g,骨碎补15g,葛根15g,龙眼肉15g,陈皮10g,枸杞15g,山茱萸15g,红花10g,石蕊15g,磁石15g,磨盘草15g,槐花10g,女贞子15g,石龙刍15g,蛇蜕10g,龙齿15g,菟丝子15g,知母10g,乌金草15g,甘草10g。
实施例 2
一种治疗突发性耳聋的中药组合物,其中药原料及重量配比为:石菖蒲30g,川芎10g,酸枣仁20g,鹿茸5g,骨碎补20g,葛根10g,龙眼肉20g,陈皮5g,枸杞20g,山茱萸10g,红花15g,石蕊10g,磁石20g,磨盘草10g,槐花15g,女贞子10g,石龙刍20g,蛇蜕5g,龙齿20g,菟丝子10g,知母15g,乌金草10g,甘草15g。
实施例 3
一种治疗突发性耳聋的中药组合物,其中药原料及重量配比为:石菖蒲10g,川芎20g,酸枣仁10g,鹿茸15g,骨碎补10g,葛根20g,龙眼肉10g,陈皮15g,枸杞10g,山茱萸20g,红花5g,石蕊20g,磁石10g,磨盘草20g,槐花5g,女贞子20g,石龙刍10g,蛇蜕15g,龙齿10g,菟丝子20g,知母5g,乌金草20g,甘草5g。
实施例 4
一种治疗突发性耳聋的中药组合物,其中药原料及重量配比为:石菖蒲23份,川芎12g,酸枣仁18g,鹿茸7g,骨碎补18g,葛根12g,龙眼肉18g,陈皮7g,枸杞18g,山茱萸12g,红花13g,石蕊12g,磁石18g,磨盘草12g,槐花13g,女贞子12g,石龙刍18g,蛇蜕7g,龙齿18g,菟丝子12g,知母13g,乌金草12g,甘草13g。
实施例 5
一种治疗突发性耳聋的中药组合物,其中药原料及重量配比为:石菖蒲17份,川芎18g,酸枣仁12g,鹿茸13g,骨碎补12g,葛根18g,龙眼肉12g,陈皮13g,枸杞12g,山茱萸18g,红花7g,石蕊18g,磁石12g,磨盘草18g,槐花7g,女贞子18g,石龙刍12g,蛇蜕13g,龙齿12g,菟丝子18g,知母7g,乌金草18g,甘草7g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行第一次煎煮,未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二次煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。
本发明以实施例1所给出的一种治疗突发性耳聋的中药组合物,做临床疗效总结如下:
一、一般性资料:本发明中药组合物应用于临床观察病例47例,其中,男25例,女22例,年龄25~50岁。
二、诊断标准:
1、听力突然下降,1~2天内听力下降达到高峰,多为单耳发病;或伴耳鸣、眩晕;
2、常有恼怒、劳累、感寒等诱因;
3、耳部检查:鼓膜多无明显变化,或有鼓膜混浊;
4、听力检查呈感音神经性聋;
5、应与耳眩晕、耳胀相鉴别。
三、用法用量:临床应用时,一天一剂,水煎两遍取汁约400ml,分早、晚两次温热服用,六天为一疗程。
四、疗效标准:
1、治愈:听力恢复正常;
2、好转:听力提高10分贝以上,耳中不适感减轻;
3、未愈:听力提高不足10分贝。
五、治疗效果:该临床观察病例中,服药5-10个疗程,治愈30例,好转13例,未愈4例。治疗期间未发生毒副作用。
六、典型病例:
病例1:钱某,男,37岁。就诊时自述:半个月前连续加班三天,没有合眼。打电话时突然出现左耳发堵、闷胀,伴有耳鸣,一直未缓解。医院给予强的松等药物,服用一段时间后,症状有所缓解,但停药后反复发作。服用本发明的中药组合物制备的药剂5个疗程后,自觉闷胀、耳鸣等症状明显好转;继续服用3个疗程,症状消失,听力恢复正常,治愈。
病例2:孙某,女,44岁。就诊时自述:近2个月来,耳朵总是嗡嗡响,尤其在劳累过后,当时并未重视。近期左耳突然失聪,并伴有头晕、恶心等症状。服用本发明的中药组合物制备的药剂3个疗程,耳中不适感明显减轻,听力显著提高;续服3个疗程后,所有症状消失,听力恢复正常,治愈。

Claims (2)

1.一种治疗突发性耳聋的中药组合物,其特征在于:其中药原料及重量份配比为:石菖蒲10-30份,川芎10-20份,酸枣仁10-20份,鹿茸5-15份,骨碎补10-20份,葛根10-20份,龙眼肉10-20份,陈皮5-15份,枸杞10-20份,山茱萸10-20份,红花5-15份,石蕊10-20份,磁石10-20份,磨盘草10-20份,槐花5-15份,女贞子10-20份,石龙刍10-20份,蛇蜕5-15份,龙齿10-20份,菟丝子10-20份,知母5-15份,乌金草10-20份,甘草5-15份。
2.根据权利要求1所述的一种治疗突发性耳聋的中药组合物,其特征在于:其中药原料及重量份配比为:石菖蒲20份,川芎15份,酸枣仁15份,鹿茸10份,骨碎补15份,葛根15份,龙眼肉15份,陈皮10份,枸杞15份,山茱萸15份,红花10份,石蕊15份,磁石15份,磨盘草15份,槐花10份,女贞子15份,石龙刍15份,蛇蜕10份,龙齿15份,菟丝子15份,知母10份,乌金草15份,甘草10份。
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173371A (zh) * 1997-09-08 1998-02-18 王双 一种治疗耳聋的中药
CN102228580A (zh) * 2011-06-21 2011-11-02 丁见 一种治疗突发性耳聋的中药组合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173371A (zh) * 1997-09-08 1998-02-18 王双 一种治疗耳聋的中药
CN102228580A (zh) * 2011-06-21 2011-11-02 丁见 一种治疗突发性耳聋的中药组合物

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