CN105832987A - 一种治疗突发性耳聋的中药组合物 - Google Patents
一种治疗突发性耳聋的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗突发性耳聋的中药组合物，其中药原料及重量份配比为：石菖蒲10‑30份，川芎10‑20份，酸枣仁10‑20份，鹿茸5‑15份，骨碎补10‑20份，葛根10‑20份，龙眼肉10‑20份，陈皮5‑15份，枸杞10‑20份，山茱萸10‑20份，红花5‑15份，石蕊10‑20份，磁石10‑20份，磨盘草10‑20份，槐花5‑15份，女贞子10‑20份，石龙刍10‑20份，蛇蜕5‑15份，龙齿10‑20份，菟丝子10‑20份，知母5‑15份，乌金草10‑20份，甘草5‑15份。本发明中药组合物具有清热解毒、活血祛淤、通络开窍、补益肝肾的功效，其治疗突发性耳聋疗效显著，作用可靠。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品，尤其是一种治疗突发性耳聋的中药组合物。
背景技术
突发性耳聋是突然的、原因不明的感音神经性听力损失。多发生于单侧耳，亦偶见双耳同时发病或先后发病。常见病因有病毒感染、血管疾病、内淋巴水肿、迷路膜破裂等。临床上一般表现为单侧听力下降，可伴有耳鸣、耳堵塞感、眩晕、呕吐等。目前，临床上治疗突发性耳聋通常采用糖皮质激素、溶栓和抗凝药物治疗，虽然具有一定疗效，但长期服用，易产生依赖性，并且药物的副作用会对人体的免疫系统造成很大的伤害。
中医认为，突发性耳聋是因突发性耳聋多为气滞血淤，耳部经络被淤血所阻塞，清阳之气不能上达于耳窍，使得耳部的正常生理功能减退，从而发生了耳鸣、耳聋等表现。
根据中医理论，针对突发性耳聋的发病机理，以活血祛淤，通络开窍为治则，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中采用糖皮质激素、溶栓和抗凝药物治疗突发性耳聋存在副作用大的不足，本发明提供一种配制方便、疗效显著、作用可靠、无副作用的治疗突发性耳聋的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗突发性耳聋的中药组合物，其特征在于：其中药原料及重量份配比为：石菖蒲10-30份，川芎10-20份，酸枣仁10-20份，鹿茸5-15份，骨碎补10-20份，葛根10-20份，龙眼肉10-20份，陈皮5-15份，枸杞10-20份，山茱萸10-20份，红花5-15份，石蕊10-20份，磁石10-20份，磨盘草10-20份，槐花5-15份，女贞子10-20份，石龙刍10-20份，蛇蜕5-15份，龙齿10-20份，菟丝子10-20份，知母5-15份，乌金草10-20份，甘草5-15份。
本发明的优选技术方案是：一种治疗突发性耳聋的中药组合物，其特征在于：其中药原料及重量份配比为：石菖蒲20份，川芎15份，酸枣仁15份，鹿茸10份，骨碎补15份，葛根15份，龙眼肉15份，陈皮10份，枸杞15份，山茱萸15份，红花10份，石蕊15份，磁石15份，磨盘草15份，槐花10份，女贞子15份，石龙刍15份，蛇蜕10份，龙齿15份，菟丝子15份，知母10份，乌金草15份，甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：石菖蒲具有化痰开窍、化湿行气、祛风利痹、消肿止痛的功效；川芎具有活血祛瘀、行气开郁、祛风止痛的功效；酸枣仁具有养肝敛汗、宁心安神的功效；鹿茸具有壮肾阳、补气血、益精髓、强筋骨的功效；骨碎补具有补肾强骨、续伤止痛的功效；葛根具有发表解肌、升阳透疹、解热生津的功效；龙眼肉具有补益心脾、养血安神的功效；陈皮具有理气健脾、调中利水、燥湿化痰的功效；枸杞具有养肝明目、扶正固本、生精补髓、滋阴补肾、益气安神的功效；山茱萸具有补益肝肾、涩精固脱的功效；红花具有活血通经、散瘀止痛的功效；石蕊具有清热、润燥、凉肝、化痰、利湿的功效；磁石具有平肝潜阳、安神镇惊、聪耳明目、纳气平喘的功效；磨盘草具有疏风清热、化痰止咳、消肿解毒的功效；槐花具有凉血止血、清肝泻火的功效；女贞子具有滋补肝肾、益阴养血的功效；石龙刍具有利水通淋、泄热、安神、凉血止血的功效；蛇蜕具有祛风、定惊、退翳、解毒的功效；龙齿具有镇惊安神、清热除烦的功效；菟丝子具有补肾益精、养肝健脾的功效；知母具有清热泻火、生津润燥的功效；乌金草具有平肝阳、养心安神、养血调经的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍，在作用上相辅相成，具有协同作用，共奏清热解毒、活血祛淤、通络开窍、补益肝肾之功效，对突发性耳聋达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。其遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率91%，治愈率达63.8%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例
1
一种治疗突发性耳聋的中药组合物，其中药原料及重量配比为：石菖蒲20g，川芎15g，酸枣仁15g，鹿茸10g，骨碎补15g，葛根15g，龙眼肉15g，陈皮10g，枸杞15g，山茱萸15g，红花10g，石蕊15g，磁石15g，磨盘草15g，槐花10g，女贞子15g，石龙刍15g，蛇蜕10g，龙齿15g，菟丝子15g，知母10g，乌金草15g，甘草10g。
实施例
2
一种治疗突发性耳聋的中药组合物，其中药原料及重量配比为：石菖蒲30g，川芎10g，酸枣仁20g，鹿茸5g，骨碎补20g，葛根10g，龙眼肉20g，陈皮5g，枸杞20g，山茱萸10g，红花15g，石蕊10g，磁石20g，磨盘草10g，槐花15g，女贞子10g，石龙刍20g，蛇蜕5g，龙齿20g，菟丝子10g，知母15g，乌金草10g，甘草15g。
实施例
3
一种治疗突发性耳聋的中药组合物，其中药原料及重量配比为：石菖蒲10g，川芎20g，酸枣仁10g，鹿茸15g，骨碎补10g，葛根20g，龙眼肉10g，陈皮15g，枸杞10g，山茱萸20g，红花5g，石蕊20g，磁石10g，磨盘草20g，槐花5g，女贞子20g，石龙刍10g，蛇蜕15g，龙齿10g，菟丝子20g，知母5g，乌金草20g，甘草5g。
实施例
4
一种治疗突发性耳聋的中药组合物，其中药原料及重量配比为：石菖蒲23份，川芎12g，酸枣仁18g，鹿茸7g，骨碎补18g，葛根12g，龙眼肉18g，陈皮7g，枸杞18g，山茱萸12g，红花13g，石蕊12g，磁石18g，磨盘草12g，槐花13g，女贞子12g，石龙刍18g，蛇蜕7g，龙齿18g，菟丝子12g，知母13g，乌金草12g，甘草13g。
实施例
5
一种治疗突发性耳聋的中药组合物，其中药原料及重量配比为：石菖蒲17份，川芎18g，酸枣仁12g，鹿茸13g，骨碎补12g，葛根18g，龙眼肉12g，陈皮13g，枸杞12g，山茱萸18g，红花7g，石蕊18g，磁石12g，磨盘草18g，槐花7g，女贞子18g，石龙刍12g，蛇蜕13g，龙齿12g，菟丝子18g，知母7g，乌金草18g，甘草7g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约8厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约6厘米，水沸后煎煮15～20分钟。两次煎煮去渣取汁，合并。
本发明以实施例1所给出的一种治疗突发性耳聋的中药组合物，做临床疗效总结如下：
一、一般性资料：本发明中药组合物应用于临床观察病例47例，其中，男25例，女22例，年龄25～50岁。
二、诊断标准：
1、听力突然下降，1～2天内听力下降达到高峰，多为单耳发病；或伴耳鸣、眩晕；
2、常有恼怒、劳累、感寒等诱因；
3、耳部检查：鼓膜多无明显变化，或有鼓膜混浊；
4、听力检查呈感音神经性聋；
5、应与耳眩晕、耳胀相鉴别。
三、用法用量：临床应用时，一天一剂，水煎两遍取汁约400ml，分早、晚两次温热服用，六天为一疗程。
四、疗效标准：
1、治愈：听力恢复正常；
2、好转：听力提高10分贝以上，耳中不适感减轻；
3、未愈：听力提高不足10分贝。
五、治疗效果：该临床观察病例中，服药5-10个疗程，治愈30例，好转13例，未愈4例。治疗期间未发生毒副作用。
六、典型病例：
病例1：钱某，男，37岁。就诊时自述：半个月前连续加班三天，没有合眼。打电话时突然出现左耳发堵、闷胀，伴有耳鸣，一直未缓解。医院给予强的松等药物，服用一段时间后，症状有所缓解，但停药后反复发作。服用本发明的中药组合物制备的药剂5个疗程后，自觉闷胀、耳鸣等症状明显好转；继续服用3个疗程，症状消失，听力恢复正常，治愈。
病例2：孙某，女，44岁。就诊时自述：近2个月来，耳朵总是嗡嗡响，尤其在劳累过后，当时并未重视。近期左耳突然失聪，并伴有头晕、恶心等症状。服用本发明的中药组合物制备的药剂3个疗程，耳中不适感明显减轻，听力显著提高；续服3个疗程后，所有症状消失，听力恢复正常，治愈。
Claims (2)
1.一种治疗突发性耳聋的中药组合物，其特征在于：其中药原料及重量份配比为：石菖蒲10-30份，川芎10-20份，酸枣仁10-20份，鹿茸5-15份，骨碎补10-20份，葛根10-20份，龙眼肉10-20份，陈皮5-15份，枸杞10-20份，山茱萸10-20份，红花5-15份，石蕊10-20份，磁石10-20份，磨盘草10-20份，槐花5-15份，女贞子10-20份，石龙刍10-20份，蛇蜕5-15份，龙齿10-20份，菟丝子10-20份，知母5-15份，乌金草10-20份，甘草5-15份。
2.根据权利要求1所述的一种治疗突发性耳聋的中药组合物，其特征在于：其中药原料及重量份配比为：石菖蒲20份，川芎15份，酸枣仁15份，鹿茸10份，骨碎补15份，葛根15份，龙眼肉15份，陈皮10份，枸杞15份，山茱萸15份，红花10份，石蕊15份，磁石15份，磨盘草15份，槐花10份，女贞子15份，石龙刍15份，蛇蜕10份，龙齿15份，菟丝子15份，知母10份，乌金草15份，甘草10份。
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| CN102228580A (zh) * | 2011-06-21 | 2011-11-02 | 丁见 | 一种治疗突发性耳聋的中药组合物 |
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