CN105833034A - 一种治疗哮喘的中药组合物 - Google Patents

一种治疗哮喘的中药组合物 Download PDF

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CN105833034A
CN105833034A CN201610354823.3A CN201610354823A CN105833034A CN 105833034 A CN105833034 A CN 105833034A CN 201610354823 A CN201610354823 A CN 201610354823A CN 105833034 A CN105833034 A CN 105833034A
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张晓燕
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Abstract

本发明公开了一种治疗哮喘的中药组合物,其中药原料及重量份配比为:大枣10‑30份,枇杷叶10‑20份,冬凌草10‑20份,红花5‑15份,穿心莲10‑20份,虎杖10‑20份,紫菀10‑20份,陈皮5‑15份,侧柏叶10‑20份,胆南星10‑20份,肉桂5‑15份,百合10‑20份,南沙参10‑20份,麦冬10‑20份,麻黄5‑15份,蒲公英10‑20份,代赭石10‑20份,老鹳草5‑15份,山慈菇10‑20份,旋覆花10‑20份,丹参10‑20份,甘草5‑15份。本发明中药组合物具有健脾补肾、清肺祛痰、止咳定喘、活血散寒的功效,其治疗哮喘疗效显著,作用可靠。

Description

一种 治疗哮喘的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品,尤其是一种治疗哮喘的中药组合物。
背景技术
哮喘病是由外界或人体内存在的某些过敏原(非过敏因素也可引起)引起的支气管的高度敏感性的疾病。由于支气管对刺激物(过敏原)的过度敏感反应,导致支气管发生广泛的可逆性的痉挛、狭窄。临床上通常表现为发作性带有哮鸣音的呼气性呼吸困难,持续数分钟至数小时,经治疗或自行好转。严重的病人可延续数日至数周或在一日内发作数次,病人十分痛苦。哮喘持续时间长了人体出现缺氧的各种症状,如心肌缺氧、大脑缺氧导致心绞痛、心力衰竭、肺性脑病等严重后果。目前,临床上治疗哮喘病主要以糖皮质激素药物为主,虽然具有一定疗效,但长期服用,药物的副作用会对人体产生较大的伤害,容易引发其他并发症。
中医认为,肺为气之主,肾为气之根。当哮喘病发作时,肺道不能主气,肾虚不能纳气,则气逆于上,而发于喘急。脾为生化之源,脾虚生痰,痰阻气道,故见喘咳,气短。因此,哮喘病是肾、肺、脾,三虚之症。。
根据中医理论,针对哮喘的发病机理,以养阴清肺、化虚通窍为治则,进行辩证配伍组方,以达到标本兼治的目的。
发明内容
为了克服现有技术中采用糖皮质激素药物治疗哮喘存在副作用大的不足,本发明提供一种配制方便、疗效显著、作用可靠、无副作用的治疗哮喘的中药组合物。
本发明解决其技术问题所采用的技术方案是:一种治疗哮喘的中药组合物,其特征在于:其中药原料及重量份配比为:大枣10-30份,枇杷叶10-20份,冬凌草10-20份,红花5-15份,穿心莲10-20份,虎杖10-20份,紫菀10-20份,陈皮5-15份,侧柏叶10-20份,胆南星10-20份,肉桂5-15份,百合10-20份,南沙参10-20份,麦冬10-20份,麻黄5-15份,蒲公英10-20份,代赭石10-20份,老鹳草5-15份,山慈菇10-20份,旋覆花10-20份,丹参10-20份,甘草5-15份。
本发明的优选技术方案是:一种治疗哮喘的中药组合物,其特征在于:其中药原料及重量份配比为:大枣20份,枇杷叶15份,冬凌草15份,红花10份,穿心莲15份,虎杖15份,紫菀15份,陈皮10份,侧柏叶15份,胆南星15份,肉桂10份,百合15份,南沙参15份,麦冬15份,麻黄10份,蒲公英15份,代赭石15份,老鹳草10份,山慈菇15份,旋覆花15份,丹参15份,甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下,精选药物组方。本发明中药组合物中:大枣具有补中益气、养血安神的功效;枇杷叶具有清肺止咳、降逆止呕的功效;冬凌草具有清热解毒、活血止痛的功效;红花具有活血通经、散瘀止痛的功效;穿心莲具有清热解毒、凉血消肿的功效;虎杖具有活血散瘀、祛风通络、清热利湿、解毒、止咳化痰的功效;紫菀具有润肺下气、化痰止咳的功效;陈皮具有理气健脾、调中利水、燥湿化痰的功效;侧柏叶具有凉血止血、止咳祛痰、祛风湿、散肿毒的功效;胆南星具有清热化痰、息风定惊的功效;肉桂具有补火助阳、散寒止痛、活血通经的功效;百合具有养阴润肺、清心安神、滋补精血的功效;南沙参具有养阴清肺、化痰、益气的功效;麦冬具有养阴生津、润肺清心的功效;麻黄具有发汗解表、宣肺平喘、利水消肿的功效;蒲公英具有清热解毒、消肿散结、利尿通淋的功效;代赭石具有平肝潜阳、重镇降逆、凉血止血的功效;老鹳草具有祛风湿、通经络、止泻痢的功效;山慈菇具有清热解毒、化痰散结的功效;旋覆花具有降气消痰、行水止呕的功效;丹参具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神的功效;甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍,在作用上相辅相成,具有协同作用,共奏健脾补肾、清肺祛痰、止咳定喘、活血散寒之功效,对哮喘达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料,其配制简便、药源广、成本低。其遵循中医的处方用药原则,各种组分药物采用水煎服用。经临床应用验证,其疗效显著,作用可靠,药性平和,未出现毒副作用,总有效率91%,治愈率达68.2%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗哮喘的中药组合物,其中药原料及重量配比为:大枣20g,枇杷叶15g,冬凌草15g,红花10g,穿心莲15g,虎杖15g,紫菀15g,陈皮10g,侧柏叶15g,胆南星15g,肉桂10g,百合15g,南沙参15g,麦冬15g,麻黄10g,蒲公英15g,代赭石15g,老鹳草10g,山慈菇15g,旋覆花15g,丹参15g,甘草10g。
实施例2
一种治疗哮喘的中药组合物,其中药原料及重量配比为:大枣30g,枇杷叶10g,冬凌草20g,红花5g,穿心莲20g,虎杖10g,紫菀20g,陈皮5g,侧柏叶20g,胆南星10g,肉桂15g,百合10g,南沙参20g,麦冬10g,麻黄15g,蒲公英10g,代赭石20g,老鹳草5g,山慈菇20g,旋覆花10g,丹参20g,甘草5g。
实施例3
一种治疗哮喘的中药组合物,其中药原料及重量配比为:大枣10g,枇杷叶20g,冬凌草10g,红花15g,穿心莲10g,虎杖20g,紫菀10g,陈皮15g,侧柏叶10g,胆南星20g,肉桂5g,百合20g,南沙参10g,麦冬20g,麻黄5g,蒲公英20g,代赭石10g,老鹳草15g,山慈菇10g,旋覆花20g,丹参10g,甘草15g。
实施例4
一种治疗哮喘的中药组合物,其中药原料及重量配比为:大枣23g,枇杷叶12g,冬凌草18g,红花7g,穿心莲18g,虎杖12g,紫菀18g,陈皮7g,侧柏叶18g,胆南星12g,肉桂13g,百合12g,南沙参18g,麦冬12g,麻黄13g,蒲公英12g,代赭石18g,老鹳草7g,山慈菇18g,旋覆花12g,丹参18g,甘草7g。
实施例5
一种治疗哮喘的中药组合物,其中药原料及重量配比为:大枣17g,枇杷叶18g,冬凌草12g,红花13g,穿心莲12g,虎杖18g,紫菀12g,陈皮13g,侧柏叶12g,胆南星18g,肉桂7g,百合18g,南沙参12g,麦冬18g,麻黄7g,蒲公英18g,代赭石12g,老鹳草13g,山慈菇12g,旋覆花18g,丹参12g,甘草13g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中,加冷水漫过药面,浸泡15~20分钟,再加水没过药面约8厘米,进行第一次煎煮,未沸前采用武火煎煮,沸后用文火煎煮20~30分钟;第二次煎煮,加水没过药面约6厘米,水沸后煎煮15~20分钟。两次煎煮去渣取汁,合并。
本发明以实施例1所给出的一种治疗哮喘的中药组合物,做临床疗效总结如下:
一、一般性资料:本发明中药组合物应用于临床观察病例66例,其中男30例,女36例,年龄5~75岁。
二、诊断标准:
1、发作前常有喷嚏、咳嗽等先兆症状,或夜间突然发作;发作时喉间哮鸣,呼吸困难,咯痰不爽,甚则不能平卧,烦躁不安等;
2、常因气候转变、受凉,或接触某些过敏物质等因素诱发;
3、可有婴儿期湿疹史,或家族过敏史;
4、心肺听诊:两肺满布哮鸣音,呼气延长,或闻及湿罗音,心率增快;
5、支气管哮喘,血白细胞总数正常,嗜酸性粒细胞可增高,可疑变应原皮肤试验常呈阳性;伴肺部感染时,血白细胞总数及中性粒细胞可增高。
三、用法用量:临床应用时,一天一剂,水煎两遍取汁约400ml,分早、晚两次温热服用,五天为一疗程。
四、疗效标准:
1、治愈:哮喘平息,听诊两肺哮鸣音消失;
2、好转:哮喘减轻,听诊偶闻哮鸣音;
3、未愈:哮喘发作症状无改善。
五、治疗效果:该临床观察病例中,服药5-12个疗程,治愈45例,好转15例,未愈6例。治疗期间未发生毒副作用。
六、典型病例:
病例1:李某,男,28岁。自述2周前出现咽痛,咳嗽,伴有发热,口服感冒药后发热症状明显改善,但咳嗽不见好转。3天前夜间突然出现呼吸困难,喉间哮鸣音,烦躁不安。服用本发明的中药组合物制备的药剂4个疗程后,自觉哮喘好转,呼吸顺畅;继续服用3个疗程,症状消失,治愈。
病例2:孙某,女,50岁。自述患有多年哮喘病,发作时呼吸困难,胸闷气短,不能平卧。期间服用过很多西药治疗哮喘,病情总是反复发作。服用本发明的中药组合物制备的药剂5个疗程,发作频率明显降低,且发作时各症状明显好转;续服5个疗程后,各症状消失,治愈。回访未见复发。

Claims (2)

1. 一种治疗哮喘的中药组合物,其特征在于:其中药原料及重量份配比为:大枣10-30份,枇杷叶10-20份,冬凌草10-20份,红花5-15份,穿心莲10-20份,虎杖10-20份,紫菀10-20份,陈皮5-15份,侧柏叶10-20份,胆南星10-20份,肉桂5-15份,百合10-20份,南沙参10-20份,麦冬10-20份,麻黄5-15份,蒲公英10-20份,代赭石10-20份,老鹳草5-15份,山慈菇10-20份,旋覆花10-20份,丹参10-20份,甘草5-15份。
2. 根据权利要求1所述的一种治疗哮喘的中药组合物,其特征在于:其中药原料及重量份配比为:大枣20份,枇杷叶15份,冬凌草15份,红花10份,穿心莲15份,虎杖15份,紫菀15份,陈皮10份,侧柏叶15份,胆南星15份,肉桂10份,百合15份,南沙参15份,麦冬15份,麻黄10份,蒲公英15份,代赭石15份,老鹳草10份,山慈菇15份,旋覆花15份,丹参15份,甘草10份。
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CN107582834A (zh) * 2017-09-20 2018-01-16 河南中医药大学 一种治疗虚喘的中药组合物
WO2022061420A1 (en) * 2020-09-28 2022-03-31 Apex Biotech Research Pty Ltd Formulations comprising botanical extracts

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CN103877535A (zh) * 2014-02-20 2014-06-25 何成元 一种治疗哮喘的中药组合物

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CN103877535A (zh) * 2014-02-20 2014-06-25 何成元 一种治疗哮喘的中药组合物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582834A (zh) * 2017-09-20 2018-01-16 河南中医药大学 一种治疗虚喘的中药组合物
WO2022061420A1 (en) * 2020-09-28 2022-03-31 Apex Biotech Research Pty Ltd Formulations comprising botanical extracts

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