CN105477330A - 一种治疗心律失常的中药组合物 - Google Patents

一种治疗心律失常的中药组合物 Download PDF

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CN105477330A
CN105477330A CN201610041000.5A CN201610041000A CN105477330A CN 105477330 A CN105477330 A CN 105477330A CN 201610041000 A CN201610041000 A CN 201610041000A CN 105477330 A CN105477330 A CN 105477330A
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王浩
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Abstract

本发明公开了一种治疗心律失常的中药组合物，其中药原料及重量份配比为：太子参10-30份，麦冬10-20份，女贞子10-20份，麻黄5-15份，白蒺藜10-30份，五加皮5-15份，桂枝10-20份，莲子10-20份，马勃5-15份，乳香5-15份，青风藤10-20份，旱莲草10-20份，栝楼皮5-15份，柏子仁10-30份，五味子10-20份，红花5-15份，党参10-20份，百合10-20份，佛手5-15份，鹿衔草10-20份，黄精10-20份，檀香10-30份，龙齿10-20份，菊花10-20份，甘草5-15份。本发明中药组合物具有健脾益肾、舒肝养心、益气活血、通脉祛瘀的功效，其治疗心律失常疗效显著，作用可靠。

Description

一种治疗心律失常的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品，尤其是一种治疗心律失常的中药组合物。
背景技术
心律失常是由于窦房结激动异常或激动产生于窦房结以外，激动的传导缓慢、阻滞或经异常通道传导，即心脏活动的起源和/或传导障碍导致心脏搏动的频率和/或节律异常。心律失常是心血管疾病中重要的一组疾病,它可单独发病亦可与心血管病伴发,可突然发作而致猝死，亦可持续累及心脏而衰竭。目前，对心律失常可分为一般治疗和常用药物治疗。一般治疗有通过异丙肾上腺素、阿托品等西药增加心肌自律性和/或加速传导，或通过心脏起搏器、电除颤、射频消融等非药物疗法治疗，其存在疗效不理的不足。药物治疗主要有钠通道阻滞药、β肾上腺素受体阻断药、延长复极过程药、钙拮抗药四种，但是所有抗心律失常药物长期服用均有不同程度的副作用，严重的可引起室性心律失常或心脏传导阻滞而致命。因此，服用抗心律失常西药存在着用药安全问题。
中医认为，心律失常属中医心悸、怔忡、晕厥范畴，其病因主要为“瘀”、“热”、“虚”三个方面，“瘀”为淤血内阻，心脉不畅；“热”为血分蕴热，与淤胶结难解；“虚”为气虚、阴虚，涉及心、脾、肝、肾四脏。故宜以补脾补肾、平肝宁心、通脉祛瘀为治则。
根据中医理论，针对心律失常的发病机理，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有一般治疗心律失常存在疗效不理想、西药治疗存在着用药不安全的不足，本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗心律失常的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗心律失常的中药组合物，其特征在于：其中药原料及重量份配比为：太子参10-30份，麦冬10-20份，女贞子10-20份，麻黄5-15份，白蒺藜10-30份，五加皮5-15份，桂枝10-20份，莲子10-20份，马勃5-15份，乳香5-15份，青风藤10-20份，旱莲草10-20份，栝楼皮5-15份，柏子仁10-30份，五味子10-20份，红花5-15份，党参10-20份，百合10-20份，佛手5-15份，鹿衔草10-20份，黄精10-20份，檀香10-30份，龙齿10-20份，菊花10-20份，甘草5-15份。
本发明的优选技术方案是：一种治疗心律失常的中药组合物，其特征在于：其中药原料及重量份配比为：太子参20份，麦冬15份，女贞子15份，麻黄10份，白蒺藜20份，五加皮10份，桂枝15份，莲子15份，马勃10份，乳香10份，青风藤15份，旱莲草15份，栝楼皮10份，柏子仁20份，五味子15份，红花10份，党参15份，百合15份，佛手10份，鹿衔草15份，黄精15份，檀香20份，龙齿15份，菊花15份，甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：太子参具有益气健脾、生津润肺的功效；麦冬具有养阴生津、润肺清心的功效；女贞子具有滋补肝肾、益阴养血之功效；麻黄具有发汗解表、宣肺平喘、利水消肿的功效；白蒺藜具有平肝解郁、祛风明目的功效；五加皮具有祛风湿、补肝肾、强筋骨的功效；桂枝具有发汗解肌、温经通脉、助阳化气、散寒止痛的功效；莲子具有补脾止泻、养心益肾功效；马勃具有清热解毒、利咽、止血的功效；乳香具有活血,行气、止痛的功效；青风藤具有祛风湿、通经络、利小便的功效；旱莲草具有养肝益肾、凉血止血的功效；栝楼皮具有润肺化痰、利气宽胸的功效；柏子仁具有养心安神、滋阴养血的功效；五味子具有收敛固涩、益气生津、补肾宁心的功效；红花具有活血通经、散瘀止痛的功效；党参具有补中益气、健脾益肺的功效；百合具有养阴润肺、清心安神、滋补精血的功效；佛手具有舒肝理气、和胃止痛的功效；鹿衔草具有补虚、益肾、祛风除湿、活血调经、补肾强骨、止咳、止血的功效；黄精具有滋肾润肺、补脾益气、养阴生津的功效；檀香具有理气、和胃的功效；龙齿具有镇惊安神、清热除烦的功效；菊花具有疏散风热、平肝明目、清热解毒的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍，在作用上相辅相成，具有协同作用，共奏健脾益肾、舒肝养心、益气活血、通脉祛瘀之功效，对心律失常达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。其遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率90%，治愈率达61.3%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗心律失常的中药组合物，其中药原料及重量配比为：太子参20g，麦冬15g，女贞子15g，麻黄10g，白蒺藜20g，五加皮10g，桂枝15g，莲子15g，马勃10g，乳香10g，青风藤15g，旱莲草15g，栝楼皮10g，柏子仁20g，五味子15g，红花10g，党参15g，百合15g，佛手10g，鹿衔草15g，黄精15g，檀香20g，龙齿15g，菊花15g，甘草10g。
实施例2
一种治疗心律失常的中药组合物，其中药原料及重量配比为：太子参10g，麦冬20g，女贞子10g，麻黄15g，白蒺藜10g，五加皮15g，桂枝10g，莲子20g，马勃5g，乳香15g，青风藤10g，旱莲草20g，栝楼皮5g，柏子仁30g，五味子10g，红花15g，党参10g，百合20g，佛手5g，鹿衔草20g，黄精10g，檀香30g，龙齿10g，菊花20g，甘草5g。
实施例3
一种治疗心律失常的中药组合物，其中药原料及重量配比为：太子参30g，麦冬10g，女贞子20g，麻黄5g，白蒺藜30g，五加皮5g，桂枝20g，莲子10g，马勃15g，乳香5g，青风藤20g，旱莲草10g，栝楼皮15g，柏子仁10g，五味子20g，红花5g，党参20g，百合10g，佛手15g，鹿衔草10g，黄精20g，檀香10g，龙齿20g，菊花10g，甘草15g。
实施例4
一种治疗心律失常的中药组合物，其中药原料及重量配比为：太子参15g，麦冬18g，女贞子12g，麻黄13g，白蒺藜15g，五加皮13g，桂枝12g，莲子18g，马勃8g，乳香13g，青风藤12g，旱莲草18g，栝楼皮8g，柏子仁25g，五味子12g，红花13g，党参12g，百合18g，佛手8g，鹿衔草18g，黄精12g，檀香25g，龙齿12g，菊花18g，甘草8g。
实施例5
一种治疗心律失常的中药组合物，其中药原料及重量配比为：太子参25g，麦冬12g，女贞子18g，麻黄8g，白蒺藜25g，五加皮8g，桂枝18g，莲子12g，马勃13g，乳香8g，青风藤18g，旱莲草12g，栝楼皮13g，柏子仁15g，五味子18g，红花8g，党参18g，百合12g，佛手13g，鹿衔草12g，黄精18g，檀香15g，龙齿18g，菊花12g，甘草13g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约8厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约6厘米，水沸后煎煮15～20分钟。两次煎煮去渣取汁，合并。
本发明以实施例1所给出的一种治疗心律失常的中药组合物，做临床疗效总结如下：
一、一般性资料：本发明中药组合物应用于临床观察病例80例，其中男44例，女36例，年龄12～78岁。病程最短者3个月，最长者达10年，平均2年。
二、临床症状：
头昏乏力、心悸不安、胸压不适，多伴有昏厥、气急失眠、休克等症状。
三、用法用量：临床应用时，一天一剂，水煎两遍取汁约400ml，分早、晚两次饭前半小时温热服用，五天一疗程。服药期间忌食生冷、辛辣之物。
四、疗效标准：
1、痊愈：症状消失，心电图正常；
2、显效：临床症状明显改善或消失，心电图正常或基本正常；
3、有效；临床症状有所减轻，心电图较之前有所改善；
4、无效：临床症状无改善，心电图亦无改变。
五、治疗效果：该临床观察病例中，服药2-12个疗程，痊愈49例，显效16例，有效7例，无效8例。治疗期间未发生毒副作用。
六、典型病例：
病例1：黄某，男，16岁。体态瘦弱，疲倦怠动，脸颊异红，额头有密集青春痘，近期出现心慌、气短、头痛等症状，并伴有恶心欲吐，入睡难，烦躁多梦等。心电图检查诊为：心律失常。服用本发明的中药组合物2个疗程后脸色正常，青春痘结痂减少，心慌、气短、头痛的症状明显改善；继续服用2个疗程，青春痘消失，精神良好，所有症状完全消失，痊愈。
病例2：钱某，女，52岁。患者自述：近一个月心悸胸闷，气短乏力，食欲不佳，有时恶心欲吐，时有胸痛，痛如针刺，向背后及上肢放射。诊见：舌质红，苔黄厚，脉细沉无力。心电图检查诊为：心律失常。服用本发明中药组合物制备的药剂2个疗程后，胸闷心悸症状明显改善，食欲见佳，胸痛发作频率降低；继续服用3个疗程，各症状消失，心电图检查正常，痊愈。

Claims (2)

1.一种治疗心律失常的中药组合物，其特征在于：其中药原料及重量份配比为：太子参10-30份，麦冬10-20份，女贞子10-20份，麻黄5-15份，白蒺藜10-30份，五加皮5-15份，桂枝10-20份，莲子10-20份，马勃5-15份，乳香5-15份，青风藤10-20份，旱莲草10-20份，栝楼皮5-15份，柏子仁10-30份，五味子10-20份，红花5-15份，党参10-20份，百合10-20份，佛手5-15份，鹿衔草10-20份，黄精10-20份，檀香10-30份，龙齿10-20份，菊花10-20份，甘草5-15份。
2.根据权利要求1所述的一种治疗心律失常的中药组合物，其特征在于：其中药原料及重量份配比为：太子参20份，麦冬15份，女贞子15份，麻黄10份，白蒺藜20份，五加皮10份，桂枝15份，莲子15份，马勃10份，乳香10份，青风藤15份，旱莲草15份，栝楼皮10份，柏子仁20份，五味子15份，红花10份，党参15份，百合15份，佛手10份，鹿衔草15份，黄精15份，檀香20份，龙齿15份，菊花15份，甘草10份。
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