CN105832585A - Traditional Chinese medicine crease-resistant face cream and manufacturing method thereof - Google Patents

Abstract

The invention discloses a manufacturing method of traditional Chinese medicine crease-resistant face cream. The manufacturing method comprises a, processing radix polygonati officinalis and carrying out extraction to obtain a component 1, b, taking mint, pericarpium citri reticulatae, angelica root and bletilla striata, carrying out vaporization crystallization through a distillation method, carrying out crushing and carrying out fine screening to obtain a component 2, c, extracting other medical raw materials through ethanol twice and merging and concentrating the extract to obtain a component 3, and d, blending the components 1, 2 and 3, blending the mixture and matrix propolis, carrying out sterilization, carrying out canning and carrying out refrigeration. The face cream can stimulate deep skin replacement. Radix polygonati officinalis can tighten a joint of epidermis and dermis, soften skin, relieves facial laxity, make skin smooth and elastic, promote collagen formation in a dermis layer, promotes fibrous protein regeneration and reconnection and realize tight and smooth skin. The face cream helps damaged tissue healing and skin tightening.

Description

Traditional Chinese Medicine Anti drawn grain frost manufacture method and facial cream thereof

Technical field

The present invention relates to containing the beauty treatment preparation deriving from plant, animal or mineral component, particularly to a kind of crease-resistant facial cream of Rhizoma Polygonati Odorati and preparation method thereof.

Background technology

Chinese medicine beauty treatment is under the guidance of Chinese medicine rationale, by using beauty treatment oral medicinal herb or the outer a kind of method being used for recovering or improve the physiological function of body.Interior oral administration, from internal benefiting vital QI and blood, regulation function, makes people's QI and blood abundant, radiant.Outer usage is to use medicine to directly act on body surface local, and it utilizes the performance of medicine, makes QI and blood flowing, unimpeded through gas, with the effect of the health care that reaches to improve looks.Compared with chemical toilet, Chinese medicine beauty treatment has outstanding feature and advantage.One is that Chinese medicine beauty treatment combines together with Chinese medicine, has the most functional, and its principle, as Chinese medicine, focuses on overall conditioning, emphasizes first to nurse one's health inherence, then will shape in outward, therefore, cosmetic result persistently, stablize.Two is with theory of Chinese medical science for instructing, and has theory of Chinese medical science feature, such as organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, property theory, compound compatibility, has the thinking different from modern cosmetics.Three is to have pure natural property, and Chinese medicine relatively synthetic in terms of cosmetic sunscreen has uniqueness and significant advantage, has the features such as nontoxic, harmless, the most carcinogenic.

The beauty treatment Chinese medicine summing up out up to now kind more than totally 300, nearly thousand kinds of prescription of improving looks, its elite can be that modern beauty provides effective natural drug therapy.Radix Angelicae Sinensis, Radix Ginseng, the Radix Angelicae Dahuricae, Semen Coicis, Semen Armeniacae Amarum, Semen Persicae, Fructus Lycii, Cortex Phellodendri, Flos Chrysanthemi, Rhizoma Typhonii, Rhizoma Chuanxiong, Bulbus Lilii, Radix Salviae Miltiorrhizae, Semen Euryales etc. are all more common beauty treatment Chinese medicine.Wherein Radix Angelicae Sinensis is warm in nature, sweet in the mouth, pungent.There is the effect invigorated blood circulation, enrich blood, blood circulation, skin nutrition can be accelerated, make skin health ruddy.Radix Ginseng contains volatile oil, ginsenoside, polysaccharide, multiple low molecular peptide aminoacid, the composition such as vitamin B group, vitamin C, can improve the blood circulation of local skin, strengthen the supply of skin-nourishing material, promote the metabolism of skin, keep the bright and clean and moist of skin, thus the effect of delay skin aging can be played.

Margarita is in all age always the skin protection conditioning skin and losing good merchantable brand that people like, skin can be made fine and smooth, and color is ruddy, without wrinkle.Flos Rosae Chinensis is the most often swallowed with conditioning skin and losing according to passing Qing Dynasty the Empress Dowager.Rhizomadioscoreae, Semen Nelumbinis, Bulbus Lilii, Fructus Jujubae all energy strengthening the spleen and nourishing the stomach, nourishing blood to tranquillize the mind so that the moist fitness of skin.The promoting blood flow and remove blood stasis drug such as Flos Carthami, Semen Persicae has and improves skin microcirculation effect, so that the QI and blood of people fills Sheng, radiant.Radix Notoginseng, Radix Salviae Miltiorrhizae can moisten and cleaning skin, dispel skin chloasma and black speck, suppress seborrheic dermatitis, skin is had delaying senility function.Application Chinese medicine is improved looks, and for oral administration have decoction, powder, unguentum, a medicated wine, and medicinal diet for beautifying etc..Life traditional Chinese medicinal meals cosmetic applications is more, and this is theory based on the traditional Chinese medical science " doctor food homology, integration of edible and medicinal herbs " in fact, and the medicine selecting some effect relevant becomes food with food formulation, to reach beauty treatment and the double effects of health care.External is washed, is smoked, and facial film applies, more with facial film application again.

Rhizoma Polygonati Odorati, formal name used at school: Polygonatum odoratum (Mill.) Druce, for Liliaceae herbaceos perennial.Rhizome horizontal walk, meat yellow-white, close raw most fibrous roots.Blade face is green, below Lycoperdon polymorphum Vitt.Flower axil is raw, usual 1～3 pieces bunches of lifes.Originate in In Southwest China, but wild distribution is the widest.Cold-resistant, the most resistance to the moon, like wet environment, suitable growth is in the chesson abundant containing humus." stem is tetanic, like bamboo arrow shaft, has joint for Collective Notes to the Canon of Materia medica cloud." therefore have the name of Rhizoma Polygonati Odorati.The rhizome of plant can hyoscine, Chinese medicine name is also Rhizoma Polygonati Odorati, excavates autumn, cleans, and shines to after softness, repeatedly rubs, and dry in the sun, to without hard-core, is dried, or after steaming thoroughly, rubs to translucent, dry, cut sheet or section use.Rhizoma Polygonati Odorati extraction flavonoid substances is combined a kind of novel substance of formation and washes pancreas sugar element (cics) clearly with Folium Mori extract deoxynojirimycin, has blood sugar lowering, blood fat, blood pressure etc. and acts on.

Rhizoma Polygonati Odorati tool yin nourishing, moisturize, heat clearing away, promote the production of body fluid, the effect such as cough-relieving.As tonic, cure mainly the diseases such as consumption of YIN caused by febrile disease, deficiency-heat cough caused by dryness, heart disease, diabetes, tuberculosis, and high-grade nourishing food, delicacies and beverage can be made, with health role, it is worth vast farmers plantation.

Rhizoma Polygonati Odorati root stock (odoratan) Han Rhizoma Polygonati Odorati mucopolysaccharide, is made up of D-Fructose, D-MANNOSE, D-Glucose and galacturonic acid, and mol ratio is 6: 3: 1: 1.5；Rhizoma Polygonati Odorati levan (polygonatum-fructan) A, B, C, D, sugar consist of fructose (%): glucose (%) (97.5:2.6,96.2:3.8,95.3:4.8,90.4:9.6), AzeOH (azetidine-2-carboxylic acid).The also spiral shell sterol Han Rhizoma Polygonati (polyspirostanol) Poa, Rhizoma Polygonati spiral shell sterol glycoside (poly-spirostanoside) Pob, Poc, PO1, PO2, PO3, PO4, PO5, Rhizoma Polygonati furan sterol glycoside (polyfuroside), the steroid such as Rhizoma Polygonati furan sterol glycoside Poc, Pod, PO6, PO7, PO8 and PO9.PO2 Yu Pob has identical structure, is 25-R, S three-dimensional heterogeneous mixture, and simply R/S ratio is different；PO3 is the mixture of Poc extremely 25-R.

Rhizoma Polygonati Odorati yin nourishing, moisturizes, and relieving restlessness is quenched the thirst.Controlling calentura the moon wound, excessive thirst of coughing, deficient fever, rapid digestion of food is the most hungry, frequent micturition." herbal classic ": " main apoplexy sudden high fever, it is impossible to shake falls muscle knot meat, various symptoms and signs of deficiency.Clothes go dark complexion wild for a long time, and good color is moist." " not Lu ": " main stagnation of QI in chest and abdomen deficiency-heat, noxious dampness lumbago, stem invasion by pathogenic cold, and the rotten lacrimation of the ophthalmalgia corner of the eyes.Disease cold and heat when " " property of medicine opinion ": " is main, interior tonifying for the deficiency, goes asthenia exopathogenic heat, headache uneasiness." supplement to the Herbal: " is main clever, adjusts vim and vigour, makes us strong." " Japan hanako materia medica ": " relieving restlessness is vexed, quenches the thirst, and moistens cardiopulmonary, mends five kinds of strain and seven kinds of impairment, deficient, and waist foot pain pain, sky row is fanatical." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " fills blood, invigorating middle warmer spleen invigorating." " detailed outline ": " main air temperature spontaneous perspiration is scorching hot, and malaria with general debility cold and heat, and taste void is weary, man's frequent micturition, consumption of essence, and all are deficient." " Guangxi Chinese medicinal herbal ": " nourishing YIN and clearing away lung-heat is moisturized.Control the deficiency of YIN, hyperhidrosis, cough caused by dryness, consumptive lung disease.″

Rhizoma Polygonati Odorati also has fertile Rhizoma Polygonati Odorati, and bright Rhizoma Polygonati Odorati, outside tail ginseng grade.This product sweet in the mouth, greasiness, soft and moist edible, it is longer than yin nourishing, mainly act on taste, therefore take not imapirment of the spleen and stomach for a long time, cure mainly the few expectorant of the dry cough caused by deficiency of lung-YIN, pharynx dryness of the tongue and epidemic febrile disease later stage, or because hyperpyrexia consumption impairment of body fluid liquid the diseases such as Tianjin of occurring is few the most thirsty, inappetence, stomach discomfort.This product is mended and oiliness, cold the driest, therefore has " tonification the five internal organs, nourish QI and blood, flat benefit and moisten, hold concurrently except wind heat " merit, have and nourish the calm neural and effect of heart tonifying.It is applicable to cardiopalmus, angina pectoris.Confirming through modern medicine study, Rhizoma Polygonati Odorati also has hypoglycemic activity, also has moist skin, dissipation skin chronic inflammatory disease and treatment to get injured by a fall the effect sprained.

The invention discloses a kind of Chinese medicine anti-wrinkle composition, be made up of Chinese medicinal ingredients.Wherein, Radix Angelicae Sinensis promotes skin metabolism, skin lightening of invigorating blood circulation；The Radix Angelicae Dahuricae, Poria, Semen Armeniacae Amarum whitening and moistening skin；Pseudobulbus Bletillae (Rhizoma Bletillae) consolidation smoothing wrinkle；Flos Rosae Chinensis has whitening convergence granulation promoting, promotes cell regeneration and effect of cicatrix healing, is the treasure of whitening and skin-protecting；Herba Centellae energy aging resistance, consolidation pore, effect except microgroove, be also the anti-ageing holy product of beauty treatment.There is effect that skin lightening of invigorating blood circulation, whitening are wrinkle resistant, it is adaptable to person in middle and old age, the skin that aging is lax, wrinkle gathers.

Summary of the invention

The technical problem to be solved is, Chinese medicine beauty treatment is under the guidance of Chinese medicine rationale, by using beauty treatment oral medicinal herb or the outer a kind of method being used for recovering or improve the physiological function of body.Interior oral administration, from internal benefiting vital QI and blood, regulation function, makes people's QI and blood abundant, radiant.Outer usage is to use medicine to directly act on body surface local, and it utilizes the performance of medicine, makes QI and blood flowing, unimpeded through gas, with the effect of the health care that reaches to improve looks.Compared with chemical toilet, Chinese medicine beauty treatment has outstanding feature and advantage.Rhizoma Polygonati Odorati energy aging resistance, consolidation pore, effect except microgroove, be also the anti-ageing holy product of beauty treatment.There is effect that skin lightening of invigorating blood circulation, whitening are wrinkle resistant, it is adaptable to person in middle and old age, the skin that aging is lax, wrinkle gathers.

For solving these technical barriers, the invention provides a kind of crease-resistant facial cream of Rhizoma Polygonati Odorati, its described crease-resistant facial cream can include the crude drug of following parts by weight: Rhizoma Polygonati Odorati 10～50 parts, Herba Centellae 10～20 parts, the Radix Astragali 10～20 parts, Herba Leonuri 10～20 parts, Semen Lablab Album 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Pericarpium Citri Reticulatae 10～20 parts, Radix Trichosanthis 10～20 parts, Flos Carthami 10～20 parts, the Radix Paeoniae Alba 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Flos Nelumbinis 10～20 parts, Radix Ampelopsis 10～20 parts, the Radix Angelicae Dahuricae 10～20 parts, Flos Rosae Chinensis 10～20 parts, Flos Inulae 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～20 parts, Flos Pelargonii 10～20 parts, Flos Albiziae 10～20 parts.

The crease-resistant facial cream of described Rhizoma Polygonati Odorati, its described crease-resistant facial cream can also include the crude drug of following parts by weight: Rhizoma Polygonati Odorati 10～30 parts, Herba Centellae 10～15 parts, the Radix Astragali 10～15 parts, Herba Leonuri 10～15 parts, Semen Lablab Album 10～15 parts, Radix Salviae Miltiorrhizae 10～15 parts, Pericarpium Citri Reticulatae 10～15 parts, Radix Trichosanthis 10～15 parts, Flos Carthami 10～15 parts, the Radix Paeoniae Alba 10～15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15 parts, Herba Menthae 10～20 parts, Flos Nelumbinis 10～20 parts, Radix Ampelopsis 10～20 parts, the Radix Angelicae Dahuricae 10～20 parts, Flos Rosae Chinensis 10～20 parts, Flos Inulae 10～20 parts, Radix Angelicae Sinensis 10～20 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～20 parts, Flos Pelargonii 10～20 parts, Flos Albiziae 10～20 parts.

The crease-resistant facial cream of described Rhizoma Polygonati Odorati, its described crease-resistant facial cream can also include the crude drug of following parts by weight: Rhizoma Polygonati Odorati 10～40 parts, Herba Centellae 10～20 parts, the Radix Astragali 10～20 parts, Herba Leonuri 10～20 parts, Semen Lablab Album 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Pericarpium Citri Reticulatae 10～20 parts, Radix Trichosanthis 10～20 parts, Flos Carthami 10～20 parts, the Radix Paeoniae Alba 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～15 parts, Flos Nelumbinis 10～15 parts, Radix Ampelopsis 10～15 parts, the Radix Angelicae Dahuricae 10～15 parts, Flos Rosae Chinensis 10～15 parts, Flos Inulae 10～15 parts, Radix Angelicae Sinensis 10～15 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～20 parts, Flos Pelargonii 10～20 parts, Flos Albiziae 10～20 parts.

For solving above-mentioned technical problem, the present invention also provides for the manufacture method of a kind of crease-resistant facial cream of described Rhizoma Polygonati Odorati, and its described manufacture method comprises the following steps:

A. the making of Rhizoma Polygonati Odorati, extraction, as component 1；

B. take Herba Menthae, Pericarpium Citri Reticulatae, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 2；

C. by remaining crude drug ethanol extraction 2 times, concentrated extracting solution is merged, as component 3；

D. add substrate propolis with component 3 after component 1, component 2 being mixed to be in harmonious proportion, cold preservation after sterilization tinning.

In described step a, the Rhizoma Polygonati Odorati chopping will plucked autumn in summer can be taken, cross 80-100 mesh sieve.

In described step a, may further include the step of extraction, be placed in lid stainless steel cask by the Rhizoma Polygonati Odorati of chopping, add 70% ethanol, quality is 0.8-1 times of coarse powder, stirs, moistening airtight placement more than 1 hour, makes fully to expand；By bottom percolator filter plate gauze bag parcel pave after again the drug sample after moistening expansion is mixed pine do dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, medicated powder loads 2/3 eminence that must not exceed percolator；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow per minute 2～3ml, filtrate puts into liquid container, and pours ethanol during emptying into liquid container；Being merged by percolate and stand, heating is concentrated into paste, stand for standby use, becomes component 1.

In described step b, Herba Menthae, Pericarpium Citri Reticulatae, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation can be taken and be vaporized into crystallization, pulverize 120-150 mesh dusting cover stand-by, as component 2.

In described step c, remaining raw material described can be added soak with ethanol 4-6 hour accounting for its quality 5-10 times amount, heating extraction 2 times, 1-2 hour every time, united extraction liquid, supernatant is removed after standing, then 100-120 mesh filters, the ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming again, the filtrate of 1.25 when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, standing is put in economic benefits and social benefits vacuum concentrator and is mixed, and first concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, then inserts 0～5 DEG C of deepfreeze 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml extractum Han 0.1g, as component 3.

In described step d, three kinds of component mixing above-mentioned steps can extracted, stir, heating, mediation substrate, substrate selects propolis, ultraviolet sterilization bottling cold preservation.

The using method of the crease-resistant facial cream of described Rhizoma Polygonati Odorati, owing to this anti-wrinkle paste is without preservative, so necessary cold preservation, every time the most just before going to bed after face cleaning, by anti-wrinkling cream uniform application in face, and by middle finger finger belly face message 15-20 minute, after fully absorbing to it, getting up early in second day washes away.

Rhizoma Polygonati Odorati energy aging resistance, consolidation pore, effect except microgroove, be also the anti-ageing holy product of beauty treatment.The beautiful face that the Empress Dowager is famous dissipates and just comprises Rhizoma Polygonati Odorati." herbal classic " carries it: " main apoplexy sudden high fever, it is impossible to shake falls muscle knot meat, various symptoms and signs of deficiency.Clothes go dark complexion wild for a long time, and good color is moist.There is effect that skin lightening of invigorating blood circulation, whitening are wrinkle resistant, it is adaptable to person in middle and old age, the skin that aging is lax, wrinkle gathers.The present invention is with reference to the achievement of Chinese medicine pharmacological research at all times, screening Glycerin, inrigorating qi and promoting blood circulation, liver heat removing and eyesight improving, nourishing liver and kidney, improving acuity of vision and removing nebula, suppressing the hyperactive liver and subsiding YANG, detumescence are except the natural Chinese medicine of water, strengthening vital QI to eliminate pathogenic factors, and purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, the metabolism function of regulation human body, improves human facial skin's blood circulation, thus reaches wrinkle, compact skin, eliminate skin texture, detumescence blood stasis dispelling, fatigue alleviating, the skin around the eyes that compacts, desalination eye pouch, reduce wrinkle, beautify the purpose of appearance.The present invention can stimulate deep skin cell to substitute.The present invention can make skin limber up, and contributes to solving cutis laxa phenomenon, makes skin smooth flexible；Promoting that in skin corium, collagen protein is formed, and makes fibrin regenerate, reconnect is got up, and makes skin reach smooth effect of compacting.Also assist in impaired organization healing and consolidation skin.

Detailed description of the invention

Chinese medicine beauty treatment is under the guidance of Chinese medicine rationale, by using beauty treatment oral medicinal herb or the outer a kind of method being used for recovering or improve the physiological function of body.Interior oral administration, from internal benefiting vital QI and blood, regulation function, makes people's QI and blood abundant, radiant.Outer usage is to use medicine to directly act on body surface local, and it utilizes the performance of medicine, makes QI and blood flowing, unimpeded through gas, with the effect of the health care that reaches to improve looks.Compared with chemical toilet, Chinese medicine beauty treatment has outstanding feature and advantage.One is that Chinese medicine beauty treatment combines together with Chinese medicine, has the most functional, and its principle, as Chinese medicine, focuses on overall conditioning, emphasizes first to nurse one's health inherence, then will shape in outward, therefore, cosmetic result persistently, stablize.Two is with theory of Chinese medical science for instructing, and has theory of Chinese medical science feature, such as organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, property theory, compound compatibility, has the thinking different from modern cosmetics.Three is to have pure natural property, and Chinese medicine relatively synthetic in terms of cosmetic sunscreen has uniqueness and significant advantage, has the features such as nontoxic, harmless, the most carcinogenic.

The beauty treatment Chinese medicine summing up out up to now kind more than totally 300, nearly thousand kinds of prescription of improving looks, its elite can be that modern beauty provides effective natural drug therapy.Radix Angelicae Sinensis, Radix Ginseng, the Radix Angelicae Dahuricae, Semen Coicis, Semen Armeniacae Amarum, Semen Persicae, Fructus Lycii, Cortex Phellodendri, Flos Chrysanthemi, Rhizoma Typhonii, Rhizoma Chuanxiong, Bulbus Lilii, Radix Salviae Miltiorrhizae, Semen Euryales etc. are all more common beauty treatment Chinese medicine.Wherein Radix Angelicae Sinensis is warm in nature, sweet in the mouth, pungent.There is the effect invigorated blood circulation, enrich blood, blood circulation, skin nutrition can be accelerated, make skin health ruddy.Radix Ginseng contains volatile oil, ginsenoside, polysaccharide, multiple low molecular peptide aminoacid, the composition such as vitamin B group, vitamin C, can improve the blood circulation of local skin, strengthen the supply of skin-nourishing material, promote the metabolism of skin, keep the bright and clean and moist of skin, thus the effect of delay skin aging can be played.

Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body are operated, QI-blood circulating regularly freely balances as expensive, if QI and blood is the most smooth will produce blood stasis, blood stasis hinders in internal, will further result in the deterioration of qi-blood circulating, cause more serious stasis of blood plug, therefore the traditional Chinese medical science is with QI and blood as guiding principle, it is allowed to smooth balance by regulating qi and activating blood, can disease-relieving and physique enhancing, beauty treatment of nourishing blood.Skin speckle basic in the stasis of blood, move back speckle must first blood stasis dispelling, blood stasis dispelling when invigorating blood circulation, invigorate blood circulation more must QI invigorating, regulate the flow of vital energy, qi being the governor of blood, blood runs therewith；Blood is keeping of gas, that be so incensed that and quiet, depressed then blood clotting, the deficiency of vital energy then blood prostration, and gas is compeled then blood and walked.QI and blood and then all and.And regulate the flow of vital energy liver, QI invigorating is at lung kidney, lung governing skin and hair.Because of qi depression to blood stasis, have influence on the QI-blood circulation function of lung spleen Liver and kidney, and cause face and the mottles such as chloasma, black eye, eye pouch, eye edema, freckle occur, alopecia, alopecia areata even occur.

Rhizoma Polygonati Odorati also has fertile Rhizoma Polygonati Odorati, and bright Rhizoma Polygonati Odorati, outside tail ginseng grade.This product sweet in the mouth, greasiness, soft and moist edible, it is longer than yin nourishing, mainly act on taste, therefore take not imapirment of the spleen and stomach for a long time, cure mainly the few expectorant of the dry cough caused by deficiency of lung-YIN, pharynx dryness of the tongue and epidemic febrile disease later stage, or because hyperpyrexia consumption impairment of body fluid liquid the diseases such as Tianjin of occurring is few the most thirsty, inappetence, stomach discomfort.This product is mended and oiliness, cold the driest, therefore has " tonification the five internal organs, nourish QI and blood, flat benefit and moisten, hold concurrently except wind heat " merit, have and nourish the calm neural and effect of heart tonifying.It is applicable to cardiopalmus, angina pectoris.Confirming through modern medicine study, Rhizoma Polygonati Odorati also has hypoglycemic activity, also has moist skin, dissipation skin chronic inflammatory disease and treatment to get injured by a fall the effect sprained.

1. the impact on blood pressure: to anesthetized rabbit intravenous injection 20% Rhizoma Polygonati Odorati (Shandong Laoshan product) decoct, every 1,2 or 5ml, all make blood pressure slowly increase.And anesthetized dog dosage (5ml) intravenous injection, blood pressure is without significant change, but larger dose (10ml) intravenous injection can make the of short duration decline of blood pressure.Separately have been reported that, 100% Rhizoma Polygonati Odorati (Yuquan, northeast product) injection, 5% or 10% Rhizoma Polygonati Odorati stem and leaf preserved material, 10% or 100% Rhizoma Polygonati Odorati stem and leaf decoct and 10% Rhizoma Polygonati Odorati root extractum (preparation that Rhizoma Polygonati Odorati subterraneous stem makes), all have of short duration hypotensive effect to anesthetized dog, rabbit.After cutting off both sides vagus nerve or injecting atropine, hypotensive effect weakens.

2. pair action of the heart: 20% Rhizoma Polygonati Odorati (Shandong Laoshan product) decoct or Rhizoma Polygonati Odorati tincture, makes heart contraction strengthen isolated frog heart low dose of (2-5 drips), and amplitude strengthens, and heavy dose of (10) make heartbeat weaken and stop rapidly.Separately having been reported that and show, 100% Rhizoma Polygonati Odorati (Yuquan, northeast product) injection, on isolated frog heart low dose without impact, heavy dose then suppresses；First suppress then to strengthen to the contractility of isolated heart, on heart rate without impact.Rhizoma Polygonati Odorati injection 0.2ml/kg intravenous injection is in rabbit, to cardiac contractile force in place and heart rate all without obvious effect.Rabbit acute myocardial ischemia caused by pituitrin there is certain protective role.The steroid glycoside that Rhizoma Polygonati Odorati contains, the effect to cardiac muscle is similar with Herba Convallariae preparation.Rhizoma Polygonati Odorati glycocide has cardiotonic to isolated frog heart, and the effect of Rhizoma Polygonati Odorati decoct is similar with Rhizoma Polygonati Odorati glycocide.

3. the impact on blood glucose: rabbit, with 0.5g/kg preserved material intramuscular injection, can make blood glucose rise；And its extractum is administered orally, blood glucose is fallen after rising.Adding the sincere report of rattan, induction glycosuria mice is made blood glucose produce significant decline by water portion and the n-butanol fraction of the methanolic extract of Rhizoma Polygonati Odorati the most after 4 hours.Rhizoma Polygonati Odorati methanolic extract has obvious reduction effect to the blood glucose value of epinephrine induced hyperglycemia mice.And show the tendency improving resistance to sugar function.One of its mechanism of action is to inhibit liver glycolysis system.Also having been reported that, the rat blood sugar caused glucose and alloxan with Rhizoma Polygonati Odorati gavage rat raises inhibitory action.

4. the effect of pair blood vessel: frog system vascular and lower limb vascular perfusion experiment result show, 20% Rhizoma Polygonati Odorati (Shandong Laoshan product) decoct, the significant minimizing of blood vessel perfusion flow can be made.Anesthetized dog intravenous injection 20% Rhizoma Polygonati Odorati decoct 10ml, can make kidney volume reduce.Separately have been reported that and show that 100% Rhizoma Polygonati Odorati (Yuquan, northeast product) injection has dilating effect to Bufo siccus lower limb vascular.Isolated rabbit ear vessls experiment shows that 100% Rhizoma Polygonati Odorati injection 0.4ml/kg is injected by tube for transfusion, distends the blood vessels.And retain the in vitro rabbit ear blood vessel that nerve links, by injecting 0.4ml/kg in lateral ear vein, there is not substantially expansion, illustrate that the effect of Rhizoma Polygonati Odorati expansion blood vessel is unrelated with nerve.

5. on blood fat and the impact of the experimental auspicious plaque of tremulous pulse medicated porridge: pharmacology teaching and research group of Jinzhou Medical College reports, 100% Rhizoma Polygonati Odorati decoct is gavaged to experimental cholesterol-fed rabbits, every 5ml, three times a day, totally 30 days, compared with matched group, 10,20,30 days triglyceride, cholesterolemia and B-lipoprotein all have decline upon administration.Rhizoma Polygonati Odorati (Yuquan, northeast product) injection gavages or intramuscular injection every day 2 times, totally 4 rubs root.Result shows, Rhizoma Polygonati Odorati has the effect that prevention triglyceride rises, and cholesterolemia ratio upon administration has substantially increasing before being administered.Therefore think that Rhizoma Polygonati Odorati injection has certain therapeutical effect to hypertriglyceridemia.Formation (perusal) to animal artery atherosclerotic plaque has certain mitigation.

Herba Centellae has a heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect.Deep skin cell can be stimulated to substitute.Herba Centellae can be compacted epidermis and corium coupling part, skin can be made to limber up, contribute to solving cutis laxa phenomenon, make skin smooth flexible；Promoting that in skin corium, collagen protein is formed, and makes fibrin regenerate, reconnect is got up, and makes skin reach smooth effect of compacting.Also assist in impaired organization healing and consolidation skin.Being closely connected between epidermis with corium can be promoted, the increase of adipose cell can be suppressed again, prevent hydroderma, obesity occurs.Herba Centellae is applicable to various skin quality, and the water extract of its plumelet has the effect of anti-inflammation, and it belongs to dicotyledon Umbelliferae, can dispel abscess by subduing swelling and detoxicating.

The Radix Astragali based on qi-restoratives, can invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cave in for insufficiency of vital energy and blood, skin infection, difficulty in discharging of pus or burst for a long time and do not hold back person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration strengthening, the abscess suppuration granulation promoting of disunion i.e. for a long time.Modern medicine study shows, the Radix Astragali includes and multiple antibiotic effective ingredient, and the immunologic function of energy enhancing body, therefore can be used for preventing the generation of some infectious disease." book on Chinese herbal medicine meets former " carries: " all void of Radix Astragali energy tonifying five ZANG-organs, controls stringy pulse spontaneous perspiration, rush down YIN-fire, removes lung-heat, lossless, sends out, and has antiperspirant then to stop." it is to promote resistance and the good medicine of defence disease.

The Radix Paeoniae Alba enters liver, spleen channel, nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing receives antiperspirant.Controlling the chest and abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, and married woman's blood closes obstructed, repercussive blood, can lose pus, benefit woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui, bring down a fever, relieving restlessness, QI invigorating, the hot disease of sky row, and pestilence miasma, mania and irritation, married woman's blood is transported, and hemorrhoidal hamorrhage, rushes down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, skin ulcer scabies, headache, improving eyesight, conjunctival congestion exerts meat.The many QI invigorating of redness of the skin or complexion person, white person controls blood.

Pseudobulbus Bletillae (Rhizoma Bletillae) property is bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.Function cures mainly astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin；Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.Shennong's Herbal: " main carbuncle, malignant boil, lose cellulitis, the dead flesh of impairment of YIN, pathogen in stomach "；Compendium of Material Medica: " abnormal smells from the patient (root) is bitter, flat, nontoxic.

Radix Angelicae Dahuricae meridian distribution of property and flavor: pungent, temperature.Attach to the lung and stomach meridians.Expelling wind and cold, sensible pain relieving, detumescence and apocenosis, dampness leukorrhagia stopping." Japan hanako materia medica ": control conjunctival congestion bulbar conjunctiva polyp, and tire patching leakage landing, broken stagnated blood, mend fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, evacuation of pus, desolation, scabies, pain relieving granulation promoting, go face defect scar.

Radix Salviae Miltiorrhizae is bitter, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc..Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea has good effect." detailed outline " carries: Radix Salviae Miltiorrhizae, and by " the sensible opinion of married woman " cloud, SIWU TANG is controlled gynecopathy, paid no attention to antenatal puerperal, how many through water, and the most generally applicable, only taste Radix Salviae Miltiorrhizae dissipates, and cures mainly same.Lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, and peaceful tire, fall stillborn fetus, only metrorrhagia dysentery, regulating menstruation arteries and veins.Main Compositions of Radix Salviae Miltiorrhizae TANSHINONES has expansion blood vessel, improves the effect such as circulation, releasing intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, beneficially liver cell regeneration.

Flos Inulae, latin name (Calendula officinalis), have another name called Calendula officinalis, asphodel.Calendula officinalis rich in multivitamin, especially vitamin A and vitamin C, pigementation can be prevented, promote skin gloss and elasticity, delaying senility, avoid that skin is lax raw to wrinkle.Also can prevent ciril disease, such as vascular lesion and cancer, more can regulate the flow of vital energy cough-relieving, stomach invigorating, reduce phlegm, prevention of asthma and bronchitis.The most each position can eat；Its petal has the function of beauty treatment, and flower is containing carotenoid, lycopene, violaxanthin, rubixanthin, volatile oil, resin, lymphatic temperament, malic acid etc..Root contains amaroid, mountain gold east glycol；Seed is containing glyceride, ceryl alcohol and alkaloid.Put in shampoo so that hair color is thin out.

Herba Menthae, popular name, " lunar caustic grass ", for labiate, i.e. belongs to other dry herbs together, is born in by hill wetland river more, and rhizome grows wild underground, is a kind of fragrant crop having extraordinary economic worth.Herb green grass or young crops gas fragrance.Leaf, to life, spends little lavender, lip, ties the granule fruit of dark violet brown after spending.Herba Menthae is one of China's conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, the disease such as headache, conjunctival congestion, fever of the body, throat, dental bed swell and ache.Place is with can training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc..Herba Menthae is China's conventional Chinese medicine, and children's tender stem point can make vegetable edible, and herb can be used as medicine again, and curing cold heating laryngalgia, headache, conjunctival congestion with ophthalmalgia, myalgia, the diseases such as skin rubella scratches where it itches, measles without adequate eruption, the most effective to carbuncle, cellulitis, scabies, tinea, dermatitis rhus in addition.Herba Menthae contains menthol, this material can fresh breath there is the multiple property of medicine, stomachache, gallbladder problem such as spasm can be alleviated, also have antisepsis and sterilization, diuresis, reduce phlegm, stomach invigorating and the effect such as aid digestion.A large amount of edible Herba Menthaes may result in insomnia, but low dose of eating conduces to sleep.

Flos Carthami (Classification system: Carthamus tinctorius L.), another name: red blue flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, dry tubular flower, orange red, floral tube is narrow carefully, and tip 5 splits, and sliver is narrow linear, flower pesticide yellow, being unified into pipe, exceed outside sliver, its central authorities have stigma to expose.Have special fragrance, mildly bitter flavor.To spend, length of a film, color be scarlet, the soft person of matter is preferred.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, breast side of body twinge, traumatic injury, skin infection swell and ache curative effect.Blood circulation promoting and blood stasis dispelling, wet dissipation is had to go the effect swollen.

Herba Leonuri acrid in the mouth is bitter, cool, invigorates blood circulation, silt of dispelling, regulating menstruation, disappear water, treats menoxenia, and vaginal bleeding during pregnancy is had difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Herba Leonuri has inducing diuresis to remove edema, shrinks the effect of uterus effect, is that ancient Chinese medicine doctor is for treating gynopathic key medicine.Herba Leonuri can all herbal medicine, effective ingredient is Herba Leonuri element, and Herba Leonuri is containing multiple alkaloid and benzoic acid, the potassium chloride etc. such as leonurine, stachydrine, leonuridine, leonurinine.Motherwort formulation has the effect of excited animal uterus, similar to pituitrin, and Herba Leonuri extractum and decoct have strong and lasting excitation to uterus, not only can strengthen its contractility, can improve its tensity and shrinkage factor simultaneously.

Radix Ampelopsis is the root of vitaceae Radix Ampelopsis, excavates in annual spring, autumn, removes stem and thin fibrous root, and after cleaning, many rip cuttings become two lobes, pintongs or inclined tab, dry and can be used as medicine.It is cool in nature, and bitter but sweet flavor is pungent, has effect of heat clearing away, removing toxic substances, eliminating stagnation, granulation promoting, pain relieving, is used for treating the diseases such as carbuncle, furuncle, scrofula, scald, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula.

Radix Trichosanthis, Chinese medicine name." book on Chinese herbal medicine justice ": medicine what is called Radix Trichosanthis person wantonly, i.e. cuts into slices with it with the root that withers, has the name of powder, real without powder.Radix Trichosanthis is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, and for clearing away heat-fire class medicine, its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, and evacuation of pus is subsided a swelling.Cure mainly: control that calentura is thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For treatment diabetes, conventional it with drugs for nourishing yin with the use of, to reach the effect for the treatment of both the principal and secondary aspects of a disease.

Chinese angelica blood supplementing；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The all cards of main blood deficiency；Menoxenia；Amenorrhea；Dysmenorrhea；Lump in the abdomen knot is poly-；Metrorrhagia；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness of the skin；Dryness of the intestine dyschezia；Weight after bloody dysentery；Ulcer sores；Injury from falling down.Motherland's medical science is thought, Radix Angelicae Sinensis sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, invigorating middle warmer has, has benefit, for the key medicine in blood in row.Thus, it can be enriched blood, and can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example, through the commonly encountered diseases of women such as (during menstrual onset, occurring that mouth and nose are bled), can use angelica for treating.Radix Angelicae Sinensis is that the most frequently used medicine in the traditional Chinese medical science is used for Baoshang, is best to Anemic patients especially.Body hemopoietic function can also be remarkably promoted, raise erythrocyte, leukocyte and content of hemoglobin

Flos Rosae Chinensis flower can extract spice.Root, leaf, spend and all can be used as medicine, there is promoting blood circulation and detumescence, eliminating inflammation and expelling toxin effect.And be gynecological's good medicine simply.The traditional Chinese medical science is thought, Chinese rose sweet in the mouth, warm in nature, and entering Liver Channel has effect of promoting blood flow to regulate menstruation, subduing swelling and detoxicating.Owing to the blood stasis dispelling of Flos Rosae Chinensis, circulation of qi promoting, analgesic effect are obvious, therefore it is commonly used for treating the disease such as menoxenia, dysmenorrhea.Menorrhagia, leucorrhea are many, are decocted in water for oral dose with Flos Rosae Chinensis (or root) 15g or stew Carnis Sus domestica food；Flos Rosae Chinensis 10g, Fructus Jujubae 12g are with decocting, and soup adds proper honey after becoming and takes, and this side is the most fragrant but also sweet, does not seems medicine, the most effective to menopausal hot flashes.Additionally, women commonly uses the soaked tea-drinking of working as of Chinese rose petal, or add Instant Drinks in other JIANMEI CHA, also can functions of improving blood circulation and face-beautifying, make people reside permanently in the youth.

Fructus Broussonetiae this product is the dry mature fruit of moraceae plants Broussonetia papyrifera Broussoneria papyrifera (L.) Vent..Gather during fruit maturation in autumn, clean, dry, remove the membranaceous Constellation calyx of canescence and impurity.Containing Saponin etc..Cold in nature, sweet in the mouth.Function cures mainly: the kidney invigorating liver heat removing, improving eyesight, diuresis.Swoon blurred vision, mesh raw nebula film, edema distension for soreness of the waist and knees, asthenia hectic fever due to YIN-deficiency, sand.Nourishing kidney, liver heat removing, improving eyesight.Control asthenia, blurred vision, corneal nebula, aqueous vapor edema." not Lu ": " main impotence edema, QI invigorating, fill skin, improving eyesight." " Japan hanako materia medica ": " strengthening bone and muscle, aid yang qi, qi-restoratives labor, helps waist knee joint, benefit color.Kidney, qi-restoratives labor, improving eyesight are supported in " " book on Chinese herbal medicine converges and says ": " spleen invigorating.

Flos Rosae Rugosae: road in " book on Chinese herbal medicine text ": " Flos Rosae Rugosae, turbid clearly and not, and and the most violent; easing the affected liver is waken up stomach, and thin gas is invigorated blood circulation, and a surname is logical stops up stagnant and that the most pungent temperature is the driest fraud; disconnected push away among edema caused by disorder of QI medicine, has most a prompt effect and the most tractable, fragrant all product; there is no equal " in Flos Rosae Rugosae containing 300 various chemical components, such as the alcohol of fragrance, aldehyde, fatty acid, phenol and containing the oil of essence and fat, often food Flos Rosae Rugosae goods are waken up stomach with easing the affected liver, have a respite and invigorate blood circulation, looks improving and the skin nourishing, makes us refreshing refreshing.The flower opened at the beginning of Flos Rosae Rugosae and root can be used as medicine, and regulate the flow of vital energy, invigorate blood circulation, Thyme Extract, cure mainly menoxenia, the diseases such as traumatic injury, irritability are had a stomachache, newborn too fat to move pain.The sarcocarp of Rosehips, can be made into fruit jam, has flavour, and fruit contains abundant vitamin C and Citrin, and acute and chronic infectious disease, coronary heart disease, hepatopathy and prevention can be prevented to produce carcinogen etc..With roseleaf with Flos Rosae Rugosae quintessence oil (title Liquor Rosae Rugosae Distillata) obtained by way of distillation refinement, androgen and sperm can be activated.Liquor Rosae Rugosae Distillata can also improve skin texture, blood circulation promoting and metabolism.

Pericarpium Citri Reticulatae, Chinese medicine name.For rutaceae orange Citrus reticulata Blanco and the dry mature skin of variety thereof.Medical material is divided into " Pericarpium Citri Reticulatae " and " Pericarpium citri reticuatae chachiensis ".Harvesting ripe fruit, strips peel, dries or cold drying.Bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm." Mingyi Bielu ": the therapeutic method to keep the adverse QI flowing downwards, preventing or arresting vomiting.Compendium of Material Medica: treat vomit the sound of vomiting regurgitation noisy, time vomiting watery fluid.

Saying Flos Nelumbinis described in Flos Nelumbinis Compendium of Material Medica, Semen Nelumbinis, Testa Nelumbinis, Receptaculum Nelumbinis, Stamen Nelumbinis, Plumula Nelumbinis, Folium Nelumbinis, Petiolus nelumbinis, Nodus Nelumbinis Rhizomatis etc. are the most pharmaceutically acceptable.Flos Nelumbinis energy promoting blood circulation and hemostasis, the pathogenic wind expelling that dries, the removing heat from blood that clears away heart-fire, solution thermal detoxification.Semen Nelumbinis can nourish heart, kidney tonifying, spleen reinforcing, astringing intestine to stop diarrhea.Stamen Nelumbinis can clear away heart-fire, kidney tonifying, arresting seminal emission, hemostasis, expelling summer-heat relieving restlessness, promoting the production of body fluid to quench thirst.Folium Nelumbinis energy clearing away summer-heat and eliminating dampness, yang invigorating stop blooding, weight-reducing, and wherein Folium Nelumbinis letter composition is for cleaning the intestines and stomach, and fat reducing row's stasis of blood has special effect.Nodus Nelumbinis Rhizomatis can stop blooding, dissipating blood stasis, relieving heat toxin.Petiolus nelumbinis energy clearing away summer-heat, ventilation row water, pathogenic fire purging clear away heart-fire.In these, medicine is from same plant, but different position effects differs: Nodus Nelumbinis Rhizomatis hemostasis, dissipating blood stasis；Folium Nelumbinis clearing away summer-heat and eliminating dampness, sending up the lucid YANG, hemostasis；Petiolus nelumbinis clearing away summer-heat, ventilation row summer-heat；Folium Nelumbinis Basis clearing away summer-heat dries and blood is antiabortive；Flos Nelumbinis promoting blood circulation and hemostasis, dry pathogenic wind expelling；Receptaculum Nelumbinis repercussive, stop blooding, dry；Stamen Nelumbinis clears away heart-fire, kidney tonifying, arresting seminal emission, hemostasis；Semen Nelumbinis nourish heart, kidney tonifying, spleen reinforcing, astringing intestine to stop diarrhea, " Hunan lotus seeds " with Hunan are the most famous；Testa Nelumbinis can be held back, be helped and join tonifying spleen-yin；Plumula Nelumbinis clears away heart-fire, reduces phlegm and internal heat, stops blooding, arresting seminal emission.Various in style due to lotus, the different parts of different cultivars, its drug effect may slightly difference.

Semen Lablab Album, a kind of crops, can dry, edible after stir-fry.Semen Lablab Album sweet in the mouth, slightly warm in nature, there are the effects such as invigorating the spleen for eliminating dampness, inducing diuresis to remove edema, liver heat removing and eyesight improving.Semen Lablab Album, another name bean, Semen Vignae Cylindricae, south Seem Lablab Album；Latin literary fame Dolicho, the mature seed of lablabL. annual voluble herb plant Seem Lablab Album, annual voluble herb.Seem Lablab Album originates in the torrid areas such as India, Indonesia, about introduces China between Chinese Shanxi.Autumn, mature fruit of gathering in season in winter two, dry, and takes out seed, then dries.Seed flat ellipse or flat oval, the light Herba Amaranthi tricoloris in surface is white or faint yellow, smooth, slightly gloss, a lateral edges bossed white semilune strophiole.Feeble QI, lightly seasoned, that chews has beany flavor.About the literature record of Semen Lablab Album, see " Mingyi Bielu " that between the Southern Dynasties's neat beam, TAO Hong-Jing writes the earliest.The Compendium of Material Medica that bright Li Shizhen (1518-1593 A.D.) writes is said: " taking duricrust Semen Lablab Album, gross weight fries, and is used as medicine ", and " duricrust Semen Lablab Album, it is sub substantial, and Bai Erwei is yellow, and its gas raw meat is fragrant, and it is warm in nature flat, obtains neutralization, and the paddy of spleen is also.The lunar edema caused by disorder of QI of people, tonneau three is burnt, can change clear the turbid descending, therefore specially control the disease of Middle Palace, relieves summer heat and dehumidifies and detoxify also.Its soft shell and black magpie color person, its slightly cool in nature, but it is available for food, also adjust taste." Pharmacopoeia Commission of the Ministry of Public Health compile " Chinese Pharmacopoeia " also say: " strengthening the spleen and stomach, clearing away summer-heat is wet for Semen Lablab Album.For weakness of the spleen and stomach, diarrhea due to summer heat and dampness, leucorrhea ".In a word, Semen Lablab Album is precious all over the body, and its fruit (Semen Lablab Album), peel (Testa dolichoris), flower, leaf all can people's medicines.Its nature and flavor are sweet micro-wet, enter taste two warp, have tonifying the spleen and stomach, and middle removing dampness, the effect of removing toxic substances of relieving summer heat, cure mainly weakness of the spleen and stomach, have loose bowels, vomit, accumulate in heat-damp in summer, the inferior disease of abdominal distention, red and white leukorrhea, again can alcoholic intoxication.

Flos Albiziae filigree pink, pod is inclined, is urban path tree, views and admires tree.Heartwood Huang taupe, sapwood yellow-white, durable, it is used for furniture processed；Tender leaf is edible, and Lao Ye can do washing clothes；Bark hyoscine, has the effect of anthelmintic.It also has calming effects, mainly controls the effects such as pent-up is uncomfortable in chest, insomnia forgetfulness, nourishing YIN and invigorating YANG, ophthalmic, neurasthenia.Shennong's Herbal: " Herba Albiziae, settling five organs, and will make us happy carefree." " book on Chinese herbal medicine is just read ": " can nourish blood, lively atmosphere, promote blood circulation." " classifying herbal ": " can clear away heart-fire improving eyesight, nourishing kidney-yin.”

Embodiment 1

Xia Qiu plucks Rhizoma Polygonati Odorati, is dried and makes, and steeps and extracts into ethanol, as component 1；

Take Herba Menthae, Pericarpium Citri Reticulatae, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 2；

By remaining raw material Herba Centellae, the Radix Astragali, Herba Leonuri, Semen Lablab Album, Radix Salviae Miltiorrhizae, Pericarpium Citri Reticulatae, Radix Trichosanthis, Flos Carthami, the Radix Paeoniae Alba, Flos Nelumbinis, Radix Ampelopsis, Flos Rosae Chinensis, Flos Inulae, Radix Angelicae Sinensis, Fructus Broussonetiae, Flos Rosae Rugosae, Flos Pelargonii, Flos Albiziae.With ethanol extraction 2 times, merge concentrated extracting solution, as component 3；

Adding substrate propolis with component 3 after component 1, component 2 being mixed to be in harmonious proportion, ultraviolet sterilization tinning, the present invention does not contains preservative, it is necessary to cold preservation.

Embodiment 2:

Rhizoma Polygonati Odorati can be plucked during Xia Qiu, by Rhizoma Polygonati Odorati 3500g chopping good for dry in the sun, cross 100-120 mesh sieve, being equipped with in lid stainless steel cask by the Rhizoma Polygonati Odorati of chopping, add 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, make fully to expand；By bottom percolator filter plate gauze bag parcel pave after again the drug sample after moistening expansion is mixed pine do dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, medicated powder loads 2/3 eminence that must not exceed percolator；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow per minute 2～3ml, filtrate puts into liquid container, and pours ethanol during emptying into liquid container；Percolate is merged and stands.Heating is concentrated into paste, stand for standby use, becomes component 1.Herba Menthae 1000g, Pericarpium Citri Reticulatae 1000g, Radix Angelicae Dahuricae 1000g and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1000g way of distillation are vaporized into crystallization, pulverize stand-by, for component 2；nullAgain by other raw materials Herba Centellae 1000g，Radix Astragali 1000g，Herba Leonuri 1000g，Semen Lablab Album 1000g，Radix Salviae Miltiorrhizae 1000g，Pericarpium Citri Reticulatae 1000g，Radix Trichosanthis 1000g，Flos Carthami 1000g，Radix Paeoniae Alba 1000g，Flos Nelumbinis 1000g，Radix Ampelopsis 1000g，Flos Rosae Chinensis 1000g，Flos Inulae 1000g，Radix Angelicae Sinensis 1000g，Fructus Broussonetiae 1000g，Flos Rosae Rugosae 1000g，Flos Pelargonii 1000g，Flos Albiziae 1000g，Add soak with ethanol 4-6 hour accounting for its quality 5-10 times amount，Heating extraction 2 times，1-2 hour every time，United extraction liquid，Supernatant is removed after standing，Then 100-120 mesh filters，The ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming again，The filtrate of 1.25 when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C，Stand for standby use.Two kinds of filtrates above-mentioned steps extracted, put in economic benefits and social benefits vacuum concentrator and mix, and first concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, then inserts 0～5 DEG C of deepfreeze 24 hours；The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml extractum Han 0.1g, becomes component 3.Component 1 putting into component 3 in component 2, stirs, heating, mediation substrate propolis, ultraviolet sterilization tinning, the present invention does not contains preservative, it is necessary to cold preservation.

Embodiment 3

Can pluck Rhizoma Polygonati Odorati during Xia Qiu, by Rhizoma Polygonati Odorati 4000g immersion water good for dry in the sun 12 hours, be then placed in extraction pot heated and boiled 1 hour, filter, filtrate is standby；Filtering residue adds water, second time heating, boils 45 minutes, filters, and filtrate is standby；Filtering residue adds water, for the third time heated and boiled half an hour, filters；Three filtrates being combined, by filtered through gauze, add 50-60% ethanol in residue, 60 DEG C-70 DEG C are continued extraction 2h, every 10min and stir once, and filtered through gauze merges lixiviating solution, becomes component 1；Herba Menthae 1000g, Pericarpium Citri Reticulatae 1100g, Radix Angelicae Dahuricae 1000g and the Pseudobulbus Bletillae (Rhizoma Bletillae) 1100g way of distillation are vaporized into crystallization, pulverize stand-by, for component 2；Take Herba Centellae 1200g, Radix Astragali 1100g, Herba Leonuri 1100g, Semen Lablab Album 1200g again, Radix Salviae Miltiorrhizae 1200g, Pericarpium Citri Reticulatae 1000g, Radix Trichosanthis 1000g, Flos Carthami 1200g, Radix Paeoniae Alba 1200g, Flos Nelumbinis 1100g, Radix Ampelopsis 1200g, Flos Rosae Chinensis 1100g, Flos Inulae 1100g, Radix Angelicae Sinensis 1100g, Fructus Broussonetiae 1100g, Flos Rosae Rugosae 1200g, Flos Pelargonii 1100g, Flos Albiziae 1100g, be soaked in water, heated and boiled 3 times, 1-2 hour every time, filtering, filtrate is standby；By in the filtrate suction concentrating under reduced pressure tank merging latter 3 times, being evaporated to relative density is 1.20, the extractum of temperature to 60 DEG C-70 DEG C；Become component 3, blending ingredients 1 and component 2 component 3, mediation substrate, become gel；Described substrate is selected from: propolis.Ultraviolet sterilization tinning, the present invention does not contains preservative, it is necessary to cold preservation.

Pharmacological toxicity is tested

Toxicology test:

Test example 1: acute toxicity test of the present invention

One, test material:

Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding.Medicine: cosmetic cream of the present invention.

Two, method:

1, LD50 calculates: use improvement karber's method, mice is randomly divided into 5 groups, often group 10, male and female half and half, dissolve lotion, are made into Cmax, being administered by the maximum allowable capacity of mice, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), after animal fasting (can't help water) 18 hours, it is administered (interval half an hour), each 0.5ml in one day at twice, observes animal dead situation.

2, maximum tolerated dose measures (MTD value): take mice 20, each 10 of male and female.Tablet adds distilled water dissolve, be made into maximum concentration, by the maximum tolerated dose of animal, can twitch with injection filling hello device and be as the criterion.After animal fasting (can't help water) 18 hours, (interval half an hour) it is administered at twice in one day, 0.5ml (every ml 0.36g Han crude drug) every time, total dose is 18g crude drug/kg.d, 300 times of quite clinical adult's 50Kg body weight consumption.Continuous Observation 7 days after administration.

Three, result of the test:

In LD50 calculates when giving mice with maximum acceptable concentration and maximum allowable capacity (18g/Kg.d), have no dead mouse, i.e. do not measure LD50, seek maximum tolerated dose only, in 7 day observation period, its appetite of animal, activity, hair color, the mental status etc. are all normal, grow normal, there are no death.I.e. select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD ＞ 18g/Kg.d.

Test example 2: acute skin irritation test of the present invention is reported

1, experiment purpose: the detection present invention is to the stimulation/corrosiveness of laboratory animal skin and intensity

2, material and method:

2.1. tested material title: cosmetic cream of the present invention (embodiment method 2 prepares)

2.2. laboratory animal: one grade of big ear white race rabbit, 10, female, body weight 2.1-2.3kg；Thered is provided by Affiliated Hospital of Qingdao University biology department Experimental Animal Center；

2.3. test method:

Select the healthy rabbits 10 that skin is intact, its spinal column both sides, back were cut by hair in first 24 hours in test, remove the left and right each about 4cm × 4cm of gross area.Taking tested material 0.2ml during test to be applied on two layers of gauze of 2.5cm × 2.5cm, be applied to skin of unhairing surface, side, oilpaper covers, immobilization with adhesive tape.Opposite side skin is as blank.After closing 4 hours, dismantling, and go to remain tested material with warm water cleaning, position dermoreaction is smeared in the observations in 1,24 and 48 hours after removing tested material, and marks.

3, experimental result: any erythema does not occurs in laboratory animal skin, red and swollen, inflammation phenomenon.

4, brief summary: judging according to skin wound repair standards of grading in " disinfection technology standard " (1999), ointment of the present invention belongs to nonirritant to animal skin stimulus intensity.

Embodiment 3: vaginal mucomembranous irritant test result

1. test method:

After laboratory animal is quarantined 3 days, select 18 above-mentioned healthy rabbits, be randomly divided into three groups, often organize each 6, be respectively as follows: blank, excipient control, eye cream of the present invention.It is placed in excipient control group and tested material treated animal intravaginal with appropriately sized sterilizing cotton sliver leaching with sterile saline and tested material respectively, contacts with vaginal mucosa 6 hours, after 24 hours, put to death animal.Taking-up topical vaginal tissue, observes pathological changes situation.

2, result of the test: vaginal mucomembranous irritant test result

Embodiment 4: skin allergy experimental result

Using cosmetic cream of the present invention, carry out inducing and exciting contact test, viewing test mice behind 24 hours and 48 hours, all loseing skin has the phenomenon such as erythema and edema, with negative control group zero difference.Result shows, this unguentum is bordering on zero to dermoreaction intensity, i.e. without skin allergic reaction.

Embodiment 5: long term toxicity test data

1, experimental technique

Random for Cavia porcellus part is become 4 groups, often group 15.In guinea pig back spinal column both sides, depilatory is uniformly coated with so that it is depilation scope about 40 square centimeters.Clean depilatory, often organize Cavia porcellus after observing 24 hours and be coated with eye cream 0.2,0.4 and 0.8ml of the present invention respectively, respectively containing crude drug 92,184 and 368mg, another group is coated with the every twice-daily of solvent 0.8ml, continuous 30 days, observing the ordinary circumstance of Cavia porcellus, experiment is put to death animal after terminating and is carried out hematology, blood biochemical and pathological examination.

2, result

Above-mentioned three groups of medication Cavia porcellus trunks go to hair-fields, have no that local skin has edema, hyperemia, erythema, petechia and ulcer.Medication group and control animals chroma of hair, ingest, the matched group no significant difference such as extremity are movable, blood biochemistry checking, medication group and matched group are all in normal range.Histopathologic examination, tests each group of heart, liver, kidney and local skin and is showed no obvious pathological changes.Prompting, Chinese medicine facial cream long-term prescription of the present invention is showed no obvious toxic action to local skin and whole body important organ.

Pharmacological experiment

One, the microcirculation experimental technique of the present invention:

1, materials and methods: take 50 mices, is randomly divided into 5 groups, often 10 (male and female half and half) of group, and it is a little that matched group every Mus auris dextra is coated with normal saline；Positive controls every Mus auris dextra gives commercially available L'Oreal the multiple crease-resistant moist late frost 15ml that compacts of face, and tested group is external beauty cream 15ml of the present invention.15min pneumoretroperitoneum injects 0.1% pentobarbital sodium 0.1ml/10g anesthetized animal, tail vein injection 0.1% epinephrine 0.1mL/10g subsequently, observes mouse right ear fine motion vein bore (μm) immediately and 0.2mm2 blood capillary net number .t inspection processes experimental data.

2 results and discussion

2.1. on microcirculatory impact

Compared with matched group, tested group 1 has showed increased (P ＜ 0.01) to mice capillary open number；Tested group 2 venule bore and capillary open number are dramatically increased (P ＜ 0.01)；Mice fine motion, vein bore and capillary open number all had increase (P ＜ 0.01) by tested group 3；Illustrate to be improved microcirculation by reagent, have function of promoting blood circulation to disperse blood clots (table 1).

Table 1, beauty cream of the present invention are on mice fine motion, vein bore and the impact of capillary open number

Two, the impact on Oleum Tiglii induced mice auricle edema

Take healthy mice 30, it is randomly divided into 3 groups, i.e. blank group, the multiple crease-resistant moist late frost positive controls of compacting of face of commercially available L'Oreal, beauty cream of the present invention, often group 10, male and female half and half, positive controls and instant component are not smeared, blank group smears isodose normal saline, successive administration 7 days, it is administered latter 0.5 hour in last, survey outside the left in ear of mice and be coated with Oleum Tiglii proinflammatory agent (2% Oleum Tiglii, 20% dehydrated alcohol, 5% distilled water, 73% ether) 0.1ml causes inflammation, cause inflammation and lay a left side with card punch (aperture 6mm) in latter 4 hours, auris dextra sheet, weigh, using left and right auricle weight difference as swelling degree, the results are shown in Table 2.

The table 2 impact (X ± SD) on Oleum Tiglii induced mice auricle edema

Note: compare with matched group: * * P ＜ 0.01；Compare with positive controls: #P ＜ 0.05；By upper table experimental result it can be seen that eye cream of the present invention has pharmacological action of preferably subsiding a swelling.

Three. the impact of rat paw edema caused by Carrageenan

Take healthy rat 30, body weight 180-220g, be randomly divided into blank group, multiple crease-resistant moist late frost positive controls, the beauty cream of the present invention of compacting of face of L'Oreal.Often group 10, male and female half and half, sub-cage rearing.Positive controls and drug component of the present invention smear 0.2g other every day, blank group gives the normal saline of same dosage and smears, successive administration 7 days, it is administered latter 30 minutes in last, inflammation is only caused respectively at Rat Right metapedes plantar subcutaneous injection 1% carrageenin suspension 0.1ml/, and within 15,30,60,120,240 minutes, survey the girth of the Rat Right metapedes sole of the foot before causing inflammation after cause inflammation, and calculate swelling rate [swelling rate=(causing the scorching front foot sole of the foot girth of inflammation metapedes sole of the foot girth-cause) scorching front foot sole of the foot girth × 100% of/cause]；The results are shown in Table 3.

The impact (X ± SD) of rat paw edema caused by table 3 Carrageenan

Note: compare with matched group: * * P ＜ 0.01；Compare with positive controls: #P ＜ 0.05；By upper table experimental result it can be seen that medicine group of the present invention has more preferable crease-resistant flat muscle, eliminate the pharmacological action of skin pattern.

3 discuss

Clinical trial

Illustrate: my institute, in JIUYUE, 2014 in JIUYUE ,-2015, uses self-control anti-wrinkle cream, to facial wrinkles, Neck wrinkles, canthus wrinkle, and evident in efficacy, existing report is as follows.

Clinical data: clinic chooses facial wrinkles, canthus wrinkle, Neck wrinkles obvious person 100 example.All women.Age 35-55 year, average 42 years old；Unmarried 20 example, the married 80 example, do not educate person 77 example；The course of disease 6 months-20 years, average 9.58 years；Educational level University Culture 67 people, white collar, teacher, cadre, office staff 65 example, other staff 22 example.Readme often stay up late overtime work 43 examples, heredity 35 fall, 20 examples of having a sleepless night, daily maintenance skin person 78 people, laser therapy wrinkle removal 26 people.Clinic is divided into treatment group 50 example, matched group 50 example.

Therapeutic Method: treatment group uses homemade traditional Chinese drug beauty cream, Fang Yong: Rhizoma Polygonati Odorati 30g, Herba Centellae 12g, Radix Astragali 13g, Herba Leonuri 12g, Semen Lablab Album 12g, Radix Salviae Miltiorrhizae 12g, Pericarpium Citri Reticulatae 13g, Radix Trichosanthis 12g, Flos Carthami 11g, Radix Paeoniae Alba 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 13g, Herba Menthae 13g, Flos Nelumbinis 12g, Radix Ampelopsis 12g, Radix Angelicae Dahuricae 12g, Flos Rosae Chinensis 12g, Flos Inulae 13g, Radix Angelicae Sinensis 12g, Fructus Broussonetiae 11g, Flos Rosae Rugosae 11g, Flos Pelargonii 11g, Flos Albiziae 12g.It is fabricated to facial cream as described in Example 2.

Take matched group, often organize 50 examples, use the multiple crease-resistant moist late frost that compacts of face of commercially available L'Oreal respectively.

Operating process: when carrying out in the flat bed of personnel, with 3% hydrogen peroxide cleaning face, with negative ion atomizer spraying face, coordinate meridian point massage 12 methods to carry out facial massage simultaneously, emphasis massage is done in local near the eyes, takes late frost, be uniformly applied to face after time about 10min., it is careful not to do into eyes, can suitably massage 10-15 minute.Once a day, 15 days courses for the treatment of.After the course for the treatment of terminates, monthly follow up a case by regular visits to 1 time, follow up a case by regular visits to continuously 3 months.Advise patient to eat less during treatment pungent, take a good rest, and disable other beauty care items.

Criterion of therapeutical effect

Effect is obvious: after treating for 2 courses for the treatment of, facial skin is compacted, face wrinkles, and chin compacts, canthus wrinkle is substantially desalinated, and curative effect maintains more than 1 month, and facial skin is slightly improved and compacted, corners of the mouth wrinkle, and chin wrinkle improves, and eyestrain is alleviated；Effective: eye pouch, canthus wrinkle are the most thin out, disappear more than 50%, the conscious satisfaction of patient, sleep quality is good；Or eye pouch disappears during treatment, but it is bad to follow up a case by regular visits to middle sleep, and overtime work has again recurrence；Invalid: chin, corners of the mouth wrinkle change inconspicuous or unchanged without significant change, eye pouch, canthus wrinkle；Or once disappeared more than 50%, but substantially increase the weight of in following up a case by regular visits to, testing crew is unsatisfied with.

Therapeutic outcome: treatment group total effective rate compares with each matched group, difference all has significance (P ＜ 0.01), illustrates that making beauty cream curative effect by oneself is substantially better than the commercially available anti-wrinkle product that compacts.Refer to table 1

13 groups of Comparison of therapeutic tables (%) of table

Note: compare * P ＜ 0.01 with other each group

Follow-up results follows up a case by regular visits to find, massage person is better than the personage not massaged.Adhere to that using effect is obvious.Herba Centellae has a heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect.Deep skin cell can be stimulated to substitute.Rhizoma Polygonati Odorati is mended and oiliness, cold the driest, therefore has " tonification the five internal organs, nourish QI and blood, flat benefit and moisten, hold concurrently except wind heat " merit, have and nourish the calm neural and effect of heart tonifying.It is applicable to cardiopalmus, angina pectoris.Confirming through modern medicine study, Rhizoma Polygonati Odorati also has hypoglycemic activity, also has moist skin, dissipation skin chronic inflammatory disease and treatment to get injured by a fall the effect sprained.

The invention discloses a kind of Chinese medicine anti-wrinkle composition, be made up of Chinese medicinal ingredients.Wherein, Radix Angelicae Sinensis promotes skin metabolism, skin lightening of invigorating blood circulation；The Radix Angelicae Dahuricae, Poria, Semen Armeniacae Amarum whitening and moistening skin；Pseudobulbus Bletillae (Rhizoma Bletillae) consolidation smoothing wrinkle；Flos Rosae Chinensis has whitening convergence granulation promoting, promotes cell regeneration and effect of cicatrix healing, is the treasure of whitening and skin-protecting；Herba Centellae energy aging resistance, consolidation pore, effect except microgroove, be also the anti-ageing holy product of beauty treatment.There is effect that skin lightening of invigorating blood circulation, whitening are wrinkle resistant, it is adaptable to person in middle and old age, the skin that aging is lax, wrinkle gathers.

Claims (10)

1. a Traditional Chinese Medicine Anti drawn grain frost manufacture method, it is characterised in that comprise the following steps:

A. the making of Rhizoma Polygonati Odorati, extraction, as component 1；

B. take Herba Menthae, Pericarpium Citri Reticulatae, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, As component 2；

C. by remaining crude drug ethanol extraction 2 times, concentrated extracting solution is merged, as component 3；

D. add substrate propolis with component 3 after component 1, component 2 being mixed to be in harmonious proportion, cold preservation after sterilization tinning.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 1, it is characterised in that described step In a, take the Rhizoma Polygonati Odorati chopping will plucked autumn in summer, cross 80-100 mesh sieve.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 1, it is characterised in that described step In a, farther include the step of extraction, the Rhizoma Polygonati Odorati of chopping has been placed in lid stainless steel cask, has added 70% second Alcohol liquid, quality is 0.8-1 times of coarse powder, stirs, moistening airtight placement more than 1 hour, makes fully Expand；Again the drug sample after moistening expansion is mixed after bottom percolator, filter plate gauze bag parcel is paved Pine does to dissipate, and then contains powder with rustless steel spoon, loads percolator uniformly, fills 10-12 cm thick, with T-shaped Rod pressure is even, then presses aforesaid operations, and loading in layer is suitably pressurizeed, and medicated powder loads must not exceed and oozes Filter 2/3 eminence of cylinder；Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and Put a container, be then slowly added into 70% ethanol；Air between medicated powder powder to be discharged, and have second Alcohol flows out about about 20L, closes baiting valve, covers cylinder of filtering, dipping 24 hours, then opens baiting valve and enter Row percolation, controls percolation speed and is generally 1000g medical material outflow per minute 2～3ml, and filtrate puts into reservoir In cylinder, and pour ethanol during emptying into liquid container；Being merged by percolate and stand, heating is concentrated into cream Shape, stand for standby use, become component 1.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 1, it is characterised in that described step In b, take Herba Menthae, Pericarpium Citri Reticulatae, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation and be vaporized into crystallization, pulverized 120-150 mesh thin Sieve stand-by, as component 2.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 1, it is characterised in that described step In c, remaining raw material described is added soak with ethanol 4-6 hour accounting for its quality 5-10 times amount, heating extraction 2 Secondary, each 1-2 hour, united extraction liquid, remove supernatant after standing, then 100-120 mesh filters, then The ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming, ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C Time 1.25 filtrate, stand put in economic benefits and social benefits vacuum concentrator mix, first concentrate the filtrate to 80 DEG C of phases It is the concentrated solution of 1.32 to density, then inserts 0～5 DEG C of deepfreeze 24 hours；Cold preservation liquid is added 0.3% Filter aid kieselguhr, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g Extractum, as component 3.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 1, it is characterised in that described step In d, three kinds of component mixing that above-mentioned steps is extracted, stir, heating, mediation substrate, substrate Select propolis, ultraviolet sterilization bottling cold preservation.

7. a Traditional Chinese Medicine Anti drawn grain frost, it is characterised in that described crease-resistant facial cream includes following weight portion Number crude drug: Rhizoma Polygonati Odorati 10～50 parts, Herba Centellae 10～20 parts, the Radix Astragali 10～20 parts, Herba Leonuri 10～ 20 parts, Semen Lablab Album 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Pericarpium Citri Reticulatae 10～20 parts, Radix Trichosanthis 10～20 parts, Flos Carthami 10～20 parts, the Radix Paeoniae Alba 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～20 parts, Flos Nelumbinis 10～20 Part, Radix Ampelopsis 10～20 parts, the Radix Angelicae Dahuricae 10～20 parts, Flos Rosae Chinensis 10～20 parts, Flos Inulae 10～20 parts, when Return 10～20 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～15 parts, Flos Pelargonii 10～15 parts, Flos Albiziae 10～15 parts.

Traditional Chinese Medicine Anti drawn grain frost the most according to claim 7, it is characterised in that wrap in described crease-resistant facial cream Include the crude drug of following parts by weight: Rhizoma Polygonati Odorati 10～30 parts, Herba Centellae 10～15 parts, the Radix Astragali 10～15 parts, Herba Leonuri 10～15 parts, Semen Lablab Album 10～15 parts, Radix Salviae Miltiorrhizae 10～15 parts, Pericarpium Citri Reticulatae 10～15 parts, Radix Trichosanthis 10～15 parts, Flos Carthami 10～15 parts, the Radix Paeoniae Alba 10～15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～15 parts, Herba Menthae 10～20 parts, Flos Nelumbinis 10～20 parts, Radix Ampelopsis 10～20 parts, the Radix Angelicae Dahuricae 10～20 parts, Flos Rosae Chinensis 10～20 parts, Flos Inulae 10～ 20 parts, Radix Angelicae Sinensis 10～20 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～15 parts, Flos Pelargonii 10～15 parts, Flos Albiziae 10～15 parts.

Traditional Chinese Medicine Anti drawn grain frost manufacture method the most according to claim 7, it is characterised in that described crease-resistant Facial cream includes the crude drug of following parts by weight: Rhizoma Polygonati Odorati 10～40 parts, Herba Centellae 10～20 parts, the Radix Astragali 10～20 parts, Herba Leonuri 10～20 parts, Semen Lablab Album 10～20 parts, Radix Salviae Miltiorrhizae 10～20 parts, Pericarpium Citri Reticulatae 10～20 Part, Radix Trichosanthis 10～20 parts, Flos Carthami 10～20 parts, the Radix Paeoniae Alba 10～20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 parts, Herba Menthae 10～15 parts, Flos Nelumbinis 10～15 parts, Radix Ampelopsis 10～15 parts, the Radix Angelicae Dahuricae 10～15 parts, Flos Rosae Chinensis 10～15 parts, Flos Inulae 10～15 parts, Radix Angelicae Sinensis 10～15 parts, Fructus Broussonetiae 10～20 parts, Flos Rosae Rugosae 10～15 parts, India Certain herbaceous plants with big flowers 10～15 parts, Flos Albiziae 10～15 parts.

10. according to the using method of Traditional Chinese Medicine Anti drawn grain frost, its feature according to any one of claim 7～9 Being, this anti-wrinkle paste does not contains preservative, it is necessary to cold preservation, the most just before going to bed after face cleaning, by anti-wrinkling cream Uniform application is in face, and by middle finger finger belly at face message 15-20 minute, after fully absorbing to it, Getting up early in two days washes away.