CN105616317A - Herba centellae eye cream capable of relieving eye wrinkles and eye bags and preparation method for eye cream - Google Patents

Abstract

The invention provides herba centellae eye cream capable of relieving eye wrinkles and eye bags. The eye cream comprises the following raw herbs in parts by weight: 10-50 parts of herba centellae, 10-20 parts of rhizoma typhonii, 10-20 parts of radix angelicae sinensis, 10-20 parts of white poria, 10-20 parts of radix notoginseng, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of peach kernels, 10-20 parts of radix ginseng, 10-20 parts of rhizoma ligustici chuanxiong, 10-20 parts of radix paeoniae rubra, 10-20 parts of bletilla striata, 10-20 parts of white muscardine silkworm, 10-20 parts of rhizoma corydalis, 10-20 parts of caulis spatholobi, 10-20 parts of radix angelicae, 10-20 parts of rhizoma cyperi, 10-20 parts of calendula officinalis, 10-20 parts of radix polygonati officinalis, 10-20 parts of pelargonium, 10-20 parts of flores chamomillae, 10-20 parts of euphrasia pectinata and 10-20 parts of syringa oblatavar alba. According to the eye cream, ancient and modern traditional Chinese medicine pharmacological research achievements are referred and natural traditional Chinese medicines capable of tonifying vital energy, activating blood, clearing liver, improving vision, nourishing liver and kidney, removing nebula, calming liver, suppressing yang, clearing heat and toxins, relieving swelling and removing water are screened, so that the eye cream has the effects of straightening healthy energy to eliminate evils and relaxing bowels to remove toxins.

Description

A kind of Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch and preparation method thereof

Technical field

The present invention relates to containing the beauty treatment preparation deriving from plant, animal or mineral component, particularly to a kind of Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch and preparation method thereof.

Background technology

Chinese medicine beauty treatment is under the guidance of Chinese medicine rationale, by using beauty treatment oral medicinal herb or the outer a kind of method being used for recovering or improve the physiological function of body. Interior oral administration, from internal benefiting vital QI and blood, adjustment function, makes people's QI and blood abundant, radiant. Outer usage be use medicine directly act on body surface local, it utilizes the performance of medicine, make QI and blood flowing, unimpeded through gas, with reach beauty treatment health care effect. Compared with chemical toilet, Chinese medicine beauty treatment has outstanding feature and advantage. One is that Chinese medicine beauty treatment combines together with Chinese medicine, has significantly functional, and its principle is the same with Chinese medicine, focuses on overall conditioning, emphasizes first to nurse one's health inherence, then will shape in outward, therefore, cosmetic result persistently, stable. Two is with theory of Chinese medical science for instructing, and has theory of Chinese medical science feature, such as organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, property theory, compound compatibility, has the thinking different from modern cosmetics. Three is have pure natural property, Chinese medicine in cosmetic sunscreen relatively synthetic there is uniqueness and significant advantage, there is the features such as nontoxic, harmless, not carcinogenic.

It is too fat to move that eye pouch refers to that lower eyelid portion organizes, and takes the shape of a bag and hangs from above. In frame, fat content and the supportive structure of lower eyelid maintain poised state under normal circumstances, when this balance changes owing to capsula adiposa bulbi accumulation is too much or lower eyelid support structure thin is weak, capsula adiposa bulbi is broken through the restriction of lower eyelid and is protruded from outside socket of the eye, namely forms the bag-shaped deformity of lower eyelid. Clinical manifestation is that skin of lower eyelid is lax, piles up, capsula adiposa bulbi is deviate to hang from above and is taken the shape of a bag, outer canthus position moves down, lower margo palpebrae is not tight with eyeball laminating, lower margo palpebrae radian increases, moving the tear that overflows outside lower lacrimal point, the aging absorption of facial skeleton causes that lower eyelid support structure secondary relaxes, and is the main cause of person in middle and old age's eye pouch formation.

Eye pouch is caused due to cutis laxa. This understanding has very big representativeness. Through demonstration, it also it is the main cause of eye pouch generation. So, lifting skin tightness is main improvement approach. More satisfactory mode is oral collagen. But do not extravagantly hope and thoroughly improve at short notice, because the reparation of eye pouch is to need certain process.

Increasing the weight of of eye pouch is owing to hyperliposis causes. This is also great representational understanding, and Orbital septum fat has its normal physiological function, and its major function is protection eyeball. Also it is one of reason forming eye pouch simultaneously. Why form " pouch sample " outward appearance, entirely due to caused by the hypotonia of socket of the eye barrier film. The minimizing technology of this eye pouch is just by operation liposuction. If after operation liposuction, and not carrying out the reparation of socket of the eye barrier film, consequence inevitably results in eye pouch recurrence. If taking out fat in a large number, that necessarily causes the depression of lower eyelid, increases the weight of aged appearance.

Cosmetics can rescue eye pouch. This to analyze from two aspects, if " functional " eye pouch, say, that during eye pouch substantially, time and inconspicuous. Suitable applied nutrition frost class cosmetics for prevent eye pouch increase the weight of can play a role. And once eye pouch is " pathologic ", namely organizational structure there occurs change, and eye pouch manifests for a long time, and increases the weight of gradually. If one want to cosmetics are corrected, that is entirely futile effort. Eyes maintenance must be carried out in advance, the outer physiologic factor of the few pathologic factor of eye pouch depolarization accounts for the overwhelming majority, a large amount of women ignore the demand to eyes maintenance when health, and after causing starting aging occurs, speed is very fast, and conscious before aging to carry out maintenance extremely important.

Occurring and increasing the weight of of eye pouch is one of old and feeble mark of skin of face. Want the generation avoiding eye pouch completely, be unrealistic be also impossible. Because aging is the natural law, it is overpowering. But as long as noting a little, it it is the generation being entirely possible to and delaying and prevent eye pouch.

Cause eye pouch and have six reasons

1, spleen and stomach function weakens, and can cause internal hydrops, causes palpebra inferior to relax, forms eye pouch.

2, liver is one of toxin expelling and hemopoietic system, liver opening at eye, and the problem of liver shows eyes place entirely, if liver cannot clear toxin, will form eye pouch.

3, suffer from a deficiency of the kidney body fluid metabolic obstacle can occur, deficiency of kidney-QI, with the passing of time cause that QI and blood is smooth, eye pouch occurs.

4, from the science of channels and collaterals, palpebra inferior walks stomach warp, and the position of eye pouch is Tongzi point and the SIBAI point place of stomach warp. There is decline in body fluid metabolic function, stomach function is deteriorated, and makes Tongzi point and SIBAI point block and causes.

5, the blood circulation of circumference of eyes easily becomes because of overwork to be retarded by silt, and blood vessel refluxes not smooth owing to silting up, causes lymph metabolism to slow down, makes unnecessary moisture and accumulation of blood below eyes, then form eye pouch.

6, skin hydropenia is serious, and each cell of skin is required for enough nutrients, when skin does not have enough hydrones for a long time to prop up, also results in the lax of skin change, causes that eye pouch occurs or increases the weight of.

Herba Centellae, for perennial draft of crawling. Another name: 18 lack, collapse jorum, Herba Calthae Membranaceae, Gotu Kola, Carnis Arca inflata shell grass, Hydrocotyle vulgaris L., tiger grass, Herba sambuci chinensis etc. Be born in by dark and damp wasteland, village, roadside, limit, ditch. Stem is thrown oneself on the ground, and joint is taken root. Leaf alternate, petiole is long; Blade circle or kidney shape, diameter 2��4 centimetres. Clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating. Controlling eruptive disease stomachache, diarrhea due to summer-heat, dysentery, jaundice due to damp-heat, sand Stranguria, stranguria with blood, tell, be defeated in battle, hemoptysis, conjunctival congestion, larynx swells, rubella, scabies, furuncle carbuncle poison, traumatic injury.

Pharmacological action: to maincenter effects on neural system

Mice, rat are had calmness, stable effect by glycoside contained therein, and this effect is mainly the impact on the cholinergic system in central nervous system. Alcohol extract is without analgesic activity.

Effect to skin histology

Asiaticoside can treat skin ulcer, such as intractable wound, tuberculosis of skin, leprosy etc. To mice, Cavia porcellus, rabbit muscle are injected or are subcutaneously implanted and can promote skin growth, the Acceleration of growth etc. of local leukocytosis, connective tissue coil pipe net hypertrophy, mucous secretion increase, hair and tail. Once had report with containing Herba Centellae 0.25��1% alcohol extract (containing asiatic acid, Asiaticoside) cream (wherein still containing embryo's or calf, pig or Corii Caprae seu Ovis skin, liver, brain water-alcohol extraction) treat dermatosis, obtain good result.

Beautification function

Herba Centellae has a heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect. Deep skin cell can be stimulated to substitute. Herba Centellae can be compacted epidermis and corium coupling part, skin can be made to limber up, contribute to solving cutis laxa phenomenon, make skin smooth flexible; Promoting that in skin corium, collagen protein is formed, and makes fibrin regenerate, reconnect is got up, and makes skin reach smooth effect of compacting. Also assist in impaired organization healing and consolidation skin. Being closely connected between epidermis with corium can be promoted, the increase of adipose cell can be suppressed again, it is prevented that hydroderma, appearance obesity.

Herba Centellae is applicable to various skin quality, and the water extract of its plumelet has the effect of anti-inflammation, and it belongs to dicotyledon Umbelliferae, and energy subduing swelling and detoxicating is dispelled abscess.

Eye pouch can pass through operative correction. Laser also can improve eye pouch, promotes the metabolism of skin, promotes the circulation of blood, lymph circulation, makes the desalination slowly of deep eye pouch, and about course for the treatment of just can be appreciated that obvious laser beautifying goes the effect of eye pouch later. Laser goes eye pouch to be belonging to noinvasive beauty treatment, need not anaesthetize, laser goes the phenomenon that eye pouch other can have local red and swollen after administering the treatment, this belongs to normal phenomenon, the nursing of circumference of eyes and daily maintenance if worked good, effect can be more lasting, but expensive, and have certain risk, be not everyone can bear rise.

Summary of the invention

The technical problem to be solved is in that, always going of age, and skin is lax inevitable, and canthus wrinkle, eye pouch slowly climbs up face. And along with the growth at age, spleen and stomach function weakens, internal hydrops can be caused, cause palpebra inferior to relax, form eye pouch; Liver opening at eye, the problem of liver shows eyes place entirely, if liver cannot clear toxin, will form eye pouch; Suffer from a deficiency of the kidney and body fluid metabolic obstacle can occur, deficiency of kidney-QI, with the passing of time cause that QI and blood is not smooth, eye pouch occurs. Though clinical laser has certain curative effect, but expensive, there is side effect in various degree or cause some complication; Chinese medicine product then because of its draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor. But existing prescription specific aim is poor, it is impossible to fundamentally alleviate eye wrinkle-removing, eye pouch, and also have certain side effect. Therefore, the Chinese medicine eye cream finding a kind of highly effective and safe becomes the urgent needs of people.

For solving these technical barriers, the invention provides a kind of alleviation eye wrinkle-removing, the Herba Centellae eye cream of eye pouch, its described Herba Centellae eye cream includes the crude drug of following parts by weight: Herba Centellae 10��50 parts, Rhizoma Typhonii 10��20 parts, Radix Angelicae Sinensis 10��20 parts, Poria 10��20 parts, Radix Notoginseng 10��20 parts, Radix Salviae Miltiorrhizae 10��20 parts, 10��20 parts of Semen Persicae, Radix Ginseng 10��20 parts, Rhizoma Chuanxiong 10��20 parts, Radix Paeoniae Rubra 10��20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��20 parts, Bombyx Batryticatus 10��20 parts, Rhizoma Corydalis 10��20 parts, Caulis Spatholobi 10��20 parts, the Radix Angelicae Dahuricae 10��20 parts, Rhizoma Cyperi 10��20 parts, Flos Inulae 10��20 parts, Rhizoma Polygonati Odorati 10��20 parts, Flos Pelargonii 10��20 parts, Flos Matricariae chamomillae 10��20 parts, Herba Euphrasiae Regelii 10��20 parts, Faeces Passeris 10��20 parts.

Described alleviation eye wrinkle-removing, the Herba Centellae eye cream of eye pouch, its described Herba Centellae eye cream can include the crude drug of following parts by weight: Herba Centellae 10��40 parts, Rhizoma Typhonii 10��15 parts, Radix Angelicae Sinensis 10��15 parts, Poria 10��15 parts, Radix Notoginseng 10��15 parts, Radix Salviae Miltiorrhizae 10��15 parts, 10��15 parts of Semen Persicae, Radix Ginseng 10��15 parts, Rhizoma Chuanxiong 10��15 parts, Radix Paeoniae Rubra 10��15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��15 parts, Bombyx Batryticatus 10��20 parts, Rhizoma Corydalis 10��20 parts, Caulis Spatholobi 10��20 parts, the Radix Angelicae Dahuricae 10��20 parts, Rhizoma Cyperi 10��20 parts, Flos Inulae 10��20 parts, Rhizoma Polygonati Odorati 10��20 parts, Flos Pelargonii 10��20 parts, Flos Matricariae chamomillae 10��20 parts, Herba Euphrasiae Regelii 10��20 parts, Faeces Passeris 10��20 parts. .

Described alleviation eye wrinkle-removing, the Herba Centellae eye cream of eye pouch, its described Herba Centellae eye cream can also include the crude drug of following parts by weight: Herba Centellae 10��50 parts, Rhizoma Typhonii 10��20 parts, Radix Angelicae Sinensis 10��20 parts, Poria 10��20 parts, Radix Notoginseng 10��20 parts, Radix Salviae Miltiorrhizae 10��20 parts, 10��20 parts of Semen Persicae, Radix Ginseng 10��20 parts, Rhizoma Chuanxiong 10��20 parts, Radix Paeoniae Rubra 10��20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��20 parts, Bombyx Batryticatus 10��15 parts, Rhizoma Corydalis 10��15 parts, Caulis Spatholobi 10��15 parts, the Radix Angelicae Dahuricae 10��15 parts, Rhizoma Cyperi 10��15 parts, Flos Inulae 10��15 parts, Rhizoma Polygonati Odorati 10��15 parts, Flos Pelargonii 10��15 parts, Flos Matricariae chamomillae 10��15 parts, Herba Euphrasiae Regelii 10��15 parts, Faeces Passeris 10��15 parts.

For solving above-mentioned technical problem, the preparation method that the present invention also provides for a kind of Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch, its described preparation method comprises the following steps:

A. the preparation of Herba Centellae, extracts, as component 1;

B. take Radix Notoginseng, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the Rhizoma Cyperi way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 2;

C. by all the other crude drug soak with ethanol, extract, as component 3;

D., component 1, component 2 adding after mixing with component 3 Cera Flava be in harmonious proportion, sterilize tinning.

In described step a, it is possible to take the Herba Centellae chopping will plucked spring and summer, cross 80-100 mesh sieve.

In described step a, it is possible to farther including the step extracted, be placed in by medicated powder in lid stainless steel cask, added 70% ethanol, quality is 0.8-1 times of coarse powder, stirs, moistening airtight placement more than 1 hour, make abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 1.

In described step b, take Radix Notoginseng, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the Rhizoma Cyperi way of distillation and be vaporized into crystallization, pulverized 120-150 order dusting cover stand-by, as component 2.

In described step c, it is possible to all the other raw materials described being cut into coarse powder, has been placed in by medicated powder in lid stainless steel cask, add 70% ethanol, quality is 0.8-1 times of coarse powder, stirs, moistening airtight placement more than 1 hour, make abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 3.

In described step d, it is possible to blending ingredients 1, component 2 stir with component 3, add Cera Flava eye cream, and ultraviolet sterilization is bottled.

For solving above-mentioned technical problem, the present invention also provides for the using method of a kind of Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch, its usage is, after each face cleaning just before going to bed, by eye cream uniform application near the eyes, and massaging near the eyes 15-20 minute by middle finger finger belly, after fully absorbing to it, getting up early in second day washes away.

The present invention is with reference to the achievement of Chinese medicine pharmacological research at all times, the natural Chinese medicine that screening inrigorating qi and promoting blood circulation, liver heat removing and eyesight improving, nourishing liver and kidney, improving acuity of vision and removing nebula, suppressing the hyperactive liver and subsiding YANG, heat-clearing and toxic substances removing, detumescence dewater, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, regulate the metabolism function of human body, improve human body periocualr skin blood circulation, thus reaching detumescence blood stasis dispelling, fatigue alleviating, eye skin of compacting. Desalination eye pouch, beautifies the purpose of appearance. The present invention, according to Traditional Chinese medical theory and modern pharmacological research result, repeated screening medicine for external use, is configured to Chinese medicine eye cream, has blood circulation promoting and blood stasis dispelling, improving acuity of vision and removing nebula, temperature promoting blood circulation, and skin-active is subsided a swelling, blood-nourishing and freckle-removing, the effect of the skin that compacts. Can effectively expand peripheral vessel, improve face microcirculation near the eyes, blood stasis dispelling of subsiding a swelling, pigmentation is had certain inhibitory action. Therapeutic effect of the present invention is more satisfactory, and non-toxic and safe, and preparation method is simple and easy to do, can create good social benefit and economic benefit.

Detailed description of the invention

Cosmetics can rescue eye pouch. This to analyze from two aspects, if " functional " eye pouch, say, that during eye pouch substantially, time and inconspicuous. Suitable applied nutrition frost class cosmetics for prevent eye pouch increase the weight of can play a role. And once eye pouch is " pathologic ", namely organizational structure there occurs change, and eye pouch manifests for a long time, and increases the weight of gradually. If one want to cosmetics are corrected, that is entirely futile effort. Eyes maintenance must be carried out in advance, the outer physiologic factor of the few pathologic factor of eye pouch depolarization accounts for the overwhelming majority, a large amount of women ignore the demand to eyes maintenance when health, and after causing starting aging occurs, speed is very fast, and conscious before aging to carry out maintenance extremely important. Its outstanding maintenance can usefulness be formed frivolous such as the moistening sebum film of yarn at skin surface, produces remarkable moistening effect, keeps skin youth moistening.

Theory of Chinese medical science thinks major part eye pouch, eye edema, and the generation of edema is relevant with Liver and kidney void, after Liver and kidney void, kidney essense can not nourishing the liver blood, and " liver opening at eye ", finally because essence and blood loses, show and eyes be formed for eye pouch and eye edema. And modern study also confirms that eye pouch, eye edema is owing to often staying up late, emotional instability, eye strain, aging, cause that vein blood vessel blood flow rate is excessively slow, and eye part skin red blood cell is for hypoxgia, in vein blood vessel, carbon dioxide and metabolic waste accumulation are too much, forming chronic hypoxia, blood is dark and forms delay and causes eye pouch, and this matches with theory of Chinese medical science.

Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body are operated, QI-blood circulating regularly freely balances as expensive, if QI and blood is not smooth will produce blood stasis, blood stasis hinders in internal, will further result in the deterioration of qi-blood circulating, cause more serious stasis of blood plug, therefore the traditional Chinese medical science is with QI and blood for guiding principle, by regulating qi and activating blood so as to smoothness balances, can disease-relieving and physique enhancing, beauty treatment of nourishing blood. Skin speckle basic in the stasis of blood, move back speckle must first blood stasis dispelling, blood stasis dispelling when invigorating blood circulation, invigorate blood circulation more must QI invigorating, regulate the flow of vital energy, qi being the governor of blood, blood runs therewith; Blood is keeping of gas, that be so incensed that and quiet, depressed then blood clotting, the deficiency of vital energy then blood prostration, and gas is compeled then blood and walked. QI and blood and then all and. And regulate the flow of vital energy liver, QI invigorating is at lung kidney, lung governing skin and hair. Because of qi depression to blood stasis, have influence on the QI-blood circulation function of lung spleen Liver and kidney, and cause face and occur alopecia, alopecia areata even occurring the mottles such as chloasma, black eye, eye pouch, eye edema, freckle. The present invention mainly identifies and corrects the principle treated according to Chinese medicine, the many doctor chiefs of collection, extensively adopts the strange medicine wonderful recipe in rich receipts area, skims the cream off milk; Choose inrigorating qi and promoting blood circulation, natural Chinese medicine that liver heat removing and eyesight improving, nourishing liver and kidney, improving acuity of vision and removing nebula, suppressing the hyperactive liver and subsiding YANG, heat-clearing and toxic substances removing, detumescence dewater, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, regulate the metabolism function of human body, improve human body periocualr skin blood circulation, thus reaching detumescence blood stasis dispelling, fatigue alleviating, eye skin of compacting. Desalination eye pouch, beautifies the purpose of appearance.

Herba Centellae, for perennial draft of crawling. Another name: 18 lack, collapse jorum, Herba Calthae Membranaceae, Gotu Kola, Carnis Arca inflata shell grass, Hydrocotyle vulgaris L., tiger grass, Herba sambuci chinensis etc. Be born in by dark and damp wasteland, village, roadside, limit, ditch. Stem is thrown oneself on the ground, and joint is taken root. Leaf alternate, petiole is long; Blade circle or kidney shape, diameter 2��4 centimetres. Clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating. Controlling eruptive disease stomachache, diarrhea due to summer-heat, dysentery, jaundice due to damp-heat, sand Stranguria, stranguria with blood, tell, be defeated in battle, hemoptysis, conjunctival congestion, larynx swells, rubella, scabies, furuncle carbuncle poison, traumatic injury.

Pharmacological action: to maincenter effects on neural system

Mice, rat are had calmness, stable effect by glycoside contained therein, and this effect is mainly the impact on the cholinergic system in central nervous system. Alcohol extract is without analgesic activity.

Effect to skin histology

Asiaticoside can treat skin ulcer, such as intractable wound, tuberculosis of skin, leprosy etc. To mice, Cavia porcellus, rabbit muscle are injected or are subcutaneously implanted and can promote skin growth, the Acceleration of growth etc. of local leukocytosis, connective tissue coil pipe net hypertrophy, mucous secretion increase, hair and tail. Once had report with containing Herba Centellae 0.25��1% alcohol extract (containing asiatic acid, Asiaticoside) cream (wherein still containing embryo's or calf, pig or Corii Caprae seu Ovis skin, liver, brain water-alcohol extraction) treat dermatosis, obtain good result.

Beautification function

Herba Centellae has a heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect. Deep skin cell can be stimulated to substitute. Herba Centellae can be compacted epidermis and corium coupling part, skin can be made to limber up, contribute to solving cutis laxa phenomenon, make skin smooth flexible; Promoting that in skin corium, collagen protein is formed, and makes fibrin regenerate, reconnect is got up, and makes skin reach smooth effect of compacting. Also assist in impaired organization healing and consolidation skin. Being closely connected between epidermis with corium can be promoted, the increase of adipose cell can be suppressed again, it is prevented that hydroderma, appearance obesity.

Herba Centellae is applicable to various skin quality, and the water extract of its plumelet has the effect of anti-inflammation, and it belongs to dicotyledon Umbelliferae, and energy subduing swelling and detoxicating is dispelled abscess.

Poria: Poria sweet in the mouth, light, property are put down, and are used as medicine and have the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming. Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect. Poria slightly sweet flavor is put down, and enters the heart, lung, spleen channel. There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming. Dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis can be controlled, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade. The diuretic of Poria, is reached by strong activating the spleen pulmonary function, different from the Chinese medicine of other direct diuretic. For diarrhea due to hypofunction of the spleen, leukorrhagia Poria can spleen invigorating, again can eliminating dampness by diuresis, for having loose bowels caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation, leukorrhagia, application Poria has the effect of giving consideration to both the incidental and fundamental, often and the compatibility such as Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae. Can be used as tonifying the lung spleen, control the adjuvant of the deficiency of vital energy

Flos Pelargonii stops blooding, vasoconstrictive, asthma, liver and expelling toxin, cholelithiasis, kidney toxin expelling, renal calculus, diuresis, muscular soreness, oily skin, aging skin activates, herpes, palor, fat-reducing, promotes to scab, eczema, sunburn of burning, tinea, menstruation has some setbacks, engorgement of breasts inflammation, alleviates melancholy uneasy, drives demon, mend body, deodorization, antibacterial, sterilization, give up smoking (wine). the major function of Flos Pelargonii is in that to adjust skin, and the effective ingredient in Flos Pelargonii extracting solution and natural alicyclic organic have very strong affinity, and therefore, Flos Pelargonii is often combined with alicyclic organic and makes lipoid product. general cleaning supplies are after cleaned, the functional components major part of skin protection can be flush with water loss, the scientific research personnel of Switzerland is on the basis of three-hypers fresh extractor technology, select to hands sections such as organized enzymes by adding, the effective ingredient making Flos Pelargonii also produces affinity with skin epidermal area while affine with lipoid, this affinity has surmounted the affinity with water, therefore, in the process cleaned, most of effective ingredient of Flos Pelargonii still is able to be absorbed by the skin, play the effect adjusting skin, Flos Pelargonii is almost suitable for various skin, because it can balance sebum secretion and make turgor. be likely to eczema, burn, herpes zoster, herpes, tinea and chilblain useful. slack and undisciplined, pore is blocked and oily skin is also fine, due to Flos Pelargonii can pore refining, blood circulation promoting, can allow after using pale skin is comparatively ruddy vigor, make the glossy exquisiteness of skin.

Pseudobulbus Bletillae (Rhizoma Bletillae) property is bitter, sweet, puckery, is slightly cold. Return lung, liver, stomach warp. Function cures mainly astringing to arrest bleeding, detumescence and promoting granulation. Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage. Shennong's Herbal: " main carbuncle, malignant boil, lose cellulitis, the dead flesh of impairment of YIN, pathogen in stomach "; Compendium of Material Medica: " abnormal smells from the patient (root) is bitter, flat, nontoxic.

Radix Angelicae Dahuricae meridian distribution of property and flavor: pungent, temperature. Attach to the lung and stomach meridians. Expelling wind and cold, sensible pain relieving, detumescence and apocenosis, dampness leukorrhagia stopping. " Japan hanako materia medica ": control conjunctival congestion bulbar conjunctiva polyp and tire patching leakage landing, broken stagnated blood, mend fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, evacuation of pus, desolation, scabies, pain relieving granulation promoting, go face defect scar.

Radix Salviae Miltiorrhizae is bitter, is slightly cold. GUIXIN, Liver Channel. Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness. For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia. For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc. Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea has good effect. " detailed outline " carries: Radix Salviae Miltiorrhizae, and by " the sensible opinion of married woman " cloud, SIWU TANG controls gynecopathy, pays no attention to antenatal puerperal, how many through water, and all generally applicable, only taste Radix Salviae Miltiorrhizae dissipates, and cures mainly same. Lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, peaceful tire, and fall stillborn fetus, only metrorrhagia dysentery, regulating menstruation arteries and veins. Main Compositions of Radix Salviae Miltiorrhizae TANSHINONES has expansion blood vessel, improves circulation, releases the effects such as intravascular coagulation, has effect of invigorating blood circulation trace, and can promote that liver blood circulates, is beneficial to liver cell regeneration.

Flos Inulae, latin name (Calendulaofficinalis), have another name called Calendula officinalis, asphodel. Calendula officinalis rich in multivitamin, especially vitamin A and vitamin C, pigementation can be prevented, promote skin gloss and elasticity, delaying senility, avoid that skin is lax raw to wrinkle. Also can prevent ciril disease, such as vascular lesion and cancer, more can regulate the flow of vital energy cough-relieving, stomach invigorating, reduce phlegm, prevention of asthma and bronchitis. Almost each position can eat; Its petal has the function of beauty treatment, and flower is containing carotenoid, lycopene, violaxanthin, rubixanthin, volatile oil, resin, lymphatic temperament, malic acid etc. Root is containing amaroid, mountain gold east glycol; Seed is containing glyceride, ceryl alcohol and alkaloid. Putting into can so that hair color be thin out in shampoo.

Flos Carthami (Classification system: CarthamustinctoriusL.), another name: red blue flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, dry tubular flower, orange red, floral tube is narrow carefully, and tip 5 splits, and sliver is narrow linear, flower pesticide yellow, being unified into pipe, exceed outside sliver, its central authorities have stigma to expose. Have special fragrance, mildly bitter flavor. To spend, length of a film, color be scarlet, the soft person of matter is preferred. Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, breast side of body twinge, traumatic injury, skin infection swell and ache curative effect. Blood circulation promoting and blood stasis dispelling, wet dissipation is had to go the effect swollen.

Semen Persicae (SemenPersicae), can refer to the core youngster in Semen Persicae; When using as Chinese herbal medicine Semen Persicae, refer in particular to the seed of rosaceous plant Fructus Persicae or Prunus davidiana, another name Radix Fici Hirtae core, almond core, big Semen Persicae, pluck during fruit maturation in 6��July, remove sarcocarp and nucleocapsid, take out seed, dry, there is effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, can be used for amenorrhea, dysmenorrhea, abdominal mass mass in the abdomen, injury from falling down, dryness of the intestine constipation etc. Anemia of pregnant woman is cautious use of. Clinical observation proves, blood flow is blocked by Semen Persicae, blood obstacle has improvement result, and each internal organs can be made respectively to organize functional recovery normal.

Spica Prunellae can relieve inflammation or internal heat improving eyesight, can control the effect such as conjunctival congestion and swelling pain, headache. It is liver heat removing, hepatoprotective " panacea ". Specially control order pearl nyctalgia, the vertigo. Purging liver-fire, improving eyesight, mass dissipating and swelling eliminating. For conjunctival congestion and swelling pain, order pearl nyctalgia, dizziness of having a headache, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.

Radix Notoginseng is to be used as medicine with its root, and it is warm in nature, acrid in the mouth, has significant blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain effect, has the good reputation of " Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) ", " southern part of the country SHENCAO ". Excavate in season in winter in spring two because being everlasting, be divided into again " spring seven " and " winter seven ". Qing Dynasty's pharmaceutical texts supplementary Amplifications of the Compendium of Materia Medica is recorded: " ginseng qi-tonifying first, Radix Notoginseng enriches blood first, taste with and merit also etc., therefore claim Panax pseudoginseng, for the most precious person in Chinese medicine. " become famous Chinese patent medicine " YUNNAN BAIYAO " at home and abroad and " Pien Tze Huang ", namely make with Radix Notoginseng for primary raw material. Cure mainly spitting of blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.

The pungent micro-hardship of Rhizoma Cyperi is sweet, flat. Regulate the flow of vital energy resolving depression; Menstruction regulating and pain relieving; Antiabortive. Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement. For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.

The superfine product of " king of BAICAO " " YIN nourishing is mended raw, strengthening the body resistance " is described as by Radix Ginseng from ancient times, containing multiple Saponin and polysaccharide composition, leachate can slowly be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promote cutaneous circulation, increase skin-nourishing, the water and oil balance of regulation of skin, it is prevented that skin dehydration, hardening, wrinkling, Radix Ginseng active substance suppresses melanic reducing property, make skin pure white smooth, skin elasticity can be strengthened, make cell obtain new life, be the superfine product improved looks. Radix Ginseng is directly immersed in 50% glycerol, and after 10 days, face rubbed with the hands by glycerol, or Radix Ginseng is decocted into extract, and every day toward face washing water a bit, rubs face or Radix Ginseng water face-washing with the hands, skin can be allowed quite moist with the glycerol containing Radix Ginseng.

Rhizoma Polygonati Odorati, formal name used at school: Polygonatumodoratum (Mill.) Druce, for Liliaceae herbaceos perennial. Rhizome horizontal walk, meat yellow-white, close raw most fibrous roots. Rhizoma Polygonati Odorati is extracted flavonoid substances and is combined a kind of novel substance of formation-wash pancreas sugar plain (cics) clearly with Folium Mori extract deoxynojirimycin, has blood sugar lowering, blood fat, blood pressure etc. and acts on. Rhizoma Polygonati Odorati tool yin nourishing, moisturize, heat clearing away, promote the production of body fluid, the effect such as cough-relieving. As tonic, cure mainly the diseases such as consumption of YIN caused by febrile disease, deficiency-heat cough caused by dryness, heart disease, diabetes, tuberculosis, and high-grade nourishing food, delicacies and beverage can be made, with health role.

Bombyx Batryticatus is pungent salty, flat. Enter liver, lung, stomach warp. Function cures mainly expelling wind to relieve convulsion, dissipating phlegm and resolving masses. Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble. Sore throat, scrofula tuberculosis. " herbal classic ": main pediatric epilepsy scared night cry, goes three worms, goes out black, and man's the moon infections is sick. " not Lu ": woman's metrorrhagia is red in vain, puerperal remaining pain, all skin ulcer cicatrixs of going out. " detailed outline ": dissipating wind-phlegm tuberculosis, scrofula, wind syndrome of head, wind worm toothache, skin wind skin ulcer, erysipelas is had an itch, intermittent fever due to phlegm crux, married woman's galactostasis, metrorrhagia hematochezia, children's's infantile malnutrition erosion squama body, all incised wounds, furuncle swells wind hemorrhoid.

Rhizoma Corydalis (CorydalisyanhusuoW.T.WangexZ.Y.SuetC.Y.Wu), has another name called: Rhizoma Corydalis, corydalis tuber, rhizoma corydalis, Rhizoma Corydalis etc. For promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis, traumatic injury etc. Pungent; Bitter; Temperature; Nontoxic. Gui Jing: liver; Stomach; The heart; Lung; Spleen channel. Cure mainly: invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving. Main trusted subordinate's all pains of waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury. " Japan hanako materia medica ": except wind, controls gas, warm waist knee joint, and broken disease addiction flutters damage blood stasis, and fall tire, and sudden and violent lumbago. " Kaibao Bencao ": main removing blood stasis, puerperal all diseases, because of the blood person of doing. Married woman's menoxenia, lumps in abdomen, and metrorrhagia drenches dew, and puerperal, blood was transported, and sudden and violent blood rushes to, and because damaging hematochezia, or wine rubs and boils clothes. " Bencao Jingshu ": Rhizoma Corydalis, Wen Zeneng is with smooth, and smooth then gas row; Xin Zeneng moistens and wanders away, and then blood of wandering away is lived. Blood lively atmosphere row, thus can main removing blood stasis and puerperal all cause of disease blood persons of doing. The why uncomfortable person of married woman's menstruation, without he, disharmony between QI and blood, thus stagnate, then can not with up to, and the card in many later stages is also. Abdomen lumps, puerperal blood faints, sudden and violent blood rushes to, because damaging the card such as hematochezia, all must QI and blood and then healing, therefore know lead also. Metrorrhagia drench dew, profit keep unfavorable walk, this is non-use same with the medicine that fills blood then, and having no it can.

Caulis Spatholobi chicken sedan-chair rattan bitter but slightly sweet taste, warm in nature, return liver, the heart, kidney channel; Red complexion enters blood, and matter profit row dissipates; There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation; Cure mainly rheumatic arthralgia, numb hand and foot, quadriplegia, menoxenia, blockage of menstruation, dysmenorrhea, amenorrhea, leukopenia. The treatment waist gonalgia caused by rheumatism, rheumatic arthralgia, numb limbs and tense tendons, often and the compatibility such as Flos Carthami Semen Persicae, Radix Paeoniae Rubra, Pheretima, the Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae. Can be used for menoxenia, amenorrhea, dysmenorrhea, normal and Rhizoma Cyperi, the same use of Herba Leonuri.

The dry tuber of Rhizoma Typhonii TyphoniumgiganteumEngl.. Having the expectorant that dispels the wind, arresting convulsion is jerked, detoxicating and resolving stagnation of pathogens, effect of pain relieving. Stopping up for middle wind-phlegm, mouth eye is sung tiltedly, dysphasia, infantile convulsion epilepsy, tetanus, and syncope due to accumulation of phlegm is had a headache, migraine and general headache, scrofula sucutaneous nodule, venom.

Flos Matricariae chamomillae is feverfew, originates in Europe. Classification system chamomilia Flos Matricariae chamomillae, Anthemis nobilis and Matricaria recutita have many common features: about 30 centimeters high, center yellow, petal white, slightly brushy blade. Chamomile essential oil is also popular health protection and pharmaceutical preparation. Effect of the helpful sleep of Flos Matricariae chamomillae, alleviates inflammation and the pain symptom of patient, alleviates the insomnia caused by neurotic skin pruritus. Also there is a large amount of cultivation in China, in order to be used as medicine and tea making. The effect of Flos Matricariae chamomillae and effect: mildly bitter flavor, Gan Xiang, improving eyesight, move back liver-fire, treatment insomnia, reduces blood pressure, can invigorate, refresh oneself. Memory reinforcing, reduction cholesterol. Expelling phlegm for arresting cough, can effectively alleviate bronchitis and asthma, the myalgia that can releive headache, migraine or flu cause, and centering and gastric acid, calm nerves are helpful. The myalgia that flu is caused can be eliminated, can calm spirit, slow emotion of relaxing, promote sleep quality, also can improve the skin of allergy. Helpful sleep, moist skin, prolonged constipation can be controlled, can eliminate anxiety, eyestrain, lung moistening, health preserving, and the dyspepsia that anxiety causes with anxiety can be treated, and to having a sleepless night, neuralgia and menstrual pain, gastroenteritis all benefits to some extent, alleviates headache. Flu also is had good effect by Flos Matricariae chamomillae tea hot drink! When collutory can alleviate toothache; Add in shampoo and can increase beautiful gloss for hair; Loosen the body and mind of uneasiness, drink in insomnia or the normal evening sending out nightmare, can have beyond thought help! It can also alleviate eyestrain, and the cold tea bag brewed is applied eyes, more can help to remove black eye.

Herba Euphrasiae Regelii formal name used at school: EuphrasiapectinataTen, for annual herb plant, herb tool medical value. Bitter in the mouth; Cold nature. Returning bladder warp, function cures mainly: heat-clearing and toxic substances removing; Diuresis. Main calentura is thirsty; Headache; Cough due to lung-heat; Laryngopharynx swelling and pain; Pyretic stranguria; Dysuria; Aphtha; Carbuncle.

Radix Paeoniae Rubra, Chinese medicine name. Dry root for ranunculaceae plant Radix Paeoniae Rubra or river Radix Paeoniae Rubra. Spring, season in autumn two excavate, and remove rhizome, fibrous root and silt, dry. Hardship, is slightly cold. Return Liver Channel. There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling. For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection. Radix Paeoniae Rubra (parched): after stir-fry, the property of medicine relatively relaxes, promoting blood circulation and stopping pain and not damaging the spleen and stomach, can be used for the stagnant pain of the stasis of blood. Wine Radix Paeoniae Rubra: winning with promoting blood circulation to remove blood stasis power, clearing away heat and cooling blood effect is more weak. It is used for amenorrhea or dysmenorrhea, traumatic injury.

Radix Angelicae Sinensis is sweet, pungent, warm returns liver, the heart, spleen channel. Function cures mainly enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation. The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Weight after bloody dysentery; Ulcer sores; Injury from falling down.

Faeces Passeris, Chinese medicine name. Feces for ploceidae animal Passeris montani saturati Passermontanus (L.). It is distributed in China several throughout whole level land. There is removing food stagnancy, effect of improving eyesight. Being usually used in gathering, hernia, corneal nebula, carbuncle furuncle, tonsillitis are controlled in external. Bitter in the mouth, warm in nature. Return liver, kidney channel removing food stagnancy, improving eyesight.

Specific embodiment 1

Spring and summer plucks Herba Centellae, dry preparation, steeps into alcohol extraction, as component 1;

Take Radix Notoginseng, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae and the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 2;

By all the other raw material Rhizoma Typhoniis, Radix Angelicae Sinensis, Poria, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Ginseng, Radix Paeoniae Rubra, Bombyx Batryticatus, Rhizoma Corydalis, Caulis Spatholobi, Flos Inulae, Rhizoma Polygonati Odorati, Flos Pelargonii, Flos Matricariae chamomillae, Herba Euphrasiae Regelii, Faeces Passeris, with ethanol extraction 2 times or extraction, merge concentrated extracting solution, as component 3;

Component 1, component 2 after mixing with component 3, are added Cera Flava and stir, ultraviolet sterilization tinning.

Specific embodiment 2

Herba Centellae can be plucked during spring and summer, by Herba Centellae 5000g chopping good for dry in the sun, cross 100-120 mesh sieve, being equipped with by medicated powder in lid stainless steel cask, add 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, make abundant expansion, drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder, medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol, air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into, percolate is merged and stands. heating is concentrated into paste, stand for standby use, becomes component 1. Radix Notoginseng 1500g, Rhizoma Chuanxiong 1500g, Radix Angelicae Dahuricae 1500g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 1500g way of distillation are vaporized into crystallization, pulverize stand-by, for component 2, again by Rhizoma Typhonii 1500g, Radix Angelicae Sinensis 1500g, Poria 1500g, Radix Salviae Miltiorrhizae 1500g, Semen Persicae 1500g, Radix Ginseng 1500g, Radix Paeoniae Rubra 1500g, Bombyx Batryticatus 1500g, Rhizoma Corydalis 1500g, Caulis Spatholobi 1500g, Flos Inulae 1500g, Rhizoma Polygonati Odorati 1500g, Flos Pelargonii 1500g, Flos Matricariae chamomillae 1500g, Herba Euphrasiae Regelii 1500g, Faeces Passeris 1500g, by soak with ethanol 24 hours, heating and refluxing extraction 2 times, each 1��2 hour, 2 extracting solution are merged and stands, the filtrate of 1.25 when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, mix two kinds of extraction filtrates and insert in economic benefits and social benefits vacuum concentrator, being concentrated into relative density when 90 DEG C is the concentrated solution of 1.05, set to 0��5 DEG C of deepfreezes 24 hours, the filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g crude drug amount, becomes component 3. component 1 and component 2, component 3 are merged, mediation substrate propolis, become gel, bottle with ultraviolet disinfection.

Specific embodiment 3

Herba Centellae can be plucked during spring and summer, by Herba Centellae 3500g chopping good for dry in the sun, cross 100-120 mesh sieve, being equipped with by medicated powder in lid stainless steel cask, add 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, make abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 1. Radix Notoginseng 1100g, Rhizoma Chuanxiong 1000g, Radix Angelicae Dahuricae 1100g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 1100g way of distillation are vaporized into crystallization, pulverize stand-by, for component 2; Again by Rhizoma Typhonii 1100g, Radix Angelicae Sinensis 1000g, Poria 1000g, Radix Salviae Miltiorrhizae 1100g, Semen Persicae 1200g, Radix Ginseng 1100g, Radix Paeoniae Rubra 1200g, Bombyx Batryticatus 1000g, Rhizoma Corydalis 1000g, Caulis Spatholobi 1000g, Flos Inulae 1000g, Rhizoma Polygonati Odorati 1100g, Flos Pelargonii 1100g, Flos Matricariae chamomillae 1100g, Herba Euphrasiae Regelii 1100g, Faeces Passeris 1100g shred, and cross 100-120 mesh sieve, medicated powder is equipped with in lid stainless steel cask, adding 70% ethanol, quality is 0.8-1 times of coarse powder, stirs, moistening airtight placement more than 1 hour, makes abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 3. Component 1 and component 2, component 3 are merged, mediation substrate propolis, become gel, bottle with ultraviolet disinfection.

Pharmacological toxicity is tested

Acute toxicity testing data

1, experimental technique

Depilatory is uniformly coated with by guinea pig back spinal column both sides, makes unhairing scope about 40 square centimeters. Clean depilatory returns cage to observe 24 hours, often group Cavia porcellus is coated with Chinese medicine eye mask 0.2,0.4 of the present invention and 0.8ml respectively, respectively containing crude drug 92mg, 184mg and 368mg), another group is coated with the every twice-daily of solvent 0.8ml, continuous one week, after experiment terminates, Cavia porcellus is put to death, the heart, liver, kidney and depilation skin do pathological examination.

2, result

Above-mentioned three groups of medication Cavia porcellus trunks depilation district, having no local skin has edema, hyperemia, erythema, petechia and ulcer. Medication group Cavia porcellus chroma of hair, ingest, the matched group no significant difference such as extremity are movable, histopathologic examination, the administration group heart, liver, kidney and depilation skin compare also no significant difference with compareing word.

Result is pointed out, and Chinese medicine eye mask of the present invention, without local irritant effect, also has no general toxicity performance. Show that Chinese medicine eye mask of the present invention uses safety.

Long term toxicity test data

1, experimental technique

Random for Cavia porcellus part is become 4 groups, often group 15. In guinea pig back spinal column both sides, depilatory is uniformly coated with so that it is depilation scope about 40 square centimeters. Clean depilatory, often organize Cavia porcellus after observing 24 hours and be coated with eye mask 0.2,0.4 of the present invention and 0.8ml respectively, respectively containing crude drug 92,184 and 368mg), another group is coated with the every twice-daily of solvent 0.8ml, continuous 30 days, observing the ordinary circumstance of Cavia porcellus, experiment is put to death animal after terminating and is carried out hematology, blood biochemical and pathological examination.

2, result

Above-mentioned three groups of medication Cavia porcellus trunk unhairing districts, having no local skin has edema, hyperemia, erythema, petechia and ulcer. Medication group and control animals chroma of hair, ingest, the matched group no significant difference such as extremity are movable, blood biochemistry checking, medication group and matched group are all in normal range. Histopathologic examination, tests each group of heart, liver, kidney and local skin and is showed no obvious pathological changes. Prompting, local skin and whole body important organ are showed no obvious toxic action by Chinese medicine eye mask long-term prescription of the present invention. Result of the test shows: Chinese medicine eye mask experiment safety of the present invention.

Pharmacological experiment

One, the microcirculation experimental technique of the present invention:

1, materials and methods: take 50 mices, be randomly divided into 5 groups, often 10 (male and female half and half) of group, it is a little that matched group every Mus auris dextra is coated with normal saline; Positive controls every Mus auris dextra gives commercially available herborist new seven supercilious looks frost (Shanghai herborist cosmetics company limited product), and test component is external eye cream 400mg/kg/h of the present invention. 15min pneumoretroperitoneum injects 0.1% pentobarbital sodium 0.1ml/10g anesthetized animal, tail vein injection 0.1% epinephrine 0.1mL/10g subsequently, observes mouse right ear fine motion vein bore (��m) immediately and 0.2mm2 blood capillary net number .t inspection processes experimental data.

2 results and discussion

2.1. on microcirculatory impact

Compared with matched group, mice capillary open number is had showed increased (P < 0.01) by tested group 1; Tested group 2 venule bore and capillary open number are dramatically increased (P < 0.01); Mice fine motion, vein bore and capillary open number all had increase (P < 0.01) by tested group 3; Illustrate to be subject to reagent can improve microcirculation, have function of promoting blood circulation to disperse blood clots (table 1).

The impact on mice fine motion, vein bore and capillary open number of table 1, eye mask of the present invention

Two, the impact on Oleum Tiglii induced mice auricle edema

Take healthy mice 30, it is randomly divided into 3 groups, i.e. blank group, new seven supercilious look frost positive controls, eye cream group of the present invention, often group 10, male and female half and half, positive controls and instant component are not smeared, blank group smears isodose normal saline, successive administration 7 days, it is administered latter 0.5 hour in last, survey outside the left in ear of mice and be coated with Oleum Tiglii proinflammatory agent (2% Oleum Tiglii, 20% dehydrated alcohol, 5% distilled water, 73% ether) 0.1ml causes inflammation, cause inflammation and lay a left side with card punch (aperture 6mm) in latter 4 hours, auris dextra sheet, weigh, using left and right auricle weight difference as swelling degree, result is in Table 2.

The table 2 impact (X �� SD) on Oleum Tiglii induced mice auricle edema

Group	Number of animals (only)	Swelling (mg)
			Blank group	10	8.51��1.72
New seven supercilious look frost groups	10	5.64��1.59**
			Eye cream group of the present invention	10	4.12��1.36#

Note: compare with matched group: * * P < 0.01; Compare with positive controls: #P < 0.05; By upper table experimental result it can be seen that eye cream of the present invention has pharmacological action of better subsiding a swelling.

Three. the impact of rat paw edema caused by Carrageenan

Take healthy rat 30, body weight 180-220g, be randomly divided into blank group, new seven supercilious look frost positive controls, eye cream group of the present invention. Often group 10, male and female half and half, sub-cage rearing. Positive controls and drug component of the present invention smear 0.2g other every day, blank group gives the normal saline of same dosage and smears, successive administration 7 days, it is administered latter 30 minutes in last, inflammation is only caused respectively at Rat Right metapedes plantar subcutaneous injection 1% carrageenin suspension 0.1ml/, before causing inflammation and cause the girth that 15,30,60,120,240 minutes survey the Rat Right metapedes sole of the foot after inflammation, and calculate swelling rate [swelling rate=(cause scorching metapedes sole of the foot girth-cause scorching front foot sole of the foot girth)/cause scorching front foot sole of the foot girth �� 100%]; Result is in Table 3.

The impact (X �� SD) of rat paw edema caused by table 3 on Carrageenan

Note: compare with matched group: * * P < 0.01; Compare with positive controls: #P < 0.05; By upper table experimental result it can be seen that medicine group of the present invention has the pharmacological action of blood stasis dispelling of better subsiding a swelling.

3 discuss

Theory of Chinese medical science thinks major part eye pouch, and the generation of eye edema is relevant with Liver and kidney void, after Liver and kidney void, kidney essense can not nourishing the liver blood, and " liver opening at eye ", finally because of essence and blood loss, show and eyes be formed for lower eyelid edema, eye pouch is very big. And modern study also confirms that eye pouch is owing to often staying up late, emotional instability, eye strain, aging, cause that vein blood vessel blood flow rate is excessively slow, eye part skin red blood cell is for hypoxgia, and in vein blood vessel, carbon dioxide and metabolic waste accumulation too much, form chronic hypoxia, blood is dark and forms the appearance being detained and causing eye eye pouch, eye edema, and this matches with theory of Chinese medical science.

Eye pouch is caused due to cutis laxa. This understanding has very big representativeness. Through demonstration, it also it is the main cause of eye pouch generation. So, lifting skin tightness is main improvement approach. More satisfactory mode is oral collagen. But do not extravagantly hope and thoroughly improve at short notice, because the reparation of eye pouch is to need certain process.

Cosmetics can rescue eye pouch. This to analyze from two aspects, if " functional " eye pouch, say, that during eye pouch substantially, time and inconspicuous. Suitable applied nutrition frost class cosmetics for prevent eye pouch increase the weight of can play a role. And once eye pouch is " pathologic ", namely organizational structure there occurs change, and eye pouch manifests for a long time, and increases the weight of gradually. If one want to cosmetics are corrected, that is entirely futile effort. Eyes maintenance must be carried out in advance, the outer physiologic factor of the few pathologic factor of eye pouch depolarization accounts for the overwhelming majority, a large amount of women ignore the demand to eyes maintenance when health, and after causing starting aging occurs, speed is very fast, and conscious before aging to carry out maintenance extremely important.

Eye pouch should be suited the remedy to the case after being formed, and consults a physician, finds out the cause of disease, treats in time; Keeping in high spirits, reduce mental burden, live a regular life, control tobacco and wine, ensure sufficient sleep, promote QI and blood vigorous, appearance is shone; Strengthen the massage of eye, improve local blood circulation state, reduce congestion and be detained; As being coated with oil-containing and dividing, eye cream that moisture is sufficient, make eye part skin and subcutaneous tissue dynamic, desalinate eye pouch, ocular edema.

The present invention is with reference to the achievement of Chinese medicine pharmacological research at all times, the natural Chinese medicine that screening inrigorating qi and promoting blood circulation, liver heat removing and eyesight improving, nourishing liver and kidney, improving acuity of vision and removing nebula, suppressing the hyperactive liver and subsiding YANG, heat-clearing and toxic substances removing, detumescence dewater, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, regulate the metabolism function of human body, improve human body periocualr skin blood circulation, thus reaching detumescence blood stasis dispelling, fatigue alleviating, eye skin of compacting. Desalination eye pouch, beautifies the purpose of appearance. The present invention, according to Traditional Chinese medical theory and modern pharmacological research result, repeated screening medicine for external use, is configured to Chinese medicine eye cream, has blood circulation promoting and blood stasis dispelling, improving acuity of vision and removing nebula, temperature promoting blood circulation, and skin-active is subsided a swelling, blood-nourishing and freckle-removing, the effect of the skin that compacts. Can effectively expand peripheral vessel, improve face microcirculation near the eyes, blood stasis dispelling of subsiding a swelling, pigmentation is had certain inhibitory action.

Clinical trial

Illustrate: my institute, in March ,-2014 in March, 2011, uses self-control eye cream treatment eye pouch, eye edema, and evident in efficacy, existing report is as follows.

Clinical data: clinic chooses eye pouch, canthus wrinkle obvious person 30 example. Wherein male 22 people, women 38 people. Age 25-55 year, average 33.2 years old; Unmarried 11 example, the married 49 example, do not educate person 36 example; The course of disease 6 months-12 years, average 5.33 years; Educational level University Culture 37 people, white collar, teacher, cadre, office staff 32 example, other staff 12 example. Readme is often stayed up late 23 examples of playing games, and heredity 35 is fallen, and 10 examples of having a sleepless night, daily maintenance is 23 people near the eyes, and laser therapy eye pouch recurs 8 people. Clinic is divided into treatment group 25 example, matched group 25 example.

Therapeutic Method: treatment group adopts homemade traditional Chinese drug eye cream, Fang Yong: Herba Centellae 30g, Rhizoma Typhonii 11g, Radix Angelicae Sinensis 10g, Poria 11g, Radix Notoginseng 12g, Radix Salviae Miltiorrhizae 13g, Semen Persicae 11g, Radix Ginseng 12g, Rhizoma Chuanxiong 12g, Radix Paeoniae Rubra 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 11g, Bombyx Batryticatus 11g, Rhizoma Corydalis 12g, Caulis Spatholobi 12g, Radix Angelicae Dahuricae 10g, Rhizoma Cyperi 11g, Flos Inulae 11g, Rhizoma Polygonati Odorati 13g, Flos Pelargonii 12g, Flos Matricariae chamomillae 12g, Herba Euphrasiae Regelii 11g, Faeces Passeris 12g, prepare into eye cream by the method for embodiment 2.

Take eye cream matched group, often organize 50 examples, use new seven supercilious look frosts of commercially available herborist respectively.

Operating process: when carrying out in the flat bed of personnel, with 3% hydrogen peroxide cleaning face, with negative ion atomizer spraying face, coordinate meridian point massage 12 methods to carry out facial massage simultaneously, near the eyes local do emphasis massage, the time be about 10min. after take eye cream, be uniformly applied to eyelid surrounding, note not doing into eyes, can suitably massage 10-15 minute. Once a day, within 1 month, it was 1 course for the treatment of. After terminating the course for the treatment of, monthly follow up a case by regular visits to 1 time, follow up a case by regular visits to continuously 3 months. Advise patient sun-proof during treatment, take a good rest, and disable other eye cream, eye cream.

Criterion of therapeutical effect

Effective: after treating for 2 courses for the treatment of, eye pouch, canthus wrinkle substantially disappear, and curative effect maintains more than 1 month, and eyestrain is alleviated; Taking a turn for the better: canthus wrinkle, eye pouch is substantially thin out, disappears more than 50%, the conscious satisfaction of patient, and sleep quality is good; Or eye pouch disappears during treatment, but it is bad to follow up a case by regular visits to middle sleep, and overtime work has again recurrence; Invalid: eye pouch, eye edema change inconspicuous or unchanged; Or once disappeared more than 50%, but substantially increase the weight of in following up a case by regular visits to, testing crew is unsatisfied with.

Therapeutic outcome: treatment group total effective rate compares with each matched group, difference all has significance (P < 0.01), illustrates that self-control eye cream curative effect is substantially better than commercially available eye cream. Refer to table 1

13 groups of Comparison of therapeutic tables of table

Note: compare * P < 0.01 with other each group

Follow-up results follows up a case by regular visits to discovery, and massage person is better than the personage not massaged. After recurrence, if being continuing with still effective.

Illustrate: the present invention is with reference to the achievement of Chinese medicine pharmacological research at all times, the natural Chinese medicine that screening inrigorating qi and promoting blood circulation, liver heat removing and eyesight improving, nourishing liver and kidney, improving acuity of vision and removing nebula, suppressing the hyperactive liver and subsiding YANG, heat-clearing and toxic substances removing, detumescence dewater, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, regulate the metabolism function of human body, improve human body periocualr skin blood circulation, thus reaching detumescence blood stasis dispelling, fatigue alleviating, eye skin of compacting. Desalination eye pouch, beautifies the purpose of appearance. The present invention, according to Traditional Chinese medical theory and modern pharmacological research result, repeated screening medicine for external use, is configured to Chinese medicine eye cream, has blood circulation promoting and blood stasis dispelling, improving acuity of vision and removing nebula, temperature promoting blood circulation, and skin-active is subsided a swelling, blood-nourishing and freckle-removing, the effect of the skin that compacts. Can effectively expand peripheral vessel, improve face microcirculation near the eyes, blood stasis dispelling of subsiding a swelling, pigmentation is had certain inhibitory action. Herba Centellae has a heat-clearing and toxic substances removing, inducing diuresis and reducing edema, nourishing, antiinflammatory, quelling effect. Deep skin cell can be stimulated to substitute. Herba Centellae can be compacted epidermis and corium coupling part, skin can be made to limber up, contribute to solving cutis laxa phenomenon, make skin smooth flexible; Promoting that in skin corium, collagen protein is formed, and makes fibrin regenerate, reconnect is got up, and makes skin reach smooth effect of compacting. Also assist in impaired organization healing and consolidation skin. Being closely connected between epidermis with corium can be promoted, the increase of adipose cell can be suppressed again, it is prevented that hydroderma, appearance obesity.

Claims (10)

1. alleviate eye wrinkle-removing for one kind, the Herba Centellae eye cream of eye pouch, it is characterized in that, described Herba Centellae eye cream includes the crude drug of following parts by weight: Herba Centellae 10��50 parts, Rhizoma Typhonii 10��20 parts, Radix Angelicae Sinensis 10��20 parts, Poria 10��20 parts, Radix Notoginseng 10��20 parts, Radix Salviae Miltiorrhizae 10��20 parts, 10��20 parts of Semen Persicae, Radix Ginseng 10��20 parts, Rhizoma Chuanxiong 10��20 parts, Radix Paeoniae Rubra 10��20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��20 parts, Bombyx Batryticatus 10��20 parts, Rhizoma Corydalis 10��20 parts, Caulis Spatholobi 10��20 parts, the Radix Angelicae Dahuricae 10��20 parts, Rhizoma Cyperi 10��20 parts, Flos Inulae 10��20 parts, Rhizoma Polygonati Odorati 10��20 parts, Flos Pelargonii 10��20 parts, Flos Matricariae chamomillae 10��20 parts, Herba Euphrasiae Regelii 10��20 parts, Faeces Passeris 10��20 parts.

2. alleviate eye wrinkle-removing according to claim 1, the Herba Centellae eye cream of eye pouch, it is characterized in that, described Herba Centellae eye cream includes the crude drug of following parts by weight: Herba Centellae 10��40 parts, Rhizoma Typhonii 10��15 parts, Radix Angelicae Sinensis 10��15 parts, Poria 10��15 parts, Radix Notoginseng 10��15 parts, Radix Salviae Miltiorrhizae 10��15 parts, 10��15 parts of Semen Persicae, Radix Ginseng 10��15 parts, Rhizoma Chuanxiong 10��15 parts, Radix Paeoniae Rubra 10��15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��15 parts, Bombyx Batryticatus 10��20 parts, Rhizoma Corydalis 10��20 parts, Caulis Spatholobi 10��20 parts, the Radix Angelicae Dahuricae 10��20 parts, Rhizoma Cyperi 10��20 parts, Flos Inulae 10��20 parts, Rhizoma Polygonati Odorati 10��20 parts, Flos Pelargonii 10��20 parts, Flos Matricariae chamomillae 10��20 parts, Herba Euphrasiae Regelii 10��20 parts, Faeces Passeris 10��20 parts.

3. alleviate eye wrinkle-removing according to claim 1, the Herba Centellae eye cream of eye pouch, it is characterized in that, described Herba Centellae eye cream includes the crude drug of following parts by weight: Herba Centellae 10��50 parts, Rhizoma Typhonii 10��20 parts, Radix Angelicae Sinensis 10��20 parts, Poria 10��20 parts, Radix Notoginseng 10��20 parts, Radix Salviae Miltiorrhizae 10��20 parts, 10��20 parts of Semen Persicae, Radix Ginseng 10��20 parts, Rhizoma Chuanxiong 10��20 parts, Radix Paeoniae Rubra 10��20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10��20 parts, Bombyx Batryticatus 10��15 parts, Rhizoma Corydalis 10��15 parts, Caulis Spatholobi 10��15 parts, the Radix Angelicae Dahuricae 10��15 parts, Rhizoma Cyperi 10��15 parts, Flos Inulae 10��15 parts, Rhizoma Polygonati Odorati 10��15 parts, Flos Pelargonii 10��15 parts, Flos Matricariae chamomillae 10��15 parts, Herba Euphrasiae Regelii 10��15 parts, Faeces Passeris 10��15 parts.

4. the preparation method of the Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch as according to any one of claims 1 to 3, it is characterised in that described preparation method comprises the following steps:

A. the preparation of Herba Centellae, extracts, as component 1;

B. take Radix Notoginseng, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the Rhizoma Cyperi way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 2;

C. by all the other crude drug soak with ethanol, extract, as component 3;

D., component 1, component 2 adding after mixing with component 3 Cera Flava be in harmonious proportion, sterilize tinning.

5. the preparation method alleviating the Herba Centellae eye cream of eye wrinkle-removing, eye pouch according to claim 4, it is characterised in that in described step a, takes the Herba Centellae chopping will plucked spring and summer, crosses 80-100 mesh sieve.

6. the preparation method alleviating the Herba Centellae eye cream of eye wrinkle-removing, eye pouch according to claim 4, it is characterized in that, in described step a, farther include the step extracted, medicated powder has been placed in lid stainless steel cask, has added 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, make abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 1.

7. the preparation method alleviating the Herba Centellae eye cream of eye wrinkle-removing, eye pouch according to claim 4, it is characterized in that, in described step b, take Radix Notoginseng, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the Rhizoma Cyperi way of distillation and be vaporized into crystallization, pulverized 120-150 order dusting cover stand-by, as component 2.

8. the preparation method alleviating the Herba Centellae eye cream of eye wrinkle-removing, eye pouch according to claim 4, it is characterized in that, in described step c, all the other raw materials described are cut into coarse powder, medicated powder have been placed in lid stainless steel cask, add 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, make abundant expansion; Drug sample after moistening expansion is mixed after paving pine by filter plate gauze bag parcel again bottom percolator do to dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, 2/3 eminence that must not exceed percolator loaded by medicated powder; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow 2��3ml per minute, filtrate puts into liquid container, and ethanol during by emptying pours liquid container into; Percolate is merged and stands. Heating is concentrated into paste, stand for standby use, becomes component 3.

9. the preparation method alleviating the Herba Centellae eye cream of eye wrinkle-removing, eye pouch according to claim 4, it is characterised in that in described step d, first blending ingredients 1, component 2 stir with component 3, add Cera Flava eye cream, and ultraviolet sterilization is bottled.

10. the using method of the Herba Centellae eye cream alleviating eye wrinkle-removing, eye pouch according to any one of claim 1��9, it is characterized in that, its usage is, after each face cleaning just before going to bed, by eye cream uniform application near the eyes, and massaging near the eyes 15-20 minute by middle finger finger belly, after fully absorbing to it, getting up early in second day washes away.