CN105732813A - 识别癌细胞上表达的cd-43和cea的含糖表位的抗体及其使用方法 - Google Patents
识别癌细胞上表达的cd-43和cea的含糖表位的抗体及其使用方法 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
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- C—CHEMISTRY; METALLURGY
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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Landscapes
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| CN105177091A (zh) | 2006-03-31 | 2015-12-23 | 中外制药株式会社 | 用于纯化双特异性抗体的抗体修饰方法 |
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| RU2461572C2 (ru) * | 2006-06-07 | 2012-09-20 | Биоэллаенс К.В. | Антитела, распознающие содержащий углеводы эпитоп на cd-43 и сеа, экспрессируемых на злокачественных клетках, и способы их применения |
| ES2719728T3 (es) | 2007-09-04 | 2019-07-12 | Compugen Ltd | Polipéptidos y polinucleótidos, y usos de los mismos como una diana farmacológica para producir fármacos y agentes biológicos |
| KR102339457B1 (ko) | 2007-09-26 | 2021-12-14 | 추가이 세이야쿠 가부시키가이샤 | 항체 정상영역 개변체 |
| CN106519025B (zh) | 2007-09-26 | 2021-04-23 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
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| CN105764922B (zh) | 2013-09-27 | 2020-07-17 | 中外制药株式会社 | 多肽异源多聚体的制备方法 |
| EP2871190A1 (en) * | 2013-11-11 | 2015-05-13 | ATLAB Pharma | Antibody against GD2-O-acetylated ganglioside with pro-apoptotic activity |
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| KR20250078589A (ko) * | 2015-06-24 | 2025-06-02 | 크링 바이오테라퓨틱스 비.브이. | Aml 항원 및 이의 용도 |
| KR101981943B1 (ko) | 2015-10-12 | 2019-05-24 | 주식회사 에이프로젠케이아이씨 | 항-cd43 항체 및 이의 암 치료 용도 |
| US20180363000A1 (en) * | 2015-12-14 | 2018-12-20 | The Trustees Of The University Of Pennsylvania | Aav-anti pcsk9 antibody constructs and uses thereof |
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| US20200023072A1 (en) | 2016-10-11 | 2020-01-23 | Medimmune Limited | Antibody-drug conjugates with immune-mediated therapy agents |
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| US12054558B2 (en) * | 2018-05-23 | 2024-08-06 | The Jackson Laboratory | Anti-NGly-1 antibodies and methods of use |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| AU2019401647A1 (en) | 2018-12-21 | 2021-07-08 | Multitude Inc. | Antibodies specific to MUC18 |
| AU2019401657B2 (en) * | 2018-12-21 | 2025-10-09 | Multitude Therapeutics Inc. | Antibodies specific to MUC18 |
| WO2021081515A2 (en) * | 2019-10-25 | 2021-04-29 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of human immunodeficiency virus |
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| WO2022078524A2 (en) | 2021-11-03 | 2022-04-21 | Hangzhou Dac Biotech Co., Ltd. | Specific conjugation of an antibody |
| CN118696059A (zh) | 2021-11-17 | 2024-09-24 | 美国全心医药生技股份有限公司 | 使用抗psgl-1抗体与jak抑制剂的组合治疗t细胞介导的炎症性疾病或癌症的方法 |
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| WO2009079649A1 (en) | 2009-06-25 |
| US20090191221A1 (en) | 2009-07-30 |
| TW200938629A (en) | 2009-09-16 |
| RU2010129423A (ru) | 2012-01-27 |
| CA2706502C (en) | 2018-08-07 |
| SG186669A1 (en) | 2013-01-30 |
| DK2245063T3 (en) | 2015-12-07 |
| IL205487A (en) | 2017-02-28 |
| KR101672271B1 (ko) | 2016-11-03 |
| CA2706502A1 (en) | 2009-06-25 |
| AU2008338313A1 (en) | 2009-06-25 |
| KR20100097661A (ko) | 2010-09-03 |
| ES2550757T3 (es) | 2015-11-12 |
| NZ585959A (en) | 2012-09-28 |
| EP2245063B1 (en) | 2015-08-26 |
| RU2528738C2 (ru) | 2014-09-20 |
| US9334329B2 (en) | 2016-05-10 |
| US8568718B2 (en) | 2013-10-29 |
| AU2008338313B2 (en) | 2014-01-16 |
| JP5568478B2 (ja) | 2014-08-06 |
| US20110280888A1 (en) | 2011-11-17 |
| US7982017B2 (en) | 2011-07-19 |
| IL205487A0 (en) | 2010-12-30 |
| JP2013247963A (ja) | 2013-12-12 |
| US20140105899A1 (en) | 2014-04-17 |
| BRPI0820452A2 (pt) | 2015-06-16 |
| EP2245063A1 (en) | 2010-11-03 |
| HK1150167A1 (en) | 2011-11-04 |
| JP2011505875A (ja) | 2011-03-03 |
| TWI439545B (zh) | 2014-06-01 |
| HUE026846T2 (en) | 2016-08-29 |
| CN101918448A (zh) | 2010-12-15 |
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