CN105726387A - Skin whitening microemulsion - Google Patents
Skin whitening microemulsion Download PDFInfo
- Publication number
- CN105726387A CN105726387A CN201610089251.0A CN201610089251A CN105726387A CN 105726387 A CN105726387 A CN 105726387A CN 201610089251 A CN201610089251 A CN 201610089251A CN 105726387 A CN105726387 A CN 105726387A
- Authority
- CN
- China
- Prior art keywords
- oil
- extract
- whitening
- quintessence oil
- microemulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a skin whitening microemulsion. More specifically, the skin whitening microemulsion contains sorbitan sesquioleate and PEG-20 sorbitan oleate; one or more oily components selected from hydrocarbon oil, synthetic grease, animal or vegetable oil, silicone oil and a mixture of silicone oil; polyhydric alcohol and water; one or more water-soluble skin whitening raw materials. The prepared skin whitening microemulsion is a water-in-oil system, is good in stability, can be stored for a long term, has a good solubilization effect on the water-soluble skin whitening raw materials, and can be made into a product containing high effective ingredients.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of whitening microemulsion.
Background technology
Bright and clean, pale, ruddy skin is always what Nails was pursued, the most in recent years China and Japan, the southeast
The fashion that Ya Deng state women praises highly, whitening has become as one of emphasis of cosmetics research and development.Along with the progress of technology, people research and develop
Going out whitening product miscellaneous, whitening essential oil is exactly the category that one of them is important.But there is the plant of white-skinned face function
Active constituent content in quintessence oil is on the low side, will realize preferable whitening effect and need to add substantial amounts of plants essential oil, the plant of excess
Quintessence oil interpolation often results in fragrance overrich, has a strong impact on use sense, and for promoting effect of whitening essential oil, usual way is interpolation one
A little oil-soluble skin-lightening cosmetic raw materials, such as tetrahexyldecyl ascorbate, but, most whitening raw material belongs to insoluble
In the water-soluble material of oil preparation, this causes being difficult to during whitening essential oil Formula Development apply water solublity whitening raw material, selectable former
Material is restricted, it is difficult to realize good white-skinned face function.
Summary of the invention
Based on this, the main object of the present invention is water-soluble for being difficult to apply during the exploitation of whitening essential oil in prior art
The problem of property whitening raw material provides a solution.
In order to solve above-mentioned technical problem, the present invention is achieved through the following technical solutions:
A kind of whitening microemulsion, contains:
(a) two kinds of nonionic emulsifiers: sorbitan sesquioleate and PEG-20 sorbitan monooleate；
B () one or more of oily components, selected from hydrocarbon ils, synthesis grease, vegetable and animals oils, silicone oil and mixture thereof；
(c) polynary alcohol and water；
(d) one or more of water solublity whitening raw material；Wherein sorbitan sesquioleate and PEG-20 anhydrous sorbitol oleic acid
The ratio of ester is (3:1)-(5:1), and emulsifying agent is the dense of (1:1)-(3:1), emulsifying agent and oily components with the ratio of oily components
Degree summation is more than 75wt%.
Preferably, the ratio of sorbitan sesquioleate and PEG-20 sorbitan monooleate is 5:1.5, emulsifying agent with
The ratio of oily components is 2:1.
In a preferred embodiment of the invention, described hydrocarbon ils is white mineral oil, vaseline, C15-19 alkane, hydrogenates the poly-last of the ten Heavenly stems
Alkene, 2-Methylpentadecane, polyethylene, Parleam, paraffin, Fancol ID, squalane, ceresine, the one of vaccenic acid or
Plant above mixing.
In a preferred embodiment of the invention, described synthesis grease is that myristyl alcohol myristinate, caprylic/capric are sweet
Oil three esters, isopropyl myristate, isononyl isononanoate, ethylhexyl palmitate, glycol distearate, glycerol three (second
Base caproic acid) ester, spermol ethylhexoate, Dermol DIPS, Dermol 105, three different nonyl essences, dicaprylyl carbonate,
C12-15 alcohol benzoate, propylene glycol carbonate, one or more mixing of isopropyl isostearate.
In a preferred embodiment of the invention, described vegetable and animals oils is lanoline, fat of Oromaius norvaehollandeae, horse fat, Oleum Hippophae, Rhizoma Zingiberis Recens
Root oil, soybean oil, safflower oil, olive oil, Radix Oenotherae erythrosepalae oil, Rosehips oil, American Avocado Tree oil, Jojoba oil, Oleum Vitis viniferae, Bai Chihua
Seed oil, deep-sea two save shepherd's purse seed oil, Butyrospermum parkii fruit fatty oil, cocoa seed fat, macadimia nut seed oil, camellia seed oil, Petiolus Trachycarpi oil, Petiolus Trachycarpi
A kind of in core oil, camellia seed oil, Rosa Canina fruit oil, Semen Tritici aestivi germ oil, Semen pruni armeniacae oil or their mixing.
In a preferred embodiment of the invention, described silicone oil is ring five polydimethylsiloxane, trimethyl silicane alkoxyl
Esters of silicon acis, polydimethylsiloxane, dimethiconol, phenyl trimethicone, cetyl polydimethylsiloxanes
Alkane, caprylyl methicone, one or more mixing of stearyl dimethione.
In a preferred embodiment of the invention, described polyhydric alcohol be glycerol, propylene glycol, butanediol, pentanediol, oneself two
Alcohol, sorbitol, ethanol, PEG-8, Polyethylene Glycol-32, dipropylene glycol, diglycerol, glycerin polyether-26, Natrulon H-10,
One or more mixing of polyglycereol-8.
In a preferred embodiment of the invention, described water solublity whitening raw material is ascorbic acid glucoside, 3-o-ethoxy
Base ascorbic acid, Trenaxmine, nicotiamide, glabridin, alpha-arbutin, β-arbutin, Symwhite-337, resveratrol,
Phloretin, lactobacillus fermentation lysate, yogurt extract, Fructus Phyllanthi extract, daisy extract, Azelaic Acid glycine two
Potassium, Herba Centellae extract, sodium ascorbyl phosphate, vitamin C, vitamin C phosphoric ester potassium, yeast extract, Radix Mori skin extract
Thing, Radix Sangusorbae extract, Rhizoma Saururi extract, Rhizoma Atractylodis Macrocephalae extract, Radix Angelicae Sinensis extract, Rhizoma Chuanxiong extract, Pseudobulbus Bletillae (Rhizoma Bletillae) extract, Agkistrodon
Diffusa extract, Folium Ginkgo extract, Radix Ginseng Rubra extract, Radix Glycyrrhizae extract, Rhizoma Alismatis extract, the one of Herba Asari extract or
Plant above mixing.
Preferably, described water solublity whitening raw material contains daisy extract, Herba Hedyotidis Diffusae extract and Radix Sangusorbae extract,
The addition of described daisy extract is 0.1-0.5wt%, and the addition of described Herba Hedyotidis Diffusae extract is 0.1-
0.5wt%, the addition of described Radix Sangusorbae extract is 0.1-0.5wt%.
The inventors found that daisy extract, Herba Hedyotidis Diffusae extract and Radix Sangusorbae extract are significant due to it
Synergistic function, the lightening compositions obtained has the whitening effect being obviously improved.
It is further preferred that described water solublity whitening raw material can also contain Radix Ginseng Rubra extract and Radix Angelicae Sinensis extract, described
The addition of Radix Ginseng Rubra extract be 0.1-0.5wt%, the addition of described Radix Angelicae Sinensis extract is 0.1-0.5wt%.
The inventors found that the mixing of Radix Ginseng Rubra extract and Radix Angelicae Sinensis extract has good promotion to white-skinned face function
Effect.
The microemulsion of the present invention can be prepared by conventional production technology, following preparation method, preparation technology bag
Include following steps: the mixing of sorbitan sesquioleate, PEG-20 sorbitan monooleate and oily components is constituted oil by (1)
Phase, is heated to 85 DEG C, stirring and dissolving by oil phase；The mixing of polyhydric alcohol, water and water solublity whitening raw material is constituted aqueous phase, aqueous phase is added
Hot to 85 DEG C, stirring and dissolving；(2) under quickly stirring (mixing speed 50rpm), aqueous phase is slowly added to oil phase, stirs；
(3) ultrasonic Treatment using frequency to be 1kHZ 5 minutes, are cooled to room temperature.
Present invention also offers a kind of whitening massage quintessence oil, including the component of following mass percent:
There is the plants essential oil 0.01-1% of white-skinned face function
Vitamin E acetate 0.1-1%
Butylated hydroxytoluene 0.05-0.2%
Above-mentioned whitening microemulsion 0.1-5%
Vegetable oil surplus.
In a preferred embodiment of the invention, the described plants essential oil with white-skinned face function is Herba Lysimachiae foenum-graeci quintessence oil, lemon
Lemon grass quintessence oil, Bergamot, cumin essential oil, sandalwood essential oil, Peppermint essential oil, P-Cymene, five-leaved chaste tree quintessence oil, Acotus illicioides essence
Oil, Basil Essential, eryngo quintessence oil, Fructus Citri Limoniae quintessence oil, Bergamot, clove oil, cinnamon essential oil, shellflower leaf essential oil, gorgeous mountain
Rhizoma Zingiberis Recens seed quintessence oil, Rhizoma Alpiniae Officinarum quintessence oil, Rhizoma Curcumae Longae essential oil, Rhizoma Curcumae quintessence oil, ginger essential oil, Fructus Citri grandis quintessence oil, blue or green lemon quintessence oil, Basil Essential,
Zingiber casumnar quintessence oil, Flos Rosae Rugosae quintessence oil, Dianthus carryophyllus quintessence oil, hyacinth quintessence oil, Aleppo pine quintessence oil, Radix Oenotherae erythrosepalae quintessence oil, Semen Armeniacae Amarum
One or more mixing of quintessence oil.
Preferably, described plants essential oil is the mixing of lemon grass (Cymbopogon citratus) quintessence oil and Rhizoma Curcumae Longae essential oil, described lemon grass (Cymbopogon citratus) quintessence oil and
The mass ratio of Rhizoma Curcumae Longae essential oil is (1-10): (1-10).
In a preferred embodiment of the invention, described vegetable oil is Oleum Hippophae, Ginger Root oil, soybean oil, Semen Flos Carthami
Shepherd's purse seed is saved at oil, olive oil, Radix Oenotherae erythrosepalae oil, Rosehips oil, American Avocado Tree oil, Jojoba oil, Oleum Vitis viniferae, white Limnanthes Alba Seed Oil, deep-sea two
Oil, Butyrospermum parkii fruit fatty oil, cocoa seed fat, macadimia nut seed oil, camellia seed oil, Petiolus Trachycarpi oil, palm-kernel oil, camellia seed oil, certain herbaceous plants with big flowers
A kind of in flower seed oil, Rosa Canina fruit oil, Semen Tritici aestivi germ oil, Semen pruni armeniacae oil or their mixing.
Preferably, described vegetable oil is the mixing of Oleum Helianthi, Jojoba oil and Oleum Vitis viniferae, described sunflower seed
The mass ratio of oil, Jojoba oil and Oleum Vitis viniferae is (1-10): (1-10): (1-10).Oleum Helianthi, Jojoba oil and Semen Vitis viniferae
The use sense that can play of mixture of oil, and rich in nutritional labeling can play skin care, promote the metabolism of skin
Deng skin effect, white-skinned face function there is facilitation.
Compared with prior art, the method have the advantages that: the microemulsion of the present invention has good stability, can be long-term
Storage；Water solublity whitening raw material there is is good solubilization, the product higher containing functional component can be made；The present invention is made
Standby microemulsion is water-in-oil system, can be used alone, and is also added in oil-type skin-lightening cosmetic, easy to use；This
Bright preparation technology is simple, it is easy to produce.
Detailed description of the invention
For a more detailed description to the present invention below in conjunction with detailed description of the invention, but embodiments of the present invention are not limited to
This, for the technological parameter indicated the most especially or condition, can refer to routine techniques and carry out.
Embodiment 1
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 3kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1kg, Fancol ID 2kg, glycerol 1kg, nicotiamide 0.1kg, water 0.5kg；
Preparation technology: the mixing of sorbitan sesquioleate, PEG-20 sorbitan monooleate and Fancol ID is constituted by (1)
Oil phase, is heated to 85 DEG C, stirring and dissolving by oil phase；The mixing of glycerol, water and Herba portulacae extract is constituted aqueous phase, by heated aqueous
To 85 DEG C, stirring and dissolving；(2) under quickly stirring (mixing speed 50rpm), aqueous phase is slowly added to oil phase, stirs；(3)
The ultrasonic Treatment using frequency to be 1kHZ 5 minutes, is cooled to room temperature.
Embodiment 2
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, Herba Asari extract 0.5kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 3
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 4kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1kg, Jojoba oil 2kg, horse fat 0.1kg, phenyl trimethicone 0.2kg, hydrogenated polydecene 2.7kg, propylene glycol
1kg, arbutin 0.1kg, Radix Mori peel extract 0.1kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 4
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1kg, polydimethylsiloxane 0.1kg, caprylic/capric triglyceride 0.4kg, Radix Oenotherae erythrosepalae oil 0.5kg, butanediol 0.5kg, white
And extract 0.3kg, water 0.6kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 5
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, daisy extract 0.5kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 6
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, Herba Hedyotidis Diffusae extract 0.5kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 7
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, Radix Sangusorbae extract 0.5kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 8
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, Radix Sangusorbae extract 0.1kg, daisy extract 0.1kg, spend in vain
Herba Hedyotidis Diffusae extract 0.3kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 9
A kind of microemulsion, it includes the component of following quality: sorbitan sesquioleate 5kg, PEG-20 anhydrous sorbitol oleic acid
Ester 1.5kg, isononyl isononanoate 3kg, PEG-8 1.5kg, Radix Sangusorbae extract 0.1kg, daisy extract 0.1kg, spend in vain
Herba Hedyotidis Diffusae extract 0.3kg, Radix Ginseng Rubra extract 0.1kg, Radix Angelicae Sinensis extract 0.1kg, water 0.5kg；
Preparation technology: similar embodiment 1, does not repeats them here.
Embodiment 10
A kind of whitening massage quintessence oil, including the component of following mass percent:
Herba Lysimachiae foenum-graeci quintessence oil 0.01%
Basil Essential 0.5%
Vitamin E acetate 1%
Butylated hydroxytoluene 0.05%
Whitening microemulsion 5% prepared by embodiment 1
Oleum Hippophae surplus.
Preparation technology: butylated hydroxytoluene is mixed with Oleum Hippophae, heating for dissolving, then it is cooled to room temperature, sequentially adds
Whitening microemulsion prepared by Herba Lysimachiae foenum-graeci quintessence oil, Vitamin E acetate, embodiment 5, stirs.
Embodiment 11
A kind of whitening massage quintessence oil, including the component of following mass percent:
Sandalwood essential oil 1%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 0.1% prepared by embodiment 2
Olive oil 20%
Camellia seed oil surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 12
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.5%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 5
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 13
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.5%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 6
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 14
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.5%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 7
Oleum Helianthi surplus.
Preparation technology similar embodiment 15, does not repeats them here.
Embodiment 15
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.5%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 8
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 16
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.5%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 9
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 17
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.2%
Sandalwood essential oil 0.3%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 9
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 18
A kind of whitening massage quintessence oil, including the component of following mass percent:
Lemon grass (Cymbopogon citratus) quintessence oil 0.2%
Sandalwood essential oil 0.3%
Vitamin E acetate 0.1%
Butylated hydroxytoluene 0.2%
Whitening microemulsion 1% prepared by embodiment 9
Jojoba oil 30%
Oleum Vitis viniferae 20%
Oleum Helianthi surplus.
Preparation technology similar embodiment 10, does not repeats them here.
Embodiment 19
Experiment one, stability test
Whitening microemulsion obtained by embodiment 1-9 is carried out stability test.Method of testing: test object is placed on-15
DEG C, place respectively one month under room temperature and 45 DEG C of environment after observe, with invariant color, without Precipitation, free from extraneous odour as criterion of acceptability.
Experimental result: observed after 1 month, finds that the whitening microemulsion obtained by embodiment 1-9 is the most qualified.As can be seen here, this
Bright prepared microemulsion is stable.
Experiment two, whitening effect test
Whitening essential oil prepared by embodiment 12-18 is carried out efficacy assessments, and with commercially available whitening essential oil for comparative example 1.Test
Object: each experimental group is 10 women, 30-55 year, it is possible to by Normalization rule cosmetics, and cooperating personnel are the completeest
Become appraisal, there is certain expressive faculty, the impression after energy actual response use；Test zone: facial skin；Use: every
It uses twice, uses 48 days continuously；Evaluation criterion: effective, effectively, invalid, concrete, by the 0th day and the photograph of the 48th day
The judgement substantially bleached that compares is effective；It is effective for having, by the photograph contrast of the 0th day and the 48th day, the judgement necessarily bleached；
Bleaching inconspicuous by the photograph contrast of the 0th day and the 48th day, it is invalid to be judged as.Concrete test result is shown in Table 1.
Table 1 whitening test result table
| Effective | Effectively | Invalid | |
| Embodiment 12 | 4 | 3 | 3 |
| Embodiment 13 | 3 | 3 | 4 |
| Embodiment 14 | 5 | 2 | 3 |
| Embodiment 15 | 7 | 2 | 1 |
| Embodiment 16 | 8 | 2 | 0 |
| Embodiment 17 | 9 | 1 | 0 |
| Embodiment 18 | 10 | 0 | 0 |
| Comparative example 1 | 3 | 3 | 4 |
Knowable to upper table 1, the whitening massage quintessence oil prepared by embodiment 12-18 and commercially available prod comparative example 1 efficacy test result
Relatively understanding, the whitening massage oil obtained by the present invention has good whitening effect；Embodiment 15 and the whitening of embodiment 12-14
Test result contrast understands, and daisy extract, Herba Hedyotidis Diffusae extract and Radix Sangusorbae extract have significant Synergistic and make
With, the lightening compositions obtained has the whitening effect being obviously improved；Embodiment 16 and 15 whitening test result understands, and Radix Ginseng Rubra carries
The mixing taking thing and Radix Angelicae Sinensis extract has good facilitation to white-skinned face function.Embodiment 17 and 16 whitening test result can
Knowing, the mixing of lemon grass (Cymbopogon citratus) quintessence oil and Rhizoma Curcumae Longae essential oil can promote whitening effect further.Embodiment 18 and 17 whitening test result can
Know, the further whitening facilitation effect that is mixed with of Oleum Helianthi, Jojoba oil and Oleum Vitis viniferae is described.
The above, be only presently preferred embodiments of the present invention, and the present invention not does any pro forma restriction, therefore
All contents without departing from technical solution of the present invention, any simply repair made for any of the above embodiments according to the technical spirit of the present invention
Change, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (10)
1. a whitening microemulsion, it is characterised in that contain:
(a) two kinds of nonionic emulsifiers: sorbitan sesquioleate and PEG-20 sorbitan monooleate；
B () one or more of oily components, selected from hydrocarbon ils, synthesis grease, vegetable and animals oils, silicone oil and mixture thereof；
(c) polynary alcohol and water；
(d) one or more of water solublity whitening raw material；Wherein sorbitan sesquioleate and PEG-20 anhydrous sorbitol oleic acid
The ratio of ester is (3:1)-(5:1), and emulsifying agent is the dense of (1:1)-(3:1), emulsifying agent and oily components with the ratio of oily components
Degree summation is more than 75wt%.
Whitening microemulsion the most according to claim 1, it is characterised in that described sorbitan sesquioleate and PEG-20
The ratio of sorbitan monooleate is 5:1.5, and emulsifying agent is 2:1 with the ratio of oily components.
Whitening microemulsion the most according to claim 1, it is characterised in that described water solublity whitening raw material is ascorbic acid
Glucoside, 3-o-ethoxy ascorbic acid, Trenaxmine, nicotiamide, glabridin, alpha-arbutin, β-arbutin, phenethyl isophthalic
Diphenol, resveratrol, phloretin, lactobacillus fermentation lysate, yogurt extract, Fructus Phyllanthi extract, daisy extract,
Azelaic Acid glycine dipotassium, Herba Centellae extract, sodium ascorbyl phosphate, vitamin C, vitamin C phosphoric ester potassium, yeast carry
Take thing, Radix Mori peel extract, Radix Sangusorbae extract, Rhizoma Saururi extract, Rhizoma Atractylodis Macrocephalae extract, Radix Angelicae Sinensis extract, Rhizoma Chuanxiong extract, white
And extract, Herba Hedyotidis Diffusae extract, Folium Ginkgo extract, Radix Ginseng Rubra extract, Radix Glycyrrhizae extract, Rhizoma Alismatis extract, Herba Asari
One or more mixing of extract.
Whitening microemulsion the most according to claim 3, it is characterised in that described water solublity whitening raw material contains Bellis perennis and carries
Taking thing, Herba Hedyotidis Diffusae extract and Radix Sangusorbae extract, the addition of described daisy extract is 0.1-0.5wt%, described
The addition of Herba Hedyotidis Diffusae extract is 0.1-0.5wt%, and the addition of described Radix Sangusorbae extract is 0.1-0.5wt%.
Whitening microemulsion the most according to claim 4, it is characterised in that described water solublity whitening raw material can also contain
Radix Ginseng Rubra extract and Radix Angelicae Sinensis extract, the addition of described Radix Ginseng Rubra extract is 0.1-0.5wt%, described Radix Angelicae Sinensis extract
Addition be 0.1-0.5wt%.
6. the preparation method of the whitening microemulsion described in an any one of claim 1-5, it is characterised in that described preparation side
Method comprises the following steps: (1) is by sorbitan sesquioleate, PEG-20 sorbitan monooleate and oily components mixing structure
Become oil phase, oil phase is heated to 85 DEG C, stirring and dissolving；The mixing of polyhydric alcohol, water and water solublity whitening raw material is constituted aqueous phase, by water
Heat phase to 85 DEG C, stirring and dissolving；(2) aqueous phase being slowly added under quickly stirring (mixing speed 50rpm) oil phase, stirring is all
Even；(3) ultrasonic Treatment using frequency to be 1kHZ 5 minutes, are cooled to room temperature.
7. a whitening massage quintessence oil, including the component of following mass percent:
There is the plants essential oil 0.01-1% of white-skinned face function
Vitamin E acetate 0.1-1%
Butylated hydroxytoluene 0.05-0.2%
The whitening microemulsion 0.1-5% of any one of claim 1-5
Vegetable oil surplus.
Whitening the most according to claim 7 massage quintessence oil, it is characterised in that the described plants essential oil with white-skinned face function
For Herba Lysimachiae foenum-graeci quintessence oil, lemon grass (Cymbopogon citratus) quintessence oil, Bergamot, cumin essential oil, sandalwood essential oil, Peppermint essential oil, P-Cymene, five-leaved chaste tree essence
Oil, Acotus illicioides quintessence oil, Basil Essential, eryngo quintessence oil, Fructus Citri Limoniae quintessence oil, Bergamot, clove oil, cinnamon essential oil, gorgeous mountain
Folium Zingiberis quintessence oil, shellflower seed quintessence oil, Rhizoma Alpiniae Officinarum quintessence oil, Rhizoma Curcumae Longae essential oil, Rhizoma Curcumae quintessence oil, ginger essential oil, Fructus Citri grandis quintessence oil, blue or green lemon essence
Oil, Basil Essential, zingiber casumnar quintessence oil, Flos Rosae Rugosae quintessence oil, Dianthus carryophyllus quintessence oil, hyacinth quintessence oil, Aleppo pine quintessence oil, see by the moon
Grass quintessence oil, one or more mixing of Semen Armeniacae Amarum quintessence oil.
Whitening the most according to claim 8 massage quintessence oil, it is characterised in that described plants essential oil be lemon grass (Cymbopogon citratus) quintessence oil and
The mixing of Rhizoma Curcumae Longae essential oil, described lemon grass (Cymbopogon citratus) quintessence oil and the mass ratio of Rhizoma Curcumae Longae essential oil are (1-10): (1-10).
Whitening the most according to claim 7 massage quintessence oil, it is characterised in that described vegetable oil be Oleum Helianthi, flash
Bar oil and the mixing of Oleum Vitis viniferae, the mass ratio of described Oleum Helianthi, Jojoba oil and Oleum Vitis viniferae is (1-10): (1-
10): (1-10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610089251.0A CN105726387A (en) | 2016-02-17 | 2016-02-17 | Skin whitening microemulsion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610089251.0A CN105726387A (en) | 2016-02-17 | 2016-02-17 | Skin whitening microemulsion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105726387A true CN105726387A (en) | 2016-07-06 |
Family
ID=56245951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610089251.0A Pending CN105726387A (en) | 2016-02-17 | 2016-02-17 | Skin whitening microemulsion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105726387A (en) |
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074271A (en) * | 2016-07-08 | 2016-11-09 | 珍尔姿（广州）化妆品有限公司 | A kind of have the sun-proof air cushion frost with spot-removal function |
| CN106309154A (en) * | 2016-09-30 | 2017-01-11 | 广东丸美生物技术股份有限公司 | Skin care substrate with long acting moisturizing and whitening effects and preparation and application of skin care substrate |
| CN107095820A (en) * | 2017-06-06 | 2017-08-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of saururus chinensis whitening emulsion |
| CN107320374A (en) * | 2017-07-12 | 2017-11-07 | 拉芳家化股份有限公司 | A kind of skin care milk containing curcumin analogue |
| CN107811881A (en) * | 2017-11-01 | 2018-03-20 | 武汉百思凯瑞纳米科技有限公司 | A kind of α ursin nano-compositions of whitening antioxidation and preparation method and application |
| CN108354864A (en) * | 2018-03-30 | 2018-08-03 | 浙江工业大学 | A kind of preparation method with the lotion of skin whitening, moisturizing |
| WO2018142033A1 (en) * | 2017-02-06 | 2018-08-09 | Ion Laboratoire | Depigmenting dermatological and cosmetic compositions |
| CN108379215A (en) * | 2018-03-30 | 2018-08-10 | 广州赛隽生物科技有限公司 | A kind of cosmetic composition for having effects that the freeze-drying compound powder of skin whitening and including the freeze-drying compound powder |
| WO2018152758A1 (en) * | 2017-02-24 | 2018-08-30 | 拉芳家化股份有限公司 | Anti-inflammatory emulsion |
| CN109121392A (en) * | 2017-04-13 | 2019-01-01 | 株式会社Adhome | Utilize the preparation method of the vegetable oil lotion of ultrasonication |
| CN109223651A (en) * | 2018-11-15 | 2019-01-18 | 天津郁美净集团有限公司 | A kind of skin care compositions and preparation method thereof with white-skinned face function |
| CN109288715A (en) * | 2018-11-27 | 2019-02-01 | 黄犟兵 | A kind of whitening remediation composition and preparation method thereof |
| CN109303756A (en) * | 2017-07-28 | 2019-02-05 | 陈静 | A kind of Rosa Damascana and preparation method thereof for repairing keratoderma |
| CN109620782A (en) * | 2018-11-02 | 2019-04-16 | 广州市爱百伊生物技术有限公司 | A kind of plant composition with Whitening, spot effect |
| CN109925248A (en) * | 2019-04-28 | 2019-06-25 | 青岛科技大学 | A kind of skin care compositions containing phloretin, the anti-skin photoage effect of arasaponin |
| CN110327273A (en) * | 2019-08-06 | 2019-10-15 | 苏格格 | Lightening compositions, Skin whitening care cosmetics and preparation method thereof |
| CN110623884A (en) * | 2019-10-25 | 2019-12-31 | 张赞红 | Anti-aging mulberry root-red ginseng speckle-lightening extracting solution and preparation method thereof |
| WO2020133948A1 (en) * | 2018-12-25 | 2020-07-02 | 衢州市益年堂农林科技有限公司 | Composition having whitening and anti-oxidation effects and skin care cream thereof |
| CN111419758A (en) * | 2020-05-07 | 2020-07-17 | 天津市康婷生物工程集团有限公司 | Whitening composition and preparation method thereof |
| CN111840205A (en) * | 2020-08-25 | 2020-10-30 | 广东丸美生物技术股份有限公司 | Multiple anti-aging composition, essence lotion and preparation method thereof |
| CN112472629A (en) * | 2020-12-16 | 2021-03-12 | 中国热带农业科学院农产品加工研究所 | Alpinia officinarum and amomum tsao-ko sun-proof emulsion and preparation method thereof |
| CN117646038A (en) * | 2024-01-30 | 2024-03-05 | 妙越缇卡生物医药科技(山东)有限公司 | Lactobacillus paracasei SF-L31 fermented product for whitening and lightening spots and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670445A (en) * | 2012-05-23 | 2012-09-19 | 成都鹏翔生物科技有限公司 | Chinese medicinal face repair cream and preparation method thereof |
| CN103340779A (en) * | 2013-06-25 | 2013-10-09 | 开平市美康泉生物科技有限公司 | Young skin activating lotion |
| CN104224633A (en) * | 2014-09-30 | 2014-12-24 | 河南科技大学 | Pure peony skin-care essential oil and preparation method thereof |
| CN104940084A (en) * | 2015-07-03 | 2015-09-30 | 北京枫华草木洗涤用品有限公司 | Pure natural after-bath massage oil |
-
2016
- 2016-02-17 CN CN201610089251.0A patent/CN105726387A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670445A (en) * | 2012-05-23 | 2012-09-19 | 成都鹏翔生物科技有限公司 | Chinese medicinal face repair cream and preparation method thereof |
| CN103340779A (en) * | 2013-06-25 | 2013-10-09 | 开平市美康泉生物科技有限公司 | Young skin activating lotion |
| CN104224633A (en) * | 2014-09-30 | 2014-12-24 | 河南科技大学 | Pure peony skin-care essential oil and preparation method thereof |
| CN104940084A (en) * | 2015-07-03 | 2015-09-30 | 北京枫华草木洗涤用品有限公司 | Pure natural after-bath massage oil |
Non-Patent Citations (1)
| Title |
|---|
| 佚名: "相宜本草红景天幼白隔离防护乳", 《HTTP://WWW.COSDNA.COM/CHS/COSMETIC_113E150317.HTML》 * |
Cited By (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074271A (en) * | 2016-07-08 | 2016-11-09 | 珍尔姿（广州）化妆品有限公司 | A kind of have the sun-proof air cushion frost with spot-removal function |
| CN106309154A (en) * | 2016-09-30 | 2017-01-11 | 广东丸美生物技术股份有限公司 | Skin care substrate with long acting moisturizing and whitening effects and preparation and application of skin care substrate |
| CN106309154B (en) * | 2016-09-30 | 2019-07-16 | 广东丸美生物技术股份有限公司 | One kind having long-acting moisturizing and white-skinned face function skin matrix and its preparation and application |
| WO2018142033A1 (en) * | 2017-02-06 | 2018-08-09 | Ion Laboratoire | Depigmenting dermatological and cosmetic compositions |
| FR3062569A1 (en) * | 2017-02-06 | 2018-08-10 | Ion Laboratoire | DEPIGMENTING DERMATOLOGICAL AND COSMETIC COMPOSITIONS |
| CN109121393A (en) * | 2017-02-24 | 2019-01-01 | 拉芳家化股份有限公司 | A kind of anti-inflammatory lotion |
| WO2018152758A1 (en) * | 2017-02-24 | 2018-08-30 | 拉芳家化股份有限公司 | Anti-inflammatory emulsion |
| CN109121392B (en) * | 2017-04-13 | 2021-08-24 | 株式会社Adhome | Method for preparing vegetable oil emulsion by ultrasonic treatment |
| CN109121392A (en) * | 2017-04-13 | 2019-01-01 | 株式会社Adhome | Utilize the preparation method of the vegetable oil lotion of ultrasonication |
| CN107095820A (en) * | 2017-06-06 | 2017-08-29 | 安徽吉乃尔电器科技有限公司 | A kind of preparation method of saururus chinensis whitening emulsion |
| CN107320374A (en) * | 2017-07-12 | 2017-11-07 | 拉芳家化股份有限公司 | A kind of skin care milk containing curcumin analogue |
| CN109303756A (en) * | 2017-07-28 | 2019-02-05 | 陈静 | A kind of Rosa Damascana and preparation method thereof for repairing keratoderma |
| CN107811881A (en) * | 2017-11-01 | 2018-03-20 | 武汉百思凯瑞纳米科技有限公司 | A kind of α ursin nano-compositions of whitening antioxidation and preparation method and application |
| CN108379215A (en) * | 2018-03-30 | 2018-08-10 | 广州赛隽生物科技有限公司 | A kind of cosmetic composition for having effects that the freeze-drying compound powder of skin whitening and including the freeze-drying compound powder |
| CN108354864A (en) * | 2018-03-30 | 2018-08-03 | 浙江工业大学 | A kind of preparation method with the lotion of skin whitening, moisturizing |
| CN109620782A (en) * | 2018-11-02 | 2019-04-16 | 广州市爱百伊生物技术有限公司 | A kind of plant composition with Whitening, spot effect |
| CN109620782B (en) * | 2018-11-02 | 2021-12-21 | 广州市爱百伊生物技术有限公司 | Plant composition with whitening and spot-fading effects |
| CN109223651A (en) * | 2018-11-15 | 2019-01-18 | 天津郁美净集团有限公司 | A kind of skin care compositions and preparation method thereof with white-skinned face function |
| CN109288715A (en) * | 2018-11-27 | 2019-02-01 | 黄犟兵 | A kind of whitening remediation composition and preparation method thereof |
| WO2020133948A1 (en) * | 2018-12-25 | 2020-07-02 | 衢州市益年堂农林科技有限公司 | Composition having whitening and anti-oxidation effects and skin care cream thereof |
| CN109925248B (en) * | 2019-04-28 | 2021-10-19 | 青岛科技大学 | A skin care composition containing phloretin and Panax notoginsenosides with skin photoaging resisting effect |
| CN109925248A (en) * | 2019-04-28 | 2019-06-25 | 青岛科技大学 | A kind of skin care compositions containing phloretin, the anti-skin photoage effect of arasaponin |
| CN110327273A (en) * | 2019-08-06 | 2019-10-15 | 苏格格 | Lightening compositions, Skin whitening care cosmetics and preparation method thereof |
| CN110327273B (en) * | 2019-08-06 | 2022-02-15 | 广州名妆化妆品制造有限公司 | Whitening composition, whitening skin care product and preparation method thereof |
| CN110623884A (en) * | 2019-10-25 | 2019-12-31 | 张赞红 | Anti-aging mulberry root-red ginseng speckle-lightening extracting solution and preparation method thereof |
| CN111419758A (en) * | 2020-05-07 | 2020-07-17 | 天津市康婷生物工程集团有限公司 | Whitening composition and preparation method thereof |
| CN111419758B (en) * | 2020-05-07 | 2022-12-20 | 天津市康婷生物工程集团有限公司 | Whitening composition and preparation method thereof |
| CN111840205A (en) * | 2020-08-25 | 2020-10-30 | 广东丸美生物技术股份有限公司 | Multiple anti-aging composition, essence lotion and preparation method thereof |
| CN112472629A (en) * | 2020-12-16 | 2021-03-12 | 中国热带农业科学院农产品加工研究所 | Alpinia officinarum and amomum tsao-ko sun-proof emulsion and preparation method thereof |
| CN117646038A (en) * | 2024-01-30 | 2024-03-05 | 妙越缇卡生物医药科技(山东)有限公司 | Lactobacillus paracasei SF-L31 fermented product for whitening and lightening spots and application thereof |
| CN117646038B (en) * | 2024-01-30 | 2024-04-19 | 妙越缇卡生物医药科技(山东)有限公司 | Lactobacillus paracasei SF-L31 fermented product for whitening and lightening spots and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105726387A (en) | Skin whitening microemulsion | |
| CN105708757A (en) | Antiallergic microemulsion | |
| CN104042528B (en) | Draft hair care anticreep anti-dandruff shampoo stock solution and manufacture method | |
| JP3415198B2 (en) | External preparation for skin | |
| CN105505635B (en) | A kind of skin cleansing composition and preparation method thereof containing lotus active constituent | |
| CN105496800A (en) | Semitransparent microemulsion | |
| CN103735468B (en) | A kind of cosmetics containing mosquito repellent composition microcapsule | |
| KR101196523B1 (en) | Composition for promoting hair growth comprising fermented oriental medicine extract | |
| CN105816389A (en) | Cosmetic composite with breast maintenance effect | |
| KR20090005479A (en) | Composition for promoting hair growth | |
| CN106176571A (en) | A kind of natural Haircare composition and preparation method thereof of originating | |
| CN104398465A (en) | Scalp care and cleaning liquid | |
| AU2009322853B2 (en) | Compositions and methods for promoting a relaxation state | |
| CN110787088A (en) | Basic composition for lip wrinkle fading and preparation method and application thereof | |
| KR101498609B1 (en) | Manufacturing method of bodylotion using herb and bodylotion made by that manufacturing method | |
| CN105581948A (en) | Skin surface lipid film repair type makeup removal paste and preparation method thereof | |
| CN106163617A (en) | The compositions comprising queen bee venom for skin | |
| JP2000063227A (en) | Agent for stimulating degradation of lipid and skin preparation for external use and for slimming body | |
| CN107412016A (en) | A kind of compound essential oil with whitening effect and preparation method thereof | |
| CN106943474A (en) | A kind of Chinese medicine compound prescription essential oil with dispeling scar effect and preparation method thereof | |
| CN116036176B (en) | Plant anti-drop compound and preparation method thereof | |
| CN110917105A (en) | Allergy-relieving cosmetic composition and preparation method thereof | |
| CN101695470B (en) | Composite for cosmetics, cosmetic product containing same and preparation method thereof | |
| JP2000063260A (en) | Lipid decomposition accelerator and skin preparation for external use for weight reduction | |
| CN105534813A (en) | Cosmetic composition with dark circle relieving effect and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180801 Address after: 510000 Guangzhou, Guangdong Baiyun District, man and town Xicheng Industrial Zone No. 9 Applicant after: Guangzhou hangmei Cosmetics Co. Ltd. Address before: 528000 2AP68 two, No. 82 Jinhua Road, Chancheng District, Foshan, Guangdong. Applicant before: FOSHAN QIANRU COSMETICS CO., LTD. |
|
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160706 |