CN105708759B - A kind of pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil and preparation method thereof - Google Patents

A kind of pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil and preparation method thereof Download PDF

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CN105708759B
CN105708759B CN201610091642.6A CN201610091642A CN105708759B CN 105708759 B CN105708759 B CN 105708759B CN 201610091642 A CN201610091642 A CN 201610091642A CN 105708759 B CN105708759 B CN 105708759B
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vitamin
skin
face
seed oil
extract
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戢小梅
陈法志
李秀丽
陈镇
郑承翔
谭庆
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Wuhan Academy of Agricultural Sciences
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Fruit Tree Research Institute Of Forestry Science Wuhan Academy Of Agricultural Science & Technology
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract

The invention discloses a kind of pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil and preparation method thereof, the face cream is by peony seed oil, small molecule saualane, excellent olive emulsifying wax, rose, vitamin E, vitamin B5, vitamin B3, biological polyoses glue, entirely imitate exocellular polysaccharide, glabridin, Turmeric P.E, Fructus Piperis extract, ginseng extract, Yilan hydrosol, deionized water, pentanediol, 1,3 butanediols and antiseptic composition.The present invention not only can effectively moisten face skin, and it is good with skin cell compatibility, permeability is strong, is easily utilized by facial percutaneous absorption, it can comprehensively provide face skin required various nutrition, damaged cell can be more repaired rapidly, recover skin of face cytoactive, smooth out wrinkles, delay facial aging, keep the persistently pale colour of skin, allow face reappears at an early age it is delicate moisten, resist face skin aging.

Description

A kind of pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil and preparation method thereof
Technical field
The invention belongs to daily cosmetics technical field, is related to a kind of anti-skin oxidative aging and suppresses what melanin was formed Composition, more particularly to a kind of pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil and preparation method thereof.
Background technology
Skin is the outermost tissue of human body, and wherein skin of face is that human body is most directly perceived again, most easily exposes, while is again The position of most easy aging.With the passing of the years, skin slowly aging, this process be concealment, it is progressive, be organism not The evitable natural law.With age, in human body moisture loss, support the elasticated net of skin to be broken, skin Follow the string with gloss, there is wrinkle, dry water shortage, pigment excess deposition etc..Oxidation is to cause the biggest threat of skin senescence One of, the free radical causes of senescence of D.Harman, it is believed that human senility is the free radical by being produced in cell normal metabolic processes Illeffects caused by, in skin cell tissue excessive free radical occur accumulation and with cell membrane lipid material send out Raw oxidation, causes the damage of cell membrane, so as to produce the oxidative phenomenas such as the intense darkness without light pool of complexion, water shortage drying.Therefore support One of important means of anti-aging is to remove free radical excessive in human body.
Tyrosinase is widely present in human body, is the key enzyme of B16 cell.Skin Bai Bubai, depends primarily upon black The ability of chromatophore synthesis of melanin.In the basal layer of epidermis iuntercellular of people, melanocyte is dispersed with, the tyrosine that it contains Oxidizing tyrosine can be passed through a series of metabolic process again, can finally generate melanin by enzyme into polysaccharide, centre.Melanin Generation is more, and skin is pitch-darker；Conversely, then skin is more pale.Therefore, it is effective reduction black to suppress tyrosinase activity A kind of approach of element generation.
Face cream is the most important step of basic skin care, and the active ingredient such as whitening and anti-aging in face cream being capable of more preferable quilt Percutaneous absorption.With the continuous improvement of modern life level, people increasingly pay attention to skin care, and the use of face cream is also increasingly Extensively, the requirement to product composition is also higher and higher.Current market sales of face cream species is various, wherein be no lack of anti-aging and Whitening product.However, it is noteworthy that on the one hand currently marketed face cream is mostly using mineral wax, Synthetic Oil, mineral Oil etc., while artificial color, spices are added, some add hormonal components to realize that skin-improving benefits are not stinted in a short time, beautiful White product heavy metals exceeding standard etc., not only these components cannot nourish skin, can also damage face skin, influence the new of face skin Old metabolism, brings various skin problems, and potential eutrophication is formed to body；On the other hand the skin-protection product occurred on the market at present Especially anti-aging product effect is single, can only moisturizing or smoothing wrinkle remove spot, cannot but reach moisturizing, moisturizing, prevention pigment at the same time Multiple-effect protective effect that is calm and reducing wrinkle.
The content of the invention
The defects of in order to overcome the prior art and deficiency, it is an object of the present invention to provide a kind of collection moisturizing, moisturizing, The composition of anti-oxidant, prevention pigmentation and the anti aging effect to uvioresistant, especially provides a kind of containing male Pure natural anti-oxidant whitening multiple-effect washing cream of red seed oil and preparation method thereof.
In order to achieve the object of the present invention, inventor is studied by a large number of experiments, is finally obtained and is contained peony seeds as follows The technical solution of the pure natural anti-oxidant whitening multiple-effect washing cream of oil：
A kind of all natural ingredients composition for delaying face skin aging, it is by peony seed oil, small molecule saualane, excellent olive Emulsifying wax, rose, vitamin E, vitamin B5, vitamin B3, biological polyoses glue, entirely imitate exocellular polysaccharide, glabridin, ginger Yellow extract, Fructus Piperis extract, ginseng extract, Yilan hydrosol, deionized water, pentanediol, 1,3 butanediols and antiseptic group Into.
Preferably, the above-mentioned all natural ingredients composition for delaying face skin aging, wherein each component is by weight Amount number meter composition be：
It is further preferred that the above-mentioned all natural ingredients composition for delaying face skin aging, wherein each group The composition point counted in parts by weight is：
Still further preferably, all natural ingredients composition of face skin aging is delayed as described above, it is face cream, and The antiseptic is carrot antiseptic.
In addition, the preparation side of the above-mentioned all natural ingredients composition face cream for delaying face skin aging provided by the present invention Method, it includes following steps：
(1) glabridin, Turmeric P.E, Fructus Piperis extract, the ginseng extract of recipe quantity are weighed, respectively with 1,3 fourth Glycol dissolves, spare；
(2) A, B totally 2 beakers are taken, peony seed oil, excellent olive emulsifying wax and the rose of recipe quantity are added in A beakers；
(3) Yilan hydrosol, deionized water, the vitamin B of recipe quantity are added in B beakers5And vitamin B3, stir to complete Fully dissolved；
(4) A beakers and B beakers are heated in a water bath, heated while stirring, until decorating film dissolving, temperature reach 80 Stop heating after DEG C, the solution in B beakers is poured into A beakers according to a small amount of multiple mode and is quickly stirred evenly；
(5) when the temperature of liquid to be mixed is down to 50 DEG C, the vitamin E, small molecule saualane, biology of recipe quantity are sequentially added Polysaccharide gum, glabridin solution, Fructus Piperis extract solution, Turmeric P.E solution, ginseng extract solution, imitate exocellular polysaccharide entirely And pentanediol, often add a kind of component and stir 1-3 minutes；
(6) antiseptic of recipe quantity is eventually adding, is stirred evenly.
It should be noted that delay the preparation side of all natural ingredients composition face cream of face skin aging as described above Method, excellent olive emulsifying wax therein are the excellent olive liquid crystal olive emulsifying wax of the celestial graceful production of France, English name OLDERM CRYSTALM O IST, INCI are sorbierite olive oleate, the hard ester group glucoside of spermaceti；The full effect exocellular polysaccharide is complete for France codif Imitate exocellular polysaccharide 4.0；The biological polyoses glue is releived agent for -2 rhamnose of biological polyoses glue of the celestial graceful production of France；Described Turmeric P.E is commercial product, and trade name is Sabiwhite, is produced by U.S. SABINSA, purity 95%Sabiwhite； The Fructus Piperis extract is commercial product, and trade name is Cosmoperine, is produced by U.S. SABINSA, purity >=98% 4 Hydrogen pipering；The Yilan hydrosol is commercially available Madagascar Yilan hydrosol, and Cananga odorata quintessence oil content is 0.025%.
Preferably, the preparation method of all natural ingredients composition face cream of face skin aging is delayed as described above, wherein Ginseng extract be made as follows：Using ginseng pulverate as raw material, using butanediol and water by after isometric mixing as carrying Take solvent, the extraction of room temperature lucifuge, extraction time 30-60d is filtered, and filter vacuum concentrates to obtain the final product.
Found according to antioxygenic property experimental study, the sample 1 at the same time containing peony seed oil and ginseng extract Inoxidizability is significantly higher than only addition ginseng extract and does not add the sample 2 of peony seed oil, and is significantly higher than only addition tree peony Seed oil does not add the sample 3 of ginseng extract, and peony seed oil and ginseng extract are used in combination this explanation according to a certain percentage Have the function that skin histology excessive free radicals are removed in collaboration in skin care item.Therefore, present invention also offers two kinds of specific groups New opplication associated with point, i.e.,：Peony seed oil is preparing the skin care item for removing excessive free radicals in skin histology with ginseng extract In application；Or peony seed oil and application of the ginseng extract in inoxidizability skin care item are prepared.It is further preferred that institute The skin care item stated are face cream.
Compared with prior art, pure natural composition face cream of the invention has following beneficial technique effect：
(1) have whitening, moisturizing, it is anti-oxidant, lighten the stain, reduce wrinkle, antibacterial anti-inflammatory, to uvioresistant and retaining surface Portion's skin, which persistently moistens, waits multi-efficiency, not only can effectively moisten face skin, and, infiltration good with skin cell compatibility Property is strong, is easily utilized by facial percutaneous absorption, can comprehensively provide face skin required various nutrition, can more repaired rapidly Damaged cell, recovers skin of face cytoactive, and smooth out wrinkles delay facial aging, keep the persistently pale colour of skin, allows face Reappear delicate moist, confrontation face skin aging at an early age.
(2) face skin occurs under the serious water shortage state of dry decortication in the winter time, if gently apply last layer contain it is male The pure natural anti-oxidant whitening multiple-effect washing cream of red seed oil, and gently massaged, it just can intimately merge with face skin, ooze rapidly Saturating skin and protective film can be formed in face, allow moisture veritably to stay on skin, away from because contact wind, dirt, ultraviolet and The coarse decortication and lost its bounce that the reason for remaining stimulation of color make-up and internal water, vitamin etc. lack occurs are caused to skin Puzzlement, make face skin recover elastic force, compact He Shuirun.
(3) composition saves effective active composition well, can supplement the required nutrient of face skin, its master Function is wanted to be to protect and repair, for suppressing facial melanin is formationed, delaying skin aging, moisturizing, reducing wrinkle, compact carefully Tender and nutrition etc. can be played the role of good, accurately act on face skin cell, permeability is strong and is easily absorbed and used, rich Containing multiple active ingredient, effectively active cell it can be metabolized, nourish skin, repair damaged cell, smooth years trace, desalination color Spot, and lasting stability effect can be kept.
(4) can face skin surface formed one layer of anti-oxidation protection film simultaneously can fully penetrated to skin depths imparting flesh Skin vigor；It with the addition of with heigh antioxidation and alimentary peony seed oil and ginseng extract；It with the addition of at the same time with height Spend moist type, humidity-preserving type and infiltrative natural small molecule saualane component；Also added with nourish skin, activating cell and The rose of natural water lock effect.
(5) after smearing face skin for a period of time, the pale tender skin of water as baby is presented in face, and can keep persistently taste Profit, tender skin highlight the whitening colour of skin.Because which are added naturally take off black whitening material glabridin, Turmeric P.E and pepper Extract, can effectively suppress the activity of the key enzyme tyrosinase of dermal melanin synthesis, so that prevent melanin from being formed, with The affinity of skin is extremely strong, face skin can be played and moisten tender white effect for a long time.
(6) composition uses pure natural antibacterial component, reduces skin stimulation and mistake that addition artificial preservative is brought Quick symptom, the pentanediol of addition are the natural moisture preserving agent of excellent performance and have anti-corrosion function, and the carrot antiseptic of addition is recklessly The filtrate of radish root tunning, has very strong sterilization sterilization functions, is all natural anticorrosion component, non-stimulated to skin.
(7) composition face cream forms for a variety of natural, green, safe components compoundings, have tender skin moisturizing, Whitening, spot, It is anti-oxidant, nontoxic, resist the characteristics of ultraviolet etc., the pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil both may be used Colonization when for face skin drying, pigment deposition, skin jaundice, skin darkening, wrinkle intensification and following the string, It as the anti-aging product for preventing face skin aging, can will become the development trend of facial-care product, have wide Market prospects and economic value.
Embodiment
It is the specific embodiment of the present invention below, technical scheme is done and is further described, but it is of the invention Protection domain be not limited to these embodiments.It is every to be included in this hair without departing substantially from the change of present inventive concept or equivalent substitute Within bright protection domain.
The preparation of embodiment 1-3 face creams
Formula is shown in Table 1：
The formula of 1 face cream composition of table
It should be noted that excellent olive liquid crystal olive emulsifying wax of the excellent olive emulsifying wax for the celestial graceful production of France, English name OLDERM CRYSTALM O IST, INCI are sorbierite olive oleate, the hard ester group glucoside of spermaceti；The rose is pure It is 0.05% to reveal for commercially available Bulgarian organic rose hydrosol, Rosa Damascana content；The full effect exocellular polysaccharide is France Codif imitates exocellular polysaccharide 4.0 entirely；The biological polyoses glue is releived for -2 rhamnose of biological polyoses glue of the celestial graceful production of France Agent；The Turmeric P.E is commercial product, and trade name is Sabiwhite, is produced by U.S. SABINSA, purity 95% Sabiwhite；The Fructus Piperis extract is commercial product, and trade name is Cosmoperine, is produced by U.S. SABINSA, pure Spend >=98% tetrahydrochysene pipering；The Yilan hydrosol is commercially available Madagascar Yilan hydrosol, and Cananga odorata quintessence oil content is 0.025%.
The preparing process of above-mentioned formula is as follows：
(1) preparation of ginseng extract
Take ginseng 15g → cleaning → crushing → 100ml butanediols+100ml distillation flooding (solid-liquid ratios 3:20, room temperature is kept away Light extracts, and extraction time 45d, preceding 7d is rocked often to be shaken up) → filtering vacuum concentration → ginseng extract finished product.
(2) solution is prepared
A, glabridin (90%Glabridin) solution is prepared
Glabridin powder (production of SABINSA companies of the U.S.) 0.3g accurately is weighed, with 1,3 butanediol with 1:9 mass ratio Dissolving, it is spare to be configured to alcoholic solution；
B, Turmeric P.E solution is prepared
It is accurate to weigh Turmeric P.E (SABINSA companies of the U.S. produce, trade name SabiWhite, purity 95%) 0.3g, With 1,3 butanediols with 1:8 mass ratio dissolving, pH value are controlled in 6.5-7, and it is spare to be configured to alcoholic solution；
C, Fructus Piperis extract solution is prepared
It is accurate to weigh Fructus Piperis extract (SABINSA companies of the U.S. produce, trade name Cosmoperine, purity 95%) respectively 0.3g, with 1,3 butanediol with 1:9 mass ratio dissolving, it is spare to be configured to alcoholic solution；
D, ginseng extract solution is prepared
Ginseng extract 0.3g accurately is weighed, is dissolved with the 1 of surplus, 3 butanediol, it is spare to be configured to alcoholic solution.
(3) deionized water processing procedure：
1. filter impurities in water；
2. high pressure passes through reverse osmosis membrane；
3. ultraviolet-sterilization；
4. carry out ion exchange process maximum resistance rate 18,000,000.
(4) take 2 clean beakers of A, B stand-by, added in A beakers the peony seed oil of recipe quantity, excellent olive emulsifying wax and Rose；
(5) Yilan hydrosol, deionized water, vitamin B5 and the vitamin B3 of recipe quantity are added in B beakers, is stirred to complete Fully dissolved；
(6) beaker A and beaker B are placed on constant temperature water proof on electromagnetic oven to heat, heated while stirring, until decorating film is molten Solution, temperature immediately lift down beaker A, B after reaching 80 DEG C, and the aqua in B beakers is poured into burning according to a small amount of multiple method Quickly stirred evenly in cup A, approximate time 30 minutes or so；
(7) when the temperature of mixture drops to 50 DEG C, vitamin E, small molecule saualane, the biology of recipe quantity are added according to this Polysaccharide gum, glabridin, Fructus Piperis extract, Turmeric P.E, ginseng extract, full effect exocellular polysaccharide and pentanediol, often add A kind of additive stirs 2 minutes；
(8) the carrot antiseptic of recipe quantity is eventually adding, sterilization filling is stirred evenly and both may be used；
(9) preserved under the face cream sealing room temperature that Packs sterilized installs, the term of validity 12 months.
The pure natural anti-oxidant whitening multiple-effect washing cream containing peony seed oil prepared using above-mentioned formula and technique is had such as Lower effect：
(1) full nutrition face skin, repairs damaged cell, recovers skin of face cytoactive, keeps persistently pale The colour of skin, allow face reappear at an early age it is delicate moisten, resist face skin aging；
(2) infiltration face skin and protective film can be formed rapidly, nourishes face skin, face skin is recovered elastic force, tight Cause and water moistens；
(3) effectively prevention stops that melanin is formed, and prevents pigementation；
(4) cytothesis is effectively facilitated, reduces wrinkle, delaying skin aging；
(5) face skin allergy caused by wind, dirt, color make-up etc. is effectively prevented；
(6) effectively prevent ultraviolet from being injured caused by skin, there is sun-proof function.
4 face cream moisture-absorbing moisture-keeping performance research of embodiment
Respectively take 6 parts to be divided into 2 groups embodiment 1-3, glycerine, hyaluronic acid, each sample is mounted in the table of a diameter of 4cm respectively On the ware of face, it is precisely weighed after first group of sample to be put into the drier processing 24h for filling silica gel for moisture absorption under high humidity Rate measures.Equally second group of sample is put into the vacuum desiccator that vacuum is -0.1MPa after drying process 24h and is precisely weighed Measured for hydroscopicity under low-moisture conditions.Relative humidity (RH) is 81% saturated ammonium sulfate aqueous solution under room temperature (25 DEG C) Drier is super-humid conditions, and the drier that relative humidity (RH) is 43% is low humidity conditions.Sample is accurate after the moisture absorption of 24h Weigh each sample mass, by before and after moisture absorption sample it is of poor quality, obtain hydroscopicity according to the following formula：
Hydroscopicity=(Mn-M0)/M0× 100% formula (1)
In formula (1)：M0For quality before sample moisture absorption, Mn is quality after moisture absorption 24h.When the moisture of absorption, to reach saturation follow-up It is continuous to place 24h, each sample mass is accurately weighed, by of poor quality before and after sample, obtains moisturizing rate according to the following formula：
Moisturizing rate=Hn/H0× 100% formula (2)
In formula (2)：HnContain water quality, H for sample0Contain water quality to place sample after 24h
Sample moisture-absorbing moisture-keeping type result of the test is shown in Table 2.
2 sample moisture absorbability and moisture retentivity result of the test of table
The hygroscopicity that can be seen that embodiment 1-3 under high humidity from the test statistics result of table 2 does not protrude, but Moistening effect is apparently higher than glycerine and hyaluronic acid；Under low humidity conditions, embodiment 1-3 moisture absorptions, moisture retention are very prominent, excellent In glycerine and hyaluronic acid, especially with good hygroscopicity, and moisture-absorbing moisture-keeping effect stability.Therefore it is more dry for winter Dry weather, embodiment face cream can play good moistening effect, be preferable preserving moisture and protecting skin face cream.
5 whitening performance test of embodiment
Experiment sets 3 samples, and sample 1,2 is 2 face cream of embodiment 1 and embodiment, sample 3 (positive controls) For vitamin C, the aqueous solution of 50 μ g/L is configured to respectively, takes 2ml test samples (blank sample is with phosphate buffer replacement) and 1ml The mixed liquor of tyrosinase (100u), 37 DEG C of incubation 10min, adds 0.003molL-1Dopa reaction liquid 1ml, continues at 37 DEG C 2min is incubated, absorbance, each 3 repetitions of sample are measured at 475nm, inhibitory activity against tyrosinase is calculated as follows：
Inhibiting rate={ [(A-B)-(C-D)]/(A-B) } × 100%
Wherein, A is absorbance of the mixed liquor at 475nm for not being loaded product and adding tyrosinase；B is is not loaded product and not Add absorbance of the mixed liquor of tyrosinase at 475nm；C is suction of the mixed liquor of sample-adding product and tyrosinase at 475nm Luminosity；D does not add absorbance of the mixed liquor of tyrosinase at 475nm for sample-adding product.Inhibiting rate shows more greatly whitening capability more By force.Result of the test is shown in Table 3.
3 sample whitening performance test results of table
Embodiment 1 and embodiment 2 are can be seen that when concentration is 50 μ g/L from the test statistics result of table 3, to network junket ammonia The inhibiting rate of sour enzyme is respectively 47.86% and 43.90%, it can be seen that, embodiment 1 and embodiment 2 are respectively provided with stronger junket ammonia Sour enzyme inhibition, and inhibiting rate is above positive control VC, shows preferable whitening potentiality.
6 antioxygenic property of embodiment is tested
Experiment sets 3 samples, and sample 1 is 1 face cream of embodiment, and sample 2 is to replace peony seed oil (other with oil-soluble VE Component is with embodiment 1), sample 3 be that ginseng extract (other components are with embodiment 1) replaced with deionized water, with 95% second Alcohol compound concentration is 0.04mg/ml DPPH solution.1ml sample solutions and 3ml DPPH solution are pipetted in tool plug test tube, fully After mixing, lucifuge stands 30min after measure absorbance A under 517nm at room temperature1.Sample solution is replaced to make with 1ml ethanol empty White measure absorbance A0, the absorbance A with 3ml ethanol instead of DPPH solution determination sample solution2.DPPH is calculated according to the following formula certainly By the clearance rate of base (experimental result is shown in Table 4)：
The clearance rate of DPPH free radicals=(1- (A1-A2)/A0) × 100%
Clearance rate of 4 each sample of table to DPPH free radicals
DPPH is a kind of very stable free radical, this is because the Resonance Stabilization action of its phenyl ring and spatial obstacle effect make Being in lonely pair on the nitrogen-atoms in center of electronics cannot be paired.DPPH is dark purple in alcoholic solution, when there is free radical scavenger In the presence of, the lone pair electrons in DPPH on nitrogen are paired and so that solution colour shoal, the suction at maximum absorption wavelength 517nm Luminosity diminishes, therefore absorbance is smaller, and clearance rate is bigger, shows that the oxidation resistance of scavenger is stronger.From the experiment of table 4 Statistical result can be seen that the clearance rate and sample 2,3 significant difference of sample to DPPH free radicals of 1 solution of sample, sample 1 Clearance rate is up to 83.19%, shows the clearance rate of stronger oxidation resistance, sample 2 and sample 3 to DPPH free radicals Difference is not notable, its clearance rate to DPPH free radicals is respectively 32.65% and 45.56%.From the point of view of the component of 3 samples, Sample 1 contains peony seed oil and ginseng extract, and sample 2 is free of peony seed oil, remaining component is free of ginseng with sample 1, sample 3 Extract, remaining component are not difficult to find out, at the same time containing peony seed oil and ginseng with sample 1 from the clearance rate to DPPH free radicals The inoxidizability of the sample 1 of extract is significantly higher than only addition ginseng extract and does not add the sample 2 of peony seed oil and only add Peony seed oil does not add the sample 3 of ginseng extract, and the inoxidizability of sample 1 is noticeably greater than sample 2 and sample 3, this explanation Peony seed oil and ginseng extract are used in combination according to a certain percentage, and there is collaboration to remove skin histology excess in skin care item The effect of free radical.

Claims (6)

1. a kind of all natural ingredients composition for delaying face skin aging, it is by peony seed oil, small molecule saualane, excellent olive breast Change wax, rose, vitamin E, vitamin B5, vitamin B3, biological polyoses glue, entirely imitate exocellular polysaccharide, glabridin, turmeric Extract, Fructus Piperis extract, ginseng extract, Yilan hydrosol, deionized water, pentanediol, 1,3-BDO and antiseptic composition, The composition that each component is counted in parts by weight is：
Peony seed oil 9-11
Small molecule saualane 4-6
Excellent olive emulsifying wax 4-6
Rose 0.5-1.5
Vitamin E 1-3
Vitamin B5 2-4
Vitamin B3 1-3
Biological polyoses glue 2-4
Full effect exocellular polysaccharide 0.5-1.5
Glabridin 0.1-0.3
Turmeric P.E 0.05-0.15
Fructus Piperis extract 0.1-0.2
Ginseng extract 0.1-0.2
Yilan hydrosol 30-50
Deionized water 20-40
Pentanediol 1-3
1,3 butylene glycol 3-8
Antiseptic 1-3.
2. delay all natural ingredients composition of face skin aging according to claim 1, it is characterised in that each group The composition point counted in parts by weight is：
Peony seed oil 10
Small molecule saualane 5
Excellent olive emulsifying wax 5
Rose 1
Vitamin E 2
Vitamin B5 3
Vitamin B3 2
Biological polyoses glue 3
Full effect exocellular polysaccharide 1
Glabridin 0.2
Turmeric P.E 0.1
Fructus Piperis extract 0.15
Ginseng extract 0.15
Yilan hydrosol 40
Deionized water 30
Pentanediol 2
1,3 butylene glycol 5.45
Antiseptic 2.
3. all natural ingredients composition according to claim 1 or claim 2 for delaying face skin aging, it is characterised in that described Antiseptic be carrot antiseptic.
4. all natural ingredients composition according to claim 1 or claim 2 for delaying face skin aging, it is characterised in that described Composition be face cream.
5. a kind of preparation method for all natural ingredients composition for delaying face skin aging according to claim 4, it is special Sign is that this method comprises the following steps：
（1）Glabridin, Turmeric P.E, Fructus Piperis extract, the ginseng extract of recipe quantity are weighed, uses 1,3-BDO respectively Dissolving, it is spare；
（2）A, B, C totally 3 beakers are taken, peony seed oil, excellent olive emulsifying wax and the rose of recipe quantity are added in A beakers；
（3）Yilan hydrosol, deionized water, the vitamin B of recipe quantity are added in B beakers5And vitamin B3, stir to completely molten Solution；
（4）A beakers and B beakers are heated in a water bath, heated while stirring, until after decorating film dissolving, temperature reach 80 DEG C Stop heating, the solution in B beakers is poured into A beakers according to a small amount of multiple mode and is quickly stirred evenly；
（5）When the temperature of liquid to be mixed is down to 50 DEG C, the vitamin E, small molecule saualane, biological polyoses of recipe quantity are sequentially added Glue, glabridin solution, Fructus Piperis extract solution, Turmeric P.E solution, ginseng extract solution, full effect exocellular polysaccharide and penta Glycol, often adds a kind of component and stirs 1-3 minutes；
（6）The antiseptic of recipe quantity is eventually adding, is stirred evenly.
6. delaying the preparation method of all natural ingredients composition of face skin aging according to claim 5, its feature exists In the ginseng extract is made as follows：Using ginseng pulverate as raw material, after butanediol and water are pressed isometric mixing Concentrated as Extraction solvent, the extraction of room temperature lucifuge, extraction time 30-60d, filtering, filter vacuum to obtain the final product.
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CN104971016A (en) * 2015-07-31 2015-10-14 桂林市宏旭生物科技有限公司 Firming and repairing fair mask product and preparation method thereof
CN105078875A (en) * 2015-09-06 2015-11-25 菏泽瑞璞牡丹产业科技发展有限公司 Peony extract-containing cosmetic and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971016A (en) * 2015-07-31 2015-10-14 桂林市宏旭生物科技有限公司 Firming and repairing fair mask product and preparation method thereof
CN105078875A (en) * 2015-09-06 2015-11-25 菏泽瑞璞牡丹产业科技发展有限公司 Peony extract-containing cosmetic and preparation method thereof

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Patentee before: FRUIT TREE RESEARCH INSTITUTE OF FORESTRY SCIENCE, WUHAN ACADEMY OF AGRICULTURAL SCIENCE & TECHNOLOGY