CN105687087A

CN105687087A - Preparation method of skin-tightening and freckle-removing biological dressing

Info

Publication number: CN105687087A
Application number: CN201610140651.XA
Authority: CN
Inventors: 李苏扬; 李文遐; 徐勤霞
Original assignee: Suzhou Bec Biological Technology Co Ltd
Current assignee: Suzhou Bec Biological Technology Co Ltd
Priority date: 2016-03-14
Filing date: 2016-03-14
Publication date: 2016-06-22

Abstract

The invention discloses a preparation method of a skin-tightening and freckle-removing biological dressing. According to the preparation method, raw materials are weighed, put in a reactor and subjected to ultrasonic dispersion at a high speed; the dispersed mixture is poured into a film preparation mold, scraped to be flat and sufficiently dried, the mold is removed, and a drug storage layer is prepared; finally, the prepared drug storage layer and base cloth are bonded and composited through an adhesive, and a bonding composite is punched by a dense needling micropore forming machine; the punched dense composite is cut into a required shape, sealed and sterilized. The biological dressing prepared with the method adopts a traditional Chinese medicine formula, has small irritation, doesn't have toxic or side effects and has good biocompatibility, and relapse is not easily caused. Through reasonable matching, skin regeneration organs are reserved and activated to the greatest extent, the skin condition is relieved, and skin tightening, freckle removing and wrinkling smoothing are promoted.

Description

A kind of preparation method of Firm speckle biological dressing

Technical field

The invention belongs to medical bio field of new, the preparation method relating to a kind of Firm speckle biological dressing。

Technical background

Everybody has a love of beauty, and along with improving constantly of people's living standard, beautiful pursuit is also improved constantly by people, for most of women, is intended to change the appearance of oneself and have the pale colour of skin。But, for women, with advancing age, the metabolism of health slows down, and melanin cannot normally be mediated, and at horny layer formation of deposits speckle, by and form chloasma, black speck and mottle；Life anxiety, works and rests irregular, and various environmental pollution, causes that self-resistance declines, and endocrine disturbance makes interior free yl activate, and increases melanin abnormal secretion。With advancing age, women wrinkle also gets more and more simultaneously, oneself more seems young to allow, and many women are more compacted compact for skin, adopt the mode playing hormone pin, and health is had bigger side effect by this mode, it is easy to cause endocrine disturbance。But current beauty industry is extremely complex, both advantageous and disadvantageous, many times, all can hear that some thus result in some cureless final results because of the former of cosmetics。At present, the method commonly used in beauty industry includes therapeutic method of surgery, drug treatment and outer coating method。But operative treatment is not appropriate for for many patients, has a big risk；Pharmacotherapy, including oral medicine and medicine for external use, also ubiquity effect not significantly shortcoming。And outer coating method is simple to operation and the injury of patient is minimum, therefore, increasing consumer pays close attention to outer coating method。

Biological dressing is the Novel wound reparation and protection material that grow up in repair in trauma " moistening healing " theoretical basis proposed such as Winter。Compared with traditional dressing, biological dressing has reduction and infects, improves wound healing quality, alleviate the misery of patient and facilitate the advantages such as medical personnel's operation, therefore obtains the favor of people。But also little for the dressing of Firm speckle dispelling on the market at present, it is almost blank。In view of this, it is necessary to a kind of skin problem dressing that effectively can effectively solve cutis laxa and pigmentation initiation is provided。

Summary of the invention

Present invention aims to the deficiencies in the prior art, it is provided that the preparation method of a kind of Firm speckle biological dressing。

It is an object of the invention to be achieved through the following technical solutions: the preparation method of a kind of Firm speckle biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 30-40 part, chitosan lactate 12-20 part, pectin 3-10 part, alginate 3-12 part, Bombyx Batryticatus powder 10-20 part, motherwort powder 10-20 part, Radix Rhodiolae powder 10-20 part, Mel 10-20 part, Sandalwood powder 5-8 part, emulsifying agent 3-10 part and water 30-40 part are placed in reactor, ultrasonic high speed dispersion, ultrasonic frequency is 20-40KHz, rate of dispersion 5000-5400r/min, jitter time is 30-60min；Then the mixture after dispersion is poured on masking mould, strike off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing。

Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane。

Described binding agent is pressure sensitive adhesive。

Described alginate is potassium alginate, sodium alginate or calcium alginate。

Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate。

Biological dressing prepared by the method by the present invention that the method have the advantages that adopts Chinese medicine formula, and zest is little, has no side effect, and not easily recurs, and has good biocompatibility。By rational compatibility, retain to greatest extent and activate skin regeneration organ, improving skin, promoting cell turnover, increasing skin collagen yield, thus promoting that skin is tight, speckle, desalination wrinkle。The effects such as this formula is reasonable, science, and cicatrix not only has heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, and at the anti-wrinkle of skin, striae gravidarum, crows-feet, mottle, cicatrix initial therapy excellent。

Detailed description of the invention

Embodiment 1

A kind of preparation method of Firm speckle biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 30 parts, chitosan lactate 12 parts, pectin 3 parts, alginate 3 parts, 10 parts of Bombyx Batryticatus powder, motherwort powder 10 parts, 10 parts of Radix Rhodiolae powder, Mel 10 parts, Sandalwood powder 5 parts, emulsifying agent 3 parts and 30 parts of water and be placed in reactor, ultrasonic high speed dispersion, ultrasonic frequency is 20-40KHz, rate of dispersion 5000-5400r/min, jitter time is 30-60min；Then the mixture after dispersion is poured on masking mould, strike off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing。

Described binding agent is pressure sensitive adhesive。

Embodiment 2

A kind of preparation method of Firm speckle biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 40 parts, chitosan lactate 20 parts, pectin 10 parts, alginate 12 parts, 20 parts of Bombyx Batryticatus powder, motherwort powder 20 parts, 20 parts of Radix Rhodiolae powder, Mel 20 parts, Sandalwood powder 8 parts, emulsifying agent 10 parts and 40 parts of water and be placed in reactor, ultrasonic high speed dispersion, ultrasonic frequency is 20-40KHz, rate of dispersion 5000-5400r/min, jitter time is 30-60min；Then the mixture after dispersion is poured on masking mould, strike off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing。

Described binding agent is pressure sensitive adhesive。

Embodiment 3

A kind of preparation method of Firm speckle biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 35 parts, chitosan lactate 16 parts, pectin 6 parts, alginate 8 parts, 15 parts of Bombyx Batryticatus powder, motherwort powder 15 parts, 15 parts of Radix Rhodiolae powder, Mel 15 parts, Sandalwood powder 6 parts, emulsifying agent 6 parts and 35 parts of water and be placed in reactor, ultrasonic high speed dispersion, ultrasonic frequency is 20-40KHz, rate of dispersion 5000-5400r/min, jitter time is 30-60min；Then the mixture after dispersion is poured on masking mould, strike off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing。

Described binding agent is pressure sensitive adhesive。

Claims

1. the preparation method of a Firm speckle biological dressing, it is characterized in that this preparation method comprises the following steps: by weight, weigh chitosan 30-40 part, chitosan lactate 12-20 part, pectin 3-10 part, alginate 3-12 part, Bombyx Batryticatus powder 10-20 part, motherwort powder 10-20 part, Radix Rhodiolae powder 10-20 part, Mel 10-20 part, Sandalwood powder 5-8 part, emulsifying agent 3-10 part and water 30-40 part and be placed in reactor, ultrasonic high speed dispersion, ultrasonic frequency is 20-40KHz, rate of dispersion 5000-5400r/min, jitter time is 30-60min；Then the mixture after dispersion is poured on masking mould, strike off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing。

2. the preparation method of a kind of Firm speckle biological dressing according to claim 1, it is characterised in that: described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane。

3. the preparation method of a kind of Firm speckle biological dressing according to claim 1, it is characterised in that: described binding agent is pressure sensitive adhesive。

4. the preparation method of a kind of Firm speckle biological dressing according to claim 1, it is characterised in that: described alginate is potassium alginate, sodium alginate or calcium alginate。

5. the preparation method of a kind of Firm speckle biological dressing according to claim 1, it is characterised in that: described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate。