CN101757347B - Clinopodium polycephalum band-aid and preparation method thereof - Google Patents
Clinopodium polycephalum band-aid and preparation method thereof Download PDFInfo
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- CN101757347B CN101757347B CN2010101157789A CN201010115778A CN101757347B CN 101757347 B CN101757347 B CN 101757347B CN 2010101157789 A CN2010101157789 A CN 2010101157789A CN 201010115778 A CN201010115778 A CN 201010115778A CN 101757347 B CN101757347 B CN 101757347B
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- water absorption
- absorption cushion
- band
- aid
- clinopodium polycephalum
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Abstract
The invention discloses a clinopodium polycephalum band-aid and is characterized in that the water sucking liner of the band-aid is arranged as medicine-containing water sucking liner, the medicine in the medicine-containing water sucking liner is composed of 10-50 parts of clinopodium polycephalum extract and 2-10 parts of sangusis draconis in parts by weight, wherein total glycoside content of clinopodium polycephalum extract in weight percent is not less than 80%. The invention has the convenience of existing band-aids, and multiple functions such as quick hemostasis, wound antiphlogosis and healing promotion.
Description
Technical field
The present invention relates to a kind of can quick-acting haemostatic powder and wound had antiinflammatory and promote the adhesive bandage of healing effect.
Background technology
People in daily life, because of carelessness because of cutter, cut or other sharp weapon injure health, stay minor cut or wound, for the hemostasis of the acute minor cut or wound of this class, antiinflammatory or more wound use adhesive bandage usually.Present existing adhesive bandage mainly is to reach hemostasia effect by physics compressing, treats, and is applicable to that otch is neat, cleaning, table is shallow, wound is less and the incised wound that need not sew up, scratch or stab.Because of it carries conveniently, easy to use, be fit to the fast pace of current society and be subjected to the favor of consumer, thereby become the hygienic material of family, hospital, clinic first aid indispensability.
Though adhesive bandage commonly used has at present been emphasized water absorption, promptly inhale and go oozing of blood and wound sepage, on structural design, emphasized the convenience that client uses, but owing to there is not drug effect, the effect that does not possess anti-inflammation, thereby unfavorable to the healing of wound has strengthened the risk of traumatic infection.If cross use of a specified duration it, the outer field adhesive plaster air proof of adhesive bandage just can make skin whitening, the deliquescing of wound and wound circumference, causes secondary infection.
Summary of the invention
The present invention is for avoiding above-mentioned existing in prior technology weak point, a kind of clinopodium polycephalum band-aid and preparation method thereof is provided, can continue to use the convenience of existing adhesive bandage, the multiple action that can also reach quick-acting haemostatic powder and wound is had antiinflammatory and promotes to heal.
Technical solution problem of the present invention adopts following technical scheme
The characteristics of clinopodium polycephalum band-aid of the present invention are that the water absorption cushion that adhesive bandage is set is the pastille water absorption cushion, and the medicine in the described pastille water absorption cushion is to be made of Herba Clinopodii extract and Sanguis Draxonis, and wherein, Herba Clinopodii extract by weight is 10-50 part; Sanguis Draxonis is 2-10 part; The described Herba Clinopodii extract total glycosides amount that contains by weight percentage is not less than 80%.
The characteristics of the preparation method of clinopodium polycephalum band-aid of the present invention are:
The Sanguis Draxonis micropowder of getting Herba Clinopodii extract and crossing the 100-160 mesh sieve is 12-60g altogether, adds hydrophilic matrix 16～80g, and adding concentration of volume percent again and be 75% ethanol to total amount is 100-500ml, and mix homogeneously promptly gets medicinal liquid;
Soak into water absorption cushion with described medicinal liquid, water absorption cushion is dried naturally be the pastille water absorption cushion again;
Described pastille water absorption cushion is sticked on the strip medical proof fabric, and at the surface coverage medical plastic thin film of pastille water absorption cushion.
The characteristics of the preparation method of clinopodium polycephalum band-aid of the present invention also are:
Described hydrophilic matrix is to be made of carboxymethyl cellulose, gelatin, glycerol and micropowder silica gel.
The consumption of carboxymethyl cellulose, gelatin, glycerol and micropowder silica gel is respectively in the described hydrophilic matrix: 2-10g, 2-10g, 2-10g, 10-50g.
According to " record in the Chinese pharmacopoeia, Herba Clinopodii is clinical to be used for metrorrhagia, hematuria, epistaxis, gingival hemorrhage, wound hemorrhage and hysteromyoma hemorrhage etc. have hemostasis and antiinflammatory, bacteriostasis; Sanguis Draxonis cures mainly treating swelling and pain by traumatic injury, ecchymoma due to internal injury, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time; Can be used for malignant boil carbuncle, do not close up for a long time, incised wound is hemorrhage, and wound such as does not conform at disease.Among the present invention two medicines share show its hemostasis rapidly, the anti-inflammation analgesia, promote the comprehensive effect of wound quickly-healing.And, take natural drug and have no side effect, do not find anaphylaxis in the experiment.
Compared with the prior art, beneficial effect of the present invention is embodied in:
1, the present invention adds the natural Chinese medicine Herba Clinopodii extract and rare Chinese medicine Sanguis Draxonis powder is made the pastille adhesive bandage, is used for the conventional hemorrhage and postoperative wound of local wound, and is convenient to use.Wherein, the main effect of Herba Clinopodii show its can be directly to all kinds of wound hemostasis, promote blood coagulation, three aspects of vasoconstrictive indirectly; According to " China's book on Chinese herbal medicine " record, Herba Clinopodii medicated powder 1g or 0.5g spread on rabbit carotid artery, femoral artery otch, liver and hind leg skin, muscle cutting wound surface, are showing the shortening bleeding stopping period, and effect is better than YUNNAN BAIYAO; Sanguis Draxonis decapacitation hemostasis also has convergence absorption, antibacterial and anti-inflammation functions, can promote wound healing.Two medicines share hemostasis rapidly, anti-inflammation analgesia and promote the wound quickly-healing that good effect is arranged.
2, the product cost of adhesive bandage of the present invention is compared slightly height with adhesive bandage commonly used, but then cheap a lot of with the medicine for external use such as the Yunnan BAIYAO of similar effect.
3, preparation method of the present invention is simple, can be made into island shape adhesive bandage, has improved greatly to produce and has renderd a service, and has reduced production cost.
The specific embodiment
Get and detect qualified Herba Clinopodii extract 10 grams and Sanguis Draxonis powder 2 grams; Add hydrophilic matrix carboxymethyl cellulose 2g, gelatin 2g, glycerol 2g and micropowder silica gel 10g, adding concentration of volume percent again and be 75% ethanol to total amount is 100ml, and mix homogeneously promptly gets medicinal liquid; Soak into water absorption cushion with above-mentioned medicinal liquid, the water absorption rate that liner selects for use medical absorbent cotton and polypropylene fiber to form is not less than 150% high-quality liner, and size is 22 * 11mm, and thickness 5mm dries water absorption cushion naturally and is the pastille water absorption cushion; The pastille water absorption cushion is sticked on the strip medical proof fabric, and at the surface coverage medical plastic thin film of pastille water absorption cushion, cut into 1000 adhesive bandages after compound, packaging sterilizing.
Given the test agent: clinopodium polycephalum band-aid of the present invention
Control sample: commercially available common adhesive bandage goes
Experimental program: 10 of rabbit, be divided into two groups at random, 5 every group, carry out the part depilation respectively in carotid artery, femoral artery and both sides, back, paste to make things convenient for adhesive bandage.Be in and run away like a hare hair everywhere, make 1cm left and right sides otch, the degree of depth is advisable with broken and blood vessel, and with disconnected Sanguis Draxonis adhesive bandage, group is with commercially available common adhesive bandage in contrast for another group to one group of wound, and change once every day, observes a week continuously.
Experimental result: by statistics, three days complete healing rates of wound of treatment group reach 50%, the complete healing rate 10% of matched group wound after the week; Five days complete healing rates of wound of treatment group reach 80%, the complete healing rate 50% of matched group wound; After one week, treatment is formed a mouthful complete healing rate and is reached 100%, and the complete healing rate of matched group wound has only 80%.
The result judges: significantly better than matched group, both have significant difference to disconnected Sanguis Draxonis adhesive bandage to wound healing.
In concrete the enforcement, also can be listed for each drug dose by following table 1:
| Group | Herba Clinopodii extract | Sanguis Draxonis powder | Carboxymethyl cellulose | Gelatin | Glycerol | Micropowder silica gel |
| 1 | 10g | 2g | 2g | 2g | 2g | 10g |
| 2 | 20g | 4g | 4g | 4g | 4g | 20g |
| 3 | 30g | 6g | 6g | 6g | 6g | 30g |
| 4 | 40g | 8g | 8g | 8g | 8g | 40g |
| 5 | 50g | 10g | 10g | 10g | 10g | 50g |
In the above-mentioned tabulation, each group is formed according to a certain ratio, and the wherein adding of hydrophilic matrix carboxymethyl cellulose, gelatin, glycerol and micropowder silica gel can promote medicine uniform distribution in solution; Ethanol is volatile, can shorten flash-off time.
Claims (4)
1. clinopodium polycephalum band-aid, the water absorption cushion that it is characterized in that being provided with adhesive bandage is the pastille water absorption cushion, and the medicine in the described pastille water absorption cushion is to be made of Herba Clinopodii extract and Sanguis Draxonis, and wherein, Herba Clinopodii extract by weight is 10-50 part; Sanguis Draxonis is 2-10 part; The described Herba Clinopodii extract total glycosides amount that contains by weight percentage is not less than 80%.
2. the preparation method of the described clinopodium polycephalum band-aid of claim 1 is characterized in that:
The Sanguis Draxonis micropowder of getting Herba Clinopodii extract and crossing the 100-160 mesh sieve is 12-60g altogether, adds hydrophilic matrix 16～80g, and adding concentration of volume percent again and be 75% ethanol to total amount is 100-500ml, and mix homogeneously promptly gets medicinal liquid;
Soak into water absorption cushion with described medicinal liquid, water absorption cushion is dried naturally be the pastille water absorption cushion again;
Described pastille water absorption cushion is sticked on the strip medical proof fabric, and at the surface coverage medical plastic thin film of pastille water absorption cushion.
3. the preparation method of clinopodium polycephalum band-aid according to claim 2 is characterized in that described hydrophilic matrix is to be made of carboxymethyl cellulose, gelatin, glycerol and micropowder silica gel.
4. the preparation method of clinopodium polycephalum band-aid according to claim 3 is characterized in that the consumption of carboxymethyl cellulose, gelatin, glycerol and micropowder silica gel in the described hydrophilic matrix is respectively: 2-10g, 2-10g, 2-10g, 10-50g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101157789A CN101757347B (en) | 2010-03-01 | 2010-03-01 | Clinopodium polycephalum band-aid and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101157789A CN101757347B (en) | 2010-03-01 | 2010-03-01 | Clinopodium polycephalum band-aid and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101757347A CN101757347A (en) | 2010-06-30 |
| CN101757347B true CN101757347B (en) | 2011-04-06 |
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| CN2010101157789A Expired - Fee Related CN101757347B (en) | 2010-03-01 | 2010-03-01 | Clinopodium polycephalum band-aid and preparation method thereof |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102273380B (en) * | 2011-06-07 | 2012-11-21 | 汪盛明 | Grafting paste and preparation method thereof |
| CN104107108B (en) * | 2014-06-23 | 2016-06-08 | 江美珍 | A kind of bandage utilizing Manyhead Clinopodium Herb sterilization |
| CN104288829B (en) * | 2014-09-29 | 2016-02-24 | 江苏奇力康皮肤药业有限公司 | A kind of adhesive bandage and preparation method thereof |
| CN108853561B (en) * | 2018-06-20 | 2021-08-06 | 山东辰星医疗科技有限公司 | Medical band-aid capable of rapidly stopping bleeding and relieving pain and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1453008A (en) * | 2002-04-22 | 2003-11-05 | 高其民 | Flexible fabric bandage with Chinese medicine and its prepn |
| CN101353279A (en) * | 2008-08-30 | 2009-01-28 | 丛秀云 | Medicine for injury, preparation thereof and preparation of woundplaster of the medicine for injury |
-
2010
- 2010-03-01 CN CN2010101157789A patent/CN101757347B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1453008A (en) * | 2002-04-22 | 2003-11-05 | 高其民 | Flexible fabric bandage with Chinese medicine and its prepn |
| CN101353279A (en) * | 2008-08-30 | 2009-01-28 | 丛秀云 | Medicine for injury, preparation thereof and preparation of woundplaster of the medicine for injury |
Non-Patent Citations (1)
| Title |
|---|
| 汪莉等.断血流的生药学研究概况.《安徽中医学院学报》.2009,第28卷(第6期),77-78. * |
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Owner name: ANHUI DEEPBLUE MEDICAL TECHNOLOGY CO., LTD. Free format text: FORMER NAME: ANHUI SHENLAN MEDICAL SCIENCE + TECHNOLOGY CO., LTD. |
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Address after: 230022, No. 6, Zhenxing Road, new industrial park, Shushan District, Anhui, Hefei Province three Patentee after: Anhui deep blue medical Polytron Technologies Inc Address before: 230022, 6 floor, Zhenxing Road, Shushan new industrial park, Shushan District, Hefei, Anhui, three Patentee before: Anhui Deepblue Medical Technology Co., Ltd. |
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