CN103536959A - Preparation method of postoperative pharmaceutical adjuvant paste for anorectal diseases - Google Patents
Preparation method of postoperative pharmaceutical adjuvant paste for anorectal diseases Download PDFInfo
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- CN103536959A CN103536959A CN201310489949.8A CN201310489949A CN103536959A CN 103536959 A CN103536959 A CN 103536959A CN 201310489949 A CN201310489949 A CN 201310489949A CN 103536959 A CN103536959 A CN 103536959A
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Abstract
The invention relates to a preparation method of a postoperative pharmaceutical adjuvant paste for anorectal diseases, which can effectively solve the problem of postoperative medication for treating anorectal diseases. According to the technical scheme solving the problem, the adjuvant paste is prepared by adopting the preparation method comprising the following steps: coating medical acrylate mucilage glue on a flexible spunlace non-woven fabric or a ventilating polyurethane film as a paste body; arranging a pure cotton fiber absorption pad core in the middle of the paste body; doping traditional Chinese medicine powder in the pure cotton fiber absorption pad core; and respectively arranging self-adhered adhesive tapes at four corners. The traditional Chinese medicine powder comprises the following raw material medicines by weight: 90-110g of flowers carthami, 140-160g of frankincense, 140-160g of myrrh, 140-160g of red halloysite, 140-160g of gallnut, 140-160g of Bletilla striata, 140-160g of golden cypress and 140-160g of gypsum which are crushed. 10-15g of the traditional Chinese medicine powder is uniformly doped in each 5*8cm<2> pure cotton fiber absorption pad core. The adjuvant paste prepared by using the preparation method provided by the invention satisfies the physiological structure of the buttock of human body in design, not only can prevent wound infection, but also promote wound healing, has good sealing barrier property, moisture permeability and gas permeability, and is innovation of postoperative adjuvants for treating anorectal diseases.
Description
Technical field
The present invention relates to medicine, the manufacture method that particularly the postoperative pharmaceutic adjuvant of a kind of anorectal disease pastes.
Background technology
Anorectal disease is clinical frequently-occurring disease, commonly encountered diseases, most patients need operative treatment, and patient's postoperative wound surface majority is with opening, in addition the factor such as postoperative defecation impact, the problems such as therefore anorectal disease hands postoperative wound surface easily pollutes, wound healing is slow perplex the doctor of anorectal section always, and wound surface and anus secretions is more, ooze out and morely also to patient, bring great trouble, are difficult to nursing, and the particularity at anus position, common adjuvant is difficult to fix, and in active procedure, easily comes off, and is unfavorable for hindering the recovery of face.
Anorectal disease postoperative wound surface mostly is bacterium and has the open wound adopting without sewing up, wound repair is that body is replied the complicated biological process that skin injury shows, mainly comprise the local inflammation stage of reaction, cell proliferation and differentiation and granulation tissue formation stages and tissue reconstruction stage, by vascular endothelial proliferation in wound surface, form gradually newborn blood capillary, with fibroblast, endotheliocyte, the common formation such as new vessels granulation tissue, filling is created chamber or is organized crack, and original blood clot, sloughs etc. can be decomposed by enzyme, leukocytes phagocytic, absorb or discharge from wound.The synthetic precollagen of fibroblast and aminopolysaccharide, in granulation tissue, collagen fiber increase gradually, its hardness and tension force strengthen, granulation tissue changes fibrous tissue grafting between fracture tissue, epithelial hyperplasia combined effect simultaneously makes wound healing, this course of disease is longer, and the postoperative complication such as pain, edge of wound edema, sepage, granulation undergrowth that are prone to.
The reason that wound healing postpones comprises infection, ischemia etc.Postoperative every day fecal pollution wound, wound drainage is not smooth, easily causes secondary infection.The rotten disintegrate of cell during wound infection, some pathogenic bacterium can produce collagenase and destroy collagen, draws together antibacterial and produces toxin and enzyme, solubilising protein and collagen fiber and hinder regeneration.The reason of postoperative open wound surface ischemia has local blood circulation obstacle and local microcirculation disorder, leukocyte is swum out of from blood vessel, in damage zone, engulf in a large number slough, oxygen consumption significantly increases, cause wound blood supply relative deficiency, congested, edema in wound surrounding tissue, vascular compression is another main cause of ischemia.
And Chinese medicine reduces inflammatory stimulus for anorectal disease postoperative wound surface, alleviating pain, promotes to hinder face healing and has unique advantage, and through long-term clinical observation, external application Chinese medicine can effectively reduce the pain of hindering face, prevention infection, and the healing of face is hindered in promotion.
At present for the postoperative Chinese medicine of anorectal disease, be also only confined to postoperative routine and carry out dressing change, and smoked medicine treatment, but postoperatively hinder face medication, mostly be disposable medication, be difficult to play the object continuing medication, curative effect is not good enough, healing postoperative wound surface of anorectal diseases slowly and infection problems letter is to be solved always.Therefore, the improvement of the postoperative adjuvant for the treatment of anorectal disease is the problem of needing at present solution badly.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the present invention's object is just to provide the manufacture method that the postoperative pharmaceutic adjuvant of a kind of anorectal disease pastes, and can effectively solve the postoperative medication problem for the treatment of anorectal disease.
The technical scheme that the present invention solves is, it is with soft spun-laced nonwoven fabric or breathability polyurethane film that this adjuvant pastes, it is fit being coated with medical acrylate viscose glue, there is textile fiber absorbs bedding core fit centre, in textile fiber absorbs bedding core, mix Chinese medicine powder, four jiaos of places respectively have 1 self-adhering type adhesive tape to make, described Chinese medicine powder is the material medicine by following weighing scale: Flos Carthami 90-110g, Olibanum 140-160g, Myrrha 140-160g, Halloysitum Rubrum 140-160g, Galla Chinensis 140-160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 140-160g, Cortex Phellodendri 140-160g and Gypsum Fibrosum 140-160g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 10-15g.
It is 0.5-0.8cm that described adjuvant pastes thickness.
Adjuvant of the present invention is sticked to count and meets human buttock's physiological structure, both can prevent traumatic infection, can promote again to hinder face healing, has good airtight barrier and saturating wet, breathability, is the innovation for the treatment of on the postoperative adjuvant of anorectal disease.
The specific embodiment
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
Described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 90g, Olibanum 140g, Myrrha 140g, Halloysitum Rubrum 140g, Galla Chinensis 140g, Pseudobulbus Bletillae (Rhizoma Bletillae) 140g, Cortex Phellodendri 140g and Gypsum Fibrosum 140g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 10g.
Embodiment 2
Described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 100g, Olibanum 150g, Myrrha 150g, Halloysitum Rubrum 150g, Galla Chinensis 150g, Pseudobulbus Bletillae (Rhizoma Bletillae) 150g, Cortex Phellodendri 150g and Gypsum Fibrosum 150g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 13g.
Embodiment 3
Described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 110g, Olibanum 160g, Myrrha 160g, Halloysitum Rubrum 160g, Galla Chinensis 160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 160g, Cortex Phellodendri 160g and Gypsum Fibrosum 160g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 15g.
In said components, wherein:
Flos Carthami: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.For dysmenorrhea, amenorrhea, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke.
Olibanum: nature and flavor: arduous, temperature.Enter the heart, liver, spleen channel.Regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha: nature and flavor: hardship, pungent, flat.Hair growing, the speckle dispelling trace that disappears, softening the hard mass is except tumor, and except tinea more wound, teeth consolidating be good for gum, detoxifies etc.Control alopecia capillary, black speck scar, verruca plana, various eczema, gingiva is rotten to the corn, and poisonous insect stings wound etc.
Halloysitum Rubrum: nature and flavor: sweet; Puckery; Acid; Temperature; Nontoxic.Effect: astringing intestine to stop diarrhea; Astringing to arrest bleeding; Removing dampness sore; Granulation promoting.Cure mainly: chronic diarrhea; Chronic dysentery; Have blood in stool; Proctoptosis; Seminal emission; Metrorrhagia; Leukorrhagia; Ulcer being unable to heal; Eczema; Traumatic hemorrhage.
Galla Chinensis: meridian distribution of property and flavor: sour in the mouth is puckery, cold in nature.Return lung, large intestine, kidney channel.Effect: astringe the lung; Hidroschesis; Astringing intestine to stop diarrhea; Controlling nocturnal emission with astringent drugs; Hemostasis; Removing toxic substances.Cure mainly: chronic cough of deficiency lung; Spontaneous sweating; Chronic dysentery chronic diarrhea; Proctoptosis; Seminal emission; Nebulousurine; Various hemorrhage; Carbuncle furuncle.
The Pseudobulbus Bletillae (Rhizoma Bletillae): nature and flavor: bitter, sweet, puckery, be slightly cold.Gui Jing: return lung, liver, stomach warp.Effect: astringing to arrest bleeding, detumescence and promoting granulation.Cure mainly: for hemoptysis, spit blood, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Cortex Phellodendri: meridian distribution of property and flavor: hardship, cold.Return kidney, bladder, large intestine channel.Function with cure mainly: heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Gypsum Fibrosum: Gypsum Fibrosum is cool in nature, has the effect of heat-clearing and toxic substances removing.
Dressing paste of the present invention combines Chinese Herbs and the effect of applying ointment or plaster cleverly, both can prevent traumatic infection, can promote again to hinder face healing, Chinese medicinal components science, reasonable compatibility, support mutually, the effect with astringing to arrest bleeding, heat-clearing and toxic substances removing, regulating qi and activating blood, has good curative effect in clinical use.Correlation test data is as follows:
(1), inclusion criteria:
Choose at random 100 routine mixed hemorrhoid postoperative patients, male 55 examples wherein, female's 45 examples, the age is (30.6 ± 11.3) year.
(2), therapeutic scheme
After changing dressings after 50 routine operation in patients, use medical dressing to paste, after 50 routine changing dressing for patients, use common adjuvant, according to wound healing time, pain incidence rate and wound infection statistics curative effect.
(3), statistical procedures:
by choosing at random 100 routine mixed hemorrhoid postoperative patient paired observations, study, after changing dressings after 50 routine operation in patients, use medical dressing to paste, after 50 routine changing dressing for patients, use common adjuvant, by clinical observation, study, result is used pharmaceutic adjuvant subsides to organize average wound healing time 15.4 days; Pain incidence rate (marking over 6 minutes with Vas) 13.1%; Without infected patient.Use common adjuvant group, average wound healing time 20.7 days; Pain incidence rate (marking over 6 minutes with Vas) 34.6%; Wound infection 3%.Result pharmaceutic adjuvant subsides group curative effect is obviously due to common adjuvant matched group, and effect is remarkable.
(4), conclusion
By Long-term Clinical Observation, this adjuvant pastes the healing that can obviously promote wound surface, alleviates postoperative pain, and infection rate.The postoperative pharmaceutic adjuvant of anorectal disease of the present invention pastes has good airtight barrier and saturating wet, breathability, the features such as imbibition is effective, this dressing paste is with its distinctive " Webweb " structure, by " three isolation " and " respiratory metabolism " function to wound surface, realized maintenance wound surface physiology moist environment, slough is got rid of in liquefaction, bring into play the advantage that Chinese medicine promotes that anorectal disease postoperative wound surface recovers simultaneously, make the curative effect of Chinese medicine act on all the time wound surface, activate wound surface epidermal stem cells, promote tissue repair cell regeneration, arrive the quick physiological healing of wound surface.Therefore the postoperative pharmaceutic adjuvant of anorectal disease pastes the effect with good pain relieving, infection, wound healing.
Compared with prior art, the present invention has the following advantages:
1, this dressing paste combines Chinese Herbs and the effect of applying ointment or plaster cleverly, both can prevent traumatic infection, can promote again to hinder face healing, has good curative effect in clinical use.
2, this dressing paste can effectively absorb crissum secretions, keeps the drying property of wound surface, breathability, the anal skin irritation of having avoided wound surface to ooze out too much causing.
3, by the persistence effect of medicine, the advantage of performance Chinese medicine in treatment, the healing of face is hindered in promotion.
4, the skin edge hypertrophy causing due to inflammatory stimulus in wound surface recovery process, edema wound have been reduced.
5, easy to use, effect is remarkable.
Claims (4)
1. the manufacture method that the postoperative pharmaceutic adjuvant of an anorectal disease pastes, it is characterized in that, it is with soft spun-laced nonwoven fabric or breathability polyurethane film that this adjuvant pastes, it is fit being coated with medical acrylate viscose glue, there is textile fiber absorbs bedding core fit centre, in textile fiber absorbs bedding core, mix Chinese medicine powder, four jiaos of places respectively have 1 self-adhering type adhesive tape to make, described Chinese medicine powder is the material medicine by following weighing scale: Flos Carthami 90-110g, Olibanum 140-160g, Myrrha 140-160g, Halloysitum Rubrum 140-160g, Galla Chinensis 140-160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 140-160g, Cortex Phellodendri 140-160g and Gypsum Fibrosum 140-160g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 10-15g.
2. the manufacture method that the postoperative pharmaceutic adjuvant of anorectal disease according to claim 1 pastes, it is characterized in that, described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 90g, Olibanum 140g, Myrrha 140g, Halloysitum Rubrum 140g, Galla Chinensis 140g, Pseudobulbus Bletillae (Rhizoma Bletillae) 140g, Cortex Phellodendri 140g and Gypsum Fibrosum 140g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 10g.
3. the manufacture method that the postoperative pharmaceutic adjuvant of anorectal disease according to claim 1 pastes, it is characterized in that, described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 100g, Olibanum 150g, Myrrha 150g, Halloysitum Rubrum 150g, Galla Chinensis 150g, Pseudobulbus Bletillae (Rhizoma Bletillae) 150g, Cortex Phellodendri 150g and Gypsum Fibrosum 150g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 13g.
4. the manufacture method that the postoperative pharmaceutic adjuvant of anorectal disease according to claim 1 pastes, it is characterized in that, described Chinese medicine powder is by the material medicine of following weighing scale: Flos Carthami 110g, Olibanum 160g, Myrrha 160g, Halloysitum Rubrum 160g, Galla Chinensis 160g, Pseudobulbus Bletillae (Rhizoma Bletillae) 160g, Cortex Phellodendri 160g and Gypsum Fibrosum 160g pulverize and form, every 5 * 8cm
2textile fiber absorbs bedding core in evenly mix Chinese medicine powder 15g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310489949.8A CN103536959B (en) | 2013-10-18 | 2013-10-18 | Preparation method of postoperative pharmaceutical adjuvant paste for anorectal diseases |
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| CN201310489949.8A CN103536959B (en) | 2013-10-18 | 2013-10-18 | Preparation method of postoperative pharmaceutical adjuvant paste for anorectal diseases |
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| CN103536959A true CN103536959A (en) | 2014-01-29 |
| CN103536959B CN103536959B (en) | 2015-04-22 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103768448A (en) * | 2014-02-18 | 2014-05-07 | 王立凤 | Traditional Chinese medicinal granules for fumigation hip bath for relieving swelling and pain after anorectal surgery |
| CN103920010A (en) * | 2014-05-05 | 2014-07-16 | 福建中合医药有限责任公司 | Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2671571Y (en) * | 2003-08-28 | 2005-01-19 | 济南弘康医疗保健科技开发有限公司 | Medicinal plaster for anus |
| CN101524304A (en) * | 2009-03-16 | 2009-09-09 | 凌峰 | Disposable anorectal wound nursing article |
| CN101584877A (en) * | 2009-06-15 | 2009-11-25 | 于向英 | Packed medicament plaster for laparoscopic surgery |
-
2013
- 2013-10-18 CN CN201310489949.8A patent/CN103536959B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2671571Y (en) * | 2003-08-28 | 2005-01-19 | 济南弘康医疗保健科技开发有限公司 | Medicinal plaster for anus |
| CN101524304A (en) * | 2009-03-16 | 2009-09-09 | 凌峰 | Disposable anorectal wound nursing article |
| CN101584877A (en) * | 2009-06-15 | 2009-11-25 | 于向英 | Packed medicament plaster for laparoscopic surgery |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103768448A (en) * | 2014-02-18 | 2014-05-07 | 王立凤 | Traditional Chinese medicinal granules for fumigation hip bath for relieving swelling and pain after anorectal surgery |
| CN103920010A (en) * | 2014-05-05 | 2014-07-16 | 福建中合医药有限责任公司 | Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof |
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| CN103536959B (en) | 2015-04-22 |
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Granted publication date: 20150422 Termination date: 20161018 |