CN102861151B - Traditional Chinese medicine compound for treating bedsores - Google Patents
Traditional Chinese medicine compound for treating bedsores Download PDFInfo
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- CN102861151B CN102861151B CN201210408001.0A CN201210408001A CN102861151B CN 102861151 B CN102861151 B CN 102861151B CN 201210408001 A CN201210408001 A CN 201210408001A CN 102861151 B CN102861151 B CN 102861151B
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Abstract
The invention discloses a traditional Chinese medicine compound for treating bedsores and belongs to traditional Chinese medicine compounds. The traditional Chinese medicine compound for treating the bedsores is composed of garden burnet, pseudo-ginseng, cuttlebones, rheum officinale, arnebia roots, angelica dahurica, white alums and Chinese galls based on a certain weight ratio. The traditional Chinese medicine compound for treating the bedsores has the efficacy of astringing exudation, regenerating new tissue, relieving swelling and pain, antibiosis, healing sores, stopping bleeding and removing stasis, and the bedsores can be effectively treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of decubital ulcer.
Background technology
Decubital ulcer, is called again " pressure ulcer ", is with skin injury, and the open sore part is prolonged is not more feature, and how because of prolonged illness bed, QI-blood circulation is lost smooth, and failure of skin and muscle to be nourished is every because friction skin is broken, contamination forms.Clinical syndrome differentiation is divided into qi depression to blood stasis, accumulates excess syndrome and the deficiency of both QI and blood of malicious decomposed.Clinically, be divided into decubital ulcer I degree (erythema phase), decubital ulcer II degree (vesicle phase) and three phases of decubital ulcer III degree (ulcerative stage) according to the forming process of decubital ulcer and the order of severity.Show as in the erythema phase: the compression zone position of whole body shows as local stasis of blood, and skin presents erythema; The vesicle phase shows as: the blister differing in size appears in pressurized position, and skin rubefaction hyperemia is not disappeared while pressure with finger; Ulcerative stage shows as: ulcer is no more than skin holostrome, because ulcer basilar part lacks blood supply, is pale asphyxia, granulation edema, and flowing water is more than, and severe patient involves fascia and muscle, and traumatic infection is serious.Once decubital ulcer occurs, and cures more difficultly, if secondary infection can aggravate disease, severe patient even can cause osteomyelitis, septicemia and hypoproteinemia threat to life.Approximately there are every year 60000 people to die from decubital ulcer complication according to related documents report, now become typical bed patient's No.1 " killer ".Decubital ulcer has not only been brought misery to patient, even directly threatens patient's life, for prolonged illness sickbed patients, has more increased their spirit and living burden.At present treat clinically decubital ulcer and also there is no ideal medicine.Doctor trained in Western medicine surgical operation therapy is only for the patient who is in a bad way, but has risk and opening is large, and patient suffering is large, expense is high, healing is slow.It is only effective to traumatic infection using antibiotic therapy decubital ulcer, but affects wound healing time.The medicine of existing treatment decubital ulcer among the people is mostly made by oneself personal, and individualized treatment situation is serious, there is no unified treatment by Chinese herbs.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, it is fast that this Chinese medicine composition has wound healing for treatment decubital ulcer, and pain relieving is fast, and infection is strong, and preparation is simple, feature easy to use.
The present invention selects Radix Sanguisorbae, Radix Notoginseng, Endoconcha Sepiae, Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, Alumen and Galla Chinensis to combine, make each efficacy of drugs produce synergism these drug regimens, make it to have effect of convergence granulation promoting, reducing swelling and alleviating pain, antibacterial sore, hemostasia and dissipation blood stasis, thereby can effectively treat decubital ulcer.
The effect of Chinese medicine of the present invention:
Wherein: Radix Sanguisorbae: the dry root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.Cold in nature, bitter in the mouth, acid, puckery, nontoxic.Return liver, lung, kidney, large intestine channel.Effect: cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.There is the effect of convergence, antibacterial, antiinflammatory and hemostasis.
Radix Notoginseng: the dry root of panax araliaceae plant.Warm in nature, sweet in the mouth, micro-hardship, nontoxic.Return liver, stomach warp.Effect: dissipating blood stasis hemostasis; Subduing swelling and relieving pain.There is the effect of hemostasis, blood circulation promoting and blood stasis dispelling.
Endoconcha Sepiae: be the dry inner shell of Sepiidae animal sepiella maindroni de Rochebrune or golden cuttlefish.Warm in nature, salty in the mouth, puckery.Return spleen, kidney channel.Effect: astringing to arrest bleeding, pain relieving, removing dampness sore.The shallow degree of the Endoconcha Sepiae treated powder phase decubital ulcer of festering is effective, has good friction and adsorption, not only can destroy the conjunctival epithelium tissue of pathological changes, again the adsorbable blood that has toxin and an antibacterial with ooze out mucus, receive the rotten pus of the open sore part.
Radix Et Rhizoma Rhei: be the dry root and rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Cold in nature, bitter in the mouth.Return large intestine, liver, spleen channel.Effect: heat clearing and blood cooling, blood stasis dispelling removing toxic substances.Anastalsis is definite, instant effect, and responsive antibacterial is had to anti-infectious function as staphylococcus, Hemolytic streptococcus, micrococcus gonococcus, diphtheria corynebacterium, Bacillus typhi, dysentery bacterium etc.
Radix Arnebiae (Radix Lithospermi): be the root of comfrey Radix Arnebiae (Radix Lithospermi), the false Radix Arnebiae (Radix Lithospermi) in Xinjiang-Tibet or Yunnan Radix Arnebiae (Radix Lithospermi).Cold in nature, sweet in the mouth, salty.GUIXIN, Liver Channel.Effect: removing heat from blood, invigorate blood circulation, removing toxic substances rash.Shikonin all has obvious bacteriostasis to escherichia coli, Bacillus typhi, dysentery bacterium, bacillus pyocyaneus and staphylococcus aureus, and can increase granulation growth, promotes wound healing.
The Radix Angelicae Dahuricae: be the dry root of the samphire Radix Angelicae Dahuricae or Radix angelicae dahuricae.Warm in nature, acrid in the mouth.Attach to the lung and stomach meridians.Effect: the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, expelling wind and cold, detumescence dampness.Have antibacterial action, the Radix Angelicae Dahuricae has inhibitory action in various degree to escherichia coli, Song Shi and bacterium flexneri, Bacillus proteus, Typhoid and paratyphoid bacillus, bacillus pyocyaneus, vibrio cholera, some gram-positive bacteria and Bacillus tuberculosis etc. in vitro.
Alumen: be the potassium sulfate that contains water of crystallization and the double salt of aluminum sulfate.Cold in nature, sour in the mouth, puckery is poisonous.Effect: hemostasis convergence, antipyretic and itching-stopping.Alumen has inhibitory action to multiple Grain-negative, positive coccus and bacillus; Common suppuration bacterium is had to stronger bacteriostasis.
Galla Chinensis: be the insect gall forming after the upper parasitic times Aphidiadae insecticide Chinese Nut-gall aphid of the trees such as Anacardiaceae plant Fructus rhois chinensis, blue or green bran poplar and Radix Rhois Sinicae or melaphis peitan Tsai et Tang.Cold in nature, sour in the mouth, puckery.Return lung, large intestine, kidney channel.Effect: hemostasis, removing toxic substances.Galla Chinensis contains tannic acid, has the effect of precipitating proteins, and after skin ulcer face, mucosa are in contact with it, tissue protein is solidified, and forms layer protecting film, has astriction, simultaneously also oppressed contraction of little blood vessel, blood clotting and be anastalsis.Galla Chinensis all has significantly antibacterial or bactericidal action to staphylococcus aureus, streptococcus, streptococcus pneumoniae and typhoid fever, paratyphoid fever, dysentery, anthrax, diphtheria, bacillus pyocyaneus etc. in vitro.
Medicine material consumption of the present invention is groped in a large number to sum up through inventor and is drawn, each raw material consumption is for all to have good curative effect in following weight parts scope: Radix Sanguisorbae 25-35 part, Radix Notoginseng 25-35 part, Endoconcha Sepiae 25-35 part, Radix Et Rhizoma Rhei 25-35 part, Radix Arnebiae (Radix Lithospermi) 25-35 part, Radix Angelicae Dahuricae 25-35 part, Alumen 45-55 part, Galla Chinensis 45-55 part.
Wherein be preferably: 30 parts of Radix Sanguisorbaes, 30 parts of Radix Notoginseng, 30 parts of Endoconcha Sepiaes, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of the Radixs Angelicae Dahuricae, 50 parts, Alumen, 50 parts of Galla Chinensiss.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into powder or unguentum.These crude drug pulverization mix homogeneously are made to powder external application or medicated powder furnishing paste is smeared with Oleum Sesami or Oleum Verniciae fordii.
Medicine of the present invention has the effects such as convergence granulation promoting, reducing swelling and alleviating pain, antibacterial sore, hemostasia and dissipation blood stasis, wound healing is fast, pain relieving is fast, infection is strong, preparation is simple, easy to use, according to clinical 200 routine patients are observed to statistics, use 85%, two of one of the medicine of the present invention total effective rate course for the treatment of total effective rate course for the treatment of 93%.
The specific embodiment
Embodiment mono-, 25 parts of Radix Sanguisorbaes, 25 parts of Radix Notoginseng, 25 parts of Endoconcha Sepiaes, 25 parts of Radix Et Rhizoma Rhei, 25 parts of Radix Arnebiae (Radix Lithospermi)s, 25 parts of the Radixs Angelicae Dahuricae, 45 parts, Alumen, 45 parts of Galla Chinensiss.
Embodiment bis-, 30 parts of Radix Sanguisorbaes, 30 parts of Radix Notoginseng, 30 parts of Endoconcha Sepiaes, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of the Radixs Angelicae Dahuricae, 50 parts, Alumen, 50 parts of Galla Chinensiss.
Embodiment tri-, 35 parts of Radix Sanguisorbaes, 35 parts of Radix Notoginseng, 35 parts of Endoconcha Sepiaes, 35 parts of Radix Et Rhizoma Rhei, 35 parts of Radix Arnebiae (Radix Lithospermi)s, 35 parts of the Radixs Angelicae Dahuricae, 55 parts, Alumen, 55 parts of Galla Chinensiss.
The clinical statistics data that patient uses medicine of the present invention below:
One, physical data
Accept out-patient's totally 200 examples for medical treatment, wherein male's 104 examples, women's 96 examples, M-F 1.1:1,58 years old mean age.
Two, tcm diagnosis standard
Diagnostic criteria with reference to decubital ulcer in People's Republic of China's Chinese medicine industry standard " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
1, being apt to occur in the apophysis such as tail sacrum, ridge, elbow ankle easily suffers oppression and rubs position.
2, from the beginning of occurring brown erythema on skin, micro-swollen, purple dark edema then, necrosis is festered.
3, when secondary is contaminated, tissue necrosis is rapid, and pus is dripping, corresponding site Bing Fa Xing core pain.
4, be more common in the patient of the prolonged illness beds such as stupor, paralysis, fracture, large-area burns.
Three, Therapeutic Method
First clean wound surface, then spreading medicated powder with normal saline or 3% hydrogen peroxide.Answer under aseptic condition and puncture if any blister, push epidermis aside, powder again spreads pesticides after emptying bubble liquid; As rarely seen local red and swollen, medicated powder furnishing paste is coated with affected part by available Oleum Sesami or Oleum Verniciae fordii.While changing dressings, as found, injury festers, and should wipe the powder that spreads pesticides again after pus away.Changing dressings every day 1 time, 15th is a course for the treatment of.
Four, efficacy assessment standard
Efficacy assessment standard with reference to decubital ulcer in People's Republic of China's Chinese medicine industry standard " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
Cure: brown erythema disappears, or the wound healing that festers.
Take a turn for the better: erythema does not disappear entirely, or the skin ulcer face slough that festers comes off, granulation, skin ulcer face dwindles gradually.
Do not heal: the open sore part increases, fester more than.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, Zhang, man, 65 years old, decubital ulcer position sacrococcygeal region,, there is blood stasis in area 2cm × 3cm, skin presents erythema, numbness, subcutaneous tissue keeps normal elasticity, and integrity does not destroy.Use medicated powder of the present invention to be modulated into cream drug and smear, medication, after ten days, is examined inspection and is had no blood stasis and erythema.
Case two, close certain, female, 74 years old, decubital ulcer position sacrococcygeal region, area 3cm × 3cm, infects in shallow layer tissue, has yellow water sample exudate, has formed ulcer.Wound surface, with after normal saline flushing, is used to the even spreading wound surface of medicated powder of the present invention, then wrap up with sterile gauze.After the course for the treatment of of continuous use, when further consultation, ooze out without secretions, the fresh granulation tissue growth of part, wound surface dwindles, and continues after the course for the treatment of of medication, and wound surface has been formed a scab dry and comfortable.
Case three, Wang, female, 76 years old, hemiparalysis after apoplexy, decubital ulcer area 6cm × 7cm, wound tissue necrosis, has a large amount of purulent secretions and with stench taste, infects tissue and deep diffusion towards periphery.Adopt 3% hydrogen peroxide to rinse wound surface, and wipe out slough, then use normal saline flushing wound surface 2 times, medicated powder of the present invention is evenly sprinkling upon on wound surface, and then, with sterile gauze wrapping, pressurized should be avoided in wrapping position, after two courses for the treatment of of continuous use, the wound surface open sore part is healing completely.
Claims (2)
1. treat the Chinese medicine composition of decubital ulcer for one kind, it is characterized in that, this Chinese medicine composition is the ingredients by following weight portion: Radix Sanguisorbae 25-35 part, Radix Notoginseng 25-35 part, Endoconcha Sepiae 25-35 part, Radix Et Rhizoma Rhei 25-35 part, Radix Arnebiae (Radix Lithospermi) 25-35 part, Radix Angelicae Dahuricae 25-35 part, Alumen 45-55 part, Galla Chinensis 45-55 part, above-mentioned raw materials medicine pulverization mix homogeneously is made to powder.
2. the Chinese medicine composition for the treatment of decubital ulcer according to claim 1, it is characterized in that, ingredients by following weight portion: 30 parts of Radix Sanguisorbaes, 30 parts of Radix Notoginseng, 30 parts of Endoconcha Sepiaes, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of the Radixs Angelicae Dahuricae, 50 parts, Alumen, 50 parts of Galla Chinensiss, above-mentioned raw materials medicine pulverization mix homogeneously is made to powder.
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CN104547644A (en) * | 2015-01-09 | 2015-04-29 | 王乃伟 | Bedsore paste |
CN105727194A (en) * | 2016-03-16 | 2016-07-06 | 烟台市蓝洋之草医药生物科技有限公司 | Application of traditional Chinese medicine composition to preparation of medicines for treating bedsore |
CN105561216A (en) * | 2016-03-16 | 2016-05-11 | 烟台市蓝洋之草医药生物科技有限公司 | Traditional Chinese medicine composition for treating bedsore and preparation method of traditional Chinese medicine composition |
CN108186840A (en) * | 2018-03-22 | 2018-06-22 | 邓丽丽 | A kind of wound for the treatment of accumulates Chinese medicine ointment of malicious rotten routed pain and preparation method thereof |
CN109453228A (en) * | 2019-01-07 | 2019-03-12 | 刘春生 | A kind of Chinese medicine composition for treating bedsore and diabetic complication |
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