CN105169317A - Preparation method of scar-removing ointment - Google Patents

Abstract

The invention relates to a preparation method of a scar-removing ointment and belongs to the field of traditional Chinese medicines. The method comprises the following steps: firstly, juicing fresh ginger and aloe, collecting juice, sterilizing the juice at high temperature, performing standing, cooling and centrifugal separation, and extracting a supernatant for later use; secondly, mixing the supernatant and deionized water in parts by weight in a beaker, and performing heating, purifying and vacuum flashing to obtain an aloe-ginger mixed water solution; thirdly, mixing chitosan powder, an acetic acid solution, liquid paraffin and sorbitan fatty acid ester to form an emulsifier, performing stirring to obtain a chitosan emulsion water solution, and mixing the chitosan emulsion water solution and the aloe-ginger mixed water solution to prepare a natural scar-removing dressing water solution; finally, sealing, stirring and mixing polyvinyl alcohol, polyvinylpyrrolidone, the natural scar-removing dressing water solution, methyl salicylate and the deionized water, and performing standing and defoaming to obtain the scar-removing ointment. The preparation method of the scar-removing ointment has the beneficial effects of short repair time, good repair effect, low cost and no side effects.

Description

A kind of preparation method of scar ointment of dispelling

Technical field

The present invention relates to a kind of preparation method of scar ointment of dispelling, belong to the field of Chinese medicines.

Background technology

Cicatrix refers to the mode of appearance of normal skin tissue caused after various wound and the general designation of histopathologic change.It is after human body wound, and a kind of normal, the inevitable physiological reaction in wound or wound surface normal healing process is also the inevitable outcome of wound healing process.The essence of cicatrix does not a kind ofly possess normal skin tissue's structure and physiological function, loses normal structure vigor, abnormal, unsound tissue.Cicatrix not only destroys surface, also can hinder the physiological function of linked groups or organ, even cause deformity.

Several treating acne methods conventional at present: as excision cicatrix noinvasive is sewed up, repair cicatrix, drug injection in cicatrix after soft tissue expander's expansion normal skin, cicatrix attritions etc., can improve outward appearance, alleviate scar hyperplasia, but cicatrix can not be repaired completely, and residual sequela, there is side effect.

Summary of the invention

The technical problem that the present invention mainly solves: cicatrix can not be repaired completely for repairing cicatrix at present, bring side effect, provide a kind of preparation method of scar ointment of dispelling, the method by chitosan aqueous emulsion with mix Aloe Rhizoma Zingiberis Recens aqueous solution, obtain scar ointment of dispelling, this scar of dispelling is effective, shortens healing time, and healing wound surface is smooth without cicatrix, has no side effect.

In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is,

(1) 1:1 counts in mass ratio, choose fresh ginger and fresh aloe, squeezed the juice and extruded with gauze, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 90 ~ 100 DEG C of high temperature sterilization 3 ~ 5min are heated to it, left standstill after being cooled to 20 ~ 25 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant;

(2) count by weight, the deionized water mixing choosing the supernatant of 20 ~ 30 parts and 70 ~ 80 parts is placed in beaker, be heated to 80 DEG C ~ 140 DEG C, carry out heating to it to purify, to its vacuum flashing after 30 ~ 40min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 38% ~ 42%, for subsequent use;

(3) count by weight, choose 5 ~ 35 parts of Chitosan powder, 20 ~ 40 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 30 ~ 40 parts and 15 ~ 25 parts forms emulsifying agent, mix and blend 30min at 20 ~ 30 DEG C, mix and blend speed is 1000 ~ 1200r/min, obtains chitosan aqueous emulsion for subsequent use;

(4) the mixing Aloe gingerade solution prepared by the chitosan aqueous emulsion of above-mentioned preparation and step (2), 1:1 carries out being uniformly mixed 20 ~ 30min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use;

(5) more by mass percentage, choose the polyvinyl alcohol of 20 ~ 25%, 1 ~ 3% polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 6 ~ 20%, the methyl salicylate of 1.95mol/L of 8 ~ 12% and the deionized water of 40 ~ 65% to carry out sealing and be uniformly mixed, mixing temperature is 15 ~ 20 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one and to dispel scar ointment.

Application of the present invention: by obtained scar ointment uniform application of dispelling in cicatrix, every day sooner or later once, finds that cicatrix reparation shifts to an earlier date 7 ~ 8 days than original repair time.

The invention has the beneficial effects as follows:

(1) shorten repair time, repairing effect is good;

(2) cost is little, has no side effect.

Detailed description of the invention

First 1:1 meter in mass ratio, choose fresh ginger and fresh aloe, squeezed the juice and extruded with gauze, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 90 ~ 100 DEG C of high temperature sterilization 3 ~ 5min are heated to it, left standstill after being cooled to 20 ~ 25 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant; Count by weight, the deionized water mixing choosing the supernatant of 20 ~ 30 parts and 70 ~ 80 parts is placed in beaker, be heated to 80 DEG C ~ 140 DEG C, carry out heating to it to purify, to its vacuum flashing after 30 ~ 40min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 38% ~ 42%, for subsequent use; Count by weight, choose 5 ~ 35 parts of Chitosan powder, 20 ~ 40 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 30 ~ 40 parts and 15 ~ 25 parts forms emulsifying agent, mix and blend 30min at 20 ~ 30 DEG C, mix and blend speed is 1000 ~ 1200r/min, obtains chitosan aqueous emulsion for subsequent use; Again by the chitosan aqueous emulsion of above-mentioned preparation and mixing Aloe gingerade solution, 1:1 carries out being uniformly mixed 20 ~ 30min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use; Again by mass percentage, choose the polyvinyl alcohol of 20 ~ 25%, 1 ~ 3% polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 6 ~ 20%, the methyl salicylate of 1.95mol/L of 8 ~ 12% and the deionized water of 40 ~ 65% to carry out sealing and be uniformly mixed, mixing temperature is 15 ~ 20 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one and to dispel scar ointment.

Example 1

First choose 100g fresh ginger and 100g fresh aloe, squeezed the juice and with gauze extruding, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 100 DEG C of high temperature sterilization 5min are heated to it, left standstill after being cooled to 25 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant; Count by weight, the deionized water mixing choosing the supernatant of 30 parts and 70 parts is placed in beaker, is heated to 140 DEG C, carries out heating purification, to its vacuum flashing after 40min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 42% to it, for subsequent use; Count by weight, choose 35 parts of Chitosan powder, 20 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 30 parts and 15 parts forms emulsifying agent, mix and blend 30min at 30 DEG C, mix and blend speed is 1200r/min, obtains chitosan aqueous emulsion for subsequent use; Again by the chitosan aqueous emulsion of above-mentioned preparation and mixing Aloe gingerade solution, 1:1 carries out being uniformly mixed 30min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use; Again by gross mass 100g, choose the polyvinyl alcohol of 20g, 1g polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 6g, the methyl salicylate of 1.95mol/L of 8g and the deionized water of 65g to carry out sealing and be uniformly mixed, mixing temperature is 15 ~ 20 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one to dispel scar ointment, by obtained scar ointment uniform application of dispelling in cicatrix, every day sooner or later once, find that cicatrix reparation only needs 10 days, repairing effect is good.

Example 2

First choose 200g fresh ginger and 200g fresh aloe, squeezed the juice and with gauze extruding, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 90 DEG C of high temperature sterilization 3min are heated to it, left standstill after being cooled to 20 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant; Count by weight, the deionized water mixing choosing the supernatant of 20 parts and 80 parts is placed in beaker, is heated to 80 DEG C, carries out heating purification, to its vacuum flashing after 30min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 38% to it, for subsequent use; Count by weight, choose 5 parts of Chitosan powder, 40 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 40 parts and 15 parts forms emulsifying agent, mix and blend 30min at 20 DEG C, mix and blend speed is 1000r/min, obtains chitosan aqueous emulsion for subsequent use; Again by the chitosan aqueous emulsion of above-mentioned preparation and mixing Aloe gingerade solution, 1:1 carries out being uniformly mixed 20min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use; Again by gross mass 200g, choose the polyvinyl alcohol of 50g, 6g polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 12g, the methyl salicylate of 1.95mol/L of 16 and the deionized water of 116g to carry out sealing and be uniformly mixed, mixing temperature is 15 ~ 20 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one to dispel scar ointment, by obtained scar ointment uniform application of dispelling in cicatrix, every day sooner or later once, find that cicatrix reparation only needs 11 days, repairing effect is good.

Example 3

First choose 150g fresh ginger and 150g fresh aloe, squeezed the juice and with gauze extruding, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 95 DEG C of high temperature sterilization 4min are heated to it, left standstill after being cooled to 22 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant; Count by weight, the deionized water mixing choosing the supernatant of 25 parts and 75 parts is placed in beaker, is heated to 100 DEG C, carries out heating purification, to its vacuum flashing after 35min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 40% to it, for subsequent use; Count by weight, choose 30 parts of Chitosan powder, 20 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 30 parts and 20 parts forms emulsifying agent, mix and blend 30min at 25 DEG C, mix and blend speed is 1000r/min, obtains chitosan aqueous emulsion for subsequent use; Again by the chitosan aqueous emulsion of above-mentioned preparation and mixing Aloe gingerade solution, 1:1 carries out being uniformly mixed 25min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use; Again by gross mass 300g, choose the polyvinyl alcohol of 66g, 6g polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 45g, the methyl salicylate of 1.95mol/L of 30g and the deionized water of 153g to carry out sealing and be uniformly mixed, mixing temperature is 17 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one to dispel scar ointment, by obtained scar ointment uniform application of dispelling in cicatrix, every day sooner or later once, find that cicatrix reparation only needs 9 days, repairing effect is good.

Claims (1)

1. a preparation method for scar of dispelling ointment, is characterized in that concrete preparation process is:

(1) 1:1 counts in mass ratio, choose fresh ginger and fresh aloe, squeezed the juice and extruded with gauze, collect the mixing juice without Rhizoma Zingiberis Recens and Aloe slag, 90 ~ 100 DEG C of high temperature sterilization 3 ~ 5min are heated to it, left standstill after being cooled to 20 ~ 25 DEG C subsequently, centrifugalize, for subsequent use after getting its supernatant;

(2) count by weight, the deionized water mixing choosing the supernatant of 20 ~ 30 parts and 70 ~ 80 parts is placed in beaker, be heated to 80 DEG C ~ 140 DEG C, carry out heating to it to purify, to its vacuum flashing after 30 ~ 40min to be purified, obtain the mixing Aloe gingerade solution that mass fraction is 38% ~ 42%, for subsequent use;

(3) count by weight, choose 5 ~ 35 parts of Chitosan powder, 20 ~ 40 parts of mass fractions are the acetic acid solution of 36%, the sorbitan fatty ester mixed preparing of the liquid paraffin of 30 ~ 40 parts and 15 ~ 25 parts forms emulsifying agent, mix and blend 30min at 20 ~ 30 DEG C, mix and blend speed is 1000 ~ 1200r/min, obtains chitosan aqueous emulsion for subsequent use;

(4) the mixing Aloe gingerade solution prepared by the chitosan aqueous emulsion of above-mentioned preparation and step (2), 1:1 carries out being uniformly mixed 20 ~ 30min in mass ratio, after it has stirred, is prepared into the natural dressing aqueous solution of scar of dispelling, for subsequent use;

(5) more by mass percentage, choose the polyvinyl alcohol of 20 ~ 25%, 1 ~ 3% polyvinylpyrrolidone, the natural dressing aqueous solution of scar of dispelling of 6 ~ 20%, the methyl salicylate of 1.95mol/L of 8 ~ 12% and the deionized water of 40 ~ 65% to carry out sealing and be uniformly mixed, mixing temperature is 15 ~ 20 DEG C, standing and defoaming after being cooled to 20 DEG C after having mixed, can obtain one and to dispel scar ointment.