CN105816377A - Wrinkle-free repair cream and preparation method thereof - Google Patents

Wrinkle-free repair cream and preparation method thereof Download PDF

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CN105816377A
CN105816377A CN201610237067.6A CN201610237067A CN105816377A CN 105816377 A CN105816377 A CN 105816377A CN 201610237067 A CN201610237067 A CN 201610237067A CN 105816377 A CN105816377 A CN 105816377A
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emulsifying pot
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冯昱钦
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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Abstract

The invention relates to wrinkle-free repair cream. The wrinkle-free repair cream is prepared from the following raw materials in parts by weight: 40 to 80 parts of water, 2.5 to 4 parts of glycerol, 4 to 7 parts of butanediol, 0.8 to 1.2 parts of hydrolyzed collagen, 0.1 to 0.5 part of hyaluronic acid, 0.5 to 1 part of panthenol, 0.8 to 1.2 parts of evening primrose seed extracts, 0.8 to 1.2 parts of oligopeptide-1, 0.8 to 1.2 parts of oligopeptide-2, 1.6 to 2.4 parts of mycose, 4 to 6 parts of horse fat, 0.7 to 1.3 parts of centella asiatica root extracts, 1.3 to 1.8 parts of syringa vulgaris extracts, 1.7 to 2.3 parts of ceteareth-10, 1.3 to 1.8 parts of cetearyl alcohol, 1.7 to 2.3 parts of Shea butter oil and the like. According to the wrinkle-free repair cream and a preparation method of the wrinkle-free repair cream disclosed by the invention, the wrinkle-free repair cream is convenient to use, good in permeability, mild in skin and free of stimulation and harms to skin, and capable of stimulating growth factors to play a role based on the activity of resina draconis.

Description

A kind of without stricture of vagina repair cream and preparation method thereof
Technical field:
The present invention relates to a kind of without stricture of vagina repair cream and preparation method thereof.
Background technology:
Along with the raising day by day of living standard, beautiful idea is increasingly valued by people, striae gravidarum, eyeprint, Cicatrix, pox print etc. are all the problems perplexing a lot of crowds, are once formed, become the trouble of the mind into people. Existing restorative procedure mainly has the most several:
One, fruit acid changes skin method: the method uses high concentration fruit acid by striae gravidarum or the cutin of skin area skin Pull-up falls, and accelerates epidermis cell and the renewal of horn cell, thus improves striae gravidarum, cicatrix etc..But fruit Acid is changed skin and need to be carried out repeatedly, and therapeutic effect is the most thorough, it addition, the people of cutis laxa is also not suitable for fruit Skin method is changed in acid.
Two, photon delicate skin method: photon delicate skin method is to be made collagen fiber and the bullet of skin corium by longer wavelength Power fiber generation chemical change, promotes regenerated collagen fiber and rearranges, thus smoothing away wrinkles, reduce hair Hole.This method has certain effect to striae gravidarum, but striae gravidarum cannot be completely eliminated, and the method needs In regular cosmetic surgery hospital's operation, major part beauty parlor also has this project, but typically charge is prohibitively expensive.
Three, quintessence oil champignon method: the method use quintessence oil champignon be SPA help eliminate striae gravidarum, but this The method of kind can only desalinate striae gravidarum, and acts on extremely limited.
Four, surgery skin grafting method: being primarily directed in cicatrix, somebody takes surgery skin grafting, the method except Outside price is high, also there is certain surgical risk, be mainly used in the feelings of empyrosis degree especially severe Condition.
Five, mounted method of production: the method is to be attached on striae gravidarum, cicatrix with product as being similar to adhesive bandage, The most this product for cicatrix type the most limited, only Accretive Type cicatrix is had certain effect, meanwhile, Price is higher, and needs to reuse, the most unhygienic, and when using summer, easily come off or Person is to stop skin eupnea.
Six, being in from wound method: egg " facial film ", Ovum Gallus domesticus album thermal detoxification, desirable appropriate Ovum Gallus domesticus album uniformly applies pregnant It is pregnent at stricture of vagina, adds a little olive oil, massage of looping gently, wash away after ten minutes;Or Ovum Gallus domesticus album is applied Abdominal part, wraps with pure cotton cloth, continues 12 hours, has the effect of desalination convergence striae gravidarum;This kind of method effect Relatively slow, and need lasting considerable time.
Above-described removal striae gravidarum, the method for cicatrix, otherwise price is prohibitively expensive, brings sternly to patient The financial burden of weight, or the skin of patient or the type of cicatrix have been limited, some less effective, And troublesome poeration, bring inconvenience to patient.At present, for this present situation, also there are reparation striae gravidarum, scar The cosmetics of trace occur, but, existing cosmetics in use effect is unsatisfactory, and zest is strong, Skin-friendly is poor, and skin can be caused a certain degree of injury.
Summary of the invention:
The present invention is in order to make up the deficiencies in the prior art, it is provided that a kind of economical and practical, easy to use, infiltration Property is good, pro-skin is non-stimulated, play a role skin fanout free region, activity based on Sanguis Draxonis, the stimulating growth factor Repair cream without stricture of vagina and preparation method thereof, efficiently solve problems of the prior art.
The present invention solves that above-mentioned technical problem be the technical scheme is that
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following parts by weight:
Water 40-80 part, glycerol 2.5-4 part, butanediol 4-7 part, hydrolytic collagen 0.8-1.2 part, transparent Matter acid 0.1-0.5 part, pantothenylol 0.5-1 part, seed of Radix Oenotherae erythrosepalae extract 0.8-1.2 part, oligopeptide-1 are 0.8-1.2 Part, oligopeptide-2 are 0.8-1.2 part, trehalose 1.6-2.4 part, horse fat 4-6 part, Herba Centellae root extract 0.7-1.3 part, Europe Flos Caryophylli extract 1.3-1.8 part, ceteareth-10 are 1.7-2.3 part, whale Wax stearyl alcohol 1.3-1.8 part, Butyrospermum parkii fruit fatty oil 1.7-2.3 part, synthesis Jojoba oil 6.5-8.5 part, Sanguis Draxonis extract 2-5.5 part, allantoin 0.12-0.2 part, EDTA-2NA are 0.05 part, glycyrrhizic acid two Potassium 0.12-0.2 part, 1,2-pentanediol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, including following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 45-55min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 35-45min temperature extremely 80 DEG C obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 80-90 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 6-10min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 10-20min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, will in 40-50min The temperature of emulsifying pot is reduced to 55-65 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 50-60 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 10-20min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 20-26h up for safekeeping, to obtain final product.
The usage and dosage of repair cream without stricture of vagina of the present invention: before use, need to be cleaned skin with clear water, Use after body part in this way, the most handy warm water or shower.
Every day is the most each once, and by appropriate, without repairing, stricture of vagina is white to be dug out with little spoon, is coated directly on skin, presses Rub absorption about 1-3 minute.Face uses in this way, it is proposed that use after using cosmetic water.In this way Health uses, and the most i.e. can be used directly.Without cleaning after massage absorption.
The present invention is without the beneficial effect of stricture of vagina repair cream: the present invention without stricture of vagina repair cream all use natural component and in Herb ingredients, pro-skin is non-stimulated.Oligopeptide-1 and oligopeptide-2 its be active small molecular peptide, can directly be inhaled by skin Receive, promote reepithelialization and tissue in various kinds of cell growth division, make epidermis cell become full, Increasing fibrous elasticity, recover skin younger state, it also can promote the energy for growth of collagen protein, repairs old Change the collagen elastic fiber of fracture and downright bad cell tissue, make skin pattern color perfecting.Wherein oligopeptide-1 For hEGF, damaged skin, trauma skin and reconstruction skin are had good reparation, protects Reason effect, is especially adapted for use in nursing and the recovery of beautifying hand postoperative skin, have shortening the wound healing time and Reducing the effect of cicatrization, it can promote the metabolism of skin various types of cells, strengthens Skin Cell to battalion Support the absorption of material, slowing down skin aging, improve skin gloss, the synthesis of albumen, regulation in promotion skin The degraded of skin collagen and renewal, strengthen skin elasticity, reduces the formation of wrinkle of skin, smooths skin Existing microgroove, prevents and nurses acne.And oligopeptide-2 is the fibroblast growth factor of alkali components, it The microenvironment of cell growth can be improved, promote elastic fiber and the synthesis of collagen protein, make skin high resilience, Make skin be in lubricious state, and promote fibroblastic growth promoter, strengthen the metabolism of cell, Reduce the generation of wrinkle of skin, reduce melanin and the content of coloured corpuscle in Skin Cell, alleviate skin-color The deposition of element.Sanguis Draxonis extract, has another name called sanguis draconis or Sanguis Draxonis, has blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, convergence The remarkable efficacy such as hemostasis, hard masses softening and resolving and promoting tissue regeneration and ulcer healing.It can improve body microcirculation, adjust body the oldest Metabolism, improve body's immunity.Horse fat, permeability is strong, skin-friendly good, and it can promote other compositions Absorb, make skin smooth, contain unsaturated fatty acid and the vitamin of high-load simultaneously, there is moisturizing, Antiinflammatory is releived, antioxidative effect.Seed of Radix Oenotherae erythrosepalae extract, its energy endocrine regulation, improves wrinkle, promotees Enter skin health growth.Herba Centellae root extract, it have clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, anti-inflammation, Diuretic and spleen and effect of hemostasis and pain-relieving.Europe Flos Caryophylli extract, it can regulating QI and lowering the adverseness, warming middle-JIAO to relieve pain, warming the kidney, Easing pain and diminishing inflammation and treatment traumatic injury.Butyrospermum parkii fruit fatty oil, it is rich in anti-senility nutrient, can be to anti-ageing Always, prevent and treat mottle, improve skin elasticity, help to maintain skin emolliency with flexible.Hyaluronic acid, its tool There are lubricating joint, the permeability of regulation blood vessel wall, regulation protein, Water-Electrolyte diffusion and operating and promote The effects such as wound healing, it addition, hyaluronic acid has special water retention, are the natures having now been found that The material that middle moisture retention is best, is referred to as preferable nature moisturizing factor, can improve skin-nourishing metabolism, make Skin is tender, smooth, wrinkle removing, increase is elastic, prevent aging, is again good transdermal while moisturizing Absorption enhancer, it with other nutritional labelings with the use of, the ideal effect promoting alimentation can be played.、 Trehalose, it has heat clearing away, hard masses softening and resolving, antiinflammatory, effect of diuretic detumescent.
Detailed description of the invention:
Below in conjunction with embodiment, the invention will be further described, but the invention is not limited in this.
Embodiment 1:
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following weight:
Water 40g, glycerol 2.5g, butanediol 4g, hydrolytic collagen 0.8g, hyaluronic acid 0.1g, pantothenylol 0.5g, seed of Radix Oenotherae erythrosepalae extract 0.8g, oligopeptide-1 are 0.8g, oligopeptide-2 is 0.8g, trehalose 1.6 G, horse fat 4g, Herba Centellae root extract 0.7g, Europe Flos Caryophylli extract 1.3g, ceteareth-10 For 1.7g, cetearyl alcohol 1.3g, Butyrospermum parkii fruit fatty oil 1.7g, synthesis Jojoba oil 6.5g, Sanguis Draxonis extract 2g, allantoin 0.12g, EDTA-2NA are 0.05 part, glycyrrhizic acid dipotassium 0.12g, 1,2-pentanediol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, uses following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 45min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 35min temperature to 80 DEG C Obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 80 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 6min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 10min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, by emulsifying in 40min The temperature of pot is reduced to 55 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 50 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 10min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 20h up for safekeeping, to obtain final product.
Usage and dosage: before use, need to be cleaned skin with clear water, in this way body part, the most handy temperature Use after water or shower.
Every day is the most each once, and by appropriate, without repairing, stricture of vagina is white to be dug out with little spoon, is coated directly on skin, presses Rub absorption about 1-3 minute.Face uses in this way, it is proposed that use after using cosmetic water.In this way Health uses, and the most i.e. can be used directly.Without cleaning after massage absorption.
Embodiment 2:
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following weight:
Water 50g, glycerol 3g, butanediol 5g, hydrolytic collagen 0.9g, hyaluronic acid 0.2g, pantothenylol 0.6 G, seed of Radix Oenotherae erythrosepalae extract 0.9g, oligopeptide-1 are 0.9g, oligopeptide-2 is 0.9g, trehalose 1.8g, Horse fat 5g, Herba Centellae root extract 0.8g, Europe Flos Caryophylli extract 1.5g, ceteareth-10 For 1.8g, cetearyl alcohol 1.5g, Butyrospermum parkii fruit fatty oil 1.8g, synthesis Jojoba oil 7g, Qi Unicorn draconis extract 2.5g, allantoin 0.14g, EDTA-2NA are 0.05 part, glycyrrhizic acid dipotassium 0.14g, 1,2-pentanediol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, uses following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 48min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 38min temperature to 80 DEG C Obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 82 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 8min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 12min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, by emulsifying in 42min The temperature of pot is reduced to 58 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 53 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 12min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 22h up for safekeeping, to obtain final product.
Usage and dosage, with embodiment 1, the most no longer describes in detail.
Embodiment 3:
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following weight:
Water 60g, glycerol 3.5g, butanediol 5g, hydrolytic collagen 1.0g, hyaluronic acid 0.3g, pantothenylol 0.7g, seed of Radix Oenotherae erythrosepalae extract 1.0g, oligopeptide-1 are 1.0g, oligopeptide-2 is 1.0g, trehalose 2.0 G, horse fat 5g, Herba Centellae root extract 1.0g, Europe Flos Caryophylli extract 1.6g, ceteareth-10 For 2.0g, cetearyl alcohol 1.6g, Butyrospermum parkii fruit fatty oil 2.0g, synthesis Jojoba oil 7.5g, Qi Unicorn draconis extract 4g, allantoin 0.16g, EDTA-2NA are 0.05 part, glycyrrhizic acid dipotassium 0.16g, 1,2- Pentanediol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, uses following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 50min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 40min temperature to 80 DEG C Obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 85 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 8min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 15min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, by emulsifying in 45min The temperature of pot is reduced to 60 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 55 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 15min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 24h up for safekeeping, to obtain final product.
Usage and dosage, with embodiment 1, the most no longer describes in detail.
Embodiment 4:
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following weight:
Water 70g, glycerol 3.5g, butanediol 6g, hydrolytic collagen 1.1g, hyaluronic acid 0.4g, pantothenylol 0.8g, seed of Radix Oenotherae erythrosepalae extract 1.1g, oligopeptide-1 are 1.1g, oligopeptide-2 is 1.1g, trehalose 2.2 G, horse fat 5g, Herba Centellae root extract 1.2g, Europe Flos Caryophylli extract 1.7g, ceteareth-10 For 2.2g, cetearyl alcohol 1.7g, Butyrospermum parkii fruit fatty oil 2.2g, synthesis Jojoba oil 8g, kylin Draconis extract 5g, allantoin 0.18g, EDTA-2NA are 0.05 part, glycyrrhizic acid dipotassium 0.18g, 1,2- Pentanediol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, uses following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 52min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 42min temperature to 80 DEG C Obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 88 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 8min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 18min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, by emulsifying in 48min The temperature of pot is reduced to 62 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 58 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 18min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 24h up for safekeeping, to obtain final product.
Usage and dosage, with embodiment 1, the most no longer describes in detail.
Embodiment 5:
A kind of without stricture of vagina repair cream, its composition is made up of the raw material of following weight:
Water 80g, glycerol 4g, butanediol 7g, hydrolytic collagen 1.2g, hyaluronic acid 0.5g, pantothenylol 1g, Seed of Radix Oenotherae erythrosepalae extract 1.2g, oligopeptide-1 are 1.2g, oligopeptide-2 is 1.2g, trehalose 2.4g, horse fat 6g, Herba Centellae root extract 1.3g, Europe Flos Caryophylli extract 1.8g, ceteareth-10 are 2.3 G, cetearyl alcohol 1.8g, Butyrospermum parkii fruit fatty oil 2.3g, synthesis Jojoba oil 8.5g, Sanguis Draxonis carry Take thing 5.5g, allantoin 0.20g, EDTA-2NA are 0.05 part, glycyrrhizic acid dipotassium 0.20g, 1,2-penta Glycol 0.01 part.
A kind of method preparing above-mentioned repair cream without stricture of vagina, uses following operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 55min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 45min temperature to 80 DEG C Obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 90 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 10min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 20min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, by emulsifying in 50min The temperature of pot is reduced to 65 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 60 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 20min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 26h up for safekeeping, to obtain final product.
Usage and dosage, with embodiment 1, the most no longer describes in detail.

Claims (2)

1. one kind without stricture of vagina repair cream, it is characterised in that: its composition is made up of the raw material of following parts by weight:
Water 40-80 part, glycerol 2.5-4 part, butanediol 4-7 part, hydrolytic collagen 0.8-1.2 part, transparent Matter acid 0.1-0.5 part, pantothenylol 0.5-1 part, seed of Radix Oenotherae erythrosepalae extract 0.8-1.2 part, oligopeptide-1 are 0.8-1.2 Part, oligopeptide-2 are 0.8-1.2 part, trehalose 1.6-2.4 part, horse fat 4-6 part, Herba Centellae root extract 0.7-1.3 part, Europe Flos Caryophylli extract 1.3-1.8 part, ceteareth-10 are 1.7-2.3 part, whale Wax stearyl alcohol 1.3-1.8 part, Butyrospermum parkii fruit fatty oil 1.7-2.3 part, synthesis Jojoba oil 6.5-8.5 part, Sanguis Draxonis extract 2-5.5 part, allantoin 0.12-0.2 part, EDTA-2NA are 0.05 part, glycyrrhizic acid two Potassium 0.12-0.2 part, 1,2-pentanediol 0.01 part.
2. the preparation method of a repair cream without stricture of vagina as claimed in claim 1, it is characterised in that: include as Lower operating procedure:
A, take the water of above-mentioned parts by weight, glycerol, butanediol, allantoin, EDTA-2NA are sequentially added into water Mixed liquor A is obtained in Guo and when heating 45-55min, temperature to 80 DEG C;
B, take the Radix Oenotherae erythrosepalae of above-mentioned parts by weight, horse fat, ceteareth-10, cetearyl alcohol, Butyrospermum parkii fruit fatty oil, synthesis Jojoba oil are sequentially added in oil cauldron and heat 35-45min temperature extremely 80 DEG C obtain mixed liquid B;
C, by emulsifying pot evacuation and make its vacuum maintain 0.06Pa, open emulsifying pot heat button simultaneously, Heat to emulsifying pot;
D, the mixed liquor A in step a being the most slowly pumped in emulsifying pot, constant temperature keeps breast Change the temperature in pot at 80-90 DEG C;
E, the mixed liquid B in step b is slowly pumped into mixing speed in the emulsifying pot of 20/min;Permanent Temperature keeps the temperature in emulsifying pot at 85 DEG C, opens homogenizer button, homogenizing under 10r/min mixing speed Stirring 6-10min;
F, 85 DEG C of constant temperature, 25r/min mixing speed under stir 10-20min;
G, unlatching cooling water, and control to cool down the speed of water, cool down while stirring, will in 40-50min The temperature of emulsifying pot is reduced to 55-65 DEG C;
H, take the hydrolytic collagen of above-mentioned parts by weight, hyaluronic acid and trehalose and be dissolved completely in ionized water Mixed liquor C;
I, being slowly added in emulsifying pot by mixed liquor C, be then turned on vacuum buttons, make in emulsifying pot is true Reciprocal of duty cycle is maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to 50-60 DEG C;
J, the pantothenylol taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot be maintained at 0.06Pa;Stirring makes the temperature in emulsifying pot be reduced to less than 50 DEG C;
K, take the oligopeptide-1 of above-mentioned parts by weight, oligopeptide-2, Herba Centellae root extract, Europe Flos Caryophylli extract and Sanguis Draxonis extract joins in emulsifying pot, and makes the vacuum in emulsifying pot be maintained at 0.06Pa;
L, the glycyrrhizic acid dipotassium taking above-mentioned parts by weight join in emulsifying pot, and make the vacuum in emulsifying pot It is maintained at 0.06Pa;
M, add the 1 of above-mentioned parts by weight when the temperature in emulsifying pot is reduced to 40 DEG C, 2-pentanediol, and The vacuum in emulsifying pot is made to be maintained at 0.06Pa;Mixed liquor is obtained after stirring 10-20min;
N, the mixed liquor in step m is placed in sterilization container, applies preservative film, seal 20-26h up for safekeeping, to obtain final product.
CN201610237067.6A 2016-04-15 2016-04-15 Wrinkle-free repair cream and preparation method thereof Pending CN105816377A (en)

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CN106691917A (en) * 2016-11-26 2017-05-24 无锡市汉方八珍科技有限公司 Pearl and cortex eucommiae repair cream and preparation method thereof
CN106860148A (en) * 2017-02-17 2017-06-20 张策 A kind of striae of pregnancy repair cream and preparation method thereof
CN107050114A (en) * 2017-04-28 2017-08-18 防城港市动物疫病预防控制中心 A kind of anthelmintic for animals and preparation method thereof
CN107213275A (en) * 2017-04-28 2017-09-29 防城港市畜牧站 A kind of raise livestock anthelmintic and preparation method thereof
CN107441032A (en) * 2017-09-28 2017-12-08 深圳市天香赋生物科技有限公司 A kind of agalloch eaglewood plant is compacted the preparation method of repair cream
CN107595737A (en) * 2017-09-20 2018-01-19 嘉文丽(福建)化妆品有限公司 The composition of whitening anti-wrinkling containing Antrodia camphorata and Essence and the preparation method of Essence containing said composition
CN108524318A (en) * 2017-03-02 2018-09-14 广州微肽生物科技有限公司 Polypeptide reparative factor ice crystal
CN110051587A (en) * 2019-05-04 2019-07-26 广州市爱百伊生物技术有限公司 A kind of preparation method and application of the anti-apolexis composition containing a variety of sodium hyaluronates
CN110935097A (en) * 2019-12-03 2020-03-31 广州新济薇娜生物科技有限公司 Microneedle patch for improving skin hypertrophic scar and preparation method thereof
CN111000767A (en) * 2019-12-19 2020-04-14 郑远元 Chitosan nano moisturizing repair liquid for feet and preparation method thereof
CN111388650A (en) * 2020-04-10 2020-07-10 深圳市容大生物技术有限公司 Composition for balancing male hormone and enhancing male charm and preparation method thereof
CN112043659A (en) * 2020-09-27 2020-12-08 广州保龄奇迹化妆品科技有限公司 Anti-wrinkle repair essence cream
CN113116771A (en) * 2021-02-24 2021-07-16 湖北研妆实业有限公司 Repairing type water-replenishing horse oil cream and preparation method thereof

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691917A (en) * 2016-11-26 2017-05-24 无锡市汉方八珍科技有限公司 Pearl and cortex eucommiae repair cream and preparation method thereof
CN106860148A (en) * 2017-02-17 2017-06-20 张策 A kind of striae of pregnancy repair cream and preparation method thereof
CN106860148B (en) * 2017-02-17 2018-01-02 邓家松 A kind of striae of pregnancy repair cream and preparation method thereof
CN108524318A (en) * 2017-03-02 2018-09-14 广州微肽生物科技有限公司 Polypeptide reparative factor ice crystal
CN107050114A (en) * 2017-04-28 2017-08-18 防城港市动物疫病预防控制中心 A kind of anthelmintic for animals and preparation method thereof
CN107213275A (en) * 2017-04-28 2017-09-29 防城港市畜牧站 A kind of raise livestock anthelmintic and preparation method thereof
CN107595737B (en) * 2017-09-20 2020-08-25 嘉文丽(福建)化妆品有限公司 Whitening and anti-wrinkle composition containing antrodia camphorata, essence containing composition and preparation method of essence
CN107595737A (en) * 2017-09-20 2018-01-19 嘉文丽(福建)化妆品有限公司 The composition of whitening anti-wrinkling containing Antrodia camphorata and Essence and the preparation method of Essence containing said composition
CN107441032A (en) * 2017-09-28 2017-12-08 深圳市天香赋生物科技有限公司 A kind of agalloch eaglewood plant is compacted the preparation method of repair cream
CN110051587A (en) * 2019-05-04 2019-07-26 广州市爱百伊生物技术有限公司 A kind of preparation method and application of the anti-apolexis composition containing a variety of sodium hyaluronates
CN110935097A (en) * 2019-12-03 2020-03-31 广州新济薇娜生物科技有限公司 Microneedle patch for improving skin hypertrophic scar and preparation method thereof
CN110935097B (en) * 2019-12-03 2021-10-29 广州新济薇娜生物科技有限公司 Microneedle patch for improving skin hypertrophic scar and preparation method thereof
CN111000767A (en) * 2019-12-19 2020-04-14 郑远元 Chitosan nano moisturizing repair liquid for feet and preparation method thereof
CN111388650A (en) * 2020-04-10 2020-07-10 深圳市容大生物技术有限公司 Composition for balancing male hormone and enhancing male charm and preparation method thereof
CN112043659A (en) * 2020-09-27 2020-12-08 广州保龄奇迹化妆品科技有限公司 Anti-wrinkle repair essence cream
CN113116771A (en) * 2021-02-24 2021-07-16 湖北研妆实业有限公司 Repairing type water-replenishing horse oil cream and preparation method thereof
CN113116771B (en) * 2021-02-24 2022-07-22 湖北研妆实业有限公司 Repairing type water replenishing horse oil cream and preparation method thereof

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