CN105726400A - Preparation method of whitening and skincare biological dressings - Google Patents
Preparation method of whitening and skincare biological dressings Download PDFInfo
- Publication number
- CN105726400A CN105726400A CN201610140677.4A CN201610140677A CN105726400A CN 105726400 A CN105726400 A CN 105726400A CN 201610140677 A CN201610140677 A CN 201610140677A CN 105726400 A CN105726400 A CN 105726400A
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- preparation
- skin
- whitening
- alginate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0204—Specific forms not provided for by any of groups A61K8/0208 - A61K8/14
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses a preparation method of whitening and skincare biological dressings.The preparation method includes: weighing raw materials according to the weight, well mixing in a reactor, and heating; pouring the evenly-mixed mixture into a film-making die, flattening through scraping, sufficiently drying, and removing the die to obtain a medicine-stored layer; compositing the medicine-stored layer with base cloth through binder, and using an intensive-puncturing micro-pore machine to puncture the composite material; cutting the punctured composite material into required shapes, and sealing and sterilizing to obtain the biological dressings.The biological dressings prepared by the method have the advantages that the biological dressings made of traditional Chinese medicine materials are low in irritation, free of toxic and side effects and good in biocompatibility; by the reasonable combination of the traditional Chinese medicine materials, the biological dressings can effectively prevent the generation of melanin, reduce and decompose existing melanin, activate cells, fade freckles on the face, repair skin damage caused by chemical components such as hormone, whiten and moisturize the skin, and allow the skin to be glossy and fine and smooth.
Description
Technical field
The invention belongs to medical bio field of new, the preparation method relating to a kind of whitening and skin-protecting biological dressing.
Technical background
Everybody has a love of beauty, and along with improving constantly of people's living standard, beautiful pursuit is also improved constantly by people, for most of women, is intended to change the appearance of oneself and have the pale colour of skin.But, for women, with advancing age, the metabolism of health slows down, add life anxiety, work and rest irregular, and various environmental pollution, cause that self-resistance declines, endocrine disturbance, makes interior free yl activate, and skin becomes intensely dark pool.Especially for the women that some born skins are partially black, whitening their unremitting pursuit especially.And with advancing age, women skin quality also worse and worse, becomes coarse, oneself more seeming young to allow, many women, for the more smooth exquisiteness of skin, adopt the mode playing hormone pin, and health is had bigger side effect by this mode, it is easy to cause endocrine disturbance.But current beauty industry is extremely complex, both advantageous and disadvantageous, many times, all can hear that some thus result in some cureless final results because of the former of cosmetics.At present, the method commonly used in beauty industry includes therapeutic method of surgery, drug treatment and outer coating method.But operative treatment is not appropriate for for many patients, has a big risk；Pharmacotherapy, including oral medicine and medicine for external use, also ubiquity effect not significantly shortcoming.And outer coating method is simple to operation and the injury of patient is minimum, therefore, increasing consumer pays close attention to outer coating method.
Biological dressing is the Novel wound reparation and protection material that grow up in repair in trauma " moistening healing " theoretical basis proposed such as Winter.Compared with traditional dressing, biological dressing has reduction and infects, improves wound healing quality, alleviate the misery of patient and facilitate the advantages such as medical personnel's operation, therefore obtains the favor of people.But also little for the dressing of Firm speckle dispelling on the market at present, it is almost blank.In view of this, it is necessary to the dressing of a kind of skin problem that effectively can effectively solve the dim coarse initiation of skin is provided.
Summary of the invention
Present invention aims to the deficiencies in the prior art, it is provided that the preparation method of a kind of whitening and skin-protecting biological dressing.
It is an object of the invention to be achieved through the following technical solutions: the preparation method of a kind of whitening and skin-protecting biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 60-70 part, poly hexamethylene guanidine derivative 8-12 part, Heveatex 3-10 part, alginate 3-12 part, glycerol 13-17 part, Aloe powder 5-8 part, Radix Angelicae Dahuricae powder 3-4 part, Herba Salviae Japonicae essential oil 10-14 part, glycyrrhizic acid dipotassium 6-10 part, hyaluronate sodium 10-14 part, emulsifying agent 3-10 part, plasticizer 3-10 part, cross-linking agent 10-14 part and water 30-40 part are placed in after stirring in reactor, it is heated to 65 ~ 70 DEG C, heat time heating time is 15 ~ 25min；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Biological dressing prepared by the method by the present invention that the method have the advantages that adopts Chinese medicine formula, and zest is little, has no side effect, and not easily recurs, and has good biocompatibility.By rational compatibility, the basal layer that the whitening and skin-protecting dressing prepared can not only penetrate to the skin effectively, and can effectively suppress the activity of tryrosinase, efficient scavenging activated oxygen, prevent melanic generation, the existing melanin of reduction decomposition simultaneously, activating cell, desalination face speckle, gradually chloasma is eliminated, butterfly spot, the skin problem that the pigmentations such as senile plaque cause, repair the damage owing to skin is caused by the chemical compositions such as hormone simultaneously, thus reaching comprehensively quickly, the effect for the treatment of both the principal and secondary aspects of a disease, make skin-whitening, moisten moisturizing, gloss is fine and smooth.
Detailed description of the invention
Embodiment 1
A kind of preparation method of whitening and skin-protecting biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 60 parts, poly hexamethylene guanidine derivative 8 parts, Heveatex 3 parts, alginate 3 parts, glycerol 13 parts, Aloe powder 5 parts, 3 parts of Radix Angelicae Dahuricae powder, Herba Salviae Japonicae essential oil 10 parts, glycyrrhizic acid dipotassium 6 parts, hyaluronate sodium 10 parts, emulsifying agent 3 parts, plasticizer 3 parts, cross-linking agent 10 parts and 30 parts of water to be placed in after reactor stirs, being heated to 65 ~ 70 DEG C, heat time heating time is 15 ~ 25min；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Embodiment 2
A kind of preparation method of whitening and skin-protecting biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 70 parts, poly hexamethylene guanidine derivative 12 parts, Heveatex 10 parts, alginate 12 parts, glycerol 17 parts, Aloe powder 8 parts, 4 parts of Radix Angelicae Dahuricae powder, Herba Salviae Japonicae essential oil 14 parts, glycyrrhizic acid dipotassium 10 parts, hyaluronate sodium 14 parts, emulsifying agent 10 parts, plasticizer 10 parts, cross-linking agent 14 parts and 40 parts of water to be placed in after reactor stirs, being heated to 65 ~ 70 DEG C, heat time heating time is 15 ~ 25min；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Embodiment 3
A kind of preparation method of whitening and skin-protecting biological dressing, this preparation method comprises the following steps: by weight, weigh chitosan 65 parts, poly hexamethylene guanidine derivative 11 parts, Heveatex 6 parts, alginate 7 parts, glycerol 15 parts, Aloe powder 7 parts, 3 parts of Radix Angelicae Dahuricae powder, Herba Salviae Japonicae essential oil 12 parts, glycyrrhizic acid dipotassium 8 parts, hyaluronate sodium 12 parts, emulsifying agent 6 parts, plasticizer 6 parts, cross-linking agent 12 parts and 35 parts of water to be placed in after reactor stirs, being heated to 65 ~ 70 DEG C, heat time heating time is 15 ~ 25min；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
Described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
Described binding agent is pressure sensitive adhesive.
Described alginate is potassium alginate, sodium alginate or calcium alginate.
Described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Claims (5)
1. the preparation method of a whitening and skin-protecting biological dressing, it is characterized in that this preparation method comprises the following steps: by weight, weigh chitosan 60-70 part, poly hexamethylene guanidine derivative 8-12 part, Heveatex 3-10 part, alginate 3-12 part, glycerol 13-17 part, Aloe powder 5-8 part, Radix Angelicae Dahuricae powder 3-4 part, Herba Salviae Japonicae essential oil 10-14 part, glycyrrhizic acid dipotassium 6-10 part, hyaluronate sodium 10-14 part, emulsifying agent 3-10 part, plasticizer 3-10 part, cross-linking agent 10-14 part and water 30-40 part are placed in after stirring in reactor, it is heated to 65 ~ 70 DEG C, heat time heating time is 15 ~ 25min；Mixture after heating is poured on masking mould, strikes off, dry after fully, demoulding, prepare drug storing layer；Finally the drug storing layer prepared and base fabric are passed through the bonding compound of binding agent, utilize intensive acupuncture Micro hole machine to be punched by adhesive composite materials；Intensive composite after punching is cut into required form, seals sterilizing.
2. the preparation method of a kind of whitening and skin-protecting biological dressing according to claim 1, it is characterised in that: described base cloth layer is non-woven fabrics or PU waterproof ventilated membrane.
3. the preparation method of a kind of whitening and skin-protecting biological dressing according to claim 1, it is characterised in that: described binding agent is pressure sensitive adhesive.
4. the preparation method of a kind of whitening and skin-protecting biological dressing according to claim 1, it is characterised in that: described alginate is potassium alginate, sodium alginate or calcium alginate.
5. the preparation method of a kind of whitening and skin-protecting biological dressing according to claim 1, it is characterised in that: described emulsifying agent is stearic acid list glyceride or sodium lauryl sulphate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610140677.4A CN105726400A (en) | 2016-03-14 | 2016-03-14 | Preparation method of whitening and skincare biological dressings |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610140677.4A CN105726400A (en) | 2016-03-14 | 2016-03-14 | Preparation method of whitening and skincare biological dressings |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105726400A true CN105726400A (en) | 2016-07-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610140677.4A Pending CN105726400A (en) | 2016-03-14 | 2016-03-14 | Preparation method of whitening and skincare biological dressings |
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| CN (1) | CN105726400A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108771644A (en) * | 2018-08-27 | 2018-11-09 | 铜仁学院 | A kind of application of alginic acid/sodium alginate as tyrosinase inhibitor |
| CN109316418A (en) * | 2018-11-01 | 2019-02-12 | 壹鼎众康(厦门)生物科技股份有限公司 | A kind of alginate antibacterial gel and its processing technology |
| CN109700741A (en) * | 2019-03-06 | 2019-05-03 | 桂林电子科技大学 | A kind of persimmon tannin composite material and its application in ionizing radiation-resistant |
| CN110755342A (en) * | 2019-10-08 | 2020-02-07 | 甘肃锦东健康科技有限公司 | Anti-aging medical biological repair dressing containing traditional Chinese medicine microcapsule powder and preparation method thereof |
-
2016
- 2016-03-14 CN CN201610140677.4A patent/CN105726400A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108771644A (en) * | 2018-08-27 | 2018-11-09 | 铜仁学院 | A kind of application of alginic acid/sodium alginate as tyrosinase inhibitor |
| CN108771644B (en) * | 2018-08-27 | 2021-03-16 | 铜仁学院 | Application of alginic acid/sodium alginate as tyrosinase inhibitor |
| CN109316418A (en) * | 2018-11-01 | 2019-02-12 | 壹鼎众康(厦门)生物科技股份有限公司 | A kind of alginate antibacterial gel and its processing technology |
| CN109700741A (en) * | 2019-03-06 | 2019-05-03 | 桂林电子科技大学 | A kind of persimmon tannin composite material and its application in ionizing radiation-resistant |
| CN110755342A (en) * | 2019-10-08 | 2020-02-07 | 甘肃锦东健康科技有限公司 | Anti-aging medical biological repair dressing containing traditional Chinese medicine microcapsule powder and preparation method thereof |
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| C06 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160706 |
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| RJ01 | Rejection of invention patent application after publication |