CN105685526A - Chinese herbal medicine anti-disease immune feed additive for shrimps and preparation method of Chinese herbal medicine anti-disease immune feed additive - Google Patents
Chinese herbal medicine anti-disease immune feed additive for shrimps and preparation method of Chinese herbal medicine anti-disease immune feed additive Download PDFInfo
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- CN105685526A CN105685526A CN201610037299.7A CN201610037299A CN105685526A CN 105685526 A CN105685526 A CN 105685526A CN 201610037299 A CN201610037299 A CN 201610037299A CN 105685526 A CN105685526 A CN 105685526A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Abstract
The invention discloses a Chinese herbal medicine anti-disease immune feed additive for shrimps. The Chinese herbal medicine anti-disease immune feed additive is prepared from the following raw materials in parts by weight: 5 to 25 parts of radix astragali seu hedysari, 5 to 25 parts of radix isatidis, 5 to 25 parts of radix bupleuri, 5 to 15 parts of flos lonicerae, 5 to 15 parts of radix scutellariae, 5 to 10 parts of Chinese angelic, 5 to 10 parts of radix glycyrrhizae, 5 to 10 parts of poria cocos, 2 to 10 parts of tangerine peel, 2 to 10 parts of fructus crataegi, 3 to 5 parts of a binding agent, 8 to 10 parts of a disintegrating agent and 3 to 5 parts of a moisture absorbent. The invention further discloses a preparation method of the Chinese herbal medicine anti-disease immune feed additive for the shrimps. The preparation method comprises the following steps: step 1, carrying out ultrafine powder crushing; step 2, mixing ultrafine powder with feed, and adding water to prepare paste; step 3, spraying and drying; step 4, adding a binding agent solution and blending, and granulating; step 5, drying at the temperature lower than 60 DEG C and granulating; adding the disintegrating agent and the moisture absorbent in parts by weight, and uniformly mixing; pressing the mixture into sheets according to the weight specification of 5 grams per tablet. By adopting the Chinese herbal medicine anti-disease immune feed additive for the shrimps, the growth performance of the shrimps can be obviously promoted, the immune function and the capability of resisting white spot syndrome viruses of the shrimps are improved, and the survival rate in a shrimp culture period is improved.
Description
Technical field
The present invention relates to the technical field of feedstuff, particularly relate to seed shrimp Chinese herbal medicine disease-resistant immunological feed additive and preparation method thereof。
Background technology
Litopenaeus vannamei (Litopenaeusvannamei) is commonly called as Penaeus vannamei, is one of big shrimps in culture kind in the world three。Owing to growing rapid, strong stress resistance, dressing percentage high density high, resistance to and low salinity stocking so that this seed shrimp cultured output accounts for more than the 80% of shrimps total output, becomes the prawn culturing kind that China is main。Along with the deterioration of constantly the expanding of shrimp aquaculture scale, the raising of intensive degree and prawn living environment, the extent of injury of disease is increasing。Particularly white spot syndrome virus (WSSV) (whitespotsyndromevirus, WSSV), is endanger a kind of prawn ' s virus the most serious up to now, and in infection shrimp 7d-10d, mortality rate is up to 80%-100%。Breeding production adopts antibiotic and other chemical classes medicines prevent and treat, it is easy to the ecological balance interdepend between broken biological, mutually restricted, it is suppressed that the breeding of beneficial algae, even have drug residue, brought serious consequence to prawn healthy aquaculture。Chinese herbal medicine have natural, efficient, toxic and side effects is little, be not likely to produce the features such as Drug resistance, and the existing antibacterial action of some composition in medicine, there is again immunization, the immune state of body can be improved, improving the advantages such as self resistance against diseases, most raw materials are Green Product。
Chinese herbal feed additive application in aquatic feeds has many reports both at home and abroad。But the material in anti-WSSV is comparatively fragmentary, lack systematicness, all extremely complex plus Chinese medicine mechanism and water environment, do not use Chinese materia medica, pharmaceutics, pharmacological principle studies the aquatic animal of comparatively low grade targetedly, also the collaborative or antagonism between each composition is seldom considered, therefore current prawn Chinese herbal feed additive remains many weak points, such as form more complicated, materials and processing are all cumbersome, poor at water stability, Expected Results is unstable, addition in feedstuff is too high, both cost had been increased, it is unfavorable for again application, what have also produces impact to the palatability of feedstuff。
In view of this, the present inventor studies and devises seed shrimp Chinese herbal medicine disease-resistant immunological feed additive and preparation method thereof, and this case thus produces。
Summary of the invention
It is an object of the invention to provide seed shrimp Chinese herbal medicine disease-resistant immunological feed additive and preparation method thereof, to solve the deficiencies in the prior art, and then provide scientific formulation, stability is strong, good palatability, can be effectively improved the survival rate of prawn, reduces the feed additive of feeding cost。
To achieve these goals, this invention address that its technical problem is adopted the technical scheme that:
One seed shrimp Chinese herbal medicine disease-resistant immunological feed additive, is made up of the raw material of following weight proportion:
Radix Astragali 5-25 part, Radix Isatidis 5-25 part, Radix Bupleuri 5-25 part, Flos Lonicerae 5-15 part, Radix Scutellariae 5-15 part, Radix Angelicae Sinensis 5-10 part, Radix Glycyrrhizae 5-10 part, Poria 5-10 part, Pericarpium Citri Reticulatae 2-10 part, Fructus Crataegi 2-10 part, binding agent 3-5 part, disintegrating agent 8-10 part and hygroscopic agent 3-5 part。
As the optimal way of embodiment, the Radix Astragali 8 parts, Radix Isatidis 10 parts, Radix Bupleuri 18 parts, Flos Lonicerae 12 parts, Radix Scutellariae 12 parts, Radix Angelicae Sinensis 8 parts, 7 parts of Radix Glycyrrhizae, 8 parts of Poria, Pericarpium Citri Reticulatae 5 parts and Fructus Crataegi 8 parts。
As the optimal way of embodiment, described binding agent is one or more in polyvinylpolypyrrolidone, hydroxypropyl methyl cellulose, dextrin, microcrystalline Cellulose, starch slurry, sodium carboxymethyl cellulose, hydroxypropyl cellulose, methylcellulose, ethyl cellulose, gelatin, sucrose, polyvinylpyrrolidone。
As the optimal way of embodiment, described disintegrating agent is one or more in carboxymethyl starch sodium, dried starch, low-substituted hydroxypropyl cellulose, crospolyvinylpyrrolidone, cross-linking sodium carboxymethyl cellulose。
As the optimal way of embodiment, described hygroscopic agent is one or more of calcium oxide, magnesium oxide, aluminium oxide, anhydrous cupric sulfate and silica gel。
The one seed shrimp preparation method of Chinese herbal medicine disease-resistant immunological feed additive, comprises the following steps:
Step one, weigh the raw material of described parts by weight, adopt that superfine powder is broken is ground into ultra-fine 100 order particle size powders additives；
Step 2, weigh the feedstuff of above-mentioned 1 part of powder additive and 50-200 part, make compound, add water and prepare into serosity according to weight ratio 1:1 mixing；
Step 3, above-mentioned serosity is pumped into spraying pressurized nozzles be sprayed in spray drying tower and carry out less than 60 DEG C atomization dryings become feed particulate material；
Step 4, taking above-mentioned feed particulate material, the binder solution adding concentration 10-15% is in harmonious proportion, and granulates；
Step 5, through less than 60 DEG C dry, granulate, be separately added into disintegrating agent and the hygroscopic agent of described parts by weight, mixing, according to 5g/ sheet weight specification tabletted。
As the optimal way of embodiment, described feedstuff is made up of the raw material of following parts by weight: shrimp crack 35-50 part, breaking cellular wall yeast 2-3 part, ocean rhodotorula 2-3 part, astaxanthin 0.1-0.5 part, vitamin D3 0.3-0.8 part, soluble calcium salt 2-4 part, binding agent 3-5 part, disintegrating agent 8-10 part and hygroscopic agent 3-5 part。
Compared with prior art, present invention have the advantage that (1) uses in prawn mixed feed as feed additive, addition is only 0.5%-2.5%；(2) prawn digestive organs digestive enzyme activity can be significantly improved, promote that prawn digests and assimilates and grows；(3) strengthen immunity of organism and the premunition of prawn, improve survival rate；(4) present invention for the palatability of prawn mixed feed without any harmful effect；(5) raw material of the present invention abundance at home, price steadiness is cheap；(6) micronizing, particle diameter is less, it is easier to digested and assimilated by prawn, and production and processing technology is simple。
Detailed description of the invention
Embodiment 1
One seed shrimp Chinese herbal medicine disease-resistant immunological feed additive, is made up of the raw material of following weight proportion:
The Radix Astragali 5 parts, Radix Isatidis 5 parts, Radix Bupleuri 5 parts, Flos Lonicerae 5 parts, Radix Scutellariae 5 parts, Radix Angelicae Sinensis 5 parts, 5 parts of Radix Glycyrrhizae, 5 parts of Poria, Pericarpium Citri Reticulatae 2 parts, Fructus Crataegi 2 parts, binding agent 3 parts, disintegrating agent 8 parts and hygroscopic agent 3 parts。
Embodiment 2
One seed shrimp Chinese herbal medicine disease-resistant immunological feed additive, is made up of the raw material of following weight proportion:
The Radix Astragali 8 parts, Radix Isatidis 10 parts, Radix Bupleuri 18 parts, Flos Lonicerae 12 parts, Radix Scutellariae 12 parts, Radix Angelicae Sinensis 8 parts, 7 parts of Radix Glycyrrhizae, 8 parts of Poria, Pericarpium Citri Reticulatae 5 parts and Fructus Crataegi 8 parts。
Embodiment 3
One seed shrimp Chinese herbal medicine disease-resistant immunological feed additive, is made up of the raw material of following weight proportion:
The Radix Astragali 25 parts, Radix Isatidis 25 parts, Radix Bupleuri 25 parts, Flos Lonicerae 15 parts, Radix Scutellariae 15 parts, Radix Angelicae Sinensis 10 parts, 10 parts of Radix Glycyrrhizae, 10 parts of Poria, Pericarpium Citri Reticulatae 10 parts, Fructus Crataegi 10 parts, binding agent 5 parts, disintegrating agent 10 parts and hygroscopic agent 5 parts。
As the optimal way of embodiment 1-3, described binding agent is one or more in polyvinylpolypyrrolidone, hydroxypropyl methyl cellulose, dextrin, microcrystalline Cellulose, starch slurry, sodium carboxymethyl cellulose, hydroxypropyl cellulose, methylcellulose, ethyl cellulose, gelatin, sucrose, polyvinylpyrrolidone。
As the optimal way of embodiment 1-3, described disintegrating agent is one or more in carboxymethyl starch sodium, dried starch, low-substituted hydroxypropyl cellulose, crospolyvinylpyrrolidone, cross-linking sodium carboxymethyl cellulose。
As the optimal way of embodiment 1-3, described hygroscopic agent is one or more of calcium oxide, magnesium oxide, aluminium oxide, anhydrous cupric sulfate and silica gel。
Embodiment 4
The one seed shrimp preparation method of Chinese herbal medicine disease-resistant immunological feed additive, comprises the following steps:
Step one, weigh the raw material of described parts by weight, adopt that superfine powder is broken is ground into ultra-fine 100 order particle size powders additives；
Step 2, weigh the feedstuff of above-mentioned 1 part of powder additive and 50-200 part, make compound, add water and prepare into serosity according to weight ratio 1:1 mixing；
Step 3, above-mentioned serosity is pumped into spraying pressurized nozzles be sprayed in spray drying tower and carry out less than 60 DEG C atomization dryings become feed particulate material；
Step 4, taking above-mentioned feed particulate material, the binder solution adding concentration 10-15% is in harmonious proportion, and granulates；
Step 5, through less than 60 DEG C dry, granulate, be separately added into disintegrating agent and the hygroscopic agent of described parts by weight, mixing, according to 5g/ sheet weight specification tabletted。
As the optimal way of embodiment, described feedstuff is made up of the raw material of following parts by weight: shrimp crack 35-50 part, breaking cellular wall yeast 2-3 part, ocean rhodotorula 2-3 part, astaxanthin 0.1-0.5 part, vitamin D3 0.3-0.8 part, soluble calcium salt 2-4 part, binding agent 3-5 part, disintegrating agent 8-10 part and hygroscopic agent 3-5 part。
Experimental example 5
1, experimental design
Choose average body length (1.37 ± 0.05) cm, Litopenaeus vannamei 1800 tail of weight (0.12 ± 0.03) g, it is randomly divided into 6 groups, often 3 repetitions of group, each Glass fibre reinforced plastic tub (500L) puts 100 tails in a suitable place to breed, respectively matched group (0%), experimental group 1, experimental group 2, experimental group 3, experimental group 4 and experimental group 5。
2, experiment feedstuff
Matched group selects common prawn feed；Experimental group 1 adds the Chinese herbal medicine disease-resistant immunological feed additive of the present invention of 0.5% on the basis of common prawn feed；Experimental group 2 adds the Chinese herbal medicine disease-resistant immunological feed additive of the present invention of 1.0% on the basis of common prawn feed；Experimental group 3 is also added with the Chinese herbal medicine disease-resistant immunological feed additive of the present invention of 1.5% on the basis of common prawn feed；Experimental group 4 adds the Chinese herbal medicine disease-resistant immunological feed additive of the present invention of 2.0% on the basis of common prawn feed；Experimental group 5 is also added with the Chinese herbal medicine disease-resistant immunological feed additive of the present invention of 2.5% on the basis of common prawn feed。
3, feeding and management and index determining
Every natural gift 7:00, three feedstuffs of throwing something and feeding of 13:00 and 19:00, within during cultivation every 2 days, change water once, adopt natural temperature (26～31 DEG C), seawater salinity is 25 ± 2mg/L, the continuous oxygenation of whole process, experimental period is 30d, the detection growth performance of prawn, digestive enzyme activity and immunological characteristic。
The impact on prawn growth, digestive enzyme activity and immunity of the table 1 Chinese herbal medicine disease-resistant immunological feed additive
As shown in Table 1, the growth of prawn, survival, digestive enzyme activity and immune indexes are all significantly improved by the feedstuff adding Chinese herbal medicine disease-resistant immunological feed additive of the present invention, substantially increase prawn survival rate and prawn body weight。Specific growth rate improves 7.9%～25.6% than matched group, reduces feed coefficient 0.08～0.24, and survival rate improves 6.05%～14.12%。
After off-test, randomly draw 30 tails (often group 3 barrels) for every barrel, throw something and feed and infect the fresh sick shrimp of WSSV after testing, mince and throw something and feed by body weight 5～10%, normally throw something and feed every day, soil pick-up, change water, the active situation of regular check shrimp, collect in time, numbering, calculate survival rate。
The impact on the anti-WSSV of Litopenaeus vannamei of the table 2 medical herbs anti pathologic immunity feed additive
As shown in Table 2, after infection experiment, experimental group semilethal (50%) Time transfer receiver is according to group prolongation 23.8～47.6h；Survival rate improves 3.34%～10.00% than matched group。All deformation that those of ordinary skill in the art can directly derive from the disclosure of invention or associate, are all considered as protection scope of the present invention。
Claims (7)
1. seed shrimp Chinese herbal medicine disease-resistant immunological feed additive, it is characterised in that: it is made up of the raw material of following weight proportion:
Radix Astragali 5-25 part, Radix Isatidis 5-25 part, Radix Bupleuri 5-25 part, Flos Lonicerae 5-15 part, Radix Scutellariae 5-15 part, Radix Angelicae Sinensis 5-10 part, Radix Glycyrrhizae 5-10 part, Poria 5-10 part, Pericarpium Citri Reticulatae 2-10 part, Fructus Crataegi 2-10 part, binding agent 3-5 part, disintegrating agent 8-10 part and hygroscopic agent 3-5 part。
2. seed shrimp Chinese herbal medicine disease-resistant immunological feed additive as claimed in claim 1, it is characterised in that: the Radix Astragali 8 parts, Radix Isatidis 10 parts, Radix Bupleuri 18 parts, Flos Lonicerae 12 parts, Radix Scutellariae 12 parts, Radix Angelicae Sinensis 8 parts, 7 parts of Radix Glycyrrhizae, 8 parts of Poria, Pericarpium Citri Reticulatae 5 parts and Fructus Crataegi 8 parts。
3. seed shrimp Chinese herbal medicine disease-resistant immunological feed additive as claimed in claim 1, it is characterised in that: described binding agent is one or more in polyvinylpolypyrrolidone, hydroxypropyl methyl cellulose, dextrin, microcrystalline Cellulose, starch slurry, sodium carboxymethyl cellulose, hydroxypropyl cellulose, methylcellulose, ethyl cellulose, gelatin, sucrose, polyvinylpyrrolidone。
4. seed shrimp Chinese herbal medicine disease-resistant immunological feed additive as claimed in claim 1, it is characterised in that: described disintegrating agent is one or more in carboxymethyl starch sodium, dried starch, low-substituted hydroxypropyl cellulose, crospolyvinylpyrrolidone, cross-linking sodium carboxymethyl cellulose。
5. seed shrimp Chinese herbal medicine disease-resistant immunological feed additive as claimed in claim 1, it is characterised in that: described hygroscopic agent is one or more of calcium oxide, magnesium oxide, aluminium oxide, anhydrous cupric sulfate and silica gel。
6. the shrimp as claimed in claim 1 preparation method of Chinese herbal medicine disease-resistant immunological feed additive, it is characterised in that: comprise the following steps:
Step one, weigh the raw material of described parts by weight, adopt that superfine powder is broken is ground into ultra-fine 100 order particle size powders additives；
Step 2, weigh the feedstuff of above-mentioned 1 part of powder additive and 50-200 part, make compound, add water and prepare into serosity according to weight ratio 1:1 mixing；
Step 3, above-mentioned serosity is pumped into spraying pressurized nozzles be sprayed in spray drying tower and carry out less than 60 DEG C atomization dryings become feed particulate material；
Step 4, taking above-mentioned feed particulate material, the binder solution adding concentration 10-15% is in harmonious proportion, and granulates；
Step 5, through less than 60 DEG C dry, granulate, be separately added into disintegrating agent and the hygroscopic agent of described parts by weight, mixing, according to 5g/ sheet weight specification tabletted。
7. a seed shrimp as claimed in claim 6 preparation method of Chinese herbal medicine disease-resistant immunological feed additive, it is characterised in that: described feedstuff is made up of the raw material of following parts by weight: shrimp crack 35-50 part, breaking cellular wall yeast 2-3 part, ocean rhodotorula 2-3 part, astaxanthin 0.1-0.5 part, vitamin D3 0.3-0.8 part, soluble calcium salt 2-4 part, binding agent 3-5 part, disintegrating agent 8-10 part and hygroscopic agent 3-5 part。
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360142A (en) * | 2016-09-22 | 2017-02-01 | 集美大学 | Chinese herbal medicine feed additive capable of controlling diseases and promoting growth for penaeus vannamei and preparation method of additive |
| CN106721416A (en) * | 2016-11-24 | 2017-05-31 | 天津师范大学 | A kind of Chinese herbal medicine trace mineral supplement for blood parrot and preparation method thereof and purposes |
| CN106852419A (en) * | 2016-12-28 | 2017-06-16 | 新昌县柏克动物饲料技术开发有限公司 | Shrimp composite feed additive and preparation method thereof |
| CN107048080A (en) * | 2017-03-14 | 2017-08-18 | 广西精工海洋科技有限公司 | A kind of Penaeus monodon mixed feed |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1887107A (en) * | 2005-12-07 | 2007-01-03 | 湛江粤海饲料有限公司 | Prawn disease resisting additive of compound Chinese herbal medicine |
| CN103931955A (en) * | 2014-05-10 | 2014-07-23 | 厦门市科环海洋生物科技有限公司 | Young litopenaeus vannamei feed and preparation method thereof |
-
2016
- 2016-01-20 CN CN201610037299.7A patent/CN105685526A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1887107A (en) * | 2005-12-07 | 2007-01-03 | 湛江粤海饲料有限公司 | Prawn disease resisting additive of compound Chinese herbal medicine |
| CN103931955A (en) * | 2014-05-10 | 2014-07-23 | 厦门市科环海洋生物科技有限公司 | Young litopenaeus vannamei feed and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360142A (en) * | 2016-09-22 | 2017-02-01 | 集美大学 | Chinese herbal medicine feed additive capable of controlling diseases and promoting growth for penaeus vannamei and preparation method of additive |
| CN106721416A (en) * | 2016-11-24 | 2017-05-31 | 天津师范大学 | A kind of Chinese herbal medicine trace mineral supplement for blood parrot and preparation method thereof and purposes |
| CN106852419A (en) * | 2016-12-28 | 2017-06-16 | 新昌县柏克动物饲料技术开发有限公司 | Shrimp composite feed additive and preparation method thereof |
| CN107048080A (en) * | 2017-03-14 | 2017-08-18 | 广西精工海洋科技有限公司 | A kind of Penaeus monodon mixed feed |
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Application publication date: 20160622 |