CN105640870A - Skin care composition and skin care product with yeast extract - Google Patents

Abstract

The invention discloses a skin care composition and a skin care product with yeast extract. The skin care composition comprises 5-20 parts of the yeast extract, 0.1-5 parts of minerals, 5-25 parts of peptides (in aqueous solution with the concentration of 1*10<-5>%), 5-10 parts of dendrobium officinale extract, 0.1-5 parts of nicotinamide and 45-85 parts of water. The skin care product comprises approximately 0.01%-10% of the skin care composition, approximately 0.1%-40% of oil phases, approximately 60%-98% of water-containing phases, approximately 0.01%-2% of pH (potential of hydrogen) regulators, 3%-10% of emulsifiers, approximately 0.01%-20% of glycosylamine and approximately 0.1%-20% of additive ingredients. The skin care composition and the skin care product have the advantages that the skin care composition and the skin care product contain the yeast extract, polypeptides, the dendrobium officinale extract and the diversified minerals, accordingly, healthful colors of the skins of users can be kept, the skin care composition and the skin care product have functions of fading wrinkle and repairing skin barriers, the skins of the users are healthful, and young activity can bloom.

Description

A kind of skin care compositions and methods containing yeast extract and skin nursing products

Technical field

The present invention relates to the personal care articles of external preparation for skin, specifically a kind of containing yeast extract have skin moisture-keeping, crease-resistant, repair, the skin care compositions and methods of whitening function and the skin nursing products containing this skin care compositions and methods.

Background technology

Lifting along with living standard, consumer's demand to skin care product, be changed into the needs of the multi-functional aspects such as crease-resistant, reparation, whitening, maintenance skin health gradually from the appearance modification on basis, thus it requires skin care product have functional by force, the multiple effect such as safely, effectively.

From the ancient times, yeast is just applied to a lot of aspects of life by the mankind. Before more than 8000 years, time medieval people begin to plantation corn, it is known that use yeast is made wine. Archaeologist reports that Babylonian uses yeast to help wound healing, and Greek's foam that also conventional brewing fermentation produces cleans face and health, with this health keeping skin and beauty.

Yeast extract (yeastextract) be yeast after breaking cellular wall will the wherein extracting such as protein, nucleic acid, vitamin, then through the material rich in active skull cap components such as micromolecular aminoacid, peptide, nucleotide, vitamin of biological enzymolysis. Wherein amino acid content more than 30%, total protein more than 50%, nucleotide more than 10%, it is mainly used in the fields such as food, flavoring agent, cosmetics. Internationally renowned brand adds yeast extract mostly in cosmetics, in order to desalinate wrinkle and to repair skin.

Mineral is the required material of growth promoter in tissue, is maintain the requisite material of skin health. Mineral application in skin care product is also with a long history, can strengthen the spongy layer of collagen protein and elastin laminin, helps full skin to delay wrinkle. Zinc is wound healing and the required antioxidation nutrient of Growth of Cells. Changing in the process of carbon dioxide and water at many enzyme reaction processes, DNA and the RNA polymerase reaction in protein building-up process, and the carbonic acid in carbonic anhydrase, zinc works as transport factor, and participates in the biochemical reaction of extracellular matrix.In corium renewal process, particularly wound healing plays a key effect. Zinc can keep the soda balance in human body, maintains ordinary cells normal function.

In recent years, it receives significant attention because having the natural anti-oxidation defence capability of Skin Cell, starts gradually to be applied to cosmetics. Zinc plays important role in the forming process of superoxide dismutase (a kind of distinctive cellular antioxidants) structure, is a part for skin natural defending system.

Copper is many oxidasic cofactors, and absorption and utilization for ferrum play crucial effect. It can help prevent vitamin C to aoxidize, and promotes the synthesis of dermal elastin. Copper can produce disulphide cross-linking agent in horny layer, promoting natural on-off cycles of hair growth, copper plays an important role in the forming process of tryrosinase, and tryrosinase produces melanin by activating melanocyte, make skin nature blackening and maintain the black colour of skin, contributing to skin-tightening and elasticity.

Peptide, it is primarily present in the positions such as human body skin, skeleton, eyes, tooth, tendon, internal organs (including the heart, stomach, intestinal, blood vessel), its function is the form and the structure that maintain skin and histoorgan, is also the important source material material repairing each damage tissue. In human body skin composition, it is made up of collagen protein by 70%. It plays the effect supporting skin, is referred to as " bone in bone, skin " in skin, is the strong backing of dermal layer of the skin, and skin beauty water is tender smooth flexible, mainly the contribution of collagen protein, and in the skin of baby, the content of collagen protein is sufficient. It may be said that the problem of all skins, such as wrinkle, aging, slack and undisciplined, mottle etc. situation, it is all owing to the loss of collagen protein causes.

Herba Dendrobii, for the perennial herbaceous plant that grows nonparasitically upon another plant of the orchid family. Effect for oral administration of Herba Dendrobii mainly has: Yin-nourishing and body fluid promoting maintenance the five internal organs, health invigorating, improve immunity, strengthening the tendons and bones, opposing rheumatism, strengthen the spleen and stomach, function of gallbladder promoting, treating the liver biliary diseases, prevent and treat diabetes, suppress tumor, reduce Radiotherapy chemotherapy side effect, item eye protection and moisturizing skin moistening, life lengthening etc. And the performance of Herba Dendrobii the above effect, it is all realize with method for oral administration. Southern Dynasties's TAO Hong-Jing " book on Chinese herbal medicine is through note " is recorded: Herba Dendrobii longue meat, by skin pathogenic heat miliaria gas. After the Tang and Song Dynasty, having a lot of record maintaining skin about imperial palace lady with Herba Dendrobii, famous just has Wu Tse-tien and the Empress Dowager. Active polysaccharide energy human activin rest cell contained by Herba Dendrobii, makes cell function again, moreover it is possible to strengthening cell viability, the great-hearted words of cell, the epidermal tissue being made up of cell is also just more full glossy expressively. Colloid contained by Herba Dendrobii, it is possible to supplement collagen protein in human body skin; Show that skin has the skin care effect such as anti-inflammation, moist moisturizing, injury repairing, antioxidation.

Nicotinic acid and nicotiamide are all water soluble vitamins, i.e. vitamin B3. Nicotiamide (also referred to as niacin amide) is coenzyme nicotinamide adenine dinucleotide (NAD) and the phosphatic constituent of NAD. Nicotinamide deficiency can cause pellagra, and oral nicotiamide is effective to bullous pemphigoid. Topical application nicotiamide can reduce transepidermal water loss, improves horny layer moisture. Additionally, nicotiamide can also promote the synthesis of keratin and ceramide, it was reported that local uses nicotiamide can reduce old and feeble skin of face sallow degree, reduce wrinkle, erythema and pigmentation speckle.

Summary of the invention

It is an object of the invention to provide a kind of skin care compositions and methods containing yeast extract, it contains yeast extract, polypeptide, Herba Dendrobii extract and several mineral materials simultaneously, both the skin health colour of skin can have been kept, there is again desalination wrinkle, repair skin barrier function, make skin health, call forth one's youthful vigor.

Summary of the invention

" skin nursing products " described herein refer to that the product contained includes but not limited to moisturizing water preparation, essence, skin nursing breast/frost etc. for processing or nurse or moisturizing in some way, improving the product of skin.

Except special instruction, all percentage ratios used herein, number and ratio are all with the weighing scale of total composition.

Unless otherwise indicated, the environmental condition referring to about atmospheric pressure, about 50% relative humidity and about 25 DEG C used herein to " environmental condition ".

The present composition can include, by or be substantially grouped into by the component of the present invention and other one-tenth as herein described. Predicate used herein " substantially by ... composition " refer to that compositions or component can include supplementary element, as long as described supplementary element will not substantially change the basic and new characteristic of claimed compositions or method.

Herein, " regulation of skin situation " refers to the outward appearance and/or sensation of improving skin, such as more smooth outward appearance and/or sensation. " regulation of skin situation " refers to visually and/or obtains skin appearance and the perceptible positive change of sensation aspect in sense of touch herein. Described beneficial effect can be chronic beneficial effect and can include one or more of: reduces the appearance of wrinkle and coarse deep stricture of vagina, microgroove, crackle, lump and enlarged pores and increases skin shine, brightness.

The present composition can be used for skin nursing products, and its non-limiting purposes includes wetting agent, conditioner, anti-senescence compounds, skin lightening compound and their combination.

The skin nursing products of the present invention may also include other composition various, will be described below.

Detailed Description Of The Invention

First technical problem that the invention solves the problems that is to provide the skin care compositions and methods containing yeast extract with crease-resistant, moisturizing, reparation skin, and its non-limiting purposes includes wetting agent, conditioner, anti-senescence compounds, skin lightening compound and their combination.

Second technical problem that the invention solves the problems that is to provide the skin nursing products containing the skin care compositions and methods containing yeast extract.

The preparation method that the 3rd technical problem that the invention solves the problems that is to provide the skin nursing products of the skin care compositions and methods containing yeast extract.

For solving above-mentioned first technical problem, the present invention skin care compositions and methods containing yeast extract, comprise the raw material of following parts by weight:

The process of preparing of the above-mentioned skin care compositions and methods containing yeast extract is:

1) preparation of Herba Dendrobii aqueous solution:

Take Herba Dendrobii Dendrobiumcandidum100g, add 9 times amount deionized waters, after crushing with pulverizer, filter, the extract obtained solution made, obtain the Herba Dendrobii extracting solution of content 10%.

2) being sequentially added in agitated kettle by yeast extract, mineral, peptide, Herba Dendrobii extract, nicotiamide, add deionized water, benefit to weight ratio is 100%, open stirring 30 minutes to 1 hour, it is sufficiently mixed uniformly to all materials, stops stirring, standby.

Described yeast extract is commercially available prod Biodynes series, Phytohyaluronate (all deriving from Qi company difficult to understand), yeast elite extract E100, yeast essence G3, yeast essence E300, yeast essence M60 (all deriving from Angel Yeast), overlay film culture propagation filtrate, SKHPitera, derives from one or more the combination in Kashiwayama;Preferably, amino acid content more than 30% in described yeast extract, total protein content more than 50%, nucleotide content more than 10%; Preferably, yeast extract 5-10 part.

Described mineral is one or more the combination in commercially available prod BiominMarineAcqua-Biomins series (being all from Qi company difficult to understand) or SEPITONICM3 (deriving from Seppic); Preferably, mineral 1-3 part.

Described peptide includes but not limited to dipeptides, tripeptides, tetrapeptide, pentapeptide and six peptides and their derivant. " peptide " used herein not only refers to naturally occurring peptide but also refer to the peptide of synthesis. Can be additionally used in the present invention be naturally-occurring and commercially available containing peptide combinations. When involved in the compositions of the present invention time, the preferred content of peptide is about lx10 by weight of the composition^-6% to about 10%, more preferably about lx10^-6% to about 0.5%, even more preferably about lx10^-5% to about 0.05%.

Described Herba Dendrobii extract is the aqueous solution of self-control 2%, it is preferable that Herba Dendrobii extract 5-8 part;

Preferably, nicotiamide 2-3 part; Preferential commercially available prod, nicotiamide PC, derive from DSM; Nicotiamide, derives from Lonza.

For solving above-mentioned second technical problem, the skin nursing products of a kind of skin care compositions and methods containing yeast extract, skin nursing products of the present invention may also include other composition various, and specifically details are as follows:

Oil phase

The skin nursing products of the present invention, described oil phase is considered not miscible with aqueous phase, and oiliness compound can be included, such as natural and artificial oil, and other shows the lyophobic dust of limited solubility in aqueous phase, include but not limited to oil-soluble ingredients, oil-soluble sun screens and other oil-soluble skin care active material; Lipoid and oil may be from animal, plant or oil, and can be naturally occurring or synthetic.

Suitable oiliness compound includes ethereal oil and nonvolatile oil, includes but not limited to hydrocarbon ils and wax, silicone oil, fatty alcohol and derivative of fatty acid, cholesterol, cholesterol derivative, vegetable oil, vegetable oil derivatives, acetin, Arrcostab, alkenyl ester, lanoline, wax ester, their salt, isomer and derivant and their combination.

It is applicable to the limiting examples of nonvolatile hydrocarbon ils herein and wax and includes vaseline, mineral oil, microwax, polyolefin, paraffin, hydrosqualene, polyalphaolefin, the polyisobutylene of hydrogenation and their combination.

The limiting examples being applicable to non-volatile silicone oil herein includes: dimethicone copolyol, Dimethicone Crosspolymer, dimethyl polysiloxane, diethyl polysiloxanes, the C1-30 alkyl polysiloxane of mixing, phenyl dimethicones, dimethiconol and their combination. the limiting examples being applicable to Dimethicone Crosspolymer herein includes: acrylate/bis-hydroxypropyl Dimethicone Crosspolymer, C30-45 alkyl 16/octadecyl Dimethicone Crosspolymer, propylene/bis-hydroxypropyl Dimethicone Crosspolymer, C30-45 alkyl 16/octadecyl Dimethicone Crosspolymer, 16/octadecyl Dimethicone/Vinyl Dimethicone cross linked polymer, Dimethicone Crosspolymer, Dimethicone Crosspolymer-3, polydimethylsiloxane/phenyl vinyl Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone cross linked polymer, diphenyl dimethicone cross linked polymer, divinyl polydimethylsiloxane/Dimethicone Crosspolymer, GRANSIL GCM-5 and their mixture.

Can be used for the ethereal oil of the present invention and be selected from by the following component formed: volatile silicone oils, volatile hydrocarbon and their mixture, it can be saturated or unsaturated for can be used for the ethereal oil of the present invention, can have aliphatic character, and be straight or branched or comprise alicyclic ring or aromatic ring.

The enforcement of preferred volatile hydrocarbon includes the isoparaffin of Fancol ID and C12-C15.

The example of preferred volatile silicone oils includes: the cyclo-methicone (cyclomethicone) of various viscosity, such as DowCorning200, DowCorning244, DowCorning245, DowCorning344 and DowCorning345 (all deriving from DowCorningCorp.); SF-1204 and SF-1202 organosilicon liquid (all derives from MOMENTIVE) and KF-995 (deriving from Shin-EtsuChemical). The preferred example of Linear volatile silicone includes KF-96A-1cs, KF-96L-1.5cs, KF-96L-2cs, KF-96A-5cs (all deriving from Shin-EtsuChemical). The preferred example of volatile silicone oils of side chain includes TMF-1.5 (deriving from Shin-EtsuChemical).

Aqueous phase

Skin nursing products of the present invention comprise continuous aqueous phase, and described aqueous phase comprises aqueous carrier and thickening agent. Described aqueous phase can further include other hydroaropic substance showing limited solubility in oil phase, includes but not limited to water soluble ingredient, water-soluble sunscreens and other water-soluble skin care active substance.

Described compositions comprises about 60% to about 98%, it is preferable that the aqueous phase of about 65% to about 95%.

Aqueous carrier

The aqueous phase of the present invention comprises aqueous carrier to provide continuous phase. According to the compatibility and product of other component needed for other characteristic select content and the kind of described carrier.

The aqueous solution of water and lower alkyl alcohol is included for the carrier of the present invention. Lower alkyl alcohol for the present invention is the monohydric alcohol with 1 to 6 carbon atom, more preferably ethanol. Preferably, aqueous carrier is substantially water. Deionized water is preferably used. It is also possible to use the water from natural source comprising mineral cation, this depends on the characteristic needed for product.

The pH of the present composition is preferably from about 4 to about 8. When comprising skin benefit agent in aqueous phase, can be the value being provided that active skin benefit agents optimal efficacy by pH regulator. In order to obtain required pH, buffer agent and other pH adjusting agent can be comprised. PH adjusting agent suitable herein includes acetate, phosphate, citrate, sodium hydroxide, triethanolamine, aminomethylpropanol and carbonate.

Thickening agent

The aqueous phase of the present invention comprises about 0.1% to about 3%, it is preferable that the thickening agent of about 0.1% to about 2%, and described thickening agent includes thickening agent, gellant and structuring agents. According to the compatibility and product of other component needed for other characteristic select content and the classification of thickening agent.

The non-limiting classification of thickening agent includes cross-linked polyacrylate polymer and copolymer, the polyacrylate polymers of hydrophobically modified and copolymer, polyacrylamide polymers and copolymer, polypropylene acyl group dimethyltaurate, the polymer of aminomethylpropanol (AMP)-Ji and copolymer, polysaccharide and natural gum. What can be used for the present invention is carboxylic acid/carboxylate copolymer. Can be used for carboxylic acid/carboxylate copolymer limiting examples herein to include: commodity are called the CTFA title acrylate/acrylic acid C10-30 alkyl ester cross-linked polymer (all deriving from Noveon) of PemulenTR-1, PemulenTR-2, CarbopolUltrez10, CarbopolUltrez20, CarbopolUltrez21, Carbopol1342, Carbopol1382 and CarbopolETD2020.The additional water-soluble polymer being highly available for herein commercially available includes the xanthan gum of commodity KELTROL series by name, derives from CPKelco; Commodity are called the carbomer (all deriving from Noveon) of Carbopol934, Carbopol940, Carbopol950, Carbopol980 and Carbopol981; Acrylate/steareth-20 methacrylate copolymer of commodity ACRYSOL22 by name (derives from (Rohm&Hass); Having polyacrylamide or the polyacrylate/salt of trade name SEPIGEL series, commodity are called SEPIGEL305, SEPIGELEG, SEPIGELNS, SEPIGELFL, SEPIGELINS100, SEPIPLUS 400, SEPINOVEMT10 (all deriving from SEPPIC); The polyglycerolmethacrylate of commodity LUBRAGELNP by name, and commodity LUBRAGELOIL by name, the mixture (all deriving from ASHLAND) of polyglycerolmethacrylate, propylene glycol and Gantrez AN-119; Commodity be called CARBOWAXPEGs, POLYOXWSRs and UCONFLUIDS based on oxirane and/or epoxypropane polymer (all deriving from DOWCHEMICAL).

Another kind of thickening agent includes structuring agents. The limiting examples of structuring agents includes saturated C12-C30 fatty alcohol, comprise the saturated C12-C30 fatty alcohol of about 1 to about 5 moles of ethylene oxide, saturated C12-C30 glycerol monoethers, saturated C12-C30 monoglyceride and their mixture, its fusing point having at least about 40 DEG C. The group of currently preferred structuring agents choosing freely following composition: stearyl alcohol, spermol, docosanol, glyceryl monostearate.

Emulsifying agent

The skin nursing products of the present invention can comprise emulsifying agent, for being disperseed by oil phase and being suspended in described aqueous phase. When the skin nursing products of the present invention comprise emulsifying agent, it comprises less than 10%, it is preferable that less than 5%, and the emulsifying agent more preferably no more than 3%.

Numerous emulsifiers can be used for herein. in one embodiment, the limiting examples of emulsifying agent includes nonionic and anion emulsifier such as sugar ester and polyester, alkoxylated sugar esters and polyester, the C1-C30 fatty acid ester of C1-C30 fatty alcohol, the alkoxy derivative of the C1-C30 fatty acid ester of C1-C30 fatty alcohol, the alkoxylated ether of C1-C30 fatty alcohol, the polyglyceryl ester of C1-C30 fatty acid, the C1-C30 ester of polyol, the C1-C30 ether of polyol, alkyl phosphate, polyoxyalkylene fatty ether phosphate ester, fatty acid amide, acyl lactylates soap, and their mixture.

Can be used for the non-limiting example of other emulsifying agent herein to include: Polyethylene Glycol 20, sorbitan-laurate (TWEEN-20), steareth-20, cetearyl polyoxyethylene ether-20, PPG-methyl glucose ether distearate, ceteth-10, polysorbate 80, cetyl phosphate, cetyl phosphate potassium, cetyl phosphate diethanolamine, polysorbate 60, tristerin, PEG-100 stearate, polyoxyethylene 20 sorbitan trioleate (polysorbate 85), sorbitan-laurate, polyoxyethylene 4 lauryl ether sodium stearate, polyglyceryl-4 isostearate, lauric acid hexyl ester, PPG-methyl glucose ether distearate, ceteth-10, cetyl phosphate diethanolamine, Cremophor RH40, PEG-60 castor oil hydrogenated, glycerin polyether-25PCA isostearate, and their mixture.

In another embodiment, described emulsifying agent is silicone emulsifiers, including organically-modified organopolysiloxane (silicone surfactant), such as dimethicone copolyol.

Osamine

The skin nursing products of the present invention can comprise the osamine of safe and effective amount, is also known as amino sugar. As used herein, " osamine " refers to the amine derivative of hexose. Said composition preferably comprises by weight of the composition about 0.001% to about 20%, and preferably about 1% to about 10%, the even more preferably about osamine of 2% to about 5%. Can be used for the example of the osamine of the present invention and include glycosamine, N-acetyl glucosamine, mannosamine, N-acetyl mannosamine, galactosamine, GalNAc. May be preferably used for being glycosamine herein. Additionally, it is possible to use the combination of two or more osamines.

Sunscreen

The skin nursing products of the present invention can comprise one or more sunscreen actives (or " sunscreen ") and/or UV absorbent. " sunscreen actives " includes sunscreen and physical sunscreen frost herein. Sunscreen actives material and ultra-violet absorption can be organic or inorganics.

Supplementary element

Suitable wetting agent includes but not limited to polyhydric alcohol, such as poly alkylene glycol and their derivant. Illustrative for propylene glycol, dipropylene glycol, polypropylene glycol, Polyethylene Glycol, sorbitol, hexanediol, 1,3 butylene glycol, the glycerol of ethoxylation, propenoxylated glycerol and their mixture.

Suitable emollient includes but not limited to hydrocarbon, fatty acid, fatty alcohol and ester.

Suitable non-vitamin antioxidants and free radical scavenger include but not limited to BHT (butylated hydroxy-methylbenzene), L-ergothioneine (with TH work OTANETM for trade name), tetrahydrocurcumin, Aden's perfume base malonic acid ethylhexyl (with OXYNETM for trade name), 18 carbon-8-alkene-1,16-dicarboxylic acids (octadecene diacid, ARLATONETMDioicDCA, derive from CROAD), ubiquinone (coenzyme Q10), Folium Camelliae sinensis extract, include green tea extract and their combination.

Suitable plant sterol and/or phytohormone example include but not limited to sitosterol, stigmasterol, campesterol, campesterol.

Suitable antiinflammatory includes but not limited to glycyrrhizic acid (being also known as glycyrrhizin, glycyrrhizic acid and glycyrrhizin), glycyrrhetinic acid, other Radix Glycyrrhizae extract and their combination.

Other available skin care actives includes moisturizing and/or conditioner, as being hydrolyzed Herba Violae Hortensis extract, derives from Silab with Aquaphyline; Rhamnose is releived agent, derives from sethic with RHAMNOSOFT; Glycine betaine, derives from EVONIK with TegoNaturalBetaine; Sarcosine, skin lightening agent such as kojic acid, mulberry extract, arbutin, alginate jelly, Aloe extract, Aloe powder and their mixture.

When deployed, the described skin care compositions and methods containing yeast extract preferably comprises by the weighing scale of compositions about 0.01% to about 10%, it is more preferable to about 2% to 5%.

Described compositions can further include at least one compound, the group of described compound choosing freely following composition: skin care actives, sunscreen, wetting agent and emollient.

Prepared by skin nursing products

The skin nursing products that the local of the present invention uses can be configured to skin of face cosmetics, eye cosmetic, skin facial film, skin cream, skin gel, eye gel, eye cream, lip gel, lip frost, cosmetics, foundation cream or other commonly known skin nursing products any.

The present invention has following Advantageous Effects:

1, a kind of skin care compositions and methods containing yeast extract of the present invention, it contains yeast extract, polypeptide, Herba Dendrobii extract and several mineral materials simultaneously, both can keep the skin health colour of skin, have again desalination wrinkle, repair skin barrier function, make skin health, call forth one's youthful vigor.

2, the compositions of the present invention may also provide additional beneficial effect, and described additional beneficial effect includes stability, notable (consumer the is unacceptable) skin irritation of nothing and good aesthetic.

Accompanying drawing explanation

Fig. 1 is that volunteer uses front and back wrinkle number minimizing amount.

Detailed description of the invention

Below by way of concrete preferred embodiment in conjunction with compliance test result test example content, the present invention is described in further detail, but the present invention is not limited in below example.

Embodiment 1 to 8 represents the limiting examples of skin care compositions and methods as herein described, is suitable for being coated on collenchyme according to approach described herein. Said composition is suitable to be made by:

Embodiment 1-4

The skin of embodiment 1-4 protects product (elite/gelled composition) constitutive material and weight percent content is as shown in table 1 below.

The raw material composition of the skin nursing products (elite/gelled composition) of table 1 embodiment 1-4

* 1, acrylate copolymer Carbopol940: derive from Noveon;

* 2, acrylate copolymer UltreZ21: derive from Noveon;

* 3, KELTROLCG-T: derive from CPKelco;

* 4PemulenTR-2: derive from Noveon;

* 5LUBRAGELOIL: derive from ISP;

* 6 hyaluronic acids: derive from Shandong Fu Ruida;

* 7 glycyrrhizic acid dipotassiums: derive from and general plant Pharmaceutical;

* 8OKINACEA: derive from GELYMA;

* 9 glycine betaines: derive from EVONIK;

* 10PE9010: derive from Shu Mei company of Germany;

C phase constituent-skin care compositions and methods therein, its raw material components formula and weight portion content are as shown in table 2 below.

The raw material components formula of table 2 skin care compositions and methods

Ingredient names	Content (weight portion)
		Yeast extract	5 parts
Mineral	2 parts
		Peptide (lx10-5The aqueous solution of % concentration)	2 parts
Herba Dendrobii extract (10% aqueous solution)	1 part
		Nicotiamide	2 parts
Water	88 parts

Wherein, the process for making of skin care compositions and methods is as follows:

1) preparation of Herba Dendrobii aqueous solution:

Take Herba Dendrobii Dendrobiumcandidum100g, add 9 times amount deionized waters, after crushing with pulverizer, filter, the extract obtained solution made, obtain the Herba Dendrobii extracting solution of content 10%.

2) being sequentially added in agitated kettle by yeast extract, mineral, peptide, Herba Dendrobii extract, nicotiamide, add deionized water, benefit to weight ratio is 100%, open stirring 30 minutes to 1 hour, it is sufficiently mixed uniformly to all materials, stops stirring, standby.

Embodiment 1 to 4 provides elite/gelled composition, and suitable following processing step prepares:

1) A phase: use suitable agitator (such as anchor formula stirring paddle, propeller or work KAT25) to be mixed in a reservoir by all of composition, heating is to 80 �� 2 DEG C, and insulated and stirred is until described phase homogenization;

2) B phase component joining A phase successively, keep temperature 80 �� 2 DEG C, insulated and stirred is until described phase homogenization;

3) opening cooling water, cooling material, to 45 DEG C, adds C phase materials, and mixes until homogenization;

4) cooling material is to 40 DEG C, samples censorship. After the assay was approved, stirring, discharging are stopped.

The skin of embodiment 5-8 protects product (emulsion/gel cream composition) constitutive material and weight percent content is as shown in table 3 below.

The raw material composition of the skin nursing products (emulsion/gel cream composition) of table 3 embodiment 5-8

* 1ALGISIUMC, derives from EXSYMOL

* 2LecinolS-10, derives from NIKKOL

* 3Brij721, derives from CRODA

* 4SIMULSOL165, derives from SEPPIC

* 5ABILCare85, derives from EVONIK

* 6MONTANOVL, derives from SEPPIC

* 7TEGOSOFTCT, derives from EVONIK

* 8Plandool-G, derives from Nippon Seika K.K.

* 9LANOL99, derives from SEPPIC

* 10DC200100cst, derives from DowCorningCorp

* 11SILSOFT034, derives from MOMENTIVE

* 12DC9040, derives from DowCorningCorp

* 13 De Minshu, derive from Symrise

* 14 rhamnose are releived agent, derive from Sethic

D phase supplementary element therein: skin care compositions and methods, its raw material components formula and content are as shown in table 4 below.

The raw material components formula of table 4 skin care compositions and methods

Ingredient names	Content (weight portion)
		Yeast extract	5 part 11-->
Mineral	2 parts
		Peptide (lx10-5The aqueous solution of % concentration)	5 parts
Herba Dendrobii extract (10% aqueous solution)	10 parts
		Nicotiamide	3 parts
Water	75 parts

Wherein, the process for making of skin care compositions and methods is as follows:

1) preparation of Herba Dendrobii aqueous solution:

Take Herba Dendrobii Dendrobiumcandidum100g, add 9 times amount deionized waters, after crushing with pulverizer, filter, the extract obtained solution made, obtain the Herba Dendrobii extracting solution of content 10%.

2) yeast extract, mineral, peptide, Herba Dendrobii extract, nicotiamide are sequentially added in agitated kettle, add deionized water, open stirring 30 minutes to 1 hour, be sufficiently mixed uniformly to all materials, stop stirring, standby.

Embodiment 5 to 8 provides emulsion/gel cream composition, and suitable following processing step prepares:

1) an A phase: use suitable agitator (such as anchor formula stirring paddle! Propeller or work KAT25) all of composition is mixed in a reservoir, heating is to 80 �� 2 DEG C, and insulated and stirred is until described phase homogenization.

2) a B phase: use suitable agitator (such as anchor formula stirring paddle! Propeller or work KAT25) all of composition is mixed in a reservoir, heating is to 80 �� 2 DEG C, and insulated and stirred is until described phase homogenization.

3) being slowly added in A phase by B, mixing is until batch of material homogenization, emulsifying 8 minutes, and insulated and stirred, after 10 minutes, opens cooling water, limit stirring cooling;

4) cooling material is to 60 DEG C, adds C phase materials, and mixes until homogenization;

5) continue cooling material to 45 DEG C, be sequentially added into D phase materials and mix, until material homogenization;

6) cooling material is to 40 DEG C, samples censorship. After the assay was approved, stirring, discharging are stopped.

Effect application test example

1, facial skin performance evaluation is improved:

Method of testing:

Volunteer selects: men and women has, 25��45 years old, healthy, without dermatosis and allergies, non-sensitive skin, attitude is conscientious, it is possible to by Normalization rule cosmetics, and cooperating personnel complete appraisal on request, there is certain expressive faculty, the impression after energy actual response use.

Volunteer's number: 20 people

Evaluation index: facial skin elasticity, skin shine, near the eyes wrinkle quantity

Test zone: face, including canthus, now, cheek region

Test period: 8 weeks

(1), skin elasticity test: skin elasticity is also one of important symbol judging skin aging, and carrying out skin elasticity mensuration is that skin aging detects requisite project.

Principle: use MPA580 elasticity tester, by test the size replying deformation of skin investigate make to apply some make up after the change of skin elasticity, evaluate the senile-resistant efficacy of cosmetics.

By above 20 people are used embodiment 1 to 8 and placebo respectively, skin elasticity is tested, analysis of experimental data is collected such as following table:

Table 5 skin elasticity improves information slip

Analysis of conclusion: can be seen that skin elasticity is improved significantly by the embodiment using skin care compositions and methods by above experimental data, consumption is more big, and effect is more notable, uses time more long-acting fruit more obvious, after using 8 weeks, maximum skin elasticity degree of improvement is 32.5%.

(2), wrinkle test

It is the most important feature of skin aging that wrinkle is formed, by the impact of many endogenous factors such as heredity, endocrine change, while extrinsic factor such as ultraviolet, smoking etc. can significantly accelerated, increase the weight of the formation of wrinkle. Wrinkle is the initial sign of skin aging. Wrinkle develops further, can form pleat, namely deeper on skin pleat. The order occurred is usually forehead, upper palpebra inferior, paropia, mouth week. In general, after 25 years old, the ageing process of skin starts, and wrinkle occurs gradually.Namely human body frons may occur in which wrinkle, is on the increase and by increasing the weight of when 30��40 years old, crows-feet occurs in tail of the eye portion simultaneously, and after 50 years old, deep wrinkles occurs, forms more typical aging appearance. Carry out the mensuration of wrinkle of skin, for judging that skin aging is particularly significant.

Experimental technique: choose 10 individualities having obvious wrinkle, use product containing skin care compositions and methods, and to contrast wrinkle quantity of taking pictures before using and after using certain time number and the change of the wrinkle depth to observe the anti-crape effect of skin care compositions and methods.

By several groups of pictures it can be seen that number and the wrinkle depth of wrinkle quantity are all significantly improved by skin care compositions and methods. Concrete wrinkle number situation uses front and back as shown in table 6 below.

The situation unit of trier's wrinkle number before and after table 6 is on probation: bar

Being illustrated by Fig. 1 and Biao 6, skin care compositions and methods is notable to improving wrinkle of skin effect, can be widely used in skin of face skin care products.

2, human body skin stimulates test:

This skin care compositions and methods has been carried out following experiments;

Acute skin irritation is tested: nonirritant

Acute ocular irritation test: nonirritant

Oral toxicity is tested: LD50 oral (50) is no less than 15ml/kg

Accumulation uses test: within continuous 14 days, do not observe erythema and edema

Cutaneous sensibility is tested: do not observe erythema and edema

Skin phototoxicity is tested: do not observe erythema and edema

Photosensitivity is tested: do not observe erythema and edema

Human body patch test: after applying latter 48 hours, all 20 aspirations do not have negative reaction

Above experimental data illustrates, skin care compositions and methods is safe.

The above, it it is only presently preferred embodiments of the present invention, not the present invention is done any pro forma restriction, therefore it is every without departing from technical solution of the present invention content, according to any simple modification, equivalent variations and modification that above example is made by the technical spirit of the present invention, all still fall within the scope of technical solution of the present invention.

Claims (10)

1. the skin care compositions and methods containing yeast extract, it is characterised in that: comprise each raw material components of following parts by weight:

2. the skin care compositions and methods containing yeast extract according to claim 1, it is characterised in that:

Described yeast extract be yeast after breaking cellular wall will the wherein extracting such as protein, nucleic acid, vitamin, then through the material rich in active skull cap components such as micromolecular aminoacid, peptide, nucleotide, vitamin of biological enzymolysis; Wherein amino acid content more than 30%, total protein more than 50%, nucleotide more than 10%, it is preferable that yeast extract 5-10 part;

Described peptide includes but not limited to dipeptides, tripeptides, tetrapeptide, pentapeptide and six peptides and their derivant;

Described Herba Dendrobii extract is the aqueous solution of self-control 2%, it is preferable that Herba Dendrobii extract 5-8 part;

Nicotiamide 2-3 part.

3. the skin care compositions and methods containing yeast extract according to claim 1, it is characterised in that: it is prepared by prepared by method step:

1) prepare Herba Dendrobii aqueous solution, comprise following technique:

Take Herba Dendrobii Dendrobiumcandidum100g, add 9 times amount deionized waters, after crushing with pulverizer, filter, the extract obtained solution made, obtain the Herba Dendrobii extracting solution A of content 10%;

2) yeast extract, mineral, peptide, Herba Dendrobii extract, nicotiamide are sequentially added in agitated kettle, add deionized water, open stirring 30 minutes to 1 hour, be sufficiently mixed uniformly to all materials, stop stirring, standby.

4. skin nursing products, it is characterised in that: it is containing, for example the skin care compositions and methods according to any one of claim 1-3, and this skin care compositions and methods accounts for the 0.01% to about 10% of skin nursing products total amount, it is preferable that about 2% to 5%; These skin nursing products also comprise each raw material components of following percentage by weight:

The oil phase of 0.1% to about 40%;

The aqueous phase of 60% to about 98%;

The pH adjusting agent of 0.01% to about 2%;

The emulsifying agent of 3%-10%

The osamine of 0.001% to about 20%;

The supplementary element of 0.1% to about 20%.

5. skin nursing products according to claim 4, it is characterised in that:

Described oil phase is considered not miscible with aqueous phase, and oiliness compound can be included, such as natural and artificial oil, and other shows the lyophobic dust of limited solubility in aqueous phase, includes but not limited to oil-soluble ingredients, oil-soluble sun screens and other oil-soluble skin care active material; Lipoid and oil are available from animal, plant or oil, and can be naturally occurring or synthetic;

The aqueous phase of about 65% to about 95%; Described aqueous phase comprises aqueous carrier and thickening agent; Described aqueous phase can further include other hydroaropic substance showing limited solubility in oil phase, includes but not limited to water soluble ingredient, water-soluble sunscreens and other water-soluble skin care active substance.

6. skin nursing products according to claim 5, it is characterised in that: described aqueous carrier includes the aqueous solution of water and lower alkyl alcohol; Lower alkyl alcohol for the present invention is the monohydric alcohol with 1 to 6 carbon atom, more preferably ethanol.

7. skin nursing products according to claim 5, it is characterised in that: described aqueous phase comprises about 0.1% to about 3%, it is preferable that the thickening agent of about 0.1% to about 2%, and described thickening agent includes thickening agent, gellant and structuring agents.

8. skin nursing products according to claim 4, it is characterised in that: said composition preferably comprises by weight of the composition about 10%, it is even preferred to the osamine of about 2% to about 5%; Can be used for the example of the osamine of the present invention and include glycosamine, N-acetyl glucosamine, mannosamine, N-acetyl mannosamine, galactosamine, GalNAc.

9. skin nursing products according to claim 4, it is characterised in that: described supplementary element comprises wetting agent, emollient, non-vitamin antioxidants and free radical scavenger, suitable plant sterol and/or phytohormone, antiinflammatory, other available skin care actives include moisturizing and/or conditioner;

It further comprises wetting agent, conditioner, anti-senescence compounds, skin lightening compound and their combination.

10. skin nursing products according to claim 4, it is characterised in that: be prepared by following processing step:

1) A phase: use suitable agitator (such as anchor formula stirring paddle, propeller or work KAT25) to be mixed in a reservoir by all of composition, heating is to 80 �� 2 DEG C, and insulated and stirred is until described phase homogenization;

2) B phase component joining A phase successively, keep temperature 80 �� 2 DEG C, insulated and stirred is until described phase homogenization;

3) opening cooling water, cooling material, to 45 DEG C, adds C phase materials, and mixes until homogenization;

4) cooling material is to 40 DEG C, samples censorship. After the assay was approved, stirring, discharging are stopped.